Rheumatoid arthritis on the ICD 10. Rheumatoid arthritis Seronegative ICD. These include

23.07.2020 Information

The World Health Organization (WHO) has developed a special medical encoding to diagnose and identify medical diseases. Code of ICD 10 - Encoding the International Classification of Diseases of the 10th Review As of January 2007.

Classification of arthritis on the ICD 10

To date, there are 21 class of diseases, each of which contains subclasses with codes of diseases and states. Rheumatoid arthritis The ICD 10 refers to the XIII class "diseases of the bone-muscular system and connective tissue". Subclass M 05-M 14 "Inflammatory processes of polyarthropathy."

Rectic arthritis of the knee joint is the most common rheumatic disease. The disease is characterized by non-aggregate inflammatory education in the bone structure. In some cases, diseases arises as a response to infectious diseases. gastrointestinal tract (Gastrointestinal tract) urinary tract and bodies of the sexual system.

The development of arthritis occurs a month after infection, but a provocative infection that caused this disease is in the human body does not show itself. Men after 45 years are subject to the greatest risk. The progression of the disease can be facilitated by sexually transmitted infections (gonorrhea, chlamydia and other). Women are less likely to suffer from this ailment.

If the infection carrier fell into the body together with food, the reactive arthritis may equally develop both men and women.

Symptoms of reactive arthritis

A characteristic feature of the course of the disease - the symmetry of the lesion of the joints

Reactive arthritis has acute form. In the first week, the patient is observed increased temperature, disorders of the gastrointestinal tract (gastrointestinal tract), acute intestinal indisposition, total weakness. In the future, arthritis symptoms progresses and is classical. At this stage of development, the disease can be divided into 3 species.

  1. There is inflammation of the mucous membrane of the eye (the development of conjunctivitis is possible).
  2. Paints in the joints are becoming more stronger, while the motor activity is reduced. In the affected infection areas appear notable redness and swelling.
  3. The organs of the urogenital system are inflamed.

Initially, the disease can only hit one knee joint, but subsequently its distribution to other articulations is possible. A pronounced clinic can be insignificant or very strong depending on the human immune system. In the future, the rheumatoid polyarthritis is possible, which is striking larger joints of the lower limbs and the fingers of the foot. Back pains arise at the most severe form of illness.

In rare cases, the disease can affect the central nervous system, give complications on the organs of the cardiovascular system.

Diagnosis and treatment of disease

Today, to confirm whether the patient has reactive arthritis, a whole complex of laboratory research is needed. For examination of the patient, various specialists are involved. It is necessary to undergo an inspection of the gynecologist, a urologist and therapist. The need for examination from other medical professionals will indicate the attending physician. After collecting the results of laboratory tests, data of anamnesis, the identification of clinical manifestations is assigned to the use of certain drugs.

To begin treatment of reactive arthritis is necessary with the destruction of the infectious focus, that is, the pathogens of the original disease. To do this, you need to undergo a comprehensive examination of the entire body. After determining the causative agent, sensitivity to drugs are established. Bacterial infection is treated with antibiotics.

Application antibacterial drugs Recommended on the initial, sharp stage of the disease. In the future, their use becomes less efficient. In some cases, symptomatic treatment is prescribed, in which drugs of a non-steroid group are used, for example, ibuprofen.

So that reactive arthritis does not convey chronic form, Timely treatment is necessary. To make decisions on the reception of patients of those or other drugs should only attending a doctor. It is unacceptable to engage in self-medication.

An important point in preventive measures related to reactive arthritis is to prevent the infectious infection of bone tissue. To do this, you need to stick to the elementary rules of personal hygiene. Avoid embossing intestinal infections into the body, wash your arms before eating and after visiting the toilet, use individual dining devices. Pay attention to the need for the process of heat treatment of foods before use.

From urinary infections Protects the use of a condom at sexual acts. The presence of a permanent partner in sexual life will reduce the risk of the disease. All of the above methods will contribute to the prevention of the ailment.

It is easier to prevent the disease than to treat it. In the event of the first signs of the disease, it is necessary to consult a doctor as soon as possible.

Rheumatoid arthritis - Chronic inflammatory disease of the connective tissue, characterized by its own immune response, systemic nature.

The reasons for the occurrence of the disease are still unknown. Basically, large articular compounds are affected, which are located on the periphery of the body. In the structure of the joint, erosion arise and the destruction of all tissue structures.

Popular rheumatoid arthritis is sick 1% of the population. Women are sick 4 times more often than men. The disease occurs at any age, but most often in 40-50 years.

The main peak of morbidity is 30-35 years old.
After 1 year of the disease, each 3-4 patient has erosive changes in the articular apparatus, which causes a reduction in working capacity.


Causes of rheumatoid arthritis

In the modern world, medical science cannot give an accurate answer, the reason for the occurrence of rheumatoid arthritis.
Risk factors are distinguished, which, to one degree or another, can lead to a change in an autoimmune response to their own mediators.

The main risk factors:

  1. Genetically indirect predisposition. The presence of specific antigens.
  2. Congenital deformation Muscular apparatus.
  3. Imbalance hormonal background During pregnancy, the reception of oral contraceptive and breastfeeding means. Postmenopause in women.
  4. Toxic effect Nicotine on the connecting tissue (tobacco).
  5. Various infectious agents (Mycobacteria, intestinal infections, toxins).
  6. Non-specific agents (injuries, supercooling, abortion).
  7. Specific proteinsgenerated during heat shock.

Rheumatoid arthritis development triggers:

  • Acute infectious diseases.
  • The period of exacerbation of chronic disease.
  • Climate change.
  • Poland.
  • Menopause.
  • Period after childbirth.
  • Injury.
  • Stress reactions.

Types and codes of rheumatoid arthritis on the ICD-10

Rheumatoid arthritis - polymodal disease and different variants of its manifestation are possible. The mechanism of formation and migration of the inflammatory process in the joints is unclear.

Main species

  1. The arthritis form of rheumatoid arthritis:
    • M05.8 - Other seropositive rheumatoid arthritis.
    • M06.0 - Seronegative rheumatoid arthritis.
    • M08.0 - Youth rheumatoid arthritis.
    • M08.1 - Youth Ankylosing spondylitis.
    • M08.3 - Youth Polyarthritis.
  2. Rheumatoid arthritis with the involvement of internal organs or systemic lesions:
    • M05.0 - Felty Syndrome.
    • M05.1 - Rheumatoid disease is lung.
    • M05.2 - rheumatoid vasculitis.
    • M06.1 - Still's disease in adults.
    • M06.2 - Rheumatoid Bursit.
    • M06.3 - rheumatoid nodules.
    • M06.4 - Inflammatory polyarthropathy.
    • M08.2 - Youth rheumatoid arthritis with system start.
    • M35.0 - SHEGREEN Syndrome.

The presented codings of the disease are used in the international classification of diseases

The assignment of one of the codes must be accompanied by a detailed study and on its basis the question of the detailing of the disease according to the ICD-10 is solved. Perhaps a combination of several encodings in one clinical case.

Degree of disease

Since, rheumatoid arthritis is an independent nosological unit, there are degrees of progression of the process, which are based on a number of clinical and instrumental methods Research.

These include:

  1. Clinical stage.
  2. Degree of activity.
  3. X-ray stage.
  4. Functional class.

Clinical Stage

It is installed on the basis of the time interval, from the first manifestations of the disease.

  • Very early stage - Duration of the disease from the first manifestations, not more than 6 months.
  • Early stage - Duration from 6 months to a year.
  • Departed stage - The disease lasts more than 1 year, with the presence of clinical symptoms.
  • Late stage - a period of illness for more than 2 years. Significant damage to small joints and symmetric destruction of major large joints with the formation of multiple erosions.

The degree of activity of the disease

  • Low - Clinical symptoms of scanty, exacerbation up to 1 time per year.
  • Moderate - a pronounced clinical picture, aggravation of painful syndrome up to 4 times a year. Defeat of one target organ.
  • High - permanent pain syndrome. Violation of the movement function. Complications from many physiological systems.
  • Remission - Lack of clinical signs of the disease.

Functional class

Used to assess the employment and self-service function. We are needed to assess the progression of the disease.

  • Functional class 1. - The ability to perform standard physical exertion is stored.
    Casual and professional activity is not broken.
  • Functional class 2. - The ability to perform daily activities, but there is a restriction in the unprofessional sphere.
  • Functional class 3. - Performance of everyday work is preserved, but there are restrictions in professional and non-professional spheres.
  • Functional class 4. - Resistant disorders in self-service. The impossibility of performing professional activity.

Clinical picture

Symptomatics of the disease is made up of several options for the flow of rheumatoid arthritis.

  • Classic option - Multiple lesions of small joints of the brushes and stop. Is symmetrical.
  • Monoarthritis - big joints are affected.
  • Polyarthritis With the damage to small and large joints, after the infectious disease suffered.

For all variants of the beginning of the disease, strict symptoms occurred, which is progressive over time.

Basic symptoms:

  • Total weakness.
  • Hyperhydrosis.
  • Rarely, subfebrile temperature in the evening.
  • Muscular weakness, up to hypotrophy and atrophy.
  • Morning stiffness in small joints of brushes, large joints. It passes after the start of exercise.

As the process progressing, the joints are deformed. There are persistent contractures and limited movement. Change in the joints of the brush, causes deformation by the type of walrus flocks.

Perhaps the occurrence of embracing changes:

  1. Heart damage with the development of rheumatic pericarditis.
  2. Defeat of vessels, internal organs.
  3. Chronic inflammation of the muscular apparatus.
  4. Light lesion (interstitial light fibrosis).
  5. Kidney damage (kidney amyloidosis, glomerulonephritis).
  6. Lymphoenopathy.
  7. System liver damage.
  8. The emergence of complications from the gastrointestinal tract.

Diagnostics

Diagnostic activities are in four major types of research:

  1. Anamnesis.
  2. Physical inspection.
  3. Laboratory research.
  4. Instrumental research methods.

Anamnesis

  • Complaints.
  • The moment of pain or stiffness in the joints.
  • The degree of restriction of work.
  • Recently suffered infectious diseases.
  • Allergic.
  • Heredity.

Physical inspection

  • Every joint inspection in detail.
  • Mobility is rated.
  • Auscultation of the heart and brachycephalus arteries is carried out.
  • Skin covers are inspected, to assess their status.

Laboratory research

  • General blood analysis.
  • Clinical blood test.
  • General urine analysis.
  • Blood biochemistry.
  • Spectrum of lipids.

Instrumental research methods

  • Radiography.
  • CT scan.
  • Magnetic resonance imaging.

Appointment and subsequent assessment of the result of the diagnosis should be engaged in the doctor.

