This material is subjective, not advertising and does not serve as a guide to purchase. Before buying, you need consultation with a specialist.
Hypertension is so common among middle and elderly among people, which many people perceive it as commonplace and norm. But it is the increased blood pressure that most often leads to vascular catastrophes, the mortality of which is in the first place in the world population. Arterial hypertension and atherosclerosis causes heart attacks and strokes, death and disability.
In the ranking medicinal preparations There are means of various pharmacological groups, but they are all united by the ability to fight increased arterial pressure. You should warn readers from self-medication and attempts to acquire these medicines without appointing a doctor. The popularity of drugs does not mean their safety and the possibility of uncontrolled application. These are serious preparations that can interact with other drugs, have different side effects, while overdosing dramatically lower blood pressure, and for their purpose, it is sometimes necessary to carefully examine the cardiologist.
Preparations from the Sartan group occupy a leading place in the drug market that protect against arterial hypertension. This medicine does not affect the heart and on the vessels. The effect of all Sartan is that they make insensitive vessel receptors to angiotensule, which is the final link of the conversion cascade, causing the narrowing of the vessels. When receiving losartan, blood pressure decreases immediately, already in the first hours.
Available in three dosages, 12.5 mg, 50 and 100. Indications for receiving is hypertensive disease, chronic heart failure with edema and shortness of breath, as well as prevention of the development of heart attack and hypertension. Apply Lozell regardless of food intake, one-time. At the beginning of therapy, the dosage is 50 mg per day. The most pronounced action is developing a month after the start of receiving the drug. Also, this drug can be used in patients with diabetic kidney damage. It produces Lozec Czech company Zentiv, and packaging for a month, consisting of 30 tablets of a standard dosage of 50 mg, can be purchased for 235 rubles.
Positive properties of this medicine include good tolerability and rare development. side phenomena, of which it is more common headache, dryness of the nose or the development of weakness. In the event that patients have a violation of the liver and kidney function, the specialist consultation is needed, for the dose correction. Also, the advantage is the opportunity to prescribe a lot with other drugs to reduce pressure, but each case should be appointed by the attending physician.
Perhaps, the captopril is the most common drug, and it belongs to the blockers of enzymes catalyzing the conversion of angiotensin, as a result of a suspension vessel and an increase in blood pressure. Captopril is able to fight heart failure, with a kidney damage during diabetes, and prevent repeated episodes of myocardial infarction. The drug is prescribed in dosages 25 and 50 mg according to the scheme given by the doctor. Captopril is extremely popular, he has dozens of various form of release, of which the most accessible are extremely low price. So, the domestic drug production of OOO Ozone has the cost of 10 rubles. For packing of 40 tablets of 25 mg.
Captopril is good because it is able to quickly reduce blood pressure in a hypertension, and to prevent themselves from a heart attack and stroke than he deserved a place in this ranking. When taking the subsybook of one tablet, pressure decreases literally in minutes. Positive qualities include the cheapness of the drug. Captive can also have various contraindications and restrictions on use, to evaluate which only a doctor, for example, bilateral narrowing of renal arteries. It is undesirable to use it for long-term therapy, since it can dramatically reduce blood pressure, which can provoke a violation of cerebral circulation in the elderly.
This drug refers to diuretic means, which remove excess fluid from the body, while the drug reduces blood pressure. In addition, Indapamide improves the tone of arterial walls, and reduces the excessive development of the heart muscle (myocardial hypertrophy). The drug is usually taken on one tablet (1.5 mg) per day, in the morning. The most popular commercial name of the original Indapamide, which first appeared on the market - Arifon Retard (slow release of the drug). The drug is produced by the French company SERVE, the tablets of oval form provide a slow release of the substance, which makes it possible to apply it in contrast to the usual Indapamide once a day. The packaging of the drug, calculated for the month, will cost 300 rubles.
The advantages of the drug include an impact on urine formation in minor doses - it is not a diuretic in fact, only on belonging to the group, one-time application, a good stabilization effect arterial pressure. That is why it is not necessary to take the arithon retard to reduce the swelling, and it should be taken only to reduce blood pressure. This drug also got into a rating as a result of its good tolerability in various groups of patients, and in connection with the ability to take it in old age in patients with diabetes and elevated body weight. Also should not be discounted and an affordable cost of about 10 rubles. for day reception. The disadvantages of the drug refers to its ban on the reception in patients with severe renal and liver failure, as well as with lactose intolerance.
Amlodipine is a blocker of slow calcium channels, and an extremely popular preparation for treatment hypertensive disease. It is worth noting that, in addition to the first and original producer of Amlodipine, Pfizer, there are more than 3 dozen different copies of "other amlodipins" in different dosages. A standard Norvask is produced in tablets of 5 and 10 mg.
In addition to lowering blood pressure, amlodipine has an anti-infanal effect, that is, prevents the occurrence of the attack of angina. Amlodipine is able to lower the pressure for a long time, expanding the vessels. When receiving one tablet Norvska, blood pressure decreases for the whole day. Take amlodipine is necessary due to such a steady effect once a day, drink a small amount of water.
The initial dose is usually 5 mg, but, by decision of the attending physician, it can be enlarged twice. Original amlodipine, or Norvask, can be purchased in a minimum dosage of 5 mg calculated for a month of reception, at a price of 460 rubles. The most accessible analogue of domestic amlodipine can be purchased in the same dosage and in the same quantity from the company Ozone just at a price of 10 rubles. for packaging. But it remains an open question about the quality of the initial substance, which is used by the original Pfizer company and the quality of the domestic drug. The choice makes the patient.
