What is acidosis, how to treat him? Metabolic acidosis: symptoms, causes, treatment excited acidosis

17.09.2020 Recipes

Acid-alkaline balance is regulated by the systems of the body, which allows the latter to function normally. In the occurrence of acidosis, we are talking about the development of acid disorder towards the increase, which is the main symptom. Causes make it possible to determine the treatment. The metabolic acidosis is considered separately.

If the body increases the amount of acid, then the acidosis is developing. The reason is the insufficient removal of its body and oxidation. Also contribute to this intestinal disorders, starvation and feverish condition, which leads to formation in the urine of acetoxus acid, acetone, a comatose state in difficult cases.

Site site allocates several types of acidosis:

  • Compensated type.
  • Subcompensated type.
  • Noncompensated type.
  • Gas with violation of light ventilation and inhalation of a large amount of CO2.
  • Negazova - divided into:
  1. Metabolic - accumulation in the tissues of acidic products that are destroyed in the body.
  2. Optional - lack of radiating with non-volatile acids and an increase in base loss gasts.
  3. Exogenous - the receipt of a large number of elements involved in the formation of acids.
  4. Mixed.

Metabolic acidosis

The most common type of acidosis is metabolic. With this form, a lot of acid is produced, which in very small quantities is displayed.

Metabolic acidosis is divided into types:

  • Diabetic ketoacidosis, in which an excess of ketone bodies in the body is observed.
  • Hyperchloremic acidosis is formed by loss of bicarbonate, for example, after diarrhea.
  • Lactoacidosis is the accumulation of lactic acid due to alcohol abuse, large physical Loads, malignant tumors, hypoglycemia, use of some medicines, anemia, convulsive syndrome etc.

Metabolic acidosis manifests itself in the following symptoms:

  1. Stunned, comporant or inhibited state.
  2. Student breathing.
  3. Shock and, as a result, death.

This type of disease is diagnosed by analyzing blood to acid-alkaline balance. Treatment is aimed at eliminating the root cause. Sodium bicarbonate or sodium bicarbonate solution is intravenously introduced inside. So that there is no fatal outcome to which metabolic acidosis leads, it should be treated.

Acidosis lactic acid

The lactic acidosis is another common disease in which there is a significant accumulation of lactic acid. Type A is marked with explicit tissue anoxy. Type in practically does not manifest itself.

Type A manifests itself more often. The type in manifests itself very quickly, the reasons for which scientists have not yet been reliably identified.

The type A of lactic acid acid is evolving due to:

  1. Diabetes.
  2. Epilepsy.
  3. Convulsive states.
  4. Hodgkin's diseases.
  5. Diseases of liver and kidney.
  6. Neoplasia.
  7. Myeloma.
  8. Infections.
  9. Leukemia.
  10. Bacteriamia.
  11. Generalized lymphoma.

The type in the lactic acid of acidosis develops due to the effects of pesticides, toxins and drugs.

Causes of acidosis

Preservation of normal acid-alkaline balance It is an important factor as the absence of any infectious diseases. The main causes of the occurrence of acidosis are a lifestyle, a short-lived day of the day and improper nutrition. Also affects the ecology in which a person is abides.

Power plays a very important role. It seems that only acidic products contribute to the development of acidosis. In fact, acid in the body is the result of decay and oxidation of food elements. It is important that the kidneys and lungs worked well at the same time. The kidneys help in bringing non-volatile elements, and the lungs are volatile.

In addition, the organism should not be disturbed metabolism, and should also be absent chronic diseaseswhich provoke the latent flow of acidosis. These include tumors, allergic reactions, neurosis, rheumatism, inflammation of fabrics, etc.

Symptoms of acidosis

Acidosis is often manifested by those symptoms that are expressed by the main disease. In a light form, it may not manifest at all. Sometimes it causes nausea, vomiting and fatigue. The heavy form is manifested in the impairment of the frequency and depth of breathing, heart abbreviations and stunning. Also, severe form is observed in the exchange of substances in the brain. This leads to constant drowsiness and coma.

The acute form of acidosis is recognized by the appearance of diarrhea and insufficient blood supply to tissues. Reducing blood flow provokes dehydration, shock, ostly blood loss and heart disease.

In children, acidosis can manifest itself due to the contest of the disease. This affects its development, leads to convulsions and injection of character.

The initial stage can be recognized by:

The aggravation of acidosis is accompanied by the appearance:

  • Reliability of breathing and heartbeat.
  • Problems with digestion: diarrhea, vomiting, nausea, which leads to dehydration.
  • For sugar diabetes There is a smell of fruit in the mouth, among other signs.

    Acidosis and alkalosis

    are abnormal disorders exchange processes in organism. Acidosis is an increase in acid level. Alkalosis is called deflection towards alkalis.

    With compensated form of disease, a change in sodium bicarbonate and coalic acid occurs. In decompensated form, there is a violation of the amount of acids and alkalis in the direction of excess one of the substances.

    Quite often, acidosis arises against the background of non-spiratory causes. This is the accumulation of lactic acid, acetoxus or oxymaacean acid. The accumulation of lactic acid is often noted due to disorders in the work of the heart or lungs (oxygen starvation). The disease is also developing against the background of diarrhea. In this case, the body includes compensatory functions when the balance between acids and alkalis occurs.

    Alkalosis and acidosis affect the work of the body. Breathing changes, the tone of vessels falls, the minute volume of the heart is reduced and arterial pressure. Violated aqueous I. electrolyte balance. Bones lose their hardness, gradually arise changes in the work of the heart.

    Treatment of acidosis

    Since the acidosis does not exhibit practically, the treatment is sent to eliminate the causes of its occurrence. However, the phenomenon itself is not ignored. Acidosis is treated with protein food with a slight form of its manifestation. From drugs prescribed sodium bicarbonate inside with a slight form or intravenously with severe. Calcium carbonate is prescribed if it is necessary to limit the amount of sodium and during hypocalcemia.

    Metabolic acidosis is treated:

    1. Sodium bicarbonate.
    2. Nicotinic acid.
    3. Cocarboxylase.
    4. Riboflavin mononucleotide.
    5. Glutamic acid.
    6. Dichlorocetate.

    In pathologies, the rehydration salt, dimfosphone orally take orally.

    The main emphasis is on proper nutrition. During treatment, the coffee and alcoholic beverages should be abandoned. Fruits, fats of plant origin, berries, fresh vegetables Accepted with white bread, pasta, animal fats. It is actively recommended to take decoction from rice to remove toxins, slags and other harmful elements.

    Forecast

    Acidosis affects the functionality of the whole organism. If the acid-alkaline balance is broken, then other systems are violated. Mostly suffer from heart, lungs and kidneys. However, acidosis often indicates the development of other diseases that affect the violation of metabolic processes. The forecast is fully dependent on therapeutic measures to eliminate the cause and the most acidosis.

    Life expectancy depends on how quickly a person treats acidosis. In some cases, we are talking about a fatal outcome, if the patient does not take any measures.

    Acidosis is developing due to the accumulation of products that are formed when excessive oxidation of organic compounds, when the body does not have time to withdraw them in a timely manner. This is called as internal reasonsand external. Internal factors talk about pathologies of functions of various systemswhich lead to metabolic disorders and accumulation of metabolites formed during oxidation. External reasons include, first of all, inhalation of the air mixture in which is observed increased content carbon dioxide. The hardest complications of acidosis become a shock or coma state. Extremely possible outcome is also possible.

    Regardless of the etiological factor, the acidotic state leads to serious complications. These include:

    • the pathology of the functioning of the brain;
    • thrombotic disorders;
    • lowering the total number of circulating blood;
    • infarction states of various organs;
    • coma;
    • death.

      Classification

      There are several criteria for which it is possible to distinguish the types of acidotic states.

      Development mechanism involves the following options:

      • respiratory acidosis (occurring due to the increased content of carbon dioxide in the air);
      • irregular acidosis;
      • acidosis of mixed gene.

      Non-spiratory acidosis is also divided into:

      • excretory (arising from the pathology of the removal of metabolites due to violation functional state excretory system);
      • metabolic (developing with the accumulation of endogenous acid metabolites in the body);
      • exogenous (arises due to an increase in the concentration of acid metabolites, which, in turn, developed due to excessive admission to the body of certain products).

      Also, acidosis is classified by the size of the essential of the environment:

      • decompensated;
      • subcompensated;
      • compensated.

      If the acidity indicator reaches minimally permissible values \u200b\u200b(below 7.24), this can lead to denaturation of proteins in the body tissues, the destruction of the cell wall, cell death, pathological changes in the functioning of enzymes, which in the aggregate leads to irreparable consequences up to death.

      The reasons

      Acidosis is a pathological condition and is not classified as a separate disease. It arises as a result of action on the body of etiological factors to which include:

      • abuse of diets and starvation;
      • harmful habits are the use of alcohol and smoking;
      • poisoning;
      • pathology of the GTS functions;
      • metabolic disorders (diabetes, fever, blood circulation pathology);
      • tooling a child;
      • oncological processes;
      • dehydration;
      • pathology of the excretory system;
      • hypoglycemic states;
      • insufficient oxygen consumption at shock, anemic states and cardologies of the cardiovascular system;
      • excessive bicarbonate;
      • reception some medicines (calcium chloride, salicylate);
      • pathology of the respiratory system.

      Symptoms

      The symptoms of this disease are quite difficult to differentiate from the signs of other pathologies. The manifestations of the main symptoms include:

      • vomiting and nausea;
      • improving the fatigue of the body;
      • tachycardia;
      • shortness of breath;
      • an increase in blood pressure;
      • disorders of the functioning of the nervous system (loss of consciousness, inhibited states, dizziness, fainting, increased need of sleep);
      • signs of shock.

      Light forms of pathology may not cause the development of a clear clinical picture.

      Diagnostics

      As diagnostic procedures, at this state uses:

      • assessment of blood levels in the blood; For this, blood is closed from the radial artery, deoxygenated blood - only in case of impossibility of the fence of arterial;
      • determination of the pH of the indicator in the urine;
      • determining the level of electrolytes in serum, which allows differentiation types of acidotic states.

      The doctor also examines an inspection and collection of anaman data, which can help in establishing the cause of the pathological condition.

      Treatment

      Since the acidosis is caused by the pathologies of many systems, then for its treatment, first of all, it is necessary to determine the main reason and to send efforts to eliminate it. That is, therapeutic measures are taken with respect to the main disease.

      In metabolic acidosis therapy should include introduction of the missing fluid by intravenous infusion. Heavy forms of the acidotic state should be relocated to the appointment of medicines that contain sodium bicarbonate. Infusion and drinking forms of this drug are able to increase the level of the hydrogen indicator to the required values. Also, bicarbonate must be added to glucose infusions or physiological solution of sodium chloride, the proportions are determined by the degree of metabolic disorders.

      In the manifestation of pronounced signs of a painful state, symptomatic therapy may be appointed. If the acidotic pathology arose as a result of entering into the body of toxic substances, it is necessary to take measures to eliminate them. Sometimes dialysis may be required.

      It is worth noting that it is important to cure the main pathology, which caused the development of acidosis.

      If it is not eliminated by its etiological factors, the acidotic state may occur again, which destructively affects the functioning of all systems internal organs. Therefore, it is necessary not to simply bring the indicator of the pH of the medium, but also to find out and adjust the cause that caused an increase in acidity inside the body. This will avoid unwanted consequences, which include heavy pathologies - shock, comormed states, as well as fatal outcome.

      Prevention

      The emergence and development of acidosis can be prevented if you lead correct image Life. Also should not be allowed situations under which disorders of metabolic processes inside the body are possible. Reduce the likelihood of an acidotic state, if you follow a series of measures:

      • consume sufficient liquid;
      • control the quality of water for drinking, determine stiffness indicators;
      • make a correct diet;
      • in time to treat metabolic disorders;
      • engage physical culturewhich contributes to the improvement of the blood supply to all organs, and also leads to normalization of the respiratory system.

      Forecast

      For timely diagnosis and appointing correct therapeutic measures outcome prognosis of acidosis may be favorable. In cases of a launched state, a number of serious complications may occur, which include shocks and to whom. In rare cases, acidosis leads to a fatal outcome. Therefore, it is important to carry out the necessary diagnostic events, Repeated medical Helpwhich should include bringing the pH to normal.

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    Under the medical term "acidosis" implies the condition of the human body, in which the acid-alkaline balance is broken.

    Causes of acidosis

    The disorder of acid-alkaline equilibrium occurs as a result of insufficient oxidation and removal of organic acids. Generally, W. healthy man These products are removed from the body quickly. In some diseases and states (for example, during pregnancy, with intestinal disorders, starvation, febrile diseases, etc.) they are removed very slowly. In light cases, this is manifested by the appearance in the urine of acetone and acettoacetic acid (such a state is called acetionary), and in heavy (for example, with diabetes mellitus) leads to a coma, shock and even the death of a person.

    Thus, the causes of acidosis, or rather, factors that accompany the development of this state may be:

    • Pregnancy;
    • Hard diets, starvation;
    • Smoking, alcohol abuse;
    • Poisoning and other disorders of work gastrointestinal tract;
    • Diseases characterized by violation of metabolism (diabetes mellitus, feverish states, etc.);
    • Dehydration of the body (regardless of the cause of it caused);
    • Malignant education;
    • Oxygen starvation (with heart failure, states of shock, anemia);
    • Renal failure;
    • Poisoning of chemicals whose metabolism can lead to the formation of surplus acids;
    • Respiratory failure in heavy form (with emphysema of lungs, pneumonia, hypoventilation, etc.);
    • Loss of bicarbonate kidneys;
    • Hypoglycemia (condition characterized by a decrease in blood glucose levels);
    • Insufficiency of blood circulation (for example, with edema of lungs);
    • Reception individual medicinal preparations (For example, calcium chloride, salicylate, etc.).

    It is worth noting that it is not always possible to establish the cause of acidosis.

    Acidoza classification

    By origin, acidosis is divided into:

    • Respiratory (develops due to inhalation of air with a high concentration of carbon dioxide);
    • Non-irregular (due to abundant non-volatile acids);
    • Mixed.

    In turn, irregular acidosis classified on:

    • Selective: develops as a result of a violation of the function of removal from the body of non-volatile acids most often in kidney disease;
    • Exogenous: characterized by already admission to the body increased quantity substances that are converted in the process of acid oxidation;
    • Metabolic: caused by accumulation in endogenous acid tissues due to insufficient binding and / or destruction. The most difficult state.

    By the level of the pH (at a rate of 7.25-7.44), acidosis is divided into:

    • Compensated - the shift of the pH of blood towards the lower boundary of the physiological norm to the mark of 7.35;
    • Subcompensated - a more pronounced shift in the "acid" side - pH 7.35-7.29;
    • Decompensated - decrease in the level of pH less than 7.29.

    In the case when the pH level in the body reaches extremely low (less than 7.24) indicators (actually, as extremely high), denaturation of proteins (i.e., the loss of their natural properties), and the function of enzymes is reduced, cell destruction occurs - It can lead to the death of the body.

    Acidosis can cause such critical states as:

    • Raising blood clotting;
    • Violation of brain functions;
    • Reduction of circulating blood;
    • Critical blood pressure fluctuations;
    • Dehydration;
    • Peripheral thrombosis;
    • Myocardial infarction;
    • Parenchimatous infarction;
    • Coma;
    • Death.

    Symptoms of acidosis

    The symptoms of acidosis are severely differentiated from the signs of various diseases, and in light shapes, they are not associated with a disorder of acid-alkaline equilibrium.

    The symptoms of acidosis in a light form can be:

    • Briefly arising nausea and vomiting;
    • General malaise;
    • Fatigue;

    More heavy conditions Acidoza may be accompanied by:

    • Cardiac arrhythmia;
    • Disorders of the central nervous system: intensity, dizziness, confusion of consciousness, drowsiness, loss of consciousness;
    • Breath;
    • Hyperpnee (increasing breathing depth, and then its frequencies);
    • Greeting heartbeat;
    • Signs of reducing the volume of extracellular fluid (ECZH), especially in diabetic acidosis;
    • Increasing blood pressure;
    • Increasing stunning.

    Heavy acidosis can lead to circular shock developing as a result of disorders of myocardial reductions and the reaction of peripheral vessels on catecholamines.

    Acidose diagnosis

    As mentioned above, the symptoms of acidosis are not specific. In addition, they are very often disguised by signs of the underlying disease, so the diagnosis is not always able to install immediately.

    For accurate diagnosis, patients conduct the following studies:

    • Blood test to determine the pH level in the urine;
    • Analysis of arterial blood for the presence of serum electrolytes;
    • Analysis of arterial blood for determining its gas composition.

    The last two studies allow you to determine not only the availability of acidosis in humans, but also its type (respiratory or metabolic).

    In order to determine the cause of acidosis, a number of additional research may be needed.

    Treatment of acidosis

    Due to the fact that the described condition is the result of the violation of the functioning of the organism systems, the purpose of the treatment of acidosis is to eliminate the factors that have become a starting mechanism. In particular, we are talking about the treatment of basic diseases, pathological conditions or dysfunctions, which provoked a shift of acid-alkaline equilibrium of the body.

    The correction of heavy forms of acidosis suggests:

    • Elimination of provoking factor;
    • Normalization of hemodynamics: improving the rheological properties of blood, restoration of microcirculation, elimination of hypovolemia;
    • Electrolyte exchange correction;
    • Elimination of hypoproteinemia;
    • Improving renal blood flow;
    • Reinforcement of the hydrocarbonate buffer system;
    • Improvement of oxidative processes in tissues by introducing ascorbic acid, glucose, riboxin, thiamine, insulin, pyridoxine;
    • Improving pulmonary ventilation (transition to artificial ventilation - In extreme cases).

    The targeted correction of the acid-alkaline state by administering solutions of buffers is carried out only at a pH level of less than 7.25 (with decomposed acidosis).

    The symptomatic treatment of acidosis implies abundant drinking, intake of soda, as well as the elimination of related signs (malaise, nausea, arrhythmias, increased pressure etc.). In case of poisoning, drugs are prescribed toxic substances From the body, dialysis is carried out in severe cases.

    Treatment of acidosis in children is similar to therapy of this state in an adult.

    Acidosis I. Acidosis (acidosis; lat. Acidus sour + -SIS)

    one of the forms of disorders of the acid-alkali equilibrium of the body; It is characterized by an absolute or relative excess of acids, i.e. substances that give hydrogen ions (protons), in relation to the grounds that attach them.

    Acidosis can be compensated and noncompensated depending on the value of the pH - hydrogen indicator of the biological medium (usually blood) expressing the concentration of hydrogen ions. With compensated acid acidosis, the blood pH is shifted to the lower boundary of the physiological norm (7.35). With a more pronounced shift in the acidic side (pH of less than 7.35), acidosis is considered noncompensated. Such a shift is due to a significant excess of acids and the insufficiency of physico-chemical and physiological mechanisms for the regulation of acid-alkaline equilibrium. (Acid-alkaline equilibrium)

    By origin A. may be gas, negascin and mixed. Gas A. arises due to alveolar hypoventilation (insufficient removal of CO 2 from the body) or as a result of inhalation of air or gas mixtures containing elevated carbon dioxide concentrations. At the same time, carbon dioxide (RSO 2) in arterial blood exceeds the maximum values \u200b\u200bof the norm (45 mm RT. Art.), i.e. occurs .

    Negazova A. is characterized by an excess of non-volatile acids, a primary decrease in the content of bicarbonate in the blood and the absence of hypercaps. Its main forms are metabolic, excretory and acidosis.

    Metabolic A. arises due to the accumulation of excess acidic products in tissues, insufficient binding or destruction; With increasing products of ketone (), lactic acid (lactate-acidosis) and other organic acids. develops most often in diabetes mellitus, as well as in starvation (especially carbohydrate), high fever, severe insulin hypoglycemia, with some types of anesthesia, alcoholic intoxication, hypoxia, extensive inflammatory processes, injuries, burns, etc. Lactat-acidosis is most common. A short-term lactate-acidosis occurs with enhanced muscle work, especially in incredible people, when the production of lactic acid increases and its absence of its oxidation occurs due to the relative oxygen deficiency. Long-term lactate acidosis is observed in severe liver lesions (, toxic), decompensation of cardiac activity, as well as with a decrease in oxygen flow in due to the insufficiency of external respiration and with other forms of oxygen starvation. In most cases, metabolic A. develops as a result of an excess in the body of several acidic products.

    Selective A. As a result of a decrease in the elimination of non-volatile acids, the kidney diseases (for example, in chronic diffuse glomerulonephritis), resulting in the difficulty of removing acid phosphates, organic acids. Enhanced derivation of sodium ions caused by the development of renal A., is observed in the conditions of braking of acido- and ammoniogenesis processes, for example, long use sulfanimide drugs, some diuretic products. The excretory A. (gastroenterical form) can develop with an increased loss of bases through the gastrointestinal tract, for example, with diarrhea, a stubborn vythe of the alkaline sideline, as well as with a long-enhanced salivation. A. It comes to introduce a large amount of acidic compounds into the body, incl. Some drugs.

    The development of mixed forms A. (a combination of gas and various types of negotiane A.) is due, in particular, by the fact that CO 2 diffuses through alveolokapillary membranes by about 25 times easier than 2. Therefore, the difficulty of discharge CO 2 from the body due to insufficient gas exchange in the lungs is accompanied by a decrease in blood oxygenation and, consequently, the development of oxygen starvation with the subsequent accumulation of unsophisticated interstitial exchange products (mainly lactic acid). Such forms of A. are observed in the pathology of cardiovascular or respiratory systems.

    Moderate compensated by A. flows almost asymptomatic and recognized by studying buffer blood systems, as well as urine composition. At deepening A. One of the first clinical symptoms It is reinforced, which then goes into a sharp breath, pathological forms of breathing. The noncompensated A. is characterized by significant disorders of the functions of the Ts.S., the cardiovascular system, the gastrointestinal tract, and other A. leads to an increase in the content of catecholamines in the blood, so when it appears, the increase in cardiac activity, the increase in pulse, increase minute volume of blood, rise. As I deemed, A. decreases adrenoreceptors, and despite the increased content of catecholamines in the blood, cardiac activity is depressing, hell drops. In this case, often arise different kinds Heart arrhythmias, right up to ventricular fibrillation. In addition, A. leads to a sharp strengthening of vagus effects, causing, increasing the secretion of bronchial and digestive glands; Often there are diarrhea. With all forms of A. The dissociation curve of oxymemoglobin is shifted to the right, i.e. The affinity of hemoglobin to oxygen and its oxygenation in the lungs are reduced.

    For the correction of subcompensated metabolic A. In children (pH 7.35-7-7.30), hydrochloride of caocarboxylase, riboflavin mononucleotide, is used, solution nicotinic acid, glutamic acid solution, sodium bicarbonate. Sodium bicarbonate is part of the oral rehydration salt proposed for oral rehydration during acute gastrointestinal diseases. Children over 6-8 years old can be prescribed a solution of dimphosphon; Used in acute and exacerbation of chronic bronchology pathology, diabetes mellitus, ricket-like diseases, etc. Dimphosbon can cause dyspeptic disorders.

    Treatment of heavy, noncompensated metabolic A. (pH 7.29 and lower) requires compulsory infusion of infusion lesheluoric therapy (usually a solution of sodium hydrocarbonate, which is determined by the formula formula). In order to limit sodium intake, trisamine is used to limit sodium hydrocarbonate. Compared with sodium bicarbonate, trisamine is a good diuretic, has a stronger alkalizing effect and reduces the level of RSO 2. It is shown at a pH of about 7.0. However, newborns, especially in premature, it is not recommended to apply it, because It oppresses his breath, causes an intracellular obscure effect, predisposes to the emergence of hypoglycemia and hypokalemia. It should not be applied to children as a base of sodium lactate, which was previously widely promoted as an integral part of the Darrow mixture. For the treatment of lactate-acidosis, dichlorocetate, activating the enzyme complex of pyruvate dehydrogenase, as well as liquipoic acid preparations, is used.

    When appropriate antiacidotic funds, strict control of acid-alkaline equilibrium indicators with the simultaneous definition of the ionogram is required. With metabolic A., arising from rapidly developing pathological processes, the danger of complications from the obsching solutions is greater than the benefit of the rapid normalization of blood pH. First of all, it concerns young children. So, intravenous administration Cocarboxylase having a soft leaning action can cause a sudden stopping of the heart. Hypertensive solutions of sodium bicarbonate, leading to hypernatremia and blood plasma hyperosmolarity, can contribute to the development of intracranial hemorrhages, especially in premature.

    The inkjet administration of these solutions can cause a metabolic, as a result of which the content of ionized calcium in the blood decreases with subsequent Tetania and apnea. Therefore, newborns are expediently corrected by A. Sodium bicarbonate solution. Gas A. Treatment is carried out on the principles of treatment of respiratory failure (respiratory failure) . With a timely manner and systematically conducting treatment, you can ensure normal development of the child.

    II. Acidosis (acidosis; acid- + -oz)

    the shape of the disorder of acid-alkaline equilibrium in the body, characterized by a shift of the ratio between anions of acids and base cations towards an increase in anions.

    Acidosis excretory (a. Excretoria) - A. resulting from significant amounts of foundations or disruption of non-violating acids; to A. in. Related kidney A, and Gastroenterst A.

    The body is a very complex system consisting of various parts: organs, tissues, cells. And if a failure occurred at some level, the functioning of the entire body will certainly be impaired.

    For example, if the number of acids (they are certainly present in tissues, blood) will increase, then the acidosis will arise. And what are his symptoms? And how should be held effective treatment?

    Acidosis is not an independent disease, but a condition that occurs as a result of a disorder of the acid-alkaline balance of the body.

    Each organism contains acids, they are necessary for its operation. And in the normal state, these most acids should be output, which provides balance.

    But if this for some reason does not happen, they will accumulate in the blood, in the urine and even in some organs. This will certainly tell the alarming symptoms. It is worth noting that treatment should be timely, since strong oxidation is not normal, it can lead to sad consequences.

    Several varieties of such a disease are distinguished. For example, if you take a condition for the development mechanism, the following types can be distinguished:

      • Respiratory acidosis occurs due to insufficient removal of carbon dioxide when breathing. It turns out that it accumulates in the blood and changes its composition.
      • Unpiratoric acidosis arises due to the accumulation of non-volatile acids in the blood, which for some reason are not derived, but remain in the body.

    There is also a mixed form at which accumulating and carbon dioxide, and non-volatile acids.

    Uncredit acidosis can also be classified:

    • Metabolic. This is the most common and at the same time complex form at which endogenous acids begin to accumulate in the tissues of the body, violating their functioning. The symptoms are most pronounced, immediate treatment is required.
    • Excretory. It occurs in case of violation of the excretory function of the body, for example, with renal failure.
    • Exogenous. Its main reason is the admission to the body of an excessive amount of such substances, which in the process of processing are converted into acid and begin to accumulate, not the time to be output.

    Depending on the concentration of acids (it is determined by the level of pH) allocate:

    • With the value of the pH level close to the lower boundaries of the norms, compensated acidosis is diagnosed. With this state, a person may not suspect a long time about such changes, but they will be gradually (sometimes for several years) to disrupt the work of the body.
    • With minor exceeding normal values We are talking about subcompensated form.
    • With a significant exceeding the norms, they are talking about decompensated form. Usually, the symptoms are obvious, the consequences can be sad, so immediate and competent treatment is required.

    The reasons

    Such a condition cannot develop unprepaid. There are many negative factors that can provoke an acid-alkaline balance disorders:


    Manifestations

    Symptoms of such a disease like acidosis light form Diseases or at the initial stage can not manifest itself and do not disturb. And sometimes they are expressed only in the signs of the underlying disease, which led to the accumulation of acids and the development of this state.

    But the manifestations are important to recognize on time to begin treatment and avoid heavy consequences, one of which is coma, and later death.

    That's what symptoms should alert:

    Diagnostics

    It is possible to identify acidosis using blood and urine tests, as their composition will certainly change.

    How to treat?

    With such a disease, such as acidosis, immediate treatment is required, since in difficult cases there is a fatal outcome. So if there is alarming symptoms, immediately consult a doctor.

    Here are basic measures:

    1. Elimination of the cause of the state development, that is, the treatment of the main disease or elimination of pathologies. For example, in diabetes, insulin is required. If the ventilation of the lungs is broken, it will be artificially carried out. Drainage of lungs, the removal of sputum (suction) and reception of expectorant drugs will be required.
    2. It is necessary to comply with a specific diet. The patient should use more berries, vegetables, fruits, cereals, vegetable products. And from strong tea and coffee, alcohol, roasted, flour, smoked, pickled, sweet and salty, it is worth abandoning.
    3. Blood should be cleaned of toxins and acids. It may be necessary plasmferres.
    4. In some cases, dialysis is effective.
    5. In severe forms, fluid is introduced intravenously, as well as sodium bicarbonate. If the patient can drink independently, he should do it. Effective by the technique of soda dissolved in water.
    6. If necessary, symptomatic treatment is carried out.

    Acidosis is curable if measures are timely. Health to you!