Treatment of rheumatoid arthritis

Modern therapy is the reception of two main groups of drugs:

  1. Fighting preparations (NSAIDs, glucocorticosteroids).They are designed to quickly pain relieve and eliminate the inflammatory response in the joint. Do not affect the course of the disease.
  2. Base preparations (methotrexate, Coursel, Plaquenil, Arava). They are able to delay the development of erosions and the emergence of ankylosis. Thanks to these properties, they retain the functionality of the joints.

It is necessary to modify the lifestyle, with a change in the motor stereotype

Preparations of the new generation

In the modern world, new dosage forms To curb the progression of the disease a bit.

Basic groups of drugs:

  • Aminohinolines.
  • Sulfanimamides.
  • Gold salt.
  • Cytostatic immunosuppressants.
  • Biological modifiers of the immune response.

The choice of drug in the treatment of rheumatoid arthritis should only be engaged in the attending physician, under the control of clinical indicators of blood and radiological picture

Possible complications

Complications of the disease are usually associated with the involvement in the process of internal organs and systems.

The most frequent complications:

  • Rheumatoid pericarditis.
  • Amyloidosis kidney.
  • Amyloidosis of the intestine.
  • Seropositive keratoconuskivitis.
  • Osteoporosis.
  • Increased bone fragility.

Basically complications arise in the late stages of the course of diseases.

Complication with long-term treatment of medication therapy:

  1. Violation of the gastrointestinal tract.
  2. Imbalance hormonal background.
  3. Acute renal, liver failure.
  4. Headache.
  5. Nausea, vomiting.
  6. Constipation, diarrhea.

If complications occur, it is necessary to urgently ask for help in a medical and diagnostic institution

Prevention

Prevention, lies in lifestyle modifications and constant reception medicinal preparations.

Need:

  • Avoid drafts.
  • Wear warm clothes.
  • Resume the reception of NSAIDs, with stressful situations and irrational physical exertion.

Strict rules in prophylaxis does not exist. None of the methods guarantees protection against rheumatoid arthritis.

Tags:

Tactics of application

Classification of arthritis on the ICD 10

(According to the presence of the Russian Federation): seropositive, seronegative

The distinction was carried out in the following types of etiological communication: a) direct infection of the joint, in which the microdis of the ganisms invasize the synovial tissue and in the joint there are microbial antigens; b) indirect infection that can be two types: "reactive arthropathy", when the microbial infection of the body is installed, but in the joint there are no microorganisms or antigens; and "post-infectious arthropathy", in which the microbial antigen is present, but the recovery of the organism is non-unconscious and the evidence of local reproduction of micro organism is absent.

Cyclophosphamide (ampoules of 200 mg), endoxan - Tablets of 50 mg

Physiotherapeutic procedures;

Symptoms of reactive arthritis

Euchness

The second degree is pain intensifying, the restriction of motor activity is such, which leads to a decrease in the working capacity and limitation of self-service.

  1. Symptom complex of the disease included: symmetric lesion of the joints, the formation of deformations, contractures and ankyloses in them; The development of anemia, an increase in lymph nodes, liver and spleen, sometimes the presence of febrile fever and pericarditis. Subsequently, in the 30s-40s of the last century, numerous observations and descriptions of Stilla syndrome revealed a lot of common between rheumatoid arthritis in adults and in children, both in clinical manifestations and in the nature of the course of the disease. However, rheumatoid arthritis in children Ace was different from the disease with the same name in adults. In this regard, in 1946, two American researchers KOSS and BOOTS proposed the term "juvenile (youth) rheumatoid arthritis." The nosological separation of juvenile rheumatoid arthritis and rheumatoid arthritis of adults was subsequently confirmed by immunogenetic studies.
  2. To this variety of remotional arthritis belongs to Stilla Syndrome and Volera-Fanconi. Stilla syndrome is more often diagnosed with preschoolers. It is distinguished by the following features:
  3. Juvenile rheumatoid arthritis is a pathology formed in children and adolescents under 16, in which not only joints can be amazed, but also other organs. A similar diagnosis of the doctor can deliver arthritis in the case of a child, which is ongoing more than 6 weeks. There is a disease not so often. International statistics state that Yura is detected in 0.05-0.6% of children. Children under 2 years old suffer from this ailment extremely rarely. There are sexual differences in the incidence of children. Arthritis is diagnosed more often in girls. The disease is steadily progressing.

NSABS patients with risk of gastropathy and gastrointestinal bleeding (age older than 75 years old, the ulcers of the gastrointestinal tract in history, the simultaneous use of low doses of acetylsalicylic acid and GK, smoking) can be assigned selective or specific COF inhibitors - 2 or (provided with a high individual Efficiency) non-selective COG inhibitors in combination with Mizoprostol 200 μg 2-3 p / day or proton pump inhibitors (omeprazole 20-40 mg / day) in patients with impaired kidney function Treatment NSAIDs should be carried out with extreme caution in the presence of risk of thrombosis patients receiving Selective COF-2 inhibitors should simultaneously continue the reception of small doses of acetylsalicylic acid.

Diagnosis and treatment of disease

For flow:

Alkylating cytostatic; forms alkyl radicals with DNA, RNA and proteins, disturbing their function; It has antiproliferative effect.

Expressed swelling from the very beginning of the disease

With a third degree - the impossibility of self-service, a significant loss of mobility in the joint (joints).

What provokes juvenile rheumatoid arthritis?

Moisustav.ru.

Learning to live with a diagnosis of ICD 10 - rheumatoid polyarthritis

Acute start;

Causes of the occurrence and symptoms of rheumatoid polyarthritis

If the treatment is not started on early stages, there is a high risk that the child will become disabled.

The World Health Organization (WHO) has developed a special medical encoding to diagnose and identify medical diseases. Code of ICD 10 - Encoding the International Classification of Diseases of the 10th Review As of January 2007.

GK systemic use. Recommend to use low (< 10 мг/сут) дозы ГК, что позволяет адекватно « контролировать» ревматоидное воспаление, но должно обязательно сочетаться с базисной терапией Локальная терапия ГК имеет вспомогательное значение. Предназначена для купирования активного синовита в 1 или нескольких суставах. Повторные инъекции ГК в один и тот же сустав необходимо производить не чаще 1 раза в 3 мес. Противопоказания к проведению локальной терапии: гнойный​ Figrogressing, slow-ending (assessment of the pace of development of destructive changes in the joint during long-term observation)

Staphylococcal arthritis and polyarthritis

How to treat rheumatoid polyarthritis?

RA with systemic manifestations (vasculitis, nephropathy).

Massage;

Edema appears when attaching inflammation

By the nature of the appearance in medicine distinguish several forms of arthritis:

The pathogenesis of juvenile rheumatoid arthritis is intensively studied in recent years. The development of the disease is the activation of both cellular and humoral immunity.

Moderate fever;

The level of primary morbidity ranges from 6 to 19 cases per 100 thousand children. It is important that the health forecast depends largely on what age the disease began. The older the child, the worse the forecast. A variety of rheumatoid arthritis is a still disease. The disease occurs very hard, with severe fever, articular syndrome, lesion of the lymphatic system and sore throat. This pathology is also found in adults.

To date, there are 21 class of diseases, each of which contains subclasses with codes of diseases and states. Rheumatoid arthritis of the ICD 10 refers to the XIII class "diseases of the musculoskeletal system and connective tissue". Subclass M 05-M 14 "Inflammatory processes of polyarthropathy."

Rheumatoid arthritis: we treat folk methods

Arthritis

Activities:

200 mg per / m 2-3 times a week before reaching the total dose of 6-8 g per course; Combined pulse therapy; Endocusan in a dose of 100-150 mg / day, supporting dose - 50 mg / day. Methods of operational surgery (injections in the articular cavity).

artrozmed.ru.

Etiology and treatment of juvenile rheumatoid arthritis

Redness Sustava

Features of the disease

Reactive - complication arising from unbearable (unrealized) infections; Pathogenesis of juvenile chronic arthritis

Polyarthritis with involvement in the process of small joints;

Etiological factors

Youth arthritis may occur for various reasons. The exact reason is not yet installed.

Rectic arthritis of the knee joint is the most common rheumatic disease. The disease is characterized by non-aggregate inflammatory education in the bone structure. In some cases, the disease occurs as a response response to infectious diseases of the gastrointestinal tract (gastrointestinal tract), urinary tracts and organs of the sexual system.

  • Uncomfortable Nature
  • I - low, II - moderate, III - high activity
  • Pneumococcal arthritis and polyarthritis
  • Hemorrhagic cystitis, myelosuppression, activation of foci of infection.
  • NSAIDs, cytostatics, hormonal agents, antibiotics, etc. are prescribed from medical drugs. A set of drugs depends on the type and etiology of arthritis. Table 2 shows the treatment of rheumatoid arthritis.
  • Yes, but it may not be immediately
  • Rheumatoid - is a consequence of rheumatic diseases;

The main clinical manifestation of the disease is arthritis. Pathological changes in the joint are characterized by pain, swelling, deformations and restriction of movements, an increase in skin temperature over the joints. Children most often amazed large and medium joints, in particular, knee, ankle, ray-beyond, elbow, hip, less often - small brush joints. Typical for juvenile rheumatoid arthritis is the defeat of the cervical spine and maxillo-temporal joints, which leads to underdevelopment of the lower, and in some cases upper jaw and the formation of the so-called "bird jaw".

Forms of the disease

Increasing and soreness of lymphatic nodes;

Possible etiological factors are the following:

  • The development of arthritis occurs a month after infection, but a provocative infection that caused this disease is in the human body does not show itself. Men after 45 years are subject to the greatest risk. The progression of the disease can be facilitated by sexually transmitted infections (gonorrhea, chlamydia and other). Women are less likely to suffer from this ailment.
  • Arthritis
  • X-ray stage:

Clinical symptoms

Chlorbutin (leykeeran) - Tablets 2 and 5 mg

  • Preparation
  • Yes, but in the later stages of redness may not be
  • Acute - develops after bruises, fractures, strong physical exertion;
  • Symptoms of juvenile chronic arthritis
  • Hepatosplegegaly;

The presence of viral or bacterial infection;

If the infection carrier fell into the body together with food, the reactive arthritis may equally develop both men and women.

  • , Any skin changes near the place of puncture, joint tuberculosis, dry spinal cord, aseptic necrosis of bones, intra-articular fracture, fractures of the joint. Used the following drugs (In large joints, a complete dose of drugs is introduced into the middle size - 50%, in small - 25% dose): methylprednisolone 40 mg Hydrocortisone 125 mg Betamethasone in the form of drugs for injection (Celleston, Flosterone, Diprospan) Pulse - Methylprednisolone therapy leads to rapid, but short-term effect (3- 12 weeks); Not affecting the rate of progression of the process in order to prevent osteoporosis to individuals receiving HC, calcium preparations (1500 mg / day) and cholecalciferol (400-800 IU / day) are prescribed, and in the absence of their effectiveness - bifosphonates and calcitonin (see osteoporosis).
  • I - okolossertovic osteoporosis, II - the same + narrowing of intermediate slots + single erosion, III - the same + multiple erosion, IV - the same + ankylosis
  • Other streptococcal arthritis and polyarthritis
  • Alkylating cytostatic; forms alkyl radicals with DNA, RNA and proteins, disturbing their function; It has antiproliferative effect
  • Principle of action

Symptoms intoxication

Other manifestations

Infectious - caused by viruses or a fungal infection that falls into a joint with blood flow, or through an non-sterile surgical instrument, often leads to the development of purulent inflammation of the knee joint;

  • With a systemic version of juvenile rheumatoid arthritis, leukocytosis is often detected (up to 30-50 thousand leukocytes) with a neutrophilic shift to the left (up to 25-30% of pulicheartic leukocytes, sometimes up to myelocytes), an increase in ESP to 50-80 mm / h, hypochromic anemia, Thrombocytosis, an increase in the concentration of C-reactive protein, IgM and IgG in serum.
  • Anemia;
  • Traumatic damage to the joint;
  • A characteristic feature of the course of the disease - the symmetry of the lesion of the joints
  • Basis therapy
  • Anise functional ability:

  • The high activity of the RA with systemic manifestations, generalized lymphoenopathy, splenomegaly.
  • Principle of action
  • Observed in the case of autoimmune nature of the disease
  • Reiter syndrome is a kind of reactive arthritis;
  • Diagnosis of juvenile chronic arthritis
  • Myocardial damage;
  • Increased insolation;
  • Jet arthritis has an acute form. In the first week, the patient has elevated temperatures, disorders of the gastrointestinal tract (gastrointestinal tract), acute intestinal malaise, general weakness. In the future, arthritis symptoms progresses and is classical. At this stage of development, the disease can be divided into 3 species.
  • Basis therapy should be prescribed to all patients with reliable ra.

0 - Saved, I - Professional ability stored, II - Professional ability is lost, III - the ability to self-service is lost.

Diagnostic events

Arthritis and polyarthritis caused by other refined bacterial causative agents, if necessary, identify the bacterial agent use additional code (

6-8 mg / day, supporting dose - 2-4 mg / day.

  • Destination schemes
  • No
  • Arthritis in Bekhterev's disease, gout (infrequent phenomenon);
  • Suppression of inflammatory and immunological activity of the process.

Polyporosite;

Supercooling;

There is inflammation of the mucous membrane of the eye (the development of conjunctivitis is possible).

Tactics of treatment

The "gold standard" of the basic therapy of the RA remains a methotrexate, which has the best ratio of efficiency / toxicity. Prescribe patients with active RA or having the risk factors of an unfavorable forecast (see above) at a dose of 7, 5-15 mg per week. The term of the effect of 1-2 months. Among the side effects of methotrexate - hepatotoxicity, myelosuppression, so the control of OAK and transaminase should be carried out monthly. Increasing the level of liver enzymes - a signal to a reduction in the dose of the drug or its complete cancellation. Resistant increase in the level of liver enzymes after the discharge of the drug is an indication to the liver biopsy. Taking into account the antifolate mechanism of action shows the reception of folic acid 1 mg / day excluding the days of the application of methotrexate.

Frequency - 1% in the overall population. The predominant age is 22-55 years. The prevailing floor is female (3: 1). Incidence: 23, 4 per 100,000 population in 2001

Mielosuppression.

Possible side effects

SpinaZDorov.ru.

Juvenile rheumatoid arthritis

Symptoms of "Sustav"

Psoriatic arthritis (occurs in 10-40% of patients with psoriasis)

Code of the ICD-10

  • Saving system manifestations and articular syndrome.
  • Raising ESP in the UAC.
  • Hit in the body of protein components;
  • Paints in the joints are becoming more stronger, while the motor activity is reduced. In the affected infection areas appear notable redness and swelling.
  • Hydroxychlorookhin (200 mg 2 p / day or 6 mg / kg / day) - a frequent component of combined therapy of active, especially "early" ra. Hydroxychlorochin monotherapy does not slow down radiographic progression. The effect of the effect of 2-6 months. With long-term treatment, an annual ophthalmological examination is necessary, a study of field fields.
  • Unknown. In the role of "arthritogenic", various exogenous (viral proteins, bacterial superantigines, etc.), endogenous (collagen type II collagen, stress proteins, etc.) and nonspecific (injury, infection, allergy) factors.
  • Due to the fact that the treatment schemes specified in the table are not always effective, several combinations of basic means are used in practice, among which the combinations of methotrexate with sulfasalazine, methotrexate and delagic were obtained. Currently, the treatment is considered the most promising scheme in which methotrexate is combined with anti-liter.

Epidemiology of juvenile chronic arthritis

Preparations of quinoline row (degyl - tablets of 0.25 g)

Classification of juvenile chronic arthritis

Reiter syndrome (according to ICD-10 code 02.3) can develop in two forms - sporadic (pathogen - S. trachomatis) and epidemic (Shigella, Iranseania, Salmonella).

Saving the functional ability of the joints.

Causes of juvenile chronic arthritis

With a subacute of the course of the disease, the symptoms are less pronounced. Initially one joint is affected. It is more often an ankle or knee joint. It can be affected by both 1 joint and several. With the oligoarticular form of the disease, 2-4 joints are affected. Peeling syndrome may not be. In case of medical examination, the swelling and disruption of the joint function is determined. The movement of the patient child is difficult. Liver and spleen of normal sizes. The subacute flow proceeds more favorably and is better amenable to therapy.

Hereditary predisposition;

The organs of the urogenital system are inflamed.

Pathogenesis of juvenile chronic arthritis

Sulfasalazine is particularly shown in the sernegative RA, when differential diagnosis with seronegative spondyloarthropathies is difficult. Starting dose 0, 5 g / day with a gradual increase in dose to 2-3 g / day in 2 reception after meals. Taking into account myelotoxicity of the drug when it long use Oak control every 2-4 weeks for the first 2 months, then every 3 months.

70% of PA patients have AG HLA - DR4, the pathogenetic significance of which is associated with the presence of rheumatoid epitope (section B - the HLA - DR4 molecule chain with a characteristic amino acid sequence from the 67th of the 74th position). The effect of "Dose of Gene" is discussed, that is, the quantitative - qualitative relationship between the genotype and clinical manifestations. The combination of HLA - DW4 (DR B10401) and HLA - DW14 (DR B1 * 0404) significantly increases the risk of developing RA. On the contrary, the presence of ag-stitches, for example, HLA - DR5 (DR B1 * 1101), HLA - DR2 (DR B1 * 1501), HLA DR3 (DR B1 * 0301) significantly reduces the likelihood of the disease of the Republic of Armenia.

Symptoms of juvenile chronic arthritis

In medical practice, there are often cases of lack of effect from treatment (for example, when reactive arthritis, inflammation is not removed even when taking antibiotics in combination with NSAIDs), when patients retain the activity of the disease and the rapid progression of articular deformations.

Diagnosis of juvenile chronic arthritis

Stabilization of lysosomal membranes, braking phagocytosis and chemotaxis of neutrophils, inhibition of synthesis of cytokines.

Objectives for the treatment of juvenile chronic arthritis

  • The clinical picture differs from other species of arthritis, since the accompanying signs of the disease are the lesions of the mucous membranes of the oral cavity, prostatitis (in men), vaginitis and cervicitis (in women). A common feature is inflammation of the eye (conjunctivitis, iridocyclite), which manifests itself in redness of the sclera, the appearance of purulent discharges, eyelidity.
  • Preventing or slowing down the destruction of joints, disabled patients.
  • It is necessary to know not only the causes and symptoms of juvenile rheumatoid arthritis, but also methods for its diagnosis. In the early stages of the disease, symptoms can be expressed weakly, so the diagnosis is often difficult.
  • Violation of the functioning of the immune system.
  • Initially, the disease can only hit one knee joint, but subsequently its distribution to other articulations is possible. A pronounced clinic can be insignificant or very strong depending on the human immune system. In the future, the rheumatoid polyarthritis is possible, which is striking larger joints of the lower limbs and the fingers of the foot. Back pains arise at the most severe form of illness.
  • Leflomoid - a new cytostatic preparation with an antimetabolic mechanism of action, designed aiming for the treatment of RA. Applied at a dose of 10-20 mg / day. The effect develops after 4- 12 weeks. Monitoring toxicity implies control of the level of liver enzymes and the UAC.
  • The basis of the pathological process under the Republic of Armenia lies generalized immunologically caused inflammation in the early stages of the disease, the AG is detected - specific activation of CD4 + - T - lymphocytes in combination with hyperproduction pro-inflammatory cytokines (Tumor necrosis factor, IL - 1, IL - 6, IL - 8, etc.) against the background of the deficit of anti-inflammatory mediators (IL - 4, soluble antagonist IL - 1). IL - 1 plays an important role in the development of erosions. Il - 6 stimulates B - lymphocytes to the synthesis of the Russian Federation, and hepatocytes - to the synthesis of proteins of the acute phase of inflammation (C - jet protein, etc.). FNF - A causes the development of fever, pain, cachexia, is important in the development of synovitis (it contributes to the migration of leukocytes into the joint cavity by strengthening the expression of adhesion molecules, stimulates the production of other cytokines, induces the pro -ugulating properties of the endothelium), and also stimulates the growth of the pannus (granulation tissue penetrating cartilage from synovial tissue and destroying it). An important prerequisite is the weakening of the endogenous synthesis of GK - hormones in the late stages of the Republic of Armenia under conditions of chronic inflammation, tumor-like processes are activated due to the somatic mutation of fibroblast-like synovial cells and apoptosis defects.

Forecast

The conclusion about the need to change the program of therapy doctors are made if the patient was treated for six months using at least three basis drugs.

The initial stage of the RA.

Laboratory research methods

Arthritis of the knee joint should be differentiated from other pathological processes, the most common of which are arthrosis and bursitis. Bursitis, which is inflammation in a synovial bag, an experienced specialist will be easily distinguished from arthritis at the first reception.

Achieve remission.

Prevention of juvenile chronic arthritis

The main methods of diagnosis is:

ilive.com.ua.

Causes, Symptoms, Diagnostics and Treatment of Knee Arthritis

Out of viral infections The most dangerous those that are caused by the Epstein-Barr virus, Parvovirus and Retrovirus. The mechanism of development of the disease is associated with autoimmune violations. When exposed to any unfavorable factor in the body of a child, special immunoglobulins are formed. In response to this, the synthesis of the rheumatoid factor occurs. There is damage to the joints. At the same time, synovial shells and blood vessels are affected, cartilage fabric. Not only joints, but also the edge parts of the bones (epiphysis) can be collapped. The generated circulating immune complexes are spread through the blood vessels in various organs. At the same time there is a risk of developing polyorgan insufficiency.

Etiology

In rare cases, the disease can affect the central nervous system, give complications on the organs of the cardiovascular system.

Gold salts (for example, sodium ahuroyatomalat) are used to treat seropositive ra. Trial dose of 10 mg in / m, then 25 mg per week, then 50 mg per week. As the total dose is achieved, 1000 mg is gradually moving to a supporting mode of 50 mg 1 time in 2-4 weeks. The effect develops after 3-6 months. Among the side effects - myelosuppression, thrombocytopenia, stomatitis, proteinuria, therefore, OAK and OAM are recommended to spend 1 time in 2 weeks.

Evidence of the ineffectiveness of therapy is the negative dynamics of laboratory research, the preservation of the focus of inflammation. In this case, it is necessary for an alternative decision on how to treat arthritis of the knee joint. Medical statistics confirms the positive trend in the use of pulse therapy using hormonal drugs (methylprednisolone intravenously, isotonic solution for three days - three courses are repeated after one month). Methylphosphane is prescribed with caution in combination with cyclophosphane due to the high toxicity of drugs.

2 table. per day first 2-4 weeks, then 1 table. per day long.

Arthritis in children

Reveal changes

First, when ferursite, the knee mobility is slightly limited, secondly, the articular inflammation area has clear contours. When palpation, the doctor quickly determines the boundaries of the inflammatory hearth. As for the arthrosis, the differentiation is more complicated, since these diseases that have absolutely different etiology, there are many similar signs.

Improving the quality of life of patients.

Collection of anamnesis;

Symptoms of the disease

The classification of Yura on the ICD 10 takes into account the type of lesion of the joints. Polyarthritis and oligoarthritis are isolated. The ICD 10 subdivides arthritis on acute and subacute. There is a classification that takes into account clinical symptoms Diseases.

Today, to confirm whether the patient has reactive arthritis, a whole complex of laboratory research is needed. For examination of the patient, various specialists are involved. It is necessary to undergo an inspection of the gynecologist, a urologist and therapist. The need for examination from other medical professionals will indicate the attending physician. After collecting the results of laboratory tests, data of anamnesis, the identification of clinical manifestations is assigned to the use of certain drugs.

Cyclosporine is rarely used in the treatment of Ra, only in cases of refractoriness to other drugs. The dose is 2, 5- 4 mg / kg / day. The effect develops after 2-4 months. Side effects are serious: arterial hypertension, violation of the kidney function.

General symptoms:

Piogenous arthritis is unspecified. Infectious arthritis BDA

The degree of violation of the function

The new direction in the treatment of rheumatoid arthritis is therapy, providing for the use of so-called biological agents (BioLogic Agents). The effect of drugs is based on inhibition of synthesis of cytokines (TNF-α and IL-1β).

Dyspeptic phenomena skin itch, dizziness, leukopenia, damage to the retina.

Do not detect specific deviations

Arthrosis is a degenerative process in cartilage and bone tissue, occurring in disruption of metabolism, not associated with an inflammatory component. The main group of patients is the elderly people (by the age of 60 people diagnose dystrophic changes in the joints of the joints).

Types of arthritis

Minimization of side effects of therapy.

  • External examination of the child;
  • In this case, the following forms of juvenile arthritis are distinguished:
  • To begin treatment of reactive arthritis is necessary with the destruction of the infectious focus, that is, the pathogens of the original disease. To do this, you need to undergo a comprehensive examination of the entire body. After determining the causative agent, sensitivity to drugs are established. Bacterial infection is treated with antibiotics.
  • Azatioprine is used at a dose of 50-10 mg / day. The effect is developing after 2-3 months. Laboratory monitoring is required (OAK every 2 weeks, then every 1-3 months).
  • Fatigue, subfebilitation, lymphadenopathy, weight loss. 2.
  • Excluded: arthropathy during sarcoidosis (
  • It is reliably established that in 60% of patients with active rheumatoid articular syndrome, even with a third degree of illness, there is a decrease (or absence) of the progression of articular changes against the background of supporting remixide therapy. However, the use of this form of treatment is justified if the basic therapy did not give the expected effect.

Sulfanimide preparations (sulfasalazine, salazopyridazine) - 500 mg tablets

Instrumental research methods

Differential diagnosis

Arthritis is always inflammation, which over time, in the progression of the disease (with autoimmune nature), it applies to the entire body. That is why there are many concomitant signs with autoimmune arthritis - these are fever, and subfebrile temperature, and headache, and general ailment. With rheumatoid arthritis, the cardiovascular system is seriously suffering.

Treatment of juvenile chronic arthritis

Laboratory study;

Articular;

The use of antibacterial drugs is recommended on the initial, sharp stage of the alert. In the future, their use becomes less efficient. In some cases, symptomatic treatment is prescribed, in which drugs of a non-steroid group are used, for example, ibuprofen. "Anticycinic" RA therapy is based on the suppression of the main pro-inflammatory cytokines: TNF - A and IL - 1. Infliksimab registered in Russia is a monoclonal AT to FNF - a. Infliximab is used in a dose of 3 mg / kg to / in 2, 6, and then every 8 weeks. The effect of the effect - from several days to 4 months. Articular syndrome

The value of drugs of a number of NSAIDs, previously actively used in the treatment of the knee arthritis, was somewhat decreased, since other program of therapy appeared, characterized by higher efficiency. Infertility of the synthesis of prostaglandins and leukotrienes, inhibition of the synthesis of antibodies and the Russian Federation. Radiography, additional methods (MRI)
To diagnose "Arthritis of the knee joint" (Gonaritrite), it is necessary to conduct multidirectional diagnostic studies. In some cases, doctors are diagnosed with "Arthrosis arthritis of the knee joint With the system variant of juvenile rheumatoid arthritis, 40-50% of children are favorable forecast, it may occur to remission from several months to several years. However, the aggravation of the disease can develop years after the resistant. In 1/3 of patients, there is a continuously recurrent course of the disease. The most unfavorable prognosis in children with a stubborn fever, thrombocytosis, long-term therapy with corticosteroids. In 50% of patients, severe destructive arthritis develops, in 20% - in adulthood, amyloidosis is noted, 65% is heavy functional failure. X-ray study of affected joints.
Mixed (articular visceral); In order for the reactive arthritis, the chronic form is needed, a timely treatment is necessary. To make decisions on the reception of patients of those or other drugs should only attending a doctor. It is unacceptable to engage in self-medication. Combined therapy. The combinations of basic preparations are selected in order to potentiate the clinical effect without a significant increase in the risk of side effects. The combination of methotrexate, sulfasalazine and hydroxychlorochine is most well studied. They are recognized as successful combinations of methotrexate with lefluminumid, methotrexate with infliximab.
Symmetry - An important feature of the RA Morning stiffness is characterized by a symmetrical lesion of proximal interfalage, plump-stand-stand-standing, ray-tailed, toll-lineal joints, as well as other rheumatoid brush: ulnar deviation, deformation by the type "Boutonnieres" (flexion in proximal interfalage joints), "Swan neck "(re-exchange in proximal interphalating joints)," Hands with Lornnet "(with mutually *) Post-infection and reactive arthropathy ( Non-steroidal anti-inflammatory drugs ("Movied", Diclofenac - in tablets and in the form of injections) continue to assign in the diagnosis of arthritis, since these drugs have a pronounced anti-inflammatory effect and contribute to the overall improvement of the patient's condition.
Sernegative clinical and immunological option. Radiography, MRI. ​»​
All children with the early debut of the poliarticular seronegative youth arthritis have an unfavorable forecast. In adolescents with seropositive polyarthritis, high risk of heavy destructive arthritis, disabled on the state of the musculoskeletal system. An important meaning in diagnosis has clinical symptoms (the presence of rashes around the joint, stiffness, long-term course of arthritis, temperature lability, accompanying eye damage, lesion of lymphatic nodes). Medical examination of the child conducts a children's rheumatologist. Consultation of an ophthalmologist may be required. During a laboratory study, it is possible to reveal a decrease in the level of hemoglobin in the blood (anemia), the presence of rheumatoid factor, antinuclear antibodies. The rheumatoid factor is found in the blood not always. This is observed in the sernegative version of arthritis in children and adolescents. Form with limited viscerites.
An important point in preventive measures related to reactive arthritis is to prevent the infectious infection of bone tissue. To do this, you need to stick to the elementary rules of personal hygiene. Avoid embossing intestinal infections into the body, wash your arms before eating and after visiting the toilet, use individual dining devices. Pay attention to the need for the process of heat treatment of foods before use. Non-drug therapy. Arthritis
M03. Nevertheless, it has been reliably established that non-steroidal anti-inflammatory funds do not have a significant effect on the course of the disease of autoimmune nature - this is also evidenced by data of radiographs, and laboratory studies. However, the nonspecific process is well treatable by the drugs of the NSAID group. 500 mg / day with a gradual increase in dose to 2-3 g per day.
Treatment When the differential diagnosis between arthrosis and arthritis is usually at the initial stages of pathologies. In 40% of patients with oligoarthritis with early beginnings, a destructive symmetric polyarthritis is formed. In patients with late beginnings, a transformation of the disease in ankylosing spondylitis is possible. In 15% of patients with uveit, the development of blindness is possible.
A mandatory study method with suspicion of rheumatoid arthritis in children is a x-ray study or MRI. The main radiographic signs of the disease are the following: the narrowing of the articular slit of one or more joints, ankylosis, osteoporosis, the presence of bone erosions, a change in the cervical spine, the presence of uzurov, the destruction of cartilage. Uzura are boundary defects in the bone area. The progression of the disease can be slow, moderate and rapid. Stilla syndrome is a variety of arthritis arthritis. Oligoarthritis is two types. The first type is found very often. It accounts for about 40% of all cases of juvenile arthritis. Most often, this form of illness develops in girls, which are not 4 years old. It is important that not always during a laboratory study in patients with arthritis children in the blood detects a rheumatoid factor. We are talking about seronegative juvenile arthritis. From urinary infections will protect the use of a condom at sexual acts. The presence of a permanent partner in sexual life will reduce the risk of the disease. All of the above methods will contribute to the prevention of the ailment.
B. complex treatment Silent forms of RA, resistant to other types of treatment, are used by plasmapheresis and immunoadorption using protein A staphylococcus. ) Rheumatoid Stop: Fibular Deviation, Finger's Valgus deformation, soreness of the pink-standing joints of the rheumatoid knee joint: Baker cyst, bending and Valgus deformations The cervical spine: The subluxances of the Atlantosus joint Pensnaper-shaped joint: voices landslide, dysphagia. 3. ​. -*)​
Massage, LFC, Mud - All these methodologies are applicable only if the doctor rheumatologist found that inflammatory process Localized by medicine therapy, and the stage of remission has come. Special exercises and therapeutic massage are aimed at restoring the mobility of the knee joint. Stabilization of lysosomal membranes, braking phagocytosis and chemotaxis of neutrophils, inhibition of synthesis of cytokines. Complex (hospital + outpatient + sanatorium)
Table differential diagnosis Arthritis of the knee joint An increase in the level of C-reactive protein, IgA, IgM, IgG is a significant sign of an unfavorable forecast for the development of the destruction of joints and secondary amyloidosis. Depending on x-ray data, the stage of rheumatoid arthritis is determined. According to the classification, stage 1 is characterized by the presence of epiphyseal osteoporosis. At 2, osteoporosis is supplemented with a narrowing of the joint gap and single zoirs. For the 3 stages of the disease, the defeat of not only bone, but also cartilage tissue is characteristic. In addition, there are subsidiaries and multiple boundary defects. Arthritis 4 stages proceeds the most difficult. This stage is the destruction of cartilage and bone. Ankylosis develops. Conservative therapy At 4 stages of the disease ineffective. The most radical method of treatment is the conduct of surgical intervention.
Signs of Jura are diverse. The disease can leak acute or subacted. The sharp flow is more typical for children of preschool and younger school age. In the absence of therapy, the forecast is unfavorable. The main symptoms in this case will be: It is easier to prevent the disease than to treat it. In the event of the first signs of the disease, it is necessary to consult a doctor as soon as possible. Sinovectomy is rarely used due to the wide possibilities of active drug effects on synovit. Used prosthetics of hip and knee joints, surgical treatment of deformities of brushes and stop.
Defeating of near-chosen fabrics M01.0. When performing rotational motions, pain may occur, but this is a completely normal phenomenon, since the fabric during the progression of the disease has lost elasticity. All workouts and massage sessions must pass under the control of the doctor - this will help to avoid random injuries arising from excess of physical effort or loads.
Gold preparations (Tauredon) Comprehensive (hospital + outpatient + sanatorium Characteristic

Diagnostics of the knee joint arthritis

Mortality for youth arthritis is low. Most of deaths are associated with the development of amyloidosis or infectious complications in patients with a systemic version of juvenile rheumatoid arthritis, often arising from long-term glucocorticoid therapy. With secondary amyloidosis, the forecast is determined by the possibility and success of the treatment of the underlying disease.

Treatment is carried out only after diagnosis. It is required to exclude diseases such as ankylosing spondylitis, psoriatic arthritis, reactive arthritis, Reiter syndrome, systemic red lupus, tumor, behterev disease. In the presence of rheumatic diseases in children, treatment should be comprehensive.

Involvement in the joint process;

10th international Classification Diseases (ICD 10) Submits a variety of pathologies of joints and connective tissues under the codes M05 (seropositive), M06 (seronegative) and m08 (youth) rheumatoid arthritis. The rheumatoid polyarthritis is classified, which in the ICD is under the code M13.0, like other arthritis, depending on the presence of a rheumatoid factor in the blood.

Long outpatient surveillance.

Tendosinitis in the field of ray-tunny joint and brush bourssitis, especially in the area of \u200b\u200bthe elbow joint, the defeat of the ligament apparatus with the development of hypermobility and deformities lesion muscles: muscle atrophy, myopathy, more often medicinal (steroid, and also on the background of penicillamine reception or aminohinoline derivatives). 4.

* Meningococcal arthritis (

Balneological therapy is very effective procedures in a comprehensive program for the treatment of progress arthritis. However, this direction of rehabilitation is shown to those patients who do not have serious diseases Cardiovascular system, neoplasms of malignant nature, and also there were also no infarction or strokes. All procedures using therapeutic biological components are prescribed with great care.

Braking of the functional activity of macrophages and neutrophils, inhibition of immunoglobulin production and the Russian Federation.

Medicia treatment

Arthritis

Treatment

Due to the fact that the etiology of juvenile rheumatoid arthritis is unknown, the primary prophylaxis is not carried out.

Treatment of juvenile rheumatoid arthritis includes restriction of motor activity, preventing insolation, the use of NSAIDs in order to eliminate pain and inflammation, immunosuppressants, leaf, physiotherapy.

  • A slight increase in body temperature;
  • Under the polyarthritis, systemic multiple lesions of the joints are understood, in which not only almost all types of joints are inflated and destroyed, simultaneously or sequentially, but also other organ systems. Sometimes the result of a launched form of polyarthritis can be disability. Rheumatoid polyarthritis can act as an independent disease as an infectious-nonspecific rheumatoid polyarthritis, and sometimes it is the consequence of other diseases - sepsis, gout, rheumatism. There should be a fear of illness, even those who have sick teeth, but the word "dentistry" is unacceptable in Lexicon.
  • Observation is carried out together with a specialist - rheumatologist and precinct (family) doctor. The competence of the rheumatologist includes diagnosis, the choice of tactics of treatment, training the patient with the right regime, conducting intra-articular manipulations. Responsibility for organizing a systematic management of the patient carry general practitioners; They also carry out clinical monitoring. During each visit, the patient is assessed: the severity of pain in the joints on a 100-point scale, the duration of the morning stiffness in minutes, the duration of ailment, the number of sweat and painful joints, functional activity.
  • System manifestations
  • A39.8.

Since there are many varieties of arthritis and arthritic pathologies, it is necessary to contact the doctor when the first signs of the disease appears. The earlier the reasons that caused the inflammatory process will be determined, the more chances to cure the disease completely.

Mainly the articular form of RA, regardless of the activity of the disease. Antibiotics (purulent, reactive arthritis), NSPIDs, corticosteroids, cytostatics, vitamin preparations, blockades with GKS Arthrosis Arthritis is a disease of the joints of an inflammatory nature. According to statistics, every hundredth person in our country is sick arthritis. Symptomatic preparations (anesthetic from the NSAID and glucocorticoid group) are assigned during the aggravation of arthritis. "Indomethacin", "Diclofenak", "Nimesulid", "Naproxen" is most often used. From glucocorticoids - "Betamethasone" and "prednisolone". The group of basic drugs in the treatment of rheumatoid arthritis includes: "Methotrexate", "Sulfasalazine", "Cyclosporin", "Hydroxychlorookhin". Treatment with these drugs can last for years.
The appearance of rash on the body; Like any arthritis, polyarthritis occurs on the background of transferred infectious diseases (tonsillitis, viral hepatitis, Gonorrhea), joint injuries, allergic reactions and metabolism. Depending on this, several varieties of polyarthritis distinguish: exchange (crystalline), infectious, post-traumatic and rheumatoid (system). Until now, failed to accurately determine the causes of the disease, the result of which even disabilities can become. Sometimes the disease develops lightningry, that is, many groups of joints are affected at the same time, but in most cases the disease rheumatoid polyarthritis affects the joints gradually. Periodically (at least 1 p / year) is estimated: the dynamics of mobility, instability, deformation of the joints of the EEE and the RT-REDGRIOLOGIC Dynamics of bone densitometry (if possible). Rheumatoid nodules are dense subcutaneous formations, in typical cases localized in areas often exposed to trauma (for example, in the area of \u200b\u200bthe elbow process, on the extensible surface of the forearm). Very rarely discover in internal organs (for example, in lungs). Watch out 20- 50% of patients with skin on the skin of the shiny eye damage: sclert, episclerite; In the syndrome of the Schogrena - dry keratoconjunctivitis of heart damage: dry, less frequently, pericarditis, vasculitis, valvulitis, amyloidosis. Patients of RA are inclined to the early development of atherosclerosis Light lesion: interstitial light fibrosis, pleurisy, Kaplan syndrome (rheumatoids in lungs in mines), Light Vasculitis, oblique bronchioratic kidney defeat: Clinically weakly pronounced Mezangial or (less often) Membrane glomerulonephritis, amyloidosis of neuropathy: Compression (blind channel syndrome), sensory - motor neuropathy, multiple mononeurite (within the framework of rheumatoid vasculitis), cervical myelopathy (rarely) against the background of the Atlantoocciano Cystical Sustav of Vasculitis: Digital Arteritis with the Development of Hangle Finger in the body caused by violation of the functions of the reticulosendothelial system; Thrombocytopenia Schogren syndrome - autoimmune exocrinopathy, clinical manifestations: dry keratoconjunosis, xerostomy osteoporosis (more pronounced on the background of the treatment of GK) amyloidosis Syndrome Felti: symptom complex, including neutropenia, splenomegaly, systemic manifestations often leads to the development of non-good lymphoma Stilla syndrome Large criteria: fever 39 ° C and more for one or more weeks; Arthralgia 2 weeks and more; Maculoze or maculopapulous rash of color salmon, appearing during fever; Leukocytosis in the blood\u003e 10 109 / l, the number of granulocytes\u003e 80% Small criteria: pain in the throat, lymphadenopathy or splenomegaly; increasing serum transaminase levels that are not associated with the toxicity of drugs or allergies; Lack of the Russian Federation, the absence of antinuclear AT (Anat). ​+)​
In no way, do not attempt to draw up the therapy scheme yourself, especially take medicines. This is not only inefficient, but also dangerous. Medical techniques used in recent years in the treatment of arthritis of different etiology, have high performance, which is a weighty argument to use the methods of treatment offered by official medicine. Tauredon - 10, 20 mg / day, Symptomatic therapy, chondroprotectors, blockades with GKS Etiology The causes of the development of such a serious pathological process can be various factors, among which scientists consider genetic predisposition to be the main catalyst (this is primarily concerned with women).
These medicines are prescribed by a long course. With their help, it is possible to achieve long-term remission, improve the forecast for health, slow down the process of destruction of bone and cartilage tissue. These are drugs pathogenetic therapy. Treatment implies massage, diet observance and additional reception of vitamins. In the diet, it is necessary to include products containing vitamins and minerals (calcium, phosphorus). FDOs, phonophoresis, laser and therapy are used from physiotherapy methods. In the case of contractures, skeletal extract may be required. Lymphoenopathy; The very first symptom that cannot be ignored is the morning stiffness of the joints lasting for more than 20 minutes. Among other parameters characterizing the effect of treatment are, a general assessment of the activity is important, a total assessment of the patient's opinion, a functional status (standardized questionnaires).
Anemia, an increase in ESO, an increase in the content of the CRH correlated with the activity of the RA synovial liquid liquid, with low viscosity, leukocytosis above 6000 / μl, neutrophilosis (25-90%) of the Russian Federation (AT to IgG class IgG) is positive in 70- 90% of cases at The Schogren syndrome is detected by Anat, AT to RO / LA OAM (proteinuria in the framework of nephrotic syndrome due to the amyloidosis of the kidneys or glomerulonephritis of medicinal origin) an increase in creatinine, urea of \u200b\u200bblood serum (assessment of the renal function, the necessary stage of choosing and controlling treatment).
Treatment
Sources: Auranofin - 6 mg / day, supporting dose - 3 mg / day. LFK, Sanatorium, Physiotherapy, Massage Inflammation
The second factor is injuries associated with overpressure on the joints. In third place - supercooling. In addition, arthritis can develop as a complication after an angina, or viral infection. Especially often such a phenomenon is observed in childhood.
In the later stages of the disease in the development of ankylosis, endoprosthetics can be conducted (replacement of the joint on artificial). Thus, juvenile rheumatoid arthritis is an incurable disease and in the absence of pathogenetic therapy may result in disabilities. Increase in the size of the liver or spleen. Then your knees, elbows or brushes begin to respond to changing weather conditions, especially in the direction of their deterioration. Plowness, moderate morning pain and an increase in skin temperature on the area of \u200b\u200baffected joint mean that the specialized clinic is waiting for you immediately, because the success of rehabilitation depends on how early the disease was diagnosed. The frequency of laboratory monitoring depends on the nature of the LS used (see above). X-ray studies of the joints Early signs: osteoporosis, cystoid enlightenment of the okolosserty bone departments. The erosion of the articular surfaces used to be formed in the area of \u200b\u200bthe head-standard and powerful joints heads Late signs: the narrowing of the articular gaps, ankylose Regional features: the subluxances of the Atlanto Sustav, the protrusion of the head of the femoral bone in the godpadin.
Rheumatoid arthritis Rheumatology: National leadership ed. E.L. Nononova, V.A. Nonomic. Skin rash, stomatitis, peripheral swelling, proteinuria, myelosuppression. Showing during remission Degenerative changes in the joint
Arthritis affects all joints, but the most vulnerable is the hip area and knees, small joints of the brushes, less often - elbows, ankles. In the absence of treatment, articular deformation and immobility is inevitably developed. Juvenile rheumatoid arthritis (Yura) - arthritis of an unidentified cause, a duration of more than 6 weeks, developing in children under the age of 16 years old, with the exclusion of other pathology of the joints. In the acute course of the disease, two-sided lesions of the joints are observed. More susceptible to inflammation of the knee, elbow, hip joints. The sharp beginning is observed in the presence of a systemic and generalized type of arthritis. Any arthritis, including rheumatoid polyarthritis, will definitely lead to constant moving pain, especially at night, in the morning, sometimes there is an increase in body temperature. But the most pronounced factor is the joints and muscle atrophy around them. Rheumatic pain during periods of exacerbation is not amenable to treatment, and therefore the hospital expects a minimum of the patient at least twice a year. During this period, the appetite and body weight may decrease. Against the background of all changes, depression often arises, which only aggravates the state. The symptoms during the defeat of different joints may differ visually, but the full examination gives an accurate picture of the course of the disease. Criteria for the effectiveness of treatment.
Rheumatoid diagnosis criteria (RA) - inflammatory rheumatic disease of unknown etiology, characterized by symmetric chronic erosive Rheumatoid Arthritis E. N. Dormidontov, N. I. Korshunov, B. N. Frizen. D-penicillamine (capsules of 150 and 300 mg); Course (tablets 250 mg) Showing

Age group

The disease is not limited to age framework, but the middle-aged women make such a diagnosis more often than representatives of a strong half. The exceptions are infectious reactive arthritis, which are diagnosed mainly in men of 20-40 years (more than 85% of patients with reactive arthritis are NLA-B27-antigen carriers).

Depending on the type of classification, the disease has the following names: Youth arthritis (ICD-10), juvenile idiopathic arthritis (Ilar), juvenile chronic arthritis (EULAR), juvenile rheumatoid arthritis (ACR).

Often, the joints in the area of \u200b\u200bthe cervical spine are involved in the process. The articular syndrome is characterized by:

New techniques

This disease is difficult to treat. The only thing that patients may hope are long-term remission, when the hospital does not become the second home. In the early stages it is often possible to achieve, but in most cases the symptoms are renewed and even sharpened.

Evaluate and derive the degree of improvement (20%, 50%, 70%) using the indicators of the scores of the joint joints of the painful joints of at least 3 out of 5 indicators. General assessment of the patient's opinion. Total assessment of activity. According to the doctor's opinion assessment. (ESR, CRH) disability (estimated quantitatively using standardized questionnaires).

Arthritis

Arthritis

Arthritis and motor activity. Gordon N.F.

Rehabilitation programs

Suppression of collagen synthesis, inhibition of activity of T-helpers I type and in lymphocytes, destruction of the CEC

Arthritis of the knee joint can be diagnosed at home, if carefully examine the symptoms of the disease. Regardless of the etiology, such symptoms appear as swelling, redness in the joint area, overall malaise, external signs of deformation of the articular tissue.

Without restrictions (any age)

It is worth a details on rheumatoid arthritis (RA), which is autoimmune diseases with unclear etiology. The disease belongs to common pathologies - approximately 1% of the population suffers. Self-removal cases are very rarely found, 75% of patients have persistent remission; In 2% of patients, the disease leads to disability.

M08. Youth arthritis.

Stiffness in the morning duration up to 1 hour and more;

  1. The target of therapy with rheumatoid polyarthritis is to reduce rheumatic pains, reducing inflammatory processes, improving the mobility of the joints and preventing the complete immobility of the patient. The basic principles guided by any clinic, attending rheumatoid arthritis, is the complexity and systemicity. Well proved sanatorium-resort treatment through medicinal mud.
  2. Rehabilitation.
  3. American Rheumatology Association (1987)

SpinaZDorov.ru.

ICD 10. Class XIII (M00-M25) | Medical practice - Modern medicine diseases, their diagnosis, etiology, pathogenesis and methods of treating diseases

Peripheral joints and systemic inflammatory damage in the internal organs.

2 shoulder shoulder elbow joint bone

High Clinical and Laboratory Activity

However, the thought should not be asked how to treat the knee arthritis on his own, especially using the dubious recipes of folk healing. This can lead to irreversible consequences. The decision on how to treat arthritis of the knee is accepted only after a comprehensive examination.

As a rule, over 50-60 years

In this disease, the inner surface of the joints (cartilage, ligaments, bones) is destroyed and replaced by a scar cloth. The rate of development of rheumatoid arthritis is not the same - from several months to several years. Features of the clinical picture of a type of inflammation of the joints allow you to suspect the disease and assign the necessary surveys to confirm the diagnosis. In accordance with the ICD-10, classified RA seropositive (code M05), sernegative (code M06), youth (Code of MO8)

M08.0. Youth (juvenile) rheumatoid arthritis (gray-positive or seronegative).

Swelling in the joint area;

The first stage is the suppression of an autoimmune process, which actually leads to the destruction of tissues, pain, loss of ability to move. Next should be anti-inflammatory treatment, complete cleansing of the body from toxic exchange products. In the period of remission, blood circulation is reduced, improve the performance of the joints, normalize the metabolism. All of these stages are combined both by drug and physiotherapeutic treatment methods.

Infectious arthropathy (M00-M03)

An important role is played by the Flamm. Sanatorium - resort treatment is recommended during the minimum activity or remission. In order to correct deformations, orthoses apply - individual orthopedic devices from thermoplastic worn overnight. At least 4 of the following morning stiffness\u003e 1 hCode for the international classification of diseases of the ICD-10: 3 forearm, ray, ray-tailed joint, elbow boneInitial dose 250 mg / day with a gradual increase of up to 500-1000 mg / day; Supporting dose - 150-250 mg / day

M00 Piogenic Arthritis

Doctors must determine the nature of the disease to prescribe adequate treatment. The direction of laboratory and instrumental studies give orthopedic traumatologists, surgeons, rheumatologists. The therapy scheme is developing a profile specialist (it can be a phthisiar, a dermatologist-venereologist, cardiologist and other doctors). The nature of the process Some types of arthritis are striking only children and adolescents, so they should be allocated in a separate row.M08.1. Youth (juvenile) ankidozing spondylitis. Soreness;The basis treatment is suppressing an autoimmune process by means of such drugs: methotrexate, sulfasalazine and leflomide. In terms of information to a minimum of side effects is distinguished by the latter, it should be considered from that position that they all require a long (at least six months) of use. Features of pregnant womenArthritis M06 -4 Brush wrist, joints between these fingers, bones, stain Skin rash, dyspepsia, cholestatic hepatitis, myelosuppressionThe first stage for determining the disease (according to the ICD 10) is a visual inspection, the collection of anamnesis. Acute or chronicJuvenile rheumatoid arthritis (according to the ICD-10 code M08) affects children after transferred bacterial and viral infections. It is inflamed, as a rule, one knee or other major joint. The child has pain in any movements, in the field of swelling. Children are seeded, with difficulty get up in the morning. In the absence of treatment, the deformation of the joints is gradually developing, which is no longer possible.

M08.2. Youth (juvenile) arthritis with system start. Changing gait;Non-steroidal anti-inflammatory drugs (NSAIDs) also have an anesthetic effect. But they should also be used for a long time, so the doctor must choose the one that is best tolerated patients. Diclofenac, ibuprofen, nimesulide are widely used among nesteroids. All of them are striking the gastrointestinal tract to a greater or lesser extent. Pregnancy improves the course of RA, however, after the delivery, there is always a recurrence due to hyperprolactinemia. NSAIDs in the I trimester of pregnancy and 2 weeks before delivery to apply undesirable (in I trimester - the risk of teratogenic effect, before childbirth - the threat of developing the weakness of generic activity, bleeding, early closure arterial flow in the fetus). Gold salts, immunosuppressants pregnant people are contraindicated. There are data on the relative safety of the use of aminohinoline preparations and sulfasalazine, nevertheless the expected effect should be correlated with a possible risk. 3 joints and more

Other rheumatoid arthritis5 Plumber Beds Bed joint, region and thigh Area, sacchant-iliac, femoral joint, bone, pelvis Methotrexate (Tablets of 2.5 mg, ampoules of 5 mg)The second stage is laboratory testing of blood (with inflammation there is an increase in ESR, leukocytosis, a marker of inflammation of CRH, other specific reactions).

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Arthritis rheumatoid, disease and treatment by folk and drugs. Description, Application and Healing Properties of Herbs, Alternative Medicine

  • Always chronic

Arthritis Rheumatoid: Quick description

Reactive children's arthritis (according to the ICD-10 code MO2) manifests itself two weeks after transferred intestinal infection. If the process develops in a knee joint, then external signs are well noticeable: the skin is blushing, a swelling is visible without pronounced borders. The child often rises the temperature that decreases from the antipyretic drugs, but the soreness in the knee area is preserved. M08.3. Youth (juvenile) polyarthritis (seronegative). Violation of the functions of the affected body.It happens that non-steroidal drugs are not able to facilitate the suffering of the patient, so the clinic decides on the use of glucocorticosteroid (GKS) drugs - hormones that can be administered directly to the affected joint. GCS have a mass of side effects, but they are prescribed by brief courses, which significantly reduces the risk.

The factors of an unfavorable forecast of RA include: Seropozitivity in the Russian Federation in the debut of the disease Female Paul. Young age At the time of the beginning of the disease System manifestations High ESP, significant concentrations of CRPs HLA is the HLA - DR4 Early appearance and rapid progression of erosions in the joints. Low social status of patients.

  • Arthritis Operating classification of rheumatoid

6 skin is a mulberry knee joint, bone, tibia antagonist of folic acid; Suppresses the proliferation of T- and B-lymphocytes, the products of antibodies and pathogenic immune complexes. The third stage is x-ray. In the presence of arthritis, the curvature of the articular surface, bone ankylosis is revealed.The beginning of the disease In addition to infectious, reactive, rheumatoid arthritis, children are often diagnosed with allergic nature. The child's illness begins suddenly - immediately after entering allergens into the blood. The joints quickly swell, shortness of breath appears, urticaria. Can develop swelling of quinque, bronchial spasm. When eliminating allergic reaction Arthritis signs. M08.4. Phasiarticular youth (juvenile) arthritis. If juvenile arthritis affects the minor joints of the fingers or legs, then the deformation of the fingers is possible. In the arthritis arthritis, the defeat of the organs of vision is often observed. Iridocyclite develops or takes. At the same time, visual acuity may decrease. The serongative form of arthritis proceeds more easily compared to seropositive. In the latter case, rheumatoid nodules are often detected in the joints of the joints. Modern medicine, attending rheumatoid polyarthritis, uses new biological preparations, overwhelming protein activity. These are drugs such as Etnersept (Enbrel), infliximab (remikad) and adalimumab (Humir). Their side effects are significantly less, and the result they give positive. ArthritisSymmetric brushes joints Arthritis7 Ankle Plusn, ankle joint, the joint and stop is replous, other foot joints, foot fingers RA with systemic manifestations, high activity of RA, low efficiency of other basis products.The fourth stage is MRI, an ultrasound (prescribed for the differentiation of arthritis from arthrosis, diseases of Bekhtereva and Bursita). With erased signs that are in the sluggish chronic process, additional hardware studies of the joint can be assigned - tomography of articular tissue, CT, pneumatic architecture. Acute, suddenThe arthritis of the knee joint can develop as an independent disease, so be a complication after injuries and diseases. M08.8. Other juvenile arthritis.With the pathology under consideration, other important bodies suffer often. With system form, arthritis may occur:

Statistical data

With serious complications, more radical treatments are used - hemosorption and plasmorosis, in which blood is subjected to complete cleaning and re-introduced the patient. The use of enterosorbents is considered to be the use of enterosorbents when the useful substances remain in the body, and only toxins are exposed to the elimination.

Arthritis Rheumatoid: Causes

Etiology

Infectious non-specific

Genetic features

Arthritis

Pathogenesis

(1980) in form:

Arthritis Rheumatoid: Symptoms, Symptoms

Clinical picture

8 Other heads, neck, ribs, skull, torso, spine 7.5-25 mg per week orally.At the same stage, the joint puncture and the capture of the synovial fluid for a laboratory study (if testimony is biopsy). Gradual (develops months, years)The knee joint, struck by arthritis, swells, with its movement, pain appears. The skin in the joint area changes the color (blushing or becomes "parchment"), but this is not a reliable sign of the inflammatory process. M08.9. Youth arthritis is unspecified.Exanthema; People's methods cannot be the only way to treat when it comes to a polyarthritis. It is better to apply them during the remission, as more gentle by side effects. With visible inflammatory processes, chamomile baths have proven well. Arthritis rheumatoid nodules of the Russian Federation X-ray changes The first four criteria must exist at least for 6 weeks. Sensitivity - 91, 2%, specificity - 89, 3%. Rheumatoid

Arthritis rheumatoid: diagnosis

Laboratory data

9 Localization of uncomfortable

Tool data

Mielosuppression, liver damage (fibrosis), lungs (infiltrates, fibrosis), activation of chronic infection foci.

When determining the type and degree of reactive arthritis (Code of the ICD-10), biological material (general blood and urine tests) is investigated, a urogenital and ophthalmic study is carried out, a test for the presence of HLA-B27, an ECG, thymol sample, a sialic sample, determination of Alt, is prescribed. AST, sowing biological fluids. SymptomsThe main reason for the appearance of swelling and visually noticeable increase in the knee cup is the accumulation of fluid inside the joint. Excessive pressure on the walls of the joint tissue causes severe pain. The volume of fluid over time is steadily increases, therefore it becomes more intense pain syndrome.Juvenile rheumatoid arthritis is one of the most frequent and most disabilities of rheumatic diseases, which is found in children. The incidence of juvenile rheumatoid arthritis is from 2 to 16 people per 100,000 children's population under the age of 16. The prevalence of juvenile rheumatoid arthritis in different countries is from 0.05 to 0.6%. More often, rheumatoid arthritis is sick. Mortality is 0.5-1%. Defeat kidney in the type of glomerulonephritis;Orally take infusions from birch kidney, tricolor violet, nettle, hernial. The collection of herbs, which includes a row, chamomile, a series, lingonberry, juniper (berries). This fee is half a cup of three times a day before the meal is very effective in the exchange polyarthritis. Progressive deforming, infectrite, polyarthritis infectious non-specific, polyarthritis primary chronic, polyarthritis, rheumatoid, polyarthritis chronic polyarthritis. Since the highest growth rate of radiographic changes is observed Early stages of RA, active therapy (NSAIDs in an adequate dose + base drugs) should be started during the first 3 months after the diagnosis of reliable ra. This is especially important in patients who have the risk factors of an unfavorable forecast, which include high Titres of the Russian Federation, a pronounced increase in ESP, defeat more than 20 joints, the presence of embracing manifestations (rheumatoid nodules, firing syndrome, episclerite and scarce, interstitial lung damage, pericarditis, systemic vasculitis , Feeltic syndrome). The use of GC is shown in patients who are not "responding" to NSAIDs or having contraindications to their purpose in an adequate dose, as well as a temporary measure before the effect of basic means. Casting Introduction GK is intended for the treatment of synovitis in 1 or several joints, which complements, but does not replace the complex treatment. ArthritisViolations affecting mainly peripheral joints (limbs)

Arthritis Rheumatoid: treatment methods

Treatment

Total tactic

Azatioprin, Imuran (Tablets of 50 mg)

Mode

Treatment of reactive arthritis, in accordance with the ICD-10, is carried out in two directions - these are therapy using antibacterial agents and elimination of articular syndrome (pain, stiffness).

As a rule, sharply expressed

In addition, under the joint, uric acid crystals are deposited, which have the type of thin ridicule spikes. They injure small vessels, which is the basis for the development of attached infections. Teenagers have a very unfavorable situation on rheumatoid arthritis, its prevalence is 116.4 per 100,000 (in children under 14 years old - 45.8 per 100,000), primary The incidence is 28.3 per 100,000 (in children under 14 years old - 12.6 per 100,000).

Pericarditis;During the remission, pepper trings with kerosene are used. Such procedures not only remove pain and inflammation, but also penetrate the blood, partially cleaning it. As in the conditions of the hospital, and at home you can apply treatment with cold. In the hospital, cryosaurs are used - special cabins with cooled air, which are replaced by ice in bags at home. After the procedure, the duration of about 10 minutes the joints massage and knead. For one cooling procedure produced three times. The duration of treatment is 20 days.

The ICB-10 patients should be formed by the stereotype of movements, opposing the development of deformations (for example, to prevent ulnar deviation should be opened a crane, typing a telephone number and other manipulations are not right, but with left hand).: Polyarthritis, oligoarthritis, monoarthritis rheumatoid NoteInhibition of proliferative activity of T- and B-lymphocytes.

Despite the leading role of x-ray in the diagnosis of arthritis, it is necessary to remember that pathological changes in the pictures are not always visible in the early stages of the disease. Arthrography is an informative value for doctors in the study of large joints, and during polyarthritis this diagnostic method is not effective. Serological reactions are used to identify the causative agent of arthritis of infectious nature.

Manifest as changes in cartilage and bone tissue

Arthritis of the knee proceeds hard not only because of the intensive pain syndrome, but also in connection with the violation of the activities of functional systems. Especially strongly suffer from cardiovascular and endocrine systems. There is a shortness of breath, tachycardia, subfebilitation, sweating, circulatory disorder in limbs, insomnia and other nonspecific signs.

Three classifications of the disease are used: classification of juvenile rheumatoid arthritis of the American Board of Rheumatologists (ACR), classification of juvenile chronic arthritis of the European League against rheumatism (Eular), classification of juvenile idiopathic arthritis of the International League of Rheumatology Associations (Ilar).

Inflammation of the heart muscle;

Special attention is paid to the diet. Healers recommend raw materials, especially widespread use in eggplant food. In any case, the rheumatoid polyarthritis can be curbed, without giving him to spoil the quality of life of the patient.

M05 Seropositive rheumatoidoid

Drug treatment

Arthritis

RA with system manifestations.

The treatment of arthritis is a long-term process and requiring not only the implementation of the doctor's recommendations for drug therapy, but also the passage of rehabilitation courses. Intensity of pain

Surgery

Symptoms differ depending on the degree of violation of the function, stage and etiology of the disease:

Classification of juvenile chronic arthritisPleurisy;

Any arthritis, supplied in the ICD 10 under codes M05, M06, M08, M13.0, requires constant attention, since even a long-term remission does not help avoid spontaneous exacerbation of the disease.

Arthritis

Non-steroidal anti-inflammatory means

With systemic manifestations Special syndromes: Fegelty syndrome, stylted syndrome in adultsThis group covers arthropathy caused by microbio logical agents

150 mg / day, dose of maintenance - 50 mg / day.Diet in the arthritis of the knee joint should be observed strictly. The food is excluded, rich in carbohydrates, smoked, oily meat, legumes. When translating diet nutrition And the use of individual therapy is a positive effect. In general, the treatment of the arthritis of the knee joint provides for the following directions:

Strongly expressed from the very beginning of the disease

The first degree is characterized by moderate pain syndrome, there is a slight limited movement with the rotations of the knee, when climbing or during squats.

Forecast

For the first time, juvenile rheumatoid arthritis was described at the end of the last century by two famous pediatricians: an Englishman style and french Chaffar. Over the next decades in the literature, this disease was named as a disease of Stilla Shaffara.

Synonyms

Loading liver and spleen.B. pediatric practice Juvenile rheumatoid arthritis occurs often. This pathology proceeds similarly to adult arthritis. The disease is characteristic of children under 16. This is the most frequently diagnosed disease in rheumatology. Girls suffer from arthritis 1.5-2 times more often. The disease is completely impossible to heal it. Treatment is also carried out throughout life. It is important that in the absence of due therapy, juvenile arthritis may cause early disability. What is the etiology, clinic and treatment of the disease? M06 Other rheumatoid arthritisNon-selective inhibitors of cyclooxygenase (COW) "Gold Standard" remains diclofenac 50 mg 2- 3 R / day Prolonged drugs Diclofenac 100 mg / day retain the relevance of derivatives of arylpropionic acid as having the lowest percentage of gastrointestinal complications: ibuprofen 0, 8 g 3- 4 p / day naproxen 500-750 mg 2 p / day ketoprofen 50 mg 2-3 p / day (possesses high analgesic activity) indoletaceous acid derivatives Indomethacin 25- 50 mg 3 R / day prolonged indomethacin preparations 75 mg 1- 2 p / Der derivatives of enolics acids Pyroxikov 10-20 mg 2 p / day Selective COF inhibitors - 2 meloxico 7, 5-15 mg / day nimesulide 0, 1-0, 2 g 2 p / day Cextoxib 0, 1 g 2 p / day.

Abbreviation

Surprised​ ​Mielosuppression, activation of chronic infection foci.Drug funds (tablets, injections, ointments, gels);

First expressed moderately, gradually growing

Rheumatism on the ICD 10 is an autoimmune disease associated with the emergence of circulating immune complexes after contacting the body with a hemolytic streptococcus group A. Developed with congenital similarities of the antigenic structure of connective tissue and streptococcus, the valve apparatus of the heart, large joints and CNS affect. It is divided into the forms of the disease with the formation of heart defects and without that.

This pathology may occur after the suffered angina. In modern times, rheumatism is much less common, the massive use of antibiotics does not allow to develop autoimmune processes.

The occurrence of the disease in developed countries among the adult population is up to 0.9%, and at child age - at least 0.6%. With the development of rheumatism from the young age to mature age (30-40), it does not live about 80-90%.

Rheumatism on the registry of the ICD 10 is a systemic autoimmune disease. Its classification is based on the defeat of the joints, heart valves, central nervous system, stages and degrees of severity of the disease.

For a complete list of this pathology, the International Classification of Diseases of the 10th Revision is used. On the ICD - 10 each disease has its own encoding. The rheumatism code begins to the Latin letter I under which all diseases of the circulatory system are meant. The code cipher of rheumatism and rheumatic fever is under numbers 00 - 09.

Acute rheumatic fever (Eagle - rheumatism code for ICD 10 I00-I02).

I 00 rheumatic fever without influence on heart disease.

I 01 Rheumatic fever with influence on the appearance of heart disease.

I01.0 pericarditis;

I01.1 endocarditis;

I01.2 myocarditis;

I01.8 Other sharp rheumatic heart disease.

I 02 Khorora.

Chronic heart rheumatic diseases (I05-I09 code):

I 05 Rheumatic diseases of the mitral valve.

I05.0 Mitral stenosis;

I05.1 Mitral insufficiency;

I05.2 Mitral stenosis with mitral insufficiency.

I 06 Rheumatic diseases of the aortic valves.

I 07 Rheumatic diseases of the trilateral valve.

I 08 Multiple valve lesions.

I 09 Other rheumatic heart lesions.

I09.0 rheumatic myocarditis;

I09.1 Chronic endocarditis, Walvulit;

I09.2 Chronic pericarditis.

Classification of rheumatism

Clinicians and theorists allocate two forms of rheumatism - active and inactive. Some divide the progressive, fading and recurrent phases. This pathology can be in a chronic stage with the involvement of the valve apparatus and myocardium. Palindromic (repeated) rheumatism was described back in 1891

In medicine, there is a classification of rheumatism on two criteria: according to clinical manifestations and degree of activity of the disease.

Clinical manifestations of acute rheumatic fever:

1. Signs of the disease
Maintenance Non-core (extra)
carditis (inflammatory diseases of the 3rd shells of the heart); fever (inflammatory connective tissue disease);
attitis (inflammatory lesions of the joints); arthralgia (soreness in the joints);
chorea (disorderly motion syndrome); sumoros (inflammation of serous shells: pleura, peritoneum, in the heart - pericardia)
Rheumatic nodules (dense formation, localized under the skin, is characterized by inflammation of the connective tissue in the shells of the heart). Abdominal syndrome (acute belly, is a list of certain symptoms characterizing the peritonean irritation).
2. Eagle current activity:
1 degree - minimum (inactive);
2 degree - moderate;
3 degree - high;
3. The consequences of acute rheumatic fever:
· No heart defects;
· With heart defects;
· Complete recovery.

Classification of rheumatism according to the degree of activity:

First degree. The minimum degree that has low-rise symptoms. Differs insignificant symptoms or their absence.

Second degree or average degree in activity. It can pass together with fever and cardit. It is characterized by an increase in ESP, leukocytes and a number of other blood test indicators.

Third degree (maximum). It is characterized by the advent of fever with the flow of liquid in the cavity (polyarthritis, serozite). The biochemical analysis has sharply increased the content of proteins - inflammation (CRH, A-globulines, sermochoid) and enzymes.

Due to the diagnosis, the CNS, heart, joints and other organs occurs. Often, professors characterize the illness of the expression "rheumatism kisses the brain, licks the joints and bits the heart."

Such a disease is quite difficult to treat, however, with a proper and timely examination, a complete recovery comes treatment.

Causes and risk factors

The main reason for the occurrence of such a disease is the infection of the group A bacterium, only beta hemolytic streptococcus contains a rheumatogenic factor that determines the development of rheumatism. The second reason is considered the similarity of the microbial antigens and cartilage tissue. In the aggregate, these reasons can cause the development of an autoagression of the immune system against the connective tissue of the body.

RICK RICK RICK FACTORS:

  • the presence of a characteristic streptococcus causeing hemolysis (provoking factor);
  • genetic predisposition of immune status;
  • inflammatory factors.

The course and forecast of the disease

Rheumatism flows in 3 stages:

  1. An autoimmune (it occurs in it the appearance of immune compounds antigen antibody and the production of autoantibodies).
  2. Vascular (pathology from the microcirculatory line and the coagulating blood system, leading to the formation of thrombus).
  3. Inflammatory (exudative connecting tissue reactions).

Eagle and rheumatism:

In 75% of patients with attacks of rheumatism, no more than 6 weeks are sick, in 95% of patients for 12 weeks complete recovery comes. And only 5% the course of the disease can exceed six months. For such patients, all clinical manifestations are characterized in severe and running form. The frequency of exacerbations depends on the degree of re-infection of the bacterium, the presence of damage to the cardiovascular system and the duration of the remission.

Cardness develops from almost all patients. In the absence of rough noise over the top of the heart, you should judge a favorable forecast of rheumatism.

Rheumatoid arthritis - chronic illnessAt which the synovial membrane is inflamed, which is why the joints lose mobility and swell. Gradually, the inflammation destroys the ends of the bone and the coating articular surfaces of the cartilage. The structure and functions of bundles that give joint strength and it begins to deform.

Most often, the disease amazes a few joints and usually begins on one of the small - brushes or feet. As a rule, the disease develops symmetrically. The eyes, lungs, heart and blood vessels can be involved in the inflammatory process. The disease is usually developing slowly, but clinically manifests dramatically.

Rheumatoid arthritis is an autoimmune disease, i.e. The synovial membrane, and in some cases other parts of the body damage their own antibodies.

At-risk groups

Women over 60 years old are more often sick, men are 3 times less. The disease can be hereditary. The way of life does not matter.

General symptoms

  • weakness;
  • pallitude of the skin;
  • shortness of breath at any voltage;
  • bad appetite.

General symptoms are partially due, and it occurs because it decreases the amount of bone marrow, in which blood cells are formed.

Characteristics

  • sustaines lose mobility, hurt and swell;
  • in areas experiencing pressure (for example on elbows), characteristic nodules appear.

Since the disease simultaneously brings pain and deprives mobility, patients often begins. In women suffering from rheumatoid arthritis, the condition can improve during pregnancy, but after the birth of a child, the attacks are renewed.

With the course of the disease due to low mobility, the density of bones connecting in the joint are reduced, they become fragile and easily break. In severe cases, osteoporosis of the entire skeleton is developing.

In addition, it may develop, i.e. Inflammation of the articular bag. The swaths of wrist tissue squeeze the middle nerve, which is why numbness, tingling and pain in the fingers of the brush arise. If the walls of the arteries that supply fingers supplying blood are inflated, it develops, in which, especially in the cold, the fingers begin to root. Less often increases the spleen and lymph nodes. Cardiac bag can be inflated - pericardium. In some cases, eye proteins are inflated.

For rheumatoid arthritis it is characteristic that the attacks with a length of several weeks to several months are replaced by relatively asymptomatic periods. Similar, but with characteristic features, arthritis form is observed in children (see juvenile rheumatoid arthritis).

Diagnostics

It is usually based on the history and results of the general examination of the patient. To confirm the presence of antibodies (so-called rheumatoid factor) and establish the severity of inflammation, conduct blood tests. The destruction of bones and cartilage is assessed by X-ray shimmers of affected joints.

Health care

Rheumatoid arthritis is incurable. The task of the doctor is to take the symptoms of the disease under control and not give the disease to progress so that the joints do not destroy further. There are many drugs whose choice depends on the severity and stage of the development of the disease, the age of the patient and the overall state of his health.

If there are easy symptoms, will be assigned. However, at the beginning of the disease, the doctor may write more strong drugs that change its flow. They must limit the irreversible destruction of the joints, but they will have to take several months before the improvement comes. First assign or. If the symptoms do not pass, the compounds of gold are prescribed, or. New drugs aimed against tumor necrosis factor can also be applied. Since all these drugs are characterized by severe side effects, the patient must be under constant supervision.

With anemia, which often accompanies rheumatoid arthritis, erythropoietin hormone is prescribed to improve the condition, which increases the formation of red blood cells.

To reduce the burden on a particularly painful joint and prevent deformation, most likely, it will be recommended to wear longs or corsets. To strengthen the muscles and not lose the mobility of the joints, we will suit gentle, but regular exercise. For this, they also conduct physiotherapy and / or work therapy. To remove pain, prescribe hydrotherapy, as well as hot or cold heels. With very strong pain, the doctor can make corticosteroid intra-articular injection. If the joint is destroyed very much, spend a surgical implantation, replacing it with a prosthesis.

Precautions

Most people with rheumatoid arthritis are able to lead a normal lifestyle, but in order to eliminate the symptoms, a lifelong reception is required. Approximately 1 of the 10 patients due to constant attacks of the disease develops severe disabilities. In order to track the development of the disease and the reaction to treatment, you need to regularly donate blood for analysis. Sometimes the attacks are gradually weakened, and the disease is exhausted, but in these cases there may be some irreversible changes.