Where contains vitamin B6. Vitamin B6 (pyridoxine) vitamin B6 prick

11.08.2020 Information

Instructions for use:

Magne B6 is a drug designed to replenish magnesium deficiency in the body, as well as to eliminate disorders resulting from a lack of this trace element.

pharmachologic effect

Magne B6 is combined drugwhich includes magnesium and pyridoxine.

Magnesium takes part in many exchange processes, in particular, in reactions associated with muscle reduction and transmission nerve impulses. Since this inorganic element enters the body with food, a diet can lead to its deficit, malnutrition, poor intestinal absorption, excessive excavation by the kidneys. Also, the body may experience an increased need for magnesium during stress, increased mental and physical Loads, during the use of diuretics, during pregnancy.

In addition to magnesium, Magne B6 also contains vitamin B 6 (pyridoxin), which also participates in many metabolic reactions, including in the exchange processes occurring in the nervous system. Vitamin B 6 improves magnesium absorption in the digestive tract, and also contributes to its penetration and deduction in cells.

From the adopted dose of Magne B6 in the digestive tract is absorbed half.

Indications for the use of Magne B6

sleep disorders;
increased fatigue, mental and physical overwork, asthenia;
irritability, increased nervous excitability;
feeling of tingling;
gastrointestinal spasms, pains and muscle spasms;
manifestations of anxiety attacks that are accompanied by intensive breathing;
rapid heartbeat.

Magne B6 during pregnancy, as a rule, is prescribed with an increased tone of the uterus, the threat of miscarriages, cramps.

Contraindications

Magne B6 is not prescribed at:

severe renal failure;
intolerance to fructose, deficiency of sucrose-isomaltose, disturbed suction of galactose or glucose;
phenylketonuria (violation of the metabolism of amino acids, in particular phenylalanine);
hypersensitivity to Magna B6 components.

The drug is contraindicated to children under 1 year and women during breastfeeding period.

Apply with caution of Magne B6 instruction recommends with moderate renal failure.

Instructions for use of Magne B6

In one tablet of the drug contains 470 mg of magnesium of dihydrate lactate and 5 mg of pyridoxine hydrochloride. One Tablet Magne B6 Forte includes 618.43 mg of magnesium citrate and 10 mg of pyridoxine hydrochloride. The drug is also available in the form of a solution for intake, one ampoule which contains 186 mg of sodium dihydrate lactate, 936 mg of magnesium of pidolata and 10 mg of pyridoxine hydrochloride.

Adults and children over 12 years old with a pronounced magnesium deficiency per day are prescribed 3-4 ampoules or 6-8 tablets, and during spasmophilia - 2-3 ampoules or 4-6 tablets. Children 6-12 years old Magne B6 It is recommended to take 1-3 ampoules or 2-6 tablets per day, for children 1-6 years old prescribe a solution in the form of a solution - 10-30 mg of magnesium per kilogram of weight per day. Take the drug should be taken until the restoration normal level Magnesium in the body.

As evidenced by reviews, Magne B6 usually shows and fixes therapeutic effect For one month.

Magne B6 during pregnancy, if the attending physician did not prescribe another scheme, apply 3 times a day for 2 tablets.

Magne B6 Forte Adults are prescribed at a dose of 3-4 tablets per day, and for children over 6 years old - 2-4 tablets per day, multiplicity of techniques - 2-3 times a day.

Side effects

Magne B6, the reviews confirm, transferred well, only in rare cases in patients were recorded in abdominal pain, meteorism, vomiting, nausea, diarrhea, constipation, allergic reactions.

Long-term use of magnet B6 in large doses can provoke peripheral neuropathy (damage to the peripheral nervous system) and paresthesia (disorder of sensitivity in the form of tingling, feeling of numbness and crawling of goosebumps).

Additional Information

Storage Magne B6 with room temperature In a dry and dark place will provide the shelf life of the drug for two years.

Vitamin B6 (pyridoxine) is a physiological role, signs of deficit, content in food. Instructions for use of vitamin B6

Thank you

The site provides reference information solely to familiarize yourself. Diagnosis and treatment of diseases must be under the supervision of a specialist. All drugs have contraindications. Consultation of a specialist is obligatory!

Vitamin In 6, this is a group name of three molding forms of the same bioorganic compound. Various forms One compound is called spatial conformations and carry various names that are used for quick and easy distinctions in writing and oral speech. However, the generally accepted name of Vitamin B 6 is pyridoxine.

Vitamin Name of 6

Vitamin B 6 is a substance having three different spatial forms of the molecule organization. All three form data have the same vitamin activity and are called vitamers in 6. The term "whitaer" is similar to the concept of "isomer" in organic chemistry. An isomer is a variant of the spatial orientation of the molecule of the same substance (see Figure 1).

Figure 1 - examples of hexane isomers.

Vitamin B 6 consists of three vitamers-isomers, each of which has the same vitamin activity. Vitamers are called differently - pyridoxol (pyridoxine), pyridoxal and pyridoxamine. All these names can be used to designate any form of vitamin B 6. However, in order to avoid confusion, Vitamin B 6 on the recommendation of the International Commission on the Nomenclature of Biological Chemistry is called pyridoxine, implying all three structural forms under this name, possessing the same activity - pyridoxine (pyridoxol), pyridoxal and pyridoxamine.

In addition, Vitamin B 6 is sometimes called old names - aermin or factor Y.which have been given a substance for several decades ago when they open and study properties. Today, these names in relation to Vitamin C 6 are rarely applied, but in some scientific and popular publications, they can still meet them.

In the human body, all three vitamin vitamers in 6 - pyridoxol, pyridoxal and pyridoxamine are converted into two active forms - pyridoxal phosphate and pyridoxamine phosphate. It is in the form of pyridoxalphosphate and pyridoxaminophosphate Vitamin B 6 providing physiological and biological effects in the human body. These names are also sometimes used in the literature to refer to the fact that it is about the active form of vitamin B 6.

Physiological role of vitamin B 6

Vitamin B 6 has the following physiological effects in the human body:
1. Regulation of protein metabolism;
2. Regulation of the exchanging of iron, its delivery to the bone marrow and other organs and tissues;
3. Regulates the excitability of the central nervous system.

The three listed physiological effect of vitamin B 6 has at the level of each cell. The effect is then summarized and the overall action at the level of the entire body occurs. Consider in detail, what is the essence of every physiological effect of vitamin B 6, and what role they play in maintaining and regulating life processes.

So, at the level of protein metabolism, pyridoxin is necessary for the mutual transformation and metabolism of amino acids that occur during transministration reactions, reaminting, deamination and decarboxylation. It is precisely the flow of reaction data and supports vitamin B 6 at the required level. The mutual transformation of amino acids occurs in the body constantly when it is necessary from one compound, which is currently quite a lot, to get another - existing in insufficient quantity. Thanks to this mechanism, one amino acid can turn into another - the one that is needed now for various protein synthesis processes. The process of transformation of amino acids to each other allows you to maintain a dynamic balance and not to allow the occurrence of a deficit due to the conversion of another substance existing in excess. In addition, Vitamin B 6 improves the absorption of amino acids from the intestine in the bloodstream and their subsequent transportation to various organs and tissues.

In addition, vitamin B 6 supports, activates and accelerates the transformation of dopamine in norepinephrine and glutamic and aspartic acid in amber acid, which significantly increase the rate of energy processes in cells. This means that under the influence of vitamin in 6 metabolism accelerates, the metabolism is faster, and, consequently, all cells are updated for a shorter period of time, supporting the youth and activity of the whole organism.

In the course of deamination reactions, acetylcoenzyme A, which is a key substance for the flow cykla Krebs. And the Krebs cycle is necessary for the synthesis of a universal energy molecule ATP (adenosine trifosphoric acid) From carbohydrates. The importance of the ATP molecule cannot be overestimated - because each cell uses energy in this form, and not in the form of proteins and carbohydrates received from food. Thus, to obtain a universal energy substrate, a cell is necessary to recycle carbohydrates, proteins and fats in ATP molecules. And Vitamin B 6 ensures the flow of the cascade of reactions (Crex cycle), during which carbohydrates are processed into ATP.

During the decarboxylation reactions, the formation of gamma-amine oil acid (gamc) from glutamic acid and serotonin from tryptophan is occurred. A gamma-aminobalic acid and serotonin, in turn, are the main brake mediators in the central nervous system. That is, under the influence of GABA and serotonin, braking and harvesting of excitation in the central nervous system. And since the decarboxylation reaction, during which the formation of a gamu and serotonin occurs, is regulated and started with vitamin B 6, so pyridoxin regulates the excitability of the central nervous system, not allowing it to be overcome. That is why, with a deficiency of vitamin B 6, there are signs of excessive excitation of CNS, such as a tendency to cramps, exaltation, etc.

Finally, Vitamin B 6 increases the amount of synthesized protein of siderophiline, which carries out the transfer of iron from the intestine in the fabric, including bone marrow. Thus, pyridoxine provides a bone marrow sufficient to heal the amount of iron. And therefore, with a deficiency of vitamin B 6, anemia may develop, because to deliver iron to the bone marrow, where hemoglobin is formed from it, due to the lack of sederophiline protein is simply impossible.

Vitamin B 6 for children - features of biological function

In the body of children, Vitamin B 6 performs the same functions as in adults. That is, pyridoxin accelerates metabolism, ensures the formation of carbohydrate energy, removes the excitation in the central nervous system, starts the transformation of amino acids into each other and is involved in the transportation of iron, creating conditions for hemoglobin synthesis.

In children, the ability of vitamin C 6 has a great importance to ensure the transformation of amino acids into each other, as they are necessary for the synthesis of protein and muscle construction, bones, connective tissue, vessels, nerves, etc. Summarizing, it can be said that the active protein synthesis is needed to a child for normal growth and harmonious physical development. And at each specific point in time, there may be a deficit of one or another amino acid, without which protein cannot be built. And then Vitamin B 6 comes in the literal sense of the word "on the revenue", which launches the process of turning one available in excess amino acid to another one that is not enough now. That is, pyridoxine in children provides normal physical development and full growth.

The function of maintaining the protein synthesis is important not only for growth, but also for normal immunity. After all, antibodies or immunoglobulins are protein structures that are constantly synthesized in the body to destroy various pathogenic bacteria, viruses, fungi, etc. And against the background of vitamin deficiency in 6, immunoglobulin synthesis can occur with insufficient intensity, which will manifest itself with a decrease in immunity in a child.

Also, Vitamin B 6 participates in insulin synthesis - very important to utilization of protein glucose, with an insufficient number of which a person develops a heavy, chronic metabolic disease - diabetes mellitus.

In addition, vitamin B 6 is necessary for the synthesis of sufficient amount of hemoglobin, since it stimulates the formation of a protein that delivers iron into the bone marrow, where hemoglobin assembly occurs. For children, this is especially important because they are intensively growing, and their blood volume is constantly increasing. If the amount of blood increases without proportional to increase the amount of hemoglobin, then the child will develop anemia.

Also, for children, the ability of vitamin B 6 to suppress the excitation and activate braking in the central nervous system. Given the prevalence of excitement over braking in the brain in children, it becomes clear that Vitamin B 6 is very important to maintain balance and prevent convulsive activity, irritability and excitability.

Pyridoxine also has very great importance For skin health, since vitamin prevents dermatitis of any origin, including allergic, seborrheal, fungal, psoriatic and diance. Considering that children often occur inflammatory and sprinkling rash on the skin, the role of vitamin B 6 as a substance that prevents these phenomena is very important.

Suction and removal of vitamin B 6

All three vitamehers in 6 are well absorbed from fine intestine In the blood, with a current of which is entered into the liver, where they are transformed into active forms - pyridoxal phosphate and pyridoxaminephosphate. It is in two active forms of vitamin B 6 that provides all its biological and physiological effects on the human body. After using pyridoxaminophosphate and pyridoxal phosphate turn into pyridoxic acid, which with urine with urine is derived from the body.

Vitamin C 6 - Symptoms

The deficiency of vitamin B 6 is rare, since pyridoxine is contained in sufficient quantities in many products consumed daily. Most often, the lack of vitamin B 6 is developing on the background various diseases The digestive tract in which its absorption into blood is disturbed (for example, malabsorption), as well as with pathologies associated with an accelerated distribution of protein, such as alcoholism, hyperthyroidism, fever of any gene or stress. In addition, pyridoxine deficiency can be formed in hereditary diseases, such as homocideinuria, cystoniauria, xanterenuria, pyridoxin-dependent convulsive syndrome and anemia.

Separately, it is worth mentioning as the causes of the development of vitamin deficiency in 6 medicinal preparations, preventing the suction of pyridoxine into the blood from the intestine. These preparations include anti-tuberculosis (isoniazide, fivazide, tubazide, cycloserine) and some other antibiotics (penicillamine, chloramphenicol), as well as ethionamide, levodopopopopia, estrogens and immunosuppressors.

Symptoms of vitamin C 6 deficit in adults

The deficiency of vitamin B 6 in adults is manifested by the following symptoms:

The deterioration of appetite up to its full loss;
Irritability;
Inhibition;
Depression;
Severe anxiety;
Convulsions and high convulsive activity;
Seborrheic dermatitis;
Hair loss;
Formation of kidney stones;
The emergence of abnormal waves on the electroencephalogram (EEG);
Neuritis and polyneurite peripheral nerves;
Inflammation of the language (glossitis);
Dryness and roughness of the skin on the face, especially around the eyes and lips;
Vertical and deep cracks on the lips;
Cracks in the angles of the mouth;
Numbness of the limbs;
Muscle weakness;
Reduced immunity by reducing the number of T-lymphocytes.

Symptoms of vitamin B 6 deficit in children

In children, vitamin deficit in 6 is manifested by the following symptoms:

Relief delay and physical development;
Convulsive attacks;
High convulsive readiness and convulsions;
Increased excitability;
Disorders of the digestive tract (meteorism, diarrhea, etc.);
Dermatitis with a pronounced inflammatory response.

Vitamin B 6 in products

Vitamin B 6 is contained in many foods. However, its largest amount is available in the following products:

Walnuts;
Hazelnut;
Potatoes;
White cabbage;
Sweet cherry;
Horseradish;
Yeast;
Sweet Bulgarian pepper;

The products listed above contain the maximum amount of vitamin B 6. Several in smaller, but also sufficient quantities of pyridoxine are contained in legumes (beans, beans, peas, fuck, lentils), fish, meat, dairy products, liver animals and birds, as well as croups and eggs.

Food rich in vitamin 6 - video

Daily rate of vitamin consumption in 6 people of different ages

The need for vitamin in 6 in children and adults is different because age features The functioning of the body. So, for children, the following daily rate of vitamin C consumption is adopted depending on the age:

Children from birth to six months - 0.1 mg per day;
Children 7 - 12 months - 0.3 mg;
Children 1 - 3 years - 0.5 mg;
Children 4 - 8 years old - 0.6 mg;
Children 9 - 13 years old - 1.0 mg.

Female and male teenagers, as well as adult men and women also have an unequal need for vitamin B 6. The daily needs in pyridoxine boys, girls, women and men are reflected in the table.

The above is the estimated average vitamin consumption standards per day, which should be performed daily. However, if during the week, a person will not be for a few days to lack Vitamin B 6 with food, and on other days, on the contrary, consume with excess, then dynamic equilibrium will not be disturbed due to overlapping, and in general the body will not experience the lack of pyridoxine.

The above rules are calculated for healthy people leading a moderately active lifestyle. However, with the nerve voltage, physical exertion, staying in the cold, working with chemicals and radionuclides The need for vitamin in 6 increases.

It is recommended to calculate the individual norm of pyridoxine consumption based on the amount of protein in the diet, based on the ratio: 0.032 mg of vitamin 6 per 1 g of protein. For diet nutrition Minimum enough level Pyridoxine consumption is 1 mg, and the maximum allowable is 6 mg.

In the treatment of various diseases, the dosage of vitamin in 6 by some clinician doctors is adjusted to 600 mg per day. Typically, such a dose is transferred without any negative consequences. However, scientists are recommended not to exceed the daily dosage of pyridoxine more than 50 mg.

Vitamin B 6 forms for medical use

Currently, Vitamin B 6 for medical application Produced in two dosage formsoh:
1. Tablets for receiving inside;
2. Solution for injection in ampoules.

Accordingly, Vitamin B 6 tablets are taken inward, and the solution is injected intramuscularly, intravenously or subcutaneously. With acne, a solution of vitamin B 6 is used externally in the form of a lotion and appliques for affected areas.

In addition to two dosage forms, the drug Vitamin B 6 for medical use may contain different vitamers as an active substance, such as pyridoxine hydrochloride or pyridoxal phosphate. The drug of vitamin B 6, containing pyridoxalphosphate as an active substance, has a faster therapeutic effect compared to pyridoxine hydrochloride. Otherwise, the properties of drugs with pyridoxine hydrochloride and pyridoxal phosphate are the same.

Vitamin B 6 - Indications for use

Vitamin B 6 is mainly used to eliminate and prevent hypovitaminosis or vitaminosis, as well as comprehensive treatment various diseases of the skin, nervous system, metabolism and rows of others. In addition, Vitamin B 6 is used in cosmetology in order to improve the condition of the skin, hair and nails.

A separate use of vitamin B 6 is prevention of hypovitaminosis in the treatment of tuberculosis with antibiotics. The fact is that anti-tuberculosis antibiotics consume vitamin 6 in large quantities, therefore, even against the background of its normal admission with food, a deficit state (hypovitaminosis or avitaminosis) can be created. Therefore, when using anti-tuberculosis antibiotics, it is necessary to additionally add vitamin 6. Currently, many new anti-tuberculosis drugs are available in a combined form, which includes an antibiotic and vitamin in 6. Such a combined form allows you to take only one drug and eliminates the need for additional and separate use of pyridoxine.

Today, general indications for the use of vitamin B 6 are the following states:

Early toxicosis of pregnancy with nausea and frequent vomiting;
Newborns on artificial feeding, produced by non-balanced specialized children's mixtures, and donor milk or milk of farm animals;
Newborns on artificial feeding, suffering from dryness, swelling and peeling of the skin;
Newborn with low body weight (hypotrophy);
Newborn with pyridoxin-dependent convulsive syndrome (hereditary disease);
Anemia combined with high concentration iron in the blood (hypochromic microcolist anemia);
People are low resistant to various infectious diseases;
People with increased excitability;
People of any age, including children suffering febrile convulsions (cramps that develop in response to high body temperature);
heart failure;
As part of the complex therapy of hepatitis and cholecystitis;
As part of complex Parkinsonism therapy;
As part of complex therapy of radiculitis;
Peripheral neurites;
Neuralgia;
Prevention of cramps during the course of use of fivazide;
Prevention of hypovitaminosis during the course of treatment with anti-tuberculosis antibiotics;
Defective nutrition;
Long-term infectious diseases;
To replenish the loss of vitamin B 6 with diarrhea;
Enteritis (for the prevention of hypovitaminosis against the background of impaired suction of pyridoxine through the inflamed intestinal wall);
Long stress;
Malabsorption syndrome;
States after removing the stomach or part of the intestine;
Little disease;
Alcoholism;
Dermatitis (atopic, seborrheic, acne, acne, etc.);
Herpetic infections (simple herpes, windmill, etc.);

As can be seen, the testimony for the use of vitamin B 6 is quite varied, due to the physiological effects of pyridoxine, which is literally exerted by each cell of any human body. That is why vitamin B 6 preparations are shown to use with so different states and diseases. Of course, with the help of only vitamin B 6, severe disease cannot be cured, but its use helps to increase the effectiveness of the therapy and, therefore, improve the forecast and course of pathology.

Vitamin B 6 in ampoules - characteristics and titles of drugs

Currently, a solution of pyridoxine hydrochloride of various concentrations is available in ampoules. Sterile solution and ready for use. For ease of use, the solution is marked not by the percentage of pyridoxine hydrochloride, but by the number of active substance in 1 ml. Today, vitamin solutions of 6 two concentrations are produced - 50 mg of pyridoxine hydrochloride in 1 ml and 10 mg per 1 ml.

The vitamin solution of 6 in ampoules is manufactured and sold under the following commercial names:

Pyridoxine (vitamin B 6);
Pyridoxine buffus (vitamin B 6);
Pyridoxin-Wiel (Vitamin B 6).

In addition to the specified monocomponent drugs, there is quite wide spectrum Polycomplete products that include several vitamins, including 6. These vitamins will be listed in a separate section.

Vitamin B 6 in tablets - characteristics and names of drugs

Currently, Vitamin B 6 tablets are produced, containing as active component pyridoxine hydrochloride. There are tablets with different content of pyridoxine hydrochloride - 2 mg, 5 mg and 10 mg. Vitamin B 6 tablets are sold under two commercial names:

Pyridoxine hydrochloride;
Pyridoxine (Vitamin B 6).

In addition, Vitamin B 6 is contained in the biologically active additive - autolysate of beer yeast. This BD is standardized, the amount of vitamins in it is accurately dosed, and their clinical effects are very pronounced. Therefore, as a source of vitamin B 6, you can use pharmacological preparations, and bad.

These drugs are monocomponential, that is, there is only one active substance - vitamin B 6. In addition to these monocomponent drugs, there is a wide range comprehensive toolscontaining several vitamins, including 6. A list of complex means containing vitamin B 6 will be reflected in a separate section.

Complex preparations with vitamin 6

Currently, complex drugs of vitamins intended for treatment and prevention containing several active substances simultaneously, including 6. These complex drugs can be divided into two large groups - prophylactic and therapeutic. Preventive preparations - This is vitamin and mineral complexes designed for periodic reception healthy people 2 - 4 times a year, and containing most of the 13 vitamins and several minerals. Examples of such complexes are Vitrum, Center, Supradin, Alphabet, Multi-TAB, etc. These drugs contain vitamin 6, but in addition to it, there is an even more than a dozen components. And since the preparations are accepted for the prevention of vitamin and mineralode deficiency, they are relating to the corresponding group.

Therapeutic drugs of vitamins contain several components - from two to five. Moreover, these components are selected for compatibility with each other and ease of use. For example, Vitamins 6 + in 12, which are very convenient for use, because they allow you to enter both connections in one injection. Such complexes contain vitamins in fairly large, therapeutic dosages and are used as part of the complex therapy of various diseases. And therefore, they are called therapeutic drugs. Below are a list of complex therapeutic preparations containing vitamin B 6:

Angovit (in 6, 12 + folic acid);
Binavit (in 6, in 1 and in 12 + lidocaine);
Biotrine (in 6 + amino acid threonine);
Vitagamma (in 6, in 1 and in 12 + lidocaine);
Vataxon (in 6, in 1 and in 12 + lidocaine);
Combiliphene (in 6, in 1 and in 12 + lidocaine);
Complies in (in 6, in 1 and in 12 + lidocaine);
Lizobact (in 6 + lysozyme);
Magvit (magnesium citrate + in 6);
Magne B6 (magnesium + in 6);
Magnelis B6 (magnesium lactate + in 6);
Magnesium plus B6 (magnesium lactate + in 6);
Medivitin (in 6, in 12 and folic acid);
Mexiya B6 (in 6 + ethylmethylhydroxypyridine succinate);
Milgamma (in 6, in 1 and in 12);
Milgamma composites (in 6 and 1);
Multi-tabs in complex (in 1, 2, in 3, in 5, in 6, 12 + folic acid);
Neurogamma (in 1 and in 6);
Neurobion (in 6, in 1 and in 12);
Neurulivitis (in 6, in 1 and in 12);
Pents (in 1, B3, in 6, 12 + folic acid);
Pizian (in 6 and in 12);
Polyneurine (in 6 and 1);
Trigamma (in 6, in 1 and in 12 + lidocaine).

Vitamin B 6 - Instructions for use

Vitamin B 6 can be administered injecting or take inside. Pricks can be done intramuscularly, intravenously or subcutaneously. When the injecting administration of vitamin B 6 cannot be mixed with in 1, since they are incompatible. Vitamins in 6 and in 1 need to prick in different days. However, in the pills of vitamins in 6 and in 1, it is possible to combine, since with this method of reception they are compatible.

The choice of the introduction method of vitamin B 6 depends on what is used for the drug. So, for the treatment of moderate hypovitaminosis or its prevention, as well as to improve the condition of the skin, hair and nails, Vitamin B 6 is recommended to be taken in the form of tablets. To eliminate severe hypovitaminosis or avitaminosis, as well as in the composition of the complex treatment of various diseases, vitamin B 6 is recommended to be used in the form of injections. Also, vitamin B 6 should be administered injectable if a person suffers with inflammatory or ulceated diseases of the digestive tract organs, under which normal absorption of the drug from the intestine is impossible.

The choice of a method of injecting administration (intravenously, intramuscularly or subcutaneously) is based on the possibilities of medical workers and patients. The most quickly, the drug begins to act with intravenous administration, which should be applied at acute states. In treating chronic pathologies If a person cannot attend medical institution for intravenous administration Vitamin B 6, he needs to go to intramuscular or subcutaneous injections At home.

Vitamin injection 6 - how to properly enter the drug

Intravenously, subcutaneously or intramuscularly introduced a ready solution in a dosage of 50 - 100 mg per day for adults and 20 mg - for children. The daily dosage of vitamin B 6 is broken into two injections that put in the morning and in the evening. Accurate dosage Vitamin B 6 is determined by the type of disease:

Therapy with anti-tuberculosis antibiotics is to introduce vitamin at 6 to 5 - 10 mg per day throughout the course of treatment;
Cideroblastic anemia - 100 mg per day, intramuscularly twice a week;
Parkinsonism is 100 mg per day, intramuscularly twice a week. The course of treatment consists of 20 - 25 injections. Repeated courses are carried out after the break in 2 - 3 months.
Depressed - 200 mg per day, intramuscularly.

The duration of the treatment course vitamin 6 for adults is one month, and for children - two weeks. Exceeding the specified time treatment time is not recommended, as this may lead to the development of heavy allergic reactions. If the treatment goals were not fully achieved during one full course, then a break should be taken for a month, after which it is vitamin in 6 repeated therapy. Repeated courses of treatment with interruptions between them at least one month can be repeated during an unlimited period of time, provided that a person tolerates the drug well.

The intramuscular injection is recommended to do in the side surface of the upper third of the thigh, and not in the buttock, since the injection into the muscles of the leg is much safer. To produce injections it is necessary to release outdoor surface The upper third of the hip from the clothes, wipe the skin in the area of \u200b\u200bthe injection center (alcohol, chlorhexidine, etc.), then gently break the tip of the ampoule with the solution, enter the tip of the syringe needle and dial the required amount of the drug into it. Then the syringe flush the needle up and knock on the surface of the tube in the direction of the piston to the needle, so that air bubbles take off from the walls and gathered on the surface of the solution. Then slightly press on the piston and release a few drops of the drug from the needle. After that, to introduce a quick and neat movement to the needle deep into the muscle, putting it perpendicular to the surface of the thigh skin. Slowly pressing on the piston, enter all the medicine into the muscle, then carefully remove the needle, holding the syringe is still perpendicular to the skin surface. Pitch place to rub an antiseptic.

Subcutaneous injection is best done on the forearms of the hands. Before the prick should wipe the skin with an antiseptic and gain medicine into the syringe. Release a drop of solution from a syringe to remove air, and close the needle with a lid. Finished syringe put on a clean surface in such a way that it was possible to reach it to it. Then with the left hand to assemble the skin section 1 - 1.5 cm and retain it in this way until the end of the injection. Right hand Take a syringe, remove the cap and enter the needle under the fold of the skin, holding it parallel to the bone of the forearm. Slowly introduce the entire volume of the solution and remove the syringe, continuing to hold the left hand of the skin fold. After the needle is removed, you can let go of the skin and wipe the place of the injection by an antiseptic.

Intravenous injections are not recommended independently, because without proper skill it is dangerous and hurt. For intravenous administration of vitamin B 6, you should use the services of a professional nurse.

Instructions for use of vitamin 6 inside

Pyridoxine tablets must be taken after eating, not chewing and drinking with a small amount of water. For the prevention of hypovitaminosis, adults are recommended to take 2 - 5 mg per day, and 2 mg to children per day. For the complex treatment of various diseases, Vitamin B 6 must be taken at 20 - 30 mg per day. The daily dosage of vitamin B 6 can be taken once or split into two receptions - in the morning and in the evening. The duration of preventive and therapeutic reception of vitamin B 6 is 1 to 2 months for adults and children.

Vitamin B 6 - Application for various purposes

Vitamin B 6 for hair

Vitamin B 6 for the hair is very important because it strengthens, prevents and prevents their loss. With vitamin deficiency, the hair falls out, the head of the head is inflated, dandruff appears and itch.

Mask with vitamin 6 for hair

The solution of vitamin B 6 at a concentration of 50 mg / ml volume of 1 ml is added to the cooked homemade or purchased hair mask and thoroughly mix the mass. This amount of solution is added to the amount of mask, which will be used for one application on the hair. Each time before using a mask, 1 ml of vitamin solution of 6 should be added to it. At the same time, you can cook or buy any masks that you seem helpful. Before use, you must consult with a specialist.
Vitamins for leather - properties and physiological effects, characteristics and reviews of vitamin preparations

Vitamin B1 (thiamine) is a physiological role, symptoms of deficiency, content in food products. Instructions for use of vitamin B1

Vitamin B6 is very important for the proper operation of the body.

Its disadvantage or overdose badly affect the work of the body

This substance was opened in 1934 by the Hungarian doctor of the Giorgi field. Water soluble vitamin, cured dermatitis in rodents, he called B6. Over time, it turned out that this is not one substance, but a whole group that includes pyridoxine, pyridoxamine and others.

All of them are interrelated and work in the complex. In the body, they are transformed into a single form - peroxual phosphate, which protrudes with the catalyst for many metabolic reactions.

Basic functions B6.

Required for amino acid synthesis
Participates in the exchange of lipids and macroelements
Without it, the formation of red blood cells and antibodies does not occur, so it is taken with anemia and reduced immunite
It plays an important role in the formation of neurotransmitters involved in the transfer of nerve impulses: serotonin, adrenaline, etc. That is why vitamins B6 are shown in the diseases of the nervous system - from ordinary stress to Parkinson's disease.
Important for the proper work of the liver
Natural diuretic
Treats skin disease
Removes nausea, so used when swinging and toxicosis of pregnant women
Helps with muscle spasms at night and numbness

Feature! Vitamin B6 is needed for those who consume many protein products - athletes and physically active people, since it is involved in the synthesis of protein and muscle growth, increases the health effect, has a diuretic effect.

Now, knowing the role of this vitamin for the full work of the body, it becomes clear how important it is to take it in sufficient quantities.

Fortunately, this wonderful substance is widespread, it can be found in large number of products both vegetable and animal origin. The most rich for them:

cereals (and the most of all it is contained in shells and germs of seeds, so it is best to use bran, brown rice varieties, bread and pasta of coarse grinding flour);
brewer's yeast;
nuts (especially walnuts and hazelnuts);
sub-products (heart, liver, kidney);
fish (especially tuna, salmon and cod);
eggs;
milk products;
spinach, cabbage, tomatoes, asparagus, legumes.

In addition, Vitamin B6 is synthesized in the organism of the intestinal microflora.

Daily rate (table)

Vitamin B6 dosage directly depends on age. Average daily dose Adult man 1.5 - 2 mg per day.

The need for it increases from suffering nervous diseases, pregnant and lactating women, athletes in the period of increased loads. In such situations, it can be taken up to 4 mg per day, and with very intense loads - up to 10 mg.

How much taking vitamin B6 depending on the age and condition of the body is indicated in the following table:

These norms are desirable not to exceed independently, otherwise various violations may occur in the body's work.

Contraindications of taking vitamin B6

For most people, he is perfectly learned without causing any unpleasant consequences. Nevertheless, sometimes the individual intolerance to this useful substance is found. Such people may have allergic rashes on the skin, for example, urticaria.

Reception of synthetic forms of vitamin B6 is limited or not recommended for patients suffering ulcerative disease Gastrointestinal tract, heart and liver diseases.

Symptoms overdose

As a rule, Vitamin B6 is well absorbed, and in case of excess - perfect excreted with urine for 8 hourswithout accumulating in the body. But in some cases an overdose is possible, which is manifested by the following symptoms:

allergy;
skin problems (dermatitis, urticaria);
anemia and worsening blood circulation;
violations by the nervous system - headaches, decline in attention, disruption of sensitivity and tingling limbs;
night cramps;
deterioration of coordination;
an increase in the acidity of gastric juice;
reducing milk generation in nursing mothers.

In the case of receiving large doses of vitamin, which happens during injection, it is often arising from hand and legs. In the case of severe allergies or very large doses, anaphylactic shock is possible, which happens rarely. In chronic overdose, the loss of proteins in the tissues may occur internal organsWhat leads to a violation of their work.

Interesting! Interesting and pretty a characteristic symptom Strong overdose are very bright nightnamies, memorized in all details.

All these symptoms disappear if you stop the additional reception of vitamin B6. Excluding from diet products containing this substance should not.

Causes of overdose

As already mentioned, Vitamin B6 is very well excreted from the body with urine, so hypervitaminosis is possible only in rare cases. It occurs:

in people suffering from hypersensitivity to this substance;
if you take it too long in large doses that the body does not have time to remove (this is characteristic of athletes and people actively engaged in sports halls - as a rule, men who are fond of bodybuilding);
in the case of rapid intravenous injections.

IMPORTANT!Sometimes an overdose is found in children who have come to bubble with vitamins. Parents should be remembered that vitamins are useful only in strictly defined quantities. The daily rate of consumption of vitamin B6 for children should not exceed 1-1.7 mg (details above).

In addition, you need to know that any synthetic vitamins - in pure form or in the composition vitamin complexes - It is worth taking after consulting a doctor. Only a knowledgeable specialist after the relevant studies can estimate the need of the body in a particular substance.

To exclude possible hypervitaminosis, Vitamin B6 is best taken in its natural form, eating products containing it in large quantities.

Side effects of drugs with vitamin B6

Some of the available multivitamin complexes contain a very high dosage of vitamin B6. This is especially true of the dietary supplements used by athletes and people actively engaged in the gym, to increase muscle mass.

On the early stages side effects manifest in the form of allergic reactions. Such drugs should be taken with caution, do not exceed the recommended dose and take breaks.

Vitamin B6 and Magnesium

Vitamin B6 works very well in a pair with magnesium. They improve assimilation and strengthen each other's action. In the case of taking such drugs, the B6 overdose does not occur.

Conclusion

Vitamin B6 so important for normal metabolism And the proper work of the nervous system. Often the body is experiencing a shortage of this beneficial matter. Especially often it happens with increased physical exertion and overloads of the nervous system.

In this case, its additional reception is needed, but it is desirable only after consulting a doctor. After all, the overdose of vitamin B6 can cause no less unpleasant consequences than its deficiency.

In contact with

Vitamin B6 is also called Aermin or Factor Y (old names that were used when opening and primary learning for which it is needed by the body).

This is the general name of the chemical compounds that manifest the activity of pyridoxine: pyridoxal, pyridoxine and pyridoxamine. Otherwise, they are called "Vitamers B6", which are of great importance in the proper nutrition of a person to ensure the normal functioning of many organs and systems.

Vitamin B6 - what is his role in the body, for which it is responsible and in which products is contained.

The discovery history of the substance can be divided into 3 stages:

1934 - the discovery of a new substance in the study of yeast drugs;
1938 - A substance that contributed to the cure of symmetric dermatitis is isolated from yeast and rice bran. A new chemical compound was called Aermin;
1939 year - The structure of the substance is determined, it received the name of pyridoxyl (pyridoxine).

Physiological role

Vitamin B6 and why he needs a body - the main question in a scientific study. Finding into the human body, as a result of multi-stage reactions, Vitamers B6 are converted into pyridoxalphosphate - an integral part of many enzymes catalyzing the most important processes of assimilation and dissimulation.

They are as follows:

hemoglobin synthesis;
histamine;
lipid and carbohydrate exchange;
stages of protein synthesis, during which hereditary information from the gene is transformed into RNA or organism protein.

Hormones and neurotransmitters are synthesized with its participation: adrenaline, norepinens, serotonin, dopamine, amine-oil acid.

Physiological role:

Properties of any organism are determined by those proteins from which it is built. The unit of the structure of any protein is amino acids. Some of our organism is able to create himself, many we get along with food. The most important property of amino acids is intertwined. That is, if the body is currently lacking for the synthesis of some particular amino acid, it can be created from another available in excess. It is the process of mutual transition of amino acids starts and regulates pyridoxine.
This substance contributes to a better suction of chemical compounds of food with a small intestine and transfer them to cells and tissues.
Ensuring the livelihoods of cell cells is carried out thanks to ATP. It is the adenosine trifhosphate cells that use as an energy depot. The staircase of the reaction, which results in the synthesis of ATP in mitochondria and plastids, is called the Krebs cycle. The course of this multi-stage process, as a result of which ATP is synthesized from carbohydrated organisms, occurs under the control of pyridoxine.
The main property of nerve cells is the ability to be excited. The excitability of the CNS requires the opposite - braking. Exaltation, convulsions - the result of excessive initiation and lack of braking in the department of the central nervous system, occurs with insufficient admission of pyridoxine into the body. The excitation of neurotransmitters is evacuated: serotonin, gamc (gamma-amine-oil acid), which are products of decarboxylation reactions. This reaction passes with the participation of pyridoxine. For the body, it is the coordinator of the normal operation of the spinal and brain.
Thanks to Pyridoxin, the body synthesizes more protein of sederophiline, which carries iron from the intestine to the bone marrow. It is he who is a blood formation organ. The iron is required to create hemoglobin, which is part of the red blood cells. It provides transport on the bloodstream of oxygen and carbon dioxide.
B6 increases the production of succinic acid and norepinephrine, increasing the metabolic rate: cells are updated energetically, rejuvenating organs.

Physical and chemical properties

Pyridoxine and all its derivatives have a number of similar physical signs.

Chemical properties are determined by the presence of aldehyde (or amine) and alcohol group:

What is needed pyridoxine organism

Vitamin B6 and why it is needed by the body, is being studied relatively long. But now, medical statistics says that more than hundreds of diseases and disorders begin with a deficiency of pyridoxine. And every sixth on the planet is experiencing this deficit. Listing all the problems arising in hypovitaminosis B6 is impossible.

The human body with it is due to the situation of essential processes and the prevention of heavy diseases:

transaminase synthesis in the liver for a full protein metabolism;
the exchange of lipids, which is very important for the prevention of obesity and maintain the structure of cell membranes;
the exchange of carbohydrates, so that the blood level is regulated in the blood;
beneficial effect on the body of vision;
prevention of blood clots;
optimization of blood pressure;
a diuretic action helps to remove excess fluid from the body, removing the edema on the face and limbs;
reducing the risk of oncological diseases;
with his participation, neurotransmitters and joy hormones are produced, which has a positive effect on the CNS and life activity as a whole;
the possibility of the formation of stones in the bustling bubble and renal loching is reduced;
prevention of the lesions of the cardiovascular system: ischemia, atherosclerosis, heart attack;
maintaining and improving immunity;
the qualitative absorption of magnesium and cobalt tissues in the composition of vitamin B12, as well as the synthesis of hydrochloric acid.

Separately, it should be noted the importance of pyridoxine for the female organism. This vitamin supports the balance of sex hormones, reducing the risk of neoplasms. It must be taken to women using hormonal contraceptives, as they significantly reduce the level of vitamin in the blood.

During pregnancy and before menstruation, when the estrogen level increases, it is also necessary to replenish the amount of pyridoxine. Of course, the beauty of hair and skin plays an important role for women, the healthy appearance of which directly depends on the sufficient intake of vitamin B6.

Vitamin B6 for bodybuilder

Vitamin B6 and why he need a bodybuilder's body is not a secret: the primary task of an athlete is the formation of muscle mass. Muscular fabric is built of protein. Since Pyridoxin regulates protein synthesis processes, then this vitamin must be used in bodybuilding.

Training requires a great return of forces, so enzymes and hormones, which are formed in the body with vitamin B6 participation, increase the endurance of the body and stimulate metabolic processes.

Pyridoxin in cosmetology

Pyridoxine is the main vitamin group in, which supports the health of the skin and its derivatives: hair and nails. To achieve a resistant effect, the use of externally preparations with vitamin combines with the use of vitamin rich.

With a lack of pyridoxine in the body, it is observed:

When such symptoms appear, it is worth thinking about replenishing the lack of vitamin in the body.

In cosmetology, a variety of skin masks and its derivatives are used with the addition of pyridoxine and its analogues. Competent and regular use of vitamin B6 helps to put in order the scalp and face skin, hair quality and nails, normalize weight and adjust the figure.

For example:

In the late 1970s, American nutritionists have developed a "wonderful" diet, which took possession of the minds of overweight suffering. The main secret of the magic diet consisted in much greater than the usual daily rate, the number of vitamin B6. In aggregate with apple vinegar, linen seed and soybean oil, he gave a wonderful effect of burning excess adhesive tissue.

Toxicity of vitamin B6 and contraindications

Pyridoxine and its analogues are not toxic substances. Even a long-term use of vitamin as a therapeutic agent did not cause a negative reaction from the body. Studies were conducted in various ways of introducing animals and human and human-concentrations of pyridoxine for a long time. In some cases, allergic reactions may occur .

With caution, you should approach Pyridoxin's reception to people with gastric diseases (gastritis, ulcers) and other gastrointestinal departments, as pyridoxine increases the percentage of acidity. The appointment of vitamin with heavy lesions of the liver and ischemic disease is contraindicated.

Daily norms of vitamin for different groups of people

Floor	Age, years	Vitamin rate, mg
children	0-1	0,3-0,6
children	1-10	1,0-1,4
boys	11-14	1,7
men	16-59	2,0
men	older 60.	2,2
girls	11-14	1,4
girls	15-18	1,5
women	19-59	1,6
women	Older 60.	2,0
pregnancy period		2,2
period of breast feeding		2,1

Suction and elimination of the body

The blood flow is spreading pyridoxine and its derivatives to the tissues from the small intestine, which is allowed to absorb the sprawling products of the federation. The accumulation of vitamin cells does not occur, therefore the body needs its constant admission to food.

The whole pyridoxine falling into the body or is used for the needs of the body, or is displayed with urine through the kidneys. Partial removal of pyridoxine is observed through the skin with a secret of sweat glands.

Vitamin B6 digestibility and conservation methods

Vitamin, as all water-soluble compounds, is well absorbed by the body, penetrating freely through cell membranes.

The simplest replenishment of vitamin is the use of products rich in the content of this substance. Unfortunately, various preparation methods (thermal processing, preservation) are destroying for chemical compounds, and a significant amount of vitamin disappears.

Preservation "eats" to 50-70% pyridoxine, frost takes about 40% in products, and the temperature effect destroys vitamin B6 by 80-90%.

Therefore, it is useful to eat more raw vegetables and fruits in food, Add branches and seedlings of cereals to the diet, eat nuts, use yeast when baking. Thermal impact can be "mitigated" by steam treatment (instead of frying) or wrapping the baked product in foil.

Vitamin B6 deficiency in the body

Vitamin B6 and why it is needed by the body, is described above.

Therefore, it is obvious that the lack of pyridoxine has consequences more serious than overdose:

Pyridoxine deficiency in children is manifested in the form of general weakness, muscle pain and spasms, numbness numbers, girls - premenstrual syndrome.

Excess pyridoxine and overdose symptoms

Permissible norms of daily intake of vitamin B6 - 50-100 mg. With a long overdose (increase in the dose of 50-100 times) in a few years a state of hypervitaminosis develops, which may have unpleasant consequences.

They are as follows:

convulsions;
dizziness;
nausea;
skin rash;
numbness of lips, hands and legs;
anemia;
fainting;
coordination violation;
oppression of the lactation process;
accurate and detailed memorization of dreams.

Such phenomena is extremely rare, since Vitamin B6 does not have tendency to accumulate, and its excess is quickly removed from the body with urine.

The symptoms of overdose disappear soon, for which it is necessary to stop the reception of pyridoxine preparations.

Indications for use

List of readings:

Vitamin B6 sources

Aermin (vitamin B6) is one of those that are synthesized by the bacterial microflora in the fat intestine of a person.

Pyridoxine is absent in plant organs, or is contained in minimal quantities. Just this form of Adermina Pighta - edible fruits of cacti. It is contained in dairy products and in meat. Quickly destroyed during heat treatment, so in the cooked meat it almost does not remain. Vegetarians should use vegetables, whose covers in contact with the earth (carrots, beets, potatoes, turnips).
Pyridoxal sources are cabbage of any variety, meat and green parts of some edible plants.
Pyridoxamine can be obtained from animal muscle fibers and birds.

Products (Plants)	MG / 100 g	Products (animals)	MG / 100 g
sage (Grass)	2,69	tuna (Fish)	0,8
pistachios (fruits)	1,5	mackerel (Fish)	0,8
wheat bran	1,3	salmon	0,8
sunflower (seeds)	1,34	liver (beef)	0,7
garlic	1,23	sardine	0,7
mayran (Grass)	1,2	pink salmon	0,6
beans, Soy (Seeds)	0,9	keta	0,5
sea buckthorn (fruits)	0,8	kidneys (beef)	0,5
walnut Walnut (Fruits)	0,8	heart (beef)	0,5
sent (seeds)	0,79	poultry Meat (Kura)	0,4
funduk (fruits)	0,7	sturgeon caviar (black)	0,46
horseradish (root)	0,7	rabbit (meat)	0,48
rice (grain)	0,54	egg chicken (yolk)	0,46
pepper sweet (fruit)	0,5	meat (lamb)	0,3
pepper sharp (fruit)	0,5	herring	0,3
millet (cereals)	0,4	cheese (Roquefort)	0,15
grenade (fruits)	0,4	condensed milk)	0,13
cashew	0,42	cheese (Poshekhonsky)	0,13

Rice, pshlin or buckwheat porridge for breakfast satisfies the daily need of a person in pyridoxine. It is better if porridge and salads are refilled by vegetable oil, which is rich in vitamin B6. It is recommended to incorporate fresh fruits and vegetables in the diet daily (lemon, strawberry, cherry, bananas, tomatoes, cabbage) and freshly prepared juices.

Vitamin B6 in ampoules

Pyridoxine in ampoules is sold in pharmacies under different names.

Preparations have identical composition and differ only on the manufacturer's name:

In addition to use for injections, vitamins in ampoules are used in cosmetology. Liquid pyridoxine is much more convenient to add to shampoos and cream than grinding tablets or dissolve powders. Reception of such a form of vitamin of the orally desired effect does not bring.

Vitamin B6 in tablets

Most often, pyridoxine is appointed in the form of tablets (capsules, dragee), which is convenient to take. They are quickly and easily absorbed by the body. Monovitamins are preparations that contain pure pyridoxine and are used to treat the acute shortage of vitamin.

There are such as:

Pyridoben.
Pyridoxine hydrochloride.
Bartel Drags Vitamin B6.
Vitamin B6.
Pyridoxin-N.S.

In addition, Vitamin B6 is included in the multivitamin complexes appointed for the prevention in the autumn-winter time, with a reduced immunite.

They are:

All drugs are interchangeed, use them after feeding in a dose defined by the doctor, or specified in the instructions.

The appointments of therapeutic and prophylactic differ significantly in the number and timing of the reception. You can focus on the instructions only when used to prevent prevention. In other cases, the course of reception is determined by the doctor.

There are numerous mineral-vitamin preparations, such as complivit, alphabet, multi-tabs, center, vitrum, which can be used independently to maintain immunity in different periods of life.

Vitamin B6 injections

The intramuscular or intravenous use of preparations with pyridoxine is prescribed in cases where for some reason, the reception of the tablets is impossible or inffective.

Cases are as follows:

Therapy requires a significant dose of vitamin, which cannot be absorbed through the gastrointestinal organs when taking tablets and should be included in the bloodstream. For example, in diabetes, some poisoning, disorder of the hematopoietic function, diseases of the musculoskeletal system.
A person is unable to take pills. The reason for this may be mental disorders, fainting, vomiting, connecting to the apparatus of artificial respiration.
Violations of the operation of the gastrointestinal tract, in which the normal absorption of the drug does not occur. Such phenomena may be a consequence of operations, ulcerative disease, defects of the epithelium of the small intestine.

It is possible to note the soreness of injections with pyridoxine. To reduce pain in drugs for injection include lidocaine.

Interaction with other substances

It is necessary to achieve better assimilation by the body of pyridoxine (vitamin B6) to achieve the maximum healing effect, for which you need to remember the interaction of drugs and their mutual influence on each other.

For example: