Ximelin Extra - instruction, application, indications, contraindications, action, side effects, analogues, dosage, composition. Ximeline Extra Analogues and Prices of Ksimlin Analogues for the Active Substance
Like most other drugs, Ximelin has analogues that can be as much lower at a price or, on the contrary, a little higher. At the same time, it is very important to choose the right tool and not mistaken with quality.
Composition of the drug Ximeline
Most often with diseases of this type, like rhinitis, or Polynosis, the doctor appoints this nasal spray. It helps to narrow the blood vessels of the nasal mucosa and facilitates breathing. Sometimes this drug is prescribed to patients who have to have diagnostics (rososcopy). It includes:
- xylometazoline hydrochloride;
- hipratropy bromide monohydrate;
- excipients.
Due to its components, the Ksymelin nose components do not irritate the mucous membrane and act almost immediately. The effect of its application continues for 10-12 hours. Therefore, even if your breathing becomes more difficult, it is not necessary to irrigate the nose every two hours - this can lead to adverse consequences.
In principle, Ximelin is not addictive, if used according to the instructions, where doses and injection frequency are indicated. In any case, you should not use the preparation of a more recommended period. Although there are cases when patients are quite sensitive to this medium. Even if your symptoms do not pass, and the breath is complicated, you should not use this spray longer than seven days. It is best to replace it with another drug. You can do it yourself or by contacting a specialist. He will be able to pick up a high-quality analogue for you, which in his opinion is most suitable for you.
How to replace Ximeline?
It is worth saying that this drug has a fairly large list of drugs that are similar to the testimony and pharmacological action. At the same time, it is very important before using carefully examine the instructions and the composition of the medicine, because it often happens that more expensive drugs contain additives and substances that enhance the effect of the drug. Sometimes this can cause side effects and unpredictable reactions of the body. So, the following nasal can be attributed to the counterparts of Ximelin
The spray of nasal includes basic substances: xylometazoline hydrochloride and monohydrate.
Additional components: Dinatari Edettat Dihydrate, hydrochloric acid, glycerol 85%, sodium hydroxide, purified water.
Form release
Sexeline extra in the form of a nasal spray, packaged in the vials of plastic 10 ml.
pharmachologic effect
Square is characterized by local vasoconducting act.
Pharmacodynamics and pharmacokinetics
In the combined drug, Ximelin Extra includes xylometazoline and bromide Jiprathopia which exhibit anticholinergic activity. Also, the drug has a pronounced effect on the secretory activity of the nasal mucous membranes, compared with non-comberized means.
At the same time, the development of the effect appears after 3-5 minutes from the moment of use, remaining on average 6-10 hours.
As a result of intranasal use, the drug is practically not subjected to absorption and does not have a systematic effect on the body.
The concentrations of active ingredients in the composition are quite negligible and practically not defined even with the help of modern methods and research.
Indications for use
The drug Ximelin Extra is prescribed during treatment:
- acute allergic;
- sharp respiratory diseases accompanied by symptoms of rhinitis or runny nose;
- evstachitis;
- In order to reduce the waste of the nasopharynx mucosa.
As well as during the preparation of patients to various diagnostic procedures in the field of nasal moves.
Contraindications
The use of Ksymelin Extra is contraindicated with:
- sensitivity to its components;
- the presence of diseases of the cardiovascular system, for example, arterial hypertension, and ;
- atrophic;
- childhood up to 2 years;
- , .
Also, the drug is not prescribed to patients who transferred surgical operations on brain shellsEven if they were held for a long time.
Caution is needed in the treatment of patients with , hyperplasia prostatic gland, stress angina, cervical obstruction bladder, fibrosis, violation of intestinal passability, a tendency to various bleeding.
Side effects
The use of this drug is usually not accompanied by the development of side effects. However, one should not exclude the manifestations of local reactions in the form: burning, dryness and irritation of mucous membranes, frequent sneezing. It is also possible to manifest such reactions as a violation of vision, problems with sleep and so on.
Instructions Ximelin Extra (method and dosage)
As indicated by the instruction on the use of spray, it is used intranasally. Before injection drug Nasal moves are carefully cleaned. The duration of treatment and the dosage determines the doctor, taking into account the complexity of the disease and the individual characteristics of each patient.
Usually for adult patients are prescribed 1-2 injection into each nostril 1-3 times a day. On average, the therapeutic course lasts 10 days.
Overdose
Cases of overdose may result in strengthening side effects. At the same time, treatment is carried out taking into account the manifested symptoms.
Interaction
Joint use of Ksymelin Extra and monoaminoxidase inhibitors , as well as tricyclic antidepressants unacceptable.
Simultaneous use with anticholinergic drugs can enhance therapeutic effect Bromide iprathopia.
special instructions
During the period of treatment, it is important to comply with the dosage and duration of use.
The use of drugs based on xylomezoline, especially in high doses, can affect the work nervous system. Therefore, it is recommended to refrain from managing transport and fulfillment of hazardous activities.
Terms of sale
Without recipe.
Storage conditions
For storage, the spray is suitable for the place inaccessible to children, with a temperature of 15-25 ° C.
Shelf life
Ksymelin Extra
Coincidences on the ATX 4 level code:Reviews of Ksymelin Extra
As a rule, treatment of any cold or starts precisely from the use of drops for the nose. Modern pharmacology It offers a large selection of drugs of such action, but funds created on the basis of xylometazoline are particularly popular. Therefore, the reviews about Ksemelin Extra are quite common and the opinion of it is very ambiguous.
Often you can find discussions about the occurrence of drug addiction. Such a state develops quite quickly to a large extent due to frequent use of droplets or spray in elevated dosages. Unfortunately, at the beginning of treatment, many patients try to get rid of the cold as soon as possible, but such carelessness will subsequently require the treatment of drug addiction. According to some users to get rid of her, they needed several years.
As for the treatment of a runny nose with the help of Ksymelin Extra in compliance with the dosage and therapeutic course, the patient reviews are in most positive. The drug helps to quickly and effectively eliminate the manifestations of rhinitis and ease general state Patient man.
A separate topic for active discussion is the use of saline solutions and sea water. It should be noted that it is necessary to use any vasoconstrictors after careful purification of the mucous meters using these solutions. Some patients are used pharmacy, And someone prepares them on their own. By the way, such solutions can be used often and in any dosage. It is recommended to use them in the season of colds as prevention. Often this happens enough to eliminate the symptoms of rhinitis and prevent the development of the disease.
This article allows you to familiarize yourself with the instructions for the use of the drug. Ximeline. Reviews of site visitors - consumers of this medicine are presented, as well as the views of the doctors of specialists in the use of Ksymelin in their practice. A big request to more actively add your reviews about the preparation: helped or did not help the medicine to get rid of the disease, which complications were observed and side effectsmay not be stated by the manufacturer in annotations. Analogs of Ksimlin in the presence of available structural analogs. Use for the treatment of runny nose and half aulinosis in adults, children, as well as during pregnancy and breastfeeding. Composition of the drug.
Ximeline - vasoconstrictor drug For topical use in LOR-Practice. Xylometazoline has an alpha adrenomimetic effect. Causes a narrowing blood vessels The mucous membrane of the nose, eliminating the edema and hyperemia of the nasophack mucosa. Facilitates nasal breathing at rhinitis.
In therapeutic concentrations does not irritate the mucous membrane, does not cause hyperemia.
The action occurs a few minutes after use and continues for 10-12 hours.
Structure
Xylometazoline hydrochloride + excipients (Ximelin and Ximelin Eco with menthol).
Xylometazoline hydrochloride + ipratropy Bromide monohydrate + excipients (Ksemelin Extra).
Pharmacokinetics
For local application Virtually not absorbed. Plasma concentrations are so small that they cannot be determined by modern analytical methods.
Indications
- sharp respiratory diseases with phenomena of rhinitis;
- acute allergic rhinitis;
- pollnosis;
- sinusitis;
- evstachitis;
- medium otitis (to reduce the edema of the nasophack mucosa);
- preparation of a patient for diagnostic manipulations in nasal strokes.
Forms of release
Spray nasal 0.05% and 0.1% (sometimes erroneously called drops in the nose).
Instructions for use and method of use
1 Injecting Ximelin 0.05% contains about 35 μg xylomezoline hydrochloride.
Spray nasal 0.1% prescribe adults and children over 6 years old 1 injection into each nostril (if necessary, you can repeat injection).
1 Injecting Ximeline 0.1% contains about 140 μg xylometazoline hydrochloride.
The drug should be applied not more than 3 times a day and for no more than 7 days. If necessary, more long use Consultation is needed.
Side effect
- irritation and / or dryness mucous membrane sheath;
- burning, paresthesia, chichanye, hypersecretion;
- swelling of the mucous membrane of the nose;
- feeling of heartbeat;
- tachycardia;
- arrhythmias;
- increased blood pressure;
- headache;
- vomiting;
- insomnia;
- vision impairment;
- depression.
Contraindications
- arterial hypertension;
- tachycardia;
- pronounced atherosclerosis;
- glaucoma;
- atrophic rhinitis;
- hyperthyroidism;
- surgical interventions on the brain shells (in history);
- pregnancy;
- children's age up to 2 years (for drug Ximeline 0.05%);
- children's age up to 6 years (for the drug Ximeline 0.1%);
- increased sensitivity to the components of the drug.
Application in pregnancy and breastfeeding
The use of the drug during pregnancy is contraindicated.
During the lactation, Ximelin should be applied only after a thorough assessment of the benefit ratio for mother and risk for babyIt is not allowed to exceed the recommended dose.
Application in children
The drug is contraindicated up to 2 years (for nasal spray).
Drops Nasal 0.05% are prescribed to children aged 2 to 6 years old 1-2 drops in each nostril 1-2 times a day.
Drops Nasal 0.1% are prescribed to children over 6 years old 2-3 drops in each nostril (if necessary, you can repeat the instillation).
Spray nasal 0.05% is prescribed to children aged 2 to 6 years for 1 injection into each nostril 1-2 times a day.
Spray nasal 0.1% prescribe children over 6 years old 1 injection into each nostril (if necessary, you can repeat injection).
special instructions
Caution should be used the drug when sugar diabetes, angina of 3-4 functional class, prostate hyperplasia.
Impact on the ability to driving vehicles and control mechanisms
Medicinal interaction
For sharing With inhibitors of MAO and tricyclic antidepressants, an increase in blood pressure is possible.
Analogs of the Medicinal Czymelin
Structural analogues of PO active substance:
- Brizolin;
- Galazoline;
- Infpostad Reno;
- Manual;
- Dr. Taiss Nazolin;
- Dr. Tasse Rinotaiss;
- Star;
- Influine;
- Xylene;
- Xicle;
- Xilomeazoline;
- Ximeline Eco;
- Ximelin Eco with menthol;
- Ksemelin Extra;
- Nostin;
- Rollyin Balsam;
- Olint;
- Orinary;
- Rinomaris;
- Rinonorm;
- Rinorus;
- Rosotop;
- Sanarin xylo;
- Salor;
- Snup;
- Super;
- Tizin Ksilo;
- Tizin xylo bio;
- Pharmazoline;
- Eucazolin Aqua;
- Espazolin.
In the absence of analogues of drugs on the active substance, you can follow the links below on the disease, which helps the appropriate drug, and see the analogues on therapeutic effects.
Ximelin Extra: Instructions for use and reviews
Latin name: Xymelin Extra
ATX code: r01ab06
Active substance: Bromide Ipratropia (Ipratropium Bromide) + Xylometazoline (xylometazoline)
Manufacturer: Takeda GmbH (Germany), Nycomed Pharma (Norway)
Actualization of the description and photo: 21.11.2018
Ximeline Extra is a local combined drug with a vasoconductive effect used in LOR-Practice.
Release form and composition
Dosage form of release of Ksimelin Extra - Spray Nasal: Transparent, colorless or somewhat painted (in a cardboard pack - 1 plastic bottle with a pump dosing device of 10 ml).
Active substances consisting of 1 dose of spray:
- xylometazoline hydrochloride - 0.07 mg;
- monohydrate Bromide IPratropy - 0.084 mg.
Auxiliary components: Dinatari Edetate Dihydrate - 0.07 mg; 85% glycerol - 3.91 mg; Concentrated chloride hydrochloric acid - to pH 4.5; sodium hydroxide - to pH; Purified water - up to 0.14 ml.
Pharmacological properties
Pharmacodynamics
Ksemelin Extra refers to the number of local combined drugsused in LOR-Practice.
The main properties of components:
- xylometazoline: is an alpha adrenomimetic. It leads to a narrowing of blood vessels of the nasal mucosa, which helps to eliminate edema and hyperemia of the nasopharmaceous mucosa. At rhinitis facilitates nasal breathing;
- bromide Ipratopia: has an anticholinergic property. In case of intranasal use, it helps to reduce the secretion of the glance of the nasal mucosa.
With the use of the drug in therapeutic doses, the mucous membrane does not irritate and hyperemia does not occur.
The EXTRA EXTRA is evaluated after 5-10 minutes, its duration is 6-8 hours.
Pharmacokinetics
In case of intranasal application active components Ksimelina Extra is absorbed little, their plasma concentration is insignificant.
Indications for use
- swelling and hyperemia of the nasal cavity (symptomatic therapy);
- acute respiratory diseases with rhinitis phenomena;
- sinusitis;
- pollnosis;
- acute allergic rhinitis.
Contraindications
Absolute:
- atrophic rhinitis;
- arterial hypertension;
- burdened anamnesis on surgical interventions on brain shears;
- thyrotoxicosis;
- tachycardia;
- glaucoma;
- pronounced atherosclerosis;
- age up to 18 years;
- I trimester of pregnancy;
- individual intolerance to the components of the drug.
Relative (Ksymelin Extra is appointed under medical control):
- fibergation;
- prostate hyperplasia;
- diabetes;
- obstruction of the bladder neck;
- angina of the III-IV functional class;
- the presence of predisposition to the development of the following diseases / states: nasal bleeding, paralytic intestinal obstruction, dizziness, tremor of skeletal muscles, sleep disorders, arrhythmia, increase blood pressure;
- II-III trimesters of pregnancy and lactation period.
Instructions for use of Ksymelin Extra: method and dosage
Ksymelin Extra applies intranasal.
Side effects
Possible adverse reactions with frequent / long-term use: dryness / irritation of the nasophack mucosa, nasal bleeding, sneezing, burning and tingling in the throat and nose, headache, swelling of the nasal mucosa, hypersecretion of the nasal cavity mucosa.
In rare cases, the development of the following violations is noted: insomnia, headache, systemic allergic reactions, dizziness, violation, tachycardia, heartbeat, arrhythmia, an increase in blood pressure.
Overdose
The appearance of acute overdose after intranasal use of Ksimelin Extra is unlikely, since the absorption of its actors is extremely slightly.
The main symptoms are manifested in the form of xerostomy, disorders of accommodation, tachycardia, headaches, arterial hypertension.
Therapy: symptomatic. The abolition of the drug is shown.
special instructions
Before applying Ksimelin Extra nasal moves must be cleaned.
Long therapy, for example, chronic rheint, not recommended.
Spray can not be sprayed or around them. In the case of sending Ksimlin, Extra in their eyes should be rinsed with cold water.
If after three days of therapy therapy the condition did not improve or worsened, you need to consult with your doctor.
Impact on the ability to control vehicles and complex mechanisms
According to the instructions, Ksemelin Extra can influence the ability to manage motor vehicles In case of an overdose or spray in the eye.
Application during pregnancy and lactation
- I trimester of pregnancy: therapy is contraindicated;
- II-III Trimetras of pregnancy and lactation period: Ksemelin Extra can be applied after the doctor will estimate the ratio of expected benefit from possible risk. Excess therapeutic doses should not be.
Childcare
Ximeline Extra patients under 18 are not appointed.
Medicinal interaction
Possible interactions:
- monoaminoxidase inhibitors: arterial pressure rises;
- three and tetracyclic antidepressants: the sympathomimic effect of xylometazoline is enhanced;
- other anticholinergic preparations: Anticholinergic effect of bromide, ipratopia can be intensified.
Analogs
Analogue of Ksimelina Extra is the deryvin complex.
Terms and conditions of storage
Store at temperatures up to 25 ° C. Take care of children.
Shelf life - 3 years.
Topic Decongestant Ksimelin Extra - Combined drug Treatment, widely used in LOR-Practice.
As you know, the nose performs an olfactory, respiratory and protective function. With the help of a nasal cavity, some centers in the CNS receive environmental information.
Rinith is considered one of frequent diseases Upper respiratory tract, As a result of which the patient loses a complete sense of smell and is in a state of permanent hypoxia.
Ximelin Extra Spray: The composition of the drug and the release form
The medicine in its composition has two active components:Xylometazoline is a substance from the group of alpha adrenomimetics. Impact on special receptors, it causes a narrowing (content) of small blood vessels of the nasal mucosa by type of arteriole.
Ksemelin Extra photo Thus, it is reduced by the anti-acudative effect and eliminate local hyperemia, which allows the patient to breathe freely.
When used in therapeutic dosages, xylometazoline is practically not absorbed into the system channel and does not cause common reactions.
Bromide Jiprathopia - The second active ingredient of the drug with a cholinolitical effect. An application point is blocking M-cholinergic receptors, which are located in smooth muscle cells of tracheobronchial wood and nasopharynx.
The substance expands large and medium bronchi, prevents their spontaneous content. In addition, the bromide and bromide suppresses the secretion of mucus with iron epithelial nasal shell, which reduces the local edema.
Zimeline nose spray also has auxiliary substances: sodium hydroxide, water, 85% glycerol, concentrated hydrochloric acid, Dinatari Edetat.
IN dosage form The drug presented the following description: Nasal spray, which has a colorless transparent solution and is enclosed in plastic bottle with a dispenser.
The tool is also available in the form of droplets intended only for intranasal use. 
Contraindications
Annotation of the drug contains detailed information regarding contraindications in which the destination of the spray is inappropriate and even dangerous.
These include:
- Decompensated and poorly controlled heart disease and vascular system - atherosclerosis, arrhythmias, paroxysmal tachycardia, hypertonic disease, heart failure.
- - That is, the spray is not appointed to persons under 18.
- Hyperthyroidism - Pathology thyroid glandaccompanied by its hyperfunction; diabetes.
- - When the nasal mucosa is found.
- Glaucoma - eye disease, in which intraocular pressure is significantly increased.
- Hypersensitivity to drug components - the development of both local and systemic allergic reactions.
Side effect
In Ksymelin Extra, the instruction on application is mandatory invested in cardboard packaging with a bottle, so its reading is very important. With incorrectly or unreasonably long use of the decongestant possible
As a rule, it is irritation, frequent chisanier, a sense of tingling or intensive burning. 
Much less often treatment with the drug is exacerbated by the edema of the mucous and increasing the amount of discharge from the nose.
It is worth noting
Among the total adverse reactions, an increase in systemic pressure, the occurrence of arrhythmia or tachycardia, headaches, deterioration of visual acuity, sleep inversion and depressive states are noted.
Dyspeptic side effects include nausea and much less often - one-time vomiting.
Ximelin Extra: Indications for use
First of all, the drug is used from a runny nose, which can be like an independent disease and a symptom of infectious pathology.
What are Ksymelin appointed from:
- Respiratory viral infections
- Inflammation of the hearing pipe.
- Sinusits.
- Acute form of allergic rhinitis.
- The average catarrhal otitis (in order to reduce the edema of the mucous membrane).
Ximelin Extra: dosage and use method
Spray is intended only for intranasal administration. Before use of the drug, it is recommended to clean the nasal moves from the mucus and crusts accumulated in them.
This can be done with the help of moistened in the cooled boiled water, or using the physiological solution (the nose is washed with a syringe without a needle).
Next, the protective cap is removed from the bottle, and the tip is neatly introduced into the nose. The mucosa is irrigated after the compression of the bottle. 
The same manipulation should be repeated with a second nose. At the end, the tip of the sprayer is cleaned and closed with a cap.
Instructions for use for children
As mentioned above, in childhood it is forbidden to use extras spray. At the same time, children are prescribed or ordinary spray.
0.05% Spray is allowed to use from two years: on the 1st dose one or twice a day. It is not recommended to squander the child more than three times. 0.1% spray applied in children who have reached the age of 6 are already three injunctions. The duration of such treatment is not more than 7 days.
Zimelin's nasal drops are prescribed to children in 0.05% concentration. Entered 1st or 2 drops in each nasal stroke to three times a day. At the same time, it should be pre-cleaned the nasal cavity.
Is it possible during pregnancy and breastfeeding?
The first trimester of pregnancy is an extremely undesirable period for the use of similar drugs. For pregnant women at a later date, as well as lactating women, it is permissible to use spray only after evaluating the expected positive effects and possible harm on the body of the fetus. It is important not to exceed the dose and duration of therapy specified in the instructions.
How much is Ksemelin Extra: Price
Spray Ximelin Extra: Analogs Cheaper
Similar analogues in composition, but with a lower cost:
- which is also produced in the form of droplets and spray.
- Xylometazoline or xylene.
- Oxymetazoline.
- Vibrocil.
- Nazivin
- Otrivin.
- Noksprey.
These drugs also have a vasoconstrictor effect and have similar indications. Due to the presence of two forms (droplets and spray) are permissible to use in childhood.
Terms and Storage Terms
The manufacturer indicates that the drug should be stored at an ambient temperature of no more than 30 and in the place protected from children.
Questions
Does allergies help?
One of the testimony to the medium is but it is worth noting that the drug is not specific therapy, but is used only for symptomatic treatment.
Reducing the swelling and products of mucus, Ximelin will help to eliminate the first symptoms in allergies, but the main treatment should include antihistamines, and with more severe course - Topic steroids.
Ximeline vasoconishing or not?
The medication includes xylometazoline, which has a vasoconstrictor effect on the epithelial shell of the nose. Due to this, the main effects of the drug are achieved.
At the same time, it is not recommended for a long time (more than 10 days) to use it, since in most cases develops 
What is the difference between Ksimlin Eco from Ximelin Eco?
The Ksimeline Eco does not include bromide, and xylometazoline is contained in a significantly lower concentration (140 μg against 500). Also, the medication is characterized by the fact that it is allowed to children from 10 years.
So, Ximelin is a highly efficient topical decongestant, which is actively used in the treatment of a cold in adults and children.
