International name

Ginkgo biloba leaf extract (Ginkgo Bilobae foliorum extract)

Group affiliation

Angioprotective agent

Dosage form

Capsules, oral solution, film-coated tablets, film-coated tablets

pharmachologic effect

A drug vegetable origin, normalizes metabolism in cells, rheological properties of blood and microcirculation. Improves cerebral circulation and supply of the brain with oxygen and glucose, prevents the aggregation of erythrocytes, inhibits the platelet activating factor. It has a dose-dependent regulatory effect on the vascular system, stimulates the production of an endothelium-dependent relaxing factor, dilates small arteries, increases venous tone, thereby regulating blood circulation in the vessels. Reduces the permeability of the vascular wall (anti-edema effect - both in the brain and in the periphery). It has an antithrombotic effect (by stabilizing the membranes of platelets and erythrocytes, influencing the synthesis of Pg, reducing the action of biologically active substances and platelet-activating factor). Prevents the formation of free radicals and lipid peroxidation of cell membranes. Normalizes the release, reabsorption and catabolism of neurotransmitters (norepinephrine, dopamine, acetylcholine) and their ability to bind to receptors. Prevents an increase in the fibrinolytic activity of the blood. It has an antihypoxic effect, improves metabolism in organs and tissues, promotes the accumulation of macroergs in cells, increases the utilization of oxygen and glucose, and normalizes mediator processes in the central nervous system.

Indications

Dyscirculatory encephalopathy (stroke, TBI, old age), manifested following symptoms: decreased attention, weakened memory, decreased intellectual abilities, fear, sleep disturbances; disorders of peripheral circulation and microcirculation (including arteriopathy lower limbs), Raynaud's syndrome; neurosensory disorders (dizziness, tinnitus, hypoacusia), senile degeneration macular, diabetic retinopathy.

Contraindications

Hypersensitivity, hypocoagulation, acute cerebrovascular accident, acute myocardial infarction, gastric ulcer and 12 duodenal ulcer, erosive gastritis, pregnancy, lactation, childhood.

Side effects

Dyspepsia, headache, dizziness, insomnia (excluding Lf derived from ginkgo biloba extract EGB 761), allergic reactions(skin rash, itching).

Application and dosage

Inside, during meals, 40-50 mg or 1 ml of solution for oral administration (with an active substance content of 40 mg / ml) 3 times a day. Average duration treatment - 3 months.

special instructions

An improvement in the condition is manifested 1 month after the start of treatment.

Interaction

Avoid combination with ASA and anticoagulants.

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Do you use Tanakan as an analogue or vice versa its analogs?

Tanakan - angioprotective drug of plant origin, which improves cerebral and peripheral circulation.

The herbal composition ensures its mild and sparing effect on the body. Tanakan significantly improves microcirculation and has a beneficial effect on blood circulation in the brain.

Tanakan increases venous and arterial tone, provides the brain with an optimal amount of oxygen and glucose. Also, the drug has the ability to relieve edema of various localization.

Clinical and pharmacological group

Phytopreparation that improves cerebral and peripheral circulation.

Conditions of sale from pharmacies

Can buy without a doctor's prescription.

Price

How much does Tanakan cost in pharmacies? The average price is 600 rubles.

Composition and form of release

Tanakan dosage forms:

• Tablets: round, biconvex, brick-red film-coated; at the break - light brown (15 pcs. in blisters, in a cardboard box 2 or 6 blisters);
• Oral solution: brownish-orange in color, with a characteristic odor (30 ml each in dark glass vials, in a cardboard box 1 bottle complete with a 1 ml pipette-dispenser).

Composition of tablets (in 1 pc.):

• Active substance: ginkgo biloba leaf extract (EGb 761) - 40 mg, including flavonol glycosides - 22-26.4%, ginkgolides-bilobalides - 5.4-6.6%;
• Tablet core composition: lactose monohydrate, corn starch, microcrystalline cellulose, talc, colloidal silicon dioxide, magnesium stearate;
• The composition of the film shell: hypromellose (E464), titanium dioxide (E171), macrogol 400, macrogol 6000 and iron oxide red (E172).

The composition of the solution for oral administration (in 100 ml):

• Active ingredient: ginkgo biloba leaf extract (EGb 761) - 4000 mg, including flavonol glycosides - 24%, ginkgolides-bilobalides - 6%;
• Auxiliary components: sodium saccharinate, ethanol 96%, purified water, orange and lemon flavors.

pharmachologic effect

The herbal preparation Tanakan acts on the metabolic process in cells, improves microcirculation and rheological properties of blood. In addition, the drug normalizes the tone blood vessels organism, help to improve cerebral circulation and supply the brain with oxygen and glucose.

Other positive properties of Tanakan include inhibiting the aggregation of erythrocytes with inhibition of the platelet activating factor. When taking the drug, the maximum effect is achieved within 1-2 hours, and its bioavailability is 80-90%.

Indications for use

Tanakan is used in therapy:

• vertigo of vestibular origin;
• peripheral circulatory disorders. This pathology can also occur as a complication after Raynaud's disease;
• neurosensory disorders, which usually appear as a result of diabetic retino- / polyneuropathy and are manifested in tinnitus, hypoacusia, dizziness;
• dyscirculatory encephalopathies, which have a different genesis (post-stroke, senile, a consequence of traumatic brain injury), are manifested in the form of sleep disorders, attention, memory, decreased intellectual abilities;
• asthenic conditions. In such conditions, patients have symptoms of general depletion of the body, which are the result of traumatic, neurotic, psychogenic processes.

Contraindications

• exacerbation period peptic ulcer stomach and duodenum;
• acute myocardial infarction;
• decreased blood clotting;
• acute disorders of cerebral circulation;
• exacerbation of erosive gastritis;
• pregnancy and lactation;
• age under 18;
• hypersensitivity to any component of the phytopreparation;
• glucose / galactose malabsorption syndrome, lactose intolerance, congenital galactosemia, lactase deficiency (for tablets).

Tanakan solution should be taken with caution in the presence of the following conditions / diseases:

• liver disease;
• traumatic brain injury;
• brain diseases;
• alcoholism.

Appointment during pregnancy and lactation

There is no clinical experience with the use of tablets and Tanakan solution among women carrying a child, so the drug is not recommended to be prescribed to expectant mothers. It is not known how the therapy may affect the fetal development of the baby.

It is not known whether the active substance of the drug is excreted with breast milk and how this might affect a child in breastfeeding... Given this information, tablets and a solution of the drug should not be prescribed to nursing mothers, and if therapy is necessary, it is recommended to decide on the termination of lactation.

Dosage and method of administration

As indicated in the instructions for use, Tanakan is prescribed for adults by mouth at 40 mg (1 tab. Or 1 ml of oral solution) 3 times / day with meals. The tablet should be taken with half a glass of water.

The oral solution should be dissolved in half a glass of water. When taking the drug in the form of a solution for oral administration, use the supplied pipette-dispenser (1 dose = 1 ml of solution).

The minimum course of treatment is at least 3 months. An increase in the duration and repeated courses of treatment is possible on the recommendation of a doctor.

Side effect

The use of the drug can cause the following side effects: headache, dizziness, rash, eczema, itching, nausea, abdominal pain, diarrhea, decreased blood clotting and dyspepsia.

Long-term use of Tanakan may lead to a risk of bleeding.

Overdose

Currently, not a single case of drug overdose has been recorded.

special instructions

Before you start using the drug, read the special instructions:

1. Before using the drug, you need to consult a doctor.
2. An improvement in the condition is manifested 1 month after the start of treatment.
3. One single dose of oral solution contains 450 mg ethyl alcohol(57% v / v), at maximum daily dose- 1.35 g of ethyl alcohol.

During the period of taking the drug, it is not recommended to perform potentially dangerous species activities requiring increased concentration of attention and speed of psychomotor reactions (including management vehicles, work with moving mechanisms), because the drug may cause dizziness and the solution contains ethyl alcohol.

Interaction with other drugs

The drug should not be used in patients who systematically receive acetylsalicylic acid (as an antiplatelet agent), anticoagulants (direct and indirect action) and other drugs that reduce blood clotting.

V clinical research with EGb 761, both inhibition and induction of cytochrome P450 isoenzymes were found. When EGb 761 was taken together with midazolam, the level of the latter changed, presumably due to the effect on CYP3A4. Thus, care must be taken when taking EGb 761 together with drugs metabolized using the CYP3A4 isoenzyme and having a low therapeutic index.

With the simultaneous use of Tanakan in the form of an oral solution with antibiotics of the cephalosporin group (cefamandol, cefoperazone, latamoxf), gentamicin, chloramphenicol, disulfiram, thiazide diuretics, anticonvulsants, oral hypoglycemic drugs (chlorpropamide, glibenclamine lactic acidosis)), antifungal drugs(griseofulvin), 5-nitroimidazole derivatives (metronidazole, ornidazole, secnidazole, tinidazole), ketoconazole, cytostatics (procarbazine), tricyclic antidepressants, tranquilizers, such reactions as hyperthermia, hyperemia, skin hyperemia may occur. the form of a solution for oral administration contains 450 mg of ethyl alcohol.

Hello friends! Today we will talk about tanakan, whose analogues are very common everywhere.

Therefore, our main task will be to figure out whether analogs are really of this drug just as effective.

I would also like to tell you about its cost and how to use it for children.

Tanakan analogues

The main active ingredient of this remedy is the leaves of ginkgo biloba, better known as ginkgo biloba. The extract from this plant helps to improve cerebral and peripheral circulation.

It is worth saying that the demand for medicines of this type is growing, and, as a result, every year more and more analogues appear on the pharmaceutical market, which include:

1. Ginos.
2. Vitrum Memori.
3. Gingium.
4. Ginkoba.
5. Ginkoum.
6. Ginkgo biloba.
7. Ginkging and many others.

However, one of the main analogs is still Bilobil. Currently, it is very popular, so it can be found in almost every pharmacy.

True, if we are talking about tanakan, the analogue of Bilobil has almost the same cost.

This is due to the fact that everything medications containing ginkgo biloba extract are very expensive. Plus their production is very beneficial for pharmaceutical companies.

Food for thought ...

The main advantages of this type of medication is that they can influence the changes occurring in the blood circulation, inhibiting them.

Once again, I repeat that, like tanakan, analogues include ginkgo biloba extract, so they differ little from the product itself.

However, the form of release may be different. The most popular are pills and oral mixtures.

If we talk about pharmachologic effect, then it is based on:

• Activity of vasomotor reactions.
• Improving blood rheology.
• Strengthening cellular processes.
• Improving cerebral circulation by increasing the supply of oxygen and glucose.

Tanakan for children

Parents often have a question about its use in childhood, therefore, I decided to reveal this question a little.

If we consider the annotation, then we can conclude that the drug is absolutely safe, therefore it can be taken in childhood. True, few parents believe this.

In fact, this tool includes exclusively herbal ingredients. It is able to minimize disturbances in vegetative - vascular system as well as improve cerebral circulation.

It is because of this that doctors prescribe tanakan for children. However, with such use, the dosage must be strictly observed, which can only be established by a doctor - a neurologist for each individual case.

Important to remember!

In no case should you take the medicine yourself, relying on the advice and results of friends. Only a doctor is able to determine the dose that is suitable for the baby, as well as the number and duration of receptions.

Do not forget about the contraindications that exist for children. Contraindications include:

• lactose intolerance,
• hypersensitivity to the components of the drug,
• lactose deficiency and chronic diseases digestive system.
• Otherwise, it is safe and can be prescribed not only to infants, but also to newborn children.

