Thanks

The site provides reference information for informational purposes only. Diagnosis and treatment of diseases should be carried out under the supervision of a specialist. All drugs have contraindications. Expert advice is required!

Asparkam is a source of potassium and magnesium, because it contains these elements in a form that allows them to pass into the cells and be completely absorbed. The drug restores the electrolyte balance, if it has been disturbed, and is a source of potassium and magnesium for the body.

Potassium has an antiarrhythmic effect, thereby maintaining normal and regular heart function without arrhythmias. Magnesium is involved in ensuring the flow of more than 300 different biological reactions in the human body, necessary to maintain life and normal metabolism. In addition, magnesium improves the penetration of potassium ions into cells.

Asparkam is used for heart failure, myocardial infarction, arrhythmias, to eliminate the effects of intoxication caused by the use of cardiac glycosides (Strophanthin, Digoxin, Korglikon, Digitoxin, Celonide, etc.), as well as to restore the balance of ions with a deficiency of potassium (hypokalemia) and magnesium ( hypomagnesemia) in the body.

Asparkam - composition, forms of release, dosage, varieties

Today, under one common name "Asparkam" means several varieties of the drug, produced by various pharmaceutical companies under different names. As a rule, these names always contain the word "Asparkam", to which are added several letters related to the multiple name of the enterprise that manufactures this particular drug, for example, "Asparkam-Ferein", "Asparkam-Farmak", etc. All these varieties of the drug differ from each other only in the names given to them by the heads of enterprises, since they are manufactured using the same technology developed in the USSR.

Different names for the same Asparkam are necessary in order to register the products of a pharmaceutical company on the market. The fact is that during the Soviet period, all pharmaceutical plants produced drugs using the same technologies and under the same name, for example, acetylsalicylic acid was only called that, although it could have been produced in Nizhny Novgorod, Perm, Novokuznetsk, etc. And now each plant has become a separate enterprise and it needs to register its unique drug names. And since many of these drugs have been produced since the USSR period, their names are not fundamentally changed, but letters or words are simply added so that they are considered unique. But, in fact, this is all the same drug, manufactured using the same technology by different pharmaceutical plants.

In addition, some varieties of Asparkam can be produced in only one dosage form, since the company has developed the production technology of this particular form, and not any other. For example, "Asparkam-Farmak" and "Asparkam-Ferein" are produced only in the form of a solution for injection, and tablets are not produced at these pharmaceutical enterprises, since the necessary technology is not available or there is no way to master it.

So, at present, various pharmaceutical factories produce the following varieties of Asparkam:

• Asparkam;
• Asparkam-L;
• Asparkam-ROS;
• Asparkam-UBF;
• Asparkam-Farmak;
• Asparkam-Verein.

These varieties of the same drug differ only in names, therefore, in the following text, we will designate them all with one common name "Asparkam".

Varieties of Asparkam are available in the following dosage forms:

• Tablets for oral administration (Asparkam, Asparkam-ROS, Asparkam-UBF);
• Solution for intravenous injection in ampoules of 5 ml, 10 ml and 20 ml (Asparkam, Asparkam-L, Asparkam-Farmak, Asparkam-Ferein);
• Solution for intravenous infusion - "droppers" in bottles of 200 ml and 400 ml (Asparkam-L).

The composition of all forms of Asparkam includes two compounds - potassium aspartate And magnesium aspartate. These compounds are salts of potassium and magnesium, which penetrate well into cells due to asparaginate. In the process of penetration into the cell, potassium and magnesium ions are released from asparaginate, and therefore they are the main active ingredients of the drug.

Various dosage forms Asparkama contains the following amounts of potassium and magnesium in the form of aspartate:

• Tablets - 175 mg of potassium aspartate and 175 mg of magnesium aspartate (175 + 175);
• Solution for injection - 40 mg of magnesium aspartate (3.37 mg of pure magnesium) and 45.2 mg of potassium aspartate (10.33 mg of pure potassium) in 1 ml;
• Solution for infusion - 7.9 g of magnesium aspartate and 11.6 g of potassium aspartate in 1 liter.

Asparkam tablets have a specific smell, and contain corn starch, calcium stearate, talc and polysorbate-80 as auxiliary components. Solutions for injections and infusions contain only sorbitol and sterile water as auxiliary components.

Therapeutic effects of Asparkam

Asparkam is a source of potassium and magnesium ions, respectively, its therapeutic effects due to the action of these chemical elements. First of all, Asparkam eliminates the imbalance or deficiency of potassium and magnesium in the body, and also has the ability to regulate metabolic processes, since these ions are involved in many biochemical reactions in all organs and tissues.

Potassium is the main intracellular positive ion in all organs and tissues. Being inside the cell in sufficient quantity, potassium stimulates the synthesis of ATP (adenosine triphosphoric acid), glycogen, proteins and acetylcholine.

ATP is a universal energy molecule that is necessary for any reactions to occur and the functions of a cell to function. In terms of its role, ATP can be compared to gasoline for a car engine. That is, without ATP, the cell simply cannot do anything, even provide its own nutrition and reproduction. Potassium, by stimulating the synthesis of ATP, allows the cell to receive a large amount of energy, which is enough to perform specific functions (for example, muscle contractions, production of of hydrochloric acid etc.), and on the formation of molecules for their own nutrition, and on the replacement of "old", "worn out" proteins with new ones.

Stimulation of glycogen synthesis allows the cell to create a strategic supply of a substance that can be quickly converted into ATP during hunger. That is, under the influence of potassium, the cells create reserves of a kind of "semi-finished products" for periods of life when there is little energy.

Stimulation of protein synthesis allows the cell to timely replace the "old" molecules, which are already poorly coping with their functions, with new ones that have the ability to work quickly and easily. This phenomenon can be compared to replacing old and worn parts on a car or any other device. Naturally, after replacing old parts with new ones, the device will work better. The same is true in the cells of the body - replacing old proteins with new ones allows cellular elements to work better, more efficiently and longer.

Stimulation of the synthesis of acetylcholine allows the cell to accelerate the conduction of various signals along nerve fibers, since it is this substance that is the mediator that performs the function of nerve activation.

Thus, potassium ions accelerate the work of the cell, increase its efficiency, and also allow you to quickly respond to commands from the nerve trunks and create reserves of energy substances.

Magnesium is necessary for the work of more than 300 enzymes that provide metabolism and the implementation of the specific functions of each cell in the body. Magnesium is also involved in the cascade of reactions for the synthesis of ATP and regulates the balance of potassium. Thus, magnesium enhances the effects of potassium and makes the work of the cell more efficient, faster and more versatile.

In addition, potassium and magnesium ions together maintain the necessary polarization of cell membranes, which is necessary for the effective separation of the external environment and the internal cell cytoplasm. Due to this separation of environments, unnecessary and harmful substances, and metabolic products are removed from it to the outside.

Aspartate is a carrier of potassium and magnesium ions across the membrane into cells. After penetration into the cell, potassium and magnesium are released from the bond with aspartate, and it is included in the metabolic process. Aspartate improves the synthesis of replaceable amino acids, nucleotides for DNA and lipids. In addition, aspartate optimizes energy metabolism in the heart muscle experiencing oxygen starvation, for example, in ischemic disease, atherosclerosis, etc.

It should be remembered that Asparkam has all of the above effects in the cells of all organs and tissues, but they are most noticeable in relation to the heart. Therefore, Asparkam is traditionally used in complex treatment heart diseases, especially arrhythmias, since in relation to this most important organ it has the following effects:

• Prevents and eliminates hypokalemia (potassium deficiency in the blood);
• Improves metabolism in the heart muscle;
• Eliminates arrhythmias that occur after myocardial infarction or against the background of heart failure;
• Improves the tolerance of cardiac glycosides (Strophanthin, Digoxin, Korglikon, Digitoxin, Celanide, etc.);
• It increases the endurance of the heart and allows you to perform more physical work and endure much stronger emotions.

Asparkam - indications for use (what is used for)

Asparkam is indicated for use in complex therapy the following diseases and conditions:

• Heart failure;
• Ischemic heart disease (CHD);
• Postinfarction period;
• Violations heart rate(paroxysmal supraventricular tachycardia, atrial and ventricular extrasystoles) caused by various causes, including myocardial infarction and an overdose of cardiac glycosides;
• Digitalis intoxication (poor tolerance or poisoning with cardiac glycosides).

In addition, Asparkam as an independent drug is indicated for use in hypokalemia (potassium content in the blood is below normal) and hypomagnesemia (magnesium content in the blood is below normal) of any origin. With hypomagnesemia and hypokalemia, Asparkam is used until the concentration of magnesium and potassium ions in the blood is normalized. You should be aware that Asparkam can be used to eliminate potassium and magnesium deficiency of any origin, for example, after repeated vomiting, diarrhea, taking non-potassium-sparing diuretics (for example, Furosemide), laxatives and glucocorticosteroids.

In addition, it is separately necessary to highlight recommendations (which can be conditionally considered indications for use) on the use of Asparkam in sports:

• Prolonged and intense physical activity;
• overtraining;
• Cardiopsychoneurosis;
• Violation of the heart rhythm.

Asparkam - instructions for use

Consider the rules for the use of various dosage forms of Asparkam in separate sections to avoid confusion.

Asparkam tablets

Tablets should be swallowed whole, without biting, chewing, breaking or crushing in other ways, but with a small amount of water (half a glass is enough).

Asparkam is taken for the prevention of potassium and magnesium deficiency, as well as in sports, 1 tablet 3 times a day after meals. The duration of prophylactic administration is determined individually and can be long. When taking Asparkam for more than 4 weeks, it is recommended to take a blood test every 7 to 14 days to determine the concentration of potassium and magnesium. If they are at the upper limit of the norm or slightly exceed it, then you should stop taking Asparkam for a while. In such a situation, it will be possible to resume taking the drug only when the concentrations of potassium and magnesium in the blood drop to normal values.

Neither for therapeutic nor prophylactic purposes, more than 6 Asparkam tablets per day should be taken, since excessively high dosages of potassium and magnesium are not absorbed, but simply excreted in the urine. That is, 6 tablets taken during the day will be absorbed, and all the rest will simply be removed from the body. Attempts to take more than 6 Asparkam tablets per day only lead to increased stress on the kidneys, which can adversely affect their functioning and, accordingly, the well-being of a person.

Instructions for use of solutions for intravenous injections and infusions

Solutions for infusion and injection are administered intravenously exclusively for treatment and never for prevention and in sports. In order to increase heart endurance and prevent potassium and magnesium deficiency, Asparkam should be taken only in tablets.

Solutions for injection are available in 5 ml, 10 ml and 20 ml ampoules under the names Asparkam, Asparkam-L, Asparkam-Farmak, Asparkam-Ferein and have the same concentrations of potassium and magnesium. The solution for infusion is available in 200 ml and 400 ml bottles under the name Asparkam-L.

Solutions for injection can be administered by bolus (slowly release a jet directly from the syringe) or used to prepare a solution for infusion ("droppers"). The solution for infusion is used only for drip administration, that is, for what is commonly called a "dropper".

Only clear solutions for injection and infusion should be used. If there is a cloudy solution in the bottle or ampoule, then it should be discarded. After opening the ampoule or bottle, you must immediately use the solution. If, after mixing Asparkam in one syringe or bottle with other infusion solutions, they become cloudy, then such mixtures cannot be administered, they must be thrown away.

For therapeutic purposes as part of complex therapy various diseases heart solutions for injection Asparkam administered daily 10 - 20 ml 1 - 2 times a day for five days. Before administration, half the amount of saline or 5% dextrose solution is added to Asparkam, for example, 5 ml of saline or 5% dextrose solution are taken per 10 ml of Asparkam, etc. Ampoules with the required amount of Asparkam are opened immediately before the injection and the required amount of solution is drawn from them into a syringe with a thin needle. Then half the amount of physiological saline or 5% dextrose solution is drawn into the same syringe, after which its contents are gently mixed by tilting in different directions. Then the finished solution is injected into the vein slowly, at a rate of at least 5 ml per minute.

The solution for infusion is used only for "droppers", that is, it is administered intravenously by drip. FROM medicinal purposes 300 ml of the prepared solution for infusion is administered 1-2 times a day for a maximum of 5 days. The solution is injected at a rate of 20 - 30 drops per minute (1 - 1.5 ml per minute).

If for some reason there is no solution for infusion, but it is necessary to administer Asparkam to a person in the form of a "dropper", then ampoules with a solution for injection can be used. In this case, the solution for infusion is prepared from the solution for injection. To do this, for every 10 ml of injection solution from ampoules, add 100 ml of saline or 5% dextrose solution.

That is, if a person needs to inject 300 ml of an infusion solution, then to obtain it, 30 ml of an injection solution should be poured from the ampoules and 300 ml of physiological saline should be added to it. The infusion solution thus obtained is also injected at a rate of 20-30 drops per minute.

Special instructions and precautions

Asparkam in any dosage form should be used with caution and only under the supervision of a physician if a person has the following diseases and conditions:

• AV block (atrioventricular block);
• Severe liver failure;
• metabolic acidosis of the blood;
• High risk of edema;
• Impaired kidney function;
• Low levels of phosphate in the blood.

When using Asparkam in combination with potassium-sparing diuretics (for example, Veroshpiron, Spironolactone, etc.), ACE inhibitors(Captopril, Ramipril, Enalapril, etc.), beta-blockers (Nebilet, Concor, Anaprilin, Betaloc ZOK, etc.) and Cyclosporine should control the concentration of potassium in the blood.

Overdose

An overdose of Asparkam is possible only with intravenous administration of solutions and is manifested by the following symptoms:

• Bradycardia (slow heartbeat);
• decline blood pressure;
• vascular collapse;
• diastolic cardiac arrest;
• Vomit;
• Lethargy;
• Weakness of the bladder;
• heart block;
• Respiratory paralysis;
• Paralysis of the heart muscle with cardiac arrest.

To treat an overdose of Asparkam, a solution of calcium chloride should be administered intravenously, which neutralizes the excess of potassium and magnesium ions. It is possible to accelerate the excretion of ions with the help of hemodialysis.

When taking tablets, an overdose of Asparkam has never been recorded.

Interaction with other drugs

The use of Asparkam inhibits intestinal motility and provokes constipation, and also increases the risk of hyperkalemia ( elevated level potassium in the blood) due to excessive accumulation of potassium ions in the blood in combination with the following drugs:

• Potassium-sparing diuretics (for example, Veroshpiron, Spironolactone, etc.);
• ACE inhibitors (Captopril, Ramipril, Enalapril, etc.);
• Beta-blockers (Nebilet, Concor, Anaprilin, Betalok ZOK, etc.);
• NSAIDs (Aspirin, Indomethacin, Paracetamol, Ibuprofen, Nimesulide, etc.);
• Cyclosporine.

Asparkam slows down the absorption of tetracycline, iron preparations and sodium fluoride. In order for these drugs to be absorbed at a normal rate, they should be taken at a three-hour interval relative to Asparkam's intake.

Asparkam reduces toxicity and improves the tolerability of cardiac glycosides by eliminating their side effects.

When using non-potassium-sparing diuretics (Furosemide, etc.) and glucocorticosteroids (Dexamethasone, Prednisolone, etc.), simultaneous administration of Asparkam replenishes potassium losses and prevents hypokalemia.

Asparkam enhances the effects of antidepolarizing muscle relaxants (Pipecuronium, Pancuronium, Tubocurarine, etc.) and anesthetics (Ketamine, Hexenal, etc.), but reduces the severity of the action of antibiotics Neomycin, Polymyxin B, Tetracycline and Streptomycin.

Asparkam for children and infants

Asparks for children older than a year and infants are prescribed only in cases where a deficiency of potassium in the blood (hypokalemia) is detected according to the results of laboratory tests. If, according to the results of a blood test for ions, hypokalemia was detected, then, regardless of the reasons that provoked this violation, the child is prescribed Asparkam tablets. Intravenous injections are extremely rare, only in case of a life-threatening situation.

Hypokalemia in children is manifested by lethargy, drowsiness, apathy, muscle weakness, a drop in blood pressure, arrhythmia and tachycardia (palpitations). If the child is breastfeeding, then in addition to the indicated signs, hypokalemia can be manifested by dry skin, increased gas formation, poor breast sucking and frequent regurgitation, up to vomiting.

Hypokalemia in a child of any age can develop for the following reasons:

• repeated vomiting;
• Diarrhea for at least a day;
• severe liver or kidney disease;
• Diseases of the digestive tract;
• The use of glucocorticoids;
• The use of non-potassium-sparing diuretics;
• Intravenous administration of solutions of glucose, proteins and salts without potassium.

If a child has recently been exposed to the possible above-mentioned causative factors of hypokalemia, then you should donate blood for an ionogram, during which the doctor will determine the concentration of potassium. If it is low or close to the lower limit of the norm, then it is necessary to drink a 1-2 week course of Asparkam in individual dosages that the doctor will prescribe. The drug is also prescribed to children for the relief of arrhythmia caused by myocarditis, which usually develops as a complication of a viral or bacterial infection.

As a rule, with hypokalemia and arrhythmia, children are recommended to give Asparkam for 1 to 2 weeks in the following dosages:

• Children under one year old- 1/4 tablet 1 time per day;
• Children 1 – 3 years old- 1/2 tablet 1 time per day;
• Children 3 – 6 years old- 1/2 tablet 2 times a day;
• Children 7 – 10 years old- 1/2 tablet 3 times a day;
• Children 11 - 12 years old- 1 tablet 1 - 2 times a day;
• Children 13 - 16 years old- 1 tablet 2 times a day;
• Children 16 years old- 1 tablet 3 times a day.

These dosages are only indicative, therefore, in each case, it is better to consult a doctor who will determine the individual dosage, taking into account the characteristics of the child.

If a child is taking diuretics or glucocorticoids that promote the excretion of potassium from the body, then doctors always additionally prescribe Asparkam in prophylactic dosages to prevent the development of hypokalemia. The combination Diakarb (diuretic drug) + Asparkam has become literally a classic, prescribed for infants to reduce increased intracranial pressure. In this case, Asparkam and Diakarb are prescribed according to a certain scheme for a long time.

Application during pregnancy

The instructions for use indicate that Asparkam can be used during pregnancy with caution. This is quite true, since Asparkam does not harm the fetus and mother, if used according to indications, and not just like that, "for prevention." Preventive admission courses this drug during pregnancy, it is not worth producing, since this can lead to an imbalance of ions, for example, an increase in the concentration of potassium and magnesium in the blood above the norm, which, in turn, can provoke severe complications up to pregnancy loss.

Asparkam during pregnancy can be taken simultaneously with non-potassium-sparing diuretics, as well as to improve heart function if functional disorders are detected on the ECG. In addition, you can use Asparkam in short courses of 1 to 2 weeks to prevent hypokalemia if a woman often has vomiting or diarrhea. In such cases, it is optimal to take 1 tablet of Asparkam 3 times a day for a week after 2 episodes of vomiting or diarrhea.

Application for various purposes not indicated in the instructions

Asparkam and Riboxin + Asparkam in bodybuilding

In bodybuilding or sports, Asparkam alone or in combination with Riboxin is taken to increase endurance, increase the time of effective training, as well as strength and cardio loads. In addition, Asparkam alone or in combination with Riboxin improves the condition and increases the productivity of the athlete's heart, preparing and adapting it to high physical exertion, which, in turn, prevents sudden death from cardiac arrest due to the fact that the body simply could not stand it. loads.

Asparkam is a source of potassium and magnesium, which reduce the heart rate and allow you to keep your heart rate within the required limits during exercise. That is, when using Asparkam, even against the background of an intense power or cardio load, the heart does not beat as often and strongly as without this drug. In addition, potassium and magnesium ions well relax muscles, eliminate excessive tension and relieve cramps. And since potassium and magnesium are intensively consumed with any power loads, taking Asparkam allows you to replenish the level of ions in the blood and cells and make training more effective.

Riboxin increases the volume of ejected blood and the force of contractions of the heart, which improves the blood supply to all organs and tissues in the body. In addition, Riboxin provides muscle recovery after intense training, stops arrhythmias and helps restore the structure of myocardial cells, which eliminates cardiomyopathy. Separately, it is worth noting the anabolic effect of the drug, which is useful for athletes and bodybuilders, which allows you to quickly gain muscle mass.

Thus, both drugs are useful for athletes and bodybuilders, but most often they are used in combination, since Asparkam further enhances the effects of Riboxin. Asparkam is recommended to take 1 tablet 3 times a day for a month, and Riboxin - 2 tablets 3 times a day also for a month. Courses of taking each drug separately or a mixture of Asparkam + Riboxin can be repeated every 3 months.

Asparkam for weight loss

Currently, the drug is quite widely used for weight loss, with some people combining it with diet and exercise, while others with diuretics.

Taking Asparkam in order to accelerate weight loss and achieve better results while following a diet, especially a strict diet, and exercise justified and helpful. The fact is that when following a diet, a person does not receive many of the substances he needs in sufficient quantities, including potassium and magnesium, which slows down the metabolism and prolongs the process of losing weight.

Asparkam allows you to make up for the deficiency of these elements in food and ensure their intake in the body in sufficient quantities. And the potassium and magnesium contained in Asparkam enhance the effect of diet and exercise, as they speed up metabolism, optimize muscle function and accelerate the elimination of toxins formed as a result of the breakdown of fat cells, as a result of which a person taking Asparkam will lose weight faster and stronger than the one who does not use this drug.

Thus, the use of Asparkam for weight loss in combination with diet and exercise is rational and beneficial. In this case, the drug is recommended to take 1 tablet 3 times a day for 2 to 4 weeks.

The use of diuretic drugs (Furosemide, Diakarba and others) in combination with Asparkam for the purpose of losing weight is unjustified and dangerous. The fact is that under the influence of diuretics, fluid is excreted from the body and dehydration occurs. Of course, as a result of this technique, the weight can be reduced by several kilograms, but due to dehydration, and not the breakdown of body fat, which in itself is dangerous. In this case, Asparkam only prevents a decrease in the concentration of potassium in the blood, since these ions are excreted by the kidneys under the action of diuretics, but does not compensate for fluid loss and does not prevent dangerous consequences dehydration.

How to take Asparkam with diuretics?

Diacarb or Furosemide and Asparkam

Diakarb + Asparkam and Furosemide + Asparkam combinations are most often prescribed in the complex therapy of high blood pressure and edema, including the brain, with the main active drug it contains Diacarb or Furosemide. In addition, this combination of drugs is used in all cases where the use of diuretics is necessary.

The fact is that Diacarb and Furosemide are diuretic drugs, and therefore effectively remove fluid from the body, thereby reducing the volume of circulating blood, which naturally leads to a decrease in blood pressure. In addition, in response to a decrease in the volume of circulating blood, water from the tissues also begins to leave and flow into the bloodstream, which, in turn, eliminates swelling.

Asparkam in these combinations is necessary to replenish potassium in the blood, since Diacarb and Furosemide remove this trace element from the body. That is, Asparkam neutralizes the side effect of Diakarb and Furosemide, which allows the use of a diuretic for a sufficiently long period of time necessary to achieve the desired clinical effect.

Diakarb and Asparkam for babies

Diakarb and Asparkam are prescribed for infants to reduce intracranial pressure, eliminate cysts and brain dysfunction, as well as remove excess fluid from the ventricles of the brain. Under the action of Diakarb, water is excreted from the body, as a result of which the fluid from the tissues (in this case, the brain) enters the bloodstream, and cerebral edema, high blood pressure and the cysts are eliminated.

Diacarb must be used in combination with Asparkam, since it removes potassium from the body, and its deficiency can lead to serious complications, up to cardiac arrest. And in order to prevent potassium deficiency, together with Diakarb, you need to use Asparkam, which is a source of magnesium and potassium ions, which allows you to replenish their amount in the body.

Diakarb and Asparkam are prescribed to infants according to the following schemes:
1. Take 1/4 Asparkam tablet and 1/4 Diakarba tablet per day every three days for a month. That is, you should give the child drugs for one day, not give them for three days, etc.

bradycardia;

Lowering blood pressure;

redness of the face;

Development of hyperkalemia or hypermagnesemia (only for intravenous administration).

Data side effects almost always pass with a decrease in the dose of Asparkam.

Contraindications for use

The use of Asparkam is contraindicated if a person has the following conditions and diseases:

• Acute or chronic renal failure;
• low blood pressure (for injection);
• Hyperkalemia (increased levels of potassium in the blood);
• Hypermagnesemia (increased levels of magnesium in the blood);
• Small amount of urine (less than 1 liter per day);
• Atrioventricular blockade of 2-3 degrees;
• Hemolysis (destruction) of red blood cells;
• Adrenal insufficiency;
• Acute blood acidosis;
• Dehydration;
• Severe myasthenia gravis;
• methanol poisoning;
• Addison's syndrome;
• Violation of amino acid metabolism.

Analogues

In the domestic pharmaceutical market, analogues of Asparkam include preparations that also contain potassium aspartate and magnesium aspartate as active substances. Such analogues of Asparkam include the following drugs:

• Aspangin;
• Potassium and magnesium asparaginate Berlin-Chemie;
• Potassium and magnesium asparaginate;
• Pamaton;
• Panangin;
• Panangin Forte.

Asparkam - reviews

Almost all reviews of Asparkam (more than 97%) are positive, due to the pronounced and clearly visible clinical effects of the drug, which significantly improve general state human, normalize the work of the heart, eliminate convulsions and a number of other unpleasant symptoms due to a lack of potassium and magnesium.

Most of the positive feedback about Asparkam concerns its use in serious illnesses or functional disorders of the heart. People who took Asparkam in the complex therapy of coronary insufficiency, coronary artery disease and other severe heart pathologies note that they began to feel much better, their tolerance for physical and emotional stress increased, and the sensations of palpitations and fading disappeared. And people who took Asparkam for functional disorders of the heart (for example, a feeling of pain, fading, frantic or uneven heartbeat, myocardial dystrophy, a sharp increase in heart rate during physical and emotional stress, etc.), note that the drug completely eliminated all negative symptoms and normalized the indicators of analyzes and examinations. After a course of taking Asparkam, people suffering from functional disorders the work of the heart, because of which they did not receive admission to sports training or it was difficult to do it, became completely healthy, and doctors allowed them physical activity in any amount.

A slightly smaller part of the reviews about Asparkam concerns its effectiveness in eliminating cramps in the limbs that occur for various reasons. In the reviews, people note that literally after 2 to 3 weeks of use, the drug completely eliminated cramps and muscle tension, which prevent them from working normally, sleeping and relaxing well. Asparkam is effective for stopping seizures in pregnant women.

Women note that Asparkam reduces breast swelling and fluid retention in the body before menstruation, and also reduces the severity of other symptoms

Part Asparkam tablets includes 0.175 g of each of the active substances, as well as corn starch, talc, calcium stearate and polysorbate-80.

Part Asparkama issued in the form solution for and, includes anhydrous magnesium aspartate and anhydrous potassium aspartate at a concentration of 40 and 45.2 mg / ml, respectively (equivalent to 3.37 mg of magnesium and 10.33 mg of potassium), as well as the additive E 420 (sorbitol) and water for injection.

Release form

PJSC "Galichpharm" produces the drug in the form of tablets and a solution for injections.

Tablets are white in color with a specific odor, have a flat-cylindrical shape and a smooth surface, with a risk along the diameter. Packaged in 50 pcs. in blisters, one blister per pack.

The solution for injection is in the form of a white or slightly yellowish liquid. It goes on sale in 5 or 10 ml ampoules (packaging No. 10).

pharmachologic effect

The drug K and Mg, regulates metabolic processes.

Pharmacodynamics and pharmacokinetics

Asparkam - what is it?

Asparkam is a drug that has antiarrhythmic properties . It is used as an additional source of potassium and magnesium, as well as to restore electrolyte balance (in case it has been disturbed).

Pharmacodynamics

The therapeutic effects of the drug are determined by the properties of its constituent asparaginates. Potassium and magnesium in this form easily penetrate into the intracellular space, replenishing the deficiency of potassium and magnesium and restoring the disturbed balance of electrolytes.

Asparkam lowers the conductivity and excitability of the heart, improves metabolism in it and its sensitivity to cardiac glycosides and their toxicity. Renders moderate antiarrhythmic action and contributes to the improvement coronary circulation .

Mg2+ ions activate sodium-potassium ATP (adenosine triphosphatase). In this connection, the concentration of Na + ions in the intracellular space decreases and the flow of K + ions into cells increases.

Due to a decrease in the concentration of Na + ions inside the cell, the exchange of Ca2 + and Na + ions in the smooth muscles of the vascular walls is inhibited, which leads to their relaxation. K+ ions stimulate the synthesis of adenosine triphosphatase, glycogen, acetylcholine, and proteins.

Penetrating into the cell, aspartate participates in metabolic processes, promotes the formation of amino sugars, amino acids, nitrogen-containing lipids and nucleotides, and also corrects disturbed energy metabolism in ischemic heart muscle .

Pharmacodynamics

Absorption of the drug is fast and complete. Metabolic products are excreted mainly by the kidneys. Indicators of serum concentration of Mg and K reach peak values ​​in an hour or two after taking the medicine.

From the bloodstream, the drug enters the muscle cells of the heart in the form of Mg2+, K+ and aspartate ions, and there it is included in metabolic processes.

Indications for the use of Asparkam

Asparkam tablets - what are they from?

Wikipedia to the question “What are Asparkam tablets for?” replies that the drug is intended to compensate for the deficiency of Mg2+ and K+, including ischemic heart disease , acute THEM , CHF , (including those resulting from an overdose) cardiac glycosides ).

The manufacturer's annotation lists the following indications for the use of Asparkam tablets:

• heart failure ;
• post-infarction conditions ;
• arrhythmias provoked by electrolyte imbalances (mainly ventricular);
• conditions that accompany hypomagnesium- or hypokalemia (including overdose) saluretics ).

The use of Asparkam in tablets also allows you to increase the effectiveness and improve the tolerability of cardiac glycosides. therefore, the drug is often prescribed as an addition to them.

When taking Asparkam, the risk of developing cerebrovascular pathology (subarachnoid hemorrhage , hemorrhages in the brain , cerebral infarction ) with a lethal outcome.

In all the above cases, the drug is prescribed as part of complex therapy.

Monotherapy is indicated for hypomagnesemia And hypokalemia of any origin (including after repeated vomiting, taking laxatives, corticosteroids and non-potassium-sparing ("loop" and thiazide) diuretics). It is advisable to take the drug until the concentration of K+ and Mg2+ ions in the blood normalizes.

Asparkam solution: what is the injectable form of the drug used for?

The d / i solution has the same indications for use as the tablet form of Asparkam. It is used as an adjunct to the main treatment for arrhythmias , heart failure , THEM.

The use of cardiac glycosides against the background of therapy allows minimizing the risk of developing their inherent side effects and overdose of the latter.

Asparkam: what is this medicine used for in sports?

The instructions indicate that Asparkam is intended for the treatment of people with pathologies that are the result of a deficiency of K and Mg. In this case, the question arises by itself: “Why do they drink it in sports?”.

According to the Sports Wiki, Asparkam in bodybuilding (and other strength sports) is taken to maintain heart muscle with prolonged intense physical activity, at arrhythmias , neurocirculatory dystonia , as well as in maladaptation (conditions that are the result of overtraining).

The need to use the drug in athletes is due to the fact that the latter are often prone to the development of hypokalemia, which manifests itself in the form of convulsions, muscle weakness, cardiac arrhythmias .

One of the reasons for the loss of potassium in athletes is the peculiarities of nutrition, namely a high-protein diet: during the breakdown of proteins, toxic substances are formed, which greatly “load” the kidneys and liver and for the excretion of which the body must receive as much liquid as possible.

At the same time, not only toxins are excreted in the urine, but also inorganic ions (including K + ions).

The second reason for the development of this condition is the loss of K+ and Mg2+ ions through sweat during intense training.

Thus, in bodybuilding, when, due to the peculiarities of the diet, athletes cannot always consume a sufficient amount of potassium-rich food, the use of Asparkam is quite often the only way to compensate for the body's needs for this mineral element.

Against the background of the use of Asparkam, the heart rate decreases, and the pulse during exercise does not exceed the permissible value. In addition, K + and Mg2 + ions help to relax muscles, relieve excessive tension and cramps (the drug is often prescribed for leg cramps), and, therefore, the athlete can achieve better results during training.

As a result, the condition improves heart muscle , and also increases its productivity and readiness for high loads. All of these help to reduce risk. sudden death from cardiac arrest during intense exercise.

Many athletes take the drug in combination with .

Contraindications

The drug is contraindicated in:

• hypersensitivity to its constituent substances;
• OPN and chronic renal failure;
• oliguria , ;
• hypocorticism ;
• hypermagnesium or hyperkalemia ;
• acute metabolic acidosis ;
• cardiogenic shock (when systolic pressure does not exceed 90 mm Hg);
• atrioventricular blockade (AVB) II-III degree;
• severe ;
• dehydration .

Additional contraindications for parenteral use of the drug are children's age, severe liver failure , the risk of edema, metabolic acidosis .

With caution, Asparkam should be used in pregnant and lactating women, with urolithic diathesis (associated with impaired metabolism of ammonium phosphate, Ca2+ and Mg 2+), hypophosphatemia, AVB I degree.

Side effects

Side effects against the background of the use of Asparkam rarely develop.

When taking tablets, you can:

• disorders of the digestive system, which manifest as nausea, vomiting, diarrhea, burning sensation in the epigastric region, pain and discomfort in the abdomen, bleeding into the lumen of the stomach, small or large intestine, ulceration of the gastrointestinal mucosa, dry mouth;
• cardiovascular disorders , manifested in the form of a decrease in blood pressure, AVB, conduction disturbances myocardium ;
• violations by nervous system(usually this is paresthesia , convulsions, hyporeflexia );
• hypersensitivity reactions (itching, rash, redness of the skin of the face);
• symptoms hypermagnesemia (respiratory depression, fever).

With the rapid introduction of the solution into the vein, signs may occur Ghyperkalemia (paresthesia , diarrhea, nausea, vomiting) and/or hypermagnesemia (hyporeflexia , flushing of the face, feeling of heat, convulsions, respiratory depression).

Instructions for use Asparkam

Asparkam tablets: instructions for use

Asparkam tablets are taken orally after meals. Daily dose for an adult - 3-6 tablets. It should be divided into three doses.

The duration of the course depends on the nature and course of the disease.

Asparkam solution: instructions for use

The solution is intended exclusively for intravenous administration. With a drip infusion, 10-20 ml of Asparkam (the contents of 2-4 ampoules) are diluted in 50-200 ml of isotonic glucose solution. Infusion rate - 25 drops / min. The highest single dose of Asparkam is 20 ml. If necessary, the administration of the drug is repeated after 4-6 hours.

With a jet infusion, the infusion rate should not exceed 5 ml / min. The infusion solution is prepared by dissolving 10 ml of the drug in 20 ml of isotonic glucose solution or sterile water for injection.

The duration of the course is 5 days.

How to take Asparkam in tablets for athletes?

Athletes are advised to take the medicine three times a day, 1-2 tablets. Sometimes pills are drunk immediately before training (about an hour before it starts). single dose- 2-3 tablets. It is believed that in this way it is possible to compensate for the loss of potassium with sweat).

How to take Asparkam with Riboxin for the prevention of hypokalemia?

If Asparkam is used in combination with Riboxin , both drugs are drunk three times a day. Dosage of Asparkam - one tablet, Riboxina - two tablets for each dose.

The course of using each drug individually or in combination can be repeated every 90 days.

Instructions for the use of Asparkam for children: indications for use in pediatrics

In pediatrics, Asparkam is used to replenish potassium deficiency in children older than 12 months.

If, according to the results of a blood test for ions, it is diagnosed hypokalemia , then, regardless of the reasons that led to the development of this condition, Asparkam tablets are prescribed to the child.

Parenteral administration of the drug is allowed only in case of a threat to life.

Signs of hypokalemia in children are:

• drowsiness;
• lethargy;
• drop in blood pressure;
• arrhythmia ;
• muscle weakness.

In infants on hypokalemia may indicate increased gas formation in the intestinal lumen, poor suckling at the breast, dry skin, frequent regurgitation and/or vomiting.

Causes of hypokalemia in a child can be:

• diarrhea for at least 24 hours;
• repeated vomiting;
• severe liver/kidney pathology ;
• pathology of the digestive system;
• in / in the introduction of solutions of proteins, glucose, salts without potassium;
• the use of GCS;
• application non-potassium-sparing diuretics .

If the child has recently been exposed to the above factors hypokalemia , it is recommended to conduct a study of the electrolyte composition of the blood and determine the serum concentration of potassium.

If it turns out to be low or corresponds to the lower limit of the norm, the child is prescribed a course of treatment with Asparkam in an individual dosage.

IN pediatric practice the drug is also used to relieve arrhythmias caused by inflammatory myocardial injury , which developed as a complication of a bacterial or viral infection.

The dosage of Asparkam for children is selected depending on age. The course usually lasts from 7 to 14 days.

Children under the age of 12 months should be given ¼ tab./day. (the entire dose is taken at one time), children from one to 3 years old - ½ tab. / day, from 3 to 6 years old - ½ tab. twice a day, from 7 to 10 years - ½ tab. three times per day.

Dose for children 11-12 years old - 1 tab. once or twice a day, for children 13-16 years old - 1 tab. twice a day. From the age of sixteen, the drug is prescribed to take one tablet three times a day.

The indicated dosages are indicative. In each case, the treatment regimen is selected by the doctor, taking into account the characteristics of the child.

Children who take non-potassium-sparing diuretics or GCS, a doctor in addition to them in order to avoid the development hypokalemia also appoint Asparkam. Recommendations on how to take Furosemide with Asparkam or with Asparkam in one case or another, only the attending physician can give.

How to take Asparkam in combination with Diakarb?

The use of Asparkam allows you to compensate for side effects Diakarba , which, according to the instructions, can manifest as muscle weakness, a decrease in the concentration of K in the blood serum, the appearance of tinnitus, paresthesia , skin hyperemia, convulsions, metabolic acidosis , hematuria ,nephrolithiasis , hemolytic anemia , disorientation, , drowsiness, impaired sense of touch, leukopenia , allergic reactions .

By supplying cells with potassium and the energy necessary for their normal functioning, Asparkam reduces the increased alkalinity of the blood and minimizes the risk of developing severe adverse reactions.

Since at long-term use diuretic effect of Diakarba decreases rapidly, this remedy is prescribed to be taken in short courses (usually 2-4 days) at intervals of several days. Children under one year of age are given ¼ tablets / day. (a tablet is given to the child in the morning, before meals). Asparkam in the dosage recommended by the doctor (usually ¼ tab.) is given on the day of taking Diakarba.

Reviews of mothers and doctors indicate that treatment according to this scheme is the most effective way remove excess fluid from the body without complications. If necessary, it can be long.

How to drink the drug for a hangover?

Since alcohol contributes to the removal of fluid from the body, it, therefore, also removes the substances it needs at the same time. Particularly potassium and magnesium. Deficiency of Mg leads to saturation of the blood with calcium, and this, in turn, causes chills, increased nervous excitability, development of muscle weakness, and heart problems.

To eliminate the symptoms of a hangover, take 1-2 tablets of Asparkam after meals.

For the provision of drug treatment at home, the drug is justified to be used only in complex treatment. alcohol intoxication. As a remedy emergency care he doesn't matter.

Overdose

With an overdose of Asparkam, symptoms can theoretically develop hyperkalemia (diarrhea, nausea, metallic taste in the mouth, paresthesia of the limbs , abdominal pain, weakness, bradycardia ,muscular paralysis , disorientation) and symptoms hypermagnesemia (arterial hypotension , thirst, redness of the skin of the face, impaired neuromuscular transmission, hyporeflexia , arrhythmia , convulsions. respiratory depression).

On the ECG can be recorded:

• expansion of the ventricular complex;
• low P wave voltage;
• high voltage T wave.

If signs of an overdose appear, treatment with Asparkam is stopped, and the patient is prescribed an injection of a solution into a vein (dose - 100 mg / min) and - if necessary - (alternatively, it can be peritoneal dialysis ).

Interaction

Use in combination with an ACE inhibitor potassium-sparing diuretics , And beta-blockers may lead to the development hyperkalemia and strengthening the inhibitory effect on the contractile activity of the intestine.

Asparkam slows down absorption oral medications tetracyclines , sodium fluoride and iron salts (between doses of the indicated medicines three hours must be observed).

Potentiates the effects of drugs that stimulate trophic processes in the heart muscle ; prevents development hypokalemia against the background of the use of GCS, saluretics , cardiac glycosides ; reduces the severity cardiotoxic effects of cardiac glycosides .

In combination with peripherally acting muscle relaxants (Dexamethonium , Atracurium , Suxamethonium ) there is an increase in neuromuscular blockade, with general anesthetics ( , , Hexanal and etc.) - oppressed by the central nervous system .

Mg preparations reduce effectiveness Polymyxin B , , And Tetracycline . Asparkam in combination with Calcitriol promotes an increase in the serum concentration of Mg, in combination with calcium preparations, a decrease in the action of Mg ions is noted.

Information about incompatibility for injection form the drug is not available.

Terms of sale

Asparkam tablets are an over-the-counter drug. To purchase an injectable form of the drug, you must present a prescription issued by a doctor.

Sample recipe in Latin:

Rep.: Tab. Asparkam N. 50

D.S. 1-2 tablets 3 times a day.

Storage conditions

The optimum temperature for storing tablets and solution is up to 25 ° C (lower limit temperature regime storage for the solution - 15 ° C). Tablets should be protected from moisture, the solution - from exposure to light sources.

Best before date

Tablets are suitable for use within three years, solution for and - within two years after the date of issue.

special instructions

In patients receiving the drug for a long time, it is necessary to monitor ECG data, as well as indicators of serum concentrations of K and Mg.

The rapid intravenous administration of the parenteral form of the drug is contraindicated, since this can provoke the development hyperkalium- And hypermagnesemia and, consequently, to life-threatening patient arrhythmias .

With rapid introduction into a vein, skin hyperemia may develop.

Analogues

Coincidence in the ATX code of the 4th level:

Asparkam's analogs are drugs Aspangin , Asparkam-L , Potassium and magnesium asparaginate Berlin-Chemie , Potassium and magnesium asparaginate , Asparkam-Verrein , Asparkam-UBF , , Panangin Forte .

What is better Asparkam or Panangin?

Panangin like Asparkam, it is a preparation of potassium and magnesium. In one tablet Panangina contains 140 mg of anhydrous aspartate Mg and 158 mg of anhydrous aspartate K. The concentration of K + in 1 ml of the solution is 10.33 mg, Mg2 + - 3.37 mg.

That is, the differences between Panangin and Asparkam, which may affect the choice of a particular drug, are:

• dosage of active and composition of auxiliary components;
• release form (Panangin tablets are coated, which facilitates them and also prevents damage to tooth enamel.);
• price ( Panangin is a more expensive analogue of Asparkam; manufactured by Gedeon Richter).

Every year everything more people suffer from cardiovascular disease. And many of them doctors prescribe the drug "Asparkam". Why it is needed, not everyone understands, because it is believed that such a cheap medicine containing only potassium and magnesium cannot have a serious effect. But actually it is not. Potassium and magnesium ions are necessary for the normal functioning of the body. True, even cheap and seemingly harmless drugs are not recommended to be taken without a doctor's prescription. Therefore, you need to know what "Asparkam" is for, so that the use of this drug will only benefit the patient.

Why potassium and magnesium

These two elements are very important for the work of the heart. Moreover, potassium is considered the most effective, and magnesium mainly acts as a conductor of its ions into the cell. A sufficient amount of these elements in the body provides:

Correct conduction of the heart impulse;

Good contractile function of myocardial muscles;

Elasticity of the walls of blood vessels;

adjustment metabolic processes in the heart muscle

Decrease in blood viscosity.

Why is there a lack of potassium in the body?

Not everyone knows why Asparkam is prescribed. And this is done mainly for patients who have a lack of potassium ions. Why can this happen?

Even with proper nutrition trace elements enter the body with food in very small quantities;

A lot of potassium and magnesium are lost with heavy sweating in hot weather and with increased physical activity;

The absorption of microelements is disturbed in case of hormonal failures, diabetes or metabolic diseases;

Gastrointestinal diseases, such as gastritis or pancreatitis, also lead to impaired potassium absorption;

Losses of these necessary elements often occur with indigestion and intestinal infections, especially accompanied by diarrhea;

Use of alcohol, caffeinated products, and certain medicines also contribute to excessive excretion of potassium. Therefore, in such conditions, the drug "Asparkam" is often prescribed. Why it is needed - it will become clear when you understand what threatens the lack of these trace elements.

What happens when there is a lack of potassium and magnesium

If a cell lacks one element, it is immediately replaced by another. In the case of potassium, it is sodium, which strongly binds water. As a result, the cell swells and cannot perform its functions normally. This is especially true for the work of the heart. His muscles cannot contract normally. Magnesium is replaced by calcium, an excess of which can lead to spasms. This prevents the heart muscle from relaxing and nutrients from entering it. In this case, the drug "Asparkam" helps. Why it is prescribed is understood by those who often experience such symptoms:

Spasms of muscles and blood vessels, convulsions, especially at night;

Violation of the heart rhythm;

Anxiety, increased irritability and a tendency to depression;

Violation of the gallbladder and kidneys, the formation of stones.

Why appoint "Asparkam"

1. Most often, this drug is used in the treatment of diseases of cardio-vascular system. It can be arrhythmia, angina pectoris or heart failure. Sometimes, together with some drugs, "Asparkam" is also prescribed. What is it for? Some medications can cause arrhythmias or irregular heartbeats, as well as promote excessive excretion of potassium.

2. To strengthen the nervous system, with nervousness, irritability and stress.

3. To normalize the functioning of the gallbladder and gastrointestinal tract.

4. In the complex treatment of certain diseases associated with a lack of potassium and magnesium.

5. When removing from hard drinking, treatment of alcoholism.

6. Why take "Asparkam" yet? In some conditions, there is a deficiency of potassium, for example, heavy sweating, stool disorders, or taking diuretic drugs. Recently, it is recommended to drink this drug while following diets for weight loss. It helps to compensate for micronutrient deficiencies and accelerates weight loss.

"Asparkam" for heart disease

Salts of potassium and magnesium are vital for the normal functioning of the heart muscle. Therefore, very many cores are prescribed Asparkam. Why it is needed is often not explained, so some patients take the drug lightly, believing that such a cheap medicine cannot have a serious effect. But in fact, "Asparkam" very effectively helps with such conditions:

With violations of the heart rhythm;

In the rehabilitation or prevention of myocardial infarction;

In violation of metabolic processes in myocardial cells;

With angina pectoris and coronary heart disease, they also drink Asparkam.

Why is this drug used in complex treatment? It is effective in various vascular pathologies, such as epilepsy, glaucoma, or simply circulatory failure.

With what drugs you need to drink "Asparkam"

Why is this drug needed in the treatment of certain drugs? It helps to reduce their side effects, such as lack of potassium salts or heart rhythm disturbances. Together with what means, the drug "Asparkam" is still required to be prescribed:

Why should you drink it together with Diakarb? This decongestant actively removes sodium and potassium ions from the body, and Asparkam is needed to make up for its deficiency.

If it is necessary to take the drug Furosemide, doctors must prescribe Asparkam tablets with it. What is it for? "Furosemide" is a strong diuretic and contributes to the rapid loss of potassium by the body. This can lead to heart failure and arrhythmias.

Very often, together with cardiac glycosides, the medicine "Asparkam" is prescribed. Why do they do it? Glycosides are herbal preparations used to treat heart disease. But with prolonged use, they often slow down the heart rate and can cause arrhythmia. To prevent these complications, "Asparkam" is used.

Contraindications to taking the drug

This cheap and effective medicine can not be drunk by everyone. Especially serious contraindications to taking Asparkam are in diseases accompanied by fluid retention in the body and slow excretion of potassium. In this case, taking the drug can lead to an excessive accumulation of this trace element, which is also harmful to health. When you can not drink "Asparkam"?

With kidney dysfunction and insufficient urination;

In violation of the function of cardiac conduction;

RBC damage or acute blood acidosis;

In a state of shock, with severe myasthenia gravis or dehydration;

With severe metabolic disorders;

Allergic intolerance to the components of the drug.

Injections of the drug are contraindicated in low blood pressure and during pregnancy.

Can "Asparkam" cause side effects

This seemingly harmless drug in some cases can be dangerous to health. Some patients believe that it, like vitamins, can be taken at any time. But it is undesirable to drink "Asparkam" without a doctor's prescription. What this drug is used for and in what doses, only a specialist can know. You need to drink it only when the body really needs an additional introduction of potassium and magnesium. An overdose of these elements can lead to undesirable consequences. May develop:

Nausea, vomiting, dry mouth, ulcers, abdominal pain and stool disorders;

Violation of the heart rhythm, pressure surges, shortness of breath and dizziness;

Thirst, redness of the face, numbness of the extremities, skin itching;

Weakness, drowsiness, fatigue, low blood pressure.

The drug "Asparkam" and its analogues

Medicines containing potassium and magnesium are often prescribed to cores as part of complex therapy. But recently, doctors have begun to recommend more expensive analogues of Asparkam. Their differences often lie only in the manufacturer and price, but there are also different content of active ingredients. Therefore, the question of the advisability of replacing the drug can only be decided by a doctor. Although many "experienced" patients trust Asparkam more, it is also the cheapest of the drugs in this group: a pack of 50 tablets can be purchased for only 20-50 rubles.

More expensive medicine is Panangin. Its composition is similar, although the active substance is contained in a lower dosage, so the drug is considered safer. This is a foreign-made medicine and costs about 150 rubles per pack. Less well known is a drug called Potassium and Magnesium Aspartate. They are produced by different pharmaceutical companies, and their price depends on this.

Good day, dear friends! Do you know what Asparkam is used for? It turns out that this is a pretty useful drug.

Often it is prescribed along with other medicines to reduce intracranial pressure.
Doctors were also interested sports medicine. Asparkam is excellently perceived by the body and excreted.

It contains useful components that are indispensable for heart problems. Let's find out more information about this drug.

You can buy Asparkam in the form of tablets flat shape or solution for injection in ampoules of 5 and 10 ml.

It contains only two active ingredients:

1. Potassium, which provides nerve impulses, has a diuretic effect and reduces muscles.
2. Magnesium is involved in enzymatic reactions, in the movement of ions, as well as in cell growth processes.

The tablets contain 175 mg of each of the components. In addition, the composition contains corn starch, polysorbate-80, talc and calcium stearate.

The principle of action of the drug is based on the ability of magnesium and potassium ions to penetrate and participate in metabolism.
The dosage of the drug depends on the age, symptoms of the disease and the course of treatment. Most often it is determined by a doctor.

The medicine is also used for children. In this case, the drug is prescribed from the age of three. You can not self-medicate and prescribe it yourself, especially for a child.

There is different forms drug, such as Asparkam Avexima.

Asparkam properties

Let's find out more information about the properties of the drug, and for what diseases it is taken. Asparkam is effective in many diseases.

Potassium and magnesium ions allow you to restore the work of the heart after myocardial infarction. It is also prescribed in combination with other components to stimulate cardiac activity.
Potassium in the composition of the drug helps:

• muscle contractions;
• normalization of the work of the heart;
• decrease in myocardial excitability;
• expansion of the coronary arteries;
• passage through the fibers of nerve impulses.

Magnesium is involved in various enzymatic processes, and also takes part in the synthesis of essential acids and cell division.
The drug is prescribed for coronary disease heart, glaucoma and high intracranial pressure.

It is shown to improve metabolic processes and increase muscle mass. Therefore, it is often used in bodybuilding.

Who is shown

According to numerous reviews, it is taken with a lack of magnesium and potassium in the body.
Let's find out what the medicine has indications for use:

1. Violation of metabolic processes.
2. Magnesium and potassium deficiency after significant fluid loss. This happens with diarrhea severe vomiting, prolonged dehydration, excessive sweating.
3. Long periods of use of diuretic and laxative drugs. Asparkam is often prescribed along with a drug such as Furosemide, which removes potassium from the body.
4. Cardiac problems, including angina pectoris, arrhythmia, pre-infarction conditions, heart failure.
5. shock states.
6. Appearances.
7. Urolithiasis. It is used even for dissolution.
8. Protects against complications that may occur after prolonged use of glycosides.
9. Pathologies such as glaucoma, gout and inner ear disease.

For the prevention of stroke, the drug is prescribed simultaneously with the drug Diakarb.

Why appoint athletes

It is not uncommon for Asparkam to be used by athletes, although it does not particularly accelerate the formation of muscle cells and tissues.

It is interesting to know, then why is he?
When gaining weight, athletes consume a large amount of high-calorie foods and proteins, but very little attention is paid to foods containing potassium.
For active people, the benefits of the drug are as follows:

1. Reduces the feeling of fatigue.
2. Replenishes the lack of potassium and magnesium in the body.
3. Eliminates muscle weakness.
4. Stabilizes the work of the heart.
5. Prevention of stroke and angina.
6. Helps with.

Depending on the training of athletes, the doctor prescribes the course of the drug. In addition to prevention, Asparkam is used during periods of intense training.

How to apply

So that the pills do not harm, follow the instructions and follow all the recommendations of the doctor. How to drink the medicine depends on the specific diagnosis.

If the drug is prescribed only for preventive purposes then the dosage should be halved. Most often this is a tablet three times a day. The course of prevention lasts about a month.

With illness, the course can last a week. Reception is resumed after consulting a doctor.
The drug is also taken intramuscularly and intravenously, but only as directed by a specialist.
Used for injection 30 ml drugs that are diluted with glucose solution and saline. Dosage for an adult varies within 10-20 ml.
Intravenous procedures are performed only by medical professionals.
With long-term use of drugs, it is important to control the content active components in organism.

An electrocardiogram should also be performed periodically.

Trace elements at complex application normalize water - salt balance in the body, which helps to cope with swelling.

At the same time, weight may decrease, but this is only due to getting rid of excess water.
In general, follow these rules:

• the price of the drug is small, but the appointment is carried out by a doctor, as this is an individual process;
• with long-term use, it is necessary to control substances in the blood plasma;
• intravenous injections require precautions. First of all, the drug should not have turbidity. After opening, apply immediately. It must be administered immediately to avoid overdose.

Side effects

If the medicine is administered by injection, then there is a risk of overdose.

They are manifested by such symptoms:

1. Redness and swelling of the skin.
2. Thirst.
3. Rapid breathing.
4. Seizures.
5. In rare cases, coma.

In such situations, it is important to immediately stop taking the medicine. Then calcium gluconate is administered intravenously.

If the cases are severe, then blood purifications are carried out.

What are the contraindications

Now let's deal with contraindications.

Here they are:

1. Individual intolerance.
2. Kidney problems.
3. Excess potassium.
4. excess magnesium.
5. Pathologies of metabolic processes.
6. Problems with the genitourinary system.
7. Co-administration with diuretics.
8. Rarely given to children. Especially breastfeeding.
9. Not recommended for pregnant women and women.

During the course of treatment, it is impossible, which will adversely affect the functioning of the kidneys. There are certain restrictions for the elderly.

Interaction with other drugs

The drug is combined with glycosides, as this reduces the outflow of potassium from the blood, which reduces the toxicity of drugs.

Glycosides are prescribed for elevated heart rhythms.
If taken along with Cyclosporine, that is, the risk of an excess of potassium in the body. streptomycin and neomycin lose their effect when combined with this remedy.
Do not use with potassium-sparing tablets.
In some cases, it is prescribed together with diuretic drugs.

Features of the appointment for children

For young children, the drug is prescribed when diagnosing a lack of potassium. For example, with hopokalemia.

IN childhood administered only in the form of tablets.

Potassium deficiency in children's body manifests itself in the form of muscle flaccidity, weakness, decreased pressure and arrhythmia.

Infants may have a sluggish appetite, spit up frequently, and dry skin.
In childhood, hypokalemia can occur with prolonged vomiting, treatment with glucocorticosteroids, liver and soil diseases, and also with gastric pathologies.
If there were such factors, then a special blood test is performed. With a lack of potassium, the course of treatment may be 1-2 weeks.

The dosage is determined by the doctor.

It can also be prescribed for arrhythmia, which appears after viral and bacterial infections.

Any useful trace elements and can cause great harm to the body with uncontrolled use.

It is better to choose a place inaccessible to children, which is well protected from moisture and light. Only when correct application can deal with certain problems.
If you liked the article - share useful information with your friends.

Subscribe to my blog updates to receive only the latest news. See you soon, friends.

Producer: Arterium (Arterium) Ukraine

ATC code: A12CC55

Farm group:

Release form: Solid dosage forms. Tablets.

General characteristics. Composition:

Active ingredients: 1 tablet contains magnesium aspartate 175 mg (0.175 g), potassium aspartate 175 mg (0.175 g);

excipients: corn starch, polysorbate-80, calcium stearate, talc.

Description. Tablets of white color, with a smooth surface, ploskotsilindrichesky, with risk, with a specific smell. Marbling is allowed on the surface of the tablets.

Pharmacological properties:

Asparkam refers to drugs that regulate metabolic processes. The mechanism of action is associated with the role of asparaginates to carry magnesium and potassium ions into the intracellular space and their participation in metabolic processes. Asparkam eliminates electrolyte imbalance, magnesium and potassium deficiency, reduces myocardial excitability and conductivity, exhibits a moderate antiarrhythmic effect, improves myocardial metabolism and coronary circulation, and also reduces myocardial sensitivity to cardiac glycosides and their toxicity. Mg2+ ions activate Na+, K+-ATPase. In this connection, the intracellular concentration of Na + ions decreases and the flow of K + ions into cells increases. With a decrease in the concentration of Na + ions inside the cell, the exchange of Na + and Ca2 + ions in the smooth muscles of the vessels is inhibited, which leads to their relaxation. K+ ions stimulate the synthesis of ATP, glycogen, proteins, acetylcholine. K+ and Mg2+ ions maintain the polarization of cell membranes. Asparaginate is a carrier of K+ and Mg2+ ions and promotes their entry into the intracellular space. Once in the cell, aspartate is also included in the metabolic processes, promotes the synthesis of amino acids, amino sugars, nucleotides, nitrogen-containing lipids, and corrects the violation of the energy metabolism of the ischemic myocardium.

Rapidly and completely absorbed, excreted mainly by the kidneys. The concentration of potassium and magnesium in the blood reaches a maximum 1-2 hours after taking the drug. From the blood, the drug enters the inside of cardiomyocytes in the form of K+, Mg2+, and asparaginate ions and is included in cellular metabolism.

Indications for use:

As part of complex therapy, conditions after myocardial infarction, cardiac arrhythmias (mainly ventricular arrhythmias) caused by electrolyte disturbances;
to enhance the effectiveness and improve the tolerability of cardiac glycosides;
in conditions accompanied by hypokalemia and hypomagnesemia (including overdose of saluretics).

Dosage and administration:

Asparkam tablets are taken orally.

For adults, the drug is prescribed 1-2 tablets 3 times a day after meals.

The course of treatment is determined by the doctor depending on the nature and course of the disease.

Application Features:

Appropriate safety precautions for use. With prolonged use of the drug, it is necessary to control the level of potassium and magnesium in the blood, and regular monitoring of electrolyte hemostasis and ECG data is also necessary.

Use during pregnancy or lactation. Data on the negative effects of the drug during pregnancy or lactation are not available. The use of the drug is possible if, in the opinion of the doctor, the expected benefit to the mother outweighs the risk to the fetus or child.

The ability to influence the reaction rate when driving vehicles or working with other mechanisms. Asparkam does not affect the reaction rate when driving vehicles or working with other mechanisms.

Children. There is no experience of using the drug in children.

Side effects:

Adverse reactions develop very rarely
from the digestive tract: abdominal pain, discomfort or burning sensation in the epigastric region, gastrointestinal, ulcers of the mucous membrane of the digestive tract, dry mouth;
on the part of the cardiovascular system: myocardial conduction disturbance, lowering blood pressure, AV blockade;
from the side of the central and peripheral nervous system:, hyporeflexia,;
allergic reactions: itching, redness of the skin of the face, rash;
from the respiratory system: respiratory depression is possible (due to hypermagnesemia);
others: feeling of heat.

Interaction with other drugs:

Due to the presence of potassium ions in the preparation, when using Asparkam with potassium-sparing diuretics, ACE inhibitors, beta-blockers, cyclosporine, the risk of developing hyperkalemia increases (it is necessary to control the level of potassium in the blood plasma) and the inhibitory effect on intestinal motility increases.

The drug inhibits the absorption of oral forms of tetracycline, iron salts and sodium fluoride (it is necessary to adhere to a three-hour interval between doses).

Asparkam enhances the effect of drugs that stimulate trophic processes in the myocardium; prevents the development of hypokalemia due to the use of saluretics, corticosteroids, cardiac glycosides. Asparkam reduces the cardiotoxic effect of cardiac glycosides.

With simultaneous use with antidepolarizing muscle relaxants, neuromuscular blockade is enhanced, with anesthetic agents (ketamine, hexanal, halothane, etc.), the central nervous system is inhibited.

Asparkam may reduce the effectiveness of neomycin, polymyxin B, tetracycline and streptomycin.

Contraindications:

Hypersensitivity to the components of the drug;
acute and arrhythmia, convulsions). On the electrocardiogram, an increase in the height of the T wave, a decrease in the amplitude of the P wave, and an expansion of the QRS complex are recorded.

Treatment: drug withdrawal, symptomatic therapy ( intravenous administration calcium chloride solution at a dose of 100 mg / min), if necessary -.

Storage conditions:

Shelf life 3 years. Store in a dry place at a temperature not exceeding 25 °C. Keep out of the reach of children.

Leave conditions:

Without recipe

Package:

50 tablets in a blister; 50 tablets in a blister, 1 blister in a pack.