Novigan - instructions for use, analogs, testimonials and release forms (tablets) of the drug for the treatment of headache and toothache, during menstruation in adults, children and pregnancy. The composition of the anesthetic. Novigan: instructions for use Novigan indications
With headaches and migraines, you can take Novigan - it will quickly eliminate discomfort. Also, the medicine is useful for various colic and spasms, because it has a combined composition.
Description and action of the drug
Novigan refers to drugs with analgesic, anti-inflammatory action, is included in the group of combined NSAIDs. Producer - "Reddis Laboratories" (India), tablets in a pack of 10 pieces cost 140 rubles. The composition is represented by several active substances:
Tablets are white, round, convex, have a special embossing ("NOVIGAN"). The pills are film-coated. The composition also contains auxiliary components - starch, macrogol, sorbic acid and others. Novigan Neo is also on sale, it contains only 400 mg of ibuprofen.
Therapeutic effects of Novigan are antispasmodic, analgesic, anti-inflammatory.
The drug inhibits the production of prostaglandins due to the presence of ibuprofen, a propionic acid derivative. As the content of pain mediators decreases, thermoregulation normalizes (body temperature returns to normal), pain sensitivity is suppressed, and inflammation of tissues in the periphery is suppressed. Decreases with painful periods high level myometrial prostaglandins, minimizes pressure in the uterus, the frequency of contractions of the organ. All of these help reduce pain.
Myotropic antispasmodic pitofenone gives a direct myotropic effect, relaxes smooth muscle fibers internal organs. The m-anticholinergic fenpiverinium bromide works in a similar way through a central, peripheral effect. All components of the drug exhibit synergy, mutually reinforcing therapeutic effects.
Novigan indications and contraindications
The drug is used for pain syndrome of varying severity, mainly medium degree. Novigan perfectly copes with spasms of the vessels of the head, eliminating pain, a feeling of pressure, fullness, acute symptoms. It is also used for migraine pains.
The medicine can be used for any gynecological diseases as symptomatic remedy from pain, as well as in primary, secondary algomenorrhea.
Novigan is used to quickly eliminate pain in the joints, spine with osteochondrosis, arthrosis and other pathologies.
Among the indications for the use of Novigan tablets are also renal and biliary colic, intestinal spasms, which lead to painful sensations. The drug is used for violations of the motility of the gastrointestinal tract, biliary dyskinesia.
How many and what are the contraindications? Here is the main list of treatment prohibitions:
The drug is only allowed to be taken from the age of sixteen. It is forbidden during pregnancy, lactation. With caution drink pills for heart disease, metabolic disorders, Helicobacter pylori infection, history of gastrointestinal diseases. Novigan is taken only under the supervision of a doctor with simultaneous treatment with hormones, anticoagulants, antiplatelet agents.
Novigan's instructions
The medicine is taken orally, it should be washed down with water, without using juices, hot drinks. In people prone to irritation of the walls of the stomach, milk can be used to drink tablets. The drug is recommended to drink an hour before meals, or 2 hours after, but in case of violations of the gastrointestinal tract, this can be done immediately after eating. Recommendations for dosing regimen are as follows:
It is advisable to perform the minimum possible course of therapy, given the increased risk side effects as treatment progresses. It is strictly forbidden to exceed the specified amount of the drug per day. A longer course is possible only under the supervision of a specialist, taking into account regular blood tests and monitoring the function of the hepatobiliary system.
Side effects
Usually, a single dose of Novigan does not cause side effects; in the recommended doses in a short course, it is also well tolerated. But negative effects are still possible with an individual reaction of the body or the presence of various chronic pathologies. Most often, there are problems from the gastrointestinal tract - stomach pain, abdominal pain, appetite disorders, heartburn and diarrhea, constipation.
In severe cases, ulcers and erosions of the gastrointestinal tract were recorded, in complicated situations - perforation of ulcers, bleeding, acute pancreatitis.
The liver can respond to a course of therapy with the development of drug-induced hepatitis, the respiratory system - with bronchospasm, bouts of shortness of breath and exacerbation bronchial asthma. The following symptoms are also possible:
With intolerance to the components, there is a risk of headaches, migraines, dizziness, a number of people experience irritability, sleep problems, anxiety, nervousness. Hyperexcitability, confusion, hallucinations are occasionally noted, in especially severe cases - meningitis (the latter usually occurs in the presence of complex autoimmune pathologies). Also, during therapy, pressure, heart rate may change with the occurrence of arrhythmias.
There is a danger of kidney damage, the development of nephrotic syndrome, organ dysfunction. Hematopoietic organs can react with a decrease in hemoglobin, erythrocytes, platelets, leukopenia. Of the allergic reactions, skin reactions are most common, occasionally - erythema multiforme, bronchospasm, and systemic pathologies.
special instructions
With long-term use, you need to take tests to monitor the functioning of the kidneys and liver. The dose should be minimally effective - so the risk of negative effects is lower. If during therapy there are signs of pathology of the stomach or other digestive organs, it is important to conduct a complete examination to exclude peptic ulcer(including FGS). Research also includes:
For the period of therapy, it is forbidden to take alcohol, which increases the risk of developing a stomach ulcer. Due to possible side effects for the duration of treatment, it is necessary to abandon the management of transport, mechanisms. In case of an overdose, abdominal pain and vomiting, fainting, severe dizziness appear. Taking a large dose can cause coma and even death from severe forms of arrhythmia, respiratory arrest. Treatment is carried out only in the hospital!
Analogues and interaction
If you need to replace the drug due to intolerance or in the absence of Novigan in the pharmacy, there are a number of drugs that are similar in composition:
Tricyclic antidepressants increase the excretion of Novigan's metabolites, thereby increasing the risk of poisoning. Diuretics may reduce the effect of Novigan therapy. The drug enhances the effect of corticosteroids, and antacids reduce the concentration of ibuprofen in the blood.
Content
Everyone knows that it is dangerous to stop pain without finding out its origin, but there are situations when it is unbearable to endure. For such cases, Novigan is suitable - combination drug, analgesic-antispasmodic, which also has an anti-inflammatory effect. The drug is used to relieve migraine, pain in the joints and nerves, relieves spasms.
Instructions for use Novigan
The combined drug has an antispasmodic, analgesic, anti-inflammatory effect. It contains ibuprofen, which is a derivative of phenylpropionic acid. It has an antipyretic effect, suitable for the treatment of toothache and during menstruation. Pills render therapeutic effect a couple of hours after ingestion, a day later it is excreted in the urine. Manufacturer: India, Dr. Reddy's Laboratories Ltd.
Composition and form of release
The drug is in the form of biconvex film-coated tablets. NOVIGAN embossed on one side. Blister contains 10 pieces.
Pharmacodynamics and pharmacokinetics
The drug is complex tool, able to relieve inflammation, provide analgesic, antispasmodic effect. It suppresses the production of prostaglandins. Among the components are fenpiverinium bromide, which acts as an m-anticholinergic substance, pitofenone hydrochloride, which has a myotropic antispasmodic effect, ibuprofen, which is a non-steroidal anti-inflammatory drug.
Fenpiverinium bromide relaxes smooth muscles due to anticholinergic properties. Pitophenone hydrochloride has a myotropic effect on the muscles of internal organs, relaxing it, relieving spasms. Ibuprofen, which is a derivative of phenylpropionic acid, relieves fever, inflammation, inhibits the production of prostaglandins, which are responsible for thermoregulation, inflammatory processes, pain. The drug has an effect on the central nervous system, peripheral tissues.
In primary dysmenorrhea in women, the content of prostaglandins in the myometrium decreases, intrauterine pressure and heart rate decrease. Acting together, the components of the drug reinforce each other. They are easily absorbed by the intestines, reaching a maximum content in the blood after 1-2 hours. Almost all ibuprofen is bound to plasma proteins, processed by the liver, and excreted in the urine. The drug comes out with bile.
What are Novigan tablets for?
- pain caused by spasms of smooth muscles (biliary dyskinesia; renal, intestinal, biliary colic);
- migraine;
- spasms and pain in dysmenorrhea;
- pain in the lower back, joints, nerves: neuralgia, myalgia, sciatica.
Method of application and dosage
According to the instructions, without consulting a doctor, you can take pills for a course of no more than 5 days. For long-term use, it is necessary to supervise a doctor who will take regular readings. functional state peripheral blood and liver. Take - inside, one hour before meals or 3 hours after. You can take Novigan tablets immediately after a meal or drink them with milk to avoid irritating effects on the stomach. With spasms, take an analgesic 1 tablet 3 times a day.
special instructions
With long-term medication, it is recommended to monitor the condition of the kidneys, liver and peripheral blood composition. To reduce possible side effects and the effect of the drug on the gastrointestinal tract, a lower dose of the drug should be taken. At the first hint of gastropathy, a fecal analysis is required. A blood test for hematocrit and hemoglobin should also be done. If you need to take an analysis for 17-ketosteroids, you need to stop drinking the drug in two days. During the course of Novigan it is forbidden to drink alcohol, it is not recommended to drive a car.
Novigan during pregnancy
During pregnancy, the drug is prohibited for use in all trimesters, since Novigan threatens the normal development of the fetus. It is unacceptable to take painkillers during the period breastfeeding so that the components do not get into the milk.
Novigan children
You can not give medicine to children, adolescents under 16 years of age.
drug interaction
No adverse events were noted when using the analgesic with other drugs. When used in conjunction with inhibitors of microsomal oxidation, the risk of hepatotoxic effects is reduced. There is a decrease in the natriuretic effect of furosemide and hydrochlorothiazide, along with the hypotensive activity of vasodilators. The drug Novigan enhances the effect of fibrinolytics and the effect of indirect antiplatelet agents, anticoagulants, which can lead to the development of bleeding.
Antacids and cholestyramine impair the absorption of ibuprofen. The analgesic may increase possible side effects ethanol, estrogens, mineralocorticosteroids and corticosteroids, including in the latter case the likelihood of bleeding in the stomach, intestines. The hypoglycemic effect of sulfonylurea derivatives is increased, as are blood levels of digoxin, methotrexate, and lithium. The use of an antispasmodic analgesic with other non-steroidal anti-inflammatory drugs increases the risk of side effects.
Taking the drug enhances the effect of quinidine, m-anticholinergics, H1-histamine receptor blockers, butyrophenones and amantadine. The analgesic effect is enhanced when the drug is combined with caffeine. The use of the drug in conjunction with acetylsalicylic acid reduces the ability of the latter to relieve inflammation. With the use of myelotoxic drugs, hepatotoxicity increases.
The likelihood of hypoprothrombinemia increases if cefamandol, valproic acid, plikamycin, cefoperazone, cefotetan are used simultaneously with an analgesic. Cyclosporine and preparations containing gold may increase the effects of ibuprofen on the kidneys and lead to increased nephrotoxicity. Ibuprofen increases plasma levels of cyclosporine, making its hepatotoxic effect stronger. The concentration of ibuprofen in the blood increases with the use of drugs that block tubular secretion.
Novigan and alcohol
The use of the drug does not allow the adoption of even small doses alcoholic beverages. After drinking alcohol on the background of a course of taking pills, a violation is possible heart rate(tachycardia, bradycardia, acute heart failure).
Side effects
If the medicine is taken without exceeding the indicated dosage, side effects are not noted. If the following points occur during standard use of the drug, you should immediately contact a specialist. Possible side effects include:
- effects on the gastrointestinal tract (unpleasant, pain in the mouth, pancreatitis, ulcers on the mucous membranes of the gums and gastrointestinal tract, gastropathy, accompanied by abdominal pain, nausea, constipation, vomiting, diarrhea, heartburn, dry mouth);
- problems with the respiratory system: shortness of breath and bronchospasm;
- hepatitis;
- negative effects on the peripheral system and central nervous system (dizziness, anxiety or depression, clouding of consciousness, sleep problems or constant drowsiness, psychomotor agitation, aseptic meningitis may occur in people with autoimmune diseases);
- for of cardio-vascular system(high blood pressure, heart failure, palpitations);
- deterioration of vision and hearing, dryness in the eyes, swelling of the eyelids, the occurrence of noise or ringing in the ears;
- leukopenia, anemia, agranulocytosis, allergic nephritis, nephrotic syndrome, anuria, polyuria, kidney failure;
- allergic reactions(bronchospasm, rash, skin irritation, febrile attacks, urticaria, Quincke's edema, erythema multiforme exudative);
- decrease in glucose levels, changes in creatinine clearance, hematocrit and hemoglobin levels, increased or decreased sweating.
Overdose
If the dose of the analgesic is exceeded, it is necessary to consult a doctor, having the package of the drug with you. There is no antidote, but to cleanse the body, they do a gastric lavage, give an alkaline drink and activated charcoal. Overdose symptoms:
- nausea, vomiting, abdominal pain;
- drowsiness;
- lethargy;
- depression;
- noise in ears;
- metabolic acidosis;
- decline blood pressure;
- acute renal failure;
- atrial fibrillation;
- headache;
- respiratory arrest, coma.
Contraindications
Taking pills is unacceptable for a number of pathologies and physiological conditions of the body. It is dangerous to stop pain with a drug in the following cases:
- in the presence of inflammation in the intestines, including ulcerative colitis;
- data (in history) on an attack of rhinitis, bronchial obstruction, urticaria after taking a non-steroidal anti-inflammatory drug (NSAID), such as acetylsalicylic acid;
- erosion, ulcer duodenum, bleeding in the gastrointestinal tract;
- intestinal obstruction;
- liver and kidney disease, liver or kidney failure;
- hemophilia, problems with blood clotting (hypocoagulation);
- hemorrhagic diathesis;
- hematopoietic disorders;
- metabolic disorders (hyperkalemia);
- hyperplasia prostate;
- porphyria;
- tachyarrhythmia;
- angle-closure glaucoma;
- deficiency of glucose-b-phosphate dehydrogenase;
- granulocytopenia;
- diseases optic nerve;
- pregnancy and lactation, breastfeeding;
- after coronary artery bypass grafting;
- intolerance to the components of the drug (individual allergic reaction);
- childhood(up to 16 years old).
Terms of sale and storage
The medicine is sold in pharmacies without a prescription. Store in a dry and dark place, out of the reach of children, at a temperature not exceeding 25°C, no more than 5 years from the date of issue.
Analogues
By pharmacological properties Novospaz is close to Novigan. This combination drug has the same main active ingredients: ibuprofen, pitofenone and fenpiverinium bromide. An antispasmodic analgesic is used to treat pain and relieve spasms. Novigan's analogues for therapeutic effect:
- Nurofen. Sold in the form of tablets and gel for adults, syrup and suppositories for children. Main ingredient: ibuprofen. Relieves fever and inflammation, relieves pain.
- Brustan. Available form: tablets and syrup. Active ingredient: ibuprofen. Analgesic, has antipyretic and anti-inflammatory effect. Tablets are prohibited for children under 12 years of age.
- Ibufen. Available in the form of capsules (soft capsules are presented for children) and suspensions. Active ingredient: ibuprofen. The analgesic has antipyretic properties.
- Revalgin. Handicap release: tablets and solution for injection. Active ingredients: metamizole, pitofenone, fenpiverinium bromide. Action: analgesic and antispasmodic. Metamizole is excreted in the urine as metabolites.
- Pitophenone. Antispasmodic and analgesic, has an antipyretic effect. Form: tablets and injection solution.
- Maxigan. Handicap of release: tablets and ampoules. Active ingredients: metamizole, pitofenone, fenpiverinium bromide. Action: antispasmodic, analgesic, relieves inflammation. Tablets are prohibited for children under 5 years of age.
Novigan price
You can buy tablets without a prescription at any pharmacy in Moscow and other Russian cities, their cost depends on the number of pieces in the package. Average price: from 80 to 180 rubles.
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We will describe such a complex drug as Novigan, its instructions for use and tell you what it helps from. After all, there are often situations when painful sensations of various origins should be stopped. But not all pills that are available in a pharmacy should be taken thoughtlessly.
Only after reading the instructions, and even better, after consulting with a doctor, you can use painkillers. Some people experience side effects, and in some situations it is completely contraindicated to take most drugs, even those sold in pharmacies without a prescription. Individual characteristics of the body, allergic predisposition and chronic diseases significantly affect the availability of medicines in your home first aid kit.
Composition and form of release
The drug Novigan contains a complex of active substances. This:
- Ibuprofen, which has anti-inflammatory, analgesic and antipyretic effects, in the amount of 400 mg;
- Pitophenone hydrochloride, which acts on the smooth muscles of all organs, eliminating its spasms, 5 mg each;
- Fenpiverinium bromide, which additionally provides a relaxing and calming effect, in a volume of 100 mcg.
Due to these components, Novigan acts simultaneously as an anesthetic in many situations, an antispasmodic, and is also able to reduce high temperature during inflammatory processes in organism.
It inhibits the synthesis of prostaglandins and blocks pain signals entering the central nervous system. And in combination, all these components can quickly help a person feel better and eliminate the unpleasant symptoms of the disease.
Novigan is available in the form of film-coated tablets. One blister contains 10 pieces.
Indications and contraindications
Doctors prescribe this drug in all cases when it can affect a painful syndrome and if it is necessary to normalize body temperature. What Novigan helps with:
- Headaches and migraines.
- Gynecological problems, especially cases of dysmenorrhea and menstrual syndrome.
- Myalgia, neuralgia, sciatica, as well as in the treatment of other neurological disorders.
- Eliminates discomfort in the joints.
- Toothache of various origins.
- With intestinal, gastric, liver diseases, biliary dyskinesia and other problems, when pain occurs due to spasms of smooth muscles.
The duration of taking the drug should not exceed five days and be sure to follow the dosage indicated by the doctor. And in some cases, it is completely forbidden to use this tool, as it can cause various negative consequences. Contraindications are:
- cases of intestinal obstruction, diseases of the gastrointestinal tract, especially in an acute state, with internal bleeding, ulcers, gastritis and other damage to the mucous membrane of the stomach, duodenum, etc .;
- special care should be taken when taking the drug if there are violations of the liver or kidneys;
- diseases of the heart, blood, blood vessels, this complex of substances is able to increase or decrease blood pressure and disrupt the processes of hematopoiesis;
- with glaucoma and diseases of the optic nerve;
- prostatic hyperplasia;
- in old age;
- in cases of diabetes;
- if any allergic reactions to anti-inflammatory drugs have previously been observed nonsteroidal drugs in the form of urticaria, bronchial asthma, polyps of the nasal mucosa, rhinosinusitis, etc.
- during pregnancy and while breastfeeding;
- simultaneously with alcohol or even when smoking;
- after long-term use of other non-steroidal anti-inflammatory drugs or drugs such as anticoagulants, SSRIs, antiplatelet agents, oral corticosteroids, etc.
Instructions for use Novigan
According to the main recommendation, these tablets are drunk one hour before meals or 2-3 hours after. But, if this causes irritation of the gastric mucosa, then it is permissible to use them immediately after a meal, or at least drink a glass of milk. Most often prescribed three times a day, one tablet. In some cases, doctors prescribe two or three times a day, then the maximum daily dose should not exceed six pieces.
They should be taken no longer than five days. In cases where long-term treatment is required, you should constantly be monitored by a doctor and monitor the condition of the liver, kidneys and blood with the help of tests.
How long does it take for the remedy to work? Depending on individual characteristics and sensitivity to the components of the drug, Novigan can eliminate pain symptoms within 15-20 minutes after ingestion. But sometimes it takes up to an hour.
Side effects
With proper use of Novigan and taking it at the recommended doses, adverse reactions occur extremely rarely. Nevertheless, you need to be aware of the possibility of their occurrence. So, after using the drug or its overdose, the following reactions of the organism may occur:
- exacerbate hepatitis;
- shortness of breath or bronchospasm will appear;
- aphthous stomatitis, gastropathy, ulcers of the gastric or intestinal mucosa, pancreatitis and other problems with the gastrointestinal tract;
- attacks of tachycardia, high blood pressure or cases of heart failure;
- the occurrence of migraines and headaches, the appearance of nervousness, dizziness, irritability, insomnia and other mental disorders;
- exacerbation of renal and hepatic diseases;
- anemia, thrombocytopenia, agranulocytosis or even thrombocytopenic purpura;
- problems with hearing, vision, ringing in the ears, paresis of accommodation;
- allergic reactions of a very different nature.
At the first negative manifestations, you should stop taking the remedy and consult a doctor for help. V acute cases overdose or allergies, you need to call an ambulance.
Price
The cost of the drug in pharmacies in Moscow ranges from 80-110 rubles per pack of 10 tablets. In Kiev, Novigan will cost 150 hryvnias for the same amount of medication.
To know exactly how much this remedy costs, you need to check with the pharmacies of your city, since these prices are approximate.
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