How much is a tanakan

Now let's figure out how much it costs. As noted earlier, the price for it is very high, however, it is better not to save on it.

Tanakan is a popular herbal extract derived from the leaves of the rare Ginkgo biloba tree. The purpose of the drug is to improve blood circulation, primarily cerebrovascular, as well as blood circulation in peripheral tissues. Many people suffering from cerebrovascular accidents have become convinced of its effectiveness. However, Tanakan is an imported drug, and not everyone can afford it. Therefore, in many cases, it is quite reasonable to resort to the use of analogues of the drug, usually having more affordable price... Another reason why Tanakan may not be suitable for a patient is intolerance to its components. Fortunately, in pharmacies you can find many drugs that can replace Tanakan.

Tanakan - principle of action, composition and dosage

But first, let's tell you a little about the original drug. It is produced by the French pharmaceutical company Bofur Ipsen Industry is currently sold in 60 countries around the world. The preparation contains an extract obtained from the leaves of the ginkgo biloba tree grown on special plantations in North America. Therapeutic effect extract is explained by the presence of many biologically active compounds in it:

• flavonoids,
• terpenes,
• ginoclids,
• bilobaids.

Preparations containing ginkgo extract have the following types of effects on the body:

• enrich the brain tissue with glucose and oxygen,
• improve blood microcirculation,
• stabilize venous and arterial tone,
• reduce the intensity of thrombus formation,
• prevent the aggregation of erythrocytes,
• have an antihypoxic effect on tissues,
• prevent the formation of free radicals,
• prevent the oxidation of lipids that make up the cell membranes.

The main dosage form Tanakana - 40 mg tablets. Usually 1 tablet is prescribed 3 times a day with meals. There is also a solution of the drug for oral administration. 1 ml of solution contains 40 mg of ginkgo extract. The solution is also taken in 1 ml 3 times a day with meals. Before taking, the solution must be diluted in a small amount of water.

Tanakan is a drug for a long-term course of administration, and the duration of therapy is usually at least 3 months.

Indications for the use of the drug:

• encephalopathy;
• chronic disorders of cerebral circulation;
• circulatory disorders in peripheral tissues;
• obliterating endoarteritis;
• decreased visual acuity;
• hearing impairment;
• Raynaud's syndrome;
• recovery from ischemic stroke;
• atherosclerosis;
• violations of the ability to memorize information, concentration and attention;
• dizziness;
• sleep disturbances;
• increased fatigue, decreased performance;
• decreased immunity;
• rehabilitation after traumatic brain injury;
• asthenic conditions caused by trauma or depression;
• disorders of coordination of movements.

Tanakan is not recommended for use in childhood, and for women during pregnancy and lactation. The reason is the insufficient amount of data indicating the safety of the drug during these periods. You should not take the drug if:

• peptic ulcer of the stomach and duodenum,
• exacerbation of erosive gastritis,
• acute violation of cerebral circulation,
• poor blood clotting.

• itching
• edema,
• redness of the skin,
• eczema,
• skin rashes
• nausea
• vomiting
• abdominal pain
• headaches
• dizziness
• tinnitus
• bleeding (with prolonged use),
• decreased blood clotting.

Analogs

Not all preparations that can be attributed to Tanakan analogs contain ginkgo biloba extract. Some preparations contain other active substances such as memantine. Memantine preparations are most often recommended as a substitute for ginkgo preparations. Memantine is effective for diseases such as Alzheimer's, multiple sclerosis, Parkinson's disease, dementia of various origins.

However, when replacing Tanakan with similar drug it is recommended to ask a doctor for advice, since the selected analogue may not be suitable for contraindications and indications.

Those preparations that contain ginkgo biloba extract as an active substance usually also have a dosage of 40 mg. Although there are pills with a different dosage.

The most popular drugs with an effect close to that of Tanakan:

• Abix,
• Bilobil intensity,
• Vitrum memory,
• Gingium,
• Ginkgo biloba extract,
• Ginkgogink,
• Ginkgoum,
• Ginkofar,
• Ginkyo,
• Ginkoba,
• Ginos,
• Intellan,
• Meme,
• Memantidex,
• Memantine,
• Membral,
• Memoplant,
• Memorin,
• Noodzheron,
• Cerebroton.

The table below shows the main parameters of the most popular drugs.

Name	Release form	Active ingredient	Dosage	Manufacturer	Country
Abyx	pills	memantine	10 mg	Lundbeck	Denmark
Bilobil Intens	capsules	ginkgo extract	120 mg	KRKA	Slovenia
Bilobil	capsules	ginkgo extract	40 mg	KRKA	Slovenia
Bilobil Forte	capsules	ginkgo extract	80 mg	KRKA	Slovenia
Vitrum Memori	pills	ginkgo extract	60 mg	UNIPHARM	USA
Gingkokaps-M	capsules	ginkgo extract	40 mg	Monfarm	Ukraine
Ginkoum	capsules	ginkgo extract	40/80 mg	Evalar	Russia
Ginkgo biloba	capsules	ginkgo extract	40/80 mg	Vertex	Russia
Ginkgo biloba Evalar	capsules	ginkgo extract, glycine	120 mg (ginkgo extract)	Evalar	Russia
Ginkofar	pills	ginkgo extract	40 mg	Biofarm Ltd	Poland
Ginos	pills	ginkgo extract	40 mg	Veropharm	Russia
Intellan	capsules	extracts of ginkgo, centella, herpestis, coriander, amomum, emblica	50 mg (ginkgo extract)	HERBION INTERNATIONAL	Pakistan
Meme	pills	memantine	10 mg	Actavis Group	Ireland
Memantine-Richter	pills	memantine	10 mg	Gedeon Richter	Hungary
Memantine-Canon	pills	memantine	20 mg	Canonpharm	Russia
Memantine-Ozone	pills	memantine	10/20 mg	Ozone	Russia
Memantidex	pills	memantine	10 mg	Lesvi Laboratories	Spain
Membral	pills	memantine	10 mg	Kiev Vitamin Factory	Ukraine
Memoplant	pills	ginkgo extract	80 mg	Wilhelm Schwabe	Germany
Memorin	oral drops	ginkgo extract	1 ml / 40 mg	Zhytomyr FF	Ukraine
Ginkogink	solution	ginkgo extract	1 ml / 40 mg	Biogalenique	France
Noodzheron	pills	memantine	10 mg	PLIVA HRVATSKA	Croatia
Cerebroton	pills	extracts of ginkgo and multispecies	50 mg (ginkgo extract)	Biotechnos	Romania

Prices for Tanakan and its most affordable counterparts

Drug name	Number of units or volume	Price from
Bilobil Intens	60 capsules	890 p.
Bilobil Intens	20 capsules	430 p.
Bilobil Forte	60 capsules	620 p.
Bilobil Forte	20 capsules	300 p.
Bilobil	60 capsules	540 p.
Ginkgo biloba Evalar	60 capsules	600 RUB
Ginkgo biloba Vertex 80 mg	30 capsules	180 p.
Ginkgo biloba Vertex 40 mg	30 capsules	130 p.
Ginkoum 40 mg	90 capsules	650 RUB
Ginkoum 80 mg	60 capsules	530 p.
Ginos	30 tablets	190 p.
Intellan	20 capsules	190 p.
Memantine-Richter	30 tablets	430 p.
Memantine-Canon 20 mg	90 tablets	4420 p.
Memantine-Canon 20 mg	30 tablets	1880 p.
Memantine-Canon 10 mg	30 tablets	682 p.
Memantine-Ozone 10 mg	60 tablets	890 p.
Memantine-Ozone 20 mg	30 tablets	1740 p.
Memoplant 80 mