A drug with antibacterial, antifungal and hemostatic action for local application in ENT practice and dentistry

Active substance

Release form, composition and packaging

◊ Topical spray 0.2% in the form of a transparent, colorless or almost colorless liquid with a specific odor.

Excipients: methyl salicylate - 6.7 mg, anise essential oil - 14 mg, essential - 4 mg, essential orange blossom oil - 3.3 mg, essential sassafra oil - 3.3 mg, peppermint essential oil - 23.1 mg, levomenthol - 6.7 mg, sodium saccharinate monohydrate - 8.3 mg, glycerol 85% - 7.6598 g, ethanol 96% - 19.3877 g.

30 ml - polyethylene bottles (1) with a spray and an applicator - cardboard boxes.
30 ml - bottles made of polyethylene terephthalate (1) with a spray and an applicator - cardboard boxes.

pharmachologic effect

Antiseptic for topical use in dentistry and ENT practice. It also has antifungal activity and analgesic effect when applied to the mucous membrane. In addition, it has an enveloping effect.

The duration of the action is 10-12 hours.

Pharmacokinetics

Data on the pharmacokinetics of Stopangin are not available.

Indications

- infectious and inflammatory diseases of the oral cavity and larynx (tonsillitis, including Vincent, pharyngitis, stomatitis, aphthous oral ulcers, glossitis, periodontitis, bleeding gums);

— fungal diseases (candidiasis) of the oral cavity and larynx before and after surgical interventions on the oral cavity and larynx;

- trauma to the oral cavity and larynx;

- prevention of infection of the alveoli after tooth extraction;

- oral hygiene to eliminate from the mouth (deodorant);

- prevention of superinfection with destructive tumors of the oral cavity and larynx.

Contraindications

- atrophic pharyngitis;

— childhood up to 8 years old;

- hypersensitivity to drug components.

Dosage

The spray is used 2 times / day (unless the doctor has prescribed otherwise), after meals or in the intervals between meals.

Before use, remove the protective cap from the bottle and attach the applicator. Press 2-3 times to get the solution into the sprayer. Then hold your breath and sprinkle onto the affected area. After use, the applicator should be rinsed with warm water.

The duration of treatment with Stopangin is 5-7 days.

Side effects

Local reactions: a burning sensation of the mucous membrane of the oral cavity (quickly passes spontaneously).

Others: in exceptional cases, allergic reactions are possible in patients with hypersensitivity; if the drug is accidentally swallowed when rinsing, nausea is possible (passes spontaneously).

Overdose

Cases of drug overdose are unknown.

Drug interactions

The drug interaction of the drug Stopangin is not described.

special instructions

The patient should be warned about the need to consult a doctor in the following cases: when unusual reactions occur when using the drug; with a deterioration in well-being, an increase in body temperature, ineffectiveness of medical procedures; if necessary, the simultaneous use of Stopangin with other drugs; in case of an overdose.

The spray should not be inhaled; contact with the eyes should be avoided.

The expediency of the simultaneous use of the drug Stopangin with other drugs is determined by the doctor.

Without consulting a doctor, the drug can be used no longer than 5-7 days.

Use in pediatrics

Stopangin in the form of a spray can only be prescribed children over 8 years old and only in cases where possible correct application the drug (the child does not resist the applicator in the mouth, and should be able to hold his breath at the time of the spray injection).

Parents should be warned that if a child accidentally took the drug by mouth, they should consult a doctor.

The product contains 62% ethanol.

Influence on the ability to drive vehicles and use mechanisms

Patients taking Stopangin should refrain from driving vehicles within 30 minutes after its use.

Pregnancy and lactation

The drug is contraindicated for use in the first trimester of pregnancy.

It is possible to use the drug in the II and III trimesters of pregnancy and during lactation ( breastfeeding).

Childhood use

The drug Stopangin in the form of a spray can only be prescribed children over 8 years old and only in those cases when the correct use of the drug is possible (the child does not resist the applicator in the mouth, and must be able to hold his breath at the moment of injecting the spray). Parents should be warned that if a child accidentally took the drug by mouth, they should consult a doctor.

Terms of dispensing from pharmacies

The drug is approved for use as a means of OTC.

