Reflux esophagitis is an inflammation of the esophageal mucosa due to the back reflux of the contents of the stomach and duodenum into it. The appointment of adequate treatment is important to prevent dangerous complications.

The symptoms associated with reflux cause severe discomfort to the patient and markedly impair quality of life. With reflux, there is not only heartburn, pain, but also the risk of developing adenocarcinoma of the esophagus.

Signs of reflux esophagitis

Gastric juice has a low pH value, which indicates its acid reaction. Its entry into the alkaline environment of the esophagus causes symptoms of pain and discomfort in the xiphoid process or epigastrium.

Reflux disease is manifested by frequently recurring symptoms:

• Heartburn after eating, especially after taking fatty or hot foods, coffee and alcoholic drinks.
• Sour eructation or belching of air, feeling of nausea.
• Lump in throat, difficulty swallowing.
• Pain behind the sternum after eating.

Symptoms of this disease are markedly increased when a person lies down after eating.

Principles of treatment

The causes of reflux and its treatment are inextricably linked, and therapy should be comprehensive:

• First of all, normalize the mode of motor activity, nutrition. It is necessary to eat fractionally and in small volumes.
• The next component of therapy is the use of medications that reduce the severity of symptoms. Their reception is carried out situationally. For example, for heartburn, patients are prescribed tablets and suspensions with an antacid effect (Phosphalugel, Almagel, Maalox, etc.).
• There are drugs used for basic treatment. Reflux esophagitis requires the appointment of antisecretory drugs (omeprazole, pantoprazole, etc.). Gastroenterologists recommend taking prokinetics (Cerukal, Domperidone).
• The doctor with esophagitis due to reflux should also try to treat the associated imbalance of the intestinal microflora. For this, probiotics and eubiotics are used, such as Hilak forte.

These medications should not be taken for more than two weeks. During the day, these drugs are taken often: up to 3-4 times. This is due to the fact that healing effect after taking the drug lasts no more than 4-6 hours.

For pain

With severe pain, Almagel A should be taken with an anesthetic effect. This tool has a more pronounced effect than just Almagel.

Medications for pain relief and healing of the mucosa with erosions: Drotaverine, Solcoseryl, sea ​​buckthorn oil, Actovegin, pantothenic acid.

Sorbents

In the medical treatment of reflux esophagitis, it is necessary to use adsorbents. This group of drugs has a therapeutic effect by binding bile acids and other aggressive components of gastric or duodenal contents.

In addition, these drugs reduce the severity clinical manifestations esophageal reflux by forming a kind of film. These medicines should be taken according to the situation, but not longer than a week.

For nausea

With severe nausea and the urge to vomit, Cerucal injections can be given to the patient. An injection with this compound depresses the center of vomiting and eliminates unpleasant symptoms. The dose of the drug is the average therapeutic dose, according to the instructions for the drug.

Basic treatment, main course

After the symptoms of damage to the esophagus subside, doctors prescribe the main therapy. It includes the use of antisecretory drugs. These drugs are effectively used for long-term treatment of pathology.

Reflux esophagitis can occur in two ways.

1. With the formation of erosion.
2. No mucosal defects.

Regardless of the form, reflux esophagitis should be treated with antisecretory agents. They are aimed at reducing acid formation in the stomach. The aggressive factor becomes weaker, the symptoms are eliminated, conditions are created for the healing of the mucous membrane of the organ in the presence of erosive defects.

Let's talk about the drugs that are most often used to treat esophagitis. The first line is proton pump inhibitors. These include:

• Rabeprazole;
• Lansoprazole;
• pantoprazole;

Any of these drugs is effective and efficient in the fight against acid aggression.

To cure the erosive variant, it is necessary to take proton pump inhibitors at least twice a day. The dosage must be adequate. It depends on the presence / absence of erosion. For instance:

• Omeprazole should be taken twice a day (morning, evening) at 20 mg.
• Lansoprazole is prescribed at 30 mg, taken twice a day.

The dosage and frequency of administration is chosen only by the doctor, depending on the situation!

A form of reflux esophagitis without the formation of mucosal defects requires the following use of drugs:

1. The course of treatment takes place within a month.
2. Proton pump inhibitors are taken once a day.
3. The dosage of other drugs can be from 10 mg to 40 mg. The amount depends on the characteristics of the inflammatory process and is chosen by the doctor.

When asked if it is possible to replace medicines this group of histamine blockers, only the attending physician can answer, who will take into account the indications and contraindications.

Typical treatment regimens

1. Therapy with one drug. Such a scheme is far from the most effective, because individual symptoms are not taken into account.
2. dynamic therapy. Different drugs are prescribed depending on the intensity of the inflammatory process. Treatment involves a strict diet and taking antacids. If there is no effect, stronger drugs are prescribed, similar in principle of action.
3. The third regimen involves taking strong proton pump blockers. When severe symptoms go away, weak prokinetics are taken.

Folk methods and homeopathy

These two concepts should not be confused. Homeopathy - complex therapeutic effects based on the fact that like cures like. That is, when using drugs that cause the same changes that are observed in the disease, it is likely to be cured or significantly alleviate the condition and symptoms. The homeopathic approach is not supported by all doctors, as there is a danger of causing serious complications.

Folk methods are based on the principles traditional medicine, but plants, their parts are used. For instance:

• Celery root. Juice drink on an empty stomach for 1 tbsp. spoon 30 minutes before meals.
• Collection of herbs: chamomile flowers (1 teaspoon), bitter wormwood (2 teaspoons), mint (2 teaspoons). Pour this mixture into 1 liter of boiling water. Then let stand for two hours. The healing infusion is filtered. Take 1/2 cup 30 minutes before meals.

Dill seeds. Take 2 teaspoons of seeds and grind. Brew with one glass of boiling water. Let it brew for 2-3 hours, filter. Take 1 tbsp. spoon 4 times a day.

Basically, the application is found by means that reduce acid formation in the stomach.

Reflux esophagitis is a condition in which stomach contents back up into the esophagus. The disease is quite common, according to research, every second inhabitant of European countries has a similar problem. Despite the prevalence of such a disease, for reflux esophagitis treatment, drugs are selected strictly individually, taking into account the degree of damage, symptoms and symptoms. physiological characteristics the patient's body.

Diseases in adults are manifested by a mass of unpleasant sensations:

• belching;
• nausea;
• vomiting;
• pain in the peritoneum and heart;
• heartburn and other symptoms;
• caries and destruction of tooth enamel;
• coughing and feeling short of breath.

Also, during the progression of the pathology, the patient may have problems with the function of swallowing. A similar condition is noted during the transition of the disease to a more severe stage with the formation of cicatricial narrowing of the esophageal passage.

General principles of treatment

For the treatment of reflux esophagitis should be used complex therapy, represented by drugs, diet and prevention. General recommendations in the pathology of the esophagus the following:

1. Use moderate physical activity, which has a positive effect on the entire body and is considered an additional measure in the treatment of various diseases. However, with the diagnosis of reflux esophagitis, there are some prohibitions. It is not allowed to perform strength exercises or movements with forward bends.
2. Balanced diet. Diet is the main event in the treatment of ailments from the side digestive system and also for the prevention of exacerbations of chronic diseases.

Medicines for the treatment of this pathology can be divided into two categories: some fight directly with the cause that caused the onset of the disease. And other remedies help relieve symptoms. Reflux esophagitis is treated with medicines that help reduce the acidity of gastric juice, as well as protect the digestive organs. These include:

• proton pump inhibitors;
• antacids;
• alginates;
• H2 blockers of histamine.

Histamine component inhibitors

A feature of the treatment of the esophagus with drugs is that they help to normalize the activity of the glands located in the stomach, as well as the mucous layer of all organs of the digestive system. When choosing funds, those that act as protection for the mucous membrane of the esophagus, stomach and intestines are also selected. These drugs have a high ability to heal defects and flaws on the mucous membrane of the affected organs.

Drug therapy involves a long course of taking them. If the patient has severe manifestations of this pathology, patients are prescribed double doses. After normalization of the condition, patients continue to take drugs in the required maintenance dosages. Known representatives of this group are: Esomeprazole and Ranitidine.

Antacids

This type of drug has an operational and effective effect on reflux esophagitis. Antacids work within minutes of taking them. Medications help reduce of hydrochloric acid. Namely, unpleasant symptoms are associated with this component of gastric juice, in particular, burning behind the sternum and pain in the area chest. The representatives of this group include the following means:

• Rennie;
• Almagel;
• Maalox.

Antacids - strong drugs which are allowed to be used no more than 2 weeks.

Alginate preparations

The advantages of these drugs include the following characteristics:

• neutralization of hydrochloric acid, which helps to reduce the frequency of emissions into the lumen of the esophagus of gastric contents;
• the formation of a protective layer on the mucous membrane of the organ;
• restorative function of the digestive system;
• the safety of drugs, which makes it possible to use these drugs even during the period of bearing a baby and during lactation.

Prokinetic drugs

The advantage of prokinetics is quite extensive. The drugs are widely used for the treatment of the esophagus in adults due to their unique features:

• improves motility of the stomach and intestines;
• hydrochloric acid has less contact with the esophagus;
• the functioning of the esophageal sphincter is normalized, even if the patient uses small dosages of prokinetics.

The last point is important, because it is because of the weakness of the lower esophageal sphincter that heartburn is provoked. When the process becomes pathological, it becomes the reason for the constant throwing of gastric contents through the esophageal lumen.

With the appearance of a feeling of heaviness after a meal in adults, prokinetics are prescribed. One of the representatives of this class is Motilium. It is an antiemetic drug that reduces clinical picture pathology. The medicine is sold in the form of tablets and suspensions. Motilium in the body performs the following tasks:

• the activity of the center, which is responsible for the gag reflex, is suppressed in the brain;
• pressure increases in the passage of the esophagus;
• the agent activates the promotion of the food bolus from the stomach.

However, despite the many positive properties, this medicine has its negative points:

• unpleasant signs of digestion: thirst, diarrhea, constipation;
• drowsiness, speech weakness, headaches, seizures;
• violation of the menstrual cycle;
• skin rashes and itching.

It is necessary to use the remedy only as prescribed by the doctor, who determines the course and dose.

Symptomatic remedies

When the provoking factor in the appearance of these symptoms becomes nervousness and severe stress therapy also includes consultation with a psychiatrist and psychologist. In addition, the patient is prescribed sedatives.

If the nature of the inflammation is associated with a bacterial lesion, then a course of antibacterial medicines will be required. Therapy, among other things, also includes the use of immunostimulants that increase the body's defense mechanism.

In the treatment of chronic esophagitis, which is provoked by the bacterium Helicobacter pylori, doctors often use De-Nol. The advantages of this tool include:

• an increase in the production of mucus and bicarbonates, the agent activates the processes for the formation of new tissues in the affected areas;
• blocking substances that have a destructive effect on the mucous membrane;
• normalizes the movement of blood through the capillaries, helping to strengthen their blood supply.

It is not allowed to abuse the intake of painkillers, so as not to aggravate the situation. With the constant use of analgesics, a sharp refusal to take them can provoke a deterioration in the patient's condition. For this reason, the specialist prescribes a phase-out scheme for these substances. In the diagnosis of esophagitis can not be used nutritional supplements with iron.

Prevention

The best preventive measures for any disease, including reflux esophagitis, are measures to maintain healthy lifestyle life:

• avoidance of stress;
• correct diet;
• a ban on resting lying down after a meal;
• moderate consumption of alcoholic beverages;
• to give up smoking;
• compliance proper nutrition: a ban on spicy and sour dishes, any smoked meats.

Conclusion

Treatment of this disease should be carried out comprehensively. There is no need to self-medicate, only an experienced doctor will be able to choose the right course of treatment based on diagnostic data and symptoms. Positive results can only be achieved if all doctor's prescriptions are followed.

With reflux esophagitis, the tissues of the lower esophagus are damaged by acidic contents thrown from the stomach. This is what explains the unpleasant sensations that disturb a person - discomfort, belching sour, coughing. Similar symptoms inherent in reflux can provoke a variety of reasons. Therefore, only a specialist should prescribe the optimal treatment tactics - which medications, their doses, duration of administration. Self-medication is unacceptable.

Conducted medical studies have convincingly shown that in order to cope with reflux esophagitis, treatment with drugs should be combined with other measures - diet therapy, correction of the patient's lifestyle. Only to eliminate the true causes of the disease, you can achieve your goal - to prevent the recurrence of the disease, to eliminate discomfort.

Principles of treatment of reflux esophagitis:

• lowering the acidity of the contents of the stomach to acceptable parameters by prescribing appropriate medications;
• optimal stimulation of the motility of the structures of the digestive tract - strengthening their evacuation activity;
• restoration and protection of the mucous membrane of the esophageal tube with drugs.

The causes and treatment of the disease are closely interconnected - by eliminating the first by the influence of the second, the patient improves his own well-being. However, it is not recommended to independently purchase in the pharmacy network and take this or that remedy for reflux disorders. Without knowing the mechanism of pathology formation and the point of application pharmacological action drug, you can achieve the opposite result - the appearance of severe complications.

Stages of treatment

The treatment regimen for reflux disease involves taking medication in 2 stages:

1. healing of existing mucosal defects, relief of inflammatory processes;
2. restoration of the full activity of the esophageal tube and its natural sphincters.

The first stage requires taking drugs from the anti-inflammatory and anti-ulcer subgroups for at least 6-8 weeks. The duration of pharmacotherapy directly depends on the severity of symptoms and the degree of tissue damage.

At the second stage, the patient takes maintenance doses of medications in order to prevent possible relapse and maximize the restoration of the health of the organ. In severe cases, a person may require lifelong maintenance therapy.

To date, experts have developed several schemes drug treatment reflux esophagitis, which includes drugs with different mechanisms of action and the duration of the desired effect.

Antacids and alginates

The purpose of the use of representatives of this subgroup of pharmaceuticals is the rapid neutralization of hydrochloric acid in the stomach area. In addition, against the background of their use, more bicarbonates are produced, natural defenders of the mucous membrane of digestive structures. They also bind bile pigments and inactivate pepsin.

In most cases, specialists give preference to non-systemic medicines, which contain aluminum or magnesium. Modern antacids:

• Almagel
• Phosphaluge
• Maalox

It is optimal to take them in liquid form, which allows them to be qualitatively distributed over the entire surface of the mucosa.

Antacids are designed specifically to reduce the acidity of gastric contents. The list of contraindications to them is minimal, for example, individual intolerance to active or auxiliary components.

proton pump inhibitors

For the production of hydrochloric acid, special cells of the digestive tract are responsible. To reduce their hyperactivity, which is the main cause of the sour belching symptom, it is necessary to take drugs from the subgroup of proton pump inhibitors.

Representatives of this subgroup, for example, Omez, Rabeprazole, Pantoprazole, have the following pharmacological effects:

• a significant decrease in the level of basal, as well as stimulated emission of hydrochloric acid;
• restoration of the physiological activity of the cells of the gastric mucosa and esophageal tube.

To the undoubted advantages of these drugs, including Omez, experts point out:

1. rapid onset of the desired effect;
2. not absorbed into the systemic circulation;
3. the minimum list of side effects on the patient's body.

Features of the structure of the drug Omez allow you to use it for a long time at the second stage of pharmacotherapy. Symptoms of bitterness in the mouth and discomfort in the epigastric region, characteristic of gastric reflux, due to this, appear much less often.

H2-histamine receptor blockers

Effective drugs for esophagitis, which have already managed to prove themselves with the best side both specialists and patients - blockers of H2-histamine receptors. Prominent representatives of the subgroup are Ranitidine, Famotidine, Cimetidine, Roxatidine.

Their use has the same goal as proton pump blockers - to effectively reduce the concentration of acid in the digestive juice. They directly affect H2-histamine receptors, prevent their vigorous activity, due to which the production of hydrochloric acid is significantly reduced.

The most effective representatives of this subgroup of medicines are Famotidine and Roxatidine. With their use, there is less likelihood of a withdrawal syndrome.

The undoubted advantages of drugs include:

• a rapid decrease in the production of hydrochloric acid in the stomach;
• a significant slowdown in the secretion of pepsins;
• the possibility of using minimal doses to achieve a therapeutic effect;
• stimulation of the own defenses of the gastric mucosa;
• improvement of local blood supply to tissues and acceleration of their epithelialization.

With esophagitis in adults, H2-histamine receptor blockers are used quite often. However, the optimal dose and duration of administration should be prescribed only by the attending physician.

Subgroup of prokinetics

Tablets for reflux, the main purpose of which is to enhance antropyloric motor function, are representatives of the subgroup of prokinetics. Due to the acceleration of the evacuation of the esophageal bolus from the stomach, there is a weakening of the reflux into the esophageal tube. There is also a pronounced stimulation of the tone of the lower cardia - a muscle ring that normally blocks the entrance to the stomach. The initiation of esophageal self-cleaning is also formed.

Reflux can be cured by:

1. Cerucal, Raglan - have the ability to enhance the motility and tone of the structures of the gastrointestinal tract, as well as sphincters
2. Motilium, Domperidone - the absence of systemic effects is indicated as an advantage
3. Ganaton - newest generation prokinetics, helps to accelerate the epithelization of erosions, is effective even with severe inflammation.

How to take prokinetics, their doses and duration of pharmacotherapy should be determined only by a specialist. With a mild course of the disease, it is quite possible to completely cure it.

Subgroup of gastroprotectors

Effective drugs for the treatment of reflux, of course, are gastroprotectors. Thanks to the timely application, they have a beneficial effect on the tissues of the esophageal tube, as they are able to increase the protective functions of the digestive mucus.

Symptoms of the disease disappear much faster if complex pharmacotherapy contains:

• Cytotec
• Cytotec
• Venter
• Ursofalk
• Sucralfate

Symptomatic therapy

Sometimes the aggravation of the disease occurs due to nervous shocks, psycho-emotional overload. In this case, it is not possible to cope with the problem only with the help of the above medicines. To treat reflux is required specialized assistance psychotherapist.

If the symptoms of reflux of the food bolus are combined with spastic impulses, it is enough to take an antispasmodic, for example, Duspatalin. After elimination of the hyperspasm of the smooth muscles of the intestinal loops, relief of well-being occurs.

If a person prefers homeopathy, it should be noted that with its help it is possible to cope only with initial stage illness. At severe course reflux, multicomponent pharmacotherapy is mandatory.

One of the common pathologies of the upper digestive system is reflux esophagitis. This disease causes quite unpleasant symptoms that cause discomfort to patients and worsen the quality of life. Most effective methods Treatment of reflux esophagitis should be used without fail, as the disease can cause dangerous complications.

What is this disease

Reflux esophagitis is a pathology characterized by abnormal contraction of the smooth muscles of the intestine, which leads to the reflux of gastric contents into the lumen of the esophagus. Since the environment of the stomach is quite aggressive, it adversely affects the tissues of the esophagus, which leads to the development of an inflammatory process.

The mechanism of occurrence of this pathology is not fully understood. Medical scientists identify several main factors that increase the risk of developing such an ailment. These include:

• Violation of the motility of the gastrointestinal tract. Under normal conditions, the muscular contractions of the digestive tract ensure the movement of food from the stomach to the anus. In patients with reflux esophagitis, abnormal peristalsis is noted, which leads to gastroesophageal reflux.
• Insufficiency of the cardiac sphincter of the stomach. This anatomical unit is extremely important for human body. Sphincters located in the stomach between the esophagus and duodenum eliminates the risk of backward movement of digested food. With insufficient strength of contractions of the sphincter muscles, casting can occur even in patients with normal peristalsis.

In addition, there is also a hereditary factor. In many patients, relatives suffered from the same ailment. Perhaps it is by inheritance that such features of the functioning of the digestive system are transmitted. Treatment of reflux should be directed to the cause of its occurrence.

Symptoms

The main ones are:

• Heartburn. The ingress of an acidic environment into the lumen of the esophagus is always accompanied by the appearance of heartburn. With this disease, it will appear 15-20 minutes after eating. In almost all clinical cases of reflux esophagitis, it is associated with food intake, unlike other diseases in which it occurs at any time.

• Pain behind the sternum. The ingress of a large amount of acid into the esophagus leads to the development of inflammation, which is accompanied by pain. At the same time, during the diagnosis, it is necessary to differentiate with heart diseases, since they are also accompanied by pain of a similar nature and the same localization.
• Dyspeptic disorders. A characteristic feature that helps to make a correct diagnosis are digestive disorders. Patients develop sour belching, which indicates a violation of the pH of the esophagus. In addition, nausea and vomiting may occur, which is a sign of irritation of the lower esophagus.

This disease is equally common in both men and women. Most often, it is diagnosed at a young age, which requires adequate treatment that will prevent the development of complications such as esophageal cancer or Mallory-Weiss syndrome.

Treatment

In order to designate the most effective treatment reflux esophagitis, you need to undergo a comprehensive examination, which must necessarily include gastroscopy. It is this examination that makes it possible to determine the immediate cause of the onset of the disease, as well as to assess the degree of damage to the mucous membrane of the esophagus.

The regimen for the treatment of reflux esophagitis consists of a combination of the following groups of drugs:

• . Representatives of this group of drugs are the most effective symptomatic therapy that helps eliminate the appearance of heartburn. Antacids reduce the concentration of hydrochloric acid in the stomach, which prevents unnecessary injury to the mucous membrane of the esophagus. Taking antacids is allowed only on prescription, as they have a number of side effects and contraindications. The most affordable drug is Maalox. A feature of the drug Maalox is that it can be used to treat pregnant women and children.

• . The course of drug treatment of reflux esophagitis should include prokinetics. These drugs help to normalize the contraction of the muscles of the digestive tract, which ensures the normal movement of food. One of the most common drugs in this group is Motilium.
• . The use of such drugs for esophagitis reduces the amount of hydrochloric acid produced, which prevents the pH from shifting to the strongly acidic side. Most often, patients are prescribed Omez. Main active substance, which is part of the drug Omez, is Omeprazole. The main difference between Omez is that it also has prokinetic properties.

In some cases, the use of drugs for esophagitis is not enough. This is observed in cases where structural changes occur in the cardiac valve of the stomach.

In this situation, patients are shown surgical treatment, which can be performed using a gastroscope or openly through a laparotomy access.

Such treatment of esophagitis is based on suturing the sphincter lumen, which almost completely eliminates repeated refluxes.

Prevention

Like any disease, reflux is easier to prevent than to cure.

In order not to treat reflux, it is enough to follow a number of rules, among which are:

• Eating small meals. Eating a large amount of food at one time leads to stretching of the muscle layer. Because of this, there may be violations of the contractile function of the stomach, which will lead to the occurrence of this kind of disease.
• Exclusion from the diet of excessive amounts of spicy and sour foods. Such products lead to the fact that the acidity of the stomach increases. With reflux esophagitis, this plays a big role, since low pH can cause damage to the walls of the esophagus.

In addition, an important place is occupied by the quality composition of food. Excessive amounts of fats and proteins stimulate the production of gastric juice, which can cause not only reflux esophagitis, but also other stomach diseases, such as gastritis and peptic ulcer.

If the patient has esophagitis, treatment should be carried out exclusively according to the scheme prescribed by the doctor. Due to the use of drugs for the treatment of reflux, dangerous complications can be avoided.

Reflux esophagitis is a disease that requires mandatory complex drug treatment, which includes lifestyle correction, maintenance therapeutic diet, the use of medicines and preparations prepared according to folk recipes. In severe cases of the disease, surgery is prescribed. When prescribing treatment for reflux esophagitis, the gastroenterologist chooses the drugs, relying on data on the causes and symptoms of the disease.

The duration of treatment for reflux esophagitis depends on its form. The non-erosive form therapy lasts 4 weeks. What medications to prescribe and in what dosage - the specialist decides depending on the stage of the disease. In addition to drug therapy, it is possible to take decoctions and infusions of herbs, diet therapy. With an erosive form, treatment increases to 8 weeks and includes the use of hydrochloric acid blockers, healing and hemostatic (if necessary) substances.

In case of complications, concomitant diseases or advanced age, the patient undergoes therapy for up to 12 weeks. With successful completion of treatment, prophylactic use of drugs is recommended in order to achieve remission within six months.

Treatment regimens

1. One drug is prescribed, not taking into account the symptoms and complexity of the disease. Such a scheme is not useful and in most cases has no effect.
2. The second way involves following a specific diet and taking antacids. Depending on the stage of the course of inflammation, substances of different effectiveness are prescribed.
3. The third method is based on the initial relief of symptoms by taking proton pump blockers. The second line is taking prokinetic drugs.

The classical scheme consists of four stages, depending on the stage of tissue damage:

• In the first degree, with mild symptoms, it is recommended to take prokinetic drugs and antacids.
• The second degree requires maintaining a balance healthy eating and includes the use of acid blockers.
• With pronounced inflammatory process prescribe proton pump inhibitors, H-2 blockers and prokinetics.
• The fourth degree is not treated with medication and requires surgical intervention.

Medicines used to treat

Therapy of inflammation of the esophagus takes place with the use of several groups of drugs. At various stages of the disease, the use of drugs is carried out in a complex manner in different combinations and dosages.

Prokinetics

The active substance affects the muscular activity of the digestive organs, normalizes the tone of the esophageal sphincter. Restoring the normal functioning of the esophagus contributes to the rapid promotion of food, helps to cleanse the mucosa. This group includes Itopride, Domperidone, Motilium. The latter is prescribed in the presence of vomiting and a feeling of nausea. Ganaton helps relieve symptoms in a week, heal in three weeks and has no side effects.

proton pump inhibitors

Drugs that help reduce the production of hydrochloric acid by mucosal cells. Used to relieve severe symptoms of inflammation and relieve pain syndrome. Fast-acting substances with minimal side effects.

The course of therapy is prescribed by a specialist, since prolonged use can lead to bone fragility and affect kidney function. The main drugs included in the group: Omeprazole, Lansoprazole, Pantoprazole.

H-2 blockers

They have a similar effect with PPIs, the action occurs due to the blocking of histamine receptors. The production of hydrochloric acid is suspended, which makes it possible to alleviate the condition of the esophagus and stomach.

The fifth generation of such medicines has been developed. The most effective are Ranitidine and Famotidine. Abrupt cessation of use can lead to a short-term increase in the symptoms of the disease.

Alginates and antacids

With esophagitis, drugs that neutralize the effect of acid on the esophagus are prescribed for a successful cure. Antacids are recommended to drink in liquid form. The duration of the drug is 10-15 minutes. The course of therapy is a maximum of two weeks, since the composition of the funds includes magnesium and aluminum. This group includes Phosphalugel, Almagel, Maalox.

Alginates have a milder effect, so they are prescribed during pregnancy. The composition includes alginic acid, which, after ingestion, forms a protective layer on the surface of the mucosa.

Cytoprotectors

Increase the degree of protection of the mucous layer of the esophagus and stomach with. Tablets help improve blood flow, increase the secretion of protective mucus, lower the level of acidity, while promoting the healing of foci of erosion. The most famous drugs are Misoprostol and Dalargin.

Use of antibiotics for esophagitis

With the phlegmous type of esophagitis, antibiotics are prescribed to relieve inflammation in adult patients and relieve pain. With prolonged therapy, it can develop, therefore, the combined use of antifungal agents is recommended.

Use of other drugs

Ursosan reduces the possibility of tissue damage by gastric juice due to the destruction and removal of bile acids. Trimedat helps reduce reflux and increases the speed of food passing through the esophagus.

Symptomatic therapy

If reflux developed against the background of another disease or pathology appeared as a complication of esophagitis, symptomatic treatment is carried out:

• With neurological and psychological problems you need to consult a doctor of the desired profile. Sedatives, etc. may be prescribed.
• At peptic ulcer stomach antibiotics are prescribed. Denol helps to neutralize the action of Helicobacter pylori, improves blood circulation in the walls of the stomach, and alleviates the unpleasant symptoms of the disease.
• With a decrease in immunity, immunomodulators are prescribed.

Therapy also includes vitamin complexes With high content macronutrients to improve general condition organism.

Treatment approaches

Depending on the stage of tissue damage, the presence of complications, etc., a suitable treatment method is chosen.

The first includes taking medications for esophagitis of different activity in several stages:

1. Maintenance of a therapeutic diet and the use of antacids.
2. Use of H-2 blockers or prokinetic drugs.
3. Comprehensive intake of PPIs and prokinetics.

The second technique is carried out in three approaches:

1. It is prescribed to relieve symptoms.
2. Taking inhibitors for five days to relieve discomfort.
3. The use of tablets only with an exacerbation of the disease.

The third technique is:

1. For mild inflammation, a short course of antacids or acid blockers and adherence to diet and diet.
2. For stage II treatment, a long course of PPIs or acid blockers and prokinetics. Diet therapy is also shown.
3. Stage III requires the use of a complex of blockers and PPIs or prokinetics. Instructions for use shows the maximum allowed doses.
4. If previous appointments have not brought effect, surgical intervention is necessary.

Supportive care

Medical treatment of esophagitis is the most effective. After undergoing therapy, it is necessary to adhere to a certain lifestyle and conduct a six-month course of maintenance treatment for reflux.

Use of maintenance therapy, diet, change in regimen and some habits, use of drugs traditional medicine will help to avoid relapse and in the future the disease will not cause inconvenience.