Mikoses of the skin is a modern state of the problem. Diagnosis and treatment of micaosis of the skin and nails. Clinical manifestations of Mikosa Stop and Nail

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Skin myoses are fungal diseases that cause infectious microorganisms. They hit the skin and subcutaneous tissue, penetrating through scratches and microtraums. Then the disputes of fungi fall through the mucous membrane in airways And accumulate in lungs. The stage of the disease depends on the focus of infection and a particular fungus. The development of this illness can provoke any disease that weakens the body's immune system.

From the place of damage to the microbes apply to other skin sites and infect the mucous membrane, genitals, digestive systemLight. The face, hair, torso, arms, legs and even nails suffer from illness.

The danger of the ailment is that he often has chronic form. The earlier contact medical institution For help with mycosis, the faster the treatment will pass and recovery will soon come. This ailment is able to disfigure the skin of the face, hands, legs and other parts of the body, hit any organs and cause concomitant diseases (allergies, Mikids). The risk group of Mikosa is children and people of old age, although the person of any gender and age can pick up the infection.

Varieties of mikosa skin

Mycosis is a large group of diseases. Various subspecies of pathology differ in localization and degree of lesion. There are two main groups. Deep myoses are opportunistic and subcutaneous, sporerchosis, chromoblastomycosis. Surface - candidiasis, dermatomycosis and keratomicosis.

  • keratomicosis. From this group, it is most often found, for which characteristic is the appearance of spots on the body, a person who, as the pathological process progressing, begin to peel;
  • dermatomicosis. This group combines several types of skin diseases. The appearance of dermatomycosis is spoken if characteristic red spots appear on the body, skin surfaces are inflated, their active peeling occur;
  • candidiasis - These are diseases caused by yeast fungi. The ailments of this type are distributed through the tissues of all organs and parts of the body, with the exception of hair. The infection is most often developing in skin folds. The most dangerous places - in the axillary depression, in interdigital spaces;
  • histoplasmosis, chromomicosis, cryptococcosis, etc. This group infectious diseases It is characterized by infection of deep layers of the skin, and therefore they are the most dangerous and hard, but they are quite rare. In this case, it is necessary to diagnose in a timely manner and carefully and assign adequate treatment. As a rule, it is very difficult to treat these pathology.

Mycosis of leather is acute and chronic, deep and superficial, focal and distributed.

The reasons

The main reason for all skin micoses is a fungus that develops and affects the tissues of organs and parts of the body. The danger of the disease is that all patients are sick in different ways. Some are infected immediately, other disease occurs hidden, and thirdly the presence of infection in the body does not cause the development of pathology and they become carriers of fungal dispute.

The mechanism of development of the disease depends on the protective factors of the body of a particular person. If a person has weak immunity or, takes antibiotics or has skin damage, badly observes hygiene, the risk of developing this fungal disease is very high. You can still add trophic ulcers to this. Best fungus breeds and grows in a wet and warm environment.

Infectious microorganisms are capable of penetrating inside during medical procedures. When the body's protective forces are reduced, conditions for invasive growth of fungi appear.

Since myoses of the skin of the face, hands, legs and other parts of the body are developing in a weakened organism, this infection may be progressing during or immunodeficiency if there is a malignant neoplasm or after the transmission of antibiotics, steroids.

If the infection is insignificant, the micaosis may not be accompanied by numerous symptoms. But systemic myoses widely spread and affect any body sections: from the scalp and face skin to nail tips. The system can be attributed to the candemic and visceral candidiasis, meningitis of infants, streptococcal pneumonia and disseminated candidiasis, aspergillosis of the brain, lungs and middle ear.

A variety of mushrooms that cause microwiek skin, affect people and animals. They fall into the body in various ways. The main paths are microcracks and significant damage to the skin, medical manipulations. Factors contributing to their further development in the human body, chronic diseases and various violations of the body's processes.

So, the most frequent reasons Infection with fungal disputes:

  • weakened immune system;
  • chronic ailments;
  • bad hygiene;
  • prolonged adoption of drugs;
  • poor food and reception of low-quality products;
  • bad habits;
  • spoiled medicines, etc.

Symptomatics

With mycosis, the skin is various symptoms, but they do not appear immediately. Symptoms largely depends on which portion of the body was affected by this infectious disease. If itching and peeling the skin on face, hands, abdomen, back, legs are the first symptoms of mycosis. The patient should immediately refer to a qualified technician for diagnosis and treatment. This stage of illness is very good to treat with anti-grab drugs and, as a rule, does not cause complications.

The micaosis of the smooth skin of the follicular-nodular shape is characterized by a pustulatory rash. Infection can hit even flush hair. Quite often appear diameters between the fingers. This is how the micaosis of the skin of the arms and legs begins. As the pathology progresses, holoptysh arise, and the skin of the legs are arisen. In addition to peeling, such symptoms can appear as painful purulent bubbles, the nails begin to get lazy, yellow and can be significantly collapsed.

The micaosis of the head of the head is manifested not only by peeling, but also dullness, weakening hair. Particularly unpleasant face skin face. In general, the patient can increase body temperature, arise painfulness and general weakness.

The problem is that the primary symptoms are so insignificant that the person himself does not pay attention to them and does not appeal to the doctor. At this time, the disease gradually progresses and then harder to heal. If the disease is detected on early stage, That is, more chances to cure mycosis completely without the likelihood of recurrence. But without competent and timely treatment Deals can give a large number of complications.

Diagnosis and treatment

Diagnose such a disease can dermatologists or physicians micols. First of all, you need to come to a consultation to the doctor. He must inspect the foci on the skin of the face, limbs and other parts of the body, take superficial scales for a laboratory study under a microscope. To designate proper treatmentIt is necessary to determine the cause of the disease with the help of culture research methods.

As for the treatment itself, there is no one-time method, since it must be comprehensive and directed not only to recovery, but also to eliminate the causes that caused illness. Therefore, the course of treatment is developed depending on such factors:

  • duration of the disease;
  • type of infectious fungus;
  • location of the hearth;
  • the spread of infection;
  • the state of the body as a whole;
  • opportunity allergic reaction on any drugs;
  • the age and features of the patient's body.

Therapeutic therapy picks up a narrow specialized physician (dermatologist or mycologist). Drug addicts accumulate in blood and help restore skin cover. Most often doctors prescribe "Grieseofulvin". It is safe and practically does not give side Effects. Therefore, it is most often prescribed for the treatment of children. The following drugs are equally effective:

  • "Ketoconazole";
  • "Iratenazole";
  • "Fluconazole";
  • "Terbaphyl".

To decide on the drug, first need to set the kind of fungus. Then the doctor prescribes the most effective medicine.

More doctors can assign a wide range of action. All of them must have an anti-grapple effect. To not be side effects, the patient needs to be constantly under the control of the doctor. During pregnancy and lactation, women are proceeding with anti-grab medications. It should be very careful to pick up treatment to patients who have liver disease or allergies.

Besides medicines, It is necessary to use ointments, sprays and creams with anti-grab components in the treatment: "Ekonazol", "Mikonazole", "oxyconazole". Useful substances penetrate the focus of the reproduction of infectious bacteria and kill them. Mazi is also selected taking into account the individual characteristics of the patient. Sometimes you need a focus of infection to stick with adhesive plaster. If the infection has spread to flush hair, they need to be removed by removal by removal.

After passing the full course of treatment, you need to pass tests for the presence of fungus. This will help the doctor to determine whether the patient from Mikosa is completely cured. If there is a negative result, it means that the treatment has passed successfully. In the case, if the result is positive - the doctor needs to develop a new treatment plan, more efficient. Since skin myoses may appear again, prophylaxis should be carried out.

Treatment with folk remedies

If a person has symptoms of the skin of the skin, first of all, you need to go to the hospital for consultation to the doctor who will conduct diagnostics and prescribe a course of treatment. But the funds of traditional medicine will help substantially alleviate. They do not guarantee complete recovery, but only will be auxiliary option. All procedures must be performed overnight.

The affected area is well washed with running water. After that, it needs to be treated with a cotton swab with iodine or green. Also damaged areas of the skin can be treated with herbs - white or teasel, grated black or lomonos. You can still apply ointment based on swine fat, vaseline and herbs. But picking up dryweights, be sure to consult with the doctor.

Immunomodulatory properties have plants such as Veronica, licorice, cleanliness, ore. also in folk medicine Mustard, mint, yarrow, hops, dandelion and joster are widely used. The antifungal properties possesses cleanly, a non-lunist, tess. The use of folk remedies will help eliminate unpleasant symptoms of illness. But it is possible to apply them for treatment only with the permission of your attending physician.

Prevention

There is a possibility of recurrence of the skin of the skin. If the person appeared the first symptoms pointing to mycosis, that is, redness and itching, it is immediately necessary to visit the medical institution. In order not to infect with the spores of the fungus, prophylactic actions should be carried out, the main thing is to improve the observance of hygiene. When visiting the sauna, the pool, the general shower must be worn out shoes. After that, it is recommended to process shoes by salicylic alcohol. It is also worth remembering that in a healthy body, fungal infection cannot be rooted, so it is necessary to strengthen its immune system everyday.

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Term "Micose skin" Doctors designate an extensive group of infectious diseases characterized by damage to the skin of fungi. Major skin in most people begins with a slight discomfort - the skin of the toes or hands is slightly covered and itches.

The fungus may affect almost any part of the body: if the areas are not affected on which the hair grows, the disease is called the micaosis of smooth skin if the head of the head is amazed, this is a mycosis of hazel skin.

The treatment of mikosa smooth skin depends on the type of fungus, the area of \u200b\u200bthe affected area and the stage of the disease.

People who are far from medicine or never faced with similar problems know what MIKOS is, for its domestic name - deprive.

Lishe is a common variety of Mikosa, often transmitted from pets, often children suffer from this disease.

Mycosis is caused by fungi. Almost all of them are pathogenic for human organism (Abnormal and provoke diseases), with the exception of fungi of the genus Candida. They are conditional pathogenic - this means that in certain quantities, fungi form part normal microfloraBut with excessive reproduction is danger.

Candidosis microorganisms begin to spread in the body if it is weakened by the long-term intake of antibiotics, treatment of immunity diseases, poor ecological situation and unfavorable radiation background.

In addition to the fungi of the genus Candida, common pathogens of the disease are also microorganisms Trichophyton and Microsporum. They cause lesions of the epidermis and top layer of the skin.

Malassezia Furfur mushrooms provoke multicolored deprived. In total biologists, approximately 500 kinds of fungi causing skin disease were revealed.

Types and types of Mikosa


At the location of the localization of infection, doctors classly classify mycoses into the following types:

  1. mikoz torso;
  2. mycosis Stop;
  3. mICKOV Hand Skin;
  4. mikoz nail;
  5. mycosis smooth skin scalp;
  6. mycosis of the scalp (the latter is rare enough).

Allocate also different kinds Mikosov, depending on the type of microorganisms provoked by the disease:

  • dermatomicosis (or dermatophytium). They are called Trichophyton, Epidermophyton and Microsporum mushrooms. Strike predominantly nails, feet, hands, scalp;
  • keratomicosis. The pathogen is yeast-like Malassezia Furfur fungi. The horny layer of the skin and the epidermis are vulnerable, as well as hair follicles. Keratomicosis are both well-known seborrheic dermatitis and multicolored deprived. Mushrooms are well multiplied in a wet and warm environment, distributed in the warm season and in countries with the appropriate climate;
  • candidomykosis. Call candida mushrooms. Dangerous in that they are able to hit not only the skin, but also the mucous membranes of the body ( oral cavity, genitals, intestines), then spread to internal organs;
  • deep myoses - A variety of illness, striking not only the skin, but also internal organs. He is the hardest form, requires a long systematic treatment;
  • pseudomykosis - diseases that are very similar in symptoms similar to mycoses, but are caused by not fungi, but by bacteria, respectively, require other treatment. Determine the pathogen and the diagnosis will help the laboratory test, which is carried out when contacting the dermatologist.

Symptoms


The disease, as a rule, makes itself felt by turning the skin, itching, small bubbles localized in the same area. So begins to manifest mycosis of the skin. For such "minor" symptoms, most people do not pay attention, and in vain: at this stage, the fungus is easily excreted from the body, but very few people are drawn to the doctor with primary manifestations of skin problems.

Anxiety, as a rule, is already evidenced by the explicit manifestation of the disease: strong redness, exfoliation of the top layer of the skin, pain and itching of the affected area (these are signs of mikoz smooth skin).

The appearance of diaper disposals, rash, irritation in the groin area, cavities between fingers and legs, on elbow bends, under the breasts in women should also be a reason to melted and suspect the micaograph of the folds.

Nails sign about infection by uneven color change, fragility and peeling plate. If amazed maspress part Heads, foci are manifested in the form of one or more irritated areas from which hair falls out.

The affected area usually has a circle or oval form, framed by a red roller. Bubbles jump on the redneck part of the skin.

The reason to immediately consult a doctor is the appearance of several local lesions on the body, which can grow and merge into a single inflamed area. In this case, almost certainly the skin suffers from fungal infection and needs systematic treatment.

Methods of transmission


"Do not try to iron a wandering cat - deprive you," hears a formidable warning from parents every child, caring for animals. And well, if the elders are listening: the microwieth of the skin easily indulgesed a person from infected animals, the carriers of the disease can be cats, dogs, small rodents, cows, pigs.

If you keep your pet and your baby's baby in your favorite, it is recommended to strictly follow the observance by the child of simple hygiene rules: after games with a cat or a dog, you need to wash your hands thoroughly.

Animal must be periodically examined - a pet Can bring infection from the street or from their fellow. Well, if the animal made all the necessary vaccinations and you regularly show it to the veterinarian: not only mycoses can be passed through dogs and cats, but the mass of other diseases can be transmitted.

The microwieth of the skin is easily transmitted with direct contact with the sick person of using the general item items. If in your family with someone such a trouble happened, in no case do not use the general objects of life with sick - dishes, towels, clothing, bedding. Otherwise, it will be treated with the whole family.

Mikosis, causing mushrooms, sufficiently survivo in the external environment. Especially favorable conditions for them are created in public baths, saunas, pools, shower. In a warm and wet environment, the mushrooms are well multiplied, so when visiting such institutions it is desirable to bring their own hygiene objects - soap, towels, sheets, slates.

Footwear after the bath and the pool need to rinse very thoroughly and dry, if possible, treat salicylic alcohol. The office also desirable to have their own soap and towel.

Infection fungi is also possible during medical procedures and manipulations. The council here is the same: if you appealed to the health care institution, do not hesitate to clarify whether all the necessary hygiene rules are respected by doctors and nurses. And, of course, do not neglect them when they are treated at home.

The danger of sick with mycosis increases, if a person has been treated for antibiotics for a long time, he has weak immunity or chronic diseases. The fungi is easily penetrated into the body, if the skin is broken: infection occurs through cracks, abrasions and scratches on the skin.

The main function of our skin is barrier, protective. That is why injuries and wounds are recommended to disinfect as soon as possible and not allow dirt. Microorganisms otherwise can get immediately into the bloodstream, and not to localize on external covers.

To protect yourself from the damage to fungi, doctors are recommended to closely monitor the condition of the skin, dry out after the bath or soul (mycosis of the skin develops in the cavities of the fingers and hands), immediately contact the specialists at the first signs of violations of normal skin.

Treatment


On the Internet you can find a description of the set folk methodsthan treat skin diseases. Apply them is desirable only after consulting a doctor. Mycosis of leather is the most different, treatment has many features and is selected individually for each patient.

First of all, the doctor must send a patient to study the sample of affected skin in the laboratory. This is necessary to identify a specific causative agent. The choice of physician physician will also be affected by factors such as the depth and area of \u200b\u200bthe affected area, the location of the disease localization, the degree of its development, general state Health and Immunity, Availability chronic diseases, Patient age, the possibility of an allergic reaction to drugs.

If you appealed to the doctor at an early stage of the development of the disease, outdoor use antifungal masses Allows you to defeat the micaosis of smooth skin. And local treatment, and the intake of drugs will be required in the case when the disease struck the extensive area of \u200b\u200bthe skin.

To treat mycosis will be prescribed primarily by antifungal drugs used by local: it is ketoconazole, clotrimazole, fluconazole, terbinafil. They are applied to the affected areas twice a day.

On the advice of the doctor at night you can process the skin salicylic Masowingand in the morning - iodine solution. The micaosis may affect the fellows on the hips, the legs, forearms. In this case, besides local therapy, it is necessary to remove the epilation of patients.

Take inside the patient mycosis, most likely, prescribe Griseofulvin. The drug is safe, it has proven itself well, it is prescribed even to children. However, Griezoofulvin is able to accumulate in the liver, so be sure to warn your attending physician if you have problems with this body.

The effectiveness of selected drugs will be noticeable almost immediately, inflammation and peeling will pass, the skin will acquire its normal shade, they will grow healthy nail plates. If the improvements do not occur, again we go to the doctor and understand the reasons - perhaps a stronger medicine is required.

After successful therapy and disappearance external signs Mikosa The doctor must necessarily direct you to a re-laboratory study to make sure that there is no fungus in the body.

Prevention of Mikosa

In order not to let the infection in your own body, you need to stick to several simple rules:

  1. strictly observe hygiene, take into the public swimming pool, bath, sauna own towels, sheets, sneakers, carefully watched after the soul. It is advisable not to wear close shoes and prevent sweating of the legs;
  2. disinfect wounds and skin damage;
  3. strengthen the immunity, follow the condition of the skin and turn to the doctor in time when it changes.

A. Yu. Sergeev, Candidate of Medical Sciences,

O. L. Ivanov, Doctor of Medical Sciences, Professor

Fungal infections of skin, hair and nails are attributed to the group of surface micaoses. At the same time, skin lesions can be observed at subcutaneous, and at deep mycoses, which is much less common. About half of 400, with excess causative agents of mycoses cause skin infections.

According to the largest epidemiological studies of Achilles, held in 1997-1998 and covered 11 European countries, including Russia, mycoses of smooth skin are about 2%, and mycoses of stop and onychomycosis (mycoses of nails) - 22% of the reasons for the doctor's appeal. About a third of patients of dermatologists come to the reception about mycoses of the stop, and almost half appeals about onichomicoses.

Modern classifications allocate various surface micoses depending on the localization of the lesion or from the type (group) of the pathogen.

Mycoses Stop

Mycoses Stop (Tinea Pedis) are common everywhere and occur more often than any other skin micoses. According to different data, they suffer to 1/5 of the total population. The main causative agent of Mikosa Stop is T. Rubrum, much less often mycosis stops T. mentagrophytes var.interDigitale, even less often - other dermatophytes. Mycoses Stop, due to T. Rubrum and T. Mentagrophytes, have features of epidemiology and clinical picture. At the same time, options for Mikosa Stop typical for one pathogen, but caused by others are possible.

Infection by mycosis Stop caused by T. RUBRUM (RUBROFITING STOP), it takes more often in the family, with direct contact with the patient, as well as through shoes, clothing, or general items. Infection is different chronic flow, damage to both stops, frequent propagation on smooth skin and nail plates. With prolonged flow, it is characterized by the involvement of the skin of the palms, as a rule, the right (working) brush is the "two stop and one brush" syndrome (Tinea Pedum et Manuum). Usually T. RUBRUM causes a chronic squamous-hyperkeratotic form of a footboard, the so-called "moccasic type". With this form, the sole surface of the foot is affected. In the affected area there is a light erythema, moderate or pronounced peeling, and in some cases - and a thick layer of hyperkeratose. Hyperkeratosis is most pronounced at the points carrying the greatest load. In cases where the focus is solid and covers the entire surface of the sole, the stop becomes as if dressed in a layer of erythema and hyperkeratose like moccasins. The disease is usually not accompanied by subjective sensations. Sometimes the manifestations of Rubrofithius stop are minimal, represented by a slight peeling and cracks on the sole - the so-called erased form.

Infection by mycosis Stop due to T. Mentagrophytes (Stop epidermofitilation), occurs in public areas - sports halls, baths, saunas, pools. In the epidermofitilation stop, the interfalic form of Tinea Pedis is usually observed. In the 3rd, 4th, sometimes in the 1st interpalistic fold, a crack appears, along the edges of the frozen white strips of maceraged epidermis, against the background of the surrounding erythema. These phenomena may be accompanied by unpleasant odor (especially when the secondary joining bacterial infection) And, as a rule, painful. In some cases, the surrounding skin and nails of the nearest fingers of the foot (I and V) are affected. T. Mentagrophytes is a strong sensitizer and sometimes causes the vesiculous form of the Mikosa Stop. In this case, fine bubbles are formed on the fingers, in interpallated folds, on the arch and side surfaces of the foot. In rare cases, they merge, forming bubbles (bullous form).

In the treatment of Mikosa, stops are used both local and systemic antifungal agents. Local therapy is most effective with the erased and interpal forms of the Mikosa Stop. Modern antimicotics for local application include creams (for example, lamisyl, exoderyl, lowland), aerosols (lamisyl, daktarine), ointments (for example, various drugs Clotrimazole). If these tools are not available, local antiseptics (Castellanic liquid, Fuccin, etc.) are used. The duration of treatment is from two weeks when used modern drugs up to four - when using traditional means. With chronic squamous-hyperkeratotic form of the Mikosa Stop, the involvement of brushes or smooth skin, the lesion of the nails local therapy is often doomed to failure. In these cases, systemic drugs are prescribed - terbinafin (lamisyl, exifun) - 250 mg per day for at least two weeks, itraconazole (neungal) - 200 mg twice a day for one week. With the defeat of the nails, the therapy time is extended. Systemic therapy is also shown in isgery, vesiculous bullous forms of infection. Outwardly, in these cases, the binds, solutions of antiseptics, aerosols, as well as combined means combining corticosteroid hormones and antimicotics (Triederm, Lorinden C, Candid B, Myxolon). Desensitizing therapy is shown.

Onychomicoses

Onychomicoses are affecting about 1/10 of the entire population and are common everywhere. The incidence is rising with age (up to 30% after 65 years), which is primarily due to the pathology of vessels, obesity, osteoarthropathies of the foot, as well as diabetes. The main provoking factor is damage to the nails and the skin of the foot, most often when wearing close shoes. Onychomicoses in the footsteps are found three to seven times more often than on the brushes. The main causative agent of onychomicosis - T. RUBRUM. However, up to 1/4 of the nail infections can be caused by mold and yeast mushrooms, resistant to a number of antifungal agents.

There are three main clinical forms of onychomicosis: distally lateral, proximal and superficial, depending on the place of deployment of the pathogen. Most often occurs a distal form. At the same time, the elements of the fungus penetrate into the nail from the affected skin in the disturbance area of \u200b\u200bthe distal (free) end of the nail and leather. The infection applies to the root of the nail, and for its promotion, the superiority of the growth rate of the fungus is needed over the speed of the natural growth of the nail in the opposite direction. The growth of the nail slows down with age (up to 50% after 65-70 years), and therefore onichomicoses and prevail in the elderly. Clinical manifestations of the distal form - the loss of the transparency of the nail plate (onicholysis), manifested as whitish or yellow spots In the thicker of the nail and the subband hyperkeratosis, in which the nail looks thickened. With a rare proximal form, the mushrooms penetrate through the proximal nail roller. White or yellow spots appear in the thicker of the nail at its root. With surface form, onychomycosis is represented on the surface of the nail plate. Each of the forms of onchomicosis with time can lead to the defeat of all nail departments, the destruction of the nail plate and the loss of the nail function. Similar variants of onychomicosis refer to the so-called total dystrophic form.

Candidiasis of nails is usually accompanied by paronymia - inflammation of the olock roller. As a result of periodic exacerbations of paronymichs, dystrophic nail changes occur, manifested by transverse furrows on the nail plate.

The main means of confirmation of the diagnosis is microscopy of pathological material (fragments of the nail plate and dismissal material from under it) and its sowing with the release of culture. The latter is not always possible and not always available to all domestic laboratories.

The treatment of onychomicoses also use local and systemic therapy or their combination - combined therapy. Local therapy is applicable mainly only under surface form, initial phenomena of distal shape or losses of single nails. In other cases, systemic therapy is more effective. Modern local means For the treatment of onychomicosis include antifungal nail polishes, in particular, the preparation of lawscel with a convenient application scheme (once a week). Local therapy is conducted before clinical and micrical cure. Systemic therapy includes terbinefin preparations (lamisyl, exifun in tablets), itraconazole (neongal in capsules) and fluconazole (diphalcan in capsules). Terbinefin preparations are effective in onchomicosis caused by T. Rubrum and T. Mentagrophytes dermatophys, Diflucan - dermatophytes and Candida yeast mushrooms, and onchomicosis of any etiology. Lamizil or exifun is prescribed 250 mg per day for 6 weeks and more in the onchomicosis of the brushes and from 12 weeks - during the onchomicosis of the stop. The neungal is prescribed in 200 mg pulse-therapy mode twice a day for one week with a three-week interval, and then repeat this cycle once with the onchomicosis of the brushes and at least two times during the onchomicosis of the stop. The duration of treatment with any drug depends on clinical form Onychomicosis, prevalence of lesion, degree of subnumber hyperkeratosis, affected nail and age of the patient. To calculate the duration, a special Kyotos index is currently used [Sergeev A. Yu., 1999]. Combined therapy can be assigned in cases where only systemic therapy is not enough or it has a greater duration. The effective and convenient scheme of combination therapy is the combination of the drug Diflucan (150 mg once a week) with simultaneous or subsequent purpose of the lacquer Loceryl, also once a week, to clinical cure.

Mycoses Smooth skin and large folds

Mycoses smooth skin (Tinea Corporis s. Circinata) are less common than mycoses stop or onchomicosis. As a rule, in Russia they are caused by T. Rubrum (ferrochetium smooth skin) or Microsporum Canis (smooth skin microsporography). Zoonous mygoses are also found, caused by raree types of dermatophytes. Mikoses of large folds (Tinea Cruis) are usually called T. Rubrum and Epidermophyton Floccosum, there are also clidiasis of large folds.

The foci of mikoz smooth skin has characteristic features - ring-shaped eccentric growth and festened outlines. Due to the fact that in infected skin, the phases of the introduction of the fungus in new sections, an inflammatory response and its permission are gradually replaced, the growth of foci from the center to the periphery looks like an expanding ring. The ring is formed by the erythema and infiltration roller, in the center it is marked with peeling. When merging several ring-shaped foci, one big hearth is formed with polycyclic diplomatic outlines. For rubrofythius, as a rule, the striking adults are characterized by common foci with moderate erythema phenomena, while the patient can also detect the mixture of stop or brushes, onichomicosis. For a microsporry, as a rule, the striking children in mapping from pets are characterized by small coin aluminum foci on closed areas of the skin, often the centers of the scalp microsist microspory.

In some cases, doctors, without recognizing the micaosis of smooth skin, are prescribed to the center of erythema and infiltration corticosteroid ointments. At the same time, inflammatory phenomena are subsided, and mycosis takes an erased form (the so-called Tinea Incognito).

Mikoses of large folds caused by dermatophytes (Tinea Cruir) also retain characteristics: peripheral roller, permission in the center and polycyclic outline. The most typical localization is the inguinal folds and the inner side of the thigh.

For the candidiasis in this localization, cracks, erosion and sections of macerated skin are characterized in the depth of folds, merging erosion, papules and pustulas, which are the focus of the lesion, and similar elements-checkouts along the edges of the hearth. All rashes in the groin area are usually accompanied by itching.

In the treatment of mycoses, smooth skin and folds use the same principles as in the treatment of copies of the stop. Local antifungal agents are prescribed on insulated foci, with common foci, systemic drugs are prescribed according to similar schemes, and when a combination of nail or hair lesions, system therapy is prescribed according to the schemes adopted for these localizations. Treatment with local drugs is conducted before clinical and micrical cure, after which another week is added.

Multicolored lichen

Multicolored (degree) Lishe causes Mushroom PityRosporum Orbiculare (Sin. Malassezia Furfur). The disease is common in hot countries, and in our climate is striking up to 5-10% of the population. Multicolored deprived develops more often in persons with high sweating, characterized by exacerbations in the hot season.

Elements of multi-colored linga are located on the skin of the chest, the top of the back, shoulders. In this area, small spots first appear pink, and then yellow or coffee, light brown. Against the background of tanned skin, the stains look lighter. Spots are prone to merge with the formation of large foci, but can exist isolated. There are no inflammatory phenomena, there is a slight seven-party peeling.

In the diagnosis of multi-colored damage is used by iodine Balsera Sample: Spots are lubricated with the iodine tincture, after which they acquire a dark brown color. Under the Wood lamp, the foci of multicolored deprived give yellow glow.

Multicolored treatment is usually carried out by local antimicotics: creams (nipped, lamisyl), aerosols (lamisyl, daktarine). These funds are used twice a day for two weeks. A comfortable form is the antifungal shampoo nipped. It is used once a day for 5-7 days. With common lesions and frequent relapses of multi-colored delay, systemic antimitics are prescribed: naked or neungal 200 mg per day for one week.

Literature

1. Rodionov A. N. Fungal diseases Skin. St. Petersburg: Peter, 1998.

2. Mitavishnikova V. M. Myzes Stop. M.: MSD, 1999.

3. Sergeyev Yu. V., Sergeev A. Yu. Onychomikozes: Fungal infections of nails. M.: Gootar-Medicine, 1998.

4. Sergeev A. Yu., Sergeev Yu. V. Candidiasis: the nature of infection, mechanisms of aggression and protection, diagnosis and treatment. M.: Triada-X, 2000.

5. Stepanova J. V. Fungal diseases. M.: Kron-Press, 1996.

Mycosis smooth leather - dermatrophia, in which reddish stains with flaming edges are formed on cover. With absence medical treatment In places of lesion, scales appear, which are covered with papulas and pustulas without a central pressure.

Modern specialists share such a micaosis on the dermatomycosis and keratomicosis. It should be noted that the nail plates and hair can also suffer from them.

The reasons

Provoke the development of mikosa smooth skin can a huge number of factors. It should be noted that, according to statistics, every second person on Earth faced with such a disease.

Call similar mycoses can:

It should be noted that the micaosis of smooth skin can only develop with a weakened immunite. If a person has everything in order with protective functions, pathogenic microorganisms will not be able to develop. They will show themselves with distinctive signs only with the decrease in immunity. For this reason, you must regulate regularly vitamin complexes and follow the rules healthy image Life.

Symptoms and forms

Recognize such damage to the skin, the symptoms of which appear only with long-term development, quite simple. A person gradually begins to face a number of problems that complicate his life. Recognize mycosis of the skin is possible by:

  1. peeling cover;
  2. the emergence of red inflamed spots;
  3. inflammation and swelling;
  4. formation of papural;
  5. the emergence of diaper disposals;
  6. constant toide and burning.

With the appearance of any signs of such a disease, you should immediately visit the attending physician. Only he can identify defeat and appoint the most appropriate treatment. You should not ignore the defeat, since otherwise you risk allowing the development of serious complications. Also, a specialist will be able to identify what type you have a micaosis smooth skin:

Medicia treatment

It is very important that the treatment of microwave smooth skin passed under the complete control of the doctor. For therapy, it is necessary to use antifungal drugs, without which it will not be possible to get rid of the causative agent. They are needed for both local and general therapy. It should be noted that the doctor should engage in the selection of medicines - only he will be able to assess the degree of damage, as well as the individual characteristics of the body. Usually, the terbinefin cream, miconazole and others are used for therapy. They are applied to the skin 2 times a day.

Terbinafin Ketoconazole Clotrimazole Mikonazole

It is also necessary to regularly process the affected areas with sulfur tincture, salicylic acid or. This will help create a sour Wednesday that mushrooms do not tolerate. It is also impossible to do without taking tablets that kill pathogens inside the body. In no case do not appoint them yourself - this can lead to sad consequences. For the treatment of mikosa smooth skin on the hips or legs, it is necessary to stick the damaged areas with the plaster and remove hair with the help of epilation.

Sulna tincture Salicylic acid iodine

A dairy and salicyl collodia can be perfectly able to cope with such a disease that must be used 4-5 times a day. You can also make compresses from salicyl or zinc Mazi.who perfectly remove inflammation. Over time, you can notice how all the signs of illness go, and the skin, hair and nails begin to recover. You will have to do to make sure that the treatment is correct.

Treatment with folk remedies

On the initial stage Mikosa smooth skin can be treated folk remedies. However, you need to adhere to all precautions and take into account that with a long lack of effect from the selected therapy, it is necessary to immediately consult a doctor.

Even ordinary coffee will help to cope with such damage - you just need to brew this drink and breed it in the bathroom. It must be taken every day for 2 weeks. Over time, you will notice how the skin becomes smooth and silky, and inflammation and swelling begin to leave. Also for similar therapy apply the following recipes.

Chapter 1. Review of literature.

1.1. Epidemiology of the incidence of fungal lesions of the skin.

1.2. Etiopathogenesis.

1.3 Clinical picture and diagnostics.

1.4 Treatment and prevention of fungal skin diseases.

Chapter 2. Volume and methods of research.

2.1. Justification of the required scope of research.

2.2. Justification of the application of clinical research methods.

Own research and discussion.

Chapter 3. Results of the survey of patients with fungi

Diseases in the Republic of Tatarstan.

Chapter 4. Comparative Results Feature

Treatment in the studied groups.

4.1. Characteristics of methods for the treatment of patients in the studied groups

4.2. Assessment of the dynamics of major clinical manifestations and laboratory indicators in the treatment process.

4.3. Dynamics of quality of life in patients in studied groups.

Recommended list of dissertations

  • Mycoses of the skin and its appendages in patients receiving systemic glucocorticosteroids 2006, Candidate of Biological Sciences Gudkov, Julia Igorevna

  • Features of the clinic and treatment of dermatomykosis in veterans of special risk units 2008, Candidate of Medical Sciences Vashkevich, Arina Aleksandrovna

  • New approaches to the complex therapy of Mycoses Stop 0 year, Candidate of Medical Sciences Petrasyuk, Oksana Aleksandrovna

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The dissertation (part of the author's abstract) on the topic "Myzo Stop: rationalization of therapy"

The relevance of the problem

Surface mycoses are one of the most common diseases in the practice of dermatologists. - In the structure of the skin pathology, the incidence of fungal lesions of the skin continues to occupy a leading position: according to different data, the share of mycoses ranges from 37 to 42% of all diseases of the skin and nails. One of the ways to reduce the incidence of Mikosami Stop is the need to study the epidemiological conditions specific for each region, the degree of urbanization, working conditions, clinical features In order to improve the effectiveness of the fight against Mikosami Stop [Shorty N.G., 2001]. According to the Ministry of Health of the Republic of Tatarstan, the incidence of Mikosami in RT for 2006 amounted to 152.2 per 100 thousand population. Although in 2007 its decrease was noted by 9.6%, yet it, in general, remains high.

In most cases, mycoses stop are the main sources of propagation of fungal infection among the population, a kind of "transshipment point" to spread the pathological process to the nails, the foot, skin and nails of the brushes [Stepanova Zh.V., Novoselov A.Yu., Vorobiev I.V. , 2005].

Mycoses Stop have a negative impact on the quality of life and the general health of the patients, amazing the most able-bodied population, and make this problem not only medical, but also socio-economic. According to various authors, the ICC clinic is currently underway certain changes - there is a tendency to the rapid chronic and prevalence of the process [Pearls Yu.N., Olkhovskaya NB, 2006].

Currently, somatically burdened patients often meet at the same time several skin disease. In such patients, with a long existing mycosis, another dermatosis occurs. Most often to mix diseases should be attributed to the eclae, psoriasis, skin angiites, grinding inflammation.

After the emergence and implementation of systemic practice antifungal drugs Many dermatologists have doubts about the feasibility of conducting local antifungal therapy in some categories of patients. However, after a while it became clear that not all patients were able to use systemic antifungal drugs due to the high risk of unwanted phenomena and possible medicinal interactions. In addition, with limited lesions of the skin, there was no need to prescribe systemic antimicotics [Lykov S.G., Nemchaninova OB, Petrenko O.S., Borovitskaya ON, 2005].

At first glance, the treatment of limited skin micoses does not represent difficulties with the diversity of modern aptyphounding drugs for external use. However, in some cases, antimicotics for outdoor use not only do not have the necessary effect, but also contribute to exacerbation. inflammatory processwhich is manifested by the strengthening of itching, hyperemia, exudation and the appearance of vesiculation and mocking. As a rule, this is due to two reasons. First, the pathogens of the skin of the skin are lowly sensitive to the appointed antimicotics. Secondly, if the micultural process proceeds sharply with pronounced exudation, then the appointment of even an effective antifungal can lead to an increase in the manifestations of the inflammatory process. In such cases, anti-inflammatory activity of the antifungal drug for local treatment is not enough [Vassenova V.Yu., 2008; Vasiliev N.V. et al., 2007].

From here there is a practical need for persistent searches and aporbations medicinal preparationspossessing wide spectrum biological activity.

Based on the foregoing, the purpose and objectives of the study were identified.

Purpose of the study

Study of epidemiology, modern etiological and clinical aspects of the flow of fungal feet in the region of the Republic of Tatarstan and assessing the effectiveness of the new treatment method.

Objectives of research

1. To explore the current state of morbidity and the frequency of occurrence of causative agents of Mycoses of Stop in the Republic of Tatarstan.

2. Analyze clinical manifestations Mycoses of Stop in the Republic of Tatarstan with the definition of specific gravity and the structure of their complicated forms.

3. Assess the clinical efficacy of natural terpeneoids (the drug "Abisil", registration No. 003339/02 dated November 24, 2003) in the treatment of complicated forms of mycoses of the stop.

4. Examine the dynamics of indicators of cellular and humoral immunity in patients with complicated shapes of mycoses stop in the process complex therapy.

5. Evaluate the hepatotoxicity and nephrotoxicity of the proposed new treatment technique.

Scientific novelty

The current state of the incidence of fungal infection was studied, the species composition of the causative agents of the copies of the Stop in the Republic of Tatarstan, the proportion and structure of their complicated forms were determined.

The changes in the immune status of patients with Mikosami Stop depending on the presence of fungal associations are studied.

The possibility of increasing the adhesion of the S. albicans mushroom adhesion as part of fungal associations isolated from feet patients with mososets.

For the first time, a method of therapy of complicated forms of copies of the STOP with the use of the drug "AbiSil" has been developed, its effectiveness and safety has been proven.

Practical significance

Based on the conducted study, the prevalence was established, the leading pathogens of fungal diseases of the skin, the proportion and structure of complicated forms of mycoses of the STOP in the territory of the Republic of Tatarstan, which seems important for practical health care is determined.

Conducting the active detection and clipco-laboratory screening of mycoses of stop and onychomicosis included an increase in the awareness of the primary health care physicians.

Developed and tested method comprehensive treatment Complicated forms of copies of the STOP using the drug "ABISILE", which increases the effectiveness of treatment and has a minimal panel effect.

Based on the results of the study, the monograph "Myzes of Stop in the Republic of Tatarstan" was prepared and published.

The main provisions of the dissertation submitted to defense

1. In the Republic of Tatarstan, there is a high morbidity incidence, which determines a third of the entire dermatological morbidity (27.8%). In the etiological structure of this pathology, the leading place is occupied by dermatomycetes (65.7%), mainly mushrooms of the genus Trichophyton: Trichophyton Rubrum (48.1%) and TRICHOPHYTON MENTAGROPHYTES VAR. Interdigitale (13.8%), detected both separately and in the form of fungal associations with yeast-like and / or mold mushrooms. Mycoses Stop in the overall structure of fungal morbidity are 75.3%).

2. Among mycoses stopped complicated forms determine 14.8%, representing a serious medical problem in the Republic of Tatarstan.

3. The use of the drug "AbiSil" in complex therapy of complicated forms of mycosis stops efficiency and reduces patient treatment.

Implementation into practice

The results of the study and the basic guidelines are implemented and used in the practical work of the Naberezhnoglinsky Skin-Venereological Dispensary (QW) and Chistopol KVD, as well as in the educational process of the Department of Dermatovenerology of the Kazan State Medical University and Kazan State medical Academy.

Approbation of work

The main provisions and fragments of the dissertation work are reported and discussed on: meetings of the Tatarstan branch of the Russian Scientific Society of Dermatovenerologists (2006, 2007, 2008), a regional scientific-practical conference "Synthesis and prospects for the use of new biologically active compounds" (2007), interdisciplinary A scientific and practical conference dedicated to the 135th anniversary of the Department of Dermatovenerology of the Kazan State Medical University: " Modern methods diagnosis and treatment of skin diseases and sexually transmitted infections (2008). The dissertation was tested at the Inter-Federal Meeting Department of Dermatovenerology of the Kazan State Medical University and Kazan State Medical Academy, the Laboratory of the Mikology of the Kazan Research Institute of Epidemiology and Microbiology of Rospotrebnadzor of the Russian Federation, Republican Clinical Skin-Venereological Dispensary.

Publication of research materials

Thesis and structure of the dissertation

The thesis is preserved on 119 pages of the typewritten text and consists of an introduction, a review of literature, two heads of their own research, discussion of the results obtained, practical recommendations, conclusions, a literature of references containing 85 domestic and 66 foreign sources. Illustrative material is represented by 20 tables, 15 drawings.

Similar dissertation works in the specialty "skin and venereal diseases", 14.00.11 CIFRA VAK

  • Features of the clinic and the flow of combined leather lesions stop 2012, Candidate of Medical Sciences Savenko, Ekaterina Leonidovna

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  • Improving the laboratory diagnosis of onychomicosis based on the method of polymerase chain reaction 2008, Candidate of Medical Sciences Sergeev, Vasily Yuryevich

  • The effectiveness of systemic antimicotic therapy of complicated forms of onchomicosis due to TRICHOPHYTON RUBRUM, taking into account the data analysis of cellular and humoral immunity 2009, Candidate of Medical Sciences Ayrapetyan, Narine Rubenovna

  • Mycoses Stop in patients with diabetes mellitus 2006, Candidate of Medical Sciences Belova, Sofia Georgievna

Conclusion of dissertation skin and Venereal Diseases, Hismatulina, Irina Mansurovna

1. In the structure of the dermatological morbidity of the population of the Republic of Tatarstan, there is a high proportion of fungal lesions of the skin and nails (27.8%). Mycoses Stop make up 75.3%. The main pathogens are dermatomycetes, which are presented by Trichophyton SPP.: TRICHOPHYTON RUBRUM (48.1%) and TRICHOPHYTON MENTAGROPHYTES VAR. Interdigitale (13.8%). It is traced a reliable increase in the number of highlighted fungal associations with an increase in the age of patients (p<0,05). Самыми весомыми грибковыми ассоциациями являются сочетания дерматомицетов с дрожжеподобными грибами (32,8%), преимущественно с Candida albicans.

2. The clinical manifestations of Mycoses of the Stop in the Republic of Tatarstan are characterized by a large specific weighing of their complicated forms - 14.8%. The following structure of complicated forms is determined: the presence of a secondary infection - 62.0%, ancate - 30.5%, the presence of Mikids is 7.5%. In a third of patients with onychomicosis, the stop (32.1%) defines the values \u200b\u200bof the cyotos from 20 to 30.

3. The use of natural terpeneoids (the drug "Abisciil", registration No. 003339/02) in the complex treatment of complicated forms of mycoses stops its efficiency. The timing of etiological and clinical cure is reduced by 2.0 ± 0.7 and 3.3 ± 0.6 days, respectively.

4. In patients with mikosami, a stop, complicated secondary infection, disorders of the cellular immunity in the form of reliable (p<0,01) снижения абсолютного количества Т-лимфоцитов (CD3+) и Т-хелперов (CD3/4+), увеличения лейкоцитарно-Т-лимфоцитарного индекса. Проведенная комплексная коррекция препаратом «Иммунал», совместно с наружным лечением микоза стоп, показала свою эффективность.

5. Hepatotoxicity and nephrotoxicity when using the Abiel preparation in the complex treatment of complicated forms of mycoses, stop was observed.

1. Most often by the pathogens of Mycoses of Stop in the Republic of Tatarstan are dermatomycetes represented by Trichophyton SPP.: TRICHOPHYTON RUBRUM - (48.1%) and TRICHOPHYTON MENTAGROPHYTES VAR. Interdigitale - (13.8%). An increase in the specific weight of the fungi associations is noted: Trichophyton SPP., (Trichophyton Rubrum and Trichophyton Mentagrophytes Var. Interdigitale) and Candida Albicans, as well as combinations of Trichophyton SPP. With Aspergillus Niger and Penicillum Chrysogenum. Further monitoring of the definition of causative agents of Stop myozes in the Republic of Tatarstan in order to optimize etiological treatment is necessary.

2. In the etiological structure of mycoses, the stop is a significant dependence of the frequency of identification of fungal associations from the age of patients (p<0,05), при этом определено, что у пациентов старше 60 лет их наличие в 2 - 6 раз больше, чем в возрастной группе до 29 лет. Это диктует необходимость усиления внимания врачей к больным пожилого возраста.

3. In a third of the patients (32.1%), the Kiotos values \u200b\u200bare defined from 20 to 30, which indicates the launched forms of onychomicoses that require long-term systemic therapy and removal of the nail plate, which causes the need to enhance educational work on the problem of mycoses among the population.

4. The use of the drug "ABISILE" in therapy of complicated forms of mycoses of STOP 2.0 ± 0.7 days reduces the terms of etiological and 3.3 ± 0.6 days of clinical cure. This makes it possible to recommend it in the local complex treatment of complicated forms of copies of the STOP in practical health care.

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