Glucose - instructions for use. Dropper with glucose: for what is needed and how the body of glucose injections is helped for what

06.08.2020 Glucometers

Glucose is produced in the form of isotonic solution, as well as in the form of hypertensive. The first is needed in order to restore the work of our organs and to enrich the body fluid. The second is necessary for improving metabolism and liver work, increasing diuresis, extensions of vessels, etc. Assign it in the form of injections, intravenously, less frequently intramuscularly. It also drip it in combination with other medicines, and some people (athletes, for example) prefer to drink it.

Who needs glucose: testimony, contraindications

Indications for the use of dextrose solution (so differently this drug is called) are quite varied.

Glucose in the form of injections or droppers is prescribed with such problems as:

  • Reducing blood sugar levels (it is hypoglycemia);
  • Infections;
  • Reducing pumping functions of the heart;
  • Liver dystrophy and other diseases;
  • Physical exhaustion;
  • Alcohol poisoning and other poisons;
  • Hepatitis;
  • Lung swelling;
  • Hemorrhagic diathesis;
  • Prostration;
  • Blood loss;
  • Drop pressure;
  • some other testimony

Also, a dropper with glucose is prescribed if you need to enter heart glycosides or other medicines or dehydration.

Glucose is contraindicated in diabetes mellitus and hyperglycemia, as well as hypershydration, hypersmolar coma and hyperlactacidemia. In the heart failure and mouth of Anuria, a solution of glucose with caution can be used.

Dropper

Isotonic solution is administered subcutaneously from 300 to 500ml. It is also possible to introduce into ephtles or drip (intravenous). In this case, the patient must receive about 2 liters per day. Solid. A five percent isotonic dextrose solution is injected with a dropper into a vein or under the skin, or a rectum with strong blood loss, dehydration or shock. In this case, you need to enter from 300-400 ml to the liter-two in 24 hours. If the solution is five percent, fits the velocity of up to 7 ml. per minute, if a decade percent, speed should be equal to three milliliters per minute.

Other ways of administration

Isotonic solution in pure form is administered intravenously in combination with a solution of ascorbic acid. The volume of the solution is 30-50 ml. The solution of methylene blue single interest is introduced by the victims of the sinyl acid suffered after the poisoning. It is not recommended intramuscularly glucose, since inflammation of subcutaneous fiber and purulent foci may occur. Intravenous injections have the same testimony as droppers, but they are prescribed if the slow and gradual glucose administration is not required and no additional preparations are required. The injection in the vein glucose is no different from other intravenous injections. In order for it to be successful, you need to find a "working venu" on the hand and everything is good to disinfect.

Glucose is the main source of energy in cellular metabolism, as well as a supplier of carbohydrates in parenteral nutrition with light digestibility. It contributes to an increase in the energy potential of the body and stimulates its basic functions. So glucose-dropper: what is it used for?

When a glucose solution for infusion is prescribed?

As a rule, for infusion, that is, an intravenous administration with a dropper, a 5% glucose solution is used, packaged in hermetic polyethylene packages with a volume of 400 ml or bottles. The solution consists of an active substance, glucose and water for injection.

In the intravenous administration of glucose is metabolized by acids, decaying on carbon dioxide And water, while highlighting energy. Subsequent pharmacodynamics is determined by the nature of the tool used, which is diluted with glucose.

The dropper with glucose is shown in the treatment of diseases such as:

  • shock state;
  • bleeding;
  • increased bleeding;
  • diarrhea and vomiting;
  • critical reduction in blood sugar levels in hypoglycemia;
  • acute heart failure;
  • a sharp decrease in blood pressure characteristic of the state of the collapse;
  • cluster in light liquid;
  • liver disease;
  • infectious diseases;
  • dehydration and carbohydrate exhaustion when the usual food and fluid consumption is limited;
  • as a carrier and diluent of other combined medical staff.

Contraindications and precautions

Infusion with glucose solution is contraindicated to people with such pathologies:

  • decompensated diabetes;
  • intolerance to glucose, for example, in the case of metabolism of stress situations;
  • with hyperosmolar coma;
  • in the case of hyperglycemia and hyperlactaramia.

Cautions for use:

  • Large volumes of infusion of the solution must be carried out under a special observation of patients with water intoxication, heart failure, the presence of fluid in the lungs or swelling.
  • Due to the risk of the occurrence of hyperglycemia, it is necessary to intimidate a solution to patients undergoing ischemic stroke.
  • In the cranial injuries, the infusion solution should be used during the first day, carefully controlling the glucose concentration in plasma.
  • Glucose should not be dripping at the same time, after and immediately before the blood transfusion into the same vein, which can provoke hemolysis and non-specific agglutination.
  • Intravenous administration of glucose solutions to infants, especially prematurely or small-weight kids, involves careful control over the length of treatment, since this category of patients has a significant risk of hyper-or hypoglycemia.

Dosage

Duration of administration intravenous solution glucose and its dosage is prescribed with several factors such as the age of the patient, weight, general state and clinical picture. This may require careful monitoring of blood glucose levels.

