Everything medications It can be used exclusively to appoint a doctor. Only so you can not only cure, but also keep your health. In this article, I want to tell about such a drug as "Novigan": indications for use.

Scope of the drug

Initially, I must say that it is spasmodaging. That is, the drug is able to provide an integrated effect:

• anti-inflammatory;
• analgizing;
• spasmolytic.

So, the drug tool "Novigan" consists of their following essential elements: ibuprofen, which has an antipyretic, analgizing and anti-inflammatory property; Pitophenone hydrochloride, which relaxes musculature internal organs, removing spasm; Fenpiverine Bromide, which, as in the previous case, has an antispasmodic effect.

It is important to note that it is the combination of these three elements that leads to the fact that the drug itself has a powerful effect on the body. After all, these elements enhance each other's action, the maximum accelerates the achievement of the desired result.

Preparation "Novigan": Indications for use

When the doctor can assign an application this drug?

1. Pains that are accompanied by spasms: with renal and intestinal colic, also dyskinesia of biliary tract and other similar problems.
2. Headaches, as well as during migraine.
3. With dysmanifier, there are strong pains during menstruation in women.
4. With short-term pain in the joints and other systems of the body. As well as neuralgia, Malgia.

Novigan and interaction with the body

It should be noted that this medication is very well absorbed by the gastrointestinal tract.

The maximum concentration of the drug is achieved by about 1-2 hours. The same medicine is excreted together with the urine (90%). A small part of the ibuprofen component is excreted together with bile.

Novigan: Instructions for the use of this medication

How to take this correctly medicine? So it is important to remember that it is necessary to comply with the dosage. After all, only in this case can not harm your health.

So, the drug is accepted exclusively inside. The reception time is desirable to strictly withstand: either one hour before meals, or three hours after meals. However, if you want to avoid irritation of the gastric mucosa, the medicine can be taken immediately after eating. However, in this case, the action will come slightly later.

Attention: Maximum daily dose (Number of use) of this drug - 3 tablets. It is impossible to exceed this digit, because it is so harmful to your own health.

This medication can also be applied by a course of treatment. In this case, the number of accepted tablets should not exceed 15 pieces (3 pieces for 5 days). A longer treatment can be appointed only by the doctor. It will be undergoing under the strict control of blood and liver.

About overdose by the drug "Novigan"

So, the drug "Novigan". Indications for use - this item has already been considered. Now you need to say a few words about overdose. Is it possible to develop events? As already mentioned above, it is impossible to take more than 3 tablets "Novigan" per day. One of the reasons - possible overdose preparation. Symptoms that will testify to this:

• Nausea, vomiting.
• Painfulness in the stomach.
• Noise in ears.
• Headache.
• Depression, drowsiness.

In more serious cases, bradycardia can develop, pressure can be reduced. Also sometimes occur renal failure, Coma and even stop breathing.

What should I do if an overdose of Novigan is occurred? It is important to rinse the stomach immediately. However, this should happen no later than half an hour after taking the drug. Next, it is necessary to take activated carbon (dosage according to the patient's weight: 1 tablet at 7-8 kg of weight).

Useful will be an alkaline drink (for example, milk with soda), as well as forced diuresis (accelerated removal of the drug along with urine). Symptomatic therapy may also be needed, that is, actions depending on the manifestations of overdose. It is important to note that the only antidote from the overdose of "Novigan" is not.

Application "Novigan" during pregnancy and lactation

What should I remember, going to take the drug "Novigan"? Instructions for the use of this medication It says that it is strictly forbidden to use its use during a child tooling on any period (the drug itself is extremely negatively affecting the fetus), as well as in the period breastfeeding (the drug is able to absorb in breast milk And transfer to the child).

As part of 1 tablets contain active substances: 5mg pitoophenone hydrochloride , 400mg 0.1 mg. fenpiverinia bromide.

Auxiliary substances: 76mg corn starch, 5mg colloidal silicon dioxide, 4mg stearate Magnesium , 55mg MKC, 12mg Talc, 2,9mg .

The composition of the shell film shell: 1.124mg of macrogol 6000, 1,059mg titanium dioxide, 0.058mg sorbic acid , 5,686mg Halgonellose 6 CPS, 1,957 mg Talca, 0.058mg polysorbate 80, 0.058mg .

Form release

The drug is produced in the form of tablets in the shell of 10 pieces in a blister. The cardboard pack contains 2, 10 or 20 blisters with tablets, as well as instructions for use.

There is a form of release in tablets covered with film shell. In one blister there are 10 tablets. In the cardboard package there is an instruction on the use of the drug, as well as one or two blisters.

pharmachologic effect

Tablets are provided anti-inflammatory, analgesic and antispasmodic action.

Indications for the application of Novigan

Tablets Novyan are shown at:

• moderately or weakly pronounced pain syndrome observing when the smooth muscles of the internal organs is exposed - intestinal, biliary and, and also in case ;
• headache, including having a migrane nature;
• symptomatic short-term treatment when , malgia , ishiagia and pains in the joints.

Pharmacodynamics and pharmacokinetics

Novigan is combined drugwhich has spasmolytic, anti-inflammatory and analgesic actions. The medicine is inhibited synthesis. The preparation contains ibuprofen, which is a non-steroidal anti-inflammatory agent, bromide Fenpiverinia - M-choline-blocking agent having peripheral and central action, as well as myotropic antispasmodic pitoophenone hydrochloride.

Pitoophenone hydrochloride It causes the relaxation of the muscles of the internal organs, having a direct myotropic effect on it.

Ibuprofen(derived from phenylpropionic acid) It has analgesic, anti-inflammatory and antipyretic actions. The main effect of the substance is reduced to the oppression of synthesis. prostaglandinovwhich are modulators of thermoregulation, pain sensitivity and inflammation in peripheral tissues and CNS.. In women suffering from primary dysmenoria , Level is reduced prostaglandinov in myometryThereby reducing the heart rate and intrauterine pressure.

Fenpiverine Bromide It has an additional relaxing effect on the smooth muscles due to its cholin-blocking action.

Combining, these three main components are mutually reinforced pharmachologic effect each other.

Components included in Novigan are perfectly absorbed in Zhkt.. After receiving, approximately 1-2 hours later, the peak of the concentration of the drug is achieved. Ibuprofen, the main component of this medication, almost completely (by 99%) associated with blood plasma proteinsIt can also be accumulated in synovivial fluid. This component metabolized In the liver and 90% is displayed with the urine as conjugatov and. An insignificant part of Novigan along with bile is escructed. The half-life of the blood plasma is 2 hours.

Contraindications

The drug is contraindicated at:

• anamnestic data about the attack, bronchorate After reception acetylsalicylic acid or any other non-steroidal anti-inflammatory agent (with incomplete or complete syndrome of the intolerance of acetylsolicylic acid - krapivnice , polypakh nasal mucosa);
• inflammatory diseases of the intestine in the exacerbation phase, including ulcery ;
• erosive-ulcene changes in the mucous membrane duodenal gut or stomach, as well as with active bleeding in the gastrointestinal tract;
• active liver disease or liver failure;
• progressive kidney diseases or ( Cl. is less than 30ml / min);
• hemophilia or any other blood clotting disorders (including hangoagulation ), hemorrhagic diatelas ;
• confirmed hypercalemia ;
• acute intermittent porphyry ;
• bleeding disorders;
• tahiaritimia ;
• deficiency glucose-b-phosphatehydrogenase;
• granulocyptopenia ;
• closedugal ;
• intestinal obstruction;
• diseases spectator nerve ;
• period of breastfeeding or pregnancy;
• in the period after it was carried out aorticorial shunting;
• individual intolerance to the components contained in the preparation;
• age patient up to 16 years.

In addition, the drug should be taken with caution when:

• old age patient;
• cerebrovascular diseases;
• heart failure;
• hyperlipimedia /dyslipidemimia ;
• arterial hypertension ;
• C creatinine 30-60 ml / min;
• ischemic heart disease;
• neftyal syndrome ;
• hyperbirubinemia ;
• stagnant heart failure;
• peripheral arterial diseases;
• peptic disease duodenal and stomach (history);
• presence infections Helicobacter pylori. ;
• estrase ;
• long use of nonsteroidal anti-inflammatory agents;
• heavy somatic diseases;
• alcoholism or smoking;
• diseases of blood unclear etiology (anemia , leukopenia );
• concomitant therapy with anticoagulantov (eg, ), orally GKS. (eg, ), Antiagreganttov ( , acetylsolicylic acid etc.), as well as with SSRS (eg, , , Citalopram, ).

Side effects

For gastrointestinal tract: Pain in the mouth aphtose Stomatitis , the ulceration of the mucous membrane of the gastrointestinal tract, sometimes complicated by bleeding and perforation, the ulceration of the gum mucosa, NPVS-Gastropathy (nausea, heartburn, vomiting, lowering appetite, abdominal pain, ), in oral cavity may appear dryness and irritation of the mucous membrane ,.

For the respiratory system: bronchospasm, shortness of breath.

For the hepabolic system: hepatitis .

For peripheral and CNS: anxiety, dizziness, confusion of consciousness, insomnia, irritability and nervousness, hallucinations, psychomotor arousal , headache, drowsiness, and also butseptic which is most often observed in patients suffering autoimmune diseases.

For of cardio-vascular system: , increase hell, heart failure.
For the senses: violations - fuzzy spectacular perception, irritation and dryness of eyes, scotoma, edema and conjunctivatives, accommodation parires, as well as hearing impairment - its deterioration, as well as ringing or noise in the ears.

For blood formation organs: lakeing , anemia (including also hemolytic aplastic), thrombocytopenic purple and thrombocytopenia .

For the urinary system: acute renal failure allergic jade , oliguria , nephrotic syndrome (swelling), anuria , polyuria And urine is painted red.

Allergic reactions: fever, anaphylactoid reactions, dISPENE or bronchospasm, skin itch, multiform exudative erythema (including stevens-Johnson Syndrome ), eosinophilia , skin rash (usually hives or erythematose), toxic epidermal necroliz , allergic rhinitis .

Laboratory Indicators: Serum may decrease concentration glucosemay increase the time of bleeding, clearance can decrease creatininamay occur lower level or hematokritmay be elevated liver activity transaminazand can also be increased serum concentration creatinina.

Others side effects: Reduced or strengthening sweating.

In the event that changes have occurred in the usual state when taking the drug, it is necessary to immediately stop taking the drug and refer to the doctor without delay.

Instructions for applying Novigan (method and dosage)

The drug is accepted inside an hour before meals or after eating three hours later. To avoid the negative irritating effect of the drug on the stomach, you can receive new ones immediately after eating or you can drink tablets with milk.

In the absence of any doctor's prescriptions for receiving, spastic pains Novigan is recommended to take three times a day on one tablet. Maximum dose Taking the drug per day - three tablets Novyan.

Instructions for use also warned that without consulting a doctor, the rate of reception of the tablets should not last more than five days. If you need to use the drug for a longer time, then this is done only under the supervision of the doctor and the strict control of the indicators functional state Liver and peripheral blood.

Overdose

Symptoms of overdose are: inhibition, nausea, abdominal pain, drowsiness, vomiting, depression, metabolic acidosis , noise in ears, decrease in blood pressure, atrial fibrillation, headache, acute renal failure, Stop breathing and.

As a treatment, it is used: alkaline drink, washing the stomach (maximum - after 3 hours), forced diuresisand also assigned activated coal or symptomatic therapy is applied (adjusted arterial pressure, acid-main state). In this case, there is no specific drug that could be applied in case of overdose.

Interaction

When taking new people in therapeutic doses with other frequently used drugs, no significant interactions arise.

Microsomal oxidation inhibitors decreases the risk that will be developed hepatotoxic action.

In the liver inductors of microsomal oxidation enzymes ( ethanol., flumecinol, phenylbutazon, phenitonin, tricyclic antidepressants, barbiturates) Products of hydroxylated active metabolitesthereby increasing the risk that heavy inxication will develop.

Reduced sodiumstract effect and furosemide, as well as hypotensive activity of vasodilators.

Efficiency uricosuric Preparations decrease.

Increases the risk that bleeding will be developed due to the enhancement of the action fibrinolithics, indirect anticoagulantov and antiagreganttov.

Absorption ibuprofen decreases colestramor and antacidami.

The drug enhances the likely side effects, ethanol, GKS. (the danger increases that gastrointestinal bleeding occurs), mineralocorticosteroids; derivatives sulfonylmochina When interacting with the drug enhance your hypoglycemic effect.

Concentration in blood, as well as drugs methotrestat and lithium increases.
Simultaneous reception of the drug with other non-steroidal anti-inflammatory means increases the frequency of possible side effects.

Action is enhanced butyrofenonov, county, phenothiazinesblockers H1-histamine receptors, , m-cholinoblocators.

When the drug interacts with caffeine Increases analgesic effect.

In case of simultaneous reception with acetylsalicylic acid It decreases antiagregant and anti-inflammatory action (in patients who receive small doses of acetylsalicylic acid as an anti-aggregative agent, after applying Novigan is acute coronary insufficiency can develop with increased frequency).

The manifestations of the hematotoxicity of the drug increases myelotoxic LS..

In the case of the simultaneous use of Novigan C, valproevic acid, cephamandol, cefotetan or plikamcin Increases development rate hypoprothrombinemia .

Gold preparations and enhance the effect of substance ibuprofen on synthesis in the kidneys of PG, the effect of what is manifested in increasing nephrotoxicity. Plasma concentration, as well as the likelihood that its hepatotoxic effects will develop, increase by ibuprofen.

LS that block channel secretion, increase the plasma concentration of the substance ibuprofen, and also reduce its elimination.

Terms of sale

The drug is released in pharmacies without a recipe.

Storage conditions

The drug Novigan should be stored outside the accessibility from children in a dry place protected from light. The storage temperature should not exceed 25 ° C.

Shelf life

special instructions

When long use The drug requires careful control of the picture of the functional state of the kidneys and the liver and peripheral blood.

To reduce the risk of developing negative phenomena for gastrointestinal tract It is necessary to make a minimum effective dose of the drug. In case of symptoms gastropathy Careful control is required, which includes feces analysis for hidden blood, blood test, which includes definition hematokrit and as well as ezophagogastroduodenoscopy.

In case the definition is required 17 ketosteroids, It is necessary to stop receiving the drug 48 hours before the start of the study.

During the treatment with Novigan, it is necessary to refrain from drinking alcohol.

Patients taking drug should refrain from potentially hazardous activities for which the speed of psychomotor reactions and increased concentrations (management vehicles etc).

Newborn

The drug is contraindicated to the use of infants under the age of 4 months.

With alcohol

During the course of treatment with the drug, Novigan should refrain from use alcoholic beverages.

During pregnancy and lactation

During the period of pregnancy, the drug is contraindicated (especially should be refrained from the application in the first trimester and in the last six weeks of pregnancy), and it is also not recommended to take Novyans during breastfeeding period.

"Novigan", from which it helps this combined non-steroidal medicine? Antispasmodic drug It has pronounced analgesic and anti-inflammatory properties. "Novyans" instructions for use prescribes to take from spasms in the stomach and headaches.

Varieties and composition

The medicine is made in the form of pills covered with a shell. Active elements of the "Novigan" medication, from which he helps from pain of different origin, are:

1. Fenpiverine Bromide.
2. Pitoophenone hydrochloride.

Auxiliary components protrude: starch, talc, silicon dioxide, glycerol.

Tablets Novyan are packaged in a blister of 10 pieces. Cardboard pack contains 1 or 2 blisters with tablets, as well as instructions for use of the drug.

Therapeutic properties

Tablets "Novigan", from which are popular with many patients, have spasmolytic, analgesic and anti-inflammatory effect. The presence in its composition of ibuprofen determines the properties of the medication. Medicine also reduces increased temperature Body, thus creating an antipyretic effect.

The mechanism of action is based on a slowdown in the reproduction of prostaglandins, which are responsible for painfulness, Heat exchange in the body, inflammation processes. Antispasmodic effect Provide Pitoophenone hydrochloride and fenpiver bromide. The first active substance relaxes the muscles of the internal organs, the second strengthens this effect.

Tablets "Novigan": from what medicine helps

Indications include the following diseases and conditions:

• headache;
• dismenor;
• migraine;
• dyskinesia of jerry tract;
• spasms and colic (kidneys, intestines, bile);
• pain in Ishiagia, Malgia, Neuralgia;
• symptoms of pain in the joints.

Medicinal interaction

Tablets "Novigan" enhance the effect of alcohol, affect the speed of physical and mental reactions.

The drug reduces the diuretic effect of hypothiazide, furosemide. The use of a medication increases the effectiveness of fibrinolithics, hypoglycemic drugs, insulin and antiagregants. With simultaneous reception with potassium retention means, the risk of hypercalemia is increasing, in a complex with others nonteroid drugs Possible adverse reactions with stomach and intestines.

Preparation "Novigan": instructions for use

To eliminate pain of spasms, it is required to receive a tool three times a day for 1 piece. Tablets "Novigan", from which they help with algodismenorye, drink every 4 hours. To prevent the stomach irritation, the drug is desirable to take after eating, it is recommended to drink milk. Without appointing a specialist tablet, it is impossible to use more than five days.

Contraindications

The drug "Novigan" instructions for use prohibits accepting at:

• individual non-acceleration of active elements to other components;
• hypersensitivity to non-steroidal drugs;
• ailments of visual nerves;
• deviations in the work of the liver and kidneys;
• ulcers, erosions of the stomach and intestines;
• intestinal obstruction of acute character;
• hyperplasia prostatic gland;
• clothing type glaucoma;
• bronchial asthma;
• acute porphyria;
• aspirin triad, asthma;
• tahiaritimia;
• pregnancy;
• lactation;
• children and adolescents up to 16 years.

Caution during therapy is required to abide by people suffering chronic insufficiency Hearts, ulcers of the stomach and intestines, colitis in history, as well as with problems with blood reducing, the possibility of bronchospasm.

Sideflines

Medication "Novigan", instructions for use and reviews indicate this, can cause negative reactions of the body. After receiving medication, they can develop:

• allergy;
• accommodation;
• proteinuria;
• kidney dysfunction;
• paresis;
• oliguria;
• urine delay;
• tachycardia;
• urine dyeing;
• nephritis;
• anuria;
• dry mouth.

In case of overdose, violations of vision, nausea or vomiting, epigastrigation pain are observed.

Analogs and price

Buy the drug "Novigan", the price of which is about 90 - 125 rubles for 10 tablets, without a recipe. Preparencies for symptoms are able to replace the drugs: "Amazol", "", "and others. According to the current components of the Novigan medication, the analogues are absent.

Conditions of holiday and storage

Tablets Novigan in the pharmacy network are released without a recipe. In case of issues or doubt about their application, you should consult with your doctor.

The shelf life of Tablets Novigan is 5 years from the date of their manufacture. The drug must be stored in the original factory packaging, dark, dry, inaccessible for children. Place at air temperature not higher than + 25 ° C.

Opinions of patients

Positive feedback can be heard from the female half, from which the "Novyans" helps them in spasms during the period of menstruation. In some cases, relief occurs after 10 minutes, in other results, it is observed in an hour. However, the effectiveness is not doubtful.

Also confirm the reviews, Novigan helps from pain in the head. However, during migraine, the medicine gives relief not in all cases. On side effects after taking the drug "Novigan", the reviews are practically absent.