The advantages of amlodipine include a persistent and long-term hypotensive effect, as well as the ability to treat immediately and hypertension, and angina. For this universal action, he earned his place in the ranking. The negative parties include an overdose in which arterial pressure can be seriously reduced and the heartbeat, the occurrence of other adverse reactions, from various organ systems, is also required to be very careful to apply amlodipine in patients with hepatic insufficiency and aortic stenosis.
This drug also relates to ACE inhibitors, but is a more modern medicine. Standard dosage tablets - 2,5mg, 5 and 10 mg. Preshaurium is effective in the treatment of hypertensive disease of any severity, which is an obvious advantage. It reduces both systolic and diastolic pressure. This drug is also capable of a single dosage to maintain a hypotensive effect during the day. This medicine allows you to return the elasticity of large vessels, and reduce the excessive development of the left ventricle of the heart. Also the drug is shown in treatment ischemic Disease Hearts, and in patients with vascular diseases of the brain for preventing stroke.
Apply the drug is necessary once a day, it is better in the morning, one tablet. The duration of the course and the translation to higher dosages is carried out by the attending physician. The original press in the middle dosage of 5 mg, calculated for the month of reception can be purchased from 350 rubles. for packaging. The drug has many different analogues: perines, perindopril, hypernik, Koveless.
The advantage of pretarium is the ability to apply in the form of monotherapy, that is, being the only drug from high pressure. It can also be appointed together with other means. The negative parties include side effects that are most often manifested by headache, dizziness, noise in the ears, but at the same time directly depended on the dose. Also, the negative parties can be attributed to the rise of blood pressure at the beginning of treatment. Therefore, to control the patient's condition, and the combination of the prescript with other drugs at the initial stage of treatment should a cardiologist.
Finally, it is impossible to forget about popular drugs in the people, which include potassium-saving diuretics. Typically, strong diuretic drugs, such as furosemide or lazix, are able to bring potassium from the body, which is manifested by unpleasant sensations, impaired heart work, pulling convulsions in the calf muscles, especially at night.
Veroshpiron is a drug that brings urine, but the potassium saves in the body, and the action of its more "soft". This original spironolactone is produced by the Hungarian company Gideon Richter, 20 tablets - 25 mg costs about 70 rubles. Take this drug is also under the control of the doctor, but not more than 4 tablets per day.
The advantages of Veroshpiron applies wide spectrum Indications, ranging from arterial hypertension and heart failure and ending with edema and endocrine disorders. Also, this drug acts softly, and the effect is observed on the 3-5 day of treatment. Of the disadvantages - Veroshpiron should be used carefully with many endocrine diseasesAnd in the treatment of hypertension, he cannot be appointed as a single medication, and must be applied together with other drugs.
Irina Zakharova
Symptoms of increased blood pressure (blood pressure) often appear in people whose age is over 40-45 years. It is no secret that it is impossible to fully from the hypertensive disease, and therefore hypertensive throughout their life use pills from increased pressure. Such drugs improve well-being, help to cope with hypertensive crisis and prevent the development of dangerous complications.
Before proceeding with hypertension therapy, it is recommended to study the features of drugs to normalize the blood pressure level.
It is impossible to engage in medicine therapy immediately after increasing the level of blood pressure. It is advisable to take tablets if blood pressure has repeatedly rose to 165/90 or higher, as such high indicators are considered critical. In patients with diabetes, cardiac or renal failure Critical values \u200b\u200bof hell begin with an indicator of 130/80. In such cases, experts advise complex treatmentwhich uses several different drugs. This will help reduce the likelihood of appearance. side Effects During therapy by reducing the intensity of the effects of each of the drugs.
The effectiveness of any drugs from hypertension increases due to proper nutrition. Therefore, during the reception of medicines, it is better to abandon fatty, salted and fried food. It will also have to stop using alcoholic beverages and smoke tobacco products, since these harmful habits negatively affect blood pressure.
Another thing that will accelerate the treatment of hypertensive disease is gymnastics. Regular walks and morning runs contribute to the expansion of vessel walls and decreased blood pressure.
Like any medications, drugs from pressure have a number of side effects that may appear after their use in the treatment of hypertension symptoms. Common complications include:
All listed side effects are not considered deadly and do not increase the risk of patient's death. However, despite this, before the start of drug therapy, it is better to consult a doctor to appoint the most appropriate drugs without side effects.
Before treatment, each hypertensive must familiarize themselves with the drugs that are able to normalize the pressure. It is recommended to know in advance what kinds of drugs are and what they differ from their mechanisms for the body.
For fast deliverance From the signs of pathology, it is possible to use drugs that are able to instantly reduce the intensity of hypertension symptoms. The most effective drugs from this group include Adelphan and Kaptopril. These drugs are available in the form of sucking tablets that are able to normalize hell for half an hour. The main disadvantage of such medicines is a small duration of action. Because of this, you will have to take medicines at least three times a day.
Also to efficient drugs for normalization high rates AD refers "Furosemide" with a diuretic action. With regular use of these tablets, the patient will urinate 2-3 times more often. It is due to the cleaning of the body and the removal of excess fluid normalizes blood circulation.
However, there are other equally high-quality tablets with a rapid action that are often used with high blood pressure therapy. These include:
Sometimes means with a rapid effect to use contraindicated and instead you have to use drugs in hypertension, which are distinguished by extended action. Manufacturers of such tablets specifically prolong them. therapeutic effectto reduce consumption medicines And make treatment more convenient. With medication therapy, it is enough to drink such drugs 1-2 times a day.
Specialists advise to use these means to patients who suffer from the second or third degree of pathology. On the initial stages Development is better to use less effective medication. The course of treatment with pills is at least three weeks to achieve a persistent and longer result.
Among funds with extended action high efficiency The following are different:
With hypertension with complications, it is recommended to be treated with combined means. They are distinguished by the most effective impact on the body, which is achieved due to several current components in the composition. In this case, all elements in the preparation are contained in the optimal therapeutic dosage. Therefore, when using such drugs, people should understand that 2 or 3 different substances will operate on its body.
The list of effective combined funds includes the following drugs:
When using medicines for the treatment of hypertension, many doctors advise to take advantage of the combined method of therapy, since it is precisely such treatment that is considered the most effective. The essence of the method is to use several drugs at once, which relate to various groups.
To get rid of signs of high blood pressure faster, it is recommended to combine beta-blockers with diuretics.
Such a combination of drugs will improve well-being during the week. Also, in the treatment of pathology, you can take diuretics with inhibitors that will complement each other's actions.
Before using the tools from pressure, you need to familiarize yourself with the main groups of such drugs that differ in their mechanism of action. The list includes twelve drugs lowering blood pressure.
Some doctors recommend hypertensive to take drugs that are responsible for blocking adrenoreceptors. Thanks to this impact on the body, the work of the heart slows down, and the signs of arrhythmia are eliminated. However, some patients, after using such drugs, complications may appear in the form of suffocation and bronchial spasms.
Most often, these problems arise in people with diseases of the lungs. Therefore, not all adrenoblays are suitable for patients with diseases of the respiratory organs. In the treatment of hypertension, they can only use the "forewind" and "propran age." These drugs practically do not have contraindications, and therefore they can drink all hypertensive.
Under the influence of calcium ions, the muscles of the vessels are gradually reduced, which is narrowed by their permeability, and blood circulation is worse. This leads to lifting blood pressure and the development of signs of hypertension. Therefore, medicines whose action blocks calcium channels, help reduce blood pressure.
Regular use of such blockers reduces the need of the heart in the air and makes a reduction in myocardium less intense. In addition, the means included in the group of blockers relax the vascular walls and increase the blood flow. With therapy of hypertensive disease, doctors advise to drink "Nimothol", "Isoptin" and "Cinnarizin".
Preparations are used to normalize blood circulation and elimination unpleasant pain sensationswhich may appear due to high pressure. For rapid down Hell uses such antispasmodics as "papazole", "but-shpa" and "dibazole". The composition of these drugs contain components that are able to improve heartbeat and reduce blood pressure by improving the elasticity of vascular walls.
Not only hypertension leads to an increase in blood pressure. There are other pathologies that are often accompanied by an increase in blood pressure. These include disorders of the nervous system, which arise with long depressions, stress or when fear. In such cases, the pressure will be able to normalize only with the help of funds related to the sedative drug group.
With prolonged use of such drugs, the indicators are normalized by expanding the arteries and reduce their tone. The main advantage of nitrates are that they are able to quickly reduce the elevated level of blood pressure.
Before applying such sedatives, it is better to consult a doctor with a doctor to make a patient compatibility with such medicines.
The funds are not distinguished by high efficiency and therefore they drink them in combination pathology therapy or for a single and short-term reduction of blood pressure. People with glaucoma are contraindicated by the use of adrenoblastors, as this will lead to the appearance of complications. Also, drugs can not use people with heart pathologies, neurological diseases and high intracranial pressure.
Among the effective gangliplockers, "Arfonad", "Ebrantil" and "Fentrolemin" are distinguished.
These are universal medicines that are actively used in the treatment of any form of hypertension. A distinctive feature Sympatolithics It is believed that the effect of their reception is noticeable only after a half weeks after the start of the medical course. A persistent decrease in blood pressure after the use of drugs is observed in 30% of patients. The remaining 70% of the hell decreases for a while.
The use of sympatholists contributes to the removal of the stagnant intestinal or gastric juice. Because of this, many experts do not advise drinking pills to people suffering from gastritis or gastric ulcer.
The disadvantages of sympatholytics include side effects that may appear after their use. Often hypertensive complain of pain in the pancreas and in the stomach. In some, due to taking drugs, breast cancer is developing.
Diuretic preparations are used to improve the work of the heart and normalization of blood pressure. It is necessary to use diuretics only after appointing the attending physician, since with improper use, side effects appear.
The advantage of diuretics is that they help to quickly cope with symptoms of hypertensive disease. When treating such drugs, small dosages are applied, since the high dose contributes to the development of adverse reactions and complications.
Doctors advise drinking diuretics quick actionwhich stabilize blood pressure for 20-40 minutes after their use. The course of treatment with diuretic drugs lasts 1-2 weeks.
The use of such funds reduces the activity of the nervous system by stimulating brain adrenoreceptors. Alpha stimulants are contraindicated to people who suffer from stenosis of mitral or aortic valve. In patients with such pathologies, after applying stimulating agents, complications appear in the form of headaches, impaired coordination of movements, general weakness and drowsiness. In rare cases, the reception of alpha-stimulants ends with the development of alzheimer's symptoms.
To prevent serious complications and side effects, advice with the attending physician before applying drugs.
Inhibitors of ACE or byaders are often used in the normalization of high blood pressure. Tablets help to cope not only with hypertension, but also with myocardial hypertrophy, which may appear with high blood pressure. Also, medications are effectively struggling with manifestations of heart failure. ACE inhibitors are used to enhance blood circulation and strengthen the muscles of the heart.
Blood pressure normalization is achieved by reducing the amount of cholesterol in the blood. Elevated level This substance leads to a deterioration in blood circulation and increased blood pressure.
During medication therapy, sartans are often used. Such medicines have a positive effect on blood pressure and cardiovascular system. Preparations included in this group are prescribed to patients with hypertension, ischemic heart disease and cardiosclerosis. Also, sartans have an antiarrhythmic effect and therefore they can be drunk in the treatment of arrhythmia.
Doctors can assign sartans to reduce the likelihood of a stroke, which sometimes appears in hypertensive. Regular use of such medicines protects the brain and normalizes its daily activities.
Antispasmodic agents are distinguished vasodilative actionThanks to which the brain blood supply is improved. They also help to relax the walls of the vessels and get rid of spasms. This is what is considered the main task of antispasmodics. However, there are other functions that perform such medicines. These include:
Doctors advise drinking antispasmodic drugs with patients with heart or vessels, with high fatigue, poor memory and dizziness.
It is known that the deviations of blood pressure indicators appear due to pathologies that affect the work of the heart or blood vessels. However, sometimes an increase in blood pressure is observed due to increased anxiety or stressful situations. Such problems are characteristic of people with vegetative dystonia or with impaired work of the nervous system. In this case, to normalize hell will have to drink sedatives. The effective means of this category include Valerian and Validol. Also improved well-being will help drugs made on the basis of motherboards or mint.
It is recommended that you get in advance that people drink to eliminate the symptoms of hypertension. Among the huge number of drugs from hypertension, several most effective tools. In the list of drugs that should be drunk while decreasing blood pressure, six drugs are included.
This drug to reduce blood pressure is included in the Sartan group. The use of "Lozartan" prevents vessels to narrow, thanks to which the blood flow is improved. The effectiveness of the medication is caused by angiotensin, which is included in its composition.
To get rid of manifestations of hypertension, it is necessary to drink on a tablet "Lozartan" every day. The patient's well-being is fully normalized in a week after the start of drug therapy.
This is a rather effective ACE inhibitor, characterized by almost instant effect. The pressure drops 2-3 hours after taking tablets.
To improve the effectiveness of "lysinopril", it is necessary to determine the optimal dosage. To do this, visit the doctor who will take the diagnosis of pathology and on the basis of the results obtained will determine the daily dose and the duration of treatment. On average, "Lysinopril" drink at least ten days.
Such a means is popular with people who drink combined drugs with high blood pressure therapy. "Renipril GT" is made of hydrochlorostiazide and maleate. These components have a hypotensive effect on the body, improve vessel's passability and reduce blood pressure.
"Renipril GT" is used only in the treatment of adults, since the medicine is contraindicated to hypertensive under 16 years. To get rid of high blood pressure, you will have to drink two tablets daily for two pills.
Among all ACF inhibitors, it is "captopril" with the greatest popularity. This medicine is often used in providing first aid during the exacerbation of symptoms of hypertension. For long-term use, "captopril" is not suitable, since the frequent use of tablets may result in decrease in blood pressure to critical values. To prevent side effects, it is better to drink a medicine under the supervision of a doctor.
Tablets are made from Indapamide, which has a diuretic and vasodilatory action. The regular use of "arithon" contributes to the removal of excess fluid from the body and reduce high blood pressure. Before using the pills, you need to familiarize yourself with their contraindications. "Arifona" can not be used to patients with disturbed work of the liver and kidney. Also from receiving pills will have to refuse to pregnant girls and teenagers.
Another diuretic drug that reduces blood pressure is "Veroshpiron". The tool contributes to the preservation of potassium in the body, which is responsible for the operation of the cardiovascular system. "Veroshpiron" drink only when combined therapy along with other medicines. To use side effects when using tablets, you need to contact a specialist and determine the optimal dosage.
Currently, new generations of drugs are actively produced, which are much more efficient than old drugs. All means last generation Without dangerous side effects, it is helped by faster to eliminate signs of hypertension.
This diuretic remedy reduces blood pressure due to reducing cuts of vessel walls. Also "Indapamide" improves the permeability of the arteries and lowers the load on the heart. If the drug will use the person to whom it is contraindicated, then complications will appear in the form of weaknesses, headaches, numbness of limbs and problems with digestion.
If blood pressure rises due to the increase in the tone of the vessels, the doctors advise to drink "Methyldop". These tablets quickly cope with the manifestations of increased blood pressure, normalize heartbeat and improve blood flow in the brain. The medicine cannot be drinking people who are sick of renal failure, cirrhosis of the liver, hepatitis, or aggravated form of anemia.
Some doctors advise to be treated with such a diuretic as "hydrochlorostiazide". The medicine helps in the treatment of heart pathologies, eductions and hypertension. The advantages of the "hydrochlorostiazide" are that he has no contraindications. He is prescribed even in the treatment of children and adolescents under 16.
To improve the functioning of the cardiovascular system, "Ramipril" is often prescribed. Such pills contribute to improved blood flow, decreased blood pressure and expansion of arteries. Also, the medicine is cleaned by the kidneys from excess liquid and sodium clusters.
"Ranindril" can not be used by young women who feed the children with breast milk, and patients with renal failure.
In the initial stages of the development of hypertension, they are advised to use "Perindopril", which begins to act on the body an hour after consuming. Tablets are effectively fighting with ischemia, heart failure and hypertension. "Perindopril" can not drink pregnant women and people with increased sensitivity to components from the composition.
Lozartan is considered one of the most effective diuretic drugs that are used for hypertension therapy. Tablets can not drink allergies and girls on the last period of pregnancy. In such people after using Lozartan, dizziness, rash and nausea appear.
Doctors advise to use "Teleminsartan" to prevent the development of such complications like angiopathy. This pathology is accompanied by damage to the vessels and the deterioration of blood flow. The drug is actively used in the therapy of heart failure and hypertension. "Teleminsartan" can not use people with allergies and children up to 10 years.
A distinctive feature of the medicine is that, unlike other similar drugs, Amlodipin does not contribute to the development of tachycardia. Regular use of tablets strengthens heart muscles, expands the vessels and lowers increased blood pressure. To drink "Amlodipine" can not be like people with angina, a severe degree of stenosis and allergies.
With hypertension "Felodipin" is an indispensable medicine that quickly reduces high pressure. Such pills can drink not only young people, but also pensioners in age, since "phenleodipine" has no contraindications and side effects.
There are several medicines that people are often used for hypertension. However, it is not worth doing this, since these funds do not help improve well-being.
Tablets are used in the treatment of inflammation and for anesthesia. "Analgin" does not affect the vessels, and therefore he will not help hypertensive.
It may be useful only at the initial stages of pathology. In the treatment of hypertension, complications do not reduce increased blood pressure.
These drugs help only with complex disease therapy. Together with them, sedative or diuretic pills are well combined.
This drug is contraindicated in hypertensive, since with high blood pressure it can provoke complications. Doctors advise to drink "cititone" hypotoniki, which should be raised blood pressure.
Hypertension is a common pathology that worries many people. Before getting rid of it, you need to get acquainted with the list of drugs from high blood pressure and the features of their use.
Probably there is not a single other group of drugs in which there would be so many drugs. In addition, most means have a kind tent of the analogues, which sings among antihypertensive chaos, a common mind-luxurious mind. But the mind of a good cardiologist and professional pharmacist can comprehend and not such a medicinal Elash.
The variety of antihypertensive drugs is largely due to the fact that today, along with modern, the funds continue to be used in which our grandmothers treated. Fortunately, they are rare enough, but, nevertheless, the Trouble in the treatment of hypertension contributes. In addition, it should be borne in mind that in Russian pharmacies you can still easily buy any antihypertensive drug Without a doctor's prescription. This means that the self-treatment of hypertension, which cannot be called otherwise than "forbidden," continues to flourish and bring bitter fruits.
But does there really have a big difference, how and how to reduce the pressure: the main thing is that the tonometer show the norm or the numbers close to it? Of course, there is, and that is why.
The fact is that many antihypertensive drugs lead to a sharp decrease in pressure. This does not most effect on the health of the patient, however there are consequences much more serious. If you constantly take these medicines, the elasticity of the vascular wall, regularly straining and relaxing, decreases. As a result, they develop (or quickly progress) diseases of the heart and vessels - the most dangerous complications of hypertension.
Adelgan and Klonidin and Klonidin are believed to preparations with a sharp vasodilator effect. Less than powerful action on the vessels are cheap bendazole and its combination with papaverine, metamizol and phenobarbital (Andipal). These tools are reduced cardiac ejection and for long use The ECG indicators worsen.
And vegetable hypotensive drugs, for example Raunatin, and not at all consider it seriously: medicines whose age has already exceeded the sixth ten, has long been found a more efficient and safe alternative.
I listed far from all hypotensive drugs that continue to be produced and applied, despite the serious shortcomings and side effects. There are so many of them that I am afraid to confuse the reader finally. It is much easier to name those tools that all over the world are recognized by the preparations of choice for the treatment of hypertension. They relate to six pharmacological groups:
The mechanism of action of each of these groups is varied and quite complicated:
By the way, there is practically no difference in efficiency between them. From a number of drugs, nifedipine and captopril are taken out, which can be taken as ambulance tools for rapid pressure reduction. In addition, diuretics, calcium channel blockers and ACE inhibitors definitely reduce the risk of cardiovascular disasters, the probability of which significantly increases with hypertension.
As a rule, a hypotensive effect lasts 12, and sometimes 24 hours, which allows you to take medicine two or once a day. However, it is not always possible to cope with hypertension with the help of one drug.
Appointing a hypotensive remedy, the doctor should strive to do the minimum dose. If you have to increase the dosage due to an insufficient antihypertensive effect, you should think about the introduction of the second medication - a priori is safe to take two drugs in minimal doses than one in the maximum. According to statistics, more than half of the patients do not reach the target pressure indicators using one tool.
Combined hypertension therapy can be carried out as with the help of ready-made, complex drugs (for example, perindopril + indapamide, leasing + hydrochlorostiazide, etc.) and due to the combination of two different means. However, it is also necessary to combine with the mind - there are standard schemes that have proven their rationality. The World Health Organization proposes to use five combinations:
It should be noted that even the most qualified doctor is hardly from the first visit of the patient will be able to choose the optimal treatment scheme of hypertension. This process is sometimes long and scrupulous. The patient should regularly keep the diary of blood pressure and noted how the reception of drugs affects its indicators. Doctor, analyzing primary results, adjusts the dose or, if necessary, introduces one more tool. So continues until the effect is reached.
The ultimate goal of hypotensive therapy is not fast decline Increased pressure, but to prevent its lifting. In a patient with hypertension, receiving adequate treatment, blood pressure should always remain normally.
In addition, those who are treated correctly, the risk of a heart attack is reduced by 20-25%, a stroke by 35-40%, and heart failure - more than half. So, with modern "pills from pressure", you can continue to rejoice in life, despite the hypertension.
Marina Pozdeev
Photo istockphoto.com
Arterial hypertension is the most common disease of the cardiovascular system. The selection of medications from hypertension requires an individual approach to the patient to the patient, and on the part of the patient - compliance with the discipline regarding the recommendations of the doctor and the regular use of hypotensive drugs. The main goal of therapy is to reduce pressure to permissible values.
Hypertension is a persistent lift of blood pressure above the norm, it can have different severity - light, moderate, heavy. In young people, hypertension occurs most often in the participation of heartbeat, and in adults is usually associated with an increase in arterial resistance. The increase in both of these parameters may be observed simultaneously, in addition, the volume of fluid circulating in the body is affected by the pressure. Two types of hypertension distinguish: primary (congenital) and secondary (symptomatic). Secondary arterial hypertension may arise due to diseases and pathological changes in kidney, with endocrine disorders, cardiovascular diseases and as a result of diseases of the nervous system. However, in most cases, hypertension is idiopathic. Among the risk factors can be transferred as follows: Genetic predisposition, male floor, menopause age, hyperlipidemia and hyperglycemia, lack of movement, stress, excessive use of salt and alcohol, smoking cigarettes.
Hypertension can develop for many years without accompanied by any disturbing symptoms, so it is often diagnosed too late. Chronic hypertension is one of the main reasons for the development of atherosclerosis and its consequences, that is, ischemic heart disease, left ventricular hypertrophy and insufficiency of this organ, ischemic brain stroke and renal failure. Hypertension directly and indirectly increases the likelihood of early patient death. In pregnant women, it is an increased risk for developing fetus and significantly increases the mortality of newborns in perinatal medical centers.
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Treatment with hypotensive preparations and the success of such therapy largely depends on the stage of arterial hypertension. Preventive inspections from the doctor in this process are very important. Treatment of secondary hypertension in most cases is causing, and therefore, such therapeutic measures are needed that will cure the underlying disease, which is the cause of blood pressure growth.
With primary and secondary arterial hypertension, which was not able to cure, as a rule, only symptomatic treatment applies. During the treatment of arterial hypertension, the doctor must individually approach each patient. It is necessary to include drugs with minimal side effects. Consistently conducted medicia treatment gives real chances of elongation of the predicted life expectancy of the patient. Pressure should be reduced gradually. In addition, it is necessary to apply the minimum possible doses of the drug with an antihypertensive effect. Modern preparations of the first choice in the treatment of arterial hypertension: beta blockers, an ACE inhibitor, AT 1 receptor antagonists or calcium channels, diuretics. It is important to apply the appropriate therapy scheme. Often it is necessary to conduct treatment with two or even three drugs at the same time. The patient must constantly monitor the treatment of arterial hypertension, in particular, daily measuring its pressure and recording its values \u200b\u200binto a special diary.
The list of medical preparations that are quite effective in the treatment of hypertension:
Other medications with a mechanism of action to the central nervous system:
Calcium channel antagonists:
In addition, an ACE inhibitor and drugs with vasodilatory action are used:
Diuretics (diuretics) enhance the removal of water and electrolytes with urine. Diuretics play an important role in the treatment of hypertension. It is recommended as a monotherapy of hypertension, especially elderly people. Extremely valuable is the ability to conjugate diuretics (thiazide) with other drug hypotensive drugs.
Loop diuretics are diuretic preparations of the greatest efficiency (there is a linear relationship between the dose of the drug and its effect). Cause strong diuresis.
Loop diuretics can be used in the treatment of hypertension, but it is necessary to take them with caution, since their use can lead to acute hemodynamic disorder (when the increase in diuresis is too sharp). The side effects of this group of drugs include:
Disorders from the central nervous system (headaches, dizziness, weakness, drowsiness, confusion, consciousness), less often - paresthesia and hematological disorders.
Furosemid - very important representative chain diuretics. Not recommended in long-term therapy, because it acts quickly and briefly. Its action leads to the expansion of vessels and a decrease in the resistance of the vascular system. Furosemide is a first-row preparation for emergency situationsrequiring rapid and significant interference, such as hypertensive crisis. It is sometimes used in the treatment of acute or chronic renal failure with eductions and in chronic congestive heart failure, with arterial hypertension in those patients who do not react to thiazids. Requires simultaneous reception of a large amount of fluid, and sometimes also osmotic diuretics.
Dosage form - Tablets (40 mg), an injection solution (10 mg / ml and 20 mg / 2 ml).
ToramSemid is safer than furosemide, and has more advantages, although it has an almost identical action. Effective after receiving small doses, and the diuretic effect caused to them longer. It is used in the treatment of primary hypertension and cardiac swelling, renal origin.
Dosage form - tablets (2.5, 5, 10 and 20 mg), an injection solution (5 mg / ml), an infusion solution (10 mg / ml).
Stacrinic acid (Acidum etacrynicum). It is more toxic than furosemide. Hearing damage to the use of this acid is often irreparable. Common side effects during its use are gastrointestinal disorders and brain damage. Apply (inward or intravenously) only in the case when the patient has increased sensitivity to the sulfonamide derivative. However, for pregnant women is a safer preparation than furosemide. Currently, practice is used very rarely.
These diuretics cause violations of the water-electrolyte balance of the body, mainly due to inhibiting the inverse absorption of chloride ions, which leads to the sodium and water stop in the tubules. In addition, they significantly weaken the elimination of calcium ions from the body (in contrast to chain diuretics), but reinforce the loss of potassium and magnesium. They have an antispasmodic effect directly on smooth muscles blood vesselsWhat enhances their effectiveness in reducing blood pressure. Well absorbed from gastrointestinal tract. Work longer, but weaker than looped diuretics. There is a limit dose for thiazide diuretics, with an exceedment of which there is no further increase in the beneficial effects of their action, but only the severity of unwanted symptoms. Therefore, you should not increase the dose of these drugs, if there is no positive therapeutic effects.
Hydrochlorothiazide is most often used in the treatment of hypertension in the form of drugs consisting of angiotensin-plating enzyme inhibitors or angiotensin receptor antagonists AT 1. Dosage form - tablets (12.5 and 25 mg).
Chlorortalidon (chlorortalidonum) can be taken every second day, because it works much longer, in contrast to the hydrochlorothiazide (up to 2-3 days).
It is shown for the treatment of arterial hypertension, heart failure and edema. Dosage form - tablets (50 mg), capsules (50 mg).
Indapamidum (Indapamidum). The effect after the use of Indapamide is faster than in the case of chlorotalidone. Its antihypertensive effect is carried out thanks to the inhibition of calcium transport in smooth muscle cells. This drug is shown as monotherapy or combined therapy of arterial hypertension associated with heart failure. Contraindicated to people with diseases of the thyroid gland, because competes with iodine when binding to serum proteins. Dosage shape -thelight coated (2.5 mg), capsules (2.5 mg), prolonged release tablets (1.5 mg).
Claopamidum is used. It is used in the treatment of hypertension and swelling in heart failure, impaired kidney or liver function. There is a component of complex tablets that reduce blood pressure and existing soothing. Dosage form - tablets (20 mg).
These medicines brake sodium ions, potassium ions and the excretion of hydrogen ions. Diuretics of this group cause an increase in urine release without loss of potassium. However, there is a danger of excessive retention of potassium, which can lead to hypercalemia. In addition, potassium-saving diuretics can cause a disorder central nervous system (headaches and dizziness, lethargy, fainting) and gastrointestinal disorders (diarrhea or constipation, nausea, vomiting, abdominal pain).
Available in pharmacies herbal fees and nutritional supplements containing extracts of many types of raw materials of plant origin, which contribute to an increase in the amount of urine allocated.
Components of such drugs / blends are most often extracts:
Preparations of this group have sedative and hypotensive effects, therefore, sometimes used as an aid in the treatment of hypertension:
Used in hypertension middle degree Severity, mainly in combination therapy with other drugs - diuretics or β-blockers. Clonidine should be canceled gradually to prevent sharp pressure growth. The form of the drug - tablets (0.000075 g);
It is used for light and middle forms of arterial hypertension, especially during pregnancy (preparation of the first line in the II and III trimester). It has a moderate effect that decreases with the duration of therapy. As a rule, they take it with diuretics, because it can cause sodium delay and fluid. The form of the drug - tablets (0.25 g).
These effective drugs New generation can be taken, without fear, they are without side effects, in contrast to α 2 -Mimetics:
Preparations of the last generation reduce blood pressure as a result of blocking the catalysis of angiotensin catalyzing enzyme (causes a strong spasm of blood vessels). Used with all types of arterial hypertension.
Side effects and contraindications for the use of an ACF inhibitor: dry cough, disorders of taste sensations, headache, arterial hypotension, diarrhea, muscle spasms, increased sensitivity to light and allergic reactions. Less rarely observed renal failure, and leukopenia. Preparations of this group should not be prescribed to women during pregnancy.
Sartanes (angiotensin receptor antagonists AT 1) are new drugs that selectively block a receptor of type AT 1, which with the help of angiotensin-II causes an increase in blood pressure. It is advisable to take in the treatment of hypertension Lozartan and Valsartan. Used in heart failure therapy and for the prevention of myocardial infarction. It is recommended to patients who do not tolerate the inhibitors of the angiotensin glossy enzyme. Used as monotherapy and combined therapy:
Alisian is a direct inhibitor of Renin, is used to treat primary hypertension. Side Effects and Contraindications: Symptoms such as sleep disorder, poor mood, skin allergic reactions, bronchial irritation, feeling of overflow in epigastria, gastrointestinal disorder, sometimes kidney function and / or liver. Do not recommend it to pregnant women and nursing mothers. The form of the drug - tablets coated with film shell (0.15 and 0.3 g). Combined therapy: Tablets coated with film shell + amlodipine, hydrochlorothiazide.
Phenoldopam is an agonist of DA1 serotoner-engineer receptors, as a result of its activation, the expansion of arterial vessels is caused, which leads to a decrease in pressure. It is used intravenously in moderate and severe cases of arterial hypertension and in situations requiring a sharp decline in blood pressure. It can be successfully used by patients with simultaneous renal failure, as it improves their perfusion. The effectiveness of the hypotensive action is comparable to the action of nitroprusside sodium.
In prevention and as auxiliary means with light hypertension, you can use all kinds of herbas-based drugs or spices (they include the field of field, Parsley ordinary, juniper fruits), which work on the same principle as diuretics, but are not Pharmaceutical medicines.
Arterial hypertension is one of the most common and serious pathologies of the CSS, characterized by a steady increase in blood pressure above 140/90 mm.rt. Doctors call this disease of the epidemic of 21 centuries.
Despite the fact that methods and drugs for the treatment of the disease exists abound, it remains one of the most insidious and dangerous. It is determined by the fact that the first stage of pathology proceeds asymptomatic.
Arterial hypertension can be both independent illness and develop against the background of other ailments, in particular renal.
The therapy of the disease must be timely and appropriate. Ignoring the manifestations of the disease is fraught with serious complications.
It is not necessary to engage in self-medication and take pills from pressure without appointing a doctor. In this article, you will familiarize with the basic principles of the treatment of arterial hypertension and find out which drugs are most effective.
As mentioned, the development of pathology is slow. For a fairly long period of time, a person may not even guess its presence.
The emergence of arterial hypertension may be due to:
The main manifestation of pathology is a persistent increase in blood pressure.
Together with the progression of the disease, the appearance of symptoms indicating the defeat of other systems:
If such symptoms appear, you should not hide a visit to the doctor. Do not self-medicate and do not take any medicines without the permission of the doctor. Remember, a steady increase in pressure requires integrated and long-term treatment. Do not treat the disease at home by folk remedies.
Drugs from plants are certainly effective and with appropriate use they will help in the treatment of illness. But their reception must be approved by the doctor. In addition, the preparations from herbs can be taken as an additional treatment. Pipe tablets can assign an exclusively qualified specialist.
The purpose of the treatment of arterial hypertension is to reduce the risk of defeat "targets" (heart, brain, kidney), since it is these bodies that suffer from high pressure most.
In the initial stages of pathology, as a rule, non-medical methods of therapy are used:
If the above methods are ineffective or ineffective, doctors prescribe medication.
Today in pharmacies a large number of hypotensive drugs that contribute to the normalization of blood pressure and improvement are sold general status and well-being. Different trade names can produce tablets to reduce pressure with the same active component.
To understand them with an ordinary person who does not have medical education is difficult. The main groups of drugs appointed for pathology therapy include: diuretics or diuretic, ACE inhibitors, sardans, beta-adrenoblastors, calcium antagonists, myotropic spasmolytics, nitrates, gangliplockers, sympatholites.
It is important to understand
Arterial hypertension is not the only reason for increased pressure. Symptomatic hypertension is also distinguished when the increase in pressure is one of the symptoms of any disease.
In such cases, the elimination of this state automatically entails the stabilization of the pressure. So, for example, take a stressful situation at which the symptoms are activated and an increase in blood pressure.
Peace, sleep or application soothing drugs It helps to eliminate negative emotions and pressure normalization. A similar picture is observed in painful sensations. Only in this case the reception of narcotic or non-nucleic analgesics is prescribed.
High blood pressure, especially if it is persistent, requires differential diagnosis, as well as expedient treatment. Only a qualified specialist can assign the reception of certain pills from pressure.
One of the most dangerous complications of arterial hypertension, characterized by strong headaches, nausea, soreness in the heart, tinnitus, shortness, rapid heartbeat - hypertensive crisis. This condition is very dangerous, as it can cause an increase in intracranial pressure and development of brain edema.
If the crisis appears, the patient must have emergency assistance.
From how timely it was rendered, the patient's condition will depend on:
Several groups of drugs that contribute to stabilization of pressure are isolated, each group has a special mechanism of action:
The modern pharmaceutical market presents a variety of pills to reduce pressure. However, it is possible to choose and appoint one or another drug by only a qualified specialist. Do not self-medicate, you can harm yourself.
Moreover, do not cost to slow down at a visit to the doctor when a malfunction in the work of the body, in this case, the heart. Resistant high blood pressure is fraught with the development of a hypertensive crisis, and with it and an increase in intracranial pressure.
For the treatment of pathology can assign the use of various forms of medicines. Therapy of arterial hypertension must be combined. Often, the reception of the tablets to reduce pressure, as well as intravenous injections.
As already mentioned, at the initial stages of the disease, therapy is mainly not medicated.
To reduce pressure, appoint the following drugs:
It is impractical to take for therapy of this agence Preparations Rowolphia. These pills to reduce pressure refer to the very first applied to therapy of this pathology. The most popular of them - Raunatin and Rezpin.
The hypotensive effect after receiving the tablets is manifested very slowly. As a rule, the therapeutic effect occurs after a half or two weeks after the start of treatment, and only in ¼ patients comes a clinically significant decrease in blood pressure.
That is, these funds cannot claim the role of effective modern hypotensive drugs. In addition to the fact that drugs are considered ineffective, their reception is fraught with the development of serious side effects: depressive disorders, drowsiness, arrhythmias, impotence, bronchospasm, ulcerations of the gastrointestinal tract, breast cancer and pancreas.
In this regard, some countries have forbidden the production of drugs, which contains reserpine.
Often, appoints:
Hypertension therapy is a long and labor-intensive process. There is a considerable amount of drugs from hypertension without side effects. However, even the reception of such harmless drugs can prescribe an exclusively qualified specialist.
In order to relieve a hypertensive crisis or an attack, the reception of safe high-speed drugs of a new generation, contributing to the instant reduction of blood pressure and the normalization of the pulse. Often for emergency measures prescribe drugs from hypertension without side effects of ACE inhibitors.
The active components of drugs contribute to a decrease in blood flow to the heart, as well as the risk of thickening of the heart muscle. They are aimed at preventing the development of stroke. Reception of any drug is prescribed purely individually. Often, the reception of the following means is appointed: captopril, Kozoten, Edita, Enama, Quina, Khortila, Dotroton, Cylazospill.
Modern drugs to reduce blood pressure are effective drugs of a new generation. Sometimes people suffering from pathology are trying to choose a means of themselves. Such actions may cause crying consequences.
Everyone medication It has its own features and contraindications. There are no exceptions and drugs from pressure. Assign an appointment of a modern drug to reduce blood pressure can only doctor. Funds, diagram and treatment course is selected individually.
Often, doctors prescribe the reception of the following drugs:
Modern preparations for reducing blood pressure are effective and highly efficient. However, they do not recommend them without appointment. It is also not necessary to take folk remedies without a specialist's knowledge.
Elderly and old age gives man not only life experience and wisdom, but, unfortunately, also various diseases. Being young, a person is devoting to a career or raising children. Stresses, use is not quite useful products Nutrition - all this worsens health and provokes the development of chronic ailments. With age the organism, in particular the immune system, weakens.
One of the most common diseases in people's older age categories is arterial hypertension. Medications from hypertension for the elderly can prescribe an exclusively attending physician.
Elderly people often have conservative views. And they are common not only to dress up, love for old films and music, but also on the principles of therapy of this ailment.
Medicines from hypertension in the elderly, if you look into their first-aid kit - this is not modern drugs, and forgotten Adelgan, Cloofelin, Citramamon and Corvalol. Some prefer to take folk remedies in the fight against high pressure.
Such an approach to therapy at least incorrect. In addition, our grandparents grandparents are at least most of them believes that drinking medications are necessary when pressure enhanced. This is not true. Medications from hypertension Elderly people need to be taken constantly because they work on the principle of cumulation in the body.
Often, doctors prescribe reception:
Reception prescribed medications should be permanent. If you take the drug from time to time, the smallest thing that can be - no effect. If not to take on time, for example, a beta-blocker may develop a crisis.