See also:

To treat dehydration and carbohydrate depletion, this dosage is recommended:

  • For adults: 0.5 - 3 l / 24 hours.
  • For children, including newborns, the dosage is calculated on a kilogram of the child's weight:
  • body weight up to 10 kg - 100 ml per kilogram of weight during the day;
  • mass from 10 to 20 kg - 1 l / kg / 24 hours;
  • more than 20 kg - 1.5 l / kg / 24 hours.

To avoid the development of hyperglycemia, the rate of injection of the solution is regulated depending on clinical picture. Maximum infusion speed:

  • for adults - from 5 mg per kilogram weight per minute;
  • for children, including babies - 10 - 18 mg / kg / min.

If glucose is used for transportation and dilution, the recommended dosage is in the range of 50 to 250 ml for one dose of the drug.

How to apply?

The introduction of glucose is carried out intravenously with a dropper. When using the solution in order to dilute and introduce additional therapeutic agents, infusion is carried out according to the instructions for the use of these drugs. For infusion, sterile equipment must be sealed to avoid access to the air system.

Polyethylene packages should not be used for a serial connection, which carries the risk of supplying air residue in the first prior to the end of the solution coming from the following, as an air embolion may occur. Pressing on flexible polyethylene packages for intravenous infusion in order to increase its speed can also cause an air embolism if the residual air from the container was not completely removed before administration of the solution.

Additional drugs into the solution can be introduced both before and during the infusion. A solution containing a drug adding must be immediately used because it cannot be stored.

Actions side character

Body reaction

Name of side effect

How often meet

The immune system

  • Anaphylactic reaction

very rarely

  • Allergy
  • Super sensitivity

Metabolism

  • Electrolyte imbalance

very rarely

  • Hypoglycemia
  • Gipicomagnia
  • Hipophosphamia
  • Hyperglycemia
  • Dehydration
  • Hypervolemia
  • Thrombophlebit
  • Phlebitis

very rarely

urinary system

  • Polyuria

very rarely

General disorders

  • Chills
  • Hypertermia
  • Irritation at the place of infusion
  • Hemorrhage
  • Local pain

very rarely

Dropper with glucose solution is often used during pregnancy for hydration and as a means of transporting other drugs. At the moment there is no evidence of the adverse effects of the means on the kid using a 5% solution during pregnancy, childbirth and breastfeeding.

Content

To replenish the energy by the body, nutrition of fabrics and organs, it is necessary to enter fats, carbohydrates, proteins, trace elements, vitamins. The main energy component is carbohydrates, including natural glucose, galactose, raffinosis, starch. Often, at elevated loads, glucose is prescribed in tablets, it can be used as a disinfectant, but there are contraindications to the medicine - brain swelling, diabetes mellitus.

Glucose tablets

The carbohydrate is a colorless well-soluble crystalline powder odorless with a sweet taste. Glucose is sold in a pharmacy in the form of tablets, powder for receiving inside. For parenteral use, solutions with a concentration of active component 5, 10, 20, 40% in glass or plastic containers of 200, 250, 400, 500, 1000 ml, which is used for infusion (using droppers), or in ampoules of 5, 10, 20 ml - for intravenous administration.

Composition and form of release

Tablets have a sweet taste, white color, rounded shape, a flat surface with beveled edges and a separation strip. Active substance is a monohydrate dextrose. The composition of glucose and other components in one tablet is presented in the table:

pharmachologic effect

Glucose (dextrose) refers to monosaccharides. She meets in the juice of grapes and other berries, so it received an additional name - grape sugar. From glucose links consist of disaccharides (maltose, lactose, sucrose) and oligosaccharides (cellulose, starch, glycogen). In the digestive tract, complex saccharides disintegrate to glucose and fructose. As a monosaccharide substance is present in the blood, lymph, brain, skeletal muscles and myocardium.

The glycogen deposited in the body also serves as a source of energy - it is cleaved by dextrose if necessary. Regulation of the balance of monosaccharide and oligosaccharide is carried out with the help of enzymes. Reduces the level of glucose in the blood of insulin, and its antagonists increase the concentration of sugar: glucagon, adrenaline, thyroxine, triiodothyronine. In violation of the activities of the endocrine or central nervous system An excessive increase in sugar levels can occur and hyperglycemia or a sharp drop in its concentration - hypoglycemia.

Dextrose participates in carbohydrate exchange and has an impact on metabolic processes:

  1. Glucose in the body is necessary for the full splitting of fats, fatty acids accumulate during the deficit (acidosis, ketosis) accumulate.
  2. In the process of glucose metabolism, adenosyntrifosphoric acid is formed, which is the source of the body's energy.
  3. Hypertensive solution of dextrose is capable of: "squeeze" liquid into the bloodstream from organs and tissues, and with it toxins and remove from the body; increase the amount of urine; strengthen the activities of the heart muscle; Expand vessels.
  4. Isotonic solution can fill the loss of fluid.
  5. The substance is used for carbohydrate nutrition of the brain and muscles - the absorption of glucose occurs quickly, the mental and physical performance increases.

What is useful glucose

The properties of the substance have a positive effect on exchange processes Used in the treatment of ailments. Pregnant women are prescribed reception of dextrose with suspicion of the small size of the fetus, as well as to reduce the risk of miscarriage and premature birth. It helps in this period to overcome fatigue and improve well-being when sugar level falls and tremble hands. During pregnancy and lactation during the use of the drug, it is necessary to constantly monitor the level of sugar. According to the instructions, the drug is prescribed:

  • with a shortage of carbohydrates, in hypoglycemia;
  • with intoxication due to liver disease (with hepatitis);
  • for the treatment of poisoning;
  • when decompensing cardiac activity;
  • to replenish the fluid after the operation, in diarrhea or vomiting;
  • with shock, collapse (sharp drop in pressure).

How to drink glucose

Apply glucose in tablets should be inside sublingual - the method of resorption under the tongue. Drinking should be used in an hour or one and a half before eating, because the use of dextrose reduces appetite. The dosage depends on the age, weight and state of the patient. It is impossible to independently assign the drug, since there are a number of contraindications for receiving.

With poisoning

The preparation is used as a disinfectant. During the treatment of poisoning with silic acid, arsenic, carbon monoxide, aniline, paracetamol, along with other drugs, glucose is prescribed to the patient to improve the patient's condition. The drug is effective for body intoxication due to the violation of the liver function. Patients are recommended to take 2-3 tablets with an interval of 2 hours before the status improvement.

With diabetes

Due to the strong emotional overvoltage or the adoption of a large dose of insulin, in case of non-compliance with the necessary gaps between meals during diabetes mellitus, a sharp decrease in sugar levels may occur. To normalize it requires reception of chewing tablets. With severe hypoglycemia, 1-2 pieces should be taken after 5 minutes before eliminating weakness, sweating, trembling.

With more lung conditions, they use 3-4 tablets after 30 minutes. Reception declarations stop after disappearance characteristic signs. It is important not to confuse the symptoms of hypoglycemia with features characteristic of hyperglycemia and control the concentration of sugar using instruments. Otherwise, a sharp increase in its level will occur, the patient's condition will deteriorate and can come shock.

Glucose for athletes

Receiving tablets athletes are prescribed during elevated physical Loads - With intense training. Dextrose needed muscles of athletes to quickly replenish the energy supply of the body. Take the drug before training is not worth it, because there will be an increase in the level of insulin, and then the sharp drop in the concentration of sugar. It is better to use the drug 1, -2 hours to physical exertion. For reception, 7 tablets should be dissolved in 1 gram in a liter of water and drink 4 cup of liquid with a minute interval.

Glucose Children

Often, pills are prescribed together with the taking of ascorbic acid. With this combination of drugs, synthesis of corticosteroids is enhanced, so you need to monitor the kidney function, arterial pressure, Insulin level. The daily rate for a child over 6 years old is no more than 500 mg of dextrose. This dose can be divided into 3-5 receptions. In children with large energy consumption of the body, there is a sharp decrease in the level of sugar, so fat is beginning to split fat, and the formation of acetone occurs.

Such states may be accompanied by vomiting. When acetone appears, the child gives several tablets at once and abundant drinking. Children under 3 years old glucose are not prescribed - they need to give ready-made 5% solutions or dissolve the preparation in water. Do not eat baby sweet fluid before feeding, because they can refuse milk.

Side effects

The instruction contains warnings about the possibility of the offensive side Effects After receiving dextrose. The use of the drug causes an increase in cholesterol levels, which can lead to the formation of thromboms and inflammation of the veins - thrombophlebitis. Rarely after receiving tablets may be observed:

  • decline in appetite;
  • hypervolemia;
  • left-deceiving deficiency;
  • nausea, feeling thirst, dyspepsia, meteorism.

Overdose

If the recommended norms are exceeded side effects observed more often. With simultaneous reception of excessive doses of dextrose with ascorbic acid, headaches may occur, elevated excitability, Damage to mucous gastrointestinal tract, bloating, rarely - insomnia. When overdosing the drug, it is possible: decrease in insulin synthesis, the offensive of hyperglycemia; Reduced appetite. With such states, the reception of dextrose should be discontinued and consult a doctor to appoint symptomatic treatment.

Contraindications

The instruction contains information on existing contraindications to the drug reception. It is impossible to use glucose when:

  • individual intolerance to the components contained;
  • hyperglycemia;
  • diabetes;
  • high level lactic acid;
  • edema of the brain or lungs;
  • violation of glucose disposal after surgery;
  • acute left left heart failure.

Terms for sale and storage

Pills in a contour or inflexible blister of 10 pieces. Contour blisters can be placed in cardboard boxes 1, 2, 5 plates in the package. The consumer in pharmacies tablets are released without a recipe. You can store the medicine without access of solar illumination at temperatures below 25 degrees no longer than 4 years from the release date.

Analogs

In pharmacies, you can purchase analogs of tablet glucose. Their active component is a monohydrate dextrose, so drugs have similar properties. These funds include:

  • Glucose ini;
  • Glucose brown;
  • Glucose-Wiel;
  • Glucose e;
  • Glucosteril;
  • Dextrose;
  • Dextrose monohydrate;
  • Dextrose-Wiel;
  • Likadex PF dextrose monohydrate.

Dosage form: & nbspsolution for infusion Structure:

Per 1 ml:

Active component:

Dextrose (glucose) monohydratein terms of dextrose

0.05; 0.1; 0.2; 0.4 g

Excipients:

Sodium chloride

0.00026

0.1 M hydrochloric acid solution

To pH 3.0-4,1

Water for injections

Up to 1 ml

Theoretical Osmolarity

277; 555; 1110; 2220 mosm / l

Description: 5% and 10% solutions: transparent, colorless liquid.

20% and 40% solutions: Transparent, from colorless to light yellow liquid.

Pharmacotherapeutic Group:Power of carbohydrate ATH: & NBSP
  • Carbohydrates
  • Pharmacodynamics:

    Glucose enhances the redox processes in the body, improves the antitoxic function of the liver, enhances the contractile activity of myocardium, is the source of easily durable carbohydrates.

    Pharmacodynamic properties 5%, 10%, 20% and 40% dextrose solutions are similar to glucose properties - the main source of cell metabolic energy.

    5% dextrose solution It is an isotopic solution with osmolarity of about 277 mosm / l. The caloric consumption of a 5% dextrose solution is 200 kcal / l.

    10% dextrose solution It is a hypertensive solution with osmolarity of about 555 mosm / l. Caloric content 10% declaration solution is 400 kcal / l.

    20% Dextrose Solution It is a hypertensive solution with osmolarity of about 1110 mosm / l. The calorie consumed of a 20% declaration solution is 680 kcal / l.

    40% dextrose solution It is a hypertensive solution with osmolarity of about 2220 mosm / l. Calorile content of 40% declaration solution is 1360 kcal / l.

    Within parenteral nutrition 5%, 10%, 20% and 40% dextrose solutions are administered as a carbohydrate source (separately or as part of parenteral power if necessary).

    5% and 10% dextrose solutionsallow you to replenish the lack of fluid without the simultaneous administration of ions.

    20% Dextrose Solution Provides maximum calorie volume in a minimum volume of fluid.

    40% dextrose solution It makes it possible to restore the blood glucose concentration in hypoglycemia with the introduction of the minimum amount of fluid, increases the osmotic blood pressure, increases diuresis.

    Dextrose, entering the tissue, phosphorylated, turning into glucose-6-phosphate, which is actively involved in many links of the organism.

    When applying dextrose solutions for breeding and dissolving administered parenterally medicinal preparationsThe pharmacodynamic properties of the solution will depend on the added substance.

    Pharmacokinetics:

    Glucose is metabolized by two different ways: anaerobic and aerobic.

    Dextrose, decaying on peer-grade or milk acid (anaerobic glycoliz), metabolized to carbon dioxide and water released.

    When applying a declaration solution for dilution and dissolving administered parenteral drugs, the pharmacokinetic properties of the solution will depend on the substance added.

    Indications:

    5% glucose solution:

    For breeding and dissolving administered parenteral drugs.

    10% Glucose solution:

    As a source of carbohydrates (separately or as part of parenteral nutrition, if necessary);

    For rehydration in case of fluid loss, especially in patients with a high need for carbohydrates;

    For breeding and dissolving administered parenteral drugs;

    For the prevention and treatment of hypoglycemia.

    20% and 40% glucose solutions:

    As a source of carbohydrates (separately or as part of parenteral nutrition, if necessary), especially in cases of the need to limit fluid consumption;

    Hypoglycemia.

    Contraindications:

    Isotonic glucose solution 5%:

    decompensated diabetes; Other famous forms of glucose intolerance (for example, metabolic stress); Hyperosmolar Coma; hyperglycemia and hyperlactatemia; Introduction of the solution for the first 24 hours after the injury of the head; increased sensitivity to the components of the drug; application in patients with well-known corn intolerance or corn products (upon receipt of dextrose from corn); Contraindications to any drugs added to glucose solution.

    Hypertensional glucose solution 10%:

    decompensated diabetes mellitus and nonachar diabetes; Other famous forms of glucose intolerance (for example, metabolic stress); Hyperosmolar Coma; hyperglycemia, hyperlactatemia; Hemodilution and extracellular hyper hydration or hypervolemia; Heavy renal failure (with Oligira or Anuria); decompensated heart failure; generalized swelling (including pulmonary edema) and liver cirrhosis with ascites; Introduction of the solution for the first 24 hours after the injury of the head; increased sensitivity to the components of the drug; application in patients with well-known corn intolerance or corn products (upon receipt of dextrose from corn); Contraindications to any drugs added to glucose solution.

    Hypertensive solutions of glucose 20% and 40% (optional):

    intracranial hemorrhage and hemorrhage in spinal cord, childhood (For solutions above 20%).

    Carefully:

    Diabetes, intracranial hypertension, hyponatremia, children's age.

    Pregnancy and lactation:

    Dextrose solution 5%during pregnancy, it is commonly used as a hydrating and vehicle When using other drugs (in particular oxytocin).

    Dextrose solution 5% and 10%you can safely apply during pregnancy and in the period breastfeeding provided that electrolyte balance And the balance of fluids is controlled and are within the physiological norm. If the manufacturer is injected with glucose intravenously, then the concentration of glucose in its blood should not exceed 11 mmol / l.

    Feeding during infusion is trying not to interrupt.

    Purpose 20% and 40% dextrose solutions During pregnancy and breastfeeding, it is possible only for the purpose and under the control of the doctor if the intended benefit for the mother exceeds the potential risk to the fetus or infant.

    If the dextrose solution is added to the drug, the properties of the drug and its use during pregnancy and during breastfeeding period are considered separately.

    Method of use and dose:

    Intravenously (drip). The drug is usually injected into peripheral or central Vienna.

    The concentration and dose of the injected solution depend on the age, body weight and the clinical state of the patient.

    The use of the drug should be carried out under regular medical supervision. Clinical and biological parameters should be carefully monitored, in particular, the concentration of glucose in the blood, as well as the water and electrolyte balance.

    In adults with normal metabolism daily dose The glucose administered should not exceed 4-6 g / kg, i.e. About 250-450 g (with a decrease in the intensity of metabolism, the daily dose is reduced to 200-300 g), while the daily volume of the injected fluid is 30-40 ml / kg.

    Children For parenteral nutrition, along with fats and amino acids, 6 g of glucose / kg / day are introduced on the first day, subsequently - up to 15 g / kg / day.

    Introduction speed: At the normal state of metabolism, the maximum rate of administration by adults is 0.25-0.5 g / kg / h (with a decrease in the intensity of metabolism, the rate of administration is reduced to 0.125-0.25 g / kg / h). In children, the rate of glucose administration should not exceed 0.5 g / kg / h.

    For complete assimilation of dextrose entered in large doses, simultaneously assign insulin short action At the rate of 1 EDR insulin on 4-5 g dextrose.

    With full parenteral nutrition, glucose administration should always be accompanied by the introduction of a sufficient amount of amino acid solutions, lipid emulsions, electrolytes, vitamins and trace elements.

    Patients with diabetes glucose is administered under the control of its blood content and urine.

    For adults: 500-3000 ml per day.

    For children, including newborns:

    With a mass of body 0-10 kg - 100 ml / kg per day;

    With a body weight of 10-20 kg - 1000 ml + additional 50 ml per each kg of body weight Over 10 kg per day;

    With a body weight, more than 20 kg - 1500 ml + additional 20 ml per each kg of body weight over 20 kg per day.

    Speed \u200b\u200band amount of infusion depend on age, body weight, clinical condition and patient metabolism, as well as on concomitant therapy. Children should determine their attending physician who has experience intravenous drugs This category of patients.

    It is impossible to exceed the glucose utilization threshold in the body to avoid hyperglycemia, so maximum dose Dextrose varies from 5 mg / kg / min for adults and 10-18 mg / kg / min for newborns and children depending on age and total body weight.

    The recommended dose when applying for dilution and dissolve administered parenteral drugs is usually 50-250 ml per dose of the administered drug of the administered drug, but the required amount should be determined on the basis of the instructions for the use of added drugs. In this case, the dose and the rate of administration of the solution are determined by the properties and mode of dosing of the divorce drug.

    10% Glucose solution:

    Indication to application

    Initial daily dose

    Infusion speed

    As a source of carbohydrates (separately or as part of parenteral nutrition, if necessary)

    500-3000 ml per day

    (7-40 ml / kg per day)

    5 mg / kg / min (3 ml / kg / h)

    The duration of treatment depends onclinical condition of the patient

    Prevention and treatment of hypoglycemia

    Rehydration in case of fluid loss and in dehydration in patients with high care in carbohydrates

    For breeding and dissolving administered parenteral drugs

    50-250 ml per single dose of administered medicinal preparation

    Depending on the divorce drug

    Children and teenagers: The speed and volume of infusion depend on age, body weight, clinical condition and patient metabolism, as well as on concomitant therapy. They must determine the attending physician who has experience in the use of intravenous drugs in children.

    Indication K.

    Initial

    Initial infusion rate *

    application

    daily dose

    Newborn and premature children

    Infantsand childrenearlyage

    (1-23 months)

    Children

    (2-11 years)

    Teens

    (from 12 to 16-18 years)

    As a source of carbohydrates (separately or as part of parenteral nutrition, if necessary)

    - with a mass of 0-10 kg 100 ml / kg / day

    With a mass of 10 to 20 kg - 1000 ml + additional 50 ml per each kg of body weight Over 10 kg / day

    - with a mass of more than 20 kg - 1500 ml + Additional 20 ml per each kg of body weight Over 20 kg / day

    6-11

    ml / kg / h

    (10-18

    mg / kg / min)

    5-11

    ml / kg / h

    (9-18

    mg / kg / min)

    ml / kg / h

    (7-14

    mg / kg / min)

    From 4 ml / kg / h

    (7-8.5 mg / kg / min)

    Prevention and treatment of hypoglycemia

    Rehydration in case of loss of liquid and dehydration in patients with a high need for carbohydrates

    For breeding and dissolving administered parenteral drugs

    Initial dose: From 50 to 100 ml per single dose of the administered drug. Regardless of age.

    Infusion speed: Depending on the divorce drug. Regardless of age.

    * Speed, infusion volume and treatment duration depend on age, body weight, clinical condition and patient metabolism, as well as on concomitant therapy. They must determine the attending physician who has experience in the use of intravenous drugs in children.

    Note: Maximum volumes within the recommended doses should be entered within 24 hours to avoid hemodulics.

    The maximum infusion rate should not exceed the glucose utilization threshold in the patient's body, as this can lead to hyperglycemia. Depending on the clinical state of the patient, the rate of administration can be reduced to reduce the risk of osmotic diuresis.

    When using the drug for dilution and dissolve drugs for infusion administration, the required volume is determined on the basis of the instructions for the use of added drugs.

    20% glucose solution:

    The introduction of a 20% glucose solution is carried out only through the central vein. The rate of administration of the solution is up to 30-40 CAP / min (1.5-2 ml / min). Maximum daily dose for adults - 500 ml.

    40% glucose solution:

    The use of the drug should be carried out under regular medical supervision.

    Dosing mode depends on age, weight and clinical condition of the patient. Clinical and biological parameters should be carefully monitored, in particular the blood glucose concentration, electrolytes and the water-salt balance.

    A 40% glucose solution is administered intravenously drip at a speed of up to 30 CAP / min (1.5 ml / min).

    Maximum daily dose for adults - 250 ml.

    After achieving the necessary concentration of glucose glucose in the patient's blood, it is transferred to the introduction of 5% or 10% glucose solutions.

    Side effects:

    Unwanted reactions (HP) are grouped by systems and organs in accordance with the MEDDRA dictionary and the HP WHO frequency classification: very often (≥ 1/10), often (≥ 1/100 to<1/10), нечасто (≥ 1/1000 до <1/100), редко (≥ 1/10000 до <1/1000), очень редко (<1/10000), частота неизвестна - (частота не может быть определена на основе имеющихся данных).

    From the immune system

    The frequency is unknown: anaphylactic reactions, increased sensitivity.

    From the metabolism and nutrition

    The frequency is unknown: disorders of the water and electrolyte balance (hypocalemia, hypomagnemia and hypophosphatemia), hyperglycemia, hemodilution, dehydration, hypervolemia.

    From the vessels

    Frequency unknown: venous thrombosis, phlebitis.

    From the side of the skin and subcutaneous fabrics

    Frequency unknown: increased sweating.

    From the kidneys and urinary tract

    Frequency unknown: polyuria.

    General disorders and disorders in the place of administration

    The frequency is unknown: chills, fever, infection at the injection site, irritation at the injection site, extravagation, pain in the injection site.

    Laboratory- instrumental data

    Frequency unknown: glucosuria.

    Unwanted reactions can also be associated with the drug, which was added to the solution. The probability of other unwanted reactions depends on the properties of a particular drug added.

    If unwanted reactions occur, the introduction of the solution should be stopped.

    Overdose:

    Symptoms

    Prolonged infusion administration of the drug can lead to hyperglycemia, glucosuria, hyperosmolarness, osmotic diuresis and dehydration. Fast infusion can create a liquid accumulation in the body with hemodiillation and hypervolemia, and when the body's ability is exceeded, a quick administration can cause hyperglycemia. There may also be a decrease in potassium content and inorganic phosphate in blood plasma.

    When applying declarations for infusion infusion and dissolving other drugs for intravenous administration, clinical features and symptoms of overdose can be associated with the properties of the drugs used.

    Treatment

    When symptoms appear an overdose, the introduction of the solution should be suspended, assess the patient's condition, introduce a short action insulin, if necessary, to carry out supporting symptomatic therapy.

    Interaction:

    The joint use of catecholamines and steroids reduces the absorption of dextrose (glucose).

    When mixing with other drugs, it is necessary to visually monitor them for incompatibility.

    For breeding or dissolving other drugs, the drug should be applied only if there is indications of the dilution of the dextrose solution in the instructions for use on this drug. In the absence of compatibility information, the drug should not be mixed with other drugs.

    Before adding any medicinal product, it is necessary to make sure that it is soluble and stable in water in the range of the preparation. After adding a compatible drug to the preparation, the resulting solution should be administered immediately.

    Drugs with a certain incompatibility cannot be used.

    When the dextrose solutions are introduced through the same infusion system as for hemotransfusion, hemolysis and thrombosis is possible.

    Special instructions:

    Since patients with diabetes mellitus, renal failure or in acute critical state, glucose tolerance (dextrose) can be violated, their clinical and biological parameters should be particularly carefully monitored, in particular the concentration of electrolytes in the blood plasma, including magnesium or phosphorus, The concentration of glucose in the blood. If you have hyperglycemia, you should adjust the rate of administration of the drug or assign a short action insulin.

    Usually glucose is fully absorbed by the body (in the normal kidney is not excreted), therefore the appearance of glucose in the urine may be a pathological basis.

    In case of continuous administration or application of dextrose in high doses, it is necessary to control the concentration of potassium in the blood plasma and, if necessary, enter potassium additionally to avoid hypokalemia.

    In the episodes of intracranial hypertension, careful control of blood glucose concentration is necessary.

    The use of dextrose solutions can lead to hyperglycemia. Therefore, they are not recommended to be administered after an acute ischemic stroke, since hyperglycemia is associated with an increase in ischemic brain damage and prevents recovery.

    Particularly thorough clinical monitoring is required at the beginning of the intravenous administration of the drug.

    For rehydration therapy, carbohydrate solutions should be used in combination with electrolyte solutions to avoid the violation of the electrolyte balance (hypoconathemia, hypokalemia).

    It is necessary to control the concentration of glucose and the content of electrolytes in the blood, the water balance, as well as the acid-base state of the body.

    Before use, the solution should be viewed. Apply only a transparent solution without visible inclusions and in the absence of packaging damage. Enter immediately after connecting to the infusion system.

    The solution should be administered using sterile equipment in compliance with the rules of asepsis and antiseptics.

    To avoid an air embolism, remove air from the infusion system with a solution.

    Do not connect containers in series to avoid air embolism, which may arise due to air suction from the first container until the solution is completed from the solution from the second container.

    The supply of intravenous solutions contained in soft plastic containers, under increased pressure in order to increase the flow rate, can lead to an air embolism if the residual air in the container is not completely removed.

    The use of a system for intravenous administration with a gas travelery can lead to an air embolism with an open gas rifle. Soft plastic containers with such systems should not be used. The added substances can be entered before infusion or during infusion via input location (with a special port for entering drugs). Adding to a solution of other drugs or a violation of the technique of administration may cause fever due to the possible hit in the organism of pyrogen. In the development of unwanted reactions, infusion should be immediately terminated.

    When adding other drugs before parenteral administration, it is necessary to check the isotonicity of the resulting solution. Full and thorough mixing in aseptic conditions is mandatory. Solutions containing additional substances should be applied immediately, their storage is prohibited.

    With the introduction of additional nutrients, it is necessary to determine the osmolarity of the mixture obtained before the start of the infusion. The resulting mixture must be administered through the central or peripheral venous catheter, depending on the final osmolarity.

    Compatibility of additionally administered drugs must be assessed before adding them to the solution (similar to the use of other parenteral solutions). Evaluation of the compatibility of additionally administered drugs with the drug is included in the competence of the doctor. It is necessary to check the resulting solution to change the color and / or the appearance of precipitate, insoluble complexes or crystals.

    You should explore the instructions for the use of added drugs.

    From a microbiological point of view, the divorced drug should be applied immediately. The exception is breeding prepared in controlled and aseptic conditions. After the preparation of the solution, the timing and conditions for its storage before the introduction are the responsibility of the user and should be not more than 24 hours at a temperature of from 2 to 8 ° C.

    Children

    For newborns, especially in premature or born with low body weight, increased risk of hyperium or hyperglycemia, therefore, during intravenous administration of dextrose solutions, careful control of blood glucose concentration is needed to avoid remote undesirable consequences. Hypoglycemia in newborns can lead to lengthy cramps, coma and damage to the brain. Hyperglycemia is associated with intraventricular hemorrhage, delayed bacterial and fungal infectious diseases, retinopathy of premature, necrotic enterocolitis, bronchopulating dysplasia, long-term hospitalization and mortality.

    In order to avoid potentially lethal overdose of intravenous drugs, newborn, special attention should be paid to the method of application.

    When used for intravenous administration of drugs, the newborn syringe pump container with a solution cannot be left connected to the syringe. When using an infusion pump before removing the system from a pump or shutdown it, it is necessary to close all system clamps, regardless of the presence in the system of a device that prevents the free current fluid.

    Devices for intravenous infusion and other equipment for the introduction of drugs should be regularly monitored.

    If the drug contains dextrose derived from corn, the use of the drug is contraindicated to patients with well-known corn intolerance or corn products, because The following manifestations of hypersensitivity are possible: anaphylactic reactions, chills and fever.

    For preparations in containers:

    Containers should be disposed of after one-time application.

    It should be disposed of each unused dose.

    Do not connect repeatedly used containers.

    Impact on the ability to control the transc. cf. And Meh.:

    Not applicable (due to the use of the drug exclusively in the hospital).

    Release form / Dosage:

    Solution for infusions, 5%, 10%, 20%, 40%.

    Packaging:

    250 and 500 ml into containers from a multilayer polymer film compounded with multilayer polymer tubes and infusion ports.

    Each container, together with the instructions for use, is placed in an individual package of polymer and combined materials.

    10-90 containers are placed in a package of polymeric and combined materials together with an equal number of instructions for use or 10-90 individual packages with containers are placed in a package of polymer and combined materials (for hospitals only).

    Storage conditions:

    At temperatures from 5 to 30 ° C.

    Keep out of the reach of children.

    Shelf life:

    3 years.

    Do not use after the expiration date.

    Conditions of vacation from pharmacies:On prescription

      Glucose is very well and quickly absorbed by the body, as well as saturates its energy. To quickly restore it forces and use it. Apply it in many illnesses. Such as: in stress, shortage of sugar, with low pressure, with poor liver and heart performance.

      Glucose This is a very easily digestible power source for the human body, which can increase both energy reserves and improve the functionality of the body.

      Glucose droppers are used for disinfecting, i.e. the output of toxins from the human body and to replenish the fluid lost in it.

      In the form of general supporting glucose therapy, it is used if a person has general physical exhaustion occurs.

      Glucose solution can be assigned at:

      inxications and poisoning

      when hepatitis and liver diseases

      for diseases of blood system

      with a strong diarrhea

      and other problems.

      Glucose refers to substances that quickly fill the shortage of food in the human body to raise the tone and increase energy.

      Once I put a dropper with glucose in poisoning, as the well-being was just a terrible and tremendous decline. I agree with one answer that glucose is not prescribed for the disintellation of the body. The most important task of glucose is to give food as soon as possible.

      As far as I know, glucose is very useful under reduced blood pressure.

      Glucose is a source of energy that is most versatile, as it is easily absorbed, because it is susceptible to fast splitting in the body.

      Glucose drip:

      1) with different kinds of intoxication and poisoning;

      2) in case of falling blood pressure in order to improve blood pressure;

      3) when impaired heart work;

      4) in disruption of functioning A \u003d liver;

      5) to increase the level of sugar, if it has decreased significantly;

      6) after severe stressful situations;

      7) in the exhaustion of the body in order to normalize metabolism.

      Most often, it is dripping glucose to remove signs intoxication, that is, to destroy toxins in the body or wash unwanted medicines. Very effective and high-speed method. Also drip after operations to speed up the healing of soft tissues.

      I came across several times with the need to prick glucose my animals. The fact is that this is a good power source. If for some reason, for example, animals cannot eat to support their health E drip, such images are essentially feeding.

      Dropper with glucose put a person in some diseases.

      Glucose is administered intravenously with hypoglycemia when the blood sugar level is understated. It is necessary for those who have infectious diseases.

      Glucose is administered with a sharp decrease in the pump function of the heart (the decompensation of cardiac activity).

      Glucose is necessary in diseases of the liver, pulmonary edema, hemorrhagic diathesis (increased bleeding), shock and sharp decay of blood pressure (collapse).

      The glucose solution is used mainly to replenish the fluid in the body. Capels are prescribed when

      reduced blood glucose level

      sharp lower blood pressure

      increased bleeding

      in the postoperative period

      poisonings provoked by microbes that hit the body with food

      Glucose droppers are used in medicine for a long time.

      Glucose is a source of energy that is easily absorbed. Studies were also conducted, which proved that glucose removes stress.

      The glucose dropper is in the following cases:

      first, to improve blood pressure, with a sharp drop in blood pressure,

      secondly, to improve the liver, after the dropper it works better,

      thirdly, to improve the metabolism in the human body, as well as in the exhaustion of the body,

      fourth, to improve the work of the heart muscle,

      fifth, if the blood sugar level has decreased strongly,

      sixth, if a person is in a shock,

      v-seventh, with alcohol poisoning.

      Glucose is a universal source of energy, as it is immediately split in the body, it is very easily absorbed. What is written is that for disinteling or replenishing the liquid - nonsense of a silent mare, since a solution of glucose, almost immediately comes out of the bloodstream (5-10 minutes after the blood flow) in the tissue, where the metobolized, providing cells The necessary energy, in addition, pulls the water, so it is impossible to put it in any way. For disinfection, more crystalloids of at least colloids are used (for example, ordinary saline, reosorbilact, sorbilact, refooliglukin, ringer, etc.). A 5% glucose solution is used.

      It is also used by a 40% solution that is administered intravenously in the hypoglycemic coma (as a rule, with insulin overdose), the patient literally at the end of the needle, as soon as you start entering comes to yourself. It is an excellent means for removing the acetional syndrome in children, as soon as he heard the smell of acetone from the mouth, we give a child to drink 10ml 40% glucose, if everything is done in time, vomiting, etc. Will avoid.