Helicobacter Pilori It is a unique malicious bacterium that causes a serious Helicobacteriosis disease. That dangerous disease The stomach is also characteristic of duodenal gut. This unusual bacterium lives in a special pyloric stomach department, due to which it has become so called. It has been proven that it easily opposes the powerful destructive action of a typical acidic acidity of the stomach. With the help of its flagellation, this bacterium is easily moved in the mucous walls of the stomach, and can also be fixed on them.

Helicobacter Pilori causes numerous diseases gastrointestinal tract. In reproduction, these microorganisms destructively affect all stomach cells, which leads to different inflammatory processes. These include not only gastritis and ulcers, but also cancer. To date, the destruction of such dangerous bacteria allows preventing the inevitable development of many pathologies.

Features of bacteria Helicobacter

It is the features that determine the impressive "survivability" Helicobacter.

The first feature is bacterium capable of withstanding a very acidic gastric medium. The main part of bacteria and viruses in conditions of such a high acidity dies. Helicobacter pylori is adjusted to increased acidity due to the use of two mechanisms:

The second feature is precisely Helicobacter, as already mentioned earlier, is the main provocateur of the diseases of the gastrointestinal tract. In the process of its reproduction, bacteria begins to destroy the stomach cells. And harmful substances that highlight the Helicobacter provoke chronic inflammation and gastritis. Due to the weakening of the mucous membrane of the duodenum and the stomach, multiple ulcers and erosion arise, the risks of development of oncology are significantly increasing. To date, scientists with confidence argue that it is Helicobacter that is the main cause of the stomach cancer.

You can get rid of infection by passing a course of treatment with antibacterial medical drugs that regulate the level of acidity of the stomach. Therapy should be appointed exclusively by the gastroenterologist, after passing all the necessary research.

Causes of infection of Bacteria Helicobacter

Bacterium Helicobacter Pilori cannot live outdoors, it is transmitted in most cases orally. In addition, infection can occur by:

• close physical contact;
• non-compliance with the banal rules of personal hygiene;
• poor quality processing of medical instruments;
• use of common utensils;
• cough, sneezing.

As medical practice shows, the leading cause of penetration into the organism pathogenic microflora is non-compliance with personal hygiene rules. Infection is no less common due to admission to food incorrectly processed, not washed fruits and vegetables.

The fecal-oral path is the main way to get infections. Despite the effects of hydrochloric acid, the microflora does not die. Bacteria is movable, more wow, it is attached to the walls of the stomach.

When penetrating the chelicobacter into the mucous membranes occurs, the tissue destruction occurs, and as a result, the development of other pathological processes.

Microorganism can provoke an emergence:

• pathologies of the endocrine system;
• gastritis;
• cancer;
• ulcers;
• cholecystitis.

It also relies that from the helicobacteriosis, coronary heart disease can develop.

Main symptoms in the body of bacteria Helicobacter

The main symptoms of Helicobacter Pilorary affect functioning digestive system. Gastroenterologist will tell what signs should pay attention to. Usually there are several of them. The main are:

The more bacteria is present in the cavity of the stomach, the brighter the symptoms are expressed. So, with insignificant colonization, people complain only on light nausea. Gradually, unpleasant feelings are enhanced. The following symptoms appear in humans: the smell of mouth; white raids in language; sour taste in the mouth; constipation; drilling in the stomach; flatulence; heaviness in the stomach.

When Helicobacter, painful sensations arise. On the early stages They are easy to endure, but as the disease develops, the intensity of pain is enhanced. They acquire a sharp cutting character.

The smell of the mouth appears due to the vital activity of the microorganism. Bacteria, being in the stomach, produce ammonia. Another reason for the emergence of the smell of mouth - dysbacteriosis and violation of normal stomach motor, as well as constant belching.

If vomiting is joined by the smell of the mouth after food receptions, as well as a refusal of food, then the likelihood of the development of complications is high. At the same time, the patient rapidly lose weight.

Patients are often wondering whether bacterium can cause symptoms such as headaches, an increase in temperature or cough. Gastroenterologists believe that they are associated with other diseases. However, when wearing the ulcers and the spread of inflammation abdominal cavity There is a heat.

Additional symptoms of bacteria Helicobacter

A number of symptoms that are not directly related to digestion can cause cheelicobacter pylori, and the reasons for these signs are usually associated with the weakening of the immune system. A strong organism oppresses the life of a microbe, not allowing it to form a colony in internal organs. Helicobacter can provoke an atypical reaction. When they appear, the examination should be survened and assured.

• Allergic reactions. Helicobacter can affect skin. Allergic dermatitis It is often observed on the forehead and cheeks. The deterioration of the condition of the skin is one of the signs of infection Helicobacter. Pink acne can also be associated with this pathology;

• Alopecia. With a helicobacter infection, not only allergic appears. A person has hair loss. Often it has a nesting character. This symptom develops due to reducing immunity. Feeded hair - manifestation of avitaminosis. This feature arises due to the exhaustion of the body;

• Psoriasis. Skin problems throughout the body can also be symptoms of infection Helicobacter.

Helicobacteriosis is not a direct cause of infertility, but should not exclude its influence. The microorganism significantly depletes the body, bacteria are able to cause hypovitaminosis, which reduces fertility of a woman. The reason for the appearance of infertility may be a weak immune system. Infection Helicobacter Pilori is dangerous during pregnancy. Even if the colonization of microbes did not cause infertility, it is worth carefully observed for your well-being. Sometimes the disease provokes the familiar not to wear the fetus.

Diagnosis of bacteria Helicobacter

In some patients with disease, the Helicobacteriosis, certain symptoms may not be observed. To determine the presence of bacteria, special tests are used. Histological and special urease analysis is shown to identify Helicobacter Pilori.

A cytological study is based on the receipt of prints-prints that are taken with endoscopy, as well as for this procedure, the biopsyths of the mucous membrane of the special anthral gastric department are necessary. As a rule, Bioptat takes aiming from those areas where visually the most expressed deviations from the norms. A specialist in such regions can observe hyperemia and swelling. Often spiral-like helicobacteria are located in the center of the mucus.

Such a cytological study determines the three main degrees of dissemination of mucous bacteria. If there are less than 20 microbial bodies, a weak disgrace is diagnosed, which does not cause anxiety for human health. Cellular infiltration is also detected when microorganisms are detected in prints and plasma cells.

Depending on the number of certain cell elements, it is indisputable to judge the pronounced degree of activity and the inflammatory process. In addition, such a study reveals proliferative processes in mucous membranes, dysplasia and metaplasia, as well as various malignant education. However, the cytological method does not give the idea of \u200b\u200bthe structure of mucous membranes.

A special urease test is considered an effective express method, which is mainly based on the activity of the presented microorganisms. It is done using a special carrier gel containing urea, a special bacteriostatic agent and a special phenol-roller as the required indicator. Such a pH indicator allows you to make accurate conclusions about the specific state of the mucous membranes of the stomach. The bioptat of the mucous membrane obtained as a result of endoscopy is also placed in this test.

In extremely rare cases, the test shows false-negative results, which is possible with the weakness of helicobacter infection. To increase the reliability, experts usually use histological and urease methods. After the antibacterial treatment, they should be repeated. If necessary, a repeated course of combined antigelicobacter-type therapy can be assigned, which will avoid emergency recurrences of the disease.

Special respiratory test non-invasive and safe. It allows you to easily determine the level of colonization of population of the mucous microorganisms. Such an analysis is considered optimal for full-fledged control of eradication therapy. This study should be made on an empty stomach. First take special samples of background exhaled air, and then after a light breakfast use a test substrate.

Various histological methods are designed to quickly detect Helicobacteria in biopsy, allowing simultaneously to study morphological changes. The bright coloring method for gymzees is the most affordable and simple. With this test, the microorganisms are well visible on the surface of the epithelium and in the depths of the hole. Another histological method of accurate hybridization of DNA is sensitive and highly specific. It allows you to identify numerous strains Helicobacter Pilori.

Other techniques also apply for diagnostics. These include immunological and microbiological methods, polymerase chain reaction, as well as the definition of antigen in feces. As a rule, blood and results of endoscopy take on analysis, and also investigate breathing and feces.

Helicobacter bacteria treatment

Like most others infectious diseases, Treatment of bacteria Helicobacter pylori is carried out using antibiotics. This method of therapy is assigned in the event that the intended positive effect of drugs significantly exceeds potential harm. In view of this, medicia treatment It is appointed not in all cases, or is limited to the reception of drugs with less harmful influence on the body.

The main indication for receiving antibiotics is the presence of ulcers or erosions on the mucous membrane. Without the use of such drugs, further treatment will be ineffective. Reception of antibiotics is appropriate in the case of the development of complications, among which atrophic gastritis or gastric Maltoma. To prevent recurrences, therapy can be carried out even during remission.

For the treatment of Helicobacter infection, several antibiotics options are appointed. The reception is made in accordance with the established scheme, which is compiled individually for each patient. The use of antibiotics of different groups is necessary due to the fact that the bacteria Helicobacter Piluri is different high indicator Sustainability, that is, may be insensitive to the current components of the drug.

In the treatment of infection, drugs are also prescribed, the action of which is directed to the regulation of the acidity of the stomach. The most frequently used funds include preparations Pariet, Famotidin, Roxatidine, omeprazole. These drugs adjust the amount of acid produced in the stomach, due to the negative impact on ulcers. In turn, it accelerates the healing process, and also eliminates a number of symptoms, including heartburn and meteorism.

Also, the drug complex often includes preparations-prokinetics. Their action is aimed at restoring the normal intestinal motorcycle, due to which the processing and removal process from the body is improved. Reception of such tools allows you to get rid of constipation or diarrhea, eliminate nausea.

In general, the treatment of bacteria Helicobacter Piluri in most cases is aimed at the complete destruction of pathogenic microorganisms using antibiotics, but a more gentle therapy can be used without the use of such funds.

Folk methods for treating bacteria Helicobacter

• For 5 minutes, boil the flax seed. Give the champ in line for 2 hours, after profile. As a result, the mucus, which should be taken in 1 tbsp. daily before meals;

• Before meals, drink fresh potato juice in half a cup. This means effectively calms the stomach;

• If you do not have chronic gastritis, you can drink freshly squeezed cabbage juice in half a cup 1 hour before intake. The cabbage contains vitamin U, which helps to spend damage;

• Prepare juice from fresh plantain leaves. Take 1 tbsp. Juice with warm water 30 minutes before meals.

• Infusion of the root of AIR (with reduced acidity). The tablespoon of dried and crushed root is poured with a glass of boiling water, insist for several hours and used 100 ml before meals;

• Antimicrobial action has infusion from the Hypericum, the root of nine and the gold masculine. Herbs are used in equal proportions and brewed according to the standard scheme - by 250 ml of boiling water tablespoon of the mixture;

• Fighting with the bacterium will also help the mixture from the Hypericum, calendula and yarrow.

Prevention of bacteria Helicobacter

Since infection in most cases is transmitted from a sick person to healthy, it is necessary to strictly adhere to the rules of personal hygiene. In practice, such simple rules can be applied:

• eliminate smoking and minimize alcohol consumption;

• do not use someone else's dishes, personal hygiene subjects;

• after visiting public places, toilet needs to wash hands with soap.

There are no vaccination against this disease. But if you adhere to the prophylaxis rules, you can practically exclude the development of the pathological process in a healthy body.

Bacterium Helicobacter Pilori was detected for more than half a century ago in the mucous membrane of the stomach of man. It has been established that this microorganism provokes the development of gastritis, ulcers, erosions and polyps, as well as malignant tumors in the intestines and the stomach, so it will be very useful to find out how bacterium falls into our body and how to get rid of Helicobacter Pilori.

Causes of the appearance of Helicobacter Pilori

Infection with a dangerous microorganism occurs through contaminated food and water, as well as as a result of contact with the carrier of the bacterium. To get an infection, sometimes enough to eat dirty vegetables, do not wash your hands before eating or take advantage of someone else's dishes. Moreover, harmful microorganisms Transmitted through saliva or sputum, which is highlighted during coughing, while their important feature is the inability to exist in the air. It is also worth noting that Helicobacter Pilori is considered a family disease, since recent studies have proven that if at least one family members are infected with this microorganism, all other representatives will be infected with a probability of 95%.

Finding into the stomach, bacteria provokes the development of many hazardous diseases. This is due to the fact that the chylicobacter pylori is not amenable to the effects of hydrochloric acid, as a result, the microorganism penetrates deep into the mucous membrane of the stomach walls, thereby disrupting their protective properties. Bacteria can lead to gastritis, erosion, ulcers, stomach cancer, chivests, hepatitis, diseases of the endocrine system, skin inflammation and even ischemic Disease Hearts.

Symptoms Helicobacter Pilori

Often, a person may not even suspect that it is infected with a dangerous microbe. Helicobacter Pilori begins to activate during the period of weakening the body, after strong stress, angina or even a sharp change in the power mode, while the person begins to completely sound to be treated from various diseases, without understanding what happens to him. In fact, the main symptoms of Helicobacter Pilora are gastritis and ulcers, because this bacterium is the cause of their occurrence.

Be sure to pay attention to the following signs Helicobacter Pilori: Frequent constipation or diarrhea, allergic, excessive nail fragility and fungal diseases, unpleasant smell of mouth in the absence of problems with teeth, as well as hair loss.

In addition, the symptom of the presence in the body of a harmful bacterium is periodically repeated pain in the area of \u200b\u200bthe stomach, which, as a rule, stops after meals. It can be accompanied by such phenomena as heartburn, nausea, vomiting, poor digestibility of any meat products, severe gravity in the stomach.

Analysis for the presence of bacteria

Proper diagnosis of the disease is a necessary step towards recovery, because only due to it can be prescribed as much as possible. effective treatmentTherefore, in case of detection of any of the above symptoms, the chielicobacter pylori, it is necessary to quickly conduct a test for the presence of a harmful bacterium in the body. Modern diagnostic methods make it possible to avoid painful surveys, to identify microorganism will help an effective respiratory urease test, which has a sensitivity equal to almost 90%. However, note that for greater reliability of the result, before passing the procedure, it is necessary to clean not only the teeth, but also the language and even the throat.

In some cases, an immunofermental analysis is used to determine the chielicobacter, which is aimed at determining the presence of antibodies to the blood bacterium, however it is worth noting that this test can not be called too reliable. The method of polymerase chain reaction, which can identify the presence of a microorganism both in blood and in saliva, has much more reliability.

Treatment Scheme Helicobacter Pilora

To combat bacteria, antacid and substances are used, which reduce the amount of gastric juice produced, but these drugs cannot completely eliminate the chylicobacter pylori. Doctors know well that after the cessation of medication techniques caused by microorganism, they are almost always returned, so patients account for special drugs for years.

In fact, the complete destruction of harmful bacteria is a very difficult task, as they have extremely high resistance to antibiotics. In order to reliably eliminate the helicobacter pylori, it is necessary to combine the reception of several antibacterial drugs and blockers of proton pumps, as well as bismuth preparations. It is believed that such an approach helps patients about 80% of cases. It is worth noting that if the patient has previously taken any antibiotic, then bacteria may well be resistant to it, because the use of such a medication will not bring the desired result. Sometimes after the course of treatment, the patient assign analyzes to help determine how effective the drugs were produced. In this case, a respiratory test or feces analysis are carried out, which are necessary primarily to those patients in whom infection caused complications in the form of perforation of the gastric mucosa or bleeding.

Treatment with folk remedies

In order to most effectively cope with Helicobacter Pilori, it is necessary to apply an integrated approach and combine drug treatment with proper nutrition and effective means folk Medicinewhich are designed to normalize the acidity of gastric juice and remove pain in the stomach. All sorts of decoctions and fees affect both the cause of the disease and the process of occurring, while recipes differ depending on which type of acidity is observed in the patient.

So, when the following means is often used: the linen seed needs to be booked for five minutes, after which it is insisted for about two hours and profile. The resulting mucus should be given to the patient on one tablespoon before each meal intake. Extremely effectively lowers the acidity of infusion from herbal collection, which includes St. John's wort, chamomile, cleanliness and yarrow. To prepare a tool, mix an equal amount of ingredients, take 4 tablespoons of grass and pour it boiling water. Infusion must be left for several hours, after which it can be given to the patient in small quantities in half an hour before meals.

As for reduced acidity, in this case, in this case, an hour before meals, it is possible to consume a half-table of freshly squeezed cabbage juice, as well as decoction from AIR. For its preparation, four tablespoons of the rhizoma of the plant should be pouring a liter of boiling water, then give the means to stand around at half an hour and take it at a quarter of a glass to meals.

Get rid of painful sensations in the abdomen will help infusion of pear flowers, apple trees, strawberries and leaf lines, equal to the amount of which should be poured boiling water, cool, strain and drink between meals.

Diet in the treatment of Helicobacter Pilori

Although the main thing in the treatment of Helicobacter pylori is the reception of drugs, in no case do not forget about proper nutrition. So, the patient cannot be done too large intervals between the meals, while the food should be used exclusively in small portions. It is important to observe 5-6 one-time power regimen, and it is necessary to slowly, carefully chewing food, not forgetting to drink it with a sufficient amount of liquid.

The patient can not eat too fat, fried or acute food, it is better to abandon marinated dishes, carbonated drinks, and, of course, alcohol. In fact, it is only general recommendations, Indeed, in each particular case, the power is based on the level of acidity must be prescribed a specialist who conducts treatment.

Helicobacter Pilori - a dangerous microorganism that can lead to development serious diseases. In order to effectively cope with the problem, at the very first symptoms of the presence of this bacterium in the body, a special test should be passed and, if necessary, to do with complex treatment, which involves combining the achievements of people and classical medicine.

Helicobacteriosis is a pathology resulting from the vital activity of the bacterium Helicobacter pylori. It differs from all the microorganisms known to date of this group by the fact that it is capable of surviving in an acidic medium of the pyloric stomach. Her presence negatively affects human health. It is her who he owes diseases of the gastrointestinal tract.

Bacterium Helicobacter Pilorary provokes the appearance of inflammatory processes localizing in the mucous membranes of the gastrointestinal tract.

Thus, there are violations in the body, which over time and without proper treatment are becoming a serious cause for concern. Also, according to many professionals, it is Helicobacter Piluri that provoke malignant neoplasms diagnosed as cancer.

In the stomach or in the intestine, bacteria causes the appearance of tissue atrophy and the formation of an ulcers that, after can be reborn in cancer. Then the options will remain a bit.

The specified pathogen is striking regardless of sexuality, races and age. Unfortunately, the gastric juices do not act on it, but scientists work on the vaccine. Adults suffer from Helicobacteriosis are somewhat more common than older people or children. This is caused by their more active life position.

What is Helicobacter Pilori?

The exact mechanism of transmission and causes of the occurrence of helicobacteriosis is not known today, but a list of alleged ways of infection is drawn up.

These include:

1. the use of non-sterile medical instruments;
2. the presence of common items with a person who suffers from helicobacteriosis;
3. thickening thirst with water from under the tap;
4. consumption of unwashed fruits and vegetables;
5. non-compliance with personal hygiene norms;
6. transmission of bacteria by air.

The source of infection with the name "Helicobacter Pylori" may become a sick person or a bacterium carrier. The latter often does not suspect about his "mission", while once in its body does not identify the presence of "colonies" constructed by Helicobacter Pilori.

If at least one of the households is sick, then everyone else will acquire helicobacteriosis in the near future, infected from each other.

Helicobacteriosis symptoms

Bacterial infection It may proceed in different ways. Allocate two main forms. Bacteria Helicobacter, developing on latent type, does not give out symptoms characterized by unpleasant or painful sensations. This is possible only with a not weakened immune system. But even such a scenario has no good completion.

Because of the hidden development, the pathology is difficult to identify, so the fabrics that were atrophied atrophized became the cause of a malignant neoplasms. Many patients are confident to the latter that this is an intestinal virus that will soon disappear.

Scientists have proven that the bacterium Pilori, the symptoms of which are "silent", due to harmful dependencies and depressive disorders "Colonizes" the body is much faster.

The second form is called acute. She is often accompanied by pain in the stomach; nausea and vomit; heartburn, an unpleasant flavor; excessive release of gases; Bleeding gums. This is the defeat of the duodenum or stomach.

In the future, the sharp phase goes into chronic, which manifests itself with alternation of exhausting diarrhea and constipation; lack of interest in food; Hunger after meals or, on the contrary, overeating. Both are fraught with consequences.

In addition to these two forms, the development of ulcerative disease, gastroduodenitis and gastritis in chronic form is distinguished into a separate group. All these diseases indicate that bacteria in the stomach settled for a long time. The signs of each of these ailments have similarities and differences between themselves.

Helicobacter causes different symptoms that can even manifest on face. This pathology is called Rosacea.

What it is?

Its main symptom is the emergence of inflamed acne on the face and unpleasant odors from mouth. The reason is located in the area of \u200b\u200bthe stomach.

More than 80% of helicobacteriosis suffered from such violations in the body. An unpleasant feelings are complemented by aesthetic disadvantage, because of which many complexes appear.

Diagnosis of the disease

The presence of microorganism is diagnosed by means of specific laboratory studies, due to the lack of characteristic inherent in this disease, signs. But before they are prescribed to conduct a survey of the patient, its inspection, physical and endoscopic research.

Also carry out fibrogastroscopy, that is, they receive a sample of the atrophied tissue of the stomach (biopsy) by means of special equipment.

Analyzes are taken both for diagnosis and to control the progress of treatment. The identification of the exact cause is only possible after receiving the results of the study:

1. blood and saliva, taken in the case of bleeding gums;
2. feces for the presence of waste from the life of microorganisms;
3. blood for determining antibodies.

