Eye drops Halfd - drug TreatmentWith pronounced antiviral and immunostimulating effect.

Structure

The acting principle is a synthetic polynucleotide complex of active acids: poliribadenylova and polirobaridilova 100 units.

As auxiliary substances in the composition are:

• sodium chloride in an amount of 8.5 mg;
• sodium hydrophosphate in the amount of 2.0 mg;
• potassium hydraulic phosphate in the amount of 0.408 mg.

The drug is an inducer of the synthesis of endogenous interferon and other cytokines in lymphoid structures.

Under its influence, for several hours, the concentration in the blood and the tear liquid of alpha interferon is significantly increased, to a lesser degree of beta interferon and gamma interferon.

Confirmed clinically activity, the effectiveness of the means against Influenza viruses, herpes, respiratory viruses.

Price in Pharmacies

The cost of one packaging of the drug depends on the number of bottles in the box, destination.

The price may vary in different regions, be cheaper in Internet pharmacies, with wholesale purchases.

Indications for use

The drug can be applied in ophthalmological practice in adults and children. Indication to use is the presence of viral or combined damage to the structures of the eye.

The means in the form of droplets into the eyes or subconjunctive, parabulbar, retrobulbar injections is prescribed under the following pathologies:

• keratoweeite;
• viral etiology.

Contraindication to use is the intolerance to the basic active components of the drug or auxiliary substances present.

Instructions for use

The middle of the eye disease is prescribed locally in shape. eye drops or in the form injections.

The technique is selected individually to the ophthalmologist, depending on the localization of the lesion, the degree of distribution and launching of the process, the presence of complications.

Drops

The pharmacy preparation is a dry lyophilisate in the form of a white powder for the preparation of therapeutic solution.

To prepare eye drops, the contents of the bottle are divorced by two milliliters of distilled water. Used by appointment after complete dissolution of powder.

The shelf life of the prepared solution is 7 days Subject to storage in temperature conditions not higher than +4 degrees.

• The process of instillation medication in the eyes is preceded by a thorough wash of hands. The bottle is slightly warmed in the hands of avoiding unpleasant sensations.
• The procedure is carried out in the position of the patient sitting or lying with a slightly trapped head.
• Eyes are pre-cleaned disinfectantsIf there is a pathological separated.
• The mild movement is open to the conjunctival fold behind the lower eyelids, they ask to reverse up and bring 1 - 2 drops into the conjunctival bag.
• After instillation, for a few minutes, it is necessary to close the eyes and press the area of \u200b\u200bthe nose-peer channel with a sterile napkin, so that the medicine has processed the conjunctival outside and penetrated into the tissue.

Adultthe number of orders per day 6 - 8 is assigned, as inflammation is elected to 4. The duration of the course of treatment is determined by the doctor individually.

Feature use eye drops in childrenis to reduce the number of instillations to 3 - 4 per day. According to the testimony, the dose may increase.

Viral infections are highly contagious. Careful washing hands Before the procedure, after it is fulfilled.

Shows

In the absence of positive dynamics during a week or initially heavy viral lesions of the eye structures, the drug injection route is used: subconjunctive, parabulbar, retrobulber.

It is possible to introduce the drug into the front chamber of the eye.

• To carry out subconnalistic procedures, the contents of the vial are mixed with 1 ml of water for injection or 0.5% novocaine solution.
• The drug is introduced under the conjunctival of 0.5 ml every other day or daily.
• A total of 15 to 20 injections is assigned to the course of treatment.

The technique is used in keratoiridocyclitis, stromal.

Childrenone procedure is enough 0.25 ml of solution. The duration of the course is determined individually. When conducting treatment, it is necessary to comply with hygienic rules.

With viral lesions of deep structures or rear departments Injections are performed peripulously: parabulbarno or retrobulbarno. The lyophilisate of the drug is dissolved in 1 ml of 0.5% of novocaine. One procedure uses 1 ml of solution. The course of treatment includes 10 - 20 injections held every other day. The technique is shown in viral neuritis spectator nerve, uveitis, chorioretinites.

With heavy forms of herpes keratoiridocyclitis It is possible to introduce a semi-grandpa to the front chamber of the eye. The procedure is carried out in operating conditions. The contents of the bottle of the drug are bred in 1 ml of water for injections, by means of a tuberculin syringe introduced into the front chamber in an amount of 0.3 - 0.5 ml. The procedures are carried out with a frequency of 2 - 3 per week, the course is calculated 3 - 5 of the introductions.

Sometimes in parallel with the defeat viral infection The eye suffers and face skin.

For quick relief of skin manifestations Applied subcutaneous administration of the drug in the course of herpetic rashes. To carry out injections, the contents of 2 seamida vials are dissolved in 10 to 20 ml of 0.5% of novocaine. Pricks make daily within 3 - 6 days. At the same time decrease painfulness, rash elements undergo reverse development.

Interaction

Injection solutions are prepared immediately before administration, they are not subject to storage.

Application of drug compatible Using others antiviral tools, antibiotics with combined tissue damage. Instillations of drugs are preferably not at the same time, but with an interval of 20 - 30 minutes.

It is undesirable to prescribe a drug in parallel with enzymes due to the destruction of interferonov, the antiviral effect will decrease.

Side effects

When using a semi-grandma, the appearance appearing in the form of itching, enhanced hyperemia sclera, edema eyeball and eyelids.

With an injection path of administration, temporary, hemorrhage is possible.

Pathological manifestations disappear when canceling the drug.

The halfdan is sold in pharmacies without a recipe, but to start it use, it is recommended to consult an ophthalmologist.

Among the effective and strong drugs that are eliminated from problems with the organs of vision, it is distinguished by a semi.

The medication is based on a polyribonucleotide complex. He treats herpety, as well as adenovirus infections. S. perfectly copes various diseasesthat wear acute form And heavily treatable.

Eye Solution

Eye drops are selected to unique medical medicines specifically designed to eliminate adenoviral infections.

It is distinguished by a simple principle of action, and also interacts with the induction of the division of endogenous interferons, as well as cytokines in the blood.

Act

The semi-grandfather is expressed by antiviral, as well as immunomodular action. Penetration in the tissue of the organ of vision occurs after the use of the drug.

It enters the tears, and then it is determined in serum. In the body is not delayed for a long time.

Structure

In one bottle, the halfdan is two varieties of acid: polyadenyl and polyuridylon.

In addition, the medication consists of a number of elements:

• potassium salt polyyroadenyl acid;
• digidrofosphot potassium;
• the composition includes sodium hydrophosphate;
• sodium chloride.

Form release

The medicine is reserved in glass jars, covered with a dropper cover from above. Drops have 5 ml.

In the pharmacy, the drug is sold in the form of a lipophizat.

For the preparation of eye drops, purified water intended for injections is used.

The auxiliary substance in the manufacture of the means is potassium hydraulic phosphate, together with it sodium hydraulic phosphate, as well as sodium chloride.

In addition to the drug in the package there are three additional bottles.

Indications for use

With the help of a medical agent, the viral lesions of the visual organ is treated:

• the appearance of choreoretinites;
• the presence of conjunctivitis;
• the emergence of keratitis;
• uveitis;
• if deep keratitis appeared;
• as well as iridocyclites.

After using the selected, the listed problems disappear.

Instructions for use

Dosage

In 2 ml of water dissolve the contents of the semi-grandpa, and then the medicine is used to install into an organ of view. With a finished solution to use no more than 7 days, while storing to observe the drug and keep it in the refrigerator.

Dosage of the drug:

In some cases, there is no effectiveness after applying the drug, if it is observed within 7 days, it is necessary to refer to the doctor and determine why there is no efficiency.

Mode of application

According to the instructions, the medical device is intended for use in the form of eye drops, as well as subconjunctive injections.

The purpose and purpose of the semi-grandpa is one - it copes with the superficial viral lesion of the organ of vision. The doctor prescribes a medicine forces against conjunctivitis, as well as keratitis and keraconjunctivitis.

Drops

In the form of droplets:

Shows

In the form of injections:

Use during pregnancy and children

During the rigging of the child, as well as breastfeeding, not detected special readings. In the opinion of most of the doctors, the halfda does not affect the development of an intrauterine child.

Pregnant women can use the drug only after permission from a specialist. He must pay attention to the positive and negative sides, given the state of the future mother.

In children's practice, experts are allowed to apply the medicine of the halfdan and with the help of it to treat viral diseases of the organs of vision.

Contraindications

Currently, special contraindications are not found. If individual intolerance to individual drug ingredients is revealed, it is not used.

There are rarely cases, sometimes the agent is not prescribed to the dental infection, as well as illness putty sinuses.

Side effects

There are following:

The appearance of listed phenomena does not pose a danger, they are reversible and do not need special processing. After some time, the symptoms disappear, it leaves from 1-3 days.

Overdose

After using the drug, the halfda is not observed by deviations.

Interaction with other drugs

When viral disease Before applying the semi, despite the fact that it must be taken, a specialist consultation is necessary.

The remedy for integrated treatmentWith which the patient is treated.

At any dosage form It is allowed to combine the drug with other antibacterial drugs, as well as antibiotics and medicines, which relate to a common comprehensive treatment established by a specialist.

Therapeutic effect drug will reduce the combination of S. enzyme preparations, so it must be considered and not combined.

The drops are well combined with a number of medicines intended to get rid of bacterial, as well as viral infections.

Beneficial features

The drops of the semi-lines belong to the polyribonucleotin group, they were obtained using biosynthesis.

According to some specialists, the drug has an immunomodulatory and antiviral action. He has a simple mechanism of action, it will stimulate the emergence of immune protection factors. After penetration into the body, endogenous interferons will appear, an increase in the activity of T-killers is observed, they recognize alien antigens.

Analogs

In addition to the semi-grandpa, there are means of analogues that are similar to purpose:

• OKUFERON - He has a different composition, but a similar antiviral effect. average price 490 rubles.
• Ophthalmferon - It has a different composition, but it looks like a similar antiviral action. TO positive feature The absence of a negative impact on the patient's body. Price 300 rub.
• Aktipol. - consists of an important substance - an aminobesumic acid, he also, as in the semi-pidnam, is expressed antiviral, as well as an immunomodulatory effect. Cost 150 rub.

Price

On average, the eye drops are sold in pharmaceutical kiosks for 170 rubles. In the Ukrainian markets it is possible to buy the drug for 150 hryvnia.

Storage conditions and shelf life

The eye drops of the semi must store in a reserved place not exceeding 4 degrees.

The room should be dry and without penetration of sunlight.

The kids are forbidden to play and keep the medicine in your hands, so it is for storing to choose a distant place.

After the expiration date, it is impossible to use drops and introduce into the shell of organs of vision.

Terms of sale

The preparation is selected in pharmaceutical kiosks after providing a doctor's prescription. He is not allowed without permission from a specialist, it is necessary to show an employee of the pharmaceutical point of an extract from the attending doctor.

special instructions

The preparation is different from the rest of him sideflines Do not require and do not need treatment. After some time, they pass on their own, sometimes it takes only 1-3 days.

The lyophilisate for the preparation of eye drops is 1 FL. polyiribadenyl acid potassium salt (potassium polyyroadenylate) - 0.1 mg of polyyrotic acid acid potassium salt (potassium polyrioticuridelate) - 0.107 mg Auxiliary substances: sodium hydrophosphate (sodium phosphorous acidized) - 2 mg; potassium dihydrophosphate (potassium phosphorosphospheres single-dismeditable) - 0.408 mg; sodium chloride - 8.5 mg in 5 ml bottles of 100 units, in a set with 1 or 3 sterile lid-droppers; In a box of cardboard 1 or 3 sets.

Indications for use

Viral eye diseases: Powder for the preparation of eye drops: adenovirus and herpetic conjunctivitis; Surface keratoconjunctivitis; keratitis. Powder for the preparation of subconjunctive solution: keratoiridocyclite (keratoowet); adenovirus and herpes conjunctivitis; keratitis, stromal keratitis; Iridicyclitis; chorioretinite; neuritis of the optic nerve (viral etiology).

Contraindications for use

Hypersensitivity. For the introduction into the front chamber of the eye: keratoiridocyclites with an ulceration of the front surface of the cornea; Conjunctivitis, in the presence of pathogenic microflora in the sowing with conjunctiva; infection of teeth and the apparent sinuses of the nose.

Separate application for pregnancy and children

Perhaps during pregnancy and lactation period, as appointing a doctor.

Side action

Eye drops: allergic reactions (itching, feeling of the foreign body, enhancing the conjunctival injection, the occurrence of individual follicles in the lower transitional fold). Subconjunctive Introduction: Swelling of the lower eyelid, enhancing the conjunctival injection. Insertion into the front chamber of the eye: short-term rise intraocular pressure, the appearance of hemorrhages in the front chamber, enhancing the thyndalization of the moisture of the anterior chamber. The factors disappear independently after the discharge of the drug for 1-3 days.

Dosage halfdan

Apply in adults in the form of eye drops and injections under conjunctiva. In the treatment of adenoviral and herpes conjunctivitis, surface keratoconjunctivitis and keratitis, the semi-finished solution is buried in a conjunctival bag of a patient's patient 1-2 drops 6-8 times / day. inflammatory process The number of instillations are reduced to 3-4 times / day. In the treatment of adenovirus and herpetic conjunctivitis, stromal keratitis and keratoviridocyclites (keratuettes), iridocyclites, chorioretinites, neurites of the optic nerve The drug is used in the form of subconjunctive injections. Enter 0.5 ml (100 μg) under the conjunctival of the eye daily or through a day. Current treatment 15-20 injections. The rules of preparation of solutions: a semi-finished solution is prepared by dissolving the contents of the vial (200 μg) in 2 ml of distilled water. For the preparation of the solution for subconjunctive injections, the contents of the vial (200 μg) are dissolved in 1 ml of sterile water for injections.

The halfdan is pharmacological preparationrelating to inducers of interferon synthesis and manifest expressed antiviral and immunostimulating activity.

Release form and composition

The main ingredient of the semi-grandfather is represented by a polyadenyl and polyuridyl acid complex contained in 5 ml of 100 unit preparation (200 μg). Additional components are included in the form: sodium chloride, dihydrophosphate potassium, sodium hydrophosphate. It is made in the form of a lyophilisate designed for further preparation:

• Eye drops - in a volume of 5 ml in glass vials complete with a sterile lid of a dropper embedded by 1 or 3 into secondary packaging;
• Solution for subconjunctive injections (administrations under the conjunctival) - in ampoules of 1 ml, located 10 pieces along with a scarifier in a pack of paper;
• Drops of nasal - in 5 ml bottles, packed 1 or 3 pieces together with lids droppers in cardboard boxes.

Ready drops of nasal in volume 5 ml of 50 units per 1 ml are also available, in flocks-droppers.

Indications for use

According to the instructions for the semi-finance, the use of the drug in the form of injection solution And the eye drops are recommended for viral eye lesions in adults and children. The drug is used on the background:

• Keratitis and keratoviridocyclites (keratowets);
• Adenovirus and herpetic conjunctivitis;
• Chorioretinites;
• Stromal keratitis;
• Iridocyclitis;
• Neurovers of the optic nerve.

Nasal drops are prescribed with ARVI therapy, including influenza.

Contraindications

• Lesions of the apparent sinus and teeth, infectious nature;
• Conjunctivitis with the detection of pathogenic flora in bacteriological sowing with conjunctiva;
• Ulcerative defects of the cornea (front wall).

Methods of application and dosage

The nasal drops of the halfdan, according to the instructions, are used locally, introducing adults to each nostril 2 drops of a solution 5 times a day for 5 days - starting to use the drug no later than two days from the moment of observing the first signs of viral lesion. For the preparation of the solution, the lyophilisate stored in the bottle is bred by purified water to a label applied to the label.

The use of the semi-shaped semi-shaped semiconductor is recommended by adults in the dosage of one or two drops introduced into internal corner Eyes 6-8 times a day, children recommend one-time dose 1-2 drops, in 3-4 reception. With a decrease in signs of inflammation, the multiplicity of administration is reduced: in adults up to 3-4, in children up to 2-3 times. To obtain instillation solution, the contents of the vial are required in a dose of 200 μg to dissolve in 2 ml of distilled water. If for a week not noted therapeutic effect From receiving drops, injections can be appointed.

To prepare a solution for injections for conjunctiva, the lyophilisate in a dose of 200 μg is divorced in 1 ml of water for injection. Adults are prescribed by the introduction of a semi-day 0.5 ml every other day or daily, the course may consist of 15-20 injections. Children prescribe a dosage of 0.25 ml every other day, the duration of therapy 8-10 injections. The solution is required to be administered in the stationary.

In the treatment of uveitis, chorioretinites, neurites of the optic nerve (herpetic lesions of the rear sections of the eye) The contents of the semi-granddama can also be diluted with a solution of novocaine 5%, in a volume of 1 ml. Adult injections in 1 ml dosage are carried out in a day, the drug is introduced under the hospital conditions by a parabulbar method (through the lower eyelid to the depth of one cm), the course is 10-20 injections.

Side effects

When using a semi-grandmother in rare cases may appear allergic reactions. Injection can sometimes be accompanied by an edema of the lower eyelid, an increase in intraocular pressure, small hemorrhage. Side effects Usually disappear a few days after the cessation of treatment.

special instructions

The use of semi-finance is often combined using drugs intended for therapy of viral lesions.

Enzymes reduce the effect of the drug.

Analogs

The analogues of the semi-finance for the mechanism of action include:

• Eye ointment - Zovirax, Bonafon, Acyclovir, Ophthalmferon, Virolex, Helepin-D;
• Tablets - Anaferon, Galavit, Arpeflu, Immunal, Arpetolide, Vobenzyim, Imudon, Methyluracil, Neuroferon, Cycloferon, Immunorm, Polyoxide, Ribominyl, Timakdid, Echinacea;
• Lyophilisate - cycloferon, Timalin, Steamfort, Reksod, Impon-Vac, Colorsin, Immunomax, Hepon, Vilozen, Bestim, Affinlavykin.

Terms and conditions of storage

The semi-form of lyophilisate needs to be kept, by annotation, in a place with a temperature not exceeding 4 ° C, dumps are nasal - up to 25 ° C. The shelf life of the lyophilisate - 4 years, nasal drops - 2 years.

Instructions for use. Contraindications and form of release.

Instruction
for the use of drug
Halfd

ATX
S01AD antiviral drugs

Composition and form of release
Lyophilisate for cooking nasal drops 1 FL.
polyriaadenyl acid Kaliya salt (potassium polyyroadenylate) 0.1 mg
polyrybauridyl acid Kaliya salt (potassium polyrioticuridelate) 0.107 mg
auxiliary substances: sodium hydrophosphate (sodium phosphate dubbed) - 2.0 mg; potassium dihydrophosphate (potassium phosphorosphospheres single-dismeditable) - 0.408 mg; Sodium chloride - 8.5 mg
in 5 ml bottles of 100 units, in a set with 1 or 3 sterile lid-droppers; In a box of cardboard 1 or 3 sets.

pharmachologic effect
Pharmacological action - immunostimulating.

Pharmacodynamics
The semi-bosynthetic polyribonucleotide complex polyiribadenyl and polyariboreuridyl acid. Inductor synthesis of endogenous interferon and other cytokines. Stimulates education, mainly alpha interferon, to a lesser degree - beta and gamma interferon. Induces interferon synthesis in peripheral blood leukocytes, as well as in tissues and organs containing lymphoid elements. High level Interferon is supported by daily administration throughout the course. It has a direct anti-virus action against influenza viruses and other ARVI. Moderates cytokine response when infected with virus cells.

Preparations of Preparation Polidan®
Treatment of ARVI, incl. flu.

Contraindications
Increased sensitivity to the components of the drug.

Side effects
Allergic reactions are rare.

Interaction
With the simultaneous use of semi-grandfather with enzyme preparations, its clinical efficacy decreases due to the destructive effect of enzymes on endogenous interferon. Compatible with antibiotics and drugs for the treatment of viral infections.

Method of application and dose
Locally.
The drug is used in adults to treat flu and other ARVI in the form of droplets into the nose. I bury 2 drops to each nostril 5 times a day for 5 days in a sharp period of the disease - no later than 24-48 hours from the moment the first symptoms appear.
The semi-finished solution is prepared by dissolving the contents of the bottle (100 units) boiled water up to the label specified on the label.

special instructions
Side effects are transitious and disappeared after canceling the preparation after 1-3 days.

Conditions for the storage of the drug Polidan®
In the place protected from light, at a temperature not higher than 8 ° C.
Keep out of the reach of children.

The shelf life of the drug Polidan®
4 years.
Do not apply after the expiration date indicated on the package.