"Alloquin-Alpha": Analogues of Russian, instructions for use, side effects, contraindications. Alloin Alpha - instructions for use, indications, release form, side effects, analogues and price instructions for use. Contraindications and form
Antiviral agent - Oligopeptide (Gistidin - Glycine - Valin - Serin - Glycine - Gistidin - Glycine - Glutamin - Gistidin - Glycine - Valin - Gistidin - Glycine), according to the pharmacological action is close to Interferon Alpha.
Inductor synthesis of endogenous interferonov and an activator of the NK killer system. Stimulates recognition and lysis of defective cells cytotoxic lymphocytes. Effective in infections caused by influenza viruses A and B, hepatitis C, herpes.
Does not have overall toxicity, allergenic, mutagenic, carcinogenic, embryotoxic effect and does not affect the reproductive function.
An increase in interferon concentration is observed 2 hours after the administration of the drug; high concentration persists (2-2.5 times higher than the usual background) for 6-8 hours with a decrease to the initial values \u200b\u200bby the end of the day. Increased functional activity of NK killers is observed within 7 days after the administration of the drug.
Pharmacokinetics
Quickly penetrates the plasma of blood, where interacts with immunocompetent cells. The definition of the concentration is difficult to close structural similarity of its metabolites with serum proteins.Form release
Lyophilisate for the preparation of a solution for p / k administration in the form of a powder or porous mass, white, odorless; Gigroscopic.
1 mg - ampoules (1) - Packaging Corner contour (1) - packs cardboard.
1 mg - ampoules (2) - Packaging Cell Contour (1) - Cardboard packs.
1 mg - ampoules (3) - Packaging Cell Contour (1) - Cardboard packs.
1 mg - ampoules (5) - Packaging Corner contour (1) - packs cardboard.
1 mg - ampoules (10) - Packaging cell contour (1) - packs cardboard.
Dosage
Prescribe p / k.
At a relapse frequency of more than 6 per year and duration of more than 5 days in the first relapse, 3 administration at a dose of 10 mg was recommended with an interval of 1 day, in the following relapse - 1-3 injections of 1 mg, in the subsequent relapse - 1-3 administration of 0.1 mg.
At a relapse frequency frequency, less than 6 per year and the duration of less than 5 days is recommended 3 administration at intervals in 1 day 1 mg, to the following relapse - 1-3 injections of 0.1 mg.
Before administration, the preparation is dissolved in 1 ml of 0.9% sodium chloride solution.
Side effects
It is possible: weakness, dizziness, the formation of new elements of herpetic rash.
Lyophilisate for the preparation of a solution for p / k administration in the form of a powder or porous mass, white, odorless; Gigroscopic.
1 AMP. Contains: histidyl-glycyl-valve-serinal glycil-histidyl-glycil-glutaminyl-histidyl-glycil-valle-gistidyl-glycine - 1 mg
Release form:
- 1 mg - ampoules (1) - Packaging Corner contour (1) - packs cardboard.
- 1 mg - ampoules (1) - Packaging cell contour (2) - packs cardboard.
- 1 mg - ampoules (2) - Packaging Cell Contour (1) - Cardboard packs.
- 1 mg - ampoules (2) - Packaging cell contour (2) - packs cardboard.
- 1 mg - ampoules (3) - Packaging Cell Contour (1) - Cardboard packs.
- 1 mg - ampoules (3) - Packaging Cell Contour (2) - Cardboard packs.
- 1 mg - ampoules (5) - Packaging Corner contour (1) - packs cardboard.
- 1 mg - ampoules (5) - Packaging cell contour (2) - packs cardboard.
- 1 mg - ampoules (10) - Packaging cell contour (1) - packs cardboard.
- 1 mg - ampoules (10) - Packaging cell contour (2) - packs cardboard.
pharmachologic effect
Alloferon is an oligopeptide. The nature pharmacological action The most similar to Interferon Alpha. Alloferon is an effective inducer of the synthesis of endogenous interferon and the activator of a natural killer system, is able to stimulate the disintegration and lysis of defective cells by cytotoxic lymphocytes. Experiments are demonstrated high efficiency With regard to infections caused by influenza viruses A and B, hepatitis B and C, herpes 1 and 2 types and human papillomas. Alloferon does not have overall toxicity, allergenic properties, mutagenic and carcinogenic effect, does not have embryotoxic effect and does not affect the reproductive function.
Pharmacokinetics
Quickly penetrates the blood, where interacts with immunocompetent cells, after which the determination of the concentration of the alloofon is difficult due to the close structural similarity of its metabolites with serum proteins. Increased interferon concentration was noted 2 hours after the administration of the drug and was maintained on high level (2-2.5 times higher than the usual background) for 6-8 hours with the achievement of initial values \u200b\u200bby the end of the day. Increased functional activity of natural killers was observed within 7 days after the administration of the drug.
Indications for the use of Alloin Alpha
- chronic recurrent herpes 1 and 2 types;
- as part complex therapy Medium (jaundice) form of acute hepatitis V.
Contraindications for the use of alloin-alpha
- pronounced autoimmune diseases;
- pregnancy;
- lactation period;
- childhood;
- increased sensitivity to the components of the drug.
Alloin-Alpha Application during pregnancy and children
Preparation of probe and lactation during pregnancy
Contraindicated in childhood.
Alloin-Alpha Side effects
In some cases, weakness, dizziness, the formation of new elements of the rash (with a herpes infection) is possible.
Medicinal interaction
In the treatment of chronic recurrent genital herpes, it may be prescribed in combination with acyclovir and its derivatives (drugs have a different mechanism of action and complement each other in the treatment of viral infection).
In acute hepatitis, the drug is appointed against the background of generally accepted basic therapy.
Interaction with others drugs not found.
Alloquin Alpha Dosage
The drug is administered in / k.
The standard course of treatment of Herpes relapse includes the injection of the drug at a dose of 1 mg every other day, throughout the course - 3 injections.
With moderate forms of acute hepatitis, the drug is administered after verification of the diagnosis at a dose of 1 mg 3 times a week for 3 weeks (total 9 injections).
To prepare a solution for injections as a solvent, use 1 ml of 0.9% sodium chloride solution.
Overdose
Until now, there was no overdose of the drug.
Instructions for use. Contraindications and form of release.
Instruction
by medical application drug
Alloin Alpha
Allokin-Alfa)
pharmachologic effect
Alloin Alpha - antiviral drug, active in relation to influenza viruses, hepatitis C and B, first and second type of herpes virus, as well as a human papilloma virus (in particular with respect to oncogenic strains of human papillomavirus). Alloin-alpha contains alloferon - oligopeptide, induced synthesis of endogenous interferon and activating system of natural killers. Alloferon contributes to recognition and lysis cytotoxic lymphocytes of defective cells.
The effectiveness of the drug of Alloin-Alpha in the treatment of diseases caused by the human papillomavirus, the flu virus (including type B and type A), the hepatitis C virus and B, as well as the virus of a simple herpes of the second and first type.
Alloferon is small, does not cause development allergic reactionsand also does not have teratogenic, mutagenic and embryotoxic effect and carcinogenic effect. In the course of research, Alloin-Alpha did not reveal a negative effect on the reproductive system of animals and humans.
With subcutaneous administration, the alloferon quickly penetrates into systemic bloodstream and interacts with cells. Alloferon metabolites have a structure similar to plasma proteins, so they are difficult to identify blood plasma.
Within 2 hours after the administration of Alloin-Alpha drug, the patients have an increase in interferon concentrations, which remained for 6-8 hours (at the same time the level of interferon exceeded the usual background 2-2.5 times).
Increased activity of natural killers persisted within 7 days after one-time administration of alloferon.
Indications for use
Alokine-Alpha is used for the treatment of patients suffering from chronic papillomavirus infection, which is associated with oncogenic types of human papilloma virus. Alloferon can be used as a monotherapy of papillomavirus infection in the absence of clinical and subclinical lesions of the cervix and anogenital region, if similar lesions are present, the Alloferon is recommended to be used in a complex with other drugs.
Alloin-alpha is prescribed in the complex therapy of chronic recurrent herpes of the second and first type (in this case, start the therapy should be as early as possible after the first symptoms appear).
Alloferon in a complex with other drugs is used in patient therapy with acute hepatitis IN middle degree Severity (therapy by the drug Alloin-Alpha should be started no later than the seventh day after the appearance of jaundice).
Mode of application
Alloin-alpha preparation is designed for making a solution for subcutaneous administration. To prepare a solution, the contents of the ampoule should be dissolved in 1 ml of isotonic sodium chloride solution. It is not recommended to use other drugs as a solvent. Alloin Alpha is prohibited to mix with one syringe with others parenteral drugs. Use alloin-alpha solution immediately after cooking. The duration of therapy and the application of the use of alloferone determines the doctor.
In case of infections caused by oncogenic species of human papillomavirus, as a rule, administration of 1 mg of alloferon is prescribed every 48 hours.
The total recommended coupling dose of Alloin-Alpha preparation is 6 injections.
With a recurrent herpetic infection, as a rule, administration of 1 mg of alloferon is prescribed during the exacerbation every 48 hours.
The total recommended course dose of Alloin-Alpha preparation is 3 injections.
Patients with acute hepatitis in the average severity, as a rule, after verification of the diagnosis, administration of 1 mg of alloferon is prescribed three times a week.
The overall recommended course dose of Alloin-Alpha preparation is 9 injections.
Depending on the state of the patient and the effectiveness of the treatment, a doctor may prescribe a repeated course of the use of Alloin-Alpha preparation.
Side effects
Alloin-Alpha, as a rule, is well tolerated by patients. During the test, the drug has been reported on isolated cases of development of weakness and dizziness.
In addition, patients with herpetic infection may have the appearance of new rash elements.
Contraindications
Alokine-alpha is not prescribed to patients with individual intolerance of alloferon.
Alloin-Alpha does not apply for patient therapy suffering from expressed autoimmune diseases.
IN pediatric practice The use of alloferon is not recommended.
If patients have dizziness development during the period of therapy by Alloferon, activities that require increased concentration of attention should be excluded.
Pregnancy
It is forbidden to use the drug Alloin-Alpha during pregnancy.
During breastfeeding It is not desirable to use alloferon. If you avoid the prescription of the drug Alloin-Alpha during the lactation period, it is impossible to be resolved the question of interrupting breastfeeding.
Medicinal interaction
The combined use of the drug of alloin-alpha with acyclovir in the treatment of patients suffering from a chronic recurrent form of genital herpes (due to the different mechanisms of action of alloferon and acyclovir mutually potentiate antiviral action of each other).
The simultaneous use of alloferon with the means of basic therapy of hepatitis V.
Overdose
There is no data on the overdose of Alloin-Alpha.
Form release
Powder lyophilized for the preparation of a solution for subcutaneous use of alloin-alpha 1 mg in ampoules, in a cardboard pack 1, 2, 3, 5, or 10 ampoules placed in cellular packaging from polymeric materials.
Storage conditions
Alloin-Alpha should be stored no more than 2 years after the release in rooms with a temperature regime from 2 to 8 degrees Celsius.
Ready solution to store is prohibited.
Structure
1 ampoule Alloin Alpha preparation contains:
Alloferon - 1 mg.
This page provides a list. analogs of Alloin Alpha - these are interchangeable drugs that have similar indications for use and belong to one pharmacological group. Before buying analog Alloin AlphaIt is necessary to consult with a specialist regarding the replacement of the drug, to study in detail, read and similar to it.
Valtrex.
A drug Valtrex. Designed as the treatment of herpes skewers;
Treatment of diseases of the skin and mucous membranes caused by the Herpes Simplex virus of types 1 and 2 (including the firstly identified and recurrent genital herpes);
Prevention of recurrence of skin diseases and mucous membranes caused by the Herpes Simplex virus types 1 and 2 (including genital herpes);
Prevention of cytomegalovirus infection and diseases developing after organ transplantation. Prevention with help Valtrel Reduces the reaction of the rejection of the transplantation, the development of infections caused by convention and pathogenic microorganisms, and other viral infections (including a herpes sling).Famciclovir
Famciclovir prescribed for the treatment of sliding linging, postherpetic neuralgia, recurrent genital herpes.
Zovirax.
Zovirax. prescribed for the following diseases:
- treatment of infections caused by the Herpes Simplex type 1 and 2 virus;
- Prevention of infections caused by the Herpes Simplex type 1 and 2 virus in patients with immunodeficiency;
- Treatment of infections caused by the VARICELLA ZOSTER virus (chickenpox and herpes hawker);
- treatment of infections caused by the Herpes Simplex type 1 and 2 virus in newborns;
- Prevention of cytomegalovirus infection in the recipients of bone marrow transplants.
Eye ointment:
- Treatment of keratitis caused by the Herpes Simplex type 1 and 2 virus.Tamiflu
Tamifluit is used to treat influenza caused by viruses of types A and B, in adults and children over the age of 1 year.
Typical influenza symptoms arise suddenly and include fever, cough, headache, severe weakness, pain in muscles and throat pain.
Flu prophylaxis in adults and adolescents over 12 years old, which are in groups of increased risk of infection with the virus (in military units and large production teams, in weakened patients).
Novirin
Novirinare:
- Infectious diseases viral etiology in patients with normal and reduced immune status: flu, paragripp, sharp respiratory viral infections, bronchitis of viral etiology, rinoviral and adenovirus infections; Epidemic parotitis, korch;
- diseases caused by the viruses of simple herpes Herpes Simplex I or II type (herpes of lips, face skin, oral mucosa, hands, ophthalmoherpes), subacute sclerosing pankenefalitis, genital herpes VARICELLA ZOSTER virus ( chickenpox and listened, including recurrent in patients with immunodeficiency); Epstein-Barra virus ( infectious mononucleosis) cytomegalovirus; Papillomavirus man; Acute and chronic viral hepatitis IN;
- Chronic recurrent infections respiratory tract and the urogenital system in patients with weakened immunity (chlamydia and other diseases caused by intracellular causative agents).
Gancyclovir
A drug Gancyclovirused:
- For the treatment of threatening life or the vision of the manifest CMV infection in individuals with immunodeficiency, including AIDS, yathedral immunodeficiency associated with the transplantation of organs or chemotherapy of neoplasms.
- In order to prevent the manifest CMV infection in patients receiving immunosuppressive therapy after organ transplantation.
Normomed
Lamivudine
Miomin
Gepsera
Daklyza
Soledi
Sofosbuvir
AtriPla
Combivir
Stockinian
Tenvir EM
Eduista
Mavirth
Jewel
A drug Jewelit is applied for:
- treating herpes skewers;
- the treatment and prevention of relapses of skin infections and mucous membranes caused by a variece virus (including the first time identified and recurrent genital herpes);
- treatment of labial herpes;
- reducing the risk of infection with genital herpes of a healthy partner if it is taken as supgrass therapy in combination with safe sex;
- Prevention of cytomegaloviral infection arising from organ transplantation (reduces the severity of the reaction of acute transplant rejection in patients with kidney transplants, the development of opportunistic infections and other viral infections caused by Herpes Simplex and Varicella Zoster viruses) in adults and children over 12 years old.
Sophoswell
A drug Sophoswell shown for the treatment of adults suffering from hepatitis C in chronic form Gotypes 1, 2, 3, 4, and 6, as well as patients suffering from compensated or decompensated cirrhosis of the liver.Valmaks.
Indications for the use of the drug Valmaks.are:
- Treatment of herpes haying (Herpes Zoster).
- Treatment of skin infections and mucous membranes caused by a variety of herpes virus, including primary and recurrent genital herpes.
- Treatment of labial herpes (lifting fever).
- Preventive treatment (suppression) of the recurrence of skin infections and mucous membranes caused by a variety of herpes simplex, including genital herpes.
- Reducing the transfer of genital herpes virus to a healthy partner when using Valmax as suppressive therapy in combination with safe sex.
- Prevention of cytomegalovirus infection and disease after organ transplantation.
Viread.
Vireadit is applied for:
- Treatment of HIV-1 infection in adults in combination with other antiretroviral and drugs.
- Treatment of HIV-1 infection in children aged 12 to 18 years old with the presence of resistance to non-reverse transcriptase inhibitors, or toxicity excluding the possibility of using antiretroviral preparations of the first line.
A drug Vireadused in the treatment of hepatitis in:
Treatment of chronic hepatitis in adults with:
- compensated liver disease, signs of active replication of the virus, permanent increased activity in the blood serum Alaninotransferase (ALT) and histologically confirmed active inflammatory process and / or fibrosis;
- proven by the presence of resistance of VGV clamavudine;
- decompiled liver disease.
Treatment of chronic hepatitis B in children aged 12 to 18 years old
- compensated liver disease with signs of an active inflammatory process and active replication of the virus, which is confirmed by the constant increased activity of Alt in blood serum and histologically confirmed active inflammatory process and / or fibrosis.
Sebivo
A drug Sebivoit is used to treat chronic hepatitis B in adult patients with confirmed virus replication and an active inflammatory process in the liver.
