General characteristics:
international UnPatented Name: Dimethylsulfoxidum;
basic physico-chemical properties: Colorless liquid or colorless crystals. Gigroscopic.

structure:
active substance : dimethyl sulfoxide is not less than 99%.

Release form. Liquid for outdoor use.

Pharmacotherapeutic group.
Funds used locally with articular and muscle pain. PBX code: M02A x03.

Pharmacological properties.
Pharmacodynamics. Dimethyl sulfoxide penetrates well through biological membranes, including through the skin and exhibits transport properties, contributing to penetration through the skin and mucous membranes of drugs. It has anti-inflammatory, analgesic, antiseptic and fibrinolytic effect. The drug is able to restore antimicrobial activity of antibiotics relatively resistant or weakly sensitive bacteria strains.

Pharmacokinetics. When applining a solution (90%) of dimethyl sulfoxide on the skin, it is determined in the blood in 5 minutes, reaching a maximum concentration after 4-6 hours while maintaining the almost unchanged level for 1.5 - 3 days. Dimethyl sulfoxide is distinguished with urine and feces both in constant form and as dimethyl sulfone.

Indications for use. Dimmethyl sulfoxide is prescribed in the treatment of inflammatory diseases of the musculoskeletal system (rheumatoid arthritis, Bekhterev's disease, deforming osteoarthritis, arthropathy), with injuries, tensile ligaments, traumatic infiltrates, inflammatory edema, purulent wounds, abscesses, acute and chronic osteomyelitis, in the treatment of nodular erythema, Streptodermia, acne, corrosive inflammation, furunculosis, with folliculites and thrombophlebitis.

Method of application and dose. Dimethyl sulfoxide is applied externally as applications and irrigation (washing), as a rule, in aqueous solutions (30-50%) for tampons, compresses. Compress impose on the affected areas, capturing adjacent healthy skin. The dimethyl sulfoxide solution is wetted by gauze napkins, which impose on the affected areas once a day for 20-30 minutes. Polyethylene film and linen or wool fabric are superimposed on top of the napkin. The course of treatment is 10-15 days.

In the treatment of grinding inflammation and trophic Yazv The drug is used in the form of a 30-50% aqueous solution of 50-100 ml 2-3 times a day. With eczema, diffusion streptoderms are recommended compresses with 40-90% aqueous dimethyl sulfoxide solution. With mineral skin diseases, 40% solution is used.

In the treatment of deep burns, we use bandages with a 20-30% dimethyl sulfoxide solution (if necessary in a dose - up to 500 ml). In the skin-plastic surgery, bandages are used with 20-30% solution of the preparation. A 5% solution of dimethyl sulfoxide in Ringer's solution is used to preserve the skin homotransplants.

Side effect. Dimethyl sulfoxide is usually well tolerated, but some patients may occur erythema, itching, dizziness, insomnia, adamis, dermatitis, diarrhea. In some cases, with poor tolerability of dimethyl sulfoxide, nausea is observed, vomiting, bronchospasm.

Contraindications. Dimethyl sulfoxide is contraindicated in pronounced cardiovascular insufficiency and atherosclerosis, angina, violations of kidney and liver functions, stroke, comatose states, during pregnancy, during breastfeeding period (during treatment, it is necessary to stop breastfeeding), glaucoma, cataract.

Overdose. In case of overdose, signs of side effects are enhanced.

Cautions. With caution prescribe the drug of elderly patients and children under the age of 9 years old.

Dimethyl sulfoxide can be used in conjunction with non-steroidal anti-inflammatory agents with complex therapy of deforming ostearrosis and rheumatoid arthritis, in combination with antimicrobial means of local action (syntomicin liniment) - for the treatment of streptodermia, acne, face inflammation, furunculosis, folyculite and other skin diseases, in conjunction with Heparin - with thrombophlebitis.

To avoid the use of the drug during individual intolerance of dimethyl sulfoxide, it is recommended to carry out a sample tolerability: the drug is applied to the skin with a cotton swab. Sharp hyperemia, or itching is a contraindication for the use of dimethyl sulfoxide. At temperatures below 18 ° C, a crystallization of dimethyl sulfoxide is possible, which does not affect the quality of the drug. To melting crystals, it is necessary to carefully warm the bottle with a drug on a water bath (water temperature of about 60 ° C).

Interaction with other drugs. Dimethyl sulfoxide enhances the effect of ethanol (alcohol inhibits the removal of the drug) and insulin, acid acetylsalicylic acid, butadion; DiGitalis, Chinidin, Nitroglycerin, antibiotics (streptomycin, monomocinum, etc.), sensitizes the body to drugs for anesthesia. An increase in strengthening of both specific activity and toxicity should be taken into account medicines.

Storage conditions.
At temperatures from 15 ° C to 25 ° C, in the place protected from light.

The shelf life of the drug 3 years.
Do not use after the expiration date!

Leave terms. Without a doctor's prescription.

Packaging. 50 ml in dark glass bottles with an attachment in a pack.

Manufacturer. DP "Agrofirma" Yang, ChP "Yang".

Address. Ukraine, 13643, Zhytomyr region, Ruby district, p. Neminers
ul. Dzerzhinsky, 58.

Gross formula

Pharmacological group of substance dimethyl sulfoxide

Nonological Classification (ICD-10)

CAS code

Characteristics of the substance dimethyl sulfoxide

Colorless transparent liquid or colorless crystals melted at 18.5 ° C, with a specific odor. Gigroscopic. Mixed in all ratios with water and alcohol. Molecular weight - 78,13.

Pharmacology

It has a topistanisive, local anti-inflammatory, antimicrobial (antiseptic) and fibrinolytic effect. Quickly and well penetrates through biological membranes, incl. Through the skin and mucous membranes, increases their permeability for other drugs. Changes the sensitivity of microflora, resistant to antibiotics. In most cases, in combination with other medicinal substances (previously dissolving in it or apply it to the skin) for better and deeper penetrations of tissue (for example, with heparin in the treatment of thrombophlebitis, with glucocorticoids in the treatment of eczema, with antimicrobial drugs in the treatment of furunculose , sophisticated inflammation, acne, etc.).

Application of substance dimethyl sulfoxide

Rheumatoid arthritis, Bekhterev's disease, deforming osteoarthritis, reactive synovit, radiculitis, sclerodermia, noded erythema, discoomed red lupus, corrosive inflammation; bruises, stretching bundles, inflammatory swelling; Infiltrates (including traumatic); purulent wounds, burns, trophic ulcers, thrombophlebitis, eczema, acne, mouthless skin diseases (pyoderma, furunculosis - as part complex therapy); in the leather-plastic surgery - canning the skin homotransplants; In dentistry - inflammatory diseases maxillofacial region, salivary glands, periodontitis, pulpitis, periodontitis, arthritis and arthrosis of the temporomandibular joint.

Contraindications

Hypersensitivity, heavy hepatic and / or renal failure, myocardial infarction, angina, pronounced atherosclerosis, glaucoma, cataract, stroke, coma, pregnancy, breastfeeding.

Dimeksid - feedback

Good, time-tested powerful drug against inflammation and infection. They say that they are clogged by the warehouses of the Ministry of Defense in the case of multiple infected wounds.

In the signs of shallow infection of soft tissues (redness, pulsating pain), you can not wait for a surgeon with a scalpel, but simply make compresses with diluted in half a domexide. With the depth of "lounge" of infection to two sanithmeters, be sure that the dimexide will help.

In addition to the precinct therapist, I had a chance to cure Dimeksid at home the corrosive inflammation of the shin at the grandmother, which was refused to take the "ambulance".

Unlike the set of "home-grown" Russian drugs, Dimeksid is used in the production of serious pharmaceutical companies (Doluben from Mercle).

Dimexide helps to "drive" other drugs with mixing with them. Very good property with local treatment of inflammatory changes (can, for example, mix domexide with non-steroidal anti-inflammatory drugs).

The drug is definitely diluted, and if on the background of dilution still get itching and redness of the skin, you need to try to dilute even more.

My attitude to Domexide as a drug from baldness has not yet been developed. It is hard to imagine the application of undiluted Dimeksid on the scalp twice a day for 6 months. Let's see, time will show.

Dimexide (dimethyl sulfoxide) - "Classical" instructions for use:

Tradename:

Dimeksid

International UnPatented Name (MNN):

Dimethyl sulfoxide

Dosage form:

Concentrate for the preparation of the solution for outdoor use.

Description:

It is a colorless transparent liquid or colorless crystals odorless or with a weak specific smell. Gigroscopic.

Pharmacotherapeutic Group:

Anti-inflammatory agent for local application.

Pharmacological properties

Anti-inflammatory drug for outdoor use, inactivates hydroxyl radicals, improves the course of metabolic processes in the focus of inflammation. It also provides local, analgesic and antimicrobial effect; It has moderate fibrinolytic activity. Penetrates through the skin, mucous, shell of microbial cells (increases their sensitivity to antibiotics) and other biological membranes, increases their permeability for medicines.

Indications for use

As part of comprehensive therapy: diseases of the musculoskeletal system: rheumatoid arthritis, Bekhterev's disease (spondylitrite ankylosing), deforming osteoarthritis, reactive synovit; Limited sclerodermia, nodular erythema, discoomal red lupus, copies Stop, kelloid scars, thrombophlebitis, alopecia, eczema, face; bruises, tensile ligaments, traumatic infiltrates; Purulent wounds, burns, radiculitis, trophic ulcers, acne, furunculosis, in penetration surgery - canning the skin homotransplants.

Method of application and dose

Cash, in the form of applications and irrigation (washing). In the solution of the required concentration, marlie wipes are wetted and imposed on the affected areas within 20-30 minutes. Polyethylene film and cotton or linen fabrics are superimposed on top of the napkin or linen fabric - 10-15 days.

In the treatment of faces and trophic ulcers - in the form of a 30-50% solution of 50-100ml 2-3 times a day.

With eczema, diffuse streptoderms - compresses with 40-90% solution.

For local anesthesia with pain syndromes - 25-50% solution in the form of compresses at 100-150ml 2-3 times a day.

For the skin of the face, etc., 10-20-30% solutions are used for highly sensitive regions.

In leather-plastic surgery, we use bandages with 10-20% solution to transplanted skin auto and homotransplants immediately after operations and under the next days of the postoperative period to the resistant graft enrage.

As a preservative environment for storing skin homotransplants, 5% solution in Ringer's solution is used.

Less than concentrated solutions produce washing of purulent necrotic and inflammatory foci and cavities.

Contraindications

Hypersensitivity, heavy hepatic and / or renal failure, angina, pronounced atherosclerosis, glaucoma, cataract, stroke, coma, myocardial infarction pregnancy, lactation period.

Side effect

Allergic reactions, contact dermatitis, erythema, dry skin, easy burning itching dermatitis; Rarely - bronchospasm.

Interaction with other medicines

Increases the absorption and enhances the effect of ethanol, insulin, etc. medicines. Compatible with heparin, antibacterial agents, NSAIDs. Increases the sensitivity of microorganisms to aminoglycosida and beta-lactam antibiotics; Chloramphenicol, rifampicin, griseofullvin.

special instructions

Some patients feel the smell of garlic in the inhaled air.

Before applying the drug, it is necessary to carry out a sample tolerability to it.

For this, dimethyl sulfoxide is applied to the skin with a cotton swab in it; The appearance of hyperemia and pronounced itching testifies to hypersensitivity.

Storage conditions

At a temperature not higher than 25 ° C, in an inaccessible place for children.

Shelf life

2 years. Do not use after the expiration date.

Conditions of vacation from pharmacies

Dimekside - a new look at the instructions for use:

(This instruction is published on a serious pharmaceutical site Vidal.ru, but the author of our website has not yet understood how to treat this publication - whether it is a joke, whether the error of the vestors, or really a revolutionary new word in fundamental science on baldness).

Preparation for the treatment of alopecia (baldness).

pharmachologic effect

Indications

• focal alopecia (baldness) in adults.

Dosing mode

Externally. Before use, they shake and apply on the affected areas using a cotton swab by lighting (not lying!) Every day, 2 times a day - in the morning and in the evening.

Daily dose - from 1 to 5 g of solution, depending on the size of the baldness.

The duration of treatment depends on the prescription, the severity of the disease, age and is 3-6 months. If necessary, treatment is repeated.

Side effect

Dermatitis, burning, itching.

Contraindications

• hypersensitivity;
• suffered myocardial infarction;
• pregnancy;
• children's age (up to 15 years);
• elderly age (over 60 years old).

Doluben - Instructions for use:

Clinical and Pharmacological Group:

The drug with anti-inflammatory, anti-acud, analgesic, antithrombotic and improving regeneration of tissues by action for outdoor use.

pharmachologic effect

Combined drug for outdoor use. The effect of the drug is due to the active substances included in its composition: heparin sodium, decantenol, dimethyl sulfoxide.

Dimethyl sulfoxide is an anti-inflammatory, anti-acudative and local analgesic effect. Penetrates through biological membranes (including through the skin), contributes to a deeper penetration into the tissue of other components of the drug and at the same time used medicines.

Heparin - inactivating biogenic amines in tissue, manifests anti-inflammatory activity, improves microcirculation. Heparin brakes the effect of hyaluronidase and thereby effectively contributes to the regeneration of the connective tissue. After applying the drug quickly penetrates into the skin (already for the first hour after applying the gel, the concentration in the subjectable tissues corresponds to concentrations that are achieved after in / in the introduction of 5,000 meters of heparin).

Decpaantenol is an anti-inflammatory and dermatoprotective effect, improves epithelization and granulation processes, stimulates the regeneration of damaged tissues. After absorption turns into pantothenic acid, which is involved in numerous metabolic processes, being an integral part of Coenzyme A. due to improving epithelization and granulation processes contributes to the regeneration of damaged skin sections.

Pharmacokinetics

Data on pharmacokinetics of the drug Doluben is not provided.

Indications for the use of drug Doluben

• hematomas and inflammation of soft tissues, muscles, tendons, tendon vagina, ligaments after bruises, squeezing, injuries;
• neuralgia;
• injuries of joints with stretching or breaking ligaments;
• shoulder Pulp Periatritis, Epipudilite Shoulder ("Tennis player's elbow"), tendinites, tendovaginites, bursts;
• arthritis, deforming osteoarthritis (with accompanying periarticular tissue lesions);
• surface thrombophlebitis, trophic ulcers against the background of chronic venous insufficiency.

Dosing mode

The drug is applied by a thin layer on the affected areas of the skin or on the skin above the painful zone, trying to avoid applying the gel directly to wounds and abrasions.

In order to cover the entire surface of the injured knee joint, it is usually enough to squeeze a length of 3-4 cm from the gel strip.

The procedure is repeated 2-4 times a day for 7-10 days or before the disappearance of the symptoms of the disease (pain, edema, inflammation).

The patient must be warned that if for 10 days of application, Dauchen does not occur distinct improvement, you should consult a doctor.

Side effect

Local reactions: most often redness, itching, burning sensation (gradually passing during treatment).

Allergic reactions: sometimes skin reactions; In isolated cases, immediate allergic reactions (urticaria, swelling of quinque).

System reactions: In rare cases - the smell of garlic from the mouth, changing the taste sensations (disappearing in a few minutes).

Contraindications for the use of drug Dauchen

• severe liver disorders;
• severe renal impairment;
• bronchial asthma;
• pronounced violations from the cardiovascular system (including heavy angina, myocardial infarction, stroke, expressed general atherosclerosis);
• pregnancy;
• lactation period;
• children's age up to 5 years;
• increased sensitivity to the components of the drug.

The drug can not be applied to the mucous membranes (eyes, nose, mouth), or on damaged skin (incl. Condition after irradiation, heavy solar burns, fresh postoperative scars).

Application of drug Doluben during pregnancy and breastfeeding

The use of drug is contraindicated during pregnancy due to the lack of clinical data confirming the safety of dimethyl sulfoxide (part of the gel) during this period.

In experimental studies on animals, it was found that dimethyl sulfoxide has a teratogenic effect.

The use of doluchene during lactation is contraindicated, since dimethyl sulfoxide is distinguished with breast milk.

Application with violations of liver function

Contraindicated with severe liver function disorders.

Application with violations of the kidney function

Contraindicated with severe disorders of the kidney function.

special instructions

Before applying, the daisy should carefully clean the skin from dirt, cosmetics, other medicines and chemicals.

When using a bandage after applying, it is necessary to wait a few minutes so that the gel is mainly absorbed into the skin, and the alcohol (isopropanol) has evaporated. This is especially important in cases where the used bandage does not pass the air.

The drug in the area intensifying the integrity of the skin can cause a painful reaction due to the content in the composition of the isopropanol gel.

The drug is spent economically, quickly absorbed and leaves no fat traces on her skin or clothing.

When applying, purulene is an isopropanol that is espaired and has a cooling effect. This effect is enhanced by applying a gel stored in the refrigerator, or in the hot season (by increasing the evaporation of alcohol).

Doluben can be used in ionophoresis. Heparin, which is part of the gel, in relation to the pH of the skin is an anion. The application of the preparation under the cathode improves the penetration of heparin through the skin, while dimethyl sulfoxide exhibits synergism with the effect of electric current (anesthesia, decrease in local edema). When conducting ionophoresis, it should be borne in mind that electric shock treatment may cause local skin irritation. You should carefully comply with the instructions for the operation of the instruments and always pay attention to the sufficiency of the coating of the electrodes with a wet sponge.

Double is a good contact gel when conducting phophoresis. Dimethyl sulfoxide and heparin complement the therapeutic effect of ultrasound.

Overdose

To date, the cases of overdose of the drug is not described.

Medicinal interaction

In case of joint external use, Daucine significantly enhances the penetration of other drugs through the skin.

With the simultaneous use of drugs containing Sulindac (NSAIDs), the development of severe toxic reactions (peripheral neuropathy) is possible with a drug.

Conditions of vacation from pharmacies

The drug is approved for use as a means of OTC.

Terms and Storage Terms

The drug should be stored in an inaccessible place at temperatures not higher than 25 ° C. Shelf life - 3 years.

Dimethyl sulfoxide is a colorless liquid with crystals of a group of sulfoxides. Possessed hygroscopic properties. Produced in the form of fluid for external use, as well as as a cream. It has a small number of analogues.

The remedy can penetrate the biological membranes. Penetrated into the human body through the skin, the medication exhibits transport properties. It has antiseptic and analgesic effect. It has a fibrinolytic effect. Able to remove strong inflammation.

The drug with ease restores the antimicrobial effect of antibiotics. The components of the tools fall into the blood stream in five minutes after applying the solution to the skin. The maximum effect is achieved after four to six hours. It remains unchanged for one and a half or three days.

From the body, the unchanged type of dimethyl sulfone is displayed along with urine and malicious feces.

Manufacturer

Dimethylsulfoxidum medicine is produced in two countries by leading pharmaceutical companies:

• Company "Pharmaced" - Russian Federation;
• DP agrofirm "Yang" - Ukraine;
• PE agro-industry "Yang" - Ukraine.

It is necessary to send their claims to Ukraine to the Zhitomir region at the address: 13643, Ruzhinsky District, Nemirinsky village, Dzerzhinsky Street, House 58.

Clinical researches

Dedicated to the drug more than forty thousand research. The main pharmacological properties of the medicine in experimental and clinical medicine have been studied very well. Particular attention was paid to anti-inflammatory and bacteriostatic properties, a non-specific increase in the resistance of the human body, an increase in the pharmacological activity of the means. But the most difficult mechanism of its biological effect remains still not studied. It is worth noting that, despite the high competitive market, the study of the drug is still being conducted. Thanks to the absence of cumulation, wide pharmacological spectrum and low toxicity, the drug is considered the most effective in a line of similar means.

Pharmacists lay great hopes on DMSO, putting it on the "pedestal" of clinical medicine.

Forms of release and composition

The medicine is made in two form of release:

1. In the form of fluid intended for external use. Concentrate for the preparation of a solution for outdoor use can be purchased for 34-56 rubles. The active component of the medication is dimexide. Dimethyl sulfoxide is produced in glass bottles with a capacity of 100 milliliters. 100 ml accounts for 100 ml of the existing component.
2. In the form of ointments intended for applying skin. Cream can be purchased for 152-199 rubles. As well as in the liquid, the active component of the medication is a dimexide. At 100 grams of the medication accounts for 25 grams of dimethyl sulfoxide. The medicine is produced in aluminum tubes for 30 g. As auxiliary components, apply:

• Methylpagidroxybenzoate (nigigin) - 0.05 grams;
• Propilepagidroxybenzoate (nipazole) - 0.013 gr;
• Sodium carmellos (sodium carboxymethyl cellulose) - 2 g;
• Purified water - up to 100 gr.

Dosage, application scheme

The dimethyl sulfoxide solution must be breeding with distilled water in a 1: 1 ratio. It is used in the form of compresses, irrigation and appliques, impregnating cotton fabric. The dressings are superimposed on the problem areas of the skin. It is worth considering that the bandage must be several centimeters more than the volume of affected skin. It must capture a small part of healthy fabrics.

As a cotton fabric for compress, impregnated gauze bandages are used. They must be applied to the skin once a day. Maximum use of 30-40 minutes. From above, the cloth must be covered with a film. For this purpose, conventional polyethylene cellophanes are perfect. The top layer of the compress is wrapped in a wool cloth.

Instructions for use implies to select the concentration of the drug depending on the current disease:

• Ground inflammatory processes and trophic ulcers - a concentration ranges from 30 to 50%;
• Skin, as well as plastic surgery - from 20 to 30%;
• Deep painful burns - from 20 to 30%;
• Diseases extramitting pill - 40%;
• Streptodermia and eczema - from 40 to 90%.

Cream allowed to apply adult patients and adolescentswho has reached the twelve age. Specialists advise apply a smooth thin layer of medication directly to the affected area of \u200b\u200bthe skin. During the procedure, one or twice must be performed. The duration of the course of treatment is 7-14 days, depending on the degree of developing disease. Reuse means is possible only after a 9-11-day break. Ointment should not be rubbed from above of other previously applied to the skin of creams.

After applying, the affected skin is not recommended to close the cloth.

Indications

Both forms of medicine must be used to eliminate pain with complex therapy With developing diseases:

• Arthropathy;
• Damage to ligaments;
• Radiculitis;
• Rheumatoid arthritis;
• Noded erythema;
• Bekhterev's diseases;
• Treatment of bruises;
• Elimination of bruises;
• Deforming osteoarthrosis;
• Neuralgia of a trigeminal nerve;
• Traumatic infiltrates;
• Sclerodermia;
• Streptodermia;
• Thrombophlebitis;
• Furunculese;
• Acne;
• Abscesses;
• Osteomyelitis of acute and chronic form;
• Diseases causing inflammatory processes of skin.

Contraindications

The drug should not be applied in the following cases:

• With a developing angina;
• Myocardial infarction;
• Cardiovascular failure;
• Stroke;
• Pronounced arthrosclerosis;
• Glaucoma;
• Cataract;
• Comatous states.

In cases of what pain does not help?

Medication is allowed to apply in combination with antimicrobial drugs local action . This medicine has antiseptic, fibrinolytic effects. Easily relieves inflammation. Anesthetics. But the pain effect has a small and medium intensity.

The medicine will not cope with strong walking pains, unpleasant sensations of chronic character. Also, the solution and ointment is not recommended to be used in acute unbearable pain, immediately after receiving burns, wounds, breaks and stretching ligaments.

With extreme caution, it should be used to use people with pathologies of vision. It is forbidden to use gel and liquid with patients suffering from glaucoma and cataract.

With extreme caution, it is necessary to apply the drug to people suffering from diabetes mellitus. The active ingredient is capable of negatively affect the health of patients, causing a system failure.

During the course of treatment, it is strictly forbidden to take any alcoholic beverages. The main component is able to strengthen the effects of ethanol.

Alcohol products inhibits the removal of the medication. Therefore, an overdose can occur as well as signs of intoxication.

Nuances of application

It is strictly forbidden to apply pregnant girls. Main component Negatively affects the development of the fetus, causing the formation of pathologies and other negative properties. The medicine can provoke miscarriage or premature childbirth. The drug is used only in the case when the mother's life is rated above the life of a developing fetus.

The drug can not be given to persons under the twelve age. Therefore, the newborn children can reveal pathologies and dangerous diseases. Before applying the means, the baby must be translated into artificial nutrition.

With extreme caution, it is necessary to apply a means to small children, as well as adolescents under the twelve age. The active substance can adversely affect the growing organism. They can cause a slowdown in growth and development, the formation of pathologies of internal organs. Therefore, the use of the means should be refused. Teenagers older than twelve years during the course of treatment should be observed at a specialist.

With extreme caution, you should apply the cure for older persons over 65 years old. The active substance is derived from the body through excrement. In the elderly, the output of the main component can linger. Therefore, such people need to reduce the concentration of the solution, as well as the amount of gel. Otherwise, an overdose may occur.

Before use, consult with a qualified physician.

Overdose and side effects

During overdose, signs of side effects increase. Experts note that the patient is tolerated very well. In 95% of all cases, side effects do not occur. But in some cases, in the portability of the main component of dimethyl sulfoxide, patients may form a feeling of nausea, vomiting, bronchospasm. In rare cases, the following unpleasant properties may occur:

• Formation of erythema;
• Dizziness;
• Adamina;
• Dermatitis of itching and contact manifestation;
• Diarrhea;
• Dry skin dry;
• Easy burning;
• Sleep disturbance;
• Sense of anxiety.

Interaction with other medications

Instructions for use indicating that with extreme caution It is necessary to apply the medicine together with other medications. The drug is able to strengthen not only activity, but also toxicity of most drugs.

The medicine is compatible with heparin, non-steroidal anti-inflammatory agents, antibacterial drugs.

The drug increases the impact of insulin, aspirin and butadion. Enhances the effectiveness of digitalis, quinidine, nitroglycerin.

The medicine is capable of sensitizing the body to the means for anesthesia.

The drug is able to increase the sensitivity of microorganisms to aminoglycosidic and β-lactam antibiotics of a wide spectrum, as well as to rifampicin, chloramphenicol and griseofullvin.

Storage, vacation from pharmacies

Purchase the drug is possible without providing a recipe form from a specialist. The shelf life of fluid and cream is three years. Store the drug is necessary at a temperature not exceeding 15-25 ° C. It is worth noting that at temperatures below 18 ° C in a glass bottle, crystall-shaped particles may fall.

Therefore, in this case, before applying, the medicine must be hampered a little on a water bath or in a little warm water.

Analogs

It is worth noting that the drug has a small amount of analogues, as it has a wide range of action.

Unlike other means, the medicine covers anti-inflammatory, antiseptic and analgesic effect.

Synonyms

General characteristics:
international UnPatented Name: Dimethylsulfoxidum;
basic physico-chemical properties: Colorless liquid or colorless crystals. Gigroscopic.

structure:
active substance: dimethyl sulfoxide is not less than 99%.

Release form. Liquid for outdoor use.

Pharmacotherapeutic group.
Funds used locally with articular and muscle pain. PBX code: M02A x03.

Pharmacological properties.
Pharmacodynamics. Dimethyl sulfoxide penetrates well through biological membranes, including through the skin and exhibits transport properties, contributing to penetration through the skin and mucous membranes of drugs. It has anti-inflammatory, analgesic, antiseptic and fibrinolytic effect. The drug is able to restore antimicrobial activity of antibiotics relatively resistant or weakly sensitive bacteria strains.

Pharmacokinetics. When applining a solution (90%) of dimethyl sulfoxide on the skin, it is determined in the blood in 5 minutes, reaching a maximum concentration after 4-6 hours while maintaining the almost unchanged level for 1.5 - 3 days. Dimethyl sulfoxide is distinguished with urine and feces both in constant form and as dimethyl sulfone.

Indications for use. Dimmethyl sulfoxide is prescribed in the treatment of inflammatory diseases of the musculoskeletal system (rheumatoid arthritis, Bekhterev's disease, deforming osteoarthritis, arthropathy), with injuries, tensile ligaments, traumatic infiltrates, inflammatory edema, purulent wounds, abscesses, acute and chronic osteomyelitis, in the treatment of nodular erythema, Streptodermia, acne, corrosive inflammation, furunculosis, with folliculites and thrombophlebitis.

Method of application and dose. Dimethyl sulfoxide is applied externally as applications and irrigation (washing), as a rule, in aqueous solutions (30-50%) for tampons, compresses. Compress impose on the affected areas, capturing adjacent healthy skin. The dimethyl sulfoxide solution is wetted by gauze napkins, which impose on the affected areas once a day for 20-30 minutes. Polyethylene film and linen or wool fabric are superimposed on top of the napkin. The course of treatment is 10-15 days.

In the treatment of grinding inflammation and trophic ulcers, the drug is used in the form of a 30-50% aqueous solution of 50-100 ml 2-3 times a day. With eczema, diffusion streptoderms are recommended compresses from 40-90% aqueous solution dimethyl sulfoxide. With mineral skin diseases, 40% solution is used.

In the treatment of deep burns, we use bandages with a 20-30% dimethyl sulfoxide solution (if necessary in a dose - up to 500 ml). In the skin-plastic surgery, bandages are used with 20-30% solution of the preparation. A 5% solution of dimethyl sulfoxide in Ringer's solution is used to preserve the skin homotransplants.

Side effect. Dimethyl sulfoxide is usually well tolerated, but some patients may occur erythema, itching, dizziness, insomnia, adamis, dermatitis, diarrhea. In some cases, with poor tolerability of dimethyl sulfoxide, nausea is observed, vomiting, bronchospasm.

Contraindications. Dimethyl sulfoxide is contraindicated in pronounced cardiovascular insufficiency and atherosclerosis, angina, violations of kidney and liver functions, stroke, comatose states, during pregnancy, during breastfeeding period (during treatment, it is necessary to stop breastfeeding), glaucoma, cataract.

Overdose. In case of overdose, signs of side effects are enhanced.

Cautions. With caution prescribe the drug of elderly patients and children under the age of 9 years old.

Dimethyl sulfoxide can be used in conjunction with non-steroidal anti-inflammatory agents with complex therapy of deforming ostearrosis and rheumatoid arthritis, in combination with antimicrobial means of local action (syntomicin liniment) - for the treatment of streptodermia, acne, inflammation, furunculosis, folitic and other skin disease, in a compound with heparin - with thrombophlebitis.

To avoid the use of the drug during individual intolerance of dimethyl sulfoxide, it is recommended to carry out a sample tolerability: the drug is applied to the skin with a cotton swab. Sharp hyperemia, or itching is a contraindication for the use of dimethyl sulfoxide. At temperatures below 18 ° C, a crystallization of dimethyl sulfoxide is possible, which does not affect the quality of the drug. To melting crystals, it is necessary to carefully warm the bottle with a drug on a water bath (water temperature of about 60 ° C).

Interaction with other drugs. Dimethyl sulfoxide enhances the effect of ethanol (alcohol inhibits the removal of the drug) and insulin, acid acetylsalicylic acid, butadion; DiGitalis, Chinidin, Nitroglycerin, antibiotics (streptomycin, monomocinum, etc.), sensitizes the body to drugs for anesthesia. Increases the preparation of both specific activity and toxicity of drugs.

Storage conditions.
At temperatures from 15 ° C to 25 ° C, in the place protected from light.

The shelf life of the drug 3 years.
Do not use after the expiration date!

Leave terms. Without a doctor's prescription.

Packaging. 50 ml in dark glass bottles with an attachment in a pack.

Manufacturer. DP "Agrofirma" Yang, ChP "Yang".

Address. Ukraine, 13643, Zhytomyr region, Ruby district, p. Neminers
ul. Dzerzhinsky, 58.

Dimmethyl sulfoxide is a drug that is intended to eliminate pain and inflammatory reactions in the joints of the joints. The drug is produced in fluid for outdoor use. The instruction on the use of dimethyl sulfoxide includes all the necessary information for the patient. However, before using the medication, it is still recommended to consult with a specialist.

Dimethyl sulfoxide is prescribed with different pathologies of muscle tissues and diarrosis. Treatment of a particular disease is carried out in compliance with the required dosages of the drug. The drug allows you to fight the listed ailments:

• inflammatory processes in the joints;
• signs of rheumatoid arthritis;
• arthropathy;
• traumatic consequences;
• inflammatory deterioration of the skin;
• nodular erythema;
• essential bruises with the manifestation of strong pains of pain;
• wounds with purulent formations.

Method of use of drug

Drug is intended for outdoor use. It is possible to use a dimethyl sulfoxide solution for washing the resulting wounds or for the manufacture of compress. With the help of compresses, the affected body of the body is heating.To do this, moisten the gauze solution medicinal preparation. To create a better warming effect, a food film or warm fabric is superimposed on top of gauze. Solution healthy plot Skin cover is not accompanied by a negative effect.

To handle ulcers on the skin should be used fifty percentage solution Dimethyl sulfoxide. For its preparation, it is necessary to dilute the drug with water in the proportion of one to one. Processing wounds must be performed three times a day. Therapy will require 50 ml of dosage consistency.

To eliminate signs of pain in muscles or joints, as well as for the processing of open wounds, you will need 100 ml of solution. To do this, it is necessary to use dimethyl sulfoxide twice a day.

Apply a means to the skin is necessary for a period of time from 10 to 30 minutes. The course of treatment can be from 10 to 15 procedures.

Pharmacodynamics

Medicinal components included in the drug under consideration are capable of penetrating the skin quickly. They have anti-inflammatory, anesthetic, antiseptic effect on the affected area.

The first active components of the drug in blood occurs after five minutes. The maximum concentration in the blood is observed after passing the time from four to six hours, while maintaining the level achieved for three days. The output of dimethyl sulfoxide components from the body occurs naturally.

Contraindications

The use of the drug by the elderly and children in the age group before nine years should be carried out with caution. The use of dimethyl sulfoxide is contraindicated when observed:

1. cardiovascular failure;
2. glaucoma or cataracts;
3. period of pregnancy;
4. atherosclerosis;
5. myocardial infarction;
6. stroke;
7. lactation period;
8. angina;
9. kidney dysfunctions, liver;
10. comatous states.

Probable side manifestations

With clinical trials of the drug, possible side effects are installed. Their manifestation is associated with the individual characteristics of the human body that does not accept individual components medicinal solution. Perhaps the manifestation of the following side Effects:

• signs of severe itching at the place of treatment of the skin;
• dizziness;
• periodic insomnia;
• erythema;
• dermatitis;
• vomit urge and nausea;
• disorders of the gastrointestinal tract;
• complications of bronchial asthma.

Overdose

Application of an excessive amount of dimethyl sulfoxide on the skin leads to a manifestation of an allergic reaction. It is accompanied by the formation of rash, burns on the skin and redness.In such situations, it is necessary to immediately rinse the treated area of \u200b\u200bthe skin and stop using the drug. The elimination of this symptomatology is carried out by receiving antihistamine drugs, which the doctor should appoint.

Storage conditions

Store dimethyl sulfoxide is necessary at a plus temperature from 16 to 25 degrees. The drug must be in a place not affordable for children. In case of random oral medication, poisoning can occur. When observing a slight crystallization of the solution, it is necessary to heat it in warm water. The drug retains its properties for three years from the moment of manufacture.

Interaction with other drugs

Dimethylsulfoxide is recommended not to combine with other types of external use preparations. The components that make up the drug contribute to strengthening the effect of alcohol, insulin, acetylsalicylic acid, nitroglycerin and antibiotics. Dimethyl sulfoxide can also lead to an increase in the toxicity of individual drugs.

Complex use of the drug is permissible for arthritis therapy and osteoarthrosis. It is used in combination with non-steroidal anti-inflammatory means. In treating different species Skin diseases are used in conjunction with antimicrobial preparations.

special instructions

Before the direct use of the solution, you should check the response of the body to the drug. To do this, you need to moisten a cotton swab with a small amount of medicinal solution and apply to the back of the palm. The formation of the burning or redness of the skin does not indicate the skin hypersensitivity to the components of the drug. In this case, use the drug is prohibited.

Some people may not endure the smell of dimethyl sulfoxide, which leads to nausea and vomit.

Price

Dimethyl sulfoxide is for sale in any pharmacy without a doctor's prescription. The average cost of the medicine - 80-120 rubles.

Chondroxide Forte - a combined drug for outdoor use, which is actively used in rheumatology, traumatology, orthopedics. It has an anti-inflammatory and analgesic effect, eliminates swelling and hematoma. Cream Chondroxide Forte is prescribed to patients with radiculitis, osteochondroses, arthritis, intervertebral hernias. Currency use of the drug prevents further destruction of the articular structures.

The ingredients of the cream complement each other, the therapeutic properties are mutually reinforced and prolong. But multicomponent composition significantly expands the list of contraindications to the use of chondroxide forte. Before starting treatment, you must consult with your doctor about the feasibility and safety of its use.

Composition and form of release

Cream Chondroxide Forte (from 350 rubles) is produced by the domestic producer of NIPARM. Primary packaging is an aluminum and plastic tube. Each of them is 10.0 g, 20.0 g, 25.0 g, 30.0 g, 50.0 g or 100.0 g of the drug. Secondary packaging is a cardboard box with an internal annotation. The cream is a dense substance of greenish yellow color with a specific smell of dimexide. It includes such active ingredients:

• chondroitine sulfate;
• meloxicam;
• dimethyl sulfoxide.

For the formation of the ointment base, vaseline oil, distilled water and vaseline are used. To ensure maximum transdermal absorption, macroogol, imidochevine, cetyl and stearyl alcohols have been added to the cream. The auxiliary component of propylene glycol creates a pH level corresponding to human skin acidity.

The shelf life of Chondroxide Forte - 24 months. After opening the tube, it is reduced to 4 weeks. The preparation is subject to storage in a dark place at a temperature not higher than 20 ° C. It is not suitable for use when changing its consistency, color or smell.

pharmachologic effect

Chondroxide Forte - Drug pharmachologic effect which is based on the properties of the components. Its combined clinical efficacy is to slow down the progression of the disease, the manifestation of analgesic and anti-ethosity activity. The preparation includes such components:

• meloxico - Nonteroid anti-inflammatory agent;
• chondroitine sulfate is a tissue regeneration stimulator, chondroprotector;
• dimethyl sulfoxide is a fibrinolytic and analgesic, providing a penetration of chondroitin.

After the course use of the drug, the volume of movements in the joint is restored, its morning swelling disappears. The severity of anesthetic effect increases as the chondroprotector in the tissues.

Chondroitina Sulfat

The mechanism of action of chondroitin sulfate is based on physico-chemical, but on the biological properties of its molecules. It participates in the construction of hyalinic cartilage, stimulates anabolic processes. What is still useful chondroitin:

• increases proteoglycan synthesis;
• increases the production of hyaluronic acid;
• inhibits enzymes that cause the destruction of the articular tissues;
• slows the processes of catabolism;
• prevents the formation of free radicals;
• warns the death of chondrocytes.

Chondroitin sulfate as part of Chondroxide Forte is cumulated in the articular structures. A few days later, he begins to show analgesic activity. This allows you to reduce dosages of nonsteroidal anti-inflammatory funds, minimize the likelihood of damage to the mucous membranes of the gastrointestinal tract.

In St. Petersburg State University, studies were conducted to study the effects of chondroitin on synovial fluid. It was found that the use of chondroprotector in the treatment normalized metabolic processes in the articular fluid. The anti-inflammatory effect of the compound and its ability to stop destructive degenerative changes was confirmed.

Meloxicam

Meloxicami is a representative of a group of non-steroidal anti-inflammatory funds. These drugs prevent the development of the inflammatory process, reduce its intensity, exhibit painkillers and antipirective activity. Meloxicams in the chondroxide forte is used to treat the pathologies of the joints and the okolossertable tissues. It inhibits the cyclooxygenase enzyme and producing pain mediators, inflammation and febrile states - prostaglandins.

The result is the weakening of the symptoms of articular diseases, the suppression of exudative phenomena. Gradually restores the volume of movements, their morning stiffness disappears.

Meloxicami is one of their safest drugs from the NSAID group. It does not have a pronounced toxic impact on the kidneys, liver, gastrointestinal tract.

Dimeksid

Dimethyl sulfoxide in the form of a solution and ointments is used to treat diseases of the joints and spine. It suppresses the activity of hydroxyl radicals, accelerates the metabolism in an inflammatory focus. Dimexide has the following pharmacological properties:

• antiseptic;
• fibrinolytic;
• topless;
• analgesic.

Dimethyl sulfoxide stimulates the formation of fibrin, normalizes microcirculation. The use of Chondroxide Forte eliminates platelet aggregation. In the inflammation of the tissues, blood circulation is normalized, the reserves of trace elements, nutrient and biologically active substances are replenished. Dimethyl sulfoxide optimizes permeability blood vessels, Provides maximum absorption of other ingredients Chondroxide Forte.

Indications for use

Chondroxide forte is prescribed to patients with diseases of the musculoskeletal system, complicating pain syndrome. Its particularly relevant application in pathological therapy, accompanied by destructive-degenerative changes in the joints:

More details

• arthrosis, Osteoarthritis;
• chest, cervical, lumbosacral osteochondrosis;
• juvenile, rheumatoid, psoriatic arthritis;
• sinovit's shoulder, hip, knee Sustava;
• baker's cyst, bursitis;
• gout;
• intervertebral hernia;
• spondyltrosis.

The cream is recommended by doctors to use to accelerate recovery after injuries - bruises, sprains, dislocations, subway, fractures. Use Chondroxide Forte helps reduce the duration of the rehabilitation period.

Contraindications

The drug is not prescribed to patients when identifying individual intolerance to the active or auxiliary ingredient. To contraindications, Chondroxide Forte also includes:

• breastfeeding period;
• the existence on the skin in the proposed region of applying cracks, open wound surfaces, abrasion;
• pregnancy.

The medicinal product includes meloxico from a group of non-steroidal anti-inflammatory drugs. It is capable of penetrating the systemic bloodstream and provoke side manifestations. Therefore, patients with gastritis and ulcerative lesions of the gastrointestinal tract are taking treatment of chondroxide cream under medical control.

The drug should be used in low dosages patients with cardiovascular pathologies, diseases of the liver and organs of the urogenital system. In pediatrics, it is used to treat children over 12 years old.

Side effects

Perhaps the development of a local allergic reaction. It is clinically manifested in the form of rash, redness and edema of the epidermis, skin itch. The occurrence of any side effect becomes a signal to cancel the drug.

For chondroxide, forte is characterized by low absorption of active substances in the bloodstream. There were no system side effects during the use of cream.

Instructions for use

Chondroxide Forte is used for local application. It is not intended for occlusal dressings, but can be applied with fixing bandages. The cream is applied with a thin layer a little higher than the inflammation area, and then rubs into the skin. Motherwise dose It depends on the site of painful sensations and is 1-5 cm strips of means extruded from tube.

Treatment of joints More \u003e\u003e

The duration of the therapeutic course is determined by a rheumatologist or traumatologist. The doctor takes into account the degree of destructive degenerative changes and the presence of chronic pathologies in history. After 2 weeks, the clinical efficacy of the drug is estimated. If necessary, its use can be continued.

special instructions

In case of accidental hit, Chondroxide Forte on the open wound surfaces or mucous membranes should be rinsed under the stream of clean water. Application on extensive areas of the skin can cause the development of side manifestations.

During treatment, there are no neurological disorders, so driving vehicles and mechanisms management is not prohibited. The use of the drug does not have a negative impact on memory, the concentration of attention and the reaction rate.

Chondroxide Forte in Capsules in the therapy of the joints

The Indian manufacturer produces chondroxide forte in capsules (about 300 rubles) for the treatment of diseases of the joints and a binder-tendonal apparatus. They are packaged into blisters from aluminum foil for 10 pieces. In the secondary package - a cardboard box - there are 30 capsules. A biologically active additive is intended to regulate the tissue exchange and stimulation of the regeneration of the articular structures. It includes the following active ingredients:

• glucosamine. Protects hyaline cartilage from metabolic damage, stimulates the production of the matrix. The structural and modifying properties of glucosamine ensures its ability to accelerate the production of chondrocytes;
• chondroitin. Additional substrate for the formation of a cartilage matrix. Stimulates the formation of hyaluronic acid by inhibiting hyaluronidase. Improves the properties of the synovial fluid, stimulates it to work out;
• ascorbic acid and tocopherol. Zhiro- I. water soluble vitamins Expose antioxidant activity. Destroy free radicals, warn the destruction of the joint, increase local immunity.

The biodowder also contains essential phospholipids that restore and strengthening cells. The daily dosage of chondroxide forte is 3-6 capsules. Bad is prescribed to patients with tendovaginites, bursitis, osteoporosis, spondylo-archites. Course intake capsules contributes to the formation of bone corn after fractures.

Despite the fact that Chondroxide Forte is subject to non-prescription leave from pharmacies, it is impossible to use it without appointing a rheumatologist or traumatologist. It contains active ingredients whose impact may worsen well-being and provoke side manifestations. Cream Chondroxide is a symptomatic agent used only in complex therapy.

Treatment of many orthopedic diseases requires full symptomatic therapy. Diseases of the joints, bones and ligaments often proceed with the development of inflammatory syndrome and intense pain.

It is typical for such a state as the heel spur. A large number of patients do not resort to surgical treatment Problems. Under these conditions, medication therapy of the disease begins to acquire a key role.

Heel spur

Before disassembling the symptoms of the disease and their targeted treatment, it is worth saying a few words about the pathology itself.

Due to the inflammatory process of various reasons in the region of the heel bone, compensatory bone growths begin to occur - osteophytes.

These bone spikes, overlooking each other, form a single structure, which was called the "heel spur".

The disease can be caused by the following factors:

1. Exchange diseases of the body, for example, gout.
2. Arthritis.
3. Deforming arthrosis of an ankle joint.
4. Injuries of the heel bone.
5. Voltage of the ligament apparatus of the foot with long-term flatfoot.
6. Congenital developmental anomalies.

Promote the development of spurs on the heels intensive loads on the foot in athletes, overweight and diseases leading to circulatory disorders in the lower limb.

Now knowing the causes and factors of the development of pathology should be remembered on them at the stage of treatment.

In addition to use drugs, You should change the lifestyle, eliminate additional damaging stop factors.

Symptoms

Medical treatment of heel spurs is based on the symptomatic principle. At the existing symptoms of the disease, the doctor prescribes the appropriate drugs. To cure the spur on the heels only with pills or ointments it is impossible, an operation is most often necessary for the complete elimination of the problem.

What symptoms most often accompany pathology? These include the following manifestations of the disease:

• Intensive pain in the heels, on the back surface of the ankle joint. This is the main sign of pathology, is associated with the formation of inflammatory infiltrate in this area. The pain is intensified when walking in close shoes.
• The edema of the ankle joint and the region of the heel bone is another sign of inflammation. Additionally increases the volume of the limb, making it difficult to move and choose shoes.
• Redness of the skin over the joint and local temperature increase.
• Difficulty movements in the joint. This feature is associated with inflammatory edema of the cavity of the foot joints and painful syndrome. The patient tries to load the sore feet as little as possible.
• Resistant deformation of the bone - formed gradually, closer to the last stages of the disease. On the rear surface of the heel bone, an increase in bone tissue is formed, which cannot be eliminated by anti-inflammatory agents.

Knowing the main symptoms of spurs on the heels, it is possible to choose the appropriate drug therapy.

Medicia treatment

Until now, there is no accurate scheme of therapy of such a state, like heel spur, medication treatment picks up the doctor individually, based on the patient's peculiarities.

It is possible to treat pathology using the following groups of drugs:

1. Non-steroidal anti-inflammatory funds (NSAIDs).
2. Hormonal medicines - glucocorticosteroids.
3. Various vegetable preparations.
4. Local anesthetics in patches or ointments.

The main groups of drugs should be disassembled in more detail in order to understand when the disease should be treated with each of these drugs.

Each group of funds has contraindications, features of use and side effects. Use pills, ointments, plasters without appointing a doctor not recommended.

Medicines will bring the best effect when complying with the instructions for use, as well as combining drug therapy with other methods of treatment. Additional method of therapy will be said below.

Get ready to treat the disease indefinitely long. It is necessary to follow the instructions of a specialist to speed up the remission of pathology.

NSAID

The most popular group of symptomatic anti-inflammatory drugs in rheumatology and orthopedics are nonteroidal products. The NSAIDs have a pronounced effect and a small number of side effects that can be successfully presented.

Examples of drugs from non-steroidal agents:

• Diclofenac.
• Ibuprofen.
• Ketoprofen.
• Nimesil.
• Meloxico.
• Codexib.
• Ryricoxib.

These medicines are widely known and are used to patients wide enough. NSAIDs with heel spurs reduce the intensity of the inflammatory response. This leads to the following effects:

1. The severity of pain decreases, the performance and quality of the patient's life increases.
2. Employed swelling in the articulation area.
3. The rate of osteophyte growth is reduced in the absence of an inflammatory reaction.

Such effects will be useful for all patients with heel spur. However, non-steroidal funds have a number of shortcomings.

NSAIDs cannot be used to people with the following states:

• Allergic reactions to drugs of this group.
• Blood diseases.
• Yazzen lesions of the mucous membrane of the digestive organs.
• Aspirin bronchial asthma.
• On the last trimension of pregnancy.

In the cases listed, the concomitant pathology comes to the fore, and the treatment of heel spurs becomes a secondary problem.

If the patient is not prohibited by the reception of non-steroidal drugs, the doctor prescribed one of the drugs of this group, you should pay attention to some features of the application:

1. The greatest effect is achieved when using tablets and injections, but these forms are connected with a large number of adverse reactions.
2. When using systemic forms of drugs, it is necessary to protect the gastric mucosa - simultaneously taking proton pump inhibitors to appoint a doctor.
3. It should not be used inside at the same time several NSAIDs - this increases the risk of complications. Possible combination of tablets and outdoor forms.
4. NSAIDs are produced in a large number of dosage forms. Perhaps, for the treatment of heel spurs, you will be quite exclusively ointments. Compare this option with your doctor.

Corticosteroids

Hormonal preparations for the treatment of inflammatory syndrome in the joints of the joints today are used in the form of intra-articular injections and outdoor forms (ointments and gels).

The introduction of a hormonal agent into the hollow of the joint is called the blockade. This achieved pronounced therapeutic effect as soon as possible. The indication is inflammation in the heel spur, which is not removed by the reception of other medicines. Diprosspan is introduced into the body cavity, repeating procedures are too often impossible. The minimum period between two injections is 7 days.

Another application method hormonal drugs - Use of outdoor forms. Very popular creams, ointments and hydrocortisone-based gels. This method of applying drugs avoids the side effects of hormonal means and reduce the severity of local inflammation.

Mazi with hydrocortisone is applied to the area of \u200b\u200bthe heel spur twice a day for two weeks. A combination with a systemic method of nonsteroidal agents is possible.

Contraindications for the use of hydrocortisone:

• Previous surgery.
• Damaged skin coverings in the place of application.
• Pregnancy and breastfeeding.
• Skin diseases.

In these cases, funds will have to refuse.

Vegetable preparations

Today the pharmaceutical market offers a large amount of natural agents for treatment various diseases. One of these drugs is cream heel spur.

This tool contains the following components:

1. Lop oil.
2. Khrena extract.
3. Lilac extract.
4. Alcohols of fatty acids.
5. Beeswax.
6. Lemon oil, juniper.
7. Short extract.

Such a set of natural components is designed not only to reduce the intensity of inflammation, but also to achieve additional effects:

• Soften the skin in the place of application.
• Improve blood supply in the area of \u200b\u200bdamage.
• Prevent the development of infectious complications while simultaneously using orthopedic stelks.

Apply the drug follows:

1. A small amount of cream is applied to clean the foot.
2. It is necessary to make the apparatus to the skin within a few minutes.
3. Repeat the procedure 2-3 times a day.
4. It is possible to use after salt baths, while wearing a stelc.

Use the medicine should be carefully. A large number of active ingredients It can cause allergies and other unwanted effects. Consult with your attending physician before use.

Local anesthetics

Funds for local anesthesia can be divided into several groups. The first includes anesthetics, for example, Novocaine. The second is local anti-inflammatory agents - dimethyl sulfoxide.

Novocaine does not affect the intensity of the inflammatory response. This means acts solely on the nerve endings, interrupting pain impulse from the place of damage. As a result, the intensity of pain decreases, human performance increases. Novocaine is used as a solution for electrophoresis.

Dimethyl sulfoxide is contained in the composition of the means of dimexide. This drug is used in the form of appliques with napkins after pre-impregnation with a solution with a solution.

The drug reduces inflammation intensity, improves tissue reduction processes, causes a decrease in pain syndrome. The drug is used for no more than 14 days.

Plasters from heel spurs

Widespread use has found such a method for treating heel spurs as a plaster. There is a large number of different funds in this dosage form.

Plockers may contain as part of:

• Pepper extract.
• Tincture of Arnica.
• Lanolin.
• Pine rosin.
• Rubber.
• Balaladon extract.
• Wheat flour.

Natural components are designed to reduce inflammation intensity without causing side effects. A manifestation of an allergic reaction to the use of the drug is possible. In this case, the use of the patch should be refused.

Before using such funds, you should consult a doctor.

Other treatments

Remember, the use of exclusively drugs can reduce the intensity of symptoms, but not more. Influence the disease, you can influence the auxiliary methods of therapy:

1. Medical gymnastics.
2. Massage.
3. Different methods of physiotherapy.
4. Sanatorium treatment.
5. Wearing orthopedic products.

It is important to find and eliminate the cause of the formation of the heel spur.

If all conservative events did not bring effect, doctors resort to surgical removal of spurs. After the operation, the patient passes the rehabilitation course and returns to everyday life.

How to make compresses with Dimeksid: instructions for use

Treatment of many diseases requires an integrated approach. Pain in the joints and neuralgic manifestations of osteochondrosis are often forced to apply various compresses, rubbing.

Most effective tool For use in such procedures, dimexide is considered. It significantly relieves pain and has an anti-inflammatory effect. How to make compresses with Dimeksid, we learn from the article.

• Domexide and its properties
  • Methods of using Dimeksida
• Instructions for use
  • Contraindications for application

Domexide and its properties

This medicinal product is a transparent liquid with colorless crystals. It has a characteristic smell resembling the aroma of garlic, which is quickly disappeared.

The main operating component in the composition of dimexide is dimethyl sulfoxide. Its concentration in the preparation depends on the form of the release of Dimekside. In liquid form, its concentration is usually from 10 to 90% per 100 grams.

The drug is used only locally, it should be applied to problem areas of the body. Domexide has unique properties, so it is often used at home as a means for compresses.

Molecules of substances quickly penetrate into the skin and begin to act in the focus of inflammation. This property is not for the power of other drugs. And the dimexide has other properties:

• anti-inflammatory and painkillers;
• antifungal effect;
• activation exchange processes in articular tissues;
• regeneration of damaged sites.

The drug has long been used for compresses. Usually it is prescribed to children and adult people with the following problems:

• Skin infectious diseases.
• Various bruises of the articular parts of the body.
• Fungal lesions on the skin.
• Radiculites and damage to ligaments.
• Hematoma.
• Inflammation of respiratory organs.

All procedures should be performed only by appointment of a doctor. The drug has its own healing properties, but also contraindications. It should be used correctly and then the drug will benefit health.

Methods of using Dimeksida

This medicine is often used to treat arthrosis. With it, it is possible to slow down the degenerative processes occurring in the joints. After the course of procedures with a solution of Dimeksid, the condition is much facilitated. And also it helps to remove pain after knee injuries or elbow and other parts of the body.

The most effectively dimexide helps if it is used in the composition with Novocaine. Such a compress will get rid of pain in the muscles and joints. Novocaine has excellent anesthetic properties and is not a toxic drug. Novocaine helps to relax the heart, muscle system and reduce sensitivity.

To get the maximum therapeutic effect of compresses, with the healing solution should be completed from 10 procedures, daily, without interruptions. Be sure to pay attention to the concentration of funds.

Before use, it is desirable to check the body's reaction to the domexide. To do this, it is best to spend a special sample. It is necessary to take a cotton swab, moisten it in Domexide and attach to a portion of the body for several minutes. If signs of redness, irritation or itching appeared on the skin, then it can be used for compresses.

For the treatment of inflamed joints, musculoskeletal system, bruises, hematomas It is recommended to use a 20-50% solution of dimexide. It can not be applied in its pure form, since it causes burns in an undersedized. To do this, it is bold with warm boiled or distilled water. In the treatment of joints, dimexide is diluted with half water.

There are several methods for preparing compresses at home. Dimexide for the treatment of joints can be used with next drugs: Novocaine; hydrocortisone; Diclofenac.

They are applied depending on the pain and type of disease. To remove pain better use for novocain compresses with dimexide. To do this, take the following components:

1. Novocaine 20% - 50 ml.
2. Domexide - 30 ml.
3. Water - 50 ml.

To remove inflammation in the joints, it is desirable to use hydrocortisone. Such compress is applied to the sore joint. Drugs are taken in the following proportions:

• dimexide - 50 ml;
• water - 30 ml;
• hydrocortisone - 1 ampoule.

For patients with joints, dimexide, diluted with water in equal parts, is also used. It is added to 1 ampoule diclofenac. The compress has an anti-inflammatory effect and if we add lidocaine (1-2 ampoules) to such a composition, then it will have an anesthetic effect.

Instructions for use

Prepare a means for compress needed in rubber gloves, since Dimexide may cause irritation. The prepared solution for the compress can not be kept too long and rub it into the surface of the skin. For compresses from Dimexide, it is desirable to use a gauze tissue.

After preparing the solution, it should be moistened in it with a gauze napkin and attach it to the affected body. From above, it is necessary to put polyethylene or waterproof paper, then the wool layer.

It is desirable that the wool layer was a thickness of at least 1-2 cm and the dimensions were a little more marlevary napkin. All compress must be fixed using a bandage. It is recommended to make such procedures 1 time per day, putting on the affected joint knee, elbow or other affected areas of the joints.

More than 50 minutes to keep the compress is not desirable not to cause irritation, redness on the skin. After cooking, it should be immediately used. If you do in advance, then after a few hours, the healing properties of the solution will disappear.

Contraindications for application

Dimeskin must be applied only by appointment of a doctor. If used together with other medicines, it becomes potent tool. Such properties help in the treatment of many diseases, but if improper use can harm health.

Description of the dosage form

Uniform, transparent or almost transparent gel from colorless to light yellow color, with a specific smell. The presence of air bubbles is allowed.

Structure

1 g of gel contains 250 mg or 500 mg of dimethyl sulfoxide as an active substance.

Restfarms: Carbomer, Diethanolamine, Menthol racemic, purified water.

Pharmacotherapeutic group

Other means for local use with pain in the joints and muscles.

Indications for use

It is used to remove pain syndrome with complex therapy of rheumatoid arthritis, diseases of Behterev, deforming osteoarthritis, artopathy, radiculitis, for the treatment of bruises, damage to ligaments, traumatic infiltrates, with the treatment of noded erythema.

Method of application and dosage

Externally. Adults and children over 12 years old drugs are applied by a thin layer on the affected area 1-2 times a day and are easily triturated. For use on sensitive areas, dimexide, gel for outdoor use 250 mg / g. The duration of treatment is 10-14 days. Repeated courses can be carried out at least 10 days.

Side effect

Usually the drug is well tolerated, but the part of the patients may appear allergic reactions, itching dermatitis, erythema, sensations of dry skin, burning, amplification of skin pigmentation, garlic smell of exhaled air. In isolated cases, bronchospasm is possible. Some patients are poorly perceived the smell of the drug, which may be accompanied by nausea, urges on vomiting.

Contraindications

Increased sensitivity to dimethyl sulfoxide or other components of the drug, violation of liver and / or kidney functions, pronounced cardiovascular insufficiency, expressed atherosclerosis, angina, glaucoma, cataract, myocardial infarction, stroke, coma.

Pregnancy and lactation

the use of drug is contraindicated during pregnancy and lactation. For the treatment of drug breast-feeding Need to stop.

Children

do not use in children under 12 years old.

PeDODOSATION

It is possible to strengthen dose-dependent side effects. In these cases, the drug should be canceled, rinse the damaged place, the treatment is symptomatic.

Precautions

Do not apply the drug to damaged skin and skin with manifestations of allergies. Do not apply on the skin. It should be avoided by the dosage to the mucous membrane of the eye. When accidentally, rinsed with water immediately.

Caution is prescribed to patients with burded allerganemenesis, as well as persons suffering ischemic disease Hearts.

Given the possibility of individual intolerance to the medicinal product, it is recommended to carry out a drug sample tolerability. For this gel, a thin layer is applied to the skin of the elbow bend. The appearance of sharp redness and itching indicate increased sensitivity to Dimeksida. This patient should not be prescribed domexide-containing drugs. In the occurrence of allergic reactions to Domexide in the treatment process, the drug is canceled.

Impact on the ability to drive a car and working with mechanisms

Does not affect.

Interaction with other medicines

The drug is used with caution simultaneously with other drugs, since it is possible to enhance their specific activity and the strengthening of their toxicity. However, it is possible to use this drug in combination with heparin, antibiotics and NSAIDs. Increases absorption and increases the effect of other local medicines. Increases the hypersensitivity of microorganisms to aminoglycosides and beta-lactam antibiotics, chloramphenicol, rifampicin, griseofullvin. Enhances the effect and increases the absorption of ethanol, insulin. Sensitizes the body to the action of medicines for common and local anesthesia.