One of the main symptoms of the dysfunction of the tract is pain. Provokes pain in the intestines, as a rule, spasm. In addition, in gynecology, with the pathology of urinary tract and other painful manifestations of smooth muscles related to the relief of these states, Motropic spasmolitis has been developed.

What spasmolytic is better?

Preparations have side effects and contraindications

DROTAVERIN

It differs from papaverin longer and strong action. It is used in the case of contraindications to cholin bockers. Reduces intestinal peristalsis, muscle tone, extends vessels. Does not penetrate the brain. Has high bioavailability. Contraindications: Increased sensitivity, cardiogenic shock, hypotension, cardiac, renal and liver failure. Caution with pregnancy and lactation, glaucoma, atherosclerosis coronary arteries. Side effects: hypotension, headache, insomnia, tachycardia, constipation, nausea. Advantages - Low price.

Available under the names of DROTAVERIN (45 rubles per 20 tab.), (More expensive - 132 rubles), spasmod, spasier

"DROTAVERIN" 50 Tablets of Russian production
"But-shp" 24 tablets

Papaverin hydrochloride

Reduces the tone of muscles of organs and vessels. Increases blood flow, including in the brain. In large doses, a sedative effect, a decrease in cardiac excitability and conductivity. It is used to remove muscle spasms and as premedication. Produced in the form of tablets (the price of 40 rubles), candles, injection mortar (10 rubles per ampule).

Mebavserin

Reduces the reduction in smooth muscles and their tone. Assign for. Side effects (less compared to doll and papaverine): dizziness, allergies, nausea, diarrhea. Contraindicated in pregnancy. Refrain from activities requiring concentration of attention during treatment.

Hyoscin Butyl bromide

Violates the transfer nerve impulses In smooth muscle cells. In addition to the basic effect, normalizes (reduces) secretion digestive glands. Does not work on the CNS. Eliminates pain and discomfort in the stomach. Contraindications: Clothing glaucoma, pregnancy, pulmonary swelling, Miastic, atherosclerosis of the brain vessels. Carefully in the first trimester of pregnancy. Maximum concentration of the drug after 2 hours. To achieve the effect requires small doses. Does not have an atropine-like action. The minimum probability of side effects (less than that of no-shops): tachycardia, shortness of breath, urine delay, dry skin, dry mouth.

Trade name - Buscopan: Tablets (315 rubles) and rectal candles (377 rubles).

Spasmalgon

The combined drug, which contains: sodium metamizole (NSAID with an analgesic, anti-inflammatory, antipirelic property), Pitophenone hydrochloride (similar to the action with papaverine), bromide phenpymerinium (relaxes muscles, M-cholinoblocator). Active substances enhance each other. Contraindications: angina, hsn, pregnancy and lactation, up to 6 years, intestinal obstruction, high sensitivity. During the treatment period, control the content of leukocytes and the function of the liver, eliminate alcohol, controlling motor vehicles. Release form: Tablets (from 136 rubles), ampoules (32 rubles per 1 pc.).

Combined agent. Contains an alveherine - an antispasmodic of myotropic action, Simethikon - reduces gas formation. Indications: Distribution of the GTS, Preparing for Research abdominal cavity (UZ, instrumental, radiological). Cost of capsules 416 rubles.

Expruit funds in tableted forms are easy to have with you, they are easy to use in the necessary situation.

Akabel (Akabel)

Combined drug containing an antispasmodic (means of removing spasms) Bevonium methyl sulfate and nonarcotic analgine analgine.

Pharmachologic effect. It has bronchoves and antispasmodic properties (expanding the lumen of the bronchi and removes spasms).

Indications for use. Bronchial asthma, bronchospasty syndrome (narrowing of the lumen of bronchi), ulcerative disease Stomach and duodenum, Pylorospasm (spasm muscle gatekeeper stomach), postoperative spastic pain, spastic constipation, cholestasis (stagnation of bile), cholangitis (inflammation of bile ducts), postcholecovectomic syndrome (condition after the operation to remove the gallbladder), chronic hepatopathy (general name Liver diseases) and pancreatitis (inflammation of the pancreas), various diseases of the kidneys and urinary tract. Prenatal and postpartum pains, dysmenorrhea (menstrual cycle disorder), adnexite (inflammation of the appendages of the uterus), endometritis (inflammation of the inner surface of the uterus), dysfunction of ovarian, tumor of genitalia (genital organs).

Method of use and dose. Akabel is prescribed inside 1-2 tablets 2-3 times a day, candles (adult only) - 1 candle 2-3 times a day. Intramuscularly or intravenously slowly introduced on L / I- Akabel 3 times a day.

Side effect. With intramuscular administration of the drug is possible transient local pain. Long-term use causes dryness in the mouth, the increase in the pulse, difficulty urination, the expansion of pupils.

Contraindications. Glaucoma (elevated intraocular pressure), tachycardia (rapid heartbeat), adenoma (benign tumor) of prostate, organic stenosis (narrowing of the lumen) gastrointestinal tract, Megolon (significant expansion of a part or all the colon), antidepressant therapy. Allergies to the pyrazolone derivative, with granulocyptopenia (decrease in blood granulocytes). Subcutaneous and intraarterial administration of the drug, as well as applications during pregnancy, especially in the first 3 months should be avoided.

Release form. Tablets containing the bevonyum of methyl sulfate 0.05 g, analgin 0.25 g; Candles containing

methyl sulfate bevonyum 0.03 g, Analgin 1 g; 5 ml ampoules containing mixtures of methyl sulfate 0.0025 g, Analgin 2.5 g

Storage conditions.

Alprostadil (Alprostadil)

Synonyms: Vaison, Prostavazin, Minsk, Prostandin, Prostann BP.

Pharmachologic effect. Preparation from the Prostaglandin Group (Prostaglandin EI). It causes a reduction in the muscles of the uterus, intestines and other smooth muscle organs, but at the same time has a pronounced peripheral vasodilating effect, increases blood flow in peripheral vessels, improves microcirculation, slows down the aggregation (gluing) platelets and has a disaggregation effect.

Indications for use. It is used mainly in chronic binding diseases of the lower extremities (inflammation of the inner shell of the arteries of the limbs with a decrease in their lumen / oblique atherosclerosis, etc. The drug is more effective in II-III stage of ischemia (insufficient blood supply) of the lower extremities.

Method of use and dose. Alprostadil is used intravenously and intraarterially.

For intravenous use, the contents of 2 ampoules (40 μg of the drug) are diluted in 250 ml of isotonic sodium chloride solution. Drip (for 2 hours) is introduced 1 time, in severe cases 2 times a day. If there is such a need, the dose increases to 60 μg (3 ampoules) and administered for 3 hours.

In case of intraarterial administration, 20 μg (1 ampule) in 50 ml of isotonic sodium chloride solution is diluted. Initially, 10 μg ("/ 2 ampoules, i.e. 25 ml) are introduced (" / 2 ampoules) within 60-120 minutes; with good tolerability, in the future, it is possible to introduce 40 μg (for the same time). Injections produce 1-2 times a day. Long infusion is possible through the catheter.

The course of treatment lasts 15-25 days.

Side effect. When using alprostadyl, it is possible to reduce blood pressure, loss of appetite, diarrhea (diarrhea), stupid pain in the limb exposed to treatment, a feeling of burning, redness at the point of introducing a catheter.

Contraindications. The drug is contraindicated in pregnancy and breastfeeding. It should be borne in mind that

alprostadil enhances the effect of hypotensive (reduced blood pressure) and anti-aggregation (prevent platelet bonding).

Release form. In ampoules containing 0.02 mg (20 μg) alprostadyl, 10 pieces per pack.

Storage conditions. List of B. in light-protected place when room temperature.

Andecalin (Andecalinum)

Purified pancreatic extract pig breast, not containing insulin.

Pharmachologic effect. Expanding peripheral blood vessels, reduces blood pressure.

Indications for use. Supporting endarterite (inflammation of the inner shell of the limbs with a decrease in their lumen), Reino disease (narrowing of the lumen of the limb vessels), sluggishly healing wounds, spasms (sharp narrowing of the lumen) of the brain vessels, circulatory disruption in the retina, sclerodermia, the initial stages of hypertensive disease ( persistent increase in blood pressure).

Method of use and dose. Intramuscularly 1 time per day 10-40 units (depending on the severity of the state) within 2-4 weeks; After a 2-3-month break, the course of treatment is repeated. Inside food 2 tablets 3 times a day. After 6-10 days, the dose can be increased gradually up to 9-12 tablets per day. The duration of the course of treatment 1 month. After a 2-3 month break, the course of treatment can be repeated.

Side effect. Allergic reactions.

Contraindications. Increased intracranial pressure, malignant neoplasms.

Release form. Lyophilized (dried by freezing under vacuum) anhekalin for injection in bottles of 40 units complete with solvent for injection; Tablets 15 pieces covered with shell, in packing 50 pieces.

Storage conditions. The preparation in a dry (lyophilized form) is preserved in a dry place at a temperature not higher than +18 ° C. In a dissolved form, it can be stored in a bottle not longer than 3 days at a temperature of +5 ° C; Tablets - in a dry place at a temperature not higher than +20 ° C.

BARALGIN (BARALGINUM)

Synonyms: Maksigan, Spasmalgon, Trigan, Spasgan.

Combined drug containing analgine nonarcotic analgesic, spasmolytic (means removing spasms), close to papaverine, and gangliplocator.

Pharmachologic effect. It has pronounced antispasmodic (removable spasms) and an painful effect.

Indications for use. Smooth muscles, especially renal colic, ureteral spasms, bladder tensions (false painful urination, liver colic, stomach and intestinal spasms, spastic dysmenorrhea (general name of the menstrual cycle disorders leaking with pain syndrome).

Method of use and dose. Inside 1-2 tablets 3 times a day, in severe cases - intramuscularly or intravenously slowly.

Side effect. Allergic reactions are possible, when long use Granulocyptopenia (decrease in blood granulocytes) requires the cancellation of the drug.

Contraindications. Granulocyptopenia (decrease in blood granulocytes), Tahiaritimia (view

violations of the rhythm of heart abbreviations), the insufficiency of the coronary (heart) blood circulation, glaucoma (increased intraocular pressure), hypertrophy (increase in volume) of the prostate.

Release form. Pills in the package of 20 pieces; Ampoules 5 ml per pack of 5 pieces.

Storage conditions. List B. in a dry, light-protected place.

Hawthorn Fruits and Flowers (Fructus Et Flores Crataegi)

Pharmachologic effect. Hawthorn preparations reinforce the reduction of the heart muscle and reduce its excitability, improve blood circulation in the heart and brain vessels, increase the sensitivity of the heart to the action of cardiac glycosides.

Indications for use. Functional disorders of cardiac activity, hypertensive disease (resistant blood pressure), angiogenesis (violation vascular tone), flickering arrhythmia, paroxysmal tachycardia (violation of the heart rhythm).

Method of use and dose. Inside 30 minutes before meals in the form of infusion (1 teaspoon on a glass of boiling water) - 1 tablespoon 2-3 times a day, tincture - 20 drops 3 times a day, liquid extract - 20-30 drops 3-4 times a day.

Release form. Fruits in packing 50 g; tincture in bottles of 25 ml; liquid extract in 25 ml bottles; Flowers in the package for 100 g.

Storage conditions. In a dry, cool place.

Hawthorn extract is also included in the carcardine preparations, cardiovalen.

Halidor (Halidor)

Synonyms: Beziklan Fumarat, Bencyclamide.

Pharmachologic effect. Antispasmodic (removable spasms) and vasodilator.

Indications for use. ENDARTERIT (inflammation of the inner shell of arteries), Trombalgitiite (inflammation of the arteries wall with their blockage), spasms (sharp narrowing of the lumen) of the vascular of the brain and coronary vessels (heart vessels), ulcerative disease, urinary tract spasms, cholecystitis (gallbladder inflammation).

Method of use and dose. Inside of 0.05-0.1 g 2-4 times a day, intramuscularly (if necessary intravenously), 1-2 ml of 2.5% solution. Course of treatment 15-20 days. With refrovered diseases of the arteries of the limbs (inflammation of the inner shell of the arteries of the limbs with a decrease in their lumen), treatment is effective mainly in the stage II of the disease; injected intramuscularly (0.05 g 1-2 times a day for 15-20 days).

Side effect. Disps (digestion dispersion), allergic reactions, dizziness, headache.

Contraindications. Pronounced disorders of blood circulation and breathing.

Release form. Tablets 0.1 g per pack of 50 pieces; Ampoules 2 ml of 2.5% solution per pack of 10 pieces.

Storage conditions. List B. in a dry, light-protected place.

Gangleron (Gangleronum)

Synonyms: Ganglefen hydrochloride.

Pharmachologic effect. Blocks n-cholinoreactive systems of parasympathetic and sympathetic vegetative ganglia and the central nervous system.

it has a myotropic antispasmodic (removable spasms of smooth muscles), a weak local excrement and anesthetic effect.

Indications for use. Stenzard, ulcerative disease of the stomach and duodenum, spastic dyskinesia (violation of mobility) of the gastrointestinal tract, etc.

Method of use and dose. Inside 0.04 g 3-4 times a day before meals; Intramuscularly or subcutaneously 1 ml of 1.5% solution 3-4 times a day with a gradual increase in one-time dose to 3 ml. Higher motherwise dose For adults inside - 0.075 g, daily - 0.3 g, the highest one-time dose is subcutaneously and intramuscularly -4 ml of 1.5% solution, daily - 12 ml of 1.5% solution.

Side effect. Dizziness; If you get on the mucous membranes, a quickly passing feeling of irritation with subsequent anesthesia.

Release form. Capsules of 0.04 g per pack of 50 pieces; Ampoules 2 ml of 1.5% solution per pack of 10 pieces.

Storage conditions. List B. in a dry, light-protected place.

Datiscan (Datiscanum)

It is a mixture of flavonoids, the main component of which is the glycoside of datiscin. Get from the grass of the datozya hemp.

Pharmachologic effect. Antispasmodic (means relieving spasms).

Indications for use. Diseases of the gastrointestinal tract accompanied by a spasm of smooth muscles (vessel muscles and internal organs).

Method of use and dose. Inside 15 minutes before the meal of 0.05-0.1 g 2-3 times a day daily for 10-20 days.

Side effect. Allergic reactions, headache, nausea, pain in the stomach, diarrhea.

Contraindications. Individual intolerance to the drug.

Release form. Tablets at 0.05 g per pack of 50 pieces.

Storage conditions. In a dry, protected from light place.

Dibazol (Dibazolum)

Synonyms: Bendazole, Bendazole Hydrochloride, Tromazedan.

Pharmachologic effect. Vasodinating, antispasmodic (removable spasms) and hypotensive (reduced blood pressure).

Indications for use. Diseases accompanied by spasms blood vessels (angina, hypertensive crisis / fast and sharp rise of blood pressure /), smooth muscles of internal organs (ulcer disease, spasms of the gastrointestinal tract), treatment of nervous diseases, mainly residual phenomena of polio, peripheral paralysis of the facial nerve, etc.

Method of use and dose. Inside take 0.02-0.05 g 2-3 times a day usually for 3-4 weeks. or shorter courses. In the treatment of nerve diseases, dibazole is prescribed from 5 to 10 times at a dose of 0.005 g (adults) one time per day or every other day. After 3-4 weeks. The course of treatment is repeated. Subsequent courses are carried out with a break of 1-2 months. Higher doses for adults inside: one-time - 0.05 g, daily - 0.15 g. Children are prescribed (in the treatment of diseases of the nervous system) in the following doses: up to 1 year - 0.001 g, 1-3 years 0.002 g, 4-8 years - 0.003 g, 9-12 years old - 0.004 g, older than 12 years -

0.005, if necessary, the course of treatment is repeated after 3-4 weeks. Dibazole is taken inside 2 hours before meals or 2 hours after meals.

Side effect. Dibazole is usually well tolerated. The drug is inappropriate to prescribe a long time as a hypotensive agent of elderly patients, since the hypotensive effect is associated with a decrease. heart Emission And it is possible to deteriorate the indicators of the electrocardiogram.

Release form. Tablets at 0.02; 0.002; 0.003 and 0.004 g; 0.5% or 1% solution in ampoules of 1; 2 and 5 ml.

Storage conditions. List B. in a dry, light-protected place.

Dilminal (Dilminal)

Synonyms: Dilminal-d.

Pharmachologic effect. Expands blood vessels.

Indications for use. Diseases of peripheral vessels and associated trophic violations: spastic forms of endarterity (inflammation of the inner shell of the arteries of limbs with a decrease in their lumen), Reino disease (narrowing of the lumen of the limbs), sluggishly healing wounds and ulcers.

Method of use and dose. With light shapes of the disease begin with 2 dragees 3 times a day. Dose is selected individually. With more severe forms, deep intramuscularly 1 ampoule 1 time per day. The drug is dissolved immediately before use. Course of treatment 15-20 injections.

Side effects and contraindications are the same as for Andekalin.

Release form. Dragee 2 units per pack of 20 pieces; Ampoules (Dshshina D) containing 10 units with a solvent application, in a package of 10 pieces.

Storage conditions.

Diprofen (Diprophenum)

Pharmachologic effect. It has a vasodilatory and weak cholinolithic effect.

Indications for use. Spasms (involuntary muscle contractions) of blood (especially peripheral) vessels (endarterite / inflammation of the inner shell of the artery /, Reino disease / narrowing of the lumen of the vascular vessels / etc.), smooth muscles of internal organs (bronchi, gastrointestinal tract, urinary tract).

Method of use and dose. Inside 0.025 g 2 times a day with a gradual increase in dose to 0.05-0.1 g 3 times a day. Course of treatment - 2-3 weeks.

Side effect. Feeling numbness of the oral mucosa, occasionally nausea, headache, light dizziness.

Release form. Tablets at 0.05 g per pack of 10 pieces.

Storage conditions. List B. in a well-unpaved container.

Diprophyllinum (Diprophyllinum)

Synonyms: Aristophyllin, Diffylin, Isophillery, Astrofellin, Coronal, Coronary, Corfillamin-Nettral, Diprophylline, Gulifillain, Neutrafillin, Solofillain, Tefilan, Theofen, etc.

Pharmachologic effect. It has a coronary-eyed (expanding heart vessels) and the bronchophustic (expanding lumen of the bronchi) action, somewhat increases diuresis (uriction volume).

Indications for use. Coronaropasm (narrowing of the lumen of the blood vessels), bronchospasm (narrowing of the lumen of bronchi), arterial hypertension (resistant blood pressure), hypertensive disease.

Method of use and dose. Prescribed inside, intravenously, intramuscularly. Intravenously introduced (slowly!) 5-10 ml (adult) 2.5% solution (diluted in aseptic / sterile / 1 ampule / 5 ml / 10% solution in 15 ml of water for injection), intramuscularly - 3-5 ml 10 % solution 1-2 times a day. Inside take 0.2-0.5 g 3-4 times a day.

Apply also in the form of rectal candles containing 0.5 g of diprophylline. They are introduced into the rectum 1 Candle 1-2 times a day (in the morning and in the evening) after a preliminary cleaning enema or spontaneous intestinal emptying.

The course of treatment is usually 10-20 days. If necessary, the course is repeated after a 3-5-day break.

Contraindications. The use of diprophylline, especially intravenously, contraindicated with a sharply reduced arterial pressure, paroxysmal tachycardia, extrasystolia (violation of heart rhythm), epilepsy. It should also be used the drug in heart failure, especially associated with myocardial infarction, when there are coronary failure (discrepancy between the need of the heart in oxygen and its delivery) and heart rate disorders.

Release form. Powder; Tablets 0.2 g; 10% solution in ampoules of 5 ml; Candles containing 0.5 g of preparation.

Storage conditions. List B. in the cool, protected from light place.

Angistin (Angiseedin)

Combined drug containing diprofillin, tritirtit peritrol, caffeine, approxide hydrochloride, valerian extract, phenobarbital.

Pharmachologic effect. It has spasmolitical (removable spasms) and sedative (soothing) action, expands coronary (cardiac) vessels, stimulates the contractions of myocardium (heart muscle), increasing the emission and minute volume of the heart.

Indications for use. Chronic coronary failure (discrepancy between the need of a heart in oxygen and its delivery), prevention of angina attacks, various kinds of cardialgia (pain in the left half of the chest).

Method of use and dose. Assign 1 tablet 3 times a day after meals.

Release form. Tablets containing diprophylline 100 mg, peritrol tritirtitis 12.5 mg, caffeine 50 mg, approxide hydrochloride 15 mg, Valerian extract 30 mg, phenobarbital 15 mg.

Storage conditions. List B. in light-protected place.

Katasma (Catasma)

Combined drug containing diprofillin, sodium salt of succinic acid, sodium guaiacolcololate, Cofamin Bristetini.

Pharmacological action is due to the properties of components included in it. Diprophiline has bronchorated actions, amber-sour sodium improves pulmonary ventilation, stimulating the respiratory center. Guaiacol derivatives are driving, anti-cataral (anti-inflammatory) action. Cofamine Bristetini (original caffeine derivative) has the properties of respiratory analeptics.

Indications for use. Asthmatic bronchitis, phenomena of bronchospasm (sharp narrowing of the lumen of bronchi)

with different pulmonary diseases bronchial asthma, pulmonary heart.

Method of use and dose. Assign from 1 to 3 ampoules per day intramuscularly or from 2 to 4 tablets per day.

Release form. 3 ml ampoules per pack of 10 pieces; Tablets for 20 pieces in the package. 1 ampoule contains 300 mg of diprophylline, 100 mg sodium salt Amber Acid, 100 mg of sodium guaicolocolate, 50 mg of cofamine bristetini. In 1 tablets contain 150 mg of diprophylline, 50 mg of amber-sour sodium, 100 mg of calcium guaicolocolate, 100 mg of cofamine bristers.

Storage conditions. List B. in a dry, light-protected place.

Naftidrofuril (Naftidrofuril)

Synonyms: Duzodril, cytoxide, Dubimax, Fuksaten, Iridax, Nafronil, Natifluks, naphtyfurine, Praxylene, etc.

Pharmachologic effect. Refers to 5-HT2 serotonin receptor blockers. The drug expands peripheral vessels (arteries), improves blood supply, oxygen support of tissues, as well as blood circulation in brain vessels, retina, and other organs.

Indications for use. Prescribed in case of circulatory disorders in peripheral vessels, especially lower limbs (intermittent chromotype, Reino disease, etc.), with trophic disorders of tissues (straggling, do not heal ulcers and "dr.), As well as with violations of the brain circulation, the blood supply to the eye dna and Dr.

Method of use and dose. Take Per OS (through the mouth) to 200-600 mg per day after meals. With acute vascular disorders, intramuscularly, intravenously or intraarterially 100 mg 2-3 times a day, and then go to a long reception of the drug PER OS.

Side effect. When taking PER OS loss of appetite, nausea, vomiting, diarrhea. With quick intravenous and intraarterial administration, some patients have symptoms of excitation, less often depression (depressed state).

Contraindications. Acute myocardial infarction, tendency to hypotension (decrease in blood pressure), acute hemorrhagic stroke (acute violation of cerebral circulation as a result of brain vessels), increased convulsive readiness, severe heart failure, severe heart rhythm disorders.

Release form. Dragee is 0.06 g per pack of 20, 50, 100 and 600 pieces. Dragee retard (long-acting) 0.1 g per pack of 20.50, 100 and 600 pieces. Capsules of 0.2 g per pack of 20 pieces. Ampoules containing 0.2 g of naphthidrofurila, in the package of 5, 10, 20 or 100 pieces.

Storage conditions. List B. in light-protected place.

But-SPA (NO-SPA)

Synonyms: DROTAVERIN hydrochloride, drootaverin, depthren, dihydroetserin, nuns, rospazin, tetraspasmine.

Pharmachologic effect. It has pronounced antispasmodic (removable spasms) action.

Indications for use. Spasm of the stomach and intestines, spastic constipation, attacks of bile and urolithiasis, angina, spasm (sharp narrowing of the lumen) peripheral vessels.

Method of use and dose. Inside 0.04-0.08 g 2-3 times a day; intramuscularly 2-4 ml of 2% solution; Intravenously (slow) 2-4 ml of 2% solution, if necessary, intraarterially (obliterating endarteritic / inflammation of the inner shell of the limbs with a decrease in their lumen /).

Side effect. Dizziness, heartbeat, sweating, feeling heat, allergic dermatitis (skin inflammation).

Contraindications. Hypertrophy (increasing volume) of prostate gland and glaucoma (increased intraocular pressure), especially the closed breeding form.

Release form. Tablets of 0.04 g per pack of 100 pieces; Ampules with a capacity of 2 ml, containing 0.04 g, in the package of 50 pieces.

Storage conditions. List B. in a dry, light-protected place.

Bishpan (Bispan)

Combined preparation containing but-shu and cholinolithic drug isopropamide.

Indications for use. Used in intestinal spasms, spastic colitis (colon inflammation characterized by sharp reductions), acute and chronic hyperacid gastritis (inflammation of the stomach due to persistent increase in acidity), ulcerative disease of the stomach and duodenum, cholecystopathy (gallbladder disease), spasters of ureters and other diseases accompanied by spasms of smooth muscles of internal organs.

Method of use and dose. Prescribe an adult in acute cases 1-2 tablets 2-3 times a day; In chronic cases - 1 tablet 2-3 times a day for 3-4 weeks.

Side effects and contraindications are the same as for no-shop

Storage conditions. List B. in a dry, light-protected place.

Nicospan (Nicospan)

Combined drug containing but-shlu and nicotinic acid.

Pharmachologic effect. It has a pronounced vasodilatory action.

Indications for use. Spasms (sharp narrowing of the lumen) of the brain vessels and peripheral vessels.

Method of use and dose. Inside after meals 1 tablet 1-3 times a day or 1-2 ml ("/ 2-1 ampoule) under the skin or intramuscularly 1 -2 times a day. If necessary, 1 ml of solution is slow to Vienna. With peripheral disorders Blood circulation (bombing) is introduced (slowly!) To the femoral artery of 1 -2 ml of solution.

Side effects and contraindications are the same as for but-ships.

Release form. Tablets of 0.1 g of composition: but-shts - 0.078 g, nicotinic acid - 0.0022 g; Ampoules in 2 ml of composition: but-ships - 0.0642 g (64.2 mg) and nicotinic acid - 0.0176 g (17.6 mg), in a package of 10 pieces.

Storage conditions. List B - in dry, protected from light place.

Papaverini Hidrochloride (Papaverini Hidrochloriduin)

Pharmachologic effect. Motropic antispasmodic (removing spasms of smooth muscles) drug. Lowering the tone and reduces the contractile activities of smooth muscles and has a vessel and antispasmodic vessel (removing spasms). In large doses, lowers the excitability of the heart muscle, slows down intracardiac conductivity.

Indications for use. Spasms (sharp narrowing of the lumen) of the brain vessels, angina, endarterite (inflammation of the inner shell of arteries), cholecystitis (inflammation of the gallbladder), pylorospasm (spasm muscles of the stomach), spastic colitis, spasm of urinary tract, bronchospasm (narrowing of the bronchi lumen).

Method of use and dose. Inside adults take 0.04-0.08 g (40-80 mg) 3-4 times a day; Children - not 3-4 times a day: aged 6 months. up to 2 years - at 0.005 g (5 mg) on \u200b\u200breception, 3-4 years - at 0.005-0.01 g, 5-6 years - 0.01 g, 7-9 years - at 0.01-0.015 , 10-14 years old - at 0.015-0.02 g at the reception. When vomiting or difficulty swallowing is prescribed in the form of supospositors (candles) rectally (in the rectum) of 0.02-0.04 g 2-3 times a day (adult). Under the skin and intramuscularly administered by adults 1-2 ml (more often 2 ml) 2% solution, and intravenously in the same dose (very slowly!), Dilving a 2% solution of hydrochloride papaverine in 10-20 ml of isotonic sodium chloride solution. Children are given in smaller doses, respectively, age. Higher doses for adults inside: one-time - 0.2 g, daily - 0.6 g; Under the skin, intramuscularly and in Vienna: one-time - 0.1 g, daily - 0.3 g. The highest doses for children inside between the ages of 6 months. up to 1 year: one-time - 0.005 g, daily - 0.01 g; at the age of 2 years - one-time 0.01 g, daily 0.02 g; 3-4 years old-ourselves 0.015 g, daily 0.03 g; 5-6 years old-ourselves 0.02 g, daily 0.04 g; 7-9 years - one-time 0.03 g, daily 0.06 g; 10-14 years - one-time 0.05-0.06 g, daily 0.1-0.2 g. Children up to 6 months. Do not prescribe.

Side effect. Atrioventricular blockade (violation of the excitation on the conductive heart system), ventricular extrasystole (violation of the heart rhythm), intravenous administration Reduced blood pressure, constipation.

Contraindications. Violations of atrioventricular conductivity (violation of excitation on the conductive heart system).

Release form. Powder; Tablets at 0.01 g for children in packing 10 pieces; Tablets at 0.04 g per pack of 10 pieces; Ampoules 2 ml of 2% solution per pack of 10 pieces; Rectal suppositories (candles for introducing into the rectum) 0.02 g per pack of 10 pieces.

Storage conditions. List B. in a well-appointed container in a secure place.

Nikoverin (Nicoverinum)

Combined preparation containing papaverine hydrochloride and acid nicotinic.

Indications for use. As antispasmodic (removable spasms) and a vasodilator with hypertension (permanent lifting of blood pressure), angina, migraine, endarterite (inflammation of the inner shell of arteries).

Method of use and dose. 1 tablet 2-3 times a day.

Side effect. Hyperemia (redness) of the skin, the feeling of heat.

Release form. Packing pills in 10 pieces containing papaverine hydrochloride 0.02 g, Nicotinic acid 0.05 g.

Storage conditions. List B. in a dry, light-protected place.

Papazohim

Combined preparation containing papaverine hydrochloride and dibazole.

Indications for use. With hypertension (resistant increase in blood pressure) and angina.

Method of use and dose. 1-2 tablets 2-3 times a day.

Side effect. Reducing cardiac output.

Contraindications. Hypertonic disease in old age.

Release form. Tablets containing papaverine hydrochloride and dibazole 0.03 g, per pack of 10 pieces.

Storage conditions. List B. in a dry, light-protected place.

SPASMOVERALGINUNI (SPASMOVERGINUNI)

Pharmachologic effect. Combined drug. It is a combination of antispasmodic drugs (spasms removable), analgesic (anesthetic) and sedative (soothing) properties. Ephedrine opposes the oppressive influence of phenobarbital.

Indications for use. Spasms (sharp reduction) of the muscles of the gastrointestinal tract; bile colic; kidney colic; bladder spasms; migraine; Algodismenorye (painful menstruation).

Method of use and dose. Doses are installed individually. Usually adults are prescribed 1 tablet 1 -3 times a day. Children aged from 6 to 15 years old are prescribed by "/ 2-3A tablets 1-3 times a day.

The development of addiction is possible (reduction or lack of effect with long-term reuse).

With prolonged intended purpose, spasmodulin should be regularly monitored by the picture of the blood.

Side effect. Possible leukopenia (reducing the level of leukocytes in the blood) up to the agranulocytosis (a sharp decrease in the number of granulocytes in the blood). Allergic reactions in the form of skin rash. Symptoms caused by anticholinergic effect (at the expense of atropine): dry mouth, accommodation violation ( spectatic perception), Tachycardia (rapid heartbeats), atony (loss of tone) intestines, difficult urination.

Contraindications. Increased sensitivity to the components of the drug; lactation; leukopenia; Porphyry ( hereditary violation exchange of porphyrins); constipation; mechanical stenosis (narrowing) of the gastrointestinal tract; Megolon (significant expansion of a part or the entire colon); arterial hypertension (lifting arterial pressure); severe heart failure; violations of cardiac rhythm, including tachycardia; coronary artery disease; acute myocardial infarction; thyrotoxicosis (thyroid disease); hypertrophy (increasing volume) of prostate gland; glaucoma (increased intraocular pressure); Treatment of Mao inhibitors. The drug is not prescribed to children under 6 years. During treatment, alcohol should not be used.

The drug can reduce the ability to concentrate attention, so caution should be taken when driving vehicle and maintenance of mechanisms.

Release form. Tablets containing proppopenazone 150 mg, phenobarbital 20 mg, pipaverine chloride 30 mg, codeine of dihydrophosphate 15 mg, ephedrine of chloride 5 mg, atropine metobromide 0.5 mg, in packing 10 pieces.

Storage conditions. List B. in a dry, light-protected place.

Papaverin hydrochloride is also included in the preparations of Astfillin, PAGULUFERAL, Mixed Mixture, Andipal Tablets, Besalol Tablets, PA-LUFIN Tablets, Tepaphillin Tablets, Teodibav-Rin Tablets, Tablets.

SPASMOLITITIM (SPASMOLYTIMIM)

Synonyms: Adiphenine, Difazil, Vagospazmil, Vegantin, Trazentin.

Pharmachologic effect. It has M-cholinolytic activity, suppresses n-cholinoreactive systems of the body and has spasmolytic (removable spasms) action.

Indications for use. ENDARTERIT (inflammation of the inner shell of arteries), pylorospasm (spasm muscles of the gastric gatekeeper), spastic colic, peptic ulcer of the stomach and duodenum.

Method of use and dose. Inside after a meal of 0.05-0.1 g 2-4 times a day, intramuscularly 5-10 ml of 1% solution.

Side effect. In case of overdose, dry mouth, dizziness, headache, feeling of intoxication, pain in the opposite region, local anesthesia.

Contraindications. Glaucoma (increased intraocular pressure), work requiring a quick mental and physical reaction.

Release form. Powder.

Storage conditions. List B. in a dry, light-protected place.

Phoenicaberan (Phenicaberanum)

Pharmachologic effect. Antispasmodic (removable spasms).

Indications for use. Used in chronic coronary insufficiency (inconsistencies between the need of the heart in oxygen and its delivery) with the attacks of angina; For diseases of the digestive tract, accompanied by smooth muscle spasms, chronic cholecystitis (gallbladder inflammation).

Method of use and dose. Inside (regardless of meals) are prescribed 0.02 g 3-6 times a day, intramuscularly - 2 ml of 0.25% solution (0.005 g) 2-3 times a day. The duration of the course of treatment is 4-6 weeks.

The drug is more effective in parenteral (intramuscular) administration than when taking inside.

To relieve (removal), the attack of the phenicaberan angularity is administered only intramuscularly (2 ml of 0.25% solution).

Side effect. Dizziness, headache, total weakness, worsening appetite; In these cases, reduce the dose or temporarily stop receiving the drug.

Contraindications. Chronic nephritis (kidney inflammation) with edema and violation of the agricultural function of the kidneys, bleeding ulcer of the stomach and duodenum, diabetes, pregnancy. Caution is needed with myocardial infarction (in the acute period). With an increase in blood pressure, the drug is canceled.

Release form. Shell-covered tablets, 0.02 g per pack of 20 pieces; 0.25% solution in 2 ml ampoules per pack of 10 pieces.

Storage conditions. List B. in light-protected place.

The human body is a reasonable and fairly balanced mechanism.

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Sprupping for intestines list of drugs

Safety Preparations - Classification, Action, Application Instructions and Reviews:

Antispasmodics belong to drugs, eliminating spastic pain, one of the most unpleasant symptoms in the presence of pathologies of internal organs. Probably reduce pain, relax muscles, remove spasm.

Help well, act quickly.

Classification

Classified antispasmodics preparations for the mechanism of their action to the following:

• Miotropic, rendering effect directly on the cells of smooth muscles, while changing inside the biochemical processes inside them. The basis of these spasmodics are: Gimekromon, Galidor, Bromide Panoverei, bromide oliconium, furniture, Nitroglycerin, Dinitrate Isosorbide, Gimekromon, Bendazole, Papaverin, Bencyclan, Drozerin. Pretty extensive list of antispasmodics drugs.
• At headache, neurotropic, affecting the transmission processes in the nerves of nerve impulses, which stimulate the smooth muscles of internal organs. This is mainly M-cholinoblocators, such as Atropine sulfate and similar to it: Buskopan, Bustlebromide of Hosqing, Ganglefen, Aproofen, Difazil, Arpenal, Bromide, Metocynes, Handicraft preparations, Hyoscylamin, Skopolamine, Platimyllin.

Including the classification of antispasmodics preparations by their origin:

• Artificial drugs.
• Natural spasmolitics: mint, Chernobyl grass, Pijma ordinary, Benne Black, May Lily of the Lily, kidney tea (orthosifer), AIR marsh, soul man, chamomile, beautification, pharmacy lomacity.

Form release

We produce antispasmodics in shape:

• Ampoules (intramuscularly and intravenously) - "Platifillain", "Papaverin", "Spacovin", "But-Shpa", "Drugsin", "Trigan", "Dibazol".
• Capsules - "Duspatalin", "Sparex".
• Drops taken inside - "Zelenin", "Voserdin".
• Whole fruits - cumin.
• Granule to prepare a solution - "plantacid", "PlanTaglucid".
• Rectal candle - "Papaverin", beautification extract, "buckopane".
• Tincture - tincture of peppermint.
• Tablets - "Platifillain", "Papaverin", "Besalol", "Bekarbon", "Papazole", "Trimedat", "Nicoshpan", "Vesicar", "Dicetell", "Spasierin", "Dryptan", "but-shpalgin "," Spasmodet-forte "," spasmol "," spasmodet "," but-shpa forte "," nos-sconce "," drootaverin-elda "," drootaverin "," but-shpa "," Galidor "," Buckopan.

Indications for use

General indications for the use of drugs are: cardiovascular diseases, hypertonus, elimination of pain in irritable intestinal syndrome, removal of colic, elimination of urinary and biliary spasms, smooth muscles of the gastrointestinal organs.

All types of spasmolytic drugs need to be used, strictly observing the directions of the doctor, provided that the diagnosis is supplied accurately.

Antispasmodics Children

Each manufacturer shall indicate the features for taking the drug by children. For example, some forms of doll are not prescribed to children under 2 years old, others recommend to use for children for 1-6 years by a daily dose equal to 40-120 mg, up to 3 times a day, children from 6 years dose at 80-200 mg to 5 times in day.

Boutilbromide Giosqing is prohibited to give children under 6 years. Bromide Panovereiya is not recommended for children under 18. Natural antispasmodics are preparing from plants of individual or fees that contain stalks, leaves, roots, flowers. They are prescribed for children with diseases that are accompanied by convulsions and spasms. Antispasmodics for intestines can be prescribed.

For newborns, they apply very limited. There is only a small number of items allowed by pediatricians to receive babies. More often, doctors prescribe vegetable drugs, which contain natural anti-spasmodics: dill oil, anise, fenhel fruit, peppermint.

With headache

Antispasmodics with headaches, which arose due to blood circulation disorders in the brain or spasms of the brain vessels, help reduce its intensity (beziclan tablets, "Papaverin", "Drozerin"). Including facilitating attacks and give a good effect. Preparations are complex, containing painkillers and anti-inflammatory components, in addition to spasmolitics. The list of preparations in abdominal pain is presented below.

With cystitis

When cystitis, the appointment of antispasmodics can contribute to the removal of the painful spasm, a decrease in the tone, reducing the urges to urination and relieved unpleasant symptoms. For therapy of this disease, DROTAVERIN-based drugs are effective: "Belliklan", the injections of "platificillin", Papaverin tablets and "but-shts".

Elderly people spasmolytics are prescribed with caution, paying attention to the accompanying pathologies and diseases, including at the same time receiving other drugs, the impact of which can affect the effectiveness of admission of antispasmodics and opposite.

Spasmolytics renal colicwhich are characterized by pronounced pain, primarily used to remove pain during an attack. The patient is prescribed injecting "platificillin" in 1 mg or tablets of 5 mg, children by age dosage is prescribed from 0.2 to 3 mg, and the Tablets "Atropine" and "DroTaveberin" can also be appointed.

Intestinal preparations

When appointing intestinal drugs, spasmolitics should be borne in mind that they can cause constipation, especially in the elderly with a weakened intestine function. Therefore, such a moment must also be taken into account when prescribing drugs. Excellent spasmodic effect with various intestinal diseases has a bromide of Panovereiya (taken during meals with a large amount of liquid, not chewing and not resolving 50 mg to 4 times a day). His reception is not recommended for children.

For the treatment of stool disorders, abdominal pain, in the syndrome of irritated intestines and secondary spasms, use the preparation "furniture" 1 tablet 3 times a day, 1 capsule 2 times before meals in 20 minutes (daily dosage is 400 mg). In the intestinal diseases, the use of cholinolithic agents is limited due to low efficiency and side effects. The list of spasmodics for intestines can be clarified by the doctor.

Slavsmolitics at cholecystitis contribute to the decrease in pain symptoms, for example, prescribe cholinolics ("Platifillain", "Atropine"), as well as DROTAVerin and Papaverin. The most productive may be considered the appointment of the furniture of the furniture 2 times a day of 200 mg, the bromide of Pannoverey 3 times a day at 100 mg. The use of tonic drugs is shown in hypotonic dyskinesia, but it is worth avoiding antispasmodics. For holding therapy with cholecystitis, it is recommended to take an infusion from the peppermint (natural spasmolytic) at half a glass after the meal 3 times a day.

With osteochondrosis

In osteochondrosis, antispasmodics contribute to the assistance to remove the muscle tension, improving the blood circulation of the local zone, and this, in turn, reduces the severity of pain and affects the patient's well-being. With osteochondrosis, it is prescribed "DROTAVERIN" and "PAPAVERIN".

In the gastritis of antispasmodics are called one of the most effective drugs that facilitate painful and unpleasant sensations. Reviews of this testify. It is necessary to take into account when receiving that cholinoblocators can contribute to the appearance of an additional effect, namely a decrease in the acid indicator, so when they are taken, redundant secretion take into account.

Urolithiasis disease

With urolithiasis, one of its manifestations characterize changes in the kidneys and urinary trait. During colic, pain arises, rarely sharp, more often constant, stupid, buty, and therefore the reception of antispasmodic drugs, complex including, helps facilitate the condition of the patient by removing the spasm of the smooth muscles of ureters. Bencyclan and DroTaverin, including spasmolyts complex, must be combined with drugs that are able to lead to disbelief and destroying stones.

Colitis

If the patient has an ischemic or chronic colitis, it is prescribed "DROTAVERIN" and "PAPAVERIN" of 1-2 tablets 2 - 3 times a day, as well as "Platifillin" to weaken the turbulent intestinal peristalsis, remove spasms and reduce pain. During diarrhea, it should be combined with an atropine sulfate enveloping and binders.

Antispasmodic plants are accepted as informants or bravery and instructions. In addition, they are often part of the main operating components of various drugs. The drug can fully enjoy natural origin or combine synthetic and natural ingredients.

Special group

The special group of spasmolitics includes drugs complex (for example, analgesics and spasmodics "Spasmalgon", "Baratgin"), which combine antispasmodics of various spectrum of action, as well as sodium hydrocorbonate, sodium metamizole, nicotinic acid, vegetable extracts (pyrhem, beautification, mint) , painkillers and other components. These antszmolytics preparations with headaches help very well.

Reviews show that they are effective in brain spasms, peripheral arteries, help eliminate functional disorders Cardiovascular system, as well as spastic pain. Before applying one or another drug, it is necessary to seek advice from the doctor.

We reviewed a list of spasmolytic drugs during pain. We hope the information was helpful to you.

www.syl.ru.

Safety spasmolitis - list of medicines

Antispasmodics - drugs to eliminate painful sensations, provoked by smooth muscle spasms. These pharmacological preparations Not only reduce the severity of symptoms, but also used in the complex therapy of various diseases. Most often, antispasmodics are used in the treatment of pathologies of the organs of the urinary and cardiovascular system, as well as the gastrointestinal tract. Manufacturers produce preparations in the form of injection solutions, tablets, capsules, dragee, rectal suppositories. In the recipes of traditional medicine, herbs, flowers and roots possessing antispasmodic properties are mentioned.

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Affecting the smooth muscle muscles of internal organs, spasmolytics eliminate the cause of pain

Musculatory man consists of smooth and transverse muscles. Reducing the latter controls the central nervous system. With the help of transverse muscles, a person retains equilibrium, moves, changes the position of the body in space. Basically, they are located in the limbs, a torso neck and head. Smooth muscle muscles is in the walls:

• lymphatic vessels;
• arteries;
• capillaries.

Hollow internal organs are reduced due to the presence of smooth muscle shells. They support the tone of all blood vessels, thanks to them, food is moving along the gastrointestinal tract. If a person could control smooth muscles, then there would be no problems in various systems of its livelihoods. But this type of musculature is under the control of the vegetative system, so innervation disorders and other disorders lead to spasms.

Restore the functional activity of the stomach, intestines, a bile or bladder help drugs. These include antispasmodics, relaxing the smooth muscles of hollow internal organs. As a result of the reduction of the tone of muscle fibers, the uncomfortable sensations provoked by spasms quickly stop.

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Classification

Spast pain is an integral part of the clinical picture of many diseases. Their treatment begins with the reception of antispasmodics, which facilitate symptoms, allow you to carry out full-fledged etiotropic and pathogenetic therapy. Some of these drugs (for example, Duspatolyalin) affect only the smooth muscular muscles of certain internal organs. Such selectivity helps to avoid complications and unwanted consequences. Other antispasmodics (DROTAVERIN) have an impact on all smooth muscles in the human body. This significantly limits the circle of patients in the treatment of which such drugs can be used.

Warning: "Wide-spectrum spasmodics with caution are used in the therapy of pregnant women. Preparations have an impact on the uterus, which can cause premature births. Women carrying a child should seriously refer to the choice of tablets even from banal headaches. "

Antispasmodics are produced in various dosage forms, including in rectal suppositories

Motropic drugs

Under the action of myotropic spasmolitics, ion balance in cell membranes as a result of direct impact on smooth muscular muscles. Cell contractual activity decreases after the launch of complex biochemical reactions. Antispasmodics of this group are able to relax smooth muscles of certain internal organs, reducing the severity of pain and uncomfortable sensations. These drugs include:

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• Papaverine;
• Beziclan;
• Halian;
• DROTAVERIN;
• Gimekromon;
• Nitroglycerine;
• Isosorbide dinitrate;
• Bendazole;
• Gimekromon;
• Furniture.

Motropic antispasmodics are used in disruption of the gastrointestinal tract, menstrual pains, disorders of the digestiveness of neurogenic etiology. They quickly reduce the tone of the smooth muscular muscles of the organs. Papaverin hydrochloride normalizes the internal conductivity of the heart muscle.

Warning: "SPASMOLITITICS different species Cannot be taken without appointing a doctor. Preparations possess various contraindications, among which intestinal infections, Crohn's disease, children's age. "

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Neurotropic drugs

Neurotropic antispasmodics are drugs that can influence pulses in the vegetative nervous system. Such drugs are not direct, but an indirect impact on the smooth muscular muscles of internal organs. They are used in the treatment of diseases of the respiratory and biliary tract, organs of the urinary system and the digestive tract. In addition to therapeutic, neurotropic drugs also show antispasmodic properties. The following drugs have the greatest therapeutic efficacy:

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• Difazil;
• Buckopan;
• Skopolamine Arpelin;
• Hyoscyamine;
• Platifillin;
• Aproofen;
• Atropine sulfate;
• Ganglefen.

Neurotropic antispasmodics may differ in the mechanism of impact on smooth muscular muscles. Some preparations normalize the innervation of pulses to the central nervous system due to its ability to influence the receptors located in the blood vessels. Due to such a mechanism, the activity of endocrine glands is reduced, heart rate is studied, the secretion of gastric juice increases.

Second group neurotropic spasmolitics It acts more selectively. They influence directly on the bladder receptors, the urethra, the stomach, intestines. Active substances These drugs do not penetrate the smooth muscle fibers of the internal organs of other livelihood systems.

But-shpa - one of the most commonly used spasmolitics to relieve pain

Neuromiotropic drugs

This type of spasmolitikov exhibits myotropic and neurotropic properties. Drugs are attributed to this group not only chemical compositionBut also on the integrated impact on the smooth muscular muscles of internal organs and blood vessels. Camilochine has neuromiotropic effect due to its structure, and other drugs contain several ingredients with certain antispasmodic properties.

Combined drugs

For combined, or complex, spasmolitics are characterized by a manifestation of several therapeutic effects. Baratgin, Spasgan, Spasmalgon have an anesthetic and antispasmodic effect. Some drugs helps to stop the inflammatory process and even reduce the increased body temperature. As a result, the condition of a person is improved by eliminating the cause of pathology and the symptoms provoked by it.

Therapeutic properties

There is another classification of antispasmodics, which was drawn up by the general therapeutic effects of drugs on the human body. Also, pills and injection solutions show side effects that do not allow them to be used in patient therapy with chronic diseases. For example, some antispasmodics are able to reduce blood pressure. They should not be taken to normalize the operation of the gastrointestinal tract with hypotonix.

Anesthetics

These medicines doctors recommend patients who have been diagnosed cholecystitis, pancreatitis, bile colic. They are effective in painful spasms during menstruation. Due to the ability to expand blood vessels, painkillers are applied with such pathologies:

• migraines;
• arterial hypertension;
• blood violations of the brain.

Some antispasmodics eliminate heart pains, others affect the smooth muscles located in bronchi. This group includes medicinal products (Duspatalin), which are used in the treatment of diseases of the digestive organs. They not only reduce the severity of pain after meals, but also help to normalize the operation of the gastrointestinal tract.

Vasteransior

The group of myotropic spasmolitics includes drugs with vasodilative actionwhich arises due to the relaxation of the smooth muscles of hollow internal organs and blood vessels. Preparations are used primarily to eliminate pain syndrome. Motropic antispasmodics are used not only for the treatment of organs of various systems of vital activity, but also as a preventive means to prevent recurrence of chronic pathologies.

Eufillin manifests not only the properties of antispasmodics, but also is able to expand blood vessels. This drug is often used in an injection dosage form to reduce persistent venous or intracranial pressure. Eufillin is not used to treat patients with coronary insufficiency, as one of its side effects is tachycardia.

Hypotensive

Nicotinic acid, phenobarbital and papaverine hydrochloride are used comprehensively to relieve spasms of blood vessels located in the brain and reduce blood pressure. The use of spasmolitics in hypertensive therapy is most relevant in atherosclerosis. DROTAVERIN although slightly, but reduces blood pressure. This drug does not affect the cause of pathology, but it eliminates its main symptom - headache.

Recommendation: "If the pain in the organs of the digestion, head, at the bottom of the abdomen arise more often than 2-3 times a month, then you should not drown them with antispasmodics. It is necessary to sign up for a consultation to the doctor for examination and establish the cause of uncomfortable sensations. "

All materials on Ozhivote.ru are presented to familiarize themselves, contraindications are possible, a consultation with the doctor is obligatory! Do not do self-diagnosis and self-medication!

ozhivote.ru.

Slavsmolitics: a list of drugs and varieties

Antispasmodics - drugs related to a group of pharmaceutical agents intended for efficient and operational removal of pain syndrome with a strong negative effect for the body. The group under consideration of the medical staff actively copes with strong pains having a variety of "nature" of origin, starting from the injury, ending with menstrual pains.

Mechanism of action

Using antispasmodics, you can remove almost any pain associated with gastrointestinal problems, mechanical injury (blows, malaise during rehabilitation after fractures), menstruation.

Perhaps the most common symptom of diseases of the gastrointestinal tract is abdominal pain.

Preparations related to the spasmodics group help it help. However, it is not necessary too involved in these drugs (and to appoint them yourself without prior consultation with the doctor - especially).

With an erroneous selected dosage, they can cause serious side effects.

We emphasize: all information that is prepared by the author is presented below, wears only educational character.

Frequently used antispasmodics: types and names

I will not go deep into chemistry. We restrict ourselves to the general provisions that are of interest to the patient.

Miotropic Preparations - sodium and calcium channel blockers, nitroce oxide donators, phosphodiesterase inhibitors - influence directly on the myocytes of smooth muscles.

These spasmolitics include:

• dROTAVERIN (as a separately existing drug and active ingredient);
• papaverine;
• halian;
• savroom;
• gimekromon;
• dicetell;
• duspatalin;
• buckopan et al.

The essential lack of "old" drugs - papaverine, drootaverine - their systemic effect on all organs having smooth muscles, incl. - on the vascular wall. For the course reception, doctors are trying to prescribe patients with relatively recently developed spasmolitics with a selective effect - for example, Duspatalin (mebelverine hydrochloride), a bustle (Bushoszin of Boutilbromide), a spasmodomomen (oliconium bromide).

The sale of most listed drugs is carried out without a recipe.

Funds of another subtype - neurotropic - Work indirectly. Among them are alkaloids, central and peripheral M-cholinoblocators.

They purposefully affect cholino - or adrenoreceptors, adjusting the pulse in the vegetative nervous system. Among them:

• aproofen;
• ganglefen;
• atropine;
• difazil;
• bustle.

N.N.Dekhnichn indicates (1):

Due to nonspecificity and systemics of the cholinoblocking effect of neurotropic spasmolitics, most drugs of this group cause an atropine-like unwanted drug reactions, and therefore are currently being used in gastroenterology.

As A.A. Zvyvygin, A.V.Pocivalov, E.D. Cherkeeper (2), "Arsenal of Antispasmodic Funds constantly apieces." It is not surprising - preparations that have pain, always enjoy in demand.

Indications for use

The main indication, of course, spasms with functional disorders and chronic diseases gastrointestinal tract. Preparations of the group are prescribed during gastritis, ulcer of the stomach and DPK, dyskinesia of biliary tract, biliary disease, irritable intestinal syndrome, renal and intestinal colic, pancreatitis.

E.A. Beluesova writes (3):

In case of chronic FR gastrointestinal tract, all antispasmodics are applied by courses for 2-3 weeks. It is such a duration of reception not only to bind pain, but also provides the restoration of the normal transit of intestinal content. With sharp episodes of functional pain, drugs can be applied once or shorter courses.

To complete the normalization of the motor function and eliminate pain in the long-term perspective by antispasmodics monotherapy, as a rule, it is not enough, but they turn out to be a very effective component of comprehensive treatment.

Basic contraindications

The use of the group's funds is usually contraindicated if the patient suspect the following pathologies:

1. separate types of colitis;
2. toxic megacolon;
3. microbial diseases of the intestine;
4. crohn's disease;
5. tuberculosis.

Pregnant women are not recommended antispasmodics of both species. Do not use them and people who spend many hours before dangerous moving mechanisms or by the wheel - some violation of coordination, braking psychomotor reactions, is not excluded.

Possible side effects

For each drug, they are their own (read the instructions carefully!). The most common unwanted reactions to antispasmodics:

• dry mouth;
• violations;
• heart palpitations;
• nausea;
• constipation;
• headache;
• redness of the skin;
• worsen sleep.

If you find these and other changes in well-being against the background of the course of treatment, you must urgently inform the doctor about the current situation.

Literature:

1. N.N.Dekhnich, "The use of modern spasmolitics in gastroenterology", "Vestnik Smolensk State medical Academy", №2, 2012
2. A.A. Zvyvygin, A.V.Pillavalov, E.D. Itary, "Safety of the treatment of gastroenterological diseases in children: comparative characteristics and application possibilities", "Pediatrics", T.91, №4, 2012
3. E.A. Belowov, "Safety Solvolytics in Gastroenterology: Comparative Characteristics and Indications for Use", "Pharmatek", №9, 2002
4. "Gastroenterology. National Guide "Ed. V.T. Ivashkin, T.L. Lapina, Moscow, "Gootar Media", 2008

Spasmolytiki - This is a group of medicines that differing in terms of action, remove spasm and painful syndrome in various organs (bronchi, gastrointestinal tract, vessels, etc.).

Spasm is a pathological reinforced reduction in smooth muscle cells in organs arising under the influence of adverse factors and manifested by pain syndrome. Most diseases from the gastrointestinal tract appear pain on the background of spasm. To relieve these symptoms, gastrointestinal antispasmodics are used, which are included in the common group of spasmolitics, but differ in a more selective action on the digestive tract.

Antispasmodics, depending on the mechanism of action, are divided into two large groups:

Motropic spasmolitis

The mechanism of action is based on removal of spasm by direct impact on smooth muscle cells. Preparations of this group can be used for a long time.

The following myotropic spasmolytics, which are used in gastroenterology are distinguished:

Neurotropic antispasmodics

The mechanism of action of drugs from this group is associated with blocking the excitation of the nerve end or ganglia to smooth muscle cells of the internal organs.

Most drugs relate to. The antispasmodic effect is associated with blocking M-cholinoreceptors in the human body. These receptors are responsible for the secretion of hydrochloric acid in the stomach, the operation of salivary and sweat glands, increase the tone of smooth muscles in the digestive tract, reduce the heart rate. When they block them, there is a relaxation of the muscles of the gastrointestinal tract, especially the upper departments (esophagus, a sphincter Approve, stomach, gallbladder). M-cholinoreceptors are practically not found in the intestines, therefore, most drugs of this group have no effect on abdominal pain caused by the disease of the lower departments of the digestive tract, which limits their use.

Preparations:

Safety spasmodics for children

In childhood, the functional disorders of the gastrointestinal tract in the type of spastic dyskinesia are more common. All departments of the digestive system (gallbladder, intestines, stomach, etc.) are exposed to spastic state. Children for the treatment of such states are used both groups of spasmolitics, but the age limitations and features of the children's body are taken into account in different age ranges (the immaturity of some liver enzymes up to 12 years, the acidity of the stomach at an early age and in older children, etc.), drugs are prescribed strictly According to the testimony.

The following antispasmodic drugs are allowed to use children:

• DROTAVERIN.
• Papaverine.
• Bustle.
• Duspatalin.
• Dietetel.

Indications for application

• when;
• tenesms;
• ulceal duodenal and stomach disease;
• spastic dyskinesia of biliary tract;
• spastic colitis;

Contraindications

Natural antispasmodics

• Plantex.
• Ukrope fragrance.
• Gastroin.
• Platacid.
• Fennel fruit.

Other harness methods from pain

Non-male methods for removing pain spasms include physiotherapeutic procedures.