Vacyrex
A drug Vacyrexit is used to treat adults: lispy; diseases of the skin and mucous membranes caused by the Herpes Simplex virus (incl. genital herpes); Prevention of recurrence diseases caused by the Herpes Simplex virus.
In adults and children from 12 years: prevention of cytomegalovirus infection during organ transplantation.
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Alloin-Alpha was prescribed from HPV. I heard about the effectiveness of Alloin, but when the doctor prescribed it to me and assured that the drug is qualitative and tested by time, there was no doubt. In the end, 6 injections were enough to get rid of HPV. The results of PCR control after 3 months-negative. I sincerely recommend!
Eugene.
The preparation is worth. I helped me. When HPV found, the doctor advised these injections to pierce these injections. Six months later, I went to take the analysis again on HPV. The result is missing. I hope the effect of it will be long. If it is revealed again, I will prick again. I helped :)
The first alokine punctured Russian when there was access to drugs in general. Then our White Church. The difference is significant, even then, as a drug was found, there was pain from Russian. Our drug is vyolol, it is not clear what kind of sterile water is somehow without any feeling. In Egypt, for fake preparations, the death penalty is creative ... The first alokine punctured Russian when there was access to drugs in general. Then our White Church. The difference is significant, even then, as a drug was found, there was pain from Russian. Our drug is vyolol, it is not clear what kind of sterile water is somehow without any feeling. In Egypt, for fake preparations the death penalty, we do what they want.
I tried a lot of money from HPV. I found 16/18 types. Everything is praised, and the result is in fact zero. Only money translated into drugs. Alokine recommended, said 6 injections, but warned that a repeated course of treatment is possible. After 6 injections, I did not even go to PCR control. Immediately punctured 6 injections ... I tried a lot of money from HPV. I found 16/18 types. Everything is praised, and the result is in fact zero. Only money translated into drugs. Alokine recommended, said 6 injections, but warned that a repeated course of treatment is possible. After 6 injections, I did not even go to PCR control. Immediately punctured 6 injections every other day, and then over and a month later, 3 more injections. After another 4 months passed on PCR. I don't have more HPV! Very pleased with Allokin !!!
I bought 6 injelers to the treatment of pointed dondlomil, I was very much hoping for this expensive preparation made 1 point to the operation to remove Condyl and the rest after, I thought would help but did not help, the Condylomes climbed, until it began to be treated with other drugs and 2 more removal operations I bought 6 injections to the treatment of pointed Kondille 6, I was very hoping for this expensive vacuum made 1 injection before the operation to remove the royal and the rest after, thought would help but did not help,
Condylomes further closed until he began to be treated with other drugs and 2 more removal operations did
Treated many times from genital herpes, tried everything possible drugs Ointment and tablets. Tired of frequent and exhaustive recurrences, at least once every two months !!! I understand that there will be no complete getting rid of herpes, but at least to achieve remission long. I came across the info about Alloin and decided to try. Asked in ... He was treated many times from genital herpes, tried all possible ointments and tablets. Tired of frequent and exhaustive recurrences, at least once every two months !!! I understand that there will be no complete getting rid of herpes, but at least to achieve remission long. I came across the info about Alloin and decided to try. He asked in pharmacies, but we have no alloin in Baku. I ordered two packs from Moscow at once. Plugged 3 injections, 6 months I do not remember herpes! I think for the prevention to pierce again.
Perfectly helped me with HPV16. Poted the diagnosis, frightened. The doctor said that no need to be nervous, but it was necessary to be treated. Assigned Alloin. Pricks to do easy, just 6 pcs. Analyzes passed after 3 months and really helped!
Alloin helped, did not even have to remove papillomas. Signed for removal, and they themselves began to fall off.
The preparation is beautiful. There were several types of treatment, high viral load. After 4 months he checked - nothing was found. Satisfied.
Alloin-alpha is an excellent drug. I had to order it from Russia, since it is not yet in Baku!. Course has passed along with her husband, after 4 months, the types of HPV 16 and 18 were not detected. The treatment did not happen, but the result is worth the money spent. Recomend for everybody! Alloin-alpha is an excellent drug. I had to order it from Russia, since it is not yet in Baku!. Course has passed along with her husband, after 4 months, the types of HPV 16 and 18 were not detected. The treatment did not happen, but the result is worth the money spent. Recomend for everybody!
The drug is excellent. Helped. But about HPV can only say one thing: it is better not to infect and then do not run in a panic in the doctors and not know what to do. If already infected, Alloin will help.
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