Miramistin spray- antiseptic for external and topical application... Miramistin has a pronounced bactericidal effect against gram-positive and gram-negative, aerobic and anaerobic bacteria in the form of monocultures and microbial associations, including hospital strains with multi-resistance to antibiotics.
The drug is more effective against gram-positive bacteria, acts on the causative agents of sexually transmitted diseases (Chlamydia spp., Treponema spp., Trichomonas vaginalis, Neisseria gonorrhoeae), as well as on herpes viruses, human immunodeficiency.
It has an antifungal effect, is active against ascomycetes of the genus Aspergillus and the genus Penicillium, yeast fungi (Rhodotorula rubra, Torulopsis gabrata, etc.), yeast-like fungi (Candida albicans, Candida tropicalis, Candida krusei, etc.), dermatophytes (Trichophyton rubrum, Trichophyton mentagrophytes, Trichophyton verrucosum, Trichophyton schoenleini, Trichophyton violacent, Epidermophyton Kaufman-Wolf, Epidermophyton floccosum, Microsporum gypseum, Microsporum canis, etc.), as well as on other pathogenic fungi, such as PURFORSE or PURSE in the form of monocultures and microbial associations, including fungal microflora with resistance to chemotherapeutic drugs.
Effectively prevents infection of wounds and burns, activates regeneration processes. It has a pronounced hyperosmolar activity, as a result of which it relieves wound and perifocal inflammation, absorbs purulent exudate, contributing to the formation of a dry scab. Does not damage granulation and viable skin cells, does not inhibit marginal epithelization. Does not have a local irritating effect and allergenic properties.

Indications for use

Miramistin spray for local use: prevention of suppuration and treatment of purulent wounds in the surgical and obstetric practice; superficial and deep burns; inflammatory diseases of the female genital area; individual prevention of sexually transmitted diseases (syphilis, gonorrhea, trichomoniasis, chlamydia, genital herpes, genital candidiasis); acute and chronic urethritis and urethroprostatitis of a specific and non-specific nature; periodontitis, stomatitis, hygienic treatment of removable dentures; acute and chronic otitis media, sinusitis, tonsillitis, laryngitis (as part of complex therapy).

Mode of application

With preventive and therapeutic purpose 0.01% Miramistin spray miramistin irrigate the surface of wounds and burns, loosely tampon wounds and fistulous passages, fix gauze tampons moistened with an antiseptic. The treatment procedure is repeated 2-3 times a day for 3-5 days. A highly effective method of active drainage of wounds and cavities with a daily consumption of about 1 liter of the drug.
Obstetrics and gynecology: In order to prevent puerperal infection, it is used in the form of vaginal irrigation before childbirth (5-7 days), in childbirth after each vaginal examination and in postpartum period 50 ml of the drug in the form of a tampon with an exposure of 2 hours for 5 days. When delivering women by caesarean section, immediately before the operation, the vagina is treated, during the operation, the uterine cavity and the incision on it are processed, and in postoperative period tampons moistened with 50 ml of solution are introduced into the vagina with an exposure of 2 hours for 7 days. Treatment of inflammatory diseases of the female genital organs is carried out in a course for 2 weeks by intravaginal injections of tampons with an antiseptic, as well as organ electrophoresis of the drug.
Venereology: For the prevention of sexually transmitted diseases, Miramistin is effective if it is used no later than 2 hours after intercourse. Using a nozzle, insert the contents of the bottle into the urethra for men (2-3 ml), women (1-2 ml) and into the vagina (5-10 ml) for 2-3 minutes. Treat the skin of the inner surfaces of the thighs, pubis, genitals. It is not recommended to urinate for 2 hours after the procedure.
Urology: Complex treatment of urethritis and urethroprostatitis is carried out by injecting 2-3 ml of 0.01% Miramistin solution into the urethra 1-2 times a day, course - 10 days, procedures every other day.
Otorhinolaryngology: In acute and chronic purulent otitis media by injecting the drug into paranasal sinuses nose. At purulent sinusitis- during puncture, the maxillary sinus is flushed with a sufficient amount of antiseptic. Tonsillitis and laryngitis are treated with multiple gargling with a solution of the drug.

Side effects

Local reactions: rarely - a burning sensation at the site of application (disappears on its own within 10-15 seconds and does not require discontinuation of the drug).

Contraindications

:
Hypersensitivity to the drug.

Pregnancy

:
Possible appointment Miramistin spray during periods of pregnancy and lactation according to indications, t. to. when applied topically and locally, systemic absorption of the active substance is unlikely.
In experimental studies, teratogenic and embryo toxic effect the drug has not been identified.

Interaction with other medicinal products

With the simultaneous use of the drug Miramistin spray with antibiotics, a decrease in the resistance of microorganisms to the latter was noted.

Overdose

:
Overdose data Miramistin spray no.

Storage conditions

Miramistin spray should be stored at room temperature.

form of issue
Solution for local application 0.01%: in polyethylene bottles with a urethral nozzle, 100 ml or in polyethylene bottles, 200 ml, equipped with a spray pump; in a box 1 bottle, or in polyethylene bottles of 500 ml.

Compound

:
1 ml of solution contains 0.1 mg miramistin.

Main settings

Name:

MIRAMISTIN spray

Family doctor, nutritionist. Head of a branch in the “Healthy Generation” medical network.

Miramistin is used according to the instructions for use in various fields of modern medicine. Antibacterial effect of the product broad action evaluated by surgeons, obstetricians-gynecologists, ENT doctors, pediatricians.

The drug Miramistin is used for the prevention and treatment of infectious lesions:

• wounds, burns, cracks, cuts, abscesses and other skin defects;
• mucous membrane of the oral and nasal cavity, pharynx;
• vulva, vagina, cervix, endometrium and urethra in women;
• urethra, prostate in men;
• prevention of diseases transmitted through sexual contact.

The drug is used topically:

• for prevention and treatment, the wound surface is irrigated 2-3 times a day for 3-5 days;
• for stomatitis, gingivitis and periodontitis, rinse your mouth with 10-15 ml of solution 3-4 times a day;
• for tonsillitis, pharyngitis and laryngitis, gargle / irrigate the throat 3-4 times a day, for irrigation, press the spray nozzle 3-4 times, for rinsing, use 10-15 ml of liquid;
• for the complex treatment of urethritis and urethroprostatitis, 2-3 ml of an antiseptic is injected into the urethra 1-2 times a day for 10 days;
• for the prevention of postpartum infections, tampons are used for 5 days, which are soaked in disinfectant solution for 2 hours.

Contraindication in adults is individual intolerance. The drug is used externally for:

• elimination of a wide range of bacteria, viruses, fungi;
• stimulation of healing;
• reducing the effusion of exudate;
• activation of local immunity.

Two forms of the drug are produced - a solution of 0.01% with a volume of 50/150/500 ml for external use with nozzles and an ointment 0.5% in a tube of 15 g.

Miramistin - instructions for use for the throat

The drug is used in the complex therapy of inflammation of the tonsils and throat - laryngitis, tonsillitis, pharyngitis. The throat is gargled or irrigated with a spray nozzle. The procedures are carried out 3-4 times a day, the course of treatment is from 10 days. Dose for one rinse - 10 ml, for spraying - 3 puffs.

It is rational to use a spray nozzle or a spray pump that turns a liquid into a spray:

1. Remove the protective cap from the bottle.
2. Remove the spray nozzle from the package.
3. Attach the nozzle to the neck of the bottle.
4. Test the nozzle by pressing once.
5. Irrigate the pharynx and tonsils evenly.

After using the spray pump, put the protective cap on the bottle. Store in a cool place, away from moisture and sunlight.

Miramistin for throat - price

For throat treatment, 150 ml solutions with a pump or irrigation nozzle or 500 ml for gargling are intended. The cost of Miramistin is:

• a 150 ml bottle with a spray nozzle - 350 - 390 rubles;
• a 150 ml bottle with a spray pump - 380 - 450 rubles;
• 500 ml bottle without attachments - 750 - 840 rubles.

Kseniya
22 years old

Throat rescue

16.11.2019 21:27

I am almost 24/7 outside in any weather, my throat often hurts. For all home-grown recipes like honey and garlic, I put a dislike. My number one for the throat Miramistin, I am saved only by them for 2 years. The price is not the lowest, but it is better to spend money on effective remedy than throwing money on fuflomycins.

Dignity

Good for sore throat.

Tasteless.

Flaws

Price.

Nasally, the agent is used to treat sinusitis, acute rhinitis and chronic form... After the puncture, the maxillary sinus is washed.

At home for adults with a cold:

• clear the nose of discharge;
• insert the spray nozzle into the nostril and press 3-4 times;
• repeat on the other side.

Spray antiseptic 4 times a day for up to 2 weeks. The medicine envelops the nasal mucosa, eliminates microbial contamination, and helps to restore breathing.
In addition, you can inhale with an antiseptic. An ultrasonic inhaler breaks down large particles to microscopic ones, which prevents burns of the mucous surface. The procedure is carried out as follows:

1. Dilute 3 ml of antiseptic with 6 ml of pure water or saline. Do not store the prepared mixture. Prepare the solution immediately before use. Discard any unused leftovers.
2. Inhale the solution while sitting for 15 minutes. Breathe slowly and calmly.
3. After inhalation, do not eat or drink for 30-40 minutes.

Contraindications for inhalation with Miramistin:

• bronchial asthma;
• pulmonary or heart failure;
• decompensated diabetes the first type;
• pneumothorax;
• tuberculosis.

Miramistin in the nose for children is used for acute and chronic rhinitis, sinusitis.
For babies from birth to 3 years old, use an antiseptic, pipetting 1 drop into each nostril three times a day. The course of treatment is 5-7 days. If there is no improvement in a week, consult your pediatrician.

Children from 3 years old can irrigate the nasal cavity using a spray nozzle, following the recommendations:

• 3 - 6 years old, one press at a time;
• 7 - 14 years old, two clicks;
• from 14 years old, three clicks.

The nose is treated 3-4 times a day for a period of 5 to 10 days. There is discomfort from tingling in the nose. The possibility of allergies cannot be ruled out.

Mouthwash with Miramistin is shown:

• for the treatment of candidal stomatitis, gingivitis and periodontitis;
• for ;
• when installing implants and dentures.

After brushing your teeth and removing the prosthesis, rinse your mouth with 10-15 ml of the product for 2-3 minutes. After rinsing, refrain from drinking and eating for 30 minutes. Rinse three times a day. The course of treatment and prevention is 10-14 days. For rinsing, the optimal shape will be a 500 ml bottle, which costs about 800 rubles.

Miramistin - instructions for use during pregnancy

When applied externally, the drug does not enter the bloodstream and does not penetrate the placenta, therefore it does not have a toxic effect on the development of the fetus.
During pregnancy, Miramistin is used for:

• for treatment of wounds, burns, frostbite - bandages soaked in 0.01% solution of the drug are applied;
• therapy for rhinitis, nasal congestion - instill 1-2 drops up to 4 times a day;
• gargling with pharyngitis, tonsillitis, sore throat - 10-15 ml of medicine 4-6 times a day, after rinsing for 30-40 minutes, do not drink or eat anything;
• for the treatment of thrush (candidiasis) of the birth canal, douching with a disinfectant solution is carried out 2 times a day;
• elimination of fungal lesions of the skin of the feet, nails - moisten a cotton swab in a medicinal liquid and apply to the nail plate, fix with a bandage or adhesive plaster. Processing is carried out 2 times a day for 10-14 days.

The most pressing prenatal problem is the debridement of the birth canal:

1. Soak a cotton swab in 50 ml of the solution.
2. Insert into the vagina for 2 hours.
3. Repeat the procedure for 5 consecutive days.

Miramistin - instructions for use in gynecology

An antiseptic in gynecological practice is used for:

• candidiasis of the vulva and vagina;
• inflammation of the mucous membrane of the body of the uterus;
• postpartum infection.

You can soak a cotton swab with 50 ml of the drug and insert it intravaginally for 2 hours every day for 5-7 days. Or use a special gynecological irrigation nozzle complete with a bottle.

Miramistin in gynecology for douching

Douching is carried out with a solution from a 50 ml bottle with a gynecological and urological applicator:

1. Open the vial by removing the cap but leaving the urologic applicator.
2. take the gynecological attachment out of the packaging.
3. Attach the gynecological attachment without removing the urological applicator.
4. Wash the outside of your vagina with water. Do not use soapy water, it will deactivate the drug's effect.
5. Gently insert the tip of the nozzle into your vagina and press three times.
6. After the procedure, disconnect the nozzle, rinse and dry.

Douches once a day, the course of procedures is from 5 to 7 days.

The solution is actively used for intimate hygiene after unprotected intercourse for the prevention of:

• chlamydia;
• trichomoniasis;
• gonorrhea;
• syphilis;
• candidiasis;
• genital herpes.

Attention! it makes sense to spend no later than 2 hours from the moment of contact. Before use medicinal product wash the external organs with warm water and soap and rinse thoroughly.

Miramistin for women

1. Irrigate the vagina with 10 ml of the solution using a bottle with a gynecological nozzle.
2. Then remove the gynecological attachment and inject 1-2 ml of solution into the urethra using the urological applicator.
3. After the procedure, do not use the toilet for 2 hours.

If there is no gynecological attachment, blot the swab liberally with an antiseptic and insert it into the vagina for 2 hours.

Larissa
28 years

Remedy with a wide range actions

21.08.2018 14:47

Once, after a stormy party, I woke up in bed with a stranger. And not that he did not inspire confidence, but anything can happen. I found my Miramistin in the bathroom, they prescribed it to me from the thrush. It is a little unpleasant to enter into the urethra, it stings, but you can tolerate it. This time it carried over, the analyzes are clean, but I'm not looking for adventure anymore.

Dignity

Good antiseptic

Can be used for prevention

Flaws

Expensive

Miramistin for men

1. Pee so that sexually transmitted diseases (STDs) are released in the urine.
2. Wash your external genitals thoroughly with soap and water.
3. Treat the external organs with a swab dipped in an antiseptic.
4. Inject 2-3 ml of solution into the urethra using the urological applicator (included with the bottle) and hold for 2-3 minutes.
5. Drain the solution and rinse the penis.
6. Refrain from urinating for 2 hours.

George
32 years

A proven remedy

06.09.2018 19:29

I am a free man, trouble-free - I cannot refuse beautiful girl even if you do not have a latex agent with you. In such an unexpected situation, the antiseptic Miramistin comes to the rescue. I have never failed, unlike some friends.

Dignity

No smell

Sparingly spent

Does not sting or discomfort

Flaws

The price seems overpriced, but the large volume of the bottle (150 ml)

Children are prescribed a drug from the first days of life for treatment:

• skin wounds, burns, frostbite;
• inflammation of the pharynx, larynx, tonsils;
• runny nose, stuffy nose;
• stomatitis (thrush in the mouth);
• inflammation of the gums (gingivitis).

Prevention and treatment of skin infections is carried out by dressings 1-2 times a day with the application of napkins soaked in solution. In children from 3 years old, a throat is treated with a spray:

• from 3 to 6 years old - 1 injection;
• from 7 to 14 years old - 2 injections each;
• over 14 years old - 3 injections each.

Treatment with a throat antiseptic in children is carried out three times a day, in a course of 5 to 10 days or more as prescribed by a doctor.

To eliminate stomatitis, a cotton swab is moistened with a solution of the drug and cleaned the oral cavity from white bloom... Continue treatment until the symptoms disappear under the supervision of a physician.
The spray is suitable for children from 3 years of age. For babies under 3 years old, it is better to instill an antiseptic into the nose with a pipette. The medicine fights tonsillitis, pharyngitis, laryngitis, sinusitis, rhinitis.

The frequency of treatment with Miramistin spray of the oral or nasal cavity is 3 times a day. The treatment lasts 5-10 days. Preschoolers need just one press of the nozzle, younger schoolchildren need two, and high school students need three sprays.

The spray is obtained by putting a nozzle or a spray pump on a bottle with a 0.01% solution of the drug 50/150 ml by volume. Apply a spray to the throat, nose, urethra, vagina. For irrigation female organs and the urethra in women and men, there are gynecological and urological nozzles.

Spray Miramistin for women

Spray with a special gynecological spray is intended for antiseptic treatment of the vagina and external organs in women. After a shower, once a day, the vagina is irrigated with 3 injections of the product. The drug is suitable for the treatment and, candidiasis. The treatment-and-prophylactic course is designed for a week, unless otherwise prescribed by the attending physician.

Miramistin spray - price

The cost of the Miramistin spray depends on the dosage:

• 50 ml bottle with urological nozzle - 200-250 rubles;
• a 50 ml bottle with a spray nozzle for the nose and throat - 230-280 rubles;
• a 150 ml bottle with a spray nozzle for the nose and throat - 350-390 rubles.

According to user reviews, the price of the medicine corresponds to its quality.

Elena
35 years

Great remedy for nasal congestion

18.10.2018 19:21

His 12-year-old son often has a stuffy nose in autumn and winter. It is impossible to study normally, to play sports. We were treated with various pshikalki prescribed in the clinic, but only Miramistin helped. Now the son breathes freely through his nose, plays his favorite hockey. The price of the drug is average, comparable to the income of an ordinary family, and the spray is very economical

Dignity

It helps very well with a cold

Economical consumption

Convenient dispenser and spray bottle

Flaws

Not found

The ointment form of the antiseptic is called Miramistin-Darnitsa with 0.5% of the active substance in the composition. It is sold in an aluminum tube of 15 g. Ointment is used for processing:

• purulent wounds, bedsores, trophic ulcers;
• thermal injuries - burns, frostbite;
• postoperative sutures, fistulas;
• skin areas for transplantation;
• skin areas affected by streptococcus and staphylococcus;
• feet, nails, skin folds, with candidiasis, actinomycosis.

The ointment is used in children from birth, pregnant and lactating. The use of an antiseptic in people sensitive to its composition is excluded. Daily dose ointment should not exceed one hundred grams.

The ointment is spread in a thin layer over the lesion, covered with a sterile bandage on top. Or they apply the ointment to a sterile napkin and fix it with a bandage. Deep wounds are loosely filled with tampons with ointment. Dressings in the active phase of the wound process are performed every day, reducing the frequency of procedures to 2 times a week as healing progresses.

For skin infections, the affected areas are lubricated twice a day. Peel off before processing fungal nails nail plate... The course of antifungal treatment lasts up to 2 months.

A solution with 0.01% active ingredient is the most commonly used form of the drug. Available in 50/150 ml bottles with attachments for urology, gynecology, oral and nasal cavity treatment. With the help of a spray nozzle, the liquid takes the form of a spray and evenly irrigates the surface of the mucous membrane. The 500 ml bottle is sold without a nozzle, intended for rinsing oral cavity, as well as washing the maxillary sinuses after puncture in a hospital. Dosage of treatment with a solution with a spray nozzle:

• preschoolers from 3 years old - one injection;
• junior schoolchildren - two injections;
• from 14 years old and adults - three injections.

3-4 procedures are recommended per day. Average duration course 5-10 days. An antiseptic solution prevents and cures bacterial, fungal, viral lesions of the skin and mucous membranes of the mouth, throat, nose, genitals, urethra. Used to prevent genital infections after unprotected contact.

Drops for instillation in the eyes, nose, ears with the substance Miramistin are sold under the trade name Okomistin in a polymer dropper bottle of 10 ml. Used for conjunctivitis, otitis media, sinusitis, nasopharyngitis, keratitis, iridocyclitis, eye and eyelid injuries. Okomistin drops are contraindicated for children under 3 years old, pregnant and lactating women, as well as those prone to allergies to the active ingredient.

Okomistin is used:

• 1-2 drops are dripped into the eyes up to 4-6 times a day, continuing up to 7-15 days;
• 2-3 drops in the nose in each nostril 4-6 times a day for 2 weeks;
• in the ears, 5 drops 4 times a day, in a course of 10 days.

Wear contact lenses 15 minutes after instillation. Avoid contact of the pipette with skin and mucous membranes. If after 3-4 days of treatment the symptoms worsen, consult a doctor.

The drug is not produced in tablets. Have a similar antiseptic effect sulfa drugs eg Bactrim tablets. Bactrim is contraindicated in children under 6 weeks of age, pregnant and lactating. Take 1 tablet twice a day for a week. Helps in the treatment of pneumonia, genital infections and diseases urinary tract infectious etiology.

Miramistin - instructions for use - price

Price different forms Miramistina:

• drops Okomistin 10 ml - 150 -180 rubles;
• a 50 ml bottle with a spray pump - 200-250 rubles;
• 50 ml bottle with gynecological / urological attachment - 230-280 rubles
• a 150 ml bottle with a spray pump - 350-390 rubles;
• a bottle of 150 ml with a gynecological / urological nozzle - 380-450 rubles;
• a 500 ml bottle without a nozzle - 750-840 rubles.

The drug can be purchased both at stationary pharmacies and via the Internet.

Miramistin - analogues - instructions for use, price, reviews

There are no complete analogues of Miramistin, comparable in safety and scope of use. However, existing counterparts for external use are much cheaper. Comparative analysis of funds is presented in the table.

A drug	Active substance	Use by pregnant and lactating women	Application in children
Miramistin solution 0.01%	miramistin	maybe	from birth
Chlorhexidine solution 0.05%	chlorhexidine	maybe	carefully
Hexoral solution 0.1%	hexetidine	for compelling indications, a drug for astronauts. Then at home in the pharmacy I found out the price of this spray. Well, yes, the price is cosmic. I took furacilin tablets and prepared the solution itself, treated the wound. Everything healed perfectly Dignity Kills germs Convenient to apply thanks to the spray nozzle

Miramistin is a drug from the group of cationic antiseptics with anti-inflammatory, antimicrobial and local immunoadjuvant action. The local immunostimulating effect is associated with the activation of phagocytic cells (macrophages and phagocytes). It has a fairly wide spectrum of action and therefore can be used in the treatment of a wide variety of diseases.

The main action of Miramistin is aimed at combating streptococci, staphylococci. Also, the drug is active against gram-positive, gram-negative, spore-forming, asporogenic, anaerobic, aerobic bacteria. It is used in several fields of medicine, and high efficiency allows you to fight a variety of diseases of bacterial origin.

It has a detrimental effect on the causative agents of sexually transmitted diseases: gonococci, pale treponema, Trichomonas, chlamydia, as well as herpes viruses, human immunodeficiency viruses, etc.

The antiseptic drug Miramistin has been on the pharmacological market for a long time. It comes in several forms: ointment, solution, spray, each of which has a powerful effect in the fight against various pathogenic bacteria.

Miramistin photo

Spray for throat Miramistin is a domestic antiseptic with an extremely wide range of applications. Gynecology, urology, traumatology, venereology, surgical practice - this is an incomplete list of areas in which this drug is considered indispensable.

Composition and form of release Miramistin

The active substance has the official name Benzyldimethyl ammonium chloride monohydrate or miramistin. The medicine got its name precisely because of him.

The mechanism of the therapeutic action of Miramistin is based on its surface-active properties. Active substance is able to interact with lipids of membranes of pathogenic microorganisms. In this case, the antiseptic molecule practically penetrates into the membrane and contributes to its destruction. As a result of the vigorous activity of the antiseptic, the attacked cell dies.

Ointment - 15 g in tubes. 1 g of the ointment includes: miramistin - 5 g, disodium salt of ethylenediaminetetraacetic acid - 5 mg, water-soluble base.

Miramistin solution for external application and spraying in the throat of 0.01% in bottles of 0.1 l, 0.15, 0.2 l or 0.5 l. 1 ml of Miramistin solution contains 0.1 mg of Miramistin.

Indications for use Miramistin

Obstetrics and gynecology: prevention and treatment of suppuration of postpartum wounds, perineal and vaginal wounds; postpartum infections; inflammatory diseases of the genital organs (vulvovaginitis). Surgery, traumatology: local treatment of infected wounds of different localization and etiology; prevention of secondary infection of granulating wounds. Combustiology: treatment of superficial and deep burns of II and IIIA degrees, preparation of burn wounds for dermatoplasty. Dermatology, venereology: treatment and prevention of pyoderma and dermatomycosis, candidiasis of the skin and mucous membranes, mycoses of the feet. Otolaryngology: Miramistin is used for tonsillitis, purulent sinusitis, pharyngitis, with adenoids, as well as in the complex therapy of otitis media. Urology: complex treatment of acute and chronic urethritis and urethroprostatitis of a specific (chlamydia, trichomoniasis, gonorrhea) and non-specific nature. In dentistry, it is prescribed to prevent the treatment of infectious and inflammatory processes occurring in the oral cavity. Treatment with Miramistin is practiced for stomatitis (possibly used for stomatitis in children), gingivitis, periodontitis. In addition, removable dentures are processed with the tool.

It is recommended to use the drug for the treatment of superficial skin lesions to prevent infectious complications. Miramistin for children is prescribed for the prevention of fungi, treatment of stomatitis, tonsillitis, treatment of abrasions and wounds.

Instructions for use Miramistin, dosages

For prophylactic and therapeutic purposes, the surface of wounds and burns is irrigated with a solution of Miramistin, wounds and fistulous passages are loosely tamponed, gauze tampons moistened with the drug are fixed. The treatment procedure is repeated 2-3 times a day for 3-5 days. A highly effective method of active drainage of wounds and cavities with a daily consumption of up to 1 liter of the drug.

In the treatment of urethroprostatitis or urethritis, the solution is used intraurethrally. The dose is 2-5 ml 3 times a day.

If a person needs emergency prevention of venereal diseases, the genital external organs can be washed with the solution, treated with a cotton swab moistened with the solution. For this purpose, the contents of the bottle are injected into the urethra using a urological applicator for about a couple of minutes: men are prescribed 3 milliliters, and women are prescribed -2 ​​ml and up to 10 ml into the vagina. In addition, it is important to treat the skin of the pubis, inner thighs, and genitals with a solution. After such a procedure, you should not urinate for two hours so that the drug has time to take effect.

With purulent otitis media, 2 ml of the solution should be applied to the external auditory canal, with laryngitis and tonsillitis, rinse the throat with a solution 4-6 times a day, with sinusitis - after removing the pus, rinse the maxillary sinus abundantly.

Patients with stomatitis and other dental diseases are prescribed rinsing the mouth 3-4 times a day. How to rinse your mouth depends on the severity of the disease.

In ophthalmology, for therapeutic purposes, 1-2 drops of Okomistin are instilled into the conjunctival sac 4-6 times a day. V preventive purposes the drug is used 2-3 days before the operation, and within 10-15 days after the operation. Instill 1-2 drops into the conjunctival sac 3 times a day.

How many times can Miramistin be sprinkled down the throat?

For children, one press will be enough, but the procedure will need to be carried out 3-4 times a day, and for adult patients, 2-3 pressings will be required a similar number of times during the day. The duration of use of the drug should not exceed 10 days, but after 4 days of use, it can be concluded whether the therapy is yielding results.

Otitis externa is treated by washing the ear canal, injecting 2 ml of the drug. This will help prevent the development of internal otitis media. It is recommended to take a tampon, soak with the product and insert into the external ear canal, 3 to 4 times a day. Apply for complex treatment otitis media.

Ointment Miramistin

When treating purulent wounds and burns in the active phase of the wound process, the ointment is used once a day, and in the regeneration phase - once every 1-3 days, depending on the activity of cleansing and healing the wound. For deep infected wounds of soft tissues, the ointment is used in combination with antibiotics of general (systemic) action.

With common (extensive) forms of dermatomycosis, in particular rubromycosis, Miramistin ointment can be used for 5-6 weeks in combination with antifungal drugs systemic action, intended for oral administration. In case of fungal infections of the nails, before treatment with Miramistin-Darnitsa ointment, the nail plates are exfoliated.

Application features

The use of the drug is characterized by no effect on the ability to drive vehicles and engage in other potentially dangerous species activities requiring increased concentration of attention and speed of psychomotor reactions.

The use of alcoholic beverages does not in any way affect the local use of Miramistin solution or ointment.

Venereology. After treatment with Miramistin ® of the urethra, vagina, inner thighs, pubis and external genital organs, urination is not recommended for 2:00.

There was a slight decrease in the resistance of microorganisms to antibiotics at joint application the latter with Miramistin.
the effectiveness of Miramistin ointment increases if it is applied to the wound surface, previously washed with an aseptic solution.

Side effects and contraindications Miramistin

Sometimes after using Miramistin, a mild and not very long burning sensation occurs, which, in fact, is its only side effect. The burning sensation goes away on its own after a while and practically does not cause serious discomfort.

Hypersensitivity reactions, including the phenomenon of local skin irritation: itching, hyperemia, burning sensation, dry skin.

There are no data on an overdose of the drug Miramistin.

hypersensitivity to the components of the drug; childhood up to 3 years.

There is no data on the safety of the drug during pregnancy and lactation.

Analogues Miramistin, list of drugs

Miramistin's analogs are drugs

Chlorhexidine, Dekasan, Octenisept, Okomistin, Septomirin.

Important - instructions for the use of Miramistin, the price and reviews do not apply to analogues and cannot be used as a guide to the use of drugs of similar composition or action. All therapeutic appointments must be made by a doctor. When replacing Miramistin with an analogue, it is important to consult a specialist, you may need to change the course of therapy, dosages, etc.

Do not self-medicate!

Miramistin is an antiseptic that was developed in our country and is able to fight various microorganisms, including bacteria, fungi, protozoa. Also, the drug is able to stimulate the immune system. Miramistin is included in the radar (register medicines) In Russia and is sold in pharmacies without a prescription.

The active substance is benzyldimethylammonium chloride, which belongs to the category of surfactants (surfactants). The compound was developed in the late 1970s in the Soviet Union. It was supposed to be used to disinfect spaceships during extended flights. However, in the early 1990s, the drug became available to the general consumer.

Miramistin has three main types of action:

• Antiseptic
• Immunostimulating
• Acceleration of wound healing

The mechanism of the antiseptic effect of the substance is based on the fact that it affects the lipid walls of the cells of microorganisms. In this case, the permeability of the walls is violated and microbes die. The drug is not toxic to the cells of the human body.

The immunostimulating effect is associated with the ability of the drug to increase the activity of phagocytes and macrophages.

The positive effect on wound healing is explained by the fact that Miramistin can serve as an absorbent substance that removes pus and fluid that occurs during inflammation of wounds. At the same time, the product does not irritate healthy tissues and does not interfere with the growth of new tissues.

The drug is active against both gram-positive and gram-negative bacteria, bacteria that form spores, pathogens of sexually transmitted diseases such as syphilis and gonorrhea. It is able to successfully fight hospital strains of bacteria that are resistant to a wide range of antibiotics. Moreover, the drug is most effective against gram-positive bacteria - streptococci and staphylococci. It is also active against fungi - dermatophytes, actinomycetes, pathogenic yeasts. There is reason to believe that it is active against various viruses - the herpes virus and HIV. Some studies suggest this.

One of the beneficial qualities of Miramistin is that when used externally, it does not penetrate the skin. This means that it does not enter the circulatory system and does not accumulate in the body.

Compound

There are only two forms of the drug - spray solution and ointment. Miramistin in the form of a cream, gel and tablets is not available.

Miramistin solution consists only of the active substance and water. Several types of bottles are available - with a capacity of 50, 100, 150, 250 and 500 ml. Miramistin with a volume of 150 ml, 100 ml and 250 ml can be supplied with a spray attachment. The 50 ml and 100 ml vials can be supplied with a urological applicator. The concentration of the active substance in the solution is 0.01%.

1 g of dry matter of the ointment contains 5 mg of Miramistin.

Also, the ointment contains:

• proxanol 268
• macrogol 400
• macrogol 1500
• macrogol 6000
• disodium edetat
• propylene glycol
• purified water

Indications

It is used for disinfection of tissues, skin and mucous membranes located on the surface, as well as for the prevention of their infection with pathogens.

The scope of application of the drug is wide enough. It is used in the following areas of medicine:

• Traumatology
• Surgery
• Obstetrics
• Gynecology
• Venereology
• Dermatology
• Dentistry
• Otolaryngology

Diseases for which Miramistin is used:

• genital candidiasis
• genital herpes
• gonorrhea
• trichomoniasis
• mycoses
• syphilis
• streptoderma and staphyloderma
• bedsores
• trophic ulcers
• frostbite
• second and third degree burns
• fistulas
• urethritis
• urethroprostatitis
• postpartum infections
• laryngitis
• tonsillitis
• sinusitis

Contrary to popular belief, Miramistin is not very effective for hemorrhoids. It can only be used in the treatment of complications accompanying this disease - for example, cracks in anus... However, it does not affect the main cause of the disease - varicose veins veins. He is also unable to film. pain syndrome accompanied by hemorrhoids.

Both the ointment and the spray are used for children, especially when treating infections of the upper respiratory tract... However, it is not recommended to use the drug for children under 3 years of age.

Mode of application

With urethritis and urethroprostatitis, 5 ml of solution is injected into the urethra.

In the prevention of sexually transmitted diseases for women, up to 10 ml of solution is injected into the vagina, for men - 1 ml inside the urethra. This procedure should be carried out no later than two hours after sexual intercourse.

For the treatment of otitis media, 2 ml of the solution should be injected into the ear canal. You can also instill two drops of the drug into the passage 2-3 times a day.

In case of inflammation of the oral cavity - stomatitis and gingivitis, it is recommended to rinse the oral cavity with a solution of 10-15 ml 3-4 times a day.

At different types respiratory diseases - pharyngitis, tonsillitis, sinusitis, it is recommended to gargle with a solution. It is recommended to use 10-15 ml of solution for one rinse, the procedure should be carried out six times a day. Also at respiratory diseases for the treatment of cough, you can do inhalation with a solution. For this, the most suitable device for inhalation is a nebulizer. Inhalation should be done 3 times a day. For one inhalation, 4 ml of solution is needed.

The drug can be used to treat the common cold. For this, it is recommended to bury it in the nose. However, it should be borne in mind that the drug may be irritating to the nasopharyngeal mucosa.

Instructions for using the spray for colds

For diseases of the upper respiratory tract, it is also recommended to irrigate the oral cavity with a nozzle. To make a spray from a bottle, you need to remove the cap from the bottle, attach a nozzle to the bottle and activate it by pressing. One press releases 3-5 ml of solution. A similar procedure must be done when acute pharyngitis or exacerbation chronic tonsillitis.

Children 3-6 years old do the procedure with one press on the nozzle, children 7-14 years old - with two presses, children over 14 years old and adults - with 3-4 presses. The procedure should be carried out 3-4 times a day. The duration of the course is 4-10 days and depends on the severity of the disease.

It is best to start treatment when the infection has not yet spread - in this case, it will be most effective.

Instructions for using the ointment

When treating burns and wounds, the ointment must be applied in a thin layer to the surface of the wound or burned area of ​​the skin. Cover the wound with a bandage. It is recommended to apply the ointment once a day.

When treating deep infections, Miramistin therapy should be combined with antibiotics.

When treating skin diseases, such as ringworm, the ointment is applied to the affected area twice a day and covered with a gauze bandage. However, drug therapy should be accompanied by the use of antifungal agents.

Contraindications

The medicine is considered to be relatively safe. The main contraindication is individual intolerance to the main component of the drug. For the ointment, intolerance to its auxiliary components may also appear.

It should be noted that the drug has been used relatively recently and therefore has not yet accumulated sufficient information indicating its side effects and the degree of security. Therefore, it is not recommended to use Miramistin during pregnancy and lactation. If there is an urgent need to use the drug during these periods, then treatment should be carried out after consulting a therapist.

The same can be said about the use of Miramistin for the treatment of children. To date, there is no sufficient evidence base on the safety of the drug for children. Therefore, the manufacturer does not recommend using it for the treatment of children under 3 years of age. If such a need arises, then in this case it is best to consult a pediatrician.

Unfortunately, the instructions for use of Miramistin are not described possible consequences drug intake into the digestive tract. But when rinsing your throat with this remedy, this is inevitable. It is clear that an adult will not intentionally swallow the medicine, but when a child uses it, a similar situation may arise. And this is another reason why the use of Miramistin for children may be unsafe.

Side effects and interactions with other substances

The drug has few side effects. Sometimes a burning sensation may occur when applied to the skin. However, this phenomenon usually goes away quickly. It cannot be a reason for discontinuation of the drug. Avoid getting the drug in the eyes. For the treatment of eye diseases, Okomistin drops are produced containing the same active ingredient.

No negative interactions with other drugs were found in Miramistin. With the simultaneous use of other antibiotics, Miramistin is able to enhance their effect. Anionic surfactants (soap solutions) can reduce the effect of the drug.

Analogs

There are few structural analogues of the drug at the moment. This:

• Miramistin-Darnitsa
• Eye drops Okomistin
• Septomirin

Among the funds that have a different composition, chlorhexidine is very close to Miramistin in terms of action and spectrum of application. The price of Miramistin is higher, but it has fewer contraindications. In addition, Miramistin has not been used for so long clinical practice, which means that fewer microorganisms managed to develop resistance to it.

Date of introduction December 13, 2007 Order of the Federal Service
on supervision in the field of health care and social development dated 13.12.2007 No. 4785-Pr / 07

Instructions for use of the drug Miramistin

Registration number:	R N001926 / 01
Tradename:	Miramistin ®
Chemical name:	Benzyldimethyl ammonium chloride monohydrate
Dosage form:	solution for topical use.
Compound:	active substance: benzyldimethyl ammonium chloride monohydrate (Miramistin, in terms of anhydrous substance) - 0.1 g, excipient: purified water - up to 1 liter.
Description:	colorless, transparent liquid, foaming on shaking.
Pharmacotherapeutic group:	antiseptic.

ATX code:

PHARMACOLOGICAL PROPERTIES OF THE PREPARATION MIRAMISTIN

Miramistin has a wide spectrum of antimicrobial activity, including hospital strains resistant to antibiotics.
The drug has a pronounced bactericidal effect against gram-positive ( Staphylococcus spp., Streptococcus spp., Streptococcus pneumoniae, etc.), gram-negative ( Pseudomonas aeruginosa, Miramistin can be used for children in the processing of toys and other contact objects. "> Escherichia coli, Klebsiella spp., Etc.), aerobic and anaerobic bacteria determined as monocultures and microbial associations, including hospital strains with multidrug resistance to antibiotics.
Has antifungal effect on ascomycetes of the genus Aspergillus and genus Penicillium, yeast ( Rhodotorula rubra, Torulopsis gabrata etc.) and yeast-like mushrooms ( Candida albicans, Candida tropicalis, Candida krusei, Pityrosporum orbiculare (Malassezia furfur), etc.), dermatophytes ( Trichophyton rubrum, Trichophyton mentagrophytes, Trichophyton verrucosum, Trichophyton schoenleini, Trichophyton violacent, Epidermophyton Kaufman-Wolf, Epidermophyton floccosum, Microsporum gypseum, Microsporum canis etc.), as well as other pathogenic fungi, in the form of monocultures and microbial associations, including fungal microflora with resistance to chemotherapeutic drugs.
It has an antiviral effect, is active against complex viruses (for the prevention of influenza, medical antiseptics are actively used. "> Herpes viruses, prevention after casual contacts is possible with the use of the antiseptic agent Miramistin"> human immunodeficiency virus, etc.).
Miramistin acts on sexually transmitted pathogens ( Chlamydia spp., Treponema spp., Trichomonas vaginalis, Neisseria gonorrhoeae, etc.).

Effectively prevents infection of wounds and burns. Activates regeneration processes. Stimulates defensive reactions at the site of application, due to the activation of the absorption and digestion functions of phagocytes, potentiates the activity of the monocytic-macrophage system. It has a pronounced hyperosmolar activity, as a result of which it relieves wound and perifocal inflammation, absorbs purulent exudate, contributing to the formation of a dry scab. Does not damage granulation and viable skin cells, does not inhibit marginal epithelization.
Does not possess local irritating effect and allergenic properties.
Pharmacokinetics. When applied topically, miramistin does not have the ability to be absorbed through the skin and mucous membranes.

Indications for use

Otorhinolaryngology: complex treatment of acute and chronic otitis media, sinusitis, tonsillitis, laryngitis, pharyngitis. In children aged 3 to 14 years, it is used for the complex treatment of acute pharyngitis and / or exacerbation of chronic tonsillitis.

Dentistry: treatment and prevention of infectious and inflammatory diseases of the oral cavity: stomatitis, gingivitis, periodontitis, periodontitis. Hygienic treatment of removable dentures.

Surgery, traumatology: prevention of suppuration and treatment of purulent wounds. Treatment of purulent-inflammatory processes of the musculoskeletal system.

Obstetrics-Gynecology: prevention and treatment of suppuration of postpartum injuries, perineal and vaginal wounds, postpartum infections, inflammatory diseases (vulvovaginitis, endometritis).

Combustiology: treatment of superficial and deep burns of II and IIIA degrees, preparation of burn wounds for dermatoplasty.

Dermatology, Venereology: treatment and prevention of pyoderma and dermatomycosis, candidiasis of the skin and mucous membranes, mycoses of the feet. Individual prevention of sexually transmitted diseases (syphilis, Miramistin's instruction contains a sequence of actions for emergency prevention of gonorrhea. "> Gonorrhea, chlamydia, trichomoniasis, genital herpes in the intimate area). a person begins to develop antibodies that prevent HSV from actively multiplying. "> herpes, genital candidiasis, etc.).

Urology: complex treatment of acute and chronic urethritis and urethroprostatitis of a specific (chlamydia, trichomoniasis, gonorrhea) and non-specific nature.

Contraindications Individual intolerance to the drug.

METHOD OF APPLICATION AND DOSE OF THE PREPARATION MIRAMISTIN

The drug is ready for use.

Instructions for using the spray pack:

1. Remove the cap from the bottle, also remove the urological applicator from the 50 ml bottle.
2. Remove the supplied spray nozzle from the protective packaging.
3. Attach the spray nozzle to the bottle.
4. Activate the spray nozzle by pressing again.

Directions for use of the 50 ml or 100 ml pack with a gynecological attachment:

1. Remove the cap from the bottle.
2. Remove the enclosed gynecological attachment from the protective packaging.
3. Attach the gynecological attachment to the bottle without removing the urological applicator.

Otorhinolaryngology.

With purulent sinusitis - during puncture, the maxillary sinus is flushed with a sufficient amount of the drug.

Tonsillitis, pharyngitis and laryngitis are treated by gargling and / or irrigation with a spray nozzle, 3-4 times pressing, 3-4 times a day. The amount of the preparation for one rinse is 10-15 ml.

In children. In case of acute pharyngitis and / or exacerbation of chronic tonsillitis, irrigation of the pharynx is carried out using a spray nozzle. Children aged 3-6 years: by pressing once on the head of the spray nozzle (3-5 ml per irrigation), 3-4 times a day; children aged 7-14 years by double pressing (5-7 ml per irrigation), 3-4 times a day; children over 14 years old 3-4 times pressing (10-15 ml for one irrigation), 3-4 times a day. The duration of therapy is from 4 to 10 days, depending on the timing of the onset of remission.

Dentistry.

For stomatitis, gingivitis, periodontitis, it is recommended to rinse the mouth with 10-15 ml of the drug, 3-4 times a day.

Surgery, traumatology, combustiology.

For prophylactic and therapeutic purposes, the surface of wounds and burns is irrigated, wounds and fistulous passages are loosely tamponed, gauze tampons moistened with the preparation are fixed. The treatment procedure is repeated 2-3 times a day for 3-5 days. A highly effective method of active drainage of wounds and cavities with a daily consumption of up to 1 liter of the drug.

Obstetrics, gynecology.

In order to prevent postpartum infection, it is used in the form of vaginal irrigation before childbirth (5-7 days), in childbirth after each vaginal examination and in the postpartum period, 50 ml of the drug in the form of a tampon with an exposure of 2 hours for 5 days. For the convenience of vaginal irrigation Miramistin irrigation is also used in the treatment of many diseases.

When women are delivered by cesarean section, immediately before the operation, the vagina is treated, during the operation - the uterine cavity and an incision on it, and in the postoperative period, tampons moistened with the drug are inserted into the vagina with an exposure of 2 hours for 7 days. Treatment of inflammatory diseases is carried out in a course of 2 weeks by intravaginal administration of tampons with the drug, as well as by the method of drug electrophoresis.

Venereology.

For the prevention of sexually transmitted diseases, the drug is effective if it is used no later than 2 hours after intercourse. Introduce the contents of the vial with an urological applicator into for men, Miramistin must be injected. "> the urethra for 2-3 minutes: for men (2-3 ml), for women (1-2 ml) and in the vagina (5-10 ml). For convenience, it is recommended to use a gynecological nozzle. Treat the skin of the inner thighs, pubis, genital organs After the procedure, it is recommended not to urinate for 2 hours.

Urology.

In the complex treatment of urethritis and urethroprostatitis, 2-3 ml of the drug is injected into the urethra 1-2 times a day, the course is 10 days.

Side effect.

In some cases, a slight burning sensation may occur at the site of application, which disappears on its own, after 15-20 seconds, and does not require discontinuation of the drug. Allergic reactions.

Interaction with other medicinal products.

When used simultaneously with Miramistin, it is not an antibiotic "> antibiotics, an increase in their antibacterial and antifungal properties has been noted.

Forms of release of Miramistin.

• Solution for topical application 0.01%.
• Polyethylene bottles with urological applicator with a screw cap 50 ml, 100 ml.
• Polyethylene bottles 50 ml with a urological applicator with a screw cap, complete with a spray nozzle.
• Polyethylene bottles 50 ml, 100 ml with a urological applicator with a screw cap, complete with a gynecological nozzle.
• Polyethylene bottles 100 ml, 150 ml, 200 ml complete with a spray nozzle or equipped with a spray pump and a protective cap.
• Polyethylene bottles 500 ml with screw cap with first opening control.