Storage conditions and periods

The drug should be stored in a dark place at a temperature of 10 ° to 25 ° C; do not freeze. Shelf life is 2 years.

Complex of some essential oils (sassafras, peppermint, aniseed, orange tree, eucalyptus), as well as auxiliary components such as saccharin, ethanol.

Release form

The medicine is available in the form spray (transparent, almost colorless or colorless liquid with a special odor), as well as in the form solution with a specific odor, possibly with a slight sediment.

pharmachologic effect

Stopangin solution and spray provide antiseptic action .

Pharmacodynamics and pharmacokinetics

The main component of the drug is hexetidine - is antiviral, fungicidal and antibacterial agent. It also has a slight anesthetic and coating effect. Hexetidine replaces thiamine , promoting the growth of bacterial flora, which determines the antibacterial effect of the drug. Moreover, this active ingredient prevents the synthesis of substances that create a protective shell of fungi.

Methyl salicylate reduces enzyme action cyclooxygenase stimulating the flow to the affected areas and accelerating their recovery, as well as exerting a local irritant and anti-inflammatory effect on the mucous membranes.

Combination essential oils the drug has a mild antibacterial and anti-inflammatory effect, and also reduces the feeling of discomfort when coughing.

The effect of the drug lasts about 11 hours. All components are removed from ... They do not enter the general bloodstream and are evenly distributed on the mucous membrane of the pharynx and mouth.

Indications for use

The medicine is used for:

• need to eliminate ;
• infectious and inflammatory diseases, fungal diseases and injuries that occur in the larynx and oral cavity;
• prevention alveolar infections after ;
• prevention of superinfection with destructive tumors of the larynx and oral cavity.

Contraindications

Side effects

Stopangin may cause sensation for a while in the mouth. In addition, with individual intolerance to its components, it may occur, including laryngospasm or bronchospasm ... If the drug is accidentally swallowed, a temporary feeling of nausea may appear.

Instruction for Stopangin (Method and dosage)

For those who decide to apply spray StopanginThe instructions for use recommend using it 2 times a day. It is advisable to do this after meals or between meals.

Before using the product, you need to remove the cap and then attach the applicator. At the beginning, 2-3 clicks should be made so that the solution is in the sprayer. Before use, it is better to hold your breath and then sprinkle on the affected area. After the procedures, the applicator must be rinsed in warm water.

The instruction for Stopangin provides for the duration of use of the drug for a maximum of 5-7 days.

Solution use undiluted, it serves as a mouthwash. Apply 10-15 ml (1 tablespoon) for at least half a minute 2 times a day. In addition, children and adults can lubricate the oral mucosa with a cotton swab on a stick.

The solution is applied after meals or in between. The duration of treatment is maximum 5-7 days.

Overdose

Overdose cases with this drug are not known.

Interaction

Stopangin's drug interactions have not been described.

Terms of sale

The drug is sold without a prescription.

Storage conditions

It is necessary to store Stopangin at temperatures up to 25 ° C, out of the reach of children and well protected from the sun's penetration in the best place.

Shelf life

The maximum shelf life of the drug is 2 years.

Stopangin during pregnancy and lactation

Stopangin is contraindicated for use during the first trimester. However, with close supervision by a specialist, you can use it in the second and third trimester, as well as with breastfeeding.

Stopangin: instructions for use and reviews

In the treatment of throat diseases, Stopangin spray is often used. Instructions for use and doctors' reviews call it an effective remedy with almost complete absence of side effects. And what do the patients themselves think about this? Can the drug be used during pregnancy? Are there analogues that are cheaper? Let's figure it out.

When is the spray prescribed?

A sore throat can be a symptom of both common hypothermia and a more serious health problem. As a rule, it accompanies acute respiratory diseases and the flu. To remove pain sensation in pediatrics and adults, Stopangin is often prescribed. The doctors' comments indicate that the spray quickly and effectively relieves inflammation and facilitates the swallowing process.

The indications for prescribing a spray are:

• viral, bacterial and fungal diseases of the throat;
• candidiasis of the mucous membranes of the larynx, in other words, thrush;
• prevention during the period of influenza and ARVI.

IN postoperative period the drug is used for antiseptic treatment of the throat and oral cavity, including after dental procedures.

In all these cases, "Stopangin" is not an independent drug for treatment, but is used only in complex therapy diseases.

Manufacturer, release form and storage conditions

Spray "Stopangin" (reviews of those who used it for treatment, we will consider below) is available pharmaceutical companybased in the Czech Republic, Ivex Pharmaceuticals.

"Stopangin" for topical application in the form of a spray is available in 30 ml vials, which are in a cardboard box. Complete with Stopangin spray (instructions and reviews confirm this) there is a special nozzle for spraying the drug. Doctors strongly recommend not to use it at the same time in people with different diseases and for preventive purposes in order to avoid infection.

The drug should be stored in a dark and dry place, at a temperature not exceeding 25 degrees. It is also necessary to control that it is not accessible to children. You can use the drug for no more than two years from the date of release, but doctors advise not to use the unopened bottle for more than six months, as loss is possible medicinal properties "Stopangin". Patient reviews fully confirm this.

Composition of the medicine

"Stopangin" has a rich composition, which determines its high efficiency in the treatment of many throat diseases of various etiologies.

As the main active substance Hexetidine acts, it is 57.7 mg in the spray. But this is not the only substance that has a pronounced therapeutic effect... The product also includes:

• Peppermint... Her healing properties were known in Ancient Greece and were described in the writings of famous healers of the past: Avicenna, Hippocrates and Paracelsus. Mint has a pronounced antiseptic, bactericidal and anti-inflammatory effect. Used in the treatment of diseases of the upper respiratory tract and as prophylactic during the period of acute respiratory infections. Compresses based on it are used to relieve fever for colds.
• Anise essential oil... Is pretty potent substance, therefore, it is prohibited for use during pregnancy. Reviews of "Stopangin" indicate that doctors rarely prescribe medicine women who are carrying a child. Beneficial features anise oil are emollient, expectorant and antipyretic effects on the human body.
• Sassafras oil... It is used in the preparation as a local antiseptic.
• Orange tree essential oil... In addition to antiseptic and anti-inflammatory properties, it has an effective effect on immune system person. It is also an excellent antispasmodic and pain reliever.
• Eucalyptus tree oil... The aborigines did not call eucalyptus the tree of life for nothing. In the treatment of respiratory diseases, its properties are difficult to overestimate. In addition to being anti-inflammatory and antiseptic, this tree oil makes breathing easier and general state the patient. Cineol, which is part of it, also has an antiviral effect. This is why eucalyptus oil can be found in many medicines that are prescribed to treat influenza and SARS.

Also, as auxiliary components in the spray there is sodium saccharinate monohydrate, methyl salicylate, ethanol and glycerol.

Could there be negative consequences?

Usually, side effects - This is a rare occurrence after the use of the drug "Stopangin". Reviews and instructions for use describe the following manifestations:

• Occasionally there is allergic reactions, this may be due to individual intolerance to any of the components of the drug. In this case, doctors recommend stopping the use of "Stopangin" and replacing it with another agent with different components.
• A feeling of slight burning and dryness of the mucous membranes of the throat is possible. As a rule, such sensations disappear very soon and do not pose a threat to the health of patients.
• If you accidentally swallow a small amount of the medicine, nausea and vomiting are possible, so use the spray as carefully as possible.

Is it always possible?

The drug "Stopangin" is not always prescribed for the treatment of throat diseases in the form of a spray. And in some cases, its use is, in principle, contraindicated.

In the first trimester of pregnancy, doctors never prescribe Stopangin. For children (parents' reviews confirm this) under the age of 8 years, the use of the drug in the form of a solution is recommended. It is just as effective as a spray. With the help of a cotton swab, it is applied to the affected mucous membranes of the tonsils. But the solution cannot be used in babies under 6 years old. Also, a contraindication to the use of the drug is atrophic pharyngitis.

The spray does not affect concentration, so it can be used while driving vehicle... The only thing, since the composition includes ethanol, it is recommended to irrigate the oral cavity half an hour before the planned trip.

IN clinical practice no cases of overdose with Stopangin have been officially recorded.

How to use and how much?

In order to get the expected result from the use of any drug, you must strictly follow the rules that are described in the instructions for use. Reviews of "Stopangin" (we will present analogs of the drug below) are advised not to violate the frequency of use in order to avoid side effects.

The drug is applied by spraying to each tonsil. This should be done after meals and in between meals. If the specialist has not prescribed another course of use, the procedure for treating the throat with the drug is carried out no more than 3 times a day. During the injection of the product, you need to hold your breath.

Avoid getting the medicine on the mucous membrane of the eye. If this does happen, you need to rinse your eyes with warm water and seek the advice of your doctor.

Issue price

The drug "Stopangin" can hardly be called budgetary, and in many respects negative reviews are associated with the overestimated cost of the drug (according to the consumer). A bottle of the product will cost about 270 rubles and more (depending on the region and the pharmacy chain).

Not everyone can afford this spray, given that it is not prescribed as an independent medicine, but only in complex treatment diseases. Therefore, many people have a very natural question: is it possible to find a less expensive tool, but at the same time, the same effective?

Will it be cheaper?

Of course, Stopangin (reviews confirm this information) has analogues that are cheaper. Not all of them are as effective, but they can be treated if necessary.

The very first medicine that patients and doctors advise to pay attention to is Hexoral. This is a complete synonym for "Stopangin". It is produced by the American company Pfizer. The price of "Geksoral" is about 230 rubles. It can be used after 3 years in a child, as well as during pregnancy and lactation, but only after consulting a doctor. The consumers did not notice any special differences in the preparations, the only thing is that "Hexoral" is a little cheaper.

"Maxicold Lor" is a drug in the form of a spray, which in its composition contains all the same active ingredient - hexetidine. It is produced in Russia and will cost the consumer about 150 rubles per bottle. Can be used from 3 years old, as well as women in position and nursing mothers. Many patients have noted its effectiveness in treating sore throat. Some argue that the result after using Maxicold comes much faster than after Stopangin.

What else can replace Stopangin? Reviews recommend paying attention to the following medications in the form of a spray:

• "Hepilor" - about 160 rubles. for a bottle of 20 ml.
• "Angilex" - 150 rubles.
• "Givalex" - 190-200 rubles.
• "Grippocitron Lor" - about 140 rubles.

Some patients tried to use Lugol in the form of a spray for throat treatment, but were disappointed with the result. Although it costs much less, it is not as effective as Stopangin.

Consumer verdict

Many who have left their feedback on the quality of Stopangin and its analogues claim that all sprays based on hexetidine do a good job with their task. Sore throat disappears, inflammation is relieved, there are practically no side effects.

Some cases of negative opinions relate more to the price of the product than to its quality. But here it should be noted that no one promised that a good medicine would cost a penny. So, in the end, everyone decides for himself which drug to choose and how much money to give for their health.

Laryngeal pathologies are accompanied inflammatory process, soreness and discomfort. Medicine offers many drugs that effectively and quickly eliminate unpleasant symptoms. Positive reviews from doctors and patients lean towards a tool called Stopangin, the instructions for which are given below.

Stopangin is a local antiseptic for treatment infectious diseases throat and mouth. It is produced in two main forms - an aerosol (spray) for irrigation of the mucous membrane and a solution for mouth rinsing. The spray is actively used in ENT practice, and the liquid is used in dentistry. Although for the treatment of some diseases, both options are allowed.

The main action of Stopangin is aimed at disinfecting and anesthetizing mucous membranes and tissues. Has a proven anti-inflammatory and antifungal effect. After irrigation, it has an enveloping effect that softens and protects the throat. The main components quickly and effectively heal wounds and erosive formations.

Stopangin spray

The drug in aerosol form is used exclusively for local treatment of the larynx. Available in a 30 ml plastic bottle with a removable spray bottle included. Cardboard packaging, contains detailed instructions by application. In appearance, the liquid is transparent, a slightly cloudy shade is allowed, with a specific taste and smell.

The main component of the drug - hexetidine (concentration 0.2%) - has a strong bacteriostatic and antifungal action... The composition also contains essential oils of eucalyptus, anise, mint, orange tree, sassafras. A small amount contains menthol and methyl salicylate. Ethanol (96%), glycerin (85%) and sodium saccharinate act as auxiliary dissolving and coating agents.

Stopangin spray is most often prescribed by doctors to relieve painful symptoms in adults.

Stopangin solution

The Stopangin solution in the instructions for use is used mainly in dentistry to cleanse the oral cavity, sometimes for the treatment of throat infections. Produced in 100 ml glass bottles. Stopangin solution is completely ready for use, does not require dilution with water. Outwardly, it differs from the spray in color and smell. Has a slightly reddish tint and should be completely transparent.

The composition of the rinse preparation practically does not differ from the aerosol. The concentration of the active substance (hexetidine) is half as much and is 0.1%. Additionally added clove essential oil and dye. The smell of this form of Stopangin is very fragrant and pleasant, which distinguishes it favorably from the spray.

The Stopangin solution in the instructions for use is used mainly in dentistry to cleanse the oral cavity, sometimes for the treatment of throat infections.

Preparing a rinse with Stopangin takes exactly a couple of seconds, because even water is not needed. This advantage is of great importance.

Indications and contraindications

The list of indications for the use of Stopangin is very extensive, which allows us to call it a universal remedy for many diseases of the mouth and throat. It is actively used for the following pathologies:

• all forms of tonsillitis and chronic tonsillitis,
• pharyngitis,
• stomatitis,
• alveolitis,
• glossite,
• periodontal disease,
• candidiasis in the mouth
• during surgery and trauma,
• after tooth extraction,
• with tumor formations (to prevent superinfection).

Hexetidine has a powerful antibacterial effect, therefore it is used to prevent infection of the oral cavity and larynx in various medical situations. Even respiratory viral diseases can be treated with Stopangin, but only with an integrated approach.

The drug has no serious contraindications, except for hypersensitivity to the components. This is especially true with essential oilsthat may be allergens. Do not use Stopangin for children under 8 years old, with the exception of lotions with a solution when aphthous stomatitis... Stopangin is used with caution during pregnancy (contraindicated in the first trimester), but allowed during lactation.

Stopangin helps to cure many ENT pathologies, but precautions should not be neglected.

How to use Stopangin

Spray Stopangin instruction says that it is used twice a day, because the bactericidal and analgesic effect lasts up to 12 hours. It is advisable to irrigate the larynx after meals or in between meals. After that, it is recommended to refrain from food and water for some time.

The sequence of actions for treating a throat is as follows:

1. Remove the protective cap from the bottle.
2. Put on a removable spray.
3. Perform two test sprays into the air.
4. Hold your breath for a few seconds and irrigate the tonsils on both sides.
5. Rinse the nozzle under running water.

The medicine bottle must be held strictly vertically, inserting the nozzle into the mouth.

Children under 8 years old should not carry out such manipulations because of the risk of laryngospasm and the inability to hold their breath. In addition, the smell and taste of Stopangin often cause rejection in a small child. Up to 12 years of age the dosage can be halved - one spray on each side. Further allowed adult scheme treatment.

Stopangin solution for rinsing is not required to be diluted. You need to take 1 tablespoon of liquid and rinse your mouth with it for a long time (up to 30 seconds). The number of approaches should not exceed 5 times a day. The same recipe is suitable for lubricating the affected mucosa in children. Stopangin solution during pregnancy is also allowed.

The entire treatment course lasts on average 5 days, but no more than 7 at severe course disease.

Adverse reactions are recorded extremely rarely, usually associated with an individual reaction to the drug. For a short time, a burning sensation may occur, which quickly passes.

Stopangin is very easy to use and in most cases does not cause any discomfort.

Stopangin's analogs

The best analogue for Stopangin is Hexoral. It almost completely repeats the composition and has a therapeutic effect similar in effectiveness and power. But the cost is slightly lower. Moreover, the latter, according to numerous reviews, is best tolerated by children, while Stopangin is more suitable for adult patients. In any case, it is better to decide whether to choose Hexoral or Stopangin after consulting a doctor.

Stopangin 2A tablets and Stopangin 2A forte tablets are a good alternative or addition to therapy. In terms of composition, they are not entirely analogous and differ from the classical drug, but are not inferior in effectiveness. In addition, it is much more convenient and pleasant to dissolve tablets.

If it was not possible to purchase either Stopangin or Hexoral at the pharmacy, you can choose cheaper analogues - Stomatidin, Maxikold Lor, Anti-Angin. But the composition and pharmacokinetics of these drugs are slightly different.

Stopangin is good and effective remedy for the treatment of many diseases of the larynx. But its use must be agreed with the doctor.