Almagel Medical Properties. What is the difference between various types of almagel. How does vacation from pharmacies

10.07.2020 Analyzes

Structure

Active substances:

5 ml (1 dimensional spoon) Suspensions contain aluminum hydroxide gel, corresponding to 218 mg of oxide aluminum, magnesium hydroxide 350 mg paste, corresponding to 75 mg of magnesium oxide.

10 ml (1 package) Suspensions contain: aluminum gel hydroxide, corresponding to 436 mg of oxide aluminum, magnesium Paste 700 mg hydroxide, corresponding to 150 mg of magnesium oxide.

Excipients: Solution of hydrogen peroxide (30%), sorbitol, hydroxyethylcellulose, methylpaultydroxybenzoate, prophylarahydroxybenzoate, butyl phantroxibenzoate, sodium saccharium, propylene glycol, macrogol 4000, lemon oil, ethyl alcohol 96%, purified water.

Description

white or almost white suspension. When stored on the surface, a layer of transparent liquid may be released. With energetic shacking of the contents of the bottle, the homogeneity of the suspension is restored.

Pharmacotherapeutic group

PBX code - A02AV10. Antacid agents, aluminum compounds.

Almagel is a drug that reduces the increased acidity of the gastric juice. It is a balanced combination of aluminum and magnesium hydroxides, which are insoluble and almost do not enter the body. Almaty is rendered local action on the mucous membrane of the stomach, protects it from irritating acids and other harmful substances And food, reduces pepsin activity. The drug reduces increased acidity in the esophagus. It has anti-inflammatory and astringent effect on the mucous membrane of the esophagus, stomach and duodenal gut. The auxiliary substance sorbitol has a weak windy and moderate choleretic effect, as well as a moderate laxative effect.

Indications for use

Symptomatic treatment of diseases of the digestive tract, accompanied by increased acidity of gastric juice: esophagitis, hernia of the esophageal hole of the diaphragm, gastroesophageal reflux disease (GERD), acute and chronic gastritis, touring, ulcerative disease The stomach and duodenal intestine, post-examination gastritis and gastroanastomozit in the presence of gastroesophageal reflux (heartburn). Prophylactically to reduce the irritant and ulcergogenic action of some drugs on the mucous membrane of the esophagus, the stomach and duodenal estate (for example, corticosteroids, nonsteroidal anti-inflammatory means).

Contraindications

The use of the drug Ashiagel is not recommended with increased sensitivity to the components of the drug, the usual constipation, alzheimer's disease, with severe pain in the abdomen of unspecified genesis, if suspected acute appendicitis, the presence of ulcerative colitis, colostomy or ilostomy, in chronic diarrhea, hemorrhoid, severe renal failure, hypophosphatemia, during breastfeeding, children under 10 years old.

Cautions when applied

When using this medicinal product, keep in mind the following:

In patients with severe constipation; In case of pain in the stomach of unclear origin and with suspected acute appendicitis; in the presence of ulcerative colitis, diverticulosis, colostomy or ilostomy (increased risk of developing disorders of water electrolyte balance); chronic diarrhea; exacerbation of hemorrhoids; with a change in acid-alkaline equilibrium in the body and especially in the presence of metabolic alkalosis; under cirrhosis; with decompensated congestive heart failure; with pregnant toxicosis; with renal failure (danger of hypermagnias and aluminum intoxication).

Patients need to consult a doctor in case of decreasing body weight, the occurrence of difficulties when swallowing or constant sensation discomfort in the abdomen, disorders of the digestion, which appeared for the first time; or when changing the flow of existing digestive disorders.

Aluminum hydroxide can lead to a constation and magnesium hydroxide can lead to intestinal hypocine. The use of this product in high doses may cause or exacerbate the intestinal obstruction and intestinal obstruction, especially in patients with increased risk of such complications, for example, in patients with renal failure or in elderly patients.

The use of antacids containing aluminum, elderly patients should be limited.

For long use The drug must be admitted to the body of a sufficient amount of phosphorus, since aluminum hydroxide binds to phosphates and reduces their absorption from the digestive tract. The removal of calcium with urine increases, which can lead to disorders of calcium-phosphate equilibrium and create conditions for the development of osteomalysis (symptoms - complaints of weakness and pain in the bones).

Aluminum hydroxide can be dangerous when applying patients with porphyria in hemodialysis.

Since aluminum is concentrated in the nervous tissue, the use of aluminum-containing antacids in patients with old age and patients with Alzheimer's disease should be exclusively limited. When taking patients with old age, it is possible to deteriorate the flow of existing diseases of bones and joints.

With prolonged drug intake (more than 14 days), regular medical control is needed and determining the content of magnesium in the blood in the treatment of patients with renal failure.

Interaction with other medicines and other forms of interaction

Please inform your doctor or pharmacist if you take or recently accepted other drugs, even if they were not spelled out.

With simultaneous treatment, other drugs should be taken 1-2 hours before or after receiving Almaty.

Almagel reduces the acidity of gastric juice, and this may affect the action of a large number of medicines while receiving.

Almagel Reduces the absorption of digoxin, indomethacin, salicylate, chlorpromazine, phenytine, reserpine, H2-blockers (cimetidine, ranitidine, Famotidine), lansoprazole, β-adrenobloclars (for example, atomolol, metoprolol, propranolol, chlorohin, cyclin, dyphlunisale, diphosphonates, quinolones ( Ciprofloxacin, norfloxacin, offloxacin, enocusacin, greasyxacin), azithromycin, cefpodoxy, pivampicillin, rifampicin, indirect anticoagulantov, barbiturates, fexophenadin, sodium fluoride, dipyridamole, zombitabine, bile acids (minodeoxychole and ursodeoxycholic acids), penicillamina, lansoprozole, glycosides of vypsydens, iron salts, lithium, chinidine drugs, phenothiazine drugs, tetracycline antibiotics, lincoosamides, phosphorus drugs, Anti-tuberculosis drugs (ethambutol, isoniazide (for oral administration), chloroocyne, GShococorticoid drugs (interaction with prednisone and dexamethasone), kaykeshelate and ketoconazole.

With simultaneous intake of intestinal preparations, the increased alkalinity of the gastric juice can lead to the accelerated destruction of their shell and cause irritation of the stomach and duodenal intestine.

Almagel may affect the results of some laboratory and functional research and tests: it reduces the level gastric secretion and thus changes the results of a functional study of its acidity; Changes test results using technetium (TC99), such as bone scintigraphy and some tests for the esophagus study, increases serum level of phosphorus, serum and urine pH.

Application of the drug and eating and drinks

Application during pregnancy and breastfeeding

Before taking any medicines, consult your doctor or pharmacist.

There is no clinical data on the use of Almaty pregnant women. The drug is not recommended during pregnancy, but if the reception of the drug is necessary, the duration of treatment should not exceed 5-6 days, and the drug should be taken under the supervision of the doctor. It is not recommended to appoint pregnant women with toxicosis.

There is no data on the arrival of the active substances of the drug into difficult milk. Almagel can be used during breastfeeding period only after a thorough assessment of the benefit ratio for mother and potential risk for the newborn.

Impact on control ability vehicles and working with machinery

Almagel does not affect the ability to drive the car and work with the technique. The ethanol included in the drug is contained in quantities that are not able to influence the ability to control the car and using the technique when taking the recommended daily doses.

Information about auxiliary substances

The drug contains sorbitol, which allows you to take it with diabetes, but is unsuitable for the treatment of patients with congenital intolerance to fructose, as it may cause irritation of the stomach and diarrhea.

The suspension contains paragirroxybenzoates that may cause allergic reaction (Perhaps a slow type) and very rarely - bronchospasm.

Medicine Contains 2.5 vol.% ethyl alcohol (ethanol), which corresponds to the content of 98.1 mg of ethanol in 5 ml and 196.2 mg of ethanol in 10 ml of the drug. Due to the presence of ethyl alcohol as part of Almagel, this drug should be used with pregnant, nursing, children and patients with liver diseases, epilepsy and with alcohol addiction.

Information about proper use

Method of application and dose

Always take Almagel exactly in accordance with the instructions of this liner sheet. If you are not sure about something, ask your doctor or pharmacist.

Symptomatic antacid treatment

Adults and children older than 14 years

5-10 ml (1-2 dimensional spoons or 1 package) 3-4 times a day. If necessary, a one-speed dose can be increased to 15 ml (3 dimensional spoons). After reaching the therapeutic effect, the daily dose is reduced to 5 ml (1 dimensional spoon) 3-4 times a day or 1-2 package per day for 2-3 months.

Patients with renal failure

During the treatment of patients with impaired kidney function, it is necessary to reduce the daily dose or increase the interval between the techniques, depending on the severity of the renal failure.

Children from 10 to 14 years

Apply in a dose equal to half a dose for adults - 1 dimensional spoon 2-4 times a day or 2 dimensional spoons 1-2 times a day or 1 pack 1-2 times a day.

For prophylaxis

5-15 ml (1-3 dimensional spoons or 1 package) 15 minutes before taking medications with an irritant action.

Before each admission, the suspension must be thoroughly homogenized, shaking the packaging!

The drug is taken in 45-60 minutes after meals and in the evening before bedtime.

If you have the impression that Almaglel acts too weakly or too much, consult with the attending physician or pharmacist.

If you missed the next reception of Almaty, Take it when the time of the next regular reception comes, does not increase the dose.

If you have any additional questions related to the use of this drug, please contact your doctor or pharmacist.

Overdose

If you have accepted a higher dose than you are scheduled, immediately contact your doctor for help!

With a single overdose, there are no other signs of overdose, except for constipation, meteorism, the sensation of the metal taste.

With long-term admission of high doses, the formation of kidney stones is possible, the appearance of heavy constipation, light drowsiness, hypermagnias. Signs of metabolic alkalosis can also be observed: change in mood or mental activity, numbness or muscle pain, nervousness and fast fatigue, breathing slowing, unpleasant taste.

In these cases, it is necessary to immediately take measures to rapidly eliminate the medicine from the body - washing the stomach, stimulation of vomiting, receiving activated carbon.

When symptoms appear an overdose immediately consult a doctor!

Unwanted reactions

Like any drug Almatiel can cause adverse reactionsAlthough they are not manifested at all.

From the gastrointestinal tract:

the appearance of constipation, which disappear when the dose is reduced, diarrhea, color change kALOV MASS.; Nausea, vomiting, stomach spasms.

Laboratory Indicators:

most often in patients with renal failure and in the case of long-term use or reception of high doses of the drug due to hypermagniasia, the hyperapesimiya develops intoxication by aluminum and magnesium; hypophosphatemia (manifestations of which may be loss of appetite, muscle weakness, loss of body weight); Possible hypocalcemia, hypercalciuria.

By kidneys and urinary tract:

nephroll base, violation of the kidney function;

From the immune system:

allergic reactions of local and total type, including itching, urticaria, angioedema edema and anaphylactic reactions, bronchospasm.

From the central nervous system:

with prolonged use of the drug patients with renal failure and patients on dialysis, encephalopathy, neurotoxicity (changes in mood and mental activity), dementia, state disorders under Alzheimer's disease are possible;

From the musculoskeletal system:

osteoporosis with long-term reception of high doses of the drug with a deficiency of phosphorus in food may occur as osteomalysis;

Others:

changes in taste sensations.

With prolonged use of the drug with patients with renal failure and patients in dialysis, thirst manifestations are possible, reduced arterial pressure, hypoxicia, as well as the development of microcitar anemia.

Without recipe.

Packaging

Suspension of 170 ml in polyethylene terephthalate bottles. One bottle in a cardboard pack along with a dimensional spoon on a 5 ml and liner.

10 ml in a multi-layer foil package. 10 or 20 packets in a cardboard pack, along with a sheet-inch.

Manufacturer

Balkan Farma - Trojan Hell, Bulgaria

5600 Troyan, ul. "Kra'rechna" number 1

Tel.: (+ 359) 0670 68 104

Almagel is one of the first antacid drugs in the pharmacological market, produced for over 40 years.

This drug has antacid, adsorbing and gastroprotective properties. The medicine is intended for the treatment of ulcerative diseases of the stomach and duodenum, acute and chronic gastritis, slit hernia and other stomach diseases.

Also used as a light laxative medicine.

Composition and form of release

All 3 types of the drug Almagel have a neutralizing effect on gastric juice, form a protective layer on the surface of the mucous membrane. Thereby protecting the inflamed mucous membrane from the aggressive impact of the gastric juice.

Almagel

The composition of active ingredients:

Aluminum hydroxide;
Magnesium hydroxide.

Features of the drug:

Aluminum hydroxide - When interacting in the lumen of the stomach with hydrochloric acid of the gastric juice, it neutralizes the latter, reducing, thereby the acidity of the stomach. Aluminum hydroxide reduces the secretion of the enzyme of the stomach - pepsin. This property reduces the aggressiveness of the gastric juice.

Magnesium hydroxide - by analogy with aluminum hydroxide, neutralization reacts of hydrochloric acid. Also, magnesium hydroxide has a relaxing effect, thereby neutralizing the action of aluminum hydroxide, which can cause a slowdown in the peristaltics and constipation.

Almagel neo

The composition of active ingredients:

Aluminum hydroxide;
Magnesium hydroxide;
Siemeticone.

What is the difference: this drug contains the same components as an almagel, but it also includes Simetikon. Siemeticone is a drug that prevents increased gas formation. In case of diseases of the stomach and duodenum, there is a violation of the entire digestion process, which contributes to the activity of intestinal microflora and the active formation of gases in the intestine.

Almagel A.

The composition of active ingredients:

Aluminum hydroxide;
Magnesium hydroxide;
Benzocaine.

What is the difference: contains in its composition the same components as an almagel, but additionally contains benzocaine, which has an anesthetic (freezing) effect on the mucous membrane. Thanks to the benzocaine, it is possible to get rid of the pain caused by inflammation of the mucous membranes, the stomach or duodenum.

Indications for use

The drug is mainly prescribed for diseases of the gastrointestinal tract. Among them are the most frequent are:

ulcerative disease of the stomach (Yabzh) and ulcerative duel disease (Yabdk) - the acute period and period of exacerbation;
acute inflammatory disease of the gastric mucosa (gastritis) with a disruption of the acid-forming function;
food poisoning toxins;
ezophagitis - inflammatory disease of the esophagus mucosa;
duodenitis - inflammatory duodenal disease;
enteritis - inflammatory bowel damage;
hernia in the area of \u200b\u200bthe esophageal hole in the diaphragm;
flatulence;
symptomatic treatment of pain syndrome and a sense of discomfort in the epigastric area, which occur after the error in the diet (abuse alcoholic beverages, smoking, addiction to coffee and excessive reception of medicines);
reception for prevention.

The last item will be appropriate in terms of preventing the reuse of ulcers in gastrointestinal Against the background of the use of nonsteroidal anti-inflammatory drugs and hormones (glucocorticosteroids).

Pharmacodynamics and pharmacokinetics

Almagel is an antacid. Antacids are neutralized with hydrochloric acid, which is contained in gastric juice, which makes them effective for the treatment of acid-dependent diseases. The neutralization of acid is also engaged in the other component of the drug - aluminum hydroxide. In addition, the medium contains magnesium hydroxide, which not only reduces the acidity of the stomach, but also eliminates the ability of aluminum hydroxide to cause constipation. Benzocaine has an anesthetic effect, so the drug effectively copes with painful sensations.

Almagel reduces the secretion of pepsin and reduces the activity of the gastric juice, converting aluminum chloride into alumina alkaline salts. The drug acts without the formation of bubbles carbon dioxide, so he does not cause meteorism. In addition, sorbitol has a laxative effect and enhances the bile separation. Stimulating the synthesis of prostaglandins, the means protects the mucous membrane of the stomach. The effect of magnesium hydroxide and aluminum hydroxide reduces the likelihood of inflammatory, erosive-hemorrhagic lesions from the use of irritant drugs.

Aluminum salts are absorbed into the intestines in small quantities, and magnesium ions are 10%, but their blood concentration is practically unchanged. The drug contains both benzocaine, which almost does not have actions on the body, because it is absorbed in minimal quantity. The effect of the almagel means for pain in the stomach occurs after 5 minutes, and its duration depends on the speed of emptying the stomach. So when used medicinal preparation An empty stomach action lasts up to 60 minutes, and after use in an hour from the last meal intake - up to 3 hours.

Instructions for use and reception scheme

AlmaGel

The drug is taken inward. Before each admission, the suspension must be thoroughly homogenized, shaking the bottle.

Treatment

The drug is taken 45-60 minutes after meals and in the evening before bedtime.

Adults and children over 15 years old are prescribed 5-10 ml (1-2 dimensional spoons) 3-4 times a day. If necessary, a one-speed dose can be increased to 15 ml (3 dimensional spoons). Children aged 10 to 15 years are prescribed in a dose equal to half a dose for adults.

After reaching the therapeutic effect, the daose dose is reduced to 5 ml (1 dimensional spoon) 3-4 times a day for 15-20 days.

Prevention

5-15 ml 15 minutes before receiving medicines with an irritant action.

Almagel A.

Inside. For the purpose of the doctor, 1-3 dosage (tea) spoons, depending on the acuteness of the case, 3-4 times a day half an hour before meals and in the evening before bedtime.

In children, the drug is applied strictly to the appointment of a doctor: children under 10 years old are prescribed 1/3 doses for adults, and for children from 10 to 15 years old - 1/2 doses for adults.

In case of diseases, accompanied by nausea, vomiting and abdominal pain, treatment starts with Almaty A, and on the disappearance of the listed symptoms go to the reception of Almaty.

Before taking the bottle should be shaking.

Almagel neo

Adults

Inside, 2 dimensional spoons of suspension with an orange taste 4 times a day after 1 hour after meals and in the evening before bedtime. If necessary, a one-time dose can be increased to 4 dimensional spoons, but the maximum daily dose should not exceed 12 dimensional spoons.

Children older than 10 years

The dosage determines the attending physician - usually 1/2 dose for adults.

The course of treatment is not more than 4 weeks. Before taking a suspension, it is necessary to homogenize, shaking the bottle. It is advisable to take Almagel Neo in an undeveloped form. No fluid intake is recommended for half an hour after receiving the drug.

Side effects

Green Almaglel and Yellow Almaty A In isolated cases, they lead to the development of nausea, vomiting, to the spasm of the stomach, the change in taste, pain in the epigastria and the constation. Listed side effects Quickly eliminate a simple reduction in the dose of the drug. When used in high doses as a side effect, the suspension can provoke drowsiness.

Prolonged use may reduce the phosphorus concentration in the blood, which will lead to the destruction of bones (osteomalacia). In patients with renal failure, Almaty can provoke edema limbs, dementia (dementia) and an increase in magnesium concentration in the blood.

Almaty Neo When admission, medium doses are able to cause allergies, nausea, vomiting, constipation or diarrhea. Application in high doses can lead to the development of the following side effects:

reducing the concentration of phosphorus and calcium in the blood, the consequence of which is the destruction of bones, osteoporosis and a tendency to fractures;
an increase in the concentration of magnesium and aluminum in the blood;
increased calcium concentration in the urine;
calcium salts deposition in kidney channels (neurocalcinosis);
violation of the normal functioning of the kidneys;
encephalopathy.

People suffering from renal failure, in addition to the above-mentioned features, may observe thirst, lowering pressure and reduce reflexes as side effects of Almagel Neo.

Tablets AlmaGel T. Capably provoke the development of side effects only when applying in high dosages. The side effects of pills are thirst, changing the color of feces and constipation.

Overdose

In the case of one-time consumption of increased dosage of the drug Almagel, and there was no other symptoms, except for the metal taste in oral cavity, meteorism and constipation.

With long-term systemic use of the drug in high doses, the following symptoms may occur:

bradycardia;
neuromuscular paralysis;
nausea and vomiting;
changes in ECG indicators;
anuria;
formation of kidney stones;
drowsiness;
numbness I. painfulness in muscles;
severe intestinal obstruction;
fatigue;
oppression of breathing;
reducing the reflex function;
hypoventilation;
renal failure;
coma;
heart failure.

With extremely severe cases, intoxication may occur:

hospitalization;
receiving sorbents;
stomach wash;
artificial stimulation of the vomit reflex;
symptomatic treatment.

Contraindications

All variants of Almagel have, both general contraindications for use and their own individual, characteristic of the specific form of the drug. Contraindications for the use of each form of Almagel are reflected in the table:

Almaty Neo	Tablets AlmaGel	Green Almaty and Almaty A
Chronic renal failure	Increased sensitivity or allergies to Magalland and / or sorbitol	Sensitivity or allergies to the components of the suspension
Low phosphorus concentration in blood		Renal failure
Pregnancy	Age under 12 years	Alzheimer's disease
Alzheimer's disease		Babies under 1 month
Age under 10 years
Congenital fructose intolerance
Addiction to allergic reactions

In addition, Almaty A (Yellow) due to the presence of Benzocaine can not be taken simultaneously with sulfanimide drugs (Biseptol, etc.).

AlmaGel Neo has relative contraindications, in the presence of which it should be used with caution and under careful control over the patient's condition. These relative contraindications are:

breastfeeding period;
liver pathology;
alcoholism;
card and brain injury;
brain pathology;
epilepsy;
age under 10 years old;
teenagers aged 10 - 18 years.

Almagel or phosphhalugel?

On sale in pharmacies you can meet another analogue of Almaty - Phosfalugel. Let's look at what is better to Almagel or Phosphalugel?

Many are confused by medicines, as they are very similar in their composition. That is why it is very difficult to say which of the antacid drugs is better. However, it is necessary to allocate that phosphhalugel has more properties. This allows you to assign it to different areas (not just like symptomatic drug for diseases of the gastrointestinal tract). It can act as an absorbent and enveloping substance.

Unlike the Almagel, phosphhaluugl does not lead to violation of the metabolism of phosphates and calcium. This property allows a longer reception of the drug. In addition, phosphhalugel can be prescribed to pregnant women, breast-age and older patients. However, to say that some drug is better - unambiguously impossible. The treatment of each patient is selected individually to the doctor.

Almagel or Maalox?

Both Almagel and Maaloks are a liquid dosage form - suspension. In addition, the composition of both drugs is almost identical. Both of them contain as the main active component Aluminum and magnesium hydroxide. Therefore, you can choose any drug that more like a person for any reason for a subjective nature.

However, if the pathology of the gastrointestinal tract organs is accompanied by strong and pronounced pain syndrome, then it is better to prefer Almagel A suspension, which has the best anesthetic effect. In the presence of strong gas formation And the bloating of the abdomen is the most preferred option - it is Almagel Neo, which contains a substance that eliminates this particular symptom. If there is no pronounced pain syndrome or gas formation, then you can choose any drug, depending on personal preferences.

special instructions

Long therapy must necessarily be accompanied by food intake rich in phosphorus. The manufacturer is not recommended to take more than 16 dosage spoons per day. If you need to treat such high doses, the course should last no more than 14 days.

The drug can block the absorption of most medications, which negatively affects their effectiveness. The recommended time interval between the attractions of Almagel A and other drugs is 1-2 hours.

Medicinal interaction

Medicines, the effectiveness of which decreases at the reception together with AlmaGel A:

Isoniazid;
glycosides of fastish;
Tetracycline and all tetracycline antibiotics;
iron salts;
antihistamines;
beta blockers;
Phenothiazines;
Ciprofloxacin;
Ketoconazole.

Analogs

Structural analogues for the acting substance:

Agifluix;
Almol;
Alumag;
Almagel A;
Almagel Neo;
Anazid Forte;
Gastracide;
Maaloks;
Maaloks mini;
Rivolox.

Analogs of PO pharmacological group (Antacids):

Calcium Addiction;
Actal;
Alfogel;
AluGustrin;
Anazid Forte;
Antarite;
Bekarbon;
Hastal;
Gasterin;
Gastric;
Gastoromazole;
Gevisson;
Gevisson Forte;
Gelusil;
Gelusil varnish;
Gevently;
Estate;
Dajin;
Calcium carbonate;
Magalfil 800;
Magnatol;
Magistrad;
Magnesium oxide;
Milk of Magnesia;
Sodium bicarbonate;
Sodium bicarbonate;
Realzer;
Renny;
Riofast;
ROCHEL;
Rutacid;
Symalgel VM;
Schiralate;
Talcid;
Tamm;
Tannakompa;
Tisacid;
Topalkan;
Phosphhalugel;
Andrews Antacid.

How much is AlmaGel

Almagel is sold in pharmacies at a different price. It must be remembered that the vibrations of the cost of the same form of the drug depend not only on the pricing policy of the pharmacy network, but also from the manufacturer's company. The fact is that Almagel is produced by various pharmaceutical concerns, such as Sopharma, Actavis and Balkanpharma-Troyan AD. The cheapest will be AlmaGel produced by Bulgarian Corporation Balkanpharma-Troyan AD. However, the quality of suspensions in all manufacturers - about the same, there are no strong differences. Therefore, choosing Almagel, it is better to buy a drug of that manufacturer who are least formed. Since these data may differ from each other depending on the region, it is best to consult a pharmacist who owns information on this issue.

The cost of various dosage forms Almaty for the convenience of comparison and selection is reflected in the table:

Storage conditions

The shelf life of Almagel is 5 years. Store should be kept in a well-closed container in the cool (from 5 to 150c - the optimal storage temperature) and a place protected from light.

Almagel is an antacid drug, intended for therapy of the GCT, which has analogues. Its active substances neutralize hydrochloric acid included in the gastric juice. The preparation includes aluminum hydroxide, which has become the basis for the manufacture of antacid drugs.

Release form - liquid, tablets. The suspension has additional positive properties, sold in three types:

an ordinary almagel (liquid, tablet) contains only the main components (magnesium, aluminum hydroxide);
the means with the additional designation "A" contains benzocaine, which provides an anesthetic effect;
Almagel Neo, in addition to the main components, it contains a simtacone, eliminating excess gases.

All kinds of funds are sold in boxes of different colors: ordinary - in green, "neo" - red, "a" (with anesthetic) - yellow. For tablets, the designation of the Almagel T. Preparation with the addition of "neo" is available in bags of 10 ml, contains an orange flavor.

Almagel action

The medicine has enveloping and antacid effect. All kinds of it contain basic actively active substances. The mechanism of action: they neutralize hydrochloric acid, protect the mucous membrane of the stomach. It warns the formation of ulcers.

At the same time, substances are neutralized, which can negatively affect the mucosa of the gastrointestinal tract. The composition of the medication is enveloped, creates a protective barrier. It helps active substances to distribute evenly, from which a long effect is achieved.

Sodium hydroxide prevents and eliminates constipation. Sorbitol increases the selection of bile. Both substances contribute to the rapid normalization of the chair. The protective layer saves the stomach from the sensation of gravity, excessive production of hydrochloric acid.

The tool cleans pain in the gastrointestinal tract. It is possible to use almagel from heartburn. The effect of the medication begins 3-5 m after the reception. The duration of the effect is from 1st to 2 hours.

Almagel "A" has a longer and strong painkillers. It can be drunk during poisoning. The drug with the assiciency "neo" prevents. Bubbles are destroyed and absorbed into the intestines, and then derived from the body. The medicine can cause side effects, has contraindications. Pregnant doctors are appointed only with short courses.

Indications and contraindications

The drug is not suction, does not cause metabolic disorders. Almagel under heartburn is used during pregnancy. The medicine does not irritate the urinary system even with long use. Indications for use:

intestinal disorders;
peptic disease;
duodenitis;
intestinal diseases;
flatulence;
esophagus hernia;
enteritis;
from gastritis;
colitis;
pain in the stomach after alcohol consumption;
with reflux - esophagitis;
when aggravating chronic pancreatitis;
after the consequences of the wrong diet.

Drinking Almagel is allowed as auxiliary agent in the treatment sugar diabetes (But on the recommendation of the doctor). The drug can be appointed together with others or after receiving non-steroidal anti-inflammatory drugs, glucocorticosteroids.

He can call side effects, for example, the emergence of short-term numbers of the language, nausea. Relative contraindications for use include:

liver diseases;
epilepsy;
childhood from 10 to 18 years;
with breastfeeding;
alcoholism;
brain disease.

Almagel and alcohol are incompatible, disappears therapeutic effect. Other contraindications include individual intolerance to the components, as well as Alzheimer's disease. It is forbidden to drink simultaneously with sulfonamides and with improper work of the kidneys.

Use during pregnancy and breastfeeding

Women arises the question: "Is it possible an almagel during pregnancy?". It is allowed to drink it with caution to take only yellow and green, with gastritis, ulcers, duodenitis. The drug is used standard for adult dosages, but not more than three days. Suspension is drunk for, after overeating. Almagel can be consumed after stress or disturbed diet.

However, pregnant women can not drink it for a long time, you can use only episodically. After receiving a single dose, it is necessary to wait for the effect. You can drink pregnant women only if necessary. Application is not recommended for breastfeeding.

Instructions for use

Instructions for using Almagel: Before taking a suspension, you need to shake up to a homogeneous composition. Courses of treatment different species The drug is somewhat different. For children, individual dosages and method of use are prescribed.

Type of preparation	Dosage and treatment course	How to drink medicine
Almagel Basic and "A"	1-3 teaspoons three times a day. As soon as the state of the intestine is normalized, the drug is used 4 times a day (1 tsp.) Within 2-3 months. The maximum allowable amount of the drug that can be drunk daily - 16 h. If such a dosage is assigned, the course of therapy should not exceed two weeks.	It is used 30 m before meals, in the evening before bedtime. Do not drink with water medicine.
Almagel neo	Daily 2 h. 4 times. In case of complex proceedings, the dosage increases to 4 dimensional spoons. The maximum allowable amount of the drug is 12 h. in a day. Course - no more than a month.	After using the drug, 30 minutes can not be eaten any liquids. Suspension is drinking in an hour after meals. During the course of treatment in the diet, it is necessary to include products containing phosphorus. The last dose of medication is drinking in the evening, before bedtime.
Almagel T.	Daily drink 1-2 tablets, not exceeding 6 times. The course of treatment is 10-15 days.	It is best to use the drug in an hour or two after meals and before bedtime. After using the drug on an empty stomach, the unpleasant sensations that pass within an hour may appear. If the tablets were eaten together with food, the duration of the medication effect will be 2-3 hours.

You can treat an almagel with an ulcer of the stomach and a 12-rosewoman. The remedy is drinking between meals. After him, other medicines are accepted only after 1-2 hours. Almagel with gastritis is used according to the standard scheme.

Recipe for prophylaxis: 1-2 h. 30 m to each meal. With a long period of reception, the means containing phosphorus are additionally discharged. With such symptoms as nausea, vomiting, therapy begins with a yellow packaging medication.

Almagel tablets can not be taken together with other drugs. The interval must be observed - 1-2 hours. During treatment, you need to abandon any alcoholic beverages. They strongly reduce the effectiveness of therapy.

Instructions for use for children

Children Almagel can be given only from monthly age. Some types of drug are shown only from 10 years. Tablets can be given to children only from 12 years of age.

Type of preparation	Dosage and treatment course			How to accept
Maximum application course at high dosages - no more than two weeks
	up to 10 years old	from 10 to 15 years	from 15 years old
Almagel Basic and "A"	0.3-1 h. Three times a day. As soon as the state of the intestines is normalized, the drug is used for 1 time a day (0.3-0.7 h. L.) Within 2-3 months. Maximum dosage - no more than 5 h.	0.5-1.5 h. drug 4 times a day. After elimination of symptoms - daily 0.5-1 h. Maximum dosage - 8 h.	1-3 h. 3-4 times a day. After elimination of symptoms - daily 1-2 h. Maximum dosage - no more than 16 measuring spoons.	Starting from monthly age. The suspension is given 30 minutes before each feeding, before bedtime. Not powdered with liquids.
Almagel neo	contraindica	Daily 1 tsp. 4 times. With severe disease, there is an increase in the drug to 2 teaspoons. Maximum number - no more than 6 hours l. Course treatment is a month.		Allowed from 10 years old. Accepted an hour after meals. After using the drug, it is impossible to drink for 30 minutes. The last dose is drinking before bedtime.
Almagel T.	contraindica	Dosage and courses of treatment, as in adults		Almagel in tablets Children can only be given from twelve years.

Brief Additional Annotation: The interval in 1-2 hours should be resistant between the Almagel and other drugs. With nausea, vomiting therapy begins with a suspension in yellow packaging. After the symptoms disappear, the transition to the basic almagel follows. For prevention, the medicine is taken 30 m before meals. During its use, products containing phosphorus are included in the diet.

Almagel A.- This antacid means in the form of a suspension is local anesthetic.
Almagel A neutralizes free hydrochloric acid in the stomach, which leads to a decrease in the digestive activity of the gastric juice. Does not cause secondary hypersecretion of gastric juice. It has a topistanisive, adsorbing and enveloping effect, reduces the effect of damaging factors on the mucous membrane.
The therapeutic effect after taking the drug occurs after 3-5 minutes and continues on average 70 minutes.
Almagel A. Provides long-term local neutralization of a continuously separated gastric juice and reduces the content of hydrochloric acid in it to optimal boundaries. Aluminum Hydroxide suppresses the secretion of pepsin, neutralizes hydrochloric acid, forming aluminum chloride, which in an alkaline intestinal environment turns into alkaline salts of aluminum. Magnesium hydroxide also neutralizes hydrochloric acid, turning into magnesium chloride. Thus, countering the effect of aluminum hydroxide causing constipation. Magnesium hydroxide and magnesium chloride is resistive to a slight degree and practically do not affect the concentration of magnesium ions in the blood.
Benzocaine has an effective and long-term local painful effect with pronounced pain syndrome.
The composition of the preparation sorbitol contributes to the enhanced selection of bile and exhibits an easy laxative effect, complementing the effect of magnesium hydroxide.
AlmaGel and does not sharply increase the pH of the contents of the stomach, buffers its value from 4.0-4.5 to 3.5-3.8 (physiological value) in the period between receptions. The drug forms a protective layer, providing a uniform distribution on the gastric mucosa of the stomach of active substances and has a long local action without the subsequent formation of carbon dioxide in the stomach, which, in turn, is the cause of meteorism, feelings in the epigastrine region and secondary strengthening of the secretion of hydrochloric acid.
According to the classification of Hodge and Sterner, the drug when oral use Refers to weakly toxic means and does not have embryotoxic, teratogenic and mutagenic effects. In some cases, elevated tendon reflexes in newborns, whose mothers took the drug for a long time. In addition, newborn has the danger of hypermagniasia development, especially with a state of dehydration, therefore, the prolonged use of the drug is not recommended pregnant and newborns.

Pharmacokinetics

Almagel A.- Non-test drug. In compliance with the correct dosing regime and the duration of treatment, it is practically not resistive in the gastrointestinal tract and has a long uniform effect, which does not disturb the electrolyte balance and without creating the risk of alkalosis or other metabolic disorders. It does not irritate the urinary system and during long-term use does not cause alkalosis and the formation of accretions in the urinary tract.

Indications for use

Indications for the use of the drug Almagel A.are: peptic ulcer of the stomach and duodenal intestine in the aggravation phase; acute gastritis and chronic gastritis with elevated and normal secretory function in the aggravation phase; duodenitis; enteritis; hernia of the esophageal hole of the diaphragm; reflux-esophagitis; functional disorders intestines, colitis; discomfort and pain in the epigastrics in the error in the diet, after drinking coffee, nicotine, alcohol; Preventive in the treatment of GCS and NSAIDs.
In complex medical events Almaty A is prescribed with patients with diabetes.

Mode of application

Suspension Almagel A.take inside. For the purpose of the doctor, 1-3 dosage (tea) spoons, depending on the acuteness of the case, 3-4 times / day half an hour before meals and in the evening before bedtime.
In children, the drug is applied strictly to the appointment of a doctor: children under 10 years old are prescribed 1/3 doses for adults, and for children from 10 to 15 years old - 1/2 doses for adults.
In case of diseases, accompanied by nausea, vomiting and abdominal pain, treatment starts with Almaty A, and on the disappearance of the listed symptoms go to the reception of Almaty.
Before taking the bottle should be shaking.

Side effects

In some cases when taking the drug Almagel A.there may be a change in taste sensations, nausea, vomiting, stomach spasm, pain in the epigastric area and constipation that pass after a dose reduction. When using high doses, drowsiness can cause drowsiness.
Long-term treatment with high doses of drug and poor food phosphorus can lead to predisposed patients to the development of phosphorus deficiency in the body, increased resorption and excretion of calcium with urine and the emergence of osteomalysis. Therefore, with long-term reception of the drug, it is necessary to ensure sufficient admission to the food of phosphorus.
In patients with chronic renal failure, except for osteomalysis, edema of limbs, dementia and hypermagnias may be observed.

Contraindications

:
Contraindications for the use of the drug Almagel A.are: increased sensitivity to drug components; pronounced violation of the kidney function; Alzheimer's disease; Early children's age (up to 1 month).
Do not assign simultaneously with sulfonamides due to the presence of benzocaine in the preparation.

Pregnancy

:
It is not recommended to appoint Almagel A.longer than 3 days during pregnancy.
Avoid appointment with nursing mothers.

Interaction with other medicines

With simultaneous use Almagel A. can reduce therapeutic effect Tetracycline antibiotics, histamine H2 receptor blockers, glycosides of dimensions, iron salts, ciprofloxacin, phenothiazines, isoniazide, beta-adrenoblastors, indomethacin and ketochenozol, etc.

Overdose

:
In one-time dose, other signs of overdose except for constipation, meteorism, the sensation of the metal taste are not observed.
With long reception of high doses of suspension Almagel A.possible nephocalcinosis, the appearance of heavy constipation, light drowsiness, hypermagnias. Signs of metabolic alkalosis can also be observed: change in mood or mental activity, numbness or muscle pain, irritability and fast fatigue, breathing slowdown, unpleasant taste sensations.
It is necessary to immediately take measures to rapidly eliminate the medicine from the body by rolling the stomach (induction of vomiting, receiving activated carbon).

Storage conditions

In the dry, cool and dark place at a temperature of 0 to 25 ° C. Optimal storage temperature - from 5 to 15 ° C. Not allow freezing.

Form release

Almaty A -suspension for intake.
170 ml of the drug in a dark glass bottle with an injected plastic cap.
170 ml of the drug in a polyethylene terephthalate bottle with an injected plastic cap.

Structure

:
1 dimensional spoon of suspension Almagel A.contains:
Active substances: algelfrel (aluminum hydroxide gel 2.18 g, corresponding to 218 mg of alumina oxide); magnesium hydroxide (magnesium hydroxide 350 mg paste, corresponding to 75 mg of magnesium oxide); Benzocaine 109 mg.
Auxiliary substances: sorbitol 801,150 mg, HieTelectloose 15,260 mg, methyl aprichedroxybenzoate 10,900 mg, propyl aprichedroxybenzoate 1,363 mg, butyl aphasibenzoate 1.363 mg, sodium saccharite Dihydrate 0,818 mg, lemon Oil 1.635 mg, ethanol 96% 98,100 mg, water purified to 5 ml.

Additionally

:
Interval between reception Almagel A.and other medicines should be 1-2 hours.
It is not recommended to take a drug in doses exceeding 16 spoons per day, or, if applied such a dose, the duration of treatment should be not more than 2 weeks.
With prolonged reception of the drug, it is necessary to provide sufficient admission to phosphorus.

Main settings

Name:	Almagel A.

1 measuring spoon (5 ml) suspension contains 2.18 g almedrat , 350 mg paste magnesium hydroxide , 109 mg .

Additional components: Hyatellaz, sorbitol, water, ethanol, propyl aprichedroxibenzoate, lemon oil, butyl aprichedroxybenzoate, methyl aprichedroxybenzoate, sacryry saccharite dihydrate.

Form release

Almagel A is produced in the form of a white suspension with a specific lemon smell. A transparent layer of fluid can be formed on the surface during long-term storage.

Energetic shaking restores the homogeneity of the suspension structure. In a cardboard package there is a bottle of 170 ml, instruction from the manufacturer and a special dimensional spoon.

pharmachologic effect

Almagel A reduces activity in the process of digesting food, which is achieved by the neutralization of free hydrochloric acid in the cavity of the stomach. Under the action of the medication, the negative impact of damaging, traumatic factors on the mucous membranes decreases. The drug has an enveloping effect that adsorbing action.

Participated benzocaine It has a long, local, painful effect, which helps to stop pronounced pain syndromes in aggressive gastroenterological diseases. For sorbitol The laxative effect is characterized, the component enhances.

The drug is uniformly distributed over the entire surface of the stomach, protecting the mucous membranes and preventing the formation of carbon dioxide causing.

Pharmacodynamics and pharmacokinetics

The components of the medication are not absorbed through the mucous walls and do not fall into the bloodstream. The competent use of the medication does not lead to a violation of electrolyte equilibrium, resorption in the digestive tract and does not provoke development alkalosis disorders.

It was noted that even during long-term therapy, the medication does not provoke the formation of concrections in the urinary system, does not irritate the urinary paths.

Indications for the use of Almagel A

The drug is used in gastroenterology, favorably affecting the mucous membranes of the digestive system.

Main indications for the use of Almagel A:

gastritis ( , );
hernia of the hole of the esophagus in the diaphragm;
duodenitis ;
epigastric pain in coffee abuse, nicotine or alcohol;
errors in the diet;
reflux Ezophagit (casting content);
nSAID and glucocorticosteroid therapy.

Almagel A is prescribed when complex therapy Patients with.

Contraindications

treatment with sulfonamide;
diseases of the renal system;
age limit - until monthly age.

Side effects

stomach spasms;
vomot ;
changing taste perception;
epigastric pains;
nausea ;

Long-term treatment and simultaneous use of food, poor phosphorus, in predisposed patients leads to a pronounced phosphorus deficiency in the body, strengthening calcium resorption, its excretion of the renal system.

In some cases is registered osteomalacia . During treatment, it is recommended to eat food rich in phosphorus. Patients S. chronic diseases The renal system in addition to osteomalysis develops:

female;
hypermagniamia.

Almaty, instructions for use (method and dosage)

Instructions for use Almagel A

The medication is accepted inside 30 minutes before meals and before bedtime. Multiplicity - 3-4 times a day, motherwise dose - 1-3 dosage spoons.

For 10-15 years, the drug is prescribed from settlement ½ adult dose; Children under 10 years old - 1/3.

With gastroenterological diseases, accompanied by epigastral pain, vomiting and nausea therapy begins with Almagel A. , Then go to simple. Packaging Almagel A has a yellow color, and ordinary Almagel is green. Flakes need to be blamed before applying to restore the homogeneous suspension structure.