Diagnostic events also carry out a month or one and a half after the end of the antibiotics course. For loyalty, two methods use. A similar step allows you to more correctly determine the result of the therapy.

Helicobacteriosis therapy

How to treat bacteria Helicobacter pylori?

Medical procedures are carried out in order to eliminate the bacterium with all its "colonies" from the surface of the stomach and intestines. Therapy is selected individually for each patient. At the same time, the attending physician takes into account the severity of the disease, the zone of the defeat, which manifested the symptoms and the peculiarities of the body of the disease.

Most often, antibiotic drugs are used for treatment: "Metronidazole", "Amoxicillin", "Tetracycline", "Clarithromycin" and "Rabeprazole".

The duration of the course conducted by these drugs is about 14 days. The effect of therapy directly depends on the patient compliance with the recommendations of the attending physician and from already existing complications due to helicobacteriosis.

If he moved to chronic form, there is a danger of the formation of a malignant tumor, from which to get rid of it will be very difficult.

"Why am I treating antibiotics?" - Ask many patients.

The treatment diagram is developed by several specialists, among which there is an oncologist or a gastroenterologist, depending on which symptoms of Helico were formed.

Eradication type therapy characterized by comprehensive application selected by the attending physician drugs It is quite effective, as it causes persistent remission.

There are two treatment schemes. The first implies the reception of the drugs listed above, and for the second, three drugs from the previous line (Tetracycline, Metronidazole, Rabeprazole) and "Vismut subsalicylate" are used.

The course of treatment with this complex should not exceed two weeks. Such a treatment is designed to save the body from bacteria Helicobacter forever.

Antibiotics oppress the intestinal activity, so the patient with helicobacteriasis should be in parallel with drugs from the antibiotic group to use "bifiform" or "lines". Their function is to reduce the negative impact of basic drugs on the mucous membranes of the tract and restoration of its operation.

This arises due to the presence of soft active substances that do not irritate the mucous membrane.

The result arising after passing therapy is influenced by the form of pathology, the compliance of prescribed drug drugs available to the problems and reaction of bacteria Helicobacter pylori for the measures taken. If gastritis or ulcer of the stomach formed during the development of helicobacteriosis, then a complete recovery is possible.

When the oncology appears, everything is much more complicated. Siberia (absence of such an opportunity) of the tumor is of great importance. If you can delete it, then the chances of full recovery are quite high.

Powered for the period of treatment should change significantly. First, the therapy, carried out with the help of antibiotics, eliminates fat and acute food. Secondly, alcohol is also banned. He negates the whole therapeutic effect And negatively affects general well-being.

Phytotherapy, in turn, will help eliminate the alarming signs of infection of the Bacteria Helicobacter Pilori.

Use folk remedies It follows only after consulting with your doctor. If he agrees with the introduction of plant tools into the general treatment regimen, then you can start their reception.

Preolis-based drugs, pear flowers, pear flowers, yarrow, apple tree inflorescences, gold bars, berries and leaf lingers, calendulas, ninewood and beasts. They are consumed in the form of decoctions, infusions and tea.

Recipes dedicated to bacterial infection of the set. There is from what to choose, the main thing is not to forget to show them a specialist. The effect is not manifested immediately, by the end of the course you can already notice improvements.

We must not forget that the plant ingredients also have contraindications and side effects.

Preventive measures

Despite the difficulties associated with cheilicobacteriasis, prevention does not require much effort and time. Its rules are quite simple and everyone familiar.

To avoid this disease you need:

• to carry out personal hygiene to use only their devices;
• wash fruits and vegetables before meals;
• avoid touch and sharing items with unfamiliar people;
• comply with personal hygiene rules;
• abandon all harmful dependencies;
• be careful when choosing a sexual partner;
• contact B. medical institution In case of doubt about their health.

Immunity to this pathology is not produced, so the only way out of the situation is to prevent health problems by improving the quality of life. Make it can be done by yourself.

Calculation of alcohol and cigarettes, regular sports, a full-fledged rest - all this will help to improve the body, strengthen the immune system and look at the world with other eyes.

Helicobacter pylori. It is a pathogenic bacterium that dwells mainly in the pyloric (antrheral) stomach department.

The photo below shows that the microorganism has the form of a spiral, to which flagellas are attached. Such a structure helps her tightly hold onto the walls of the digestive organ, moving along it with mucus and exist in an acidic environment that many pathogenic microorganisms are not transferred and die.

Finding into the human body, Helicobacter Pilori causes a dangerous disease - helicobacteriosis. Bacteria rapidly multiply, and in the process of their livelihoods, many toxins produce, feeding the gastric mucosa (duodenum), and then the walls of the digestive organ. This impact is dangerous in that it creates a favorable environment for gastritis, ulcers, as well as malignant neoplasms.

What it is?

Helicobacter Pilori is just a bacterium, which is found in patients with various diseases Stomach and intestines, duodenum in particular.

As for the title of the bacterium, Helicobacter Pylori (Helicobacter Pylori), then it is not at all by chance. One part of it, "Pylory," indicates the main habitat of the bacterium - the pyloric department of the stomach, and the second part, "Helico", characterizes the shape of the bacteria: a screw-like, spiral-shaped.

Earlier in medicine it was believed that a microorganism capable of surviving in an acidic, hydrochloride of the stomach in principle does not exist. But then doctors did not suspect the existence of helicobacteria. Helicobacter Pilori was opened only in 1979 by scientists from Australia Robin Warren. Together with the scientist with a colleague, Dr. Barry Marshall "discoveries" managed to grow this bacterium Helicobacter in laboratory conditions. Then they only suggested that it was she who was the guilt of gastritis and a stomach ulcers, and not at all the wrong food or stress, as previously thought.

In an attempt to confirm the rightness of his guess, Barry Marshall conducted an experiment on himself, drinking the contents of Petri dishes, in which Helicobacter Pilori was cultivated. After literally a few days the scientist showed gastritis. It was able to cure it, taking the Metronidazole over two weeks. And already in 2005, the authors of this discovery scientists for their discovery were received by the Nobel Prize in Medicine. The whole world acknowledged that ulcers and gastritis, with all the resulting and related diseases, appear precisely because of helicobacteria.

How can I get infected?

Infection occurs when transmitting bacteria from one person to another fecal or oral or orally. In addition, there are hypotheses about transferring these bacteria from cats to a person, as well as their mechanical transfer of flies.

Most often infection occurs in childhood. The most likely by infection is considered to be the transfer of Helicobacter Pilori from a person to a person who can occur in three ways:

1. Yatrogenic (due to medical procedures) path. In this case, the infection is due to the use of endoscopic or other medical instrument, which in contact with the mucous membrane of the stomach of an infected patient, in another person.
2. Fecal-oral path. H. Pylori stand out with a chair of infected people. The source of infection can be contaminated called masses Water or food.
3. Oral oral path. There are evidence that Helicobacter Pilora may be in oral cavity. Therefore, it is possible to transmit bacteria when sharing cutlery and toothbrushes, kisses.

What happens in the body?

At the initial stage, after hitting the stomach H. pylori, quickly moving with flavors, overcomes the protective layer of mucus and colonizes the mucous membrane of the stomach. Purchased on the surface of the mucous membrane, the bacterium begins to produce uraase, due to which the concentration of ammonia is growing in the mucous membrane and a layer of protective mucos and a layer of a protective mucus and the ph. According to the negative feedback mechanism, this causes an increase in gastroin secretion by cells of the gastric mucosa and a compensatory increase in the secretion of hydrochloric acid and pepsin, while reducing the secretion of bicarbonates.

Mudzinase, protease and lipase produced by bacteria cause depolymerization and dissolving the protective mucus of the stomach, as a result of which hydrochloric acid and pepsin are direct access to the bare of the gastric mucous membrane and begin to destroy it, causing it chemical burn, inflammation and ulceration of the mucous membrane.

VACA endotoxin produced by the bacterium causes vacuolaization and death of the stomach epithelium cells. CAGA gene products cause degeneration of the epithelium cells of the stomach, causing changes in the cell phenotype (cells become elongated, acquiring the so-called "hummingbird phenotype"). Attracted by inflammation (in particular, the secretion of interleukin-8 cells of the gastric mucosa) leukocytes produce various inflammation mediators, which leads to the progression of inflammation and ulceration of the mucous membrane, the bacterium also causes oxidative stress and launches the mechanism of the programmable cell death of the stomach epithelium cells.

Conference with Helicobacter Pylori

Often, when Helicobacter Pylori is detected, patients begin to worry about their eradication (destruction). The very presence of Helicobacter pylori in the gastrointestinal tract is not the reason for immediate therapy with the use of antibiotics or other means. In Russia, the number of Helicobacter Pylori carriers reaches 70% of the population and the overwhelming majority of them do not suffer from any diseases of the gastrointestinal tract. The eradication procedure involves the reception of two antibiotics (for example, clarithromycin and amoxicillin).

In patients who have increased sensitivity to antibiotics are possible allergic reactions - from antibiotic-associated diarrhea (non-severe disease) to pseudomambranous colitis, the likelihood of which is small, but the percentage of lethal outcomes is large. In addition, the reception of antibiotics adversely affects the "friendly" intestinal microflora, urinary tract and contributes to the development of resistance to this type of antibiotics. It is evidence that after successful Eradication of Helicobacter Pylori over the coming years, the reinfection of the stomach mucosa is most often observed, which has already been 32 ± 11% after 3 years, after 5 years - 82-87%, and after 7 years - 90.9% ( Zimmerman Ya.S.).

While the pain was not manifested, Helicobacteriosis should not be treated. Moreover, in children under the eight years, it is not recommended to conduct eracycational therapy at all, because their immunity has not yet been formed, antibodies to Helicobacter pylori are not produced. If they have an eradication to 8 years old, then after a day, talking briefly with other children, "grab" these bacteria (P.L. Shcherbakov).

Helicobacter pylori uniquely requires eradication if the patient has a gastric ulcer or duodenal intestine, Moltoma or if he had resection of the stomach about cancer. Many authoritative gastroenterologists (not all) in this list also include atrophic gastritis. Eradication of Helicobacter Pylori can be recommended to reduce the risk of developing stomach cancer. It is known that at least 90% of incidence cancer are associated with H. pylori infection (Starostin B.D.).

Symptoms and first signs

The development of infection in the digestive tract takes a long time almost asymptomatic. The bacteria are attached to the intestinal mucosa and the 12-pans, produce a toxic enzyme, which gradually corps epithelial tissue cells.

Only when erosion and ulcers appear on the walls of the organ, the patient begins to disturb the unpleasant symptoms of Helicobacter pylori:

• the feeling of bloating and overcrowding the stomach after feeding;
• frequent belching with an actenu taste in the mouth;
• regularly hurts the stomach;
• there is a burning sensation in the esophagus, a bitter taste in the mouth;
• regular bouts of nausea, vomit urge;
• high gas formation that provokes colic and discomfort.

In adults, unpleasant signs of bacteria Helicobacter Piloras appear most often after meals and do not pass even after the intestinal emptying. The patient overcomes lethargy, decay forces, drowsiness, irritably. The presence of Helicobacter pylori in the stomach or duodenum can be accompanied by fine skin rashes, in particular, on the face. With gastritis or ulcers caused by helicobacteriosis, the patient complains about changes in the chair (constipation or diarrhea), an unpleasant smell of mouth, fragility nail plate And constant general malaise.

What diseases can provoke H. pylori

The presence of H. pylori in the stomach in itself is not a disease. However, these bacteria increase the risk of developing various diseases of the digestive tract.

Although the colonization of the gastric mucosa helicobacteri causes histological gastritis in all infected people, only a small part of them develops clinical picture of this disease. According to scientists estimates, 10-20% of people infected with helicobacter pylory develops ulcer, and in 1-2% stomach cancer.

Diseases whose development is associated with Helicobacter infection:

1. - This is the inflammation of the mucous membrane of the stomach. Shortly after infection H. pylori, a person develops acute gastritis, sometimes associated with dyspepsia or nausea. The acute inflammatory process affects the entire stomach and leads to a decrease in the secretion of acid. After a certain period of time, chronic is developing after acute gastritis.
2. and. According to scientific data, 70-85% of all the ulcers of the stomach and 90-95% of all the duodenal ulcers are caused by bacteria
3. - It is pain in the top of the abdomen, not caused by ulcers or other lesions of the stomach. The results of scientific studies have shown that some types of dyspepsia are associated with infection. Treatment aimed at the eradication of bacteria facilitates many patients with functional dyspepsiaand also reduces the risk of developing ulcers and stomach cancer in the future.
4. . Helicobacter Pilori - recognized by scientists the etiological factor in the development of gastric cancer. According to one of the hypotheses, bacteria contribute to the production of free radicals and increase the risk of mutations in the stomach cells.
5. Malt-lymphoma stomach. The relationship of infection with this disease was first reported in 1991. It is believed that this bacterium causes 92-98% Malt Lymph of the stomach.

Diagnostics

To detect infection in the body are used various methods Surveys, each of which has its advantages, disadvantages and restrictions. Traditionally, all methods are divided into non-invasive and invasive.

Invasive detection methods:

1. Histological research is the study of specially colored samples of stomach tissues obtained by biopsy during an endoscopic examination, under a microscope.
2. Microbiological sowing and isolating culture Helicobacteri. To obtain material for sowing, a biopsy is used or a sample of gastric juice, which are obtained during an endoscopic examination.
3. Polymerase chain reaction (PCR) - allows to detect an infection in small samples of tissues obtained by biopsy.
4. A quick urease test - during this method, the ability of the bacterium to the processing of urea is used. The tissue sample obtained by biopsy is placed in a medium containing urea and the pH indicator. Bacteria split urea on carbon dioxide and ammonia, which increases the pH of the medium and the color of the indicator is changed.

Non-invasive detection methods:

1. Serological blood tests, with which you can detect antibodies to helicobacteri.
2. Respiratory test with urea. During this examination, the patient is allowed to drink a solution with the urea, the molecule of which contains a labeled carbon isotope. Helicobacuti splits urea to ammonia and carbon dioxidewhich contains a labeled carbon atom. This gas penetrates the bloodstream and is excreted through the lungs with air. After half an hour after using a solution with a urea patient, he exhales into a special bag, in which a labeled carbon atom is detected using spectrometry.
3. Detection of antigens H. pylori in feces.

How to get rid of Helicobacter Pylori?

In 2019, an acceptable Eradication scheme of Helicobacter pylori in adults is considered a therapeutic regime, providing at least 80% efficiently confirmed by the re-examination of cure from helicobacter infection and healing of ulcers or gastritis, having a duration of no more than 14 days and has acceptable low toxicity (side effects need to develop Not more than 10-15% of patients and in most cases not to be so serious to require early cessation of treatment).

The new schemes and protocols of Helicobacter's eradication protocols are constantly being developed. At the same time, several goals are pursued:

• increased the ease of treatment for patients and the degree of compliance with the treatment regime: elimination of the need for a strict "anti-sized" diet
• thanks to the use of powerful proton pump inhibitors;
• reducing the duration of treatment (from 14 to 10, then 7 days);
• reduction of the number of simultaneously accepted drug names due to the use of combined drugs;
• reducing the number of techniques per day due to the use of prolonged forms of drugs or preparations with a large half-life (T1 / 2);
• reducing the probability of unwanted side Effects;
• overcoming the growing stability of the Helicobacter to antibiotics;
• satisfying the need for alternative treatment schemes in the presence of allergies to any of the components of the standard scheme or with the failure of the initial treatment regimen.

In 2019, the following eradication schemes Helicobacter pylori were recommended by Maastricht-IV experts:

Three-component therapy was proposed on the first Maastricht Conference and became a universal treatment diagram of H. pylori infection. It is recommended by all global conciliation conferences.

The scheme includes drugs:

• one of the proton pump inhibitors (IPN) in the "standard dosage" (omeprazole 20 mg, Lansoprazole 30 mg, pantoprazole 40 mg, Ezomeprazole 20 mg, or Rabeprazole 20 mg 2 times a day) at least 7 days
• clarithromycin (500 mg 2 times a day) 7 days
• amoxicillin (1000 mg 2 times a day) or metronidazole (500 mg 2 times a day) 7 days.

At the same time, it was shown that the schemes of IPN + Clarithromycin + Metronidazole (Tinidazole) and IPN + Clarithromycin + Amoxicillin are equivalent. It has been established that the effectiveness of triple therapy increases, with an increase in its duration up to 10 or 14 days (depending on the degree of Helicobacter Pylori, and the patient therapy is tolerated).

In connection with various resistance to antibiotics in different regions of the world, the prevalence of various NR strains, genetic characteristics of the population, different countries or groups of countries are developed their recommendations for the eradication of HP. Some of these parameters, in particular, the resistance of HP to certain antibiotics changes over time. The choice of a specific scheme is also determined by the individual intolerance to the patient to the drugs, as well as the sensitivity of HP strains that are infected with the patient.

At the congress of the scientific society of the Gastroenterologists of Russia, the following Eradication schemes of HP were adopted, they are relevant for 2019:

1) the first option. Threecomplete therapy, which includes the drugs listed below, which are accepted within 10-14 days:

• one of the IPNs in the "Standard Dosage" 2 times a day +
• clarithromycin (500 mg 2 times a day), or Josamamicin (1000 mg 2 times a day) or nifuratel (400 mg 2 times a day).

2) the second option. Four-component therapy, including in addition to drugs 1 Preparation of bismuth, its duration is also 10-14 days:

• amoxicillin (500 mg 4 times a day or 1000 mg 2 times a day) +
• bismuth tricia Dicitrate 120 mg 4 times a day or 240 mg 2 times.

3) the third option. If the patient has a confirmed intragastric pH-metry of atrophy of the gastric mucosa with ahlorohydria and it is thus it is inappropriate to prescribe acid-based drugs (IPN or H2-blockers), the third option is used (duration of 10-14 days):

• amoxicillin (500 mg 4 times a day or 1000 mg 2 times a day) +
• clarithromycin (500 mg 2 times a day), or josamicin (1000 mg 2 times a day), or nifuratel (400 mg 2 times a day) +

4) Fourth option. If the elderly patients are impossible for full-fledged eradication therapy, truncated schemes are used:

• one of the IPNs in the "Standard Dosage" +
• amoxicillin (500 mg 4 times a day or 1000 mg 2 times a day) +
• bismuth tricia dicyrate (120 mg 4 times a day or 240 mg 2 times a day).

Another way: bismuth tricia dicyrate 120 mg 4 times a day for 28 days. In the presence of pain in the area of \u200b\u200bthe stomach - a short rate of IPN.

Possible complications from treatment with antibiotics

Factors increasing the risk of side effects when conducting eradication therapy:

1. Individual intolerance to drugs;
2. The presence of somatic pathologies;
3. Negative state of intestinal microflora in the initial period of treatment.

Complications of Eradication Therapy - Side effects:

1. Allergic reaction to the components of drugs disappearing after the cancellation;
2. Dyspeptic phenomena of the gastrointestinal tract (discomfort in the stomach and intestines, the taste of bitterness and metal, nausea and vomiting, diarrhea, meteorism). Usually all these phenomena are spontaneously passing a short time. In rare cases (5-8%), the doctor assigns funds against vomiting or diarrhea, or cancels the course.
3. Dysbacteriosis. It is more often manifested in patients who had previously had a violation of the GTS function, it develops in the treatment of tetracycline drugs or with macrolide therapy. A short course is not able to disrupt the intestinal microflora balance, for the prevention of dysbacteriosis, it is necessary to use ferocular products more often: yogurt, kefir.

Food and diet

Of course, the main point in the treatment of this pathology is the reception of medical drugs, but the proper nutrition plays an equally important role. To easily get rid of cheilicobacteriosis, the following recommendations should be followed:

• do not make large intervals between meals;
• eat in small portions;
• observe 5-6 one-time power regimen, it is necessary to slowly, fiercing food well and drinking it with a sufficient amount of liquid;
• the patient should abandon the too fat, fried or acute food, carbonated drinks, pickled dishes, alcohol.

Prevention

Fully cure from cheilicobacteriosis, if in addition to therapy adhere to preventive measures:

1. Compliance with hygiene. Wash your hands before applying food, do not use dirty vegetables and fruits, dubious water. Do not use other health items.
2. Timely detection of the disease. With poor well-being or suspicion of the presence in the body of pathogenic bacteria, it is important to immediately turn to the doctor, go through the necessary tests.
3. Strengthening immunity. Healthy image Life (swimming, running, hiking) increases protective forces and prevents the penetration of pathogens into the body.
4. Proper nutrition. Food fraction, small doses and refusal of fried, salty, sharp, smoked, alcohol and smoking.

The main danger of Helicobacter pylori is that it can provoke gastritis, an ulcer even a tumor of malignant character. From malicious bacteria it is impossible to get rid of antibiotics. Therefore, it is important to strictly adhere to special treatment schemes and comply with preventive measures.

What doctor treatshelobacteriosis?

With the appearance of pain and other negative symptoms in the stomach, as well as in the diagnosis of bacteria, you need to contact a gastroenterologist. If similar problems appeared in children, you should consult with a children's gastroenterologist.

In the absence of these specialists, you need to turn to the therapist, in the treatment of children - to the pediatrician.

You are worried out of heartburn, abdominal pain, nausea, belching, fast saturation after meals? It may turn out that the main reason for such complaints is an infection that causes bacterium Helicobacter Pilori is the main pathogen, the main culprit of chronic gastritis of the stomach and ulcers.

What is Helicobacter and Helicobacter infection that binds it with diseases of the gastrointestinal tract? What to do to find out whether you are threatened with Helicobacter pylori, diagnostics, analysis on Helicobacter Piluri, symptoms of helicobacteriosis, what are they? How not to get sick, do not catch this infection? And, of course, how to treat Helicobacter Pilori, medicines from this ailment? All this, in our article.

What is Helicobacter Pilori and what is it terrible?

The chain reaction that the Helicobacter bacterium can run, looks truly threatening:

Infection Helicobacter Pilari \u003d\u003e Inflammation (gastritis, ulcer, etc.) \u003d\u003e Atrophy \u003d\u003e Metaplasia \u003d\u003e Cancer

So what is Helicobacter and who should be afraid of it?

Helicobacter Pilori is just a bacterium, which is found in patients with various diseases of the stomach and intestines, duodenum in particular.

As for the title of the bacterium, Helicobacter Pylori (Helicobacter Pylori), then it is not at all by chance. One part of it, "Pylory," indicates the main habitat of the bacterium - the pyloric department of the stomach, and the second part, "Helico", characterizes the shape of the bacteria: a screw-like, spiral-shaped.

Earlier in medicine it was believed that a microorganism capable of surviving in an acidic, hydrochloride of the stomach in principle does not exist. But then doctors did not suspect the existence of helicobacteria. Helicobacter Pilori was opened only in 1979 by scientists from Australia Robin Warren. Together with the scientist with a colleague, Dr. Barry Marshall "discoveries" managed to grow this bacterium Helicobacter in laboratory conditions. Then they only suggested that it was she who was the guilt of gastritis and a stomach ulcers, and not at all the wrong food or stress, as previously thought.

In an attempt to confirm the rightness of his guess, Barry Marshall conducted an experiment on himself, drinking the contents of Petri dishes, in which Helicobacter Pilori was cultivated. After literally a few days the scientist showed gastritis. It was able to cure it, taking the Metronidazole over two weeks. And already in 2005, the authors of this discovery scientists for their discovery were received by the Nobel Prize in Medicine. The whole world acknowledged that ulcers and gastritis, with all the resulting and related diseases, appear precisely because of helicobacteria.

Where do cheelicobacteria come from?

Helicobacter adapted and survives in human organism. This bacterium has flagellas, thanks to which it quickly moves in a thick mucus, which lins the walls of the stomach. Moreover, it produces ureazu - a special enzyme, neutralizing hydrochloric acid and providing a comfortable environment for bacteria. The occurrence of gastritis occurs due to the separation of the bacterium toxins, first, and secondly, dissolving the protective mucus, as a result of which the food enzymes and hydrochloric acid fall on the gastric mucosa, energized to the ulcers.

Helicobacter, as it turns out, is a very common infection. Scientists believe that its carriers are 2/3 of the population of the entire planet. Less than all people are infected with Helicobacter infection in the United States and Western Europe. This is explained with the fact that antibiotics are most widely used in there, in combination with compliance with high standards of sanitation and hygiene.

Opening of the bacterium Helicobacter Pillori became truly revolutionary, because, together with him, the myth was dispelled that bacteria could not survive in an acidic gastric medium, and it turned out that it was this bacterium that causes most of the well-known gastric diseases. In addition, since it is bacteria, it means to prevent and cure ulcers, gastritis and other diseases of the stomach and intestines can antibiotics in the reducing therapy.

Features Helicobacteria

First feature:bacteria successfully opposes an extremely acidic gastric medium. Due to the high acidity, bacteria and viruses in the stomach are dying, in any case, their majority. Helicobacteria resist acidity using two mechanisms:

• 1. Since its ingress in the stomach, it, using its flagella, moves and is hidden in the mucus covering the wall of the stomach and protecting the cell of the mucous membrane from the acid medium - that is, in a safe place.
• 2. In addition, the bacteria increases the protective secretion of ammonia, which neutralizes, the acidic stomach environment around it.

Thus, the Helicobacter bacterium is fixed on the walls of the stomach and is able to stay there, for many decades in complete "comfort and safety".

Second feature:bacteria is the main cause of diseases arising in the stomach and duodenalist. Spinning, bacterium just destroys the stomach cells. Namely, chronic inflammation and gastritis makes the release of bacteria harmful substances, toxins.

As a result of the weakening of the gastric mucosa, the duodenum appear erosion and ulcers, and the risk of developing the gastric cancer increases. It is already known that the bacterium Helicobacter is the main cause of the gastric cancer in humans.

Third feature:helicobacter infection is destroyed by the treatment of Helicobacteriosis with antibiotics and drugsregulating the level of acidity in the stomach.

Causes of Helicobacteriosis

On the air bacteria Helicobacter Pylory can not live, they die. Helicobacter infection is transmitted only through saliva and mucus at the contact of the bacterium carrier and healthy man. Often infection occurs as a result general use Personal hygiene, dishes, with a kiss or from mom to child. That is, family, cohabitants or friends of a person, who is a carrier Helicobacter Pilori fall into the infection risk group.

Finding into the stomach through a person's esophagus, the bacterium does not die under the influence of hydrochloric acid. Further, everything is already a well-known scheme: Bacteria lives, multiplies, helicobacteriosis develops, poisoning the body, destroys the tissues of the stomach and intestines, violates normal functioning. Further, inflammation of the gastric mucosa, the development of gastritis, ulcers, the risk of cancer of the stomach and other no less dangerous diseases.

Helicobacter Pilari: Helicobacteriosis symptoms

Helicobacter Pilori, symptoms indicating possible infection, has frequently repeated pain in the stomach. As a rule, the pain comes on an empty stomach, and calms down after meals. This testifies to the presence of erosion and ulcers on the walls of the stomach, which were formed as a result of the vital activity of the bacteria.

Also, symptoms of helicobacteriosis can manifest itself in the form of heartburn, increasing over time, gravity in the stomach, poor digestibility of meat food, nausea and vomiting.

If a person has specified symptoms of helicobacteriosis, it should be passed the test - an analysis of the chilicobacter pylori, the diagnosis implies the use of biochemical reactions in serum, according to which the content of immunoglobulins determine. Also for diagnostics use breathing test and endoscopy.

Helicobacter Pilari: Diagnostics

Mandatory to determine the bacterium tests are histological and urease analysis on Helicobacter Pilori. There are others.

• Cytological examination.

By making this analysis on Helicobacter Pilori, the prints-prints obtained during endoscopy (1-2 and more smears) from the biopsy of the mucous membrane of the anthral stomach department are used. Take a bioptat sight from the plots where visual deviations from the norm (swelling, hyperemia) are most pronounced, but not from the bottom of erosion and ulcers. Then the smears are dried and painted.

As a rule, helicobacteria is located in mucus, they have a spiral, curved, or S-shaped, can also be like "Wings of a flying seagull".

As for the question, what helicobacter Pilori is a norm, the answer is obvious: ideally therefore be unlomstically, but a small number of microbial bodies does not carry a special threat, in any case, until their amount has grown. The cytological study allocates three degrees of the exchanging bacteriums of the gastric mucosa: (+) - up to 20 microbial bodies - this is a weak dishoneser, (++) - up to 40 - the average dissemination, and the high disgrace - (+++) - in view of more than 40 microbial bodies with increasing x360.

In the case of detection in cheelicobacteriosis brinks, cell infiltration is also detected, characterized by the presence of plasma cells, lymphocytes, eosinophilia and neutrophilia.

On the prevalence of certain cell elements, indirectly judges the degree of activity and severity inflammatory process. In addition, the cytological study allows the proliferative processes and the degree of their severity, dysplasia and its severity in the cells of the mucosa, duodenuum and intestinal in the stomach) in the cells of the mucous membrane. However, the cytological method does not allow to learn about the structure of the mucous membrane under study.

• Urease test.

Urease express method is based on uretic activity of helicobacteria. Tests are made using a carrier gel that contains a bacteriostatic agent, urea, and phenol-roll, as the pH indicator. The indicator allows you to draw conclusions about the condition of the mucous membrane, changing the color of the contents of the analysis on the Helicobacter pylori from yellow to the raspberry. Obtained with endoscopy, bioptat mucosa, placed in the test, and evaluate the result.

Rasian dough staining that comes after this immediately indicates the presence of a bacterium Helicobacter. The change in the color of the study environment takes place only if in a bioptate, which is taken to the analysis on the Helicobacter pylori, there is urease, allocated by the bacterium. The color change time speaks of the number of viable bacteria. If raspberry staining appears in the first hour, the study, this says that the mucous membrane is significantly infected (+++). If the painting occurred during the two subsequent hours - this indicates a moderate infection (++). Unless by the end of the day - then the infection is insignificant (+). When the staining occurs on time later, the result is considered negative, no Helicobacter pylori is normal.

It happens that the test can give false-negative results, especially if the Helicobacter infection is weak. To increase the accuracy of the diagnosis of helicobacteriosis, it is recommended to combine both analyzes on Helicobacter pylori, and histological and urease methods. In particular, it is important to conduct them no earlier than they will expire for four weeks after antibacterial treatment Ends, because it may be necessary to conduct a repeated course of combined antigelicobacter therapy, in order to avoid unsuccessful treatment and emergency recurrence.

• 13C urease test, respiratory.

This method is non-invasive, is considered absolutely safe, and allowing to determine the degree of colonization, the population of the stomach mucosa of these bacteria. The respiratory analysis of the chilicobacter pylori is optimal in order to control the eradication therapy.

Performing an empty stomach for a start, take samples of exhaled air, so-called background. After the study takes an easy test breakfast (juice, milk, etc.) and with it a test substrate (urea solution, labeled 13C). Then for an hour with an interval of 15 minutes, four "final" samples of exhaled air are taken.

The result of the test is determined by the content of stabilized isotop in the exhaled air, with the help of a mass spectrometer. 4 degrees of infection of the gastric mucosa with a given bacterium are distinguished: light - with a stabilized isotope content is less than 3.5%, middle degree - 3.5-6.4%, a severe degree - 6.5-9.4%, and the degree is extremely severe - when the stabilized isotope is more than 9.5%. The stabilized isotope 13C is normal there is no more than 1% of the total amount in the exhaled air C02. That is, Helicobacter pylori norm is 1% at 13c ureaznny respiratory test.

• Histological methods

Histological research allows you to quickly detect Helicobacteria in biopsy, while having studied the morphological changes and their presence in the mucous membrane. The simplest and affordable is the coloring method for gymse without differentiation. At the same time, the available helicobacteria is painted in a dark blue color, they are very clearly visible in the depths of the pits, and on the surface of the epithelium. To assess the condition of the mucous membrane and detect a helicobacter infection of enough two biopsy.

In addition, there is also a histological method of DNA hybridization, for which ordinary paraffin sections are needed. The technique is very sensitive, and highly specific, which allows you to identify different strains Helicobacter pylori. In addition, the method allows you to understand nature, in cases of re-detecting bacteria after successful treatment - To understand whether it is a helicobacter infection or reproduction, older preserved as a result of the treatment of bacteria.

Helicobacter Pilari: Diagnostics with additional methods

In addition to the described methods, there are also other research methods, in particular: microbiological, immunological, determination of antigen in feces, polymerase chain reaction, and others modern methods. The analysis on the Helicobacter Pilori takes not only the results of endoscopy, but they explore blood, breathing, cal.

Helicobacter Pilori: Hheebacteriosis treatment

Treatment from Helicobacter Pilori provides for comprehensive therapyaimed at the destruction of malicious microorganism Helicobacteria in the stomach. Helicobacteriosis treatment by destroying bacteria is a prerequisite for the healing of erosions and ulcers begins. Prevent and cure ulcers, gastritis and other diseases of the stomach and intestines, associated with the vital activity of bacteria can antibiotics in the composition of regenerating therapy.

Helicobacteriosis treatment is carried out by antibiotics and drugs regulating the level of acidity in the stomach.

It should be known that not all carriers of this bacterium are experiencing symptoms of the disease. Bacterry may not be able to show itself very long time, while persisting in an inactive state in the walls of the stomach. For development, the intensification of helicobacteriosis is largely affected by the lifestyle, which leads a person: improper nutrition, abuse of alcohol, smoking and frequent nervous overvoltages, weakening the protective functions of the body.

Therefore, the prevention of infection with Helicobacter is particularly important. Observe the elementary rules of hygiene: Wash before eating hands, do not use the common and dirty dishes, other personal hygiene. In case of detection of human helicobacteriosis, all members of his family are subject to a survey, without exception.

• 1. ulcerative duel disease and stomach, and as in the period of exacerbation of the disease, so when remission (open, closed, bored, after stopping bleeding, complicated flow, after a surgery in view of the complications of the disease, according to the anamnesis);
• 2. Atrophic gastritis;
• 3. Maltoma stomach;
• 4. resection of the stomach due to cancer;
• 5. Direct relationship with a person sick cancer of the stomach.

Treatment Scheme Helicobacter Pilora

Any treatment schemes of helicobacter infection must necessarily include at least 3 drugs - two antibiotics (usually amoxicillin and clarithromycin) and the proton pump inhibitor (usually pariet) is the so-called triple eradication schemes.

• Remember: if you, by mistakes or negligence, is scheduled for some kind of double treatment scheme Helicobacter Pilori - it is ineffective! Only a triple eradication scheme can help.

Helicobacter Pilari: Medicines for treatment schemes

We list the most effective treatment schemes Helicobacter Pilori, drugs used for this in our country:

• 1. Triple eradication scheme with a duration of 7 days, includes drugs: Pariet + amoxicillin + clarithromycin.
• 2. Quadrotherapy duration 7 days (four-component treatment diagram Helicobacter pylori): Pares + metrolazol + tetracycline (clarithromycin can be prescribed instead of tetracycline) + bismuth salts preparations.
• 3. The most effective, high-speed antisecretory and antibacterial drugWhen conducting comprehensive treatment From Helicobacter Pilora - Pariots, they are prescribed twice a day at a dose of 20 mg. It does not need to be appointed a week before the start of taking antibiotics, as necessary when applying other proton pump inhibitors, since already in the first day of treatment there comes a reliable antisectory effect.
• 4. Purpose as antisecretory drugs H2-blockers reduces the effectiveness of the treatment schemes of Helicobacteriosis.
• 5. Includes in the triple schemes of eradication metronidazole, since in our latitudes and microclimate (Russia, Ukraine), the primary stability (resistance) of this bacterium to the metronidazole, which reaches 45% is very high. For example, the treatment diagram Helicobacter Pilari: a proton pump inhibitor + amoxicillin + metronidazole - in principle is unacceptable.
• 6. Metronidazole can be included only in the Quadrapepian schemes.

In addition, it is important to know that the doctor cannot replace medications and reduce the dose of drugs specified in the doses of drugs at their discretion, as this may significantly affect the efficiency of the entire course of treatment, and the appearance of remissions.

A little more about Helicobacter Pilora, Helicobacteriosis treatment: