Pharmacodynamics. A blocker of dopamine and serotonin receptors, inhibits the chemoreceptors of the brain, weakens the sensitivity of the visceral nerves that transmit impulses from the pylorus and duodenum to the vomiting center. Through the hypothalamus and parasympathetic division of the vegetative nervous system regulates and coordinates the motor activity of the upper digestive tract. Increases the tone of the stomach and intestines, accelerates gastric emptying, reduces gastrostasis, prevents pyloric and esophageal reflux, and stimulates intestinal peristalsis. It has antiemetic effect in vomiting of various origins (except for vomiting of a psychogenic and vestibular nature). It normalizes the secretion of bile, reduces the spasm of the sphincter of Oddi, does not change its tone, eliminates dyskinesia of the gallbladder.
Pharmacokinetics. It is rapidly and completely absorbed after oral administration. The maximum concentration in blood plasma is reached within 30-120 minutes after administration. The onset of action on the digestive tract is noted 20-40 minutes after ingestion. The antiemetic effect lasts for 12 hours. 13-30% of metoproclamide binds to blood plasma proteins. The volume of distribution is 3.5 l / kg. It is metabolized in the liver. The half-life is 4-6 hours. Within 24-72 hours, up to 80% of the administered dose is excreted in the urine, about 30% - unchanged. Penetrates the BBB and the placental barrier, excreted in breast milk.
With intravenous administration, the onset of action on the digestive tract is noted after 1-3 minutes, with intramuscular administration - after 10-15 minutes.

Indications for the use of the drug Cerucal

Upper gastrointestinal motility disorders (eg, irritable stomach syndrome, heartburn, reflux esophagitis, and functional pyloric stenosis); nausea, urge to vomit and vomiting (with liver and kidney disease, traumatic brain injury, migraine and due to increased sensitivity to drugs); paresis of the stomach of diabetic genesis; when carrying out X-ray diagnostics of diseases of the stomach and small intestine.

Application of the drug Cerucal

Tablets
Adults and adolescents over the age of 14 are prescribed orally 10 mg 3-4 times a day.
Recommended for children aged 3 to 14 single dose is 0.1 mg / kg, the maximum daily dose is 0.5 mg / kg.
The tablets are taken orally, approximately 30 minutes before meals.
The duration of the course of treatment depends on the severity and course of the disease. The usual course of treatment is 4-6 weeks. In some cases, treatment can be continued up to 6 months. In the presence of renal failure, the dose of the drug is selected taking into account the severity of renal dysfunction.
Injection
The injection solution is injected intramuscularly or intravenously slowly. Adults and adolescents over the age of 14 are injected intramuscularly and intravenously, 2 ml of Cerucal solution 3-4 times a day (single dose is 10 mg, daily dose is 30-40 mg of metoclopramide).
For children aged 3 to 14 years, the recommended single dose is 0.1 mg / kg of body weight, the maximum daily dose is 0.5 mg / kg.
Appointment of metoclopramide in high doses for nausea and vomiting caused by the use of cytostatic agents:
Dosing regimen 1
By short-term intravenous drip infusion (for 15 minutes), Cerucal is administered at a dose of 2 mg / kg 30 minutes before the administration of the cytostatic agent, as well as after 1.5; 3.5; 5.5 and 8.5 hours after application of the cytostatic agent.
Dosing regimen 2
By continuous intravenous drip infusion, Cerucal is administered at a dose of 1 (0.5) mg / kg for an hour, starting 2 hours before the use of a cytostatic agent, then at a dose of 0.5 (0.25) mg / kg for an hour within 24 hours after using the cytostatic agent.
Cerucal is used throughout the entire period of treatment with a cytostatic agent. Each short-term intravenous drip infusion is carried out within 15 minutes after the previous dilution of the dose of Cerucal in 50 ml of infusion solution. Cerucal for injection can be dissolved with isotonic sodium chloride solution or 5% glucose solution.
Note
Solution Cerucala for injection should not be mixed with alkaline infusion solutions.

Contraindications to the use of the drug Cerucal

Hypersensitivity to the drug; pheochromocytoma; mechanical intestinal obstruction; intestinal perforation and gastrointestinal bleeding; prolactin-dependent tumors; in patients with epilepsy or in patients with increased convulsive readiness (extrapyramidal movement disorders); first trimester of pregnancy and lactation; in newborns and children under 3 years of age.
For children aged 3-14 years, as well as pregnant women in the II-III trimester, metoclopramide is prescribed only for health reasons.
For patients with reduced renal function, the drug is prescribed in reduced doses.
Due to the content of sodium sulfite, the injection solution of Cerucal should not be prescribed to patients with asthma with hypersensitivity to sulfite.

Side effects of the drug Cerucal

Occasionally, mainly with higher doses of metoclopramide, patients may experience fatigue, headache, dizziness, fear, anxiety, and diarrhea.
In some cases, mainly in children, dyskinetic syndrome (involuntary tic-like twitching of the muscles of the face, neck or shoulders) may develop.
After discontinuation of the drug, these phenomena are weakened after a few hours; their immediate elimination by intravenous injection of biperiden is possible (the manufacturer's recommendations should be observed). For a sedative effect, the introduction of diazepam is indicated.
After prolonged treatment with metoclopramide, some elderly patients developed parkinsonism (tremor, muscle twitching, limited mobility) and tardive dyskinesias.
After more prolonged use of the drug, occasionally, due to the stimulation of prolactin secretion, gynecomastia in men, galactorrhea or a disorder may occur. menstrual cycle; with the development of these phenomena, the reception of metoclopramide is stopped.
In adolescents and patients with severely impaired renal function, the appearance of side effects, and with their development, the drug is immediately stopped.

Special instructions for the use of the drug Cerucal

Influence on the ability to drive vehicles.
Even when taken in accordance with the recommendations, metoclopramide can significantly impair the reaction rate and the ability to drive vehicles or work with potentially dangerous machinery. This effect is especially pronounced with the simultaneous use of alcohol.
In connection with the content of sodium sulfite in the injection solution Cerucal, in some cases, mainly in patients with asthma, hypersensitivity reactions to the drug may occur, which are manifested by nausea, diarrhea, shortness of breath, an acute attack of asthma, impaired consciousness or anaphylactic shock. The severity of these reactions is purely individual, in some cases they can pose a threat to the patient's life.

Interactions of the drug Cerucal

Anticholinergics can weaken the effect of metoclopramide. Metoclopramide may interfere with the absorption of other medicines. On the one hand, there may be a slowdown in the absorption of digoxin and cimetidine, on the other hand, an acceleration in the absorption of antibiotics, paracetamol and alcohol.
In addition, metoclopramide may enhance the effects of alcohol and sedatives. In order to prevent a possible increase in the severity of extrapyramidal disorders, antipsychotics should not be prescribed simultaneously with metoclopramide.
Metoclopramide may interfere with the action of tricyclic antidepressants, MAO inhibitors, and sympathomimetic agents.
Due to the content of sodium sulfite in the injection solution, thiamine (vitamin B1), taken simultaneously with Cerucal, can be quickly broken down in the body.

Overdose of the drug Cerucal, symptoms and treatment

Symptoms: drowsiness, confusion, irritability, motor restlessness, convulsions, extrapyramidal movement disorders, dysfunction of the cardiovascular system with bradycardia and an increase or decrease in blood pressure.
Treatment: with extrapyramidal disorders, biperiden is slowly administered intravenously. Control over the vital functions of the body is carried out until the symptoms of intoxication completely disappear.

Storage conditions of the drug Cerucal

Tablets: in a dark place at a temperature not exceeding 25 ° C.
Solution for injection: in a dark place at a temperature not exceeding 30 ° C.
The finished infusion solution can be stored at room temperature for 24 hours.
The ampoules taken from the packaging should not be left in sunlight for a long time.

List of pharmacies where you can buy Cerucal:

• St. Petersburg

Complete instruction - Cerucal

The main purpose of this drug is to resist the gag reflex and stimulate the digestive tract. One of the components of the drug is metoclopramide, which has an active effect, selectively blocking receptors and suppressing impulses to the brain from the esophagus. Also, cerucal reduces the sensitivity of visceral signals from nerve cells, which cause the gag reflex.

Pharmacological action of cerucal

Metoclopramide acts on the smooth muscles of the digestive tract, stimulating their work. Increasing tone allows you to work faster digestive system and naturally remove waste products.

With the help of the drug Cerucal, prevention of the occurrence of reflux and gastrostasis is also provided. Such an effect is a consequence of the normalization of bile secretion, as well as a decrease in the symptoms of biliary dyskinesia.

The antiemetic agent Cerucal will not be effective in all cases of disease. If the gag reflex is caused due to disruption of the vestibular apparatus or a psychogenic factor, then its action will have minimal effectiveness.

The two main forms of release of cerucal are tablets and an injection solution. The choice of the method of application lies entirely with the specialist who chooses the most effective method of treatment based on the history of the disease and the age group of the patient.

Oral administration of cerucal allows you to completely remove the substance from the body using the digestive system. The largest amount of the active substance of the drug is concentrated in the plasma within an hour after ingestion, and the beginning of the therapeutic effect will be carried out in half an hour. Activity with internal injections will be achieved within a few minutes after the injection.

When breastfeeding, the active substance of the drug will also be present in milk. Accordingly, the reception of cerucal in such a situation should be controlled by a specialist.

Cerucal tablets

One package of Cerucal contains 50 tablets. The calculation of the drug for children from the age of three is based on the patient's weight and is 0.1 milligram for each kilogram. From the age of 14, a one-time intake increases to 10 milligrams with a three-time course.

The individual dosage will be carried out in accordance with the characteristics of the organism of a particular patient. The greatest care should be taken with pathologies and disorders of the kidneys. In this case, you can also replace the drug with an alternative.

During the course of treatment with the use of the cerculus, alcohol should be excluded. The drug itself is taken shortly before meals, and in tablet form it can be taken with a little water. It is not recommended to drink it with milk, coffee or tea due to a decrease in the effectiveness of the drug. In the case of using activated carbon, the spread between doses of drugs should be at least 1-1.5 hours.

Cerucal injections, injections

Cerucal packaging contains 10 ampoules of two milliliters of solution each. Intravenous administration of the drug is carried out slowly or intramuscular injection is used. Intravenous administration is carried out from the age of 14 and no more than four injections per day.

Drip infusion of the drug is carried out for 15 minutes. Such a reception of cerucal is relevant in the complex treatment of cytostatic drugs.

Cerucal - indications for use

The main indication for taking this drug will be a disruption in the functioning of the digestive system and, in particular, the work of the muscles of the esophagus. Also, medication may be prescribed to relieve heartburn and irritated bowels.

The use of cerucal is relevant in case of liver or kidney dysfunction, removal of the consequences of head injuries and the gag reflex in the postoperative period. Taking the drug for diabetes will be effective if it is necessary to cure intestinal paresis. Cerukal provides high-quality research of the gastrointestinal tract and fluoroscopy.

Cerucal application

Injection use Cerucala is administered intramuscularly or by slow intravenous injection. Adolescents and adults can take this drug up to 3-4 times a day by intravenous infusion or intramuscular injections... The daily dose is no more than 10 milligrams for a single dose and about 25-30 milligrams for a daily dose.

When using cytostatic drugs, this drug should be taken in combination throughout the entire course of treatment. For intravenous injections, the drug cannot be used in a mixture with alkaline solutions.

Cerucal for children - features of the use of the drug in pediatrics

Taking the drug is prescribed from the age of three, before that its use will be negative. From the age of 14, this drug is taken in the same dosages as in adults. However, you should carefully follow the appointment and do not exceed the indicated amount of medication for administration.

For adolescents and adults, medication may be prescribed to relieve the gag reflex and eliminate feelings of nausea. Also, this remedy is relevant for the manifestation of similar symptoms after taking cytostatics, quickly and effectively affecting the body.

Starting from the age of three, taking the drug can be prescribed both in tablet form and as an injection. Cerucal tablets are taken shortly before meals, and the duration of treatment is from one month to six months.

Cerucal - use during pregnancy

In case of pregnancy, any drug must be agreed with a specialist who determines the need for taking it. Accordingly, it is undesirable to take cerucal in the first three months of pregnancy and after childbirth (during the feeding period) due to the ingress of the active substance into milk.

Alternative medications are prescribed for the first trimester, and cerucal can be used in the second and third trimester if it does more benefit than harm. In addition, even with the appointment of this agent, it is impossible to exceed the dosage indicated by the specialist or change the time of admission, which can have a negative effect on both the patient herself and the developing fetus.

Side effects of taking cerucal

Among the side effects of taking this drug are allergic reactions and the impact not only on the digestive system, but also on other body systems. Such an effect can lead to hypertension, migraine headaches, fatigue, dizziness, dryness in oral cavity, hormonal disorders, skin rash and other symptoms.

Side effects are most common in adolescence and old age. Moreover, the drug most often causes such symptoms in the case of kidney disease.

Contraindications for taking cerucal

The effect of the main component of the drug - metoclopramide, with weakening internal organs and against the background of other diseases will require the exclusion of the drug in the event of:

1 individual intolerance;

2 obstruction of the digestive system;

3 pheochromocytomas;

4 asthma with bronchial character;

5 epilepsy and seizures;

6 prolactin-dependent tumors;

7 gastrointestinal bleeding and bowel perforation;

8 Also, the drug cannot be prescribed in case of impaired renal function.

Complex reception, overdose and storage of cerucal

Taking the drug in combination with other drugs will lead to a change in the rate of absorption. This situation occurs due to an increase in the absorption of ethanol, antibiotics and paracetamol, as well as a decrease in the rate of excretion of digoxin and cimetidine from the body.

The use of cerucal in conjunction with antipsychotics, alcohol and sedatives is prohibited. The effect of tranquilizers, antidepressants and MAO inhibitors will change, which will require the exclusion of cerucal from the course of treatment or replacement of the drug. Overdose may cause drowsiness, seizures, change blood pressure and irritability.

For storing cerucal, a place protected from light with a temperature of 15 to 30 degrees is required. A solution for injection, ready to use, can be stored for no more than a day, and a drug in tablet form for up to five years.

Reviews about cerucale

Quickly dealt with nausea and vomiting after the appointment of cerucal. I am very pleased with its high efficiency.

As a result of gallbladder dyskinesia, for a long time I could not find a medicine. On the recommendation of a doctor, I tried cerucal and felt significant relief. Now I am taking the drug.

The pediatrician prescribed cerucal for the child, the result was encouraging, we will undergo the entire course of treatment.

evestart.ru

Cerucal - indications for use: it is necessary to establish the underlying disease

Cerucal is medicinal productwhich thanks to its medicinal properties, has become widespread in medical practice. This drug perfectly relieves nausea and vomiting of almost any origin and helps to restore the correct movement of food masses through the intestines.

The use of cerucal follows from the mechanism of its action

Cerucal is a centrally acting antiemetic drug that blocks the transmission of nerve impulses from the stomach and duodenum to the emetic center located in the brain.

As a result, the relaxation of the smooth muscles of the organs is suppressed. gastrointestinal tract, stomach contents enter the duodenum, and moves further through the intestines. Cerucal also prevents the return of food masses from the stomach to the esophagus and from the duodenum to the stomach. In addition, cerucal increases the motor activity of the biliary tract, which prevents stagnation of bile and diseases such as hypotonic biliary dyskenesia (that is, with reduced motor activity of the biliary tract muscles) and cholecystitis.

From the mechanism of action of cerucal on the smooth muscles of the gastrointestinal tract and biliary tract, its use in clinical practice.

For what diseases is cerucal used?

Vomiting and nausea can occur in a wide variety of conditions. They can accompany both diseases of the gastrointestinal tract and various severe diseases of other internal organs. Cerucal will help with nausea and vomiting of any origin, except for disorders of the vestibular apparatus.

In some cases, the smooth muscles of the stomach and intestines literally "refuse to work" and the feces do not move in the right direction. This condition is most typical for postoperative conditions, especially after operations on the abdominal cavity. In this case, Cerucal will help revive the work of smooth muscles and prevent serious complications associated with food stagnation in the intestines. At the same time, gases are also removed from the intestine, which greatly facilitates the patient's condition.

If the motor activity of the biliary tract is impaired (hypotonic biliary dyskinesia), cerucal will also help: it will make the smooth muscles of these organs contract and excrete bile into the intestines, thereby contributing to proper digestion.

In some diseases, food from the stomach goes back into the esophagus. And since it has already mixed with gastric juice, the acidic contents of the stomach constantly irritate the mucous membrane of the esophagus, causing its inflammation. This condition is called reflux esophagitis. Reception of cerucal brings relief to such patients, since it prevents the repeated throwing of food masses from the stomach into the esophagus.

Sometimes, as a result of diseases of the stomach and duodenum, functional (that is, transient) stenosis of the pylorus develops - the place of transition of the stomach into the duodenum. In this case, cerucal promotes the transfer of food masses from the stomach to the duodenum and their further movement through the intestines.

In diabetes mellitus, due to circulatory and innervation disorders, paresis of the smooth muscles of the stomach may begin and its contents cannot enter the duodenum. Cerucal solves this problem too.

Cerucal has found wide application in diagnostics. So, X-ray of the organs of the gastrointestinal tract is carried out using a contrast agent, which must move quickly enough through the stomach and intestines. Cerucal enhances peristaltic contractions of the intestine and promotes the advancement of contrast along it.

Cerucal is also successfully used with duodenal intubation - it helps to accelerate the emptying of the stomach and the movement of food through the small intestine, which means more rapid secretion of bile.

How to take cerucal correctly

The dose of the drug and the duration of the course of treatment is determined by the doctor depending on the disease, age and individual characteristics of the patient.

But there are also standard recommendations developed by cerucal manufacturers. Inside, cerucal is taken in tablets half an hour before meals 3 - 4 times a day in a dose individually selected by the doctor. The course of treatment is usually one to one and a half months, but sometimes it can be extended to six months.

When severe conditions patients with cerucal are administered intramuscularly or intravenously, but as soon as the patient's condition improves, they switch to taking the drug inside. In case of impaired renal function, cerucal may not be excreted from the body in full, therefore, such patients require a correction of the prescribed dose of the drug.

For children, the dose is calculated by the patient's weight and is also selected individually.

Galina Romanenko

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Cerucal tablets - indications, contraindications

Home »Treatment of gastritis» Cerucal tablets - indications, contraindications

Attention: the information is not intended for self-medication. We do not guarantee (although we strive to do so) its accuracy, reliability or relevance in your case. Treatment should be prescribed by a specialist doctor.

Cerucal is a fairly effective agent with a prokinetic and pronounced antiemetic effect, but this drug must be used with the greatest caution (it is no coincidence that it is recommended to be dispensed only by prescription).

Unfortunately, under certain circumstances, it can cause very serious side effects. What are the advantages and disadvantages of this medication should the patient know?

What can the drug be used for?

The main active ingredient of cerucal - metoclopromide hydrochloride - blocks dopamine and serotonin receptors. The neurotransmitters dopamine and serotonin are chemical factors that indirectly stimulate vomiting. As a result, the passage of unwanted impulses through the chemoreceptors of the brain is prevented.

The motility of the gastrointestinal tract is normalized. At the same time, bile secretion is corrected, there is a beneficial effect on the muscle tone of the intestines.

The medicine is available in the form of flat white tablets, as well as a composition for injection in ampoules.

Indications for use:

How to drink cerucal in tablets: rules for taking

The duration of the course is from several weeks to six months (with a normal reaction to the drug).

The optimal time for taking is half an hour before meals. The dosage is individual. Adults and children at least 14 years of age are most often recommended to drink one tablet (10 mg) three to four times a day. For small children, the dose is selected taking into account body weight at the rate of 0.1 mg. per 1 kg., the maximum daily intake is half a milligram per kilogram of weight.

In case of an overdose, lethargy or, conversely, anxiety, confusion, dizziness occurs. With a significant deviation from the instructions, even convulsions are possible.

We list the main contraindications:

1. gastrointestinal bleeding;
2. perforation of the ulcer;
3. asthma;
4. arterial hypertension;
5. epilepsy;
6. pregnancy (the prohibition is categorical, since there is a risk of fetal malformations);
7. period of breastfeeding;
8. age up to two years;
9. pheochromocytoma;
10. hypersensitivity to metoclopramide and sodium sulfite.

Be sure to check with your doctor or at least a pharmacist if cerucal works well with other medications you are taking. The drug is very specific, it can significantly enhance or weaken the effect of many medicines. We will not present a long list here.

With regular intake of cerucal, at first, it is advisable not to engage in work that requires instant psychomotor reactions - in particular, not to drive a car.

Side effects

The most significant possible (albeit unlikely) deviations from the central nervous system are drowsiness, agitation, mood swings from euphoria to groundless depression, speech disorders, spasms of the facial muscles. An elderly person with long-term treatment with metoclopramide can develop parkinsonism.

From the digestive tract, constipation or diarrhea, discomfort in the mouth are likely.

Endocrine and cardiovascular disorders, menstrual irregularities are not excluded.

How to treat gastritis drugs for gastritis

gastrit-yazva.ru

Cerucal instruction

Cerucal is an adjuvant that improves motility and the functioning of the stomach and intestines, produces an antiemetic effect. It is also used for a quick effect on the stomach and intestines, and their emptying due to the stimulation of the muscles.

Cerucal general information

Substances that are part of cerucal, as auxiliary: sodium sulfite, chloride, distilled water. The drug can be purchased both in tablets and as an injection.

Cerucal tablets

Cerucal tablets, white, round in shape, 4-5 mm in height, 6-7 mm in radius, with the passage of the strip in the center, the surface is smooth with even flat edges. One tablet contains metoclopramide hydrochloride monohydrate - 10.54 mg, which is identical to 10 mg of anhydrous metoclopramide hydrochloride. The tablet contains: gelatin base, silicon dioxide, starch, lactose. The package consists of 50 tablets.

Cerucal injections

Cerucal for injection is a clear, colorless solution. 1 injection consists of a 2 mg ampoule, which contains 10 mg metoclopramide hydrochloride, sodium sulfite, disodium salt, distilled water, carbon dioxide. The package of Cerucal for injection contains 10 ampoules of 2 mg each, protected by special durable cells.

Pharmacology

Cerucal is a drug that is used for disorders of the gastrointestinal tract in the upper sections, for stomach irritation syndrome, severe heartburn. The remedy is especially effective for various vomiting reflexes caused by different kinds irritants, for example, in liver diseases, head injuries, severe migraines. The use of the substance helps to regulate the tone of the stomach and intestines, improves the muscles, and this helps to accelerate the emptying of the stomach, improves intestinal peristalsis. The drug is used when examining the intestines, duodenum, small intestine, namely when an umbrella is inserted, to accelerate the cleaning of the stomach and push food masses through the small intestine, when examining diseases of the stomach and small intestine.

Indications for cerucal

It is recommended to use the drug for: strong gag reflexes, of various origins, in postoperative period (operations on the stomach and intestines), the ingress of bile into the stomach, with diseases of the liver and kidneys, with internal examinations of the X-ray apparatus of the intestines and stomach, with severe constipation, to improve the movement of food in the jejunum from the stomach, with mechanical damage in the head area, with diabetes mellitus.

Contraindications

Cerucal is prohibited for use in case of: special sensitivity of a person to the drug, mechanical blockage of the intestinal lumen, with severe gastrointestinal bleeding, with tumors, it is not recommended for patients experiencing epileptic spasms and having movement disorders, in the first months of pregnancy, breastfeeding of a child, the use of the drug is prohibited for children under 2 years of age, use is not recommended for bronchial asthma and people with allergies. For people suffering from low blood pressure, women who are at a later stage of pregnancy, patients with renal insufficiency, children aged 3-14 years, the medicine can be used under the strict guidance of doctors and with accurate dosage.

Cerucal instructions for use

The dosage of the drug should be strictly observed. The doctor prescribes the dosage separately for each patient, it depends on the general condition of the patient and age qualities. For adults and adolescents under 14 years of age, it is recommended to use 10 mg of metoclopramide at a time, but the dosage per day should not exceed 30-40 metoclopramide. In tablets - these are 3-4 tablets per day, in injections - 3-4 injections per day. For children under 14 years old, the dosage is calculated on the basis of 0.1 mg per body weight, it is the same for both injections and for the use of tablets inside, be careful the dosage should not exceed 0.5 mg per 1 kg per day. The drug is used 25 minutes before meals, if in tablets. With creatinine clearance, the dose of metoclopramide should be 10 mg once a day from 10 to 55 ml / min 10 mg once a day and 4.5 mg once a day. Prescribing the drug in an increased dosage for nausea and vomiting, due to cytostatic agents: you can use a short infusion dropper (no more than 15 minutes). Cerucal is administered at a dosage of 2 mg / kg 30 minutes before the start of treatment with a cytostatic agent, then the frequency changes by 1 time in 2 hours, 2 times in 31 hours, after using the drug. When using drip infusion for a longer period, Cerucal is administered at a dose of (0.5) mg / kg per hour, 2 hours before the start of the use of cytostatic agents, after the first time, the next dose is 0.5) mg / kg per hour and so on during the day , only after the use of cytostatic agents. The period of treatment is determined by the doctor. The frequency of one course of treatment can last for 5 to 6 weeks. In difficult cases, treatment is carried out for up to 5 months, but no more.

Cerucal during pregnancy

It is strictly forbidden to use the drug for the first time months during pregnancy. In the following months, use is possible only under the supervision of a physician and in certain dosages. During lactation, if the use of the device is unavoidable, breast-feeding the child stops and is transferred to artificial nutrition.

Side effects

With prolonged use of the drug, the patient may experience constant fatigue, frequent headaches, dizziness, an involuntary feeling of fear, anxiety, a tendency to depression, increased drowsiness, noisy sensations in the head, involuntary contractions of the muscles of the facial muscles, unclear speech. If the drug is used for a long time, a gynecomastia disease may occur, since the drug stimulates secretion, hormonal imbalance occurs in young girls and women, menstruation disorders occur, in rare cases, they may not be abundant, and most often severe bleeding opens, then the drug is prescribed canceled. If the drug is used for a long time by elderly patients, then Parkinson's disease can develop in parallel. In adolescence, long-term use of the drug may be due to kidney disease, then the drug is very slowly excreted from the body and there is every chance of developing symptoms in case of an overdose, in such cases it is necessary to monitor the child's condition, if deterioration is noticed, then the drug is not used. Due to the fact that sodium sulfite is present in the solution of Cerucal for injection, sometimes patients have allergic reactions, this is mainly inherent in people who are sick bronchial asthmacan be observed elevated temperature, diarrhea, nausea, cough, feeling short of breath, suffocation, loss of consciousness. Such reactions are individual, in some people they can lead to an immediate threat to their lives.

Special notes

Cerucal requires very careful use. Even if the drug is used correctly and exactly as prescribed by the doctor, the drug can provide different types actions, up to the fact that a person loses the ability to react quickly, for example, while driving a car or when servicing cars, a person may react slowly to pressing the brake or other different cases... The drug acts especially sharply on the reaction if it is taken simultaneously with alcoholic beverages. The drug is contraindicated for those who are driving and for those who work in a dangerous enterprise.

Overdose symptoms

In case of an overdose, severe drowsiness, loss of consciousness, irritation, involuntary convulsions, delirium, cardiovascular dystonia, hypertension, headaches may occur. If the form of poisoning is mild, then the symptoms disappear after 24 hours. In case of poisoning, the patient should be observed until the symptoms disappear completely. Lethal outcomes were not registered. Diazepam is used to completely calm the patient. The dosage for adults ranges from 3-5 mg, for children - 0.05 mg / kg of body weight.

Interaction with other drugs

The effect of the drug can greatly reduce the effect of anticholinergics. Under the influence on the dynamics of the stomach and intestines, the drug can change the absorption of other drugs. In the best case, there may be slow absorption, in the worst case, it is good if there is an accelerated absorption of the necessary antibiotics and supporting drugs, and it is bad if paracetamol and alcohol are quickly absorbed. It is imperative to exclude the use of antipsychotic drugs with cerucal. If you do not adhere to these recommendations, then the drug can cause irreparable harm to the human nervous system. In the case of using a vitamin that supports immunity together with the drug, you should pay attention that some vitamins are capable of disintegrating when interacting with the drug.

Pharmaceutical interaction: if you mix vitamin B1 with Cerucal, then vitamin B1 will lose its properties.

Cerucal for children

Cerucal can act in very different ways on the child's body, so its use should be agreed with the observing doctor. The drug has blocking abilities, nerve impulses on the way from the stomach to the duodenum are blocked and do not enter the nervous system, and the central nervous system does not respond to signals, which leads to nausea, vomiting and constipation. The child may also develop high fatigue, headache, seizures, unreasonable fear, muscle contractions of the esophagus, and subsequently severe spasms, heart palpitations. An adult's body is much more resistant to side effects than a child's body. In a child, side effects appear in the stomach and intestines, it may be a feeling of discomfort, the effects of the drug on each child can have a different effect, it all depends on the child's age, the younger the child, the more side effects may appear brighter. The use of the drug by children under 2 years of age is strictly prohibited. After two years, the drug can be prescribed to a child, only under the supervision of a doctor and if the use of this drug is unavoidable.

Side effects that may occur in children when using cerucal

In children, the children's nervous system is especially susceptible to the effects of the drug. It is worth paying attention to the fact that at the age of 14 and older, the side effects listed above may be rare. This is explained by the fact that in an adult, the gastrointestinal tract is exposed to the drug. For young children, the list of side effects is quite huge, and very different. In children, the central nervous system is affected. After observing a child, you can notice changes in his behavior. He will be lethargic, sleepy, restless, anxious, complaining about headache, speech disorders, tremors in hands and feet, unreasonable outbursts of rage and irritability are possible. The use of the drug is also dangerous because the child develops a decrease in leukocytes, and this also leads to a decrease in general immunity. All chronic diseases begin to appear sharply, which, due to weak immunity, are subject to long-term treatment. As for the stomach and intestines, constant constipation appears, or, on the contrary, diarrhea with dehydration of the body. Particular attention should be paid to the use of the drug in adolescence, girls may experience a hormonal failure, which in the future may affect the state of women's health, in boys with hormonal failure, the mammary glands may enlarge, like in women.

In what cases children should not be prescribed cerucal

The drug is completely contraindicated for children under 2 years of age. Do not use the drug if adolescents have problems with renal failure. It is not prescribed for children with bleeding in the intestines, epilepsy, hypertension, bronchial asthma. A doctor should prescribe this medicine, you can get advice and an individual dosage only from a specialist. It is forbidden to use cerucal by a child without a prescription from a doctor. The drug must be stored in a dark place. The shelf life of tablets is 24 months from the date of release. It is better to inject a ready-made solution for injection immediately, if required, it can be stored at a temperature of +15 degrees for 20 hours. And remember, self-medication can harm your health.

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Instructions for use:

Cerucal is an antiemetic drug that blocks dopamine receptors, presented in two dosage forms:

• The tablets are round, flat, white, with beveled edges. 1 tablet contains 10.54 mg metoclopramide hydrochloride monohydrate (active substance) and auxiliary components (potato starch, lactose monohydrate, magnesium stearate, gelatin, precipitated silicon dioxide);
• Solution for intramuscular and intravenous administration. 1 ampoule of the drug contains 10 mg metoclopramide hydrochloride - active ingredient - and excipients: sodium chloride, sodium sulfite, disodium EDTA, water for injection.

Pharmacological action of Cerucal

According to the instructions for Cerucal, the drug has an antiemetic effect, normalizing the functioning of the digestive tract. Metoclopramide, the main active component of the drug, selectively blocks serotonin and dopamine receptors, preventing the passage of impulses through the receptors in the brain and reducing the sensitivity of nerve cells responsible for the transmission of impulses from the duodenum to the vomiting center located in the medulla oblongata. Due to the effect of the drug on the work of the autonomic nervous system, Cerucal restores the motility of the upper gastrointestinal tract. Under the influence of Cerucal, the tone of the smooth muscles of the intestinal and stomach walls returns to normal, as a result of which the time for evacuation of the digested food into the duodenum decreases, and the peristalsis of the small intestine improves. In addition, Cerucal promotes normal bile flow, reducing the symptoms of gallbladder dyskinesia and preventing the appearance of cholestatic jaundice. According to the instructions for Cerucal, the active substance of the drug has a direct effect on the sphincter of Oddi, reducing the manifestations of its spasm.

Despite the antiemetic effect of the drug, Cerucal, according to patients' reviews, is not able to exert a therapeutic effect on vomiting of a vestibular and psychogenic nature.

After oral administration, Cerucal is almost completely absorbed from the gastrointestinal tract, reaching a maximum concentration of metoclopramide in the blood within an hour. The main therapeutic effect of the drug lasts for 12 hours. Cerucal metabolism occurs in the liver. The drug is excreted in the urine: unchanged, and also in the form of metabolites.

After intramuscular or intravenous administration healing effect Cerucala reaches its maximum after 10-15 minutes and 1-3 minutes respectively.

Indications for the use of Cerucal

Indications for Cerucal are conditions associated with impaired activity of the digestive tract, including: heartburn, irritable bowel syndrome, functional pyloric stenosis. The effectiveness of the drug also extends to nausea and vomiting of various origins (caused by medication, impaired liver and kidney function, migraine, craniocerebral trauma), gastric paresis, which developed due to diabetes mellitus. In addition, Cerucal is used as a means of reducing vomiting during diagnostic studies of the gastrointestinal tract (in particular, duodenal intubation).

Contraindications

• Pheochromocytoma;
• Intestinal obstruction;
• Bleeding from the gastrointestinal tract;
• Gastrointestinal perforation;
• The presence of a prolactin-dependent tumor;
• Epilepsy and convulsive seizures.

The drug is not prescribed in the presence of hypersensitivity to metoclopramide and sodium sulfite, especially to patients suffering from bronchial asthma and other allergic diseases... Cerucal is not intended for use by pregnant women in the first trimester of pregnancy, as well as children under 3 years of age. In the second and third trimesters of pregnancy, the use of the drug is possible only in case of vital indications. According to indications, Cerucal is taken with caution by patients with arterial hypertension, bronchial asthma, people suffering from impaired liver function, hypersensitivity to procainamide and procaine.

Side effects of Cerucal

According to reviews of Cerucal, the use of the drug can provoke the following side effects:

• From the side of the central nervous system: dizziness, tinnitus, headache, increased fatigue, fear, depression, anxiety;
• From the side of the cardiovascular system: tachycardia, agranulocytosis, changes in blood pressure;
• From the gastrointestinal tract: dry mouth, stool disturbance, change in taste;
• On the part of the endocrine system, unwanted symptoms can manifest itself as a change in the amount of estrogen, accompanied by menstrual irregularities and gynecomastia;
• Allergic reactions: urticaria, pruritus.

In case of an overdose of the drug, irritability, confusion, convulsions, hyperkinesis, bradycardia, extrapyramidal movement disorders, an increase or decrease in blood pressure are possible. According to reviews to Cerucal, the symptoms of mild poisoning disappear 24 hours after the drug is discontinued. For more severe disorders, symptomatic treatment is recommended.

Interaction of Cerucal with drugs

Metoclopramide, when used simultaneously with other drugs, reduces the absorption of cimetidine and digoxin and accelerates the absorption of antibiotics, ethanol and paracetamol. The effectiveness of Cerucal when taken simultaneously with anticholinergics is reduced. The introduction of an injection solution of the drug promotes more rapid breakdown of vitamin B1 - thiamine.

This instruction to Cerucal is presented for informational purposes only. Consult a physician before using this medicine.

Vomiting is an involuntary reaction of the body, often associated with the multiplication of pathogenic microorganisms, with the intake of low-quality products. Discharge of vomit is defensive reaction organism. An effective result will only bring a complex treatment, including the intake of enterosorbents, rehydration drugs, prebiotics and, if necessary, antibiotics, antispasmodics, antipyretics. Besides, therapeutic measures with vomiting, it is assumed that the drinking regime and diet are followed.

If a child starts to vomit, first of all, you need to take care of the correct position of his body: you cannot throw your head back, put the child on his back, in this case, vomit can enter the respiratory tract. You need to lay the baby on one side and raise his head a little. Then immediately call an ambulance.

The first procedures at home are gastric lavage boiled water... Further treatment should be carried out according to the doctor's instructions.

Of the drugs, the intake of Cerucal is often prescribed - a medicine for vomiting, allowed for children from 2 years old.

Cerucal is a common medicine for nausea and vomiting approved for children. The drug enhances the motility of smooth muscle tissues of the digestive system and blocks the transmission of signals from the nervous system going from the small intestine and stomach to medulla oblongata - the center that activates the gag reflex.

Thanks to this mechanism, the brain “does not know” about the disorder of smooth muscles and does not cause such processes as vomiting, nausea, hiccups, and constipation.

Cerucal is available in pill and injection form. It is impossible to independently make a decision about taking it, since the drug has many side effects, and there is a high risk of choosing the wrong dosage. Indications for use are diseases of the gastrointestinal tract with indomitable vomiting.

Illnesses with frequent or non-stop vomiting can quickly lead to dehydration and loss of important micronutrients. At the same time, the child noticeably loses weight, there is a risk of developing a state of shock.

In such situations, despite the possible complications, Cerucal is the only effective remedy for vomiting in children. It is better if the drug is taken under the supervision of a doctor, for example, in a hospital.

• for children from 2 to 14 years old, it is 0.1 mg of metoclopramide per kilogram of body weight, while the daily dose should not exceed 0.5 mg of the active substance per 1 kg of body weight. That is, in the maximum dosage, the drug can be used no more than 5 times a day. If there are kidney diseases, the permitted amount of the drug is determined by the doctor individually;
• for children from 14 years of age, the dosage of the drug can be increased to 10 mg, taken 3 times a day. The tablets are taken half an hour before meals. The full course of treatment is 4 to 6 weeks. At the discretion of the doctor, its duration can be shortened or increased.

Indications and contraindications

Since the main mechanism of action of Cerucal is associated with the stimulation of the smooth muscle motility of internal organs, it is prescribed exclusively for diseases of the digestive tract.

The indications include the following conditions:

• nausea and vomiting, except when caused by signals from the vestibular apparatus ();
• disorders of the motor function of the gastrointestinal tract, for example, biliary dyskinesia;
• violation of the motor activity of the stomach (paresis) due to diabetes mellitus;
• preparation for diagnostic procedures of the gastrointestinal tract.

The list of contraindications for taking Cerucal includes:

• the presence of pheochromocytoma (a tumor that synthesizes adrenaline in large quantities);
• various disorders of the intestine, including its obstruction;
• the presence of prolactin-dependent tumors;
• disturbances in the structure of the walls of the stomach, duodenum;
• bleeding in the stomach, esophagus, small or large intestine;
• individual intolerance;
• a history of convulsions;
• nervous tics in the facial muscles;
• the first three months of pregnancy;
• breastfeeding the baby;
• children's age from birth to 2 years.

Most often, Cerucal is used for nausea and vomiting in a child. It is important to remember that only a doctor can prescribe it, since for a successful recovery it is necessary to find out the cause of the symptoms.

Adverse reactions

Side effects from taking Cerucal are largely determined by the age of the patient. In children, most of these manifestations are associated with the effect of active substances on the central and peripheral parts of the nervous system.

IN childhood the use of Cerucal can cause emotional and psychological disorders: phobic manifestations, anxiety, anxiety, low and gloomy mood.

Possible neurological symptoms include headaches, lethargy, drowsiness, dizziness, tics in the muscles of the neck, face and shoulders, speech impairment, and tremors.

According to medical practice, most often in children, as a side reaction, dyskinetic syndrome manifests itself, when uncontrolled movements of the muscles of the face and neck appear. And although this condition is not life-threatening, it can negatively affect a child's adaptation in school or kindergarten. It is for this reason that Cerucal is prescribed to children carefully, under the supervision of a doctor. On manifestation adverse reactions treatment is interrupted.

Alternative remedies for vomiting

Despite its effectiveness, Cerucal has many side reactions and contraindications, one of which is age up to 2 years. The drug is always prescribed with caution and under close medical supervision. It is extremely rarely used in infants, if possible, it is replaced with other drugs.

Motilium can serve as an alternative to Cerucalus. This medicine for nausea and vomiting is allowed for children from one year old, and with careful control - from birth. It is produced in the form of a suspension, which greatly simplifies the procedure for taking in babies.

Indications for use, in addition to nausea and vomiting, are: belching, flatulence, heartburn, abdominal discomfort (bloating, feeling overcrowded, pain), dyspepsia. Before use, you should carefully study the instructions for the drug, since it also has contraindications and side effects.

But-spasm it is used for vomiting caused by functional spasms, acute gastroenteritis, febrile syndrome, increased intracranial pressure and consequences radiation therapy.

Also used for abdominal pain, with symptomatic therapy organic diseases gastrointestinal tract. Allowed for admission to children from the first days of life. Available in the form of syrup and solution.

Traditional methods of treating vomiting

To completely cure the disease, you need a complete diagnostic examination and treatment according to the doctor's recommendations. But folk remedies from nausea and vomiting in children, the condition can be significantly improved. In addition, these methods can be successfully used as part of complex therapy.

The following plants will help you quickly stop an attack of vomiting:

1. Peppermint. It is necessary to prepare a decoction on its basis: 1 tbsp. l. leaves pour a glass of boiling water, insist for 2-3 hours in a thermos. Then filter and take a tablespoon three times a day as soon as nausea appears.
2. Melissa ... The broth is prepared as follows: 1 tbsp. l. herbs are poured with a glass of boiling water, boiled for 2 minutes. The filtered liquid helps not only against vomiting, but also against nausea, disruption of the stomach.
3. Dill seed ... For the broth, you need to take 1 tsp. dill seeds, pour them with a glass of hot water, simmer over low heat for 13-15 minutes. Filter and drink three times a day for 2 tsp.
4. Valerian root ... Grind the root and 1 tsp. pour a glass of hot water into the powder. Boil for about 10 minutes, filter. Take 1 tsp. 3 times a day.
5. A mixture of medicinal herbs : peppermint leaves, chamomile flowers, lemon balm flowers and leaves. All herbs must be taken in the same amount, chopped and mixed well. Then 1 tbsp. l. Pour boiling water over the resulting powder. Cover the container and leave for 30 minutes. Filter the broth, drink 1 tbsp three times a day. l.

All these recipes will not help if the baby Then you need to call an ambulance as soon as possible.

Traditional methods - first aid before the arrival of a doctor or in case of a single vomiting, not accompanied by other symptoms (abdominal pain, fever, diarrhea, etc.). In other cases, it is impossible to get involved in self-medication. Skilled specialist care cannot be replaced by home procedures.

Useful video about the causes of vomiting in a child

Vomiting is a natural reaction of the body to the intake of harmful substances or pathogenic microorganisms.... With the help of the gag reflex, the body cleans itself. But sometimes vomiting becomes uncontrollable and can lead to dehydration. This condition is dangerous for people of any age, but small children who are of low weight are especially affected. With severe vomiting, doctors prescribe various antiemetic drugs, one of which is cerucal. Instructions for the use of cerucal for vomiting for children prescribes that it is allowed to use it even in children from 2 years of age, but only as directed by a pediatrician or infectious disease specialist.

Why does vomiting occur in children?

Vomiting in children is for various reasons. But in any case, the baby needs help quickly to prevent dehydration... The main causes of vomiting can be distinguished as follows:

• Poisoning by poor quality food, drugs or other toxic substances.
• Diseases of the gastrointestinal tract of an infectious nature.
• Congenital malformations of the digestive organs or chronic diseases stomach and intestines.
• Weakness of the vestibular apparatus, which is accompanied by severe motion sickness in any transport.
• Binge eating.
• Excessive nervous tension.

Vomiting can also be triggered by an allergy to a particular food product.... Basically, this condition is first manifested by hiccups and skin rashes, and then vomiting is added.

General characteristics of the drug

Cerucal is one of the common antiemetic drugs that can be used for nausea and vomiting in children. The active ingredient is metoclopramide. The medication helps to increase the motility of the digestive organs and stops the flow of signals between the nerve endings of the stomach and intestines to the brain, which is considered the center that activates the gag reflex. It is thanks to this that signals about digestive upset do not reach the brain and nausea and vomiting do not occur.

The pharmaceutical industry produces Cerucal tablets for nausea and injection. It is impossible to self-medicate, since the drug has many side effects, and the dosage can be chosen incorrectly. A drug is prescribed for disorders of the digestive system, which are manifested by profuse vomiting.

Diseases in children, which are accompanied by severe vomiting, lead to severe dehydration in a matter of hours. In such cases, the only way out is cerucal, which it is advisable to use under the supervision of a doctor.

What is the dose of cerucal given to children

The dosage of the drug is calculated based on the child's body weight and the severity of the condition... In exceptional cases, the dose may be slightly increased, but this decision is made only by the attending physician:

• Children from 2 to 14 years old are prescribed a drug in a dosage of 0.1 mg of active ingredient per 1 kg of body weight, but the daily rate should not be more than 0.5 mg of metoclopramide per 1 kg of body weight. If the patient has chronic kidney disease, then the volume of the drug is calculated by the doctor on an individual basis.
• Children over 14 years of age are allowed to increase the dose of the drug to 10 mg, they drink cerucal 3 times a day. The tablets are drunk 30 minutes before meals with plenty of clean water. The full course of therapy is often up to one and a half months. The doctor can adjust the course of treatment based on the test data and the general condition of the child.

Cerucal in ampoules for children with vomiting is prescribed in cases where vomiting, nausea or hiccups must be stopped quickly. Injections for nausea and vomiting in adolescents from 14-18 years old are given intramuscularly, at the rate of 1 ampoule up to three times a day. The dosage for injections for a child under 14 years old is calculated by the doctor, based on the weight of the small patient.

Cerucal cannot be stored in open ampoules. They are opened immediately before use, while observing all the rules of antiseptics. Store the medicine package in a cool, dark place out of the reach of children.

Indications for the use of the medication

Cerucal acts on the motility of the digestive organs, therefore it is prescribed for any disorders that are accompanied by persistent nausea and vomiting... It is indicated for such diseases and conditions:

1. With severe nausea and indomitable vomiting, in addition to cases when this condition is associated with weakness of the vestibular apparatus.
2. In case of impaired motility of the gastrointestinal tract, for example, with dyskenesia of the bile ducts.
3. With paresis of the stomach due to diabetes mellitus.
4. In preparation for diagnostic manipulations on the digestive organs.

Besides, prescribe cerucal in tablets to children with vomiting, when it is impossible to stop it by other means... Usually this drug is used in a medical facility, but according to the doctor's indications, therapy at home is also possible if the child is over 7 years old.

Contraindications to use and side effects

In young children and adolescents, taking cerucal is limited by a number of contraindications, which must be taken into account when choosing a drug. These include the following diseases:

• benign and malignant tumors that produce adrenaline in large volumes;
• chronic and acute bowel diseases, including obstruction;
• prolactin-dependent tumors;
• a history of epilepsy;
• congenital anomalies in the structure of the intestines and duodenum;
• suspicion of bleeding in the digestive organs;
• individual intolerance to the substances that make up the medication;
• convulsions and nervous tics of the face;
• children under 2 years of age.

In special cases, cerucal is also prescribed for children under 2 years old, after weighing all the risks. In this case, the attending physician calculates the dosage, based on age, weight and general state sick child.

Cerucal has a lot of side effects that do not depend on the form of the medicine. Most often, such changes in health are manifested:

• On the part of the nervous system, there may be increased fatigue, dizziness and tinnitus. Also often there are complaints about nervous tic in children, which occurs when taking the drug.
• On the part of the blood supply system, changes occur in the composition of the blood - the level of granulocytes, an important component of leukocytes, decreases.
• On the part of the digestive system, there may be constipation or, conversely, diarrhea, as well as severe dryness of the oral mucosa.
• From the side of the cardiovascular system, surges in blood pressure and increased heart rate are possible.
• On the part of the endocrine system, breast enlargement in boys and cycle failure in adolescent girls is possible.
• From the side immune system there may be allergies in the form of skin rashes and asthmatic attacks.

If any side effects appear while taking the drug, they stop drinking it and contact the attending physician for adjusting the treatment.

How to take cerucal for poisoning

If a child is poisoned by poor-quality food or drugs, then through vomiting the body is cleansed and recovery occurs faster. In such cases, antiemetics should not be given immediately after the first bouts of vomiting., this will slow down the output toxic substances in a natural way. To begin with, the child needs to provide first aid, which will be aimed at quickly removing toxic substances from the body. Protocol emergency care such:

1. The stomach is thoroughly washed with a large volume of water. You can take pure water or with the addition of potassium permanganate. Potassium permanganate is preliminarily dissolved in a small volume of water, and only then added to the total volume of water for washing.
2. Give any adsorbents in a therapeutic dose. If activated carbon is used, then it is preliminarily ground into powder and diluted in a small volume of water, and then only given to the child.
3. They make a cleansing enema, for which they take slightly salted water or a decoction of chamomile.

If all these activities did not help stop vomiting, then the use of antiemetic drugs, for example, cerucal, is indicated. In case of poisoning, Cerucal can be drunk only after consulting a doctor.

Injections from vomiting cerucal are prescribed only in severe cases, when the child cannot take pills due to vomiting. It is forbidden to prescribe and make injections on your own, as this can lead to an overdose and serious consequences.

Drug overdose

An overdose with cerucal can be in the case of self-medication or an incorrectly calculated dose, when the doctor determines the weight of a small patient by eye. Another reason for overdose is improper storage of medicines when they are stored in a place accessible to children. If the child has taken too many cerucal tablets, then it is necessary to urgently call a doctor or take the baby to the hospital on its own.

Overdose symptoms are quite specific, they can be distinguished by the following points:

• atypical drowsiness appears, confused consciousness;
• there is increased excitability and physical activity, which then develops into convulsions;
• the work of the heart is disrupted, which is manifested by the instability of blood pressure, palpitations and high pulse.

If extrapyramidal disorders are observed with an overdose, then slow intravenous administration of an antidote is shown, which is biperiden. In this case, the child should be under constant medical supervision until all signs of an overdose disappear completely.

How to prevent overdose

To avoid poisoning with cerucal, it is enough to follow a number of simple rules:

1. Do not self-medicate, following the advice of relatives or neighbors. Any medications can only be taken if prescribed by a doctor.
2. Do not leave medicines where children can reach. All medicines should be kept in a special medicine cabinet or a lockable box.
3. Cerucal in ampoules is prescribed only by a doctor. The medicine can be injected only after 6-8 hours, during this period of time the previous dose is almost completely excreted from the body.
4. You cannot take an expired drug. Active substance in such medicines it decomposes and forms toxic elements.

Even if a doctor prescribes cerucal for treatment, it is necessary to accurately inform him of the patient's weight. With a correctly calculated therapeutic dose, an overdose is excluded.

Drug analogs

Instead of cerucal, your doctor may prescribe other antiemetic drugs for children that have a similar effect. Despite the fact that cerucal is a highly effective antiemetic agent, it has a lot of contraindications and side effects, therefore, if possible, it is changed to other medicines:

• Motilium is an excellent replacement for cerucal, especially since it is allowed to be prescribed to children from 1 year old, but with constant supervision of a pediatrician and from birth. This remedy for nausea and vomiting for babies is sold in the form of a suspension with a pleasant taste, which makes it easier to treat babies. Besides, motilium helps to get rid of flatulence, belching and feeling of fullness in the abdomen. It is sometimes prescribed to babies for intestinal colic;
• No-spasm - prescribed for vomiting, which is caused by functional disorders. This can be gastroenteritis, high intracranial pressure, or radiation therapy. This medication can be given to children from the first days of life, but only under the supervision of a doctor and in accordance with the calculated dosage. But-spasm can be purchased in the form of a syrup for babies and in the form of a solution for patients of the older age group.

All analogs have their limitations and side effects. Before starting admission, you must carefully study the annotation.

How else can you eliminate vomiting in a child?

When vomiting is caused by typical food poisoning and the child's condition is satisfactory, then you can do without antiemetic drugs. In this case, traditional medicine recipes can help. To stop vomiting attacks, children are given a decoction of peppermint or lemon balm... To prepare a medicinal broth, you need to pour a tablespoon of chopped leaves with a glass of boiling water and insist in a thermos for about two hours. Then filter the broth and give a tablespoon to drink every half hour, until the condition normalizes.

Drinking honey with lemon will not only replenish the fluid lost during vomiting, but also regulate the balance of electrolytes in the body. Such a delicious drink has a tonic effect and quickly removes vomiting. It is consumed often, but in small portions.

Before trying to stop vomiting, you need to understand what causes it.... If this is poisoning with toxic substances, then you should not immediately take cerucal, you need to wait until the body is a little cleansed of harmful substances.