Owner registration certificate:
LENS-PHARM LLC
S01AD (Antiviral drugs)
Before using POLUDAN you should consult your doctor. These instructions for use are for informational purposes only. For more complete information please refer to the manufacturer's annotation.
26.028 (Antiviral and immunomodulating drug for topical application in ophthalmology. Interferon synthesis inductor)
Lyophilisate for preparation eye drops white.
Excipients: sodium hydrogen phosphate (sodium phosphate 2-substituted), potassium dihydrogen phosphate (potassium phosphate 1-substituted anhydrous), sodium chloride.
Vials of 5 ml (1) complete with dropper caps (1) - cardboard packs. 5 ml bottles (3) complete with dropper caps (3) - cardboard packs.
Poludane is a biosynthetic polyribonucleotide complex of polyriboadenylic and polyriburidylic acids. Inductor of endogenous interferon synthesis. It has a pronounced antiviral and immunomodulatory activity.
The installation stimulates the production of endogenous interferon in blood serum and lacrimal fluid, which is determined 3 hours after administration.
A high level of interferon (111 U / ml in the blood and 75 U / ml in the lacrimal fluid) is maintained by daily injections throughout the course, on the second day after the cessation of administration, it is practically undetectable (the titer does not exceed 10 ND / ml). Strengthens the activity of natural killer cells, initially reduced in patients with ophthalmic herpes, as well as other immune cells.
Poludan solution, intended for installations in the eye, is prepared by dissolving the contents of the bottle in 2 ml. The ready-made solution can be used within 7 days if stored in the refrigerator.
Use in adults: 1-2 drops are instilled into the conjunctival sac 6-8 times / day. As the inflammation subsides, the number of instillations is reduced to 3-4 times / day.
Application in children: instilled into the conjunctival sac, 1-2 drops 3-4 times / day. As the inflammation subsides, the number of instillations is reduced to 1-2 times / day.
If there is no effect within 7 days, you should consult with your doctor about subconjunctival injections of the drug.
With the simultaneous use of Poludan with enzyme preparations due to the destructive effect of enzymes on endogenous interferon, the clinical efficacy of Poludan decreases.
Compatible with antibiotics and medicines for treatment viral infections.
Allergic reactions: itching, sensation foreign body, increased conjunctival injection, the emergence of individual follicles in the lower transitional fold.
In a dry, dark place at a temperature not exceeding 4 ° C. Keep out of the reach of children. Shelf life is 4 years. Do not use after the expiration date.
Poludan is prescribed for adults and children with viral eye diseases:
Side effects disappear on their own after discontinuation of the drug in 1-3 days.
In the pharmacy, you can buy several types of Poludan preparation: powder for making eye drops, lyophilisate for injections and powder for preparing nasal drops. For the treatment of eye infections, use eye drops from powder and lyophilisate for injection (it is dissolved and used for subconjunctival manipulations).
Poludan drops will have an antiviral effect with a number of infectious diseases eyes, scientists argue that the drug also has an immunomodulatory effect on the constituents of the eye, due to its structure.
The composition of Poludan, eye drops (lyophilisate for their manufacture) includes two active ingredients: polyadenylic (0.107 mg) and polyuridylic (100 mg) acids, as well as auxiliary substances: sodium and hydrogen phosphate chlorides, potassium dihydrogen phosphate. The drops also contain distilled water (powder for eye drops is diluted with boiled or distilled water).
The polyribonucleotide complex provides the induction of endogenous interferons and cytokines in the blood and lacrimal fluid, due to which the majority of herpetic, adenoviral infections are suppressed.
Eye drops Poludan after 25 minutes penetrate into all structures of the eye, into the blood and lacrimal fluid, provide the production of endogenous interferon, increase the activity of T-lymphocytes (they are responsible for the lysis of damaged eye cells).
As a result of this effect of the drug, a stabilization of the viral process is observed, and then regression and recovery occurs.
The use of these eye drops is associated with the "ability" of the active complex to activate the structures of the eye T-lymphocytes and cytokines, which affect the cells damaged by viruses, the production of their own interferon and their activation. The use of Poludan is indicated for diseases caused by many viral lesions, mainly herpes viruses and adenoviruses. So, Poludan is prescribed when:
These eye drops have very few contraindications: the instruction does not recommend using Poludan in the presence of allergic reactions to the main or auxiliary components of the drug.
Despite the fact that Poludan has been widely used, its effect on the intrauterine development of the fetus has not yet been studied, therefore ophthalmologists do not recommend prescribing this drug during pregnancy.
Since the constituent drugs penetrate the systemic circulation and breast milk, then it is not recommended to use it for HS. Other drugs are prescribed for nursing mothers and pregnant women for treatment.
Regarding the age of children from which Poludan drops can be prescribed, the instruction does not give precise instructions, but it is assumed that it is approved for use in pediatrics, and the doctor will determine the age for children.
The medicine is used in the complex treatment of viral infections. Often, ophthalmologists prescribe these eye drops, as well as subconjunctival injections simultaneously with antibiotics and other drugs for the treatment of viral and herpes infections of the eye.
However, Poludan, eye drops, the instruction does not recommend prescribing simultaneously with enzymatic drugs, since this reduces the effectiveness of the former.
It should be especially noted that during treatment with this drug it is not recommended to use alcoholic drinks, they may weaken the effect of the medicine or cause side effects.
Poludan is classified as a prescription drug by pharmacies. Ophthalmologists can prescribe the simultaneous use of drops and subconjunctival injections (carried out only in a hospital), but in some cases (uncomplicated course of the disease), only drops can be prescribed.
The standard appointment of Poludan, the instructions for use indicate as 6-8 instillations per day (after 4-6 hours), 1-2 drops in each eye. If only one eye is affected, drops are buried in the other to prevent the onset of the disease.
For children, the dosage is 1 drop and 3-4 instillations per day (after 6-8 hours).
Drops are instilled strictly into the conjunctival sac (on the mucous membrane of the lower eyelid between the back wall of the eyelid and the anterior part of the cornea), contact with the conjunctiva can cause severe burning.
Before the start of the procedure, remove contact lenses and put them in place 20 minutes after the manipulation.
Usually, at the beginning of treatment, instillation and injections are more frequent, and as they recover, their number decreases (up to 3 per day).
The duration of treatment with Poludan eye drops is from 7 to 10 days. When prescribing injections, the treatment ranges from 7 to 15 procedures with the simultaneous instillation of drops between them. As a rule, injections are prescribed when the instillation efficiency is low.
A feature of this drug is that it is not possible to find the eye drops themselves in pharmacies; only powder (lyophilisate) is sold. The lyophilisate must then be diluted in distilled water and is used for subconjunctival injections. The powder, packed in plastic bottles with dropper caps, is dissolved in a clean boiled water room temperature(or water for injection) and used for instillation into the conjunctival sac.
The order of dilution and dosage is indicated in the instructions for the preparation. Usually, for eye drops, 0.2 mg of powder is diluted in 2 ml of water.
Side effects are rare. During the use of Poludan, the following undesirable symptoms were recorded when eyes were buried:
If undesirable manifestations occur, the drug is canceled. The symptoms that have arisen do not require treatment, they disappear on their own within 1-3 days.
Overdose cases have not been described.
The hermetically sealed product can be stored for 4 years from the date of issue. After opening the bottle of Poludan, the eye drops are stored in the refrigerator at a temperature not exceeding + 4 and not longer than 7 days.
Among analogues, this drug has a budgetary price.
Analogs of this medicine are called:
The price of powder (lyophilisate) for Poludan eye drops in pharmacies in Moscow ranges from 135 to 555 rubles, for 15 ml of solution, on average - 247 rubles. The package contains 3 plastic bottles with dropper caps.
There are no foreign analogues of this drug, it was created by domestic scientists, and is produced by the pharmaceutical concern LENS-PHARM, Russia.
Today, cases of the development of eye diseases have become more frequent. For their treatment, effective eye drops are prescribed. But only their use is allowed after an accurate diagnosis. Poludan drops remain one of the most effective and popular.
This is a unique drug that effectively copes with viral inflammation. The medicine can be used by both adults and children, but only after being prescribed by the attending physician.
Poludan is an antiviral drug based on a polyribonucleotide complex. It serves for the treatment of herpes and adenovirus infections that have affected the organ of vision.
The therapeutic effect of the drug is based on the induction of the synthesis of endogenous interferons and cytokines in the blood and interferon in the lacrimal fluid.
One bottle of medicinal solution contains:
Additional components of the medication include:
Poludane refers to a complex of polyribonucleotides that have been obtained by biosynthesis. The medication has immunomodulatory and antiviral effects.
You may also find it useful to know more about how you can cure and with which drops.
After instillation, the solution quickly penetrates the tissues of the organ of vision, is determined in blood serum and lacrimal fluid. Active ingredients very quickly excreted from the body.
Poludan drops are prescribed for the treatment of the following pathologies:
The maximum effectiveness of the drug is observed in relation to adenoviruses and herpes viruses.
You may also be interested in learning about what it looks like and how it is treated.
On the video - how to bury your eyes:
The positive effect of the use of drops is achieved only if the dosage and duration of treatment are correctly observed.
Drops are prescribed for the treatment of various superficial viral pathologies of the organ of vision. After preparing the solution, it is necessary to send it to the affected eye in an amount of 1-2 drops. If there is acute inflammation, then drip the drug 6-8 times a day. But what the inflammation of the lacrimal sac looks like, and how the treatment of such a disease occurs, indicated
As you recover, the number of instillations should be reduced to 3-4 times a day. The duration of the therapeutic course is 7-10 days. It is determined by the attending physician, taking into account the type of pathology and its course. It is not worth using drops longer than the specified period, since there is a risk of addiction.
If there is no effect of therapy, then the doctor decides on the subconjunctival administration of the medication. In the treatment of stromal keratitis, choreoretinitis, viral uveitis and optic neuritis caused by a viral lesion, drug injections are used under the conjunctiva.
To prepare a medicinal solution, you need to take 1 ml of water and send the contents of the bottle. Inject a solution of 100 mcg subconjunctivally 1-2 times a day. The course of therapy will be 15-20 injections. But what the subconjunctival hemorrhage of the eye looks like, you can see
Poludan drops are firmly entrenched in pediatrics in the treatment of various viral diseases of the organs of vision. Inject the solution under the conjunctiva in the amount of 1 drop 2-3 times a day. Treatment should not exceed 7-10 days. With the development of such unpleasant symptoms as burning, stinging, pain, parents should consult a doctor. but why it may appear, you can find out from this article.
You can buy Poludan eye drops at any pharmacy without a doctor's prescription. The average price of a package (10 ampoules of 1 ml) is 500 rubles. You can use and
If, for some reason, it is not possible to purchase Poludan drops or side effects occur when using them, then there is an alternative option - buying an analogue. These are drugs that are similar in purpose. The following analogs remain effective and the most popular:
We continue to analyze effective medications that help get rid of certain eye problems.
In this article, we'll take a look at Poludan.
It is an antiviral drug based on a polyribonucleotide complex intended for the treatment of herpes and adenovirus eye infections.
The principle of action of this drug is associated with the induction of the synthesis of endogenous interferons and cytokines in the blood and interferon in the lacrimal fluid.
One bottle for the preparation of drops contains a complex of polyuridylic and polyadenylic acids, potassium salt of polyriboadenylic acid, potassium salt of polyriboadenylic acid.
Excipients are potassium dihydrogen phosphate, sodium hydrogen phosphate, sodium chloride.
Poludane is a complex of polyribonucleotides obtained by biosynthesis. The drug has immunomodulatory and antiviral effects.
The mechanism of action is associated with the stimulation of the formation of immune defense factors in the body - endogenous interferons and cytokines, an increase in the activity of T-killers, which are responsible for the production of interferon gamma and the recognition of foreign antigens.
After instillation, the solution penetrates well into the tissues of the eye, is determined in blood serum and lacrimal fluid, and is quickly eliminated from the body.
This drug can be used concurrently with other medicines to treat viral infections and antibacterial agents.
The drug is prescribed for the treatment of viral eye lesions (primarily herpetic and adenoviral):
The drug is prescribed as subconjunctival injections or eye drops.
In the form of instillation, the drug is prescribed for the treatment of superficial viral lesions of the eyes, such as conjunctivitis, keratitis, keratoconjunctivitis.
After preparing the solution, it is instilled into the affected eye in 1-2 drops, with acute symptoms it is required to bury the eye 6-8 times a day, as the patient recovers, the dose is reduced to 3-4 times a day.
The duration of the course of treatment should be determined by the attending physician, as a rule, it ranges from 7 to 10 days.
If there is no effect of treatment, subconjunctival administration of the drug is prescribed.
For the treatment of stromal keratitis, choreoretinitis, viral uveitis and optic neuritis caused by a virus, it is necessary to inject the drug under the conjunctiva.
To prepare the solution, the contents of the bottle must be dissolved in 1 ml of water for injection or novocaine. The solution is injected subconjunctivally 100 μg once a day or every two days.
The course of treatment requires 15-20 injections. For the treatment of viral eye lesions in pediatric patients, a half dose is administered under the conjunctiva, the course of treatment requires 8 to 10 injections of the drug.
The drug should not be used if there is an individual intolerance to any component.
At this time, there is no data on the use of Poludan during pregnancy or lactation, but most doctors say that the drug is not able to have a negative effect on the fetus.
Among side effects observed when using the drug in the form of eye drops, the most common are eye irritation and local allergic reactions in the form of burning, itching, congestion of the vessels of the sclera.
In cases of administration of the drug in the form of an injection, it is possible to increase the vascular pattern of the mucous membrane of the eye or edema of the eyelid. In some cases, the introduction of the solution into the anterior chamber of the eye is accompanied by a short-term increase in intraocular pressure, as a result of which small hemorrhages appear.
These phenomena are reversible and in most cases go away on their own in 1-3 days after the end of the use of the drug.
There is no data on cases of overdose with this drug.
It is not advisable to combine any antiviral drugs with the use of alcohol. Alcohol can weaken medicinal effect from the drug, pervert it or intensify the manifestation side effects.
The following medicines are similar in purpose:
The average cost of Poludan eye drops in Russian pharmacies is 170 rubles.
On the Ukrainian market, this drug costs on average 150 hryvnia.
Among the reviews about this drug there are both positive and negative. Many patients use it to treat viral eye diseases such as conjunctivitis, keratitis and others. Since diseases are viral, the infection is quickly transferred from one eye to another and the person begins to experience many unpleasant sensations.
Positive reviews. The use of drops for many who have used it stops all unpleasant symptoms such as burning, itching, severe redness, swelling, pain, tearing and pus stop. Some people note that the medicine has a quick effect on the first day of use.
Others, observed a positive effect from the drug not immediately, but after a few days, a week. Poludan is successfully used to treat eye infections in childhood... In general, positive reviews guarantee the effectiveness of the drug and a guaranteed result.
Negative reviews. There are also negative reviews about the drops. Patients complain about the short shelf life of the finished medicine and inconvenient packaging, that the medicinal solution is not sold ready-made, but must be prepared by themselves, buying water for injection in addition to the powder.
The drops did not help many who were treated for the simple reason that initially the doctors did not accurately establish the nature of the origin of conjunctivitis. It is worth noting that drops help only with a viral disease, they do not cure a bacterial disease.
№1. They put me in the hospital, since I hadn't seen a doctor for a long time. At first, there was a slight pain in the eyes - I decided it was because of the TV. A few days later, discharge went from the eyes, I washed my eyes with various herbal infusions. Even later, rashes and itching appeared on the skin. Only then did I go to the clinic, where it turned out that it was a herpes infection.
The doctor gave me a referral to the hospital, where I underwent a course of treatment with Poludan, who injected my conjunctiva. I was very afraid of injections, but the fears were completely in vain, since there was no pain at all, but I immediately felt relief. I am very glad that the drug helped, as the doctor said that my poor eyesight could have deteriorated greatly.
№2. Several months ago, I picked up viral conjunctivitis- the redness did not go away, the eye was inflamed, even the tetracycline ointment did not help. After using the Poludan drops, the result was not long in coming - the edema of the eye decreased significantly, the redness disappeared, as did the itching.
You need to use drops for a long time, at least 2 weeks, but believe me, the effect is worth it. Another advantage of the drug is that it is immunostimulating, therefore, there is no need to take antibiotics.
After instillation, the sensation of a film on the eyes does not appear, that is, the drug does not affect visual acuity in any way. Of course, allergic reactions are also possible, but I have not experienced any. Take care of yourself and be healthy!
Poludan is an ophthalmic drug that has antiviral and immunomodulatory effects. Part medicinal solution includes a polyribonucleotide complex, which is intended for the treatment of eye infections with a herpetic and adenoviral nature.
Drops interact well with various drugs, so it can be safely used in the complex treatment of diseases. However, it should be carefully used simultaneously with enzyme preparations that can reduce the therapeutic and beneficial effect of Poludan.
The disadvantage of using the drug is that it must be prepared independently from powder and water for injection. Moreover, the method of application is similar to any other drops that are instilled into the conjunctival sac with clean hands. The dosage and course of treatment are established by the doctor or the one that is attached to the instructions for the drug is observed. There are practically no contraindications to the drug, but there are many side effects, including eye irritation, swelling, etc.
Among effective and strong drugs, which relieve problems with the organs of vision, allocate Poludan.
The drug is based on a polyribonucleotide complex. It treats herpetic as well adenovirus infections... Copes well with various diseases who wear acute form and are difficult to treat.
Poludan eye drops are classified as unique medical drugs specially designed to eliminate adenovirus infections.
It differs in a simple principle of action, and also interacts with the induction of division of endogenous interferons, as well as cytokines in the blood.
Poludan has an antiviral and immunomodular effect. Penetration into the tissue of the organ of vision occurs after the use of the drug.
It enters the lacrimal fluid, and then is determined in the blood serum. It does not stay in the body for a long time.
One bottle of Poludan contains two types of acid: polyadenylic acid and polyuridylonic acid.
In addition, the medication consists of a number of elements:
The medicine Poludan is released in glass jars, covered with a dropper lid on top. The drops have a volume of 5 ml.
In the pharmacy, the drug is sold in the form of a lipophysate.
For the preparation of eye drops, use purified water intended for injections.
An auxiliary substance in the manufacture of the product is potassium hydrogen phosphate, along with sodium hydrogen phosphate, as well as sodium chloride.
In addition to the drug, the package contains three additional bottles.
With the help of the medicine Poludan, viral lesions of the visual organ are treated:
After using Poludan, the listed problems disappear.
The content of Poludan is dissolved in 2 ml of water, and then the medicine is used for installations in the organ of vision. Use the ready-made solution for no more than 7 days; during storage, observe the drug and keep it in the refrigerator.
Drug dosage:
In some cases, there is no effectiveness after using the drug, if this is observed within 7 days, you need to consult a doctor and determine why there is no effectiveness.
According to the instructions medicine Poludan is intended for use in the form of eye drops, as well as subconjunctival injections.
Poludan has one goal and purpose - he copes with superficial viral damage to the organ of vision. The doctor prescribes the medicine Poludan against conjunctivitis, as well as keratitis and keraconjunctivitis.
As drops:
In the form of injections:
During the gestation of a child, as well as breastfeeding, no special indications were found. According to the majority of doctors, Poludan does not negatively affect the development of an intrauterine child.
Pregnant women can use the drug only after the permission of a specialist. He should pay attention to the positive and negative aspects, given the condition of the expectant mother.
In children's practice, experts allow the use of the drug Poludan and with the help of it heal viral diseases organs of vision.
Currently, no specific contraindications have been found. If an individual intolerance to certain ingredients of the drug is identified, it is not used.
Such cases are rarely found, sometimes the Poludan remedy is not prescribed when an infection of the teeth is detected, as well as a disease of the paranasal sinuses.
There are the following:
The occurrence of the listed phenomena does not pose a danger, they are reversible and do not require special treatment. After a while, the symptoms disappear, it takes 1-3 days.
After taking the drug Poludan, there are no deviations in excess of the prescribed norm.
When viral disease before using Poludan, in spite of the form in which it should be taken, a specialist consultation is necessary.
Poludan means belongs to complex treatment, with which the patient is treated.
At any dosage form it is allowed to combine the drug with other antibacterial drugs, as well as with antibiotics and medicines that belong to the general complex treatment established by a specialist.
The therapeutic effect of the drug will be reduced by the combination with enzyme preparations, so this must be taken into account and not combined.
Drops go well with a number medicines designed to get rid of bacterial as well as viral infections.
Poludan drops belong to the group of polyribonucleotins, they were obtained using biosynthesis.
According to some experts, the drug has an immunomodulatory and antiviral effect. It has a simple mechanism of action, it will stimulate the emergence of immune defense factors. After penetration into the body, endogenous interferons will appear, an increase in the activity of T-killers is observed, they recognize foreign antigens.
In addition to Poludan, there are analogs that are similar in purpose:
On average, Poludan eye drops are sold in pharmacy kiosks for 170 rubles... In the Ukrainian markets, you can buy the drug for 150 hryvnia.
Poludan eye drops must be stored in a designated place not exceeding 4 degrees.
The room must be dry and free from sunlight.
Babies are forbidden to play and hold the medicine in their hands, so choose a remote place for storage.
After the expiration date, you can not use drops and enter into the membranes of the organs of vision.
The drug Poludan is sold in pharmacy kiosks after providing a doctor's prescription. He is not released without the permission of a specialist; it is imperative to show the employee of the pharmaceutical point an extract from the attending doctor.
The drug Poludan differs from the others in that its side effects do not require and do not need treatment. After a while, they go away on their own, sometimes it only takes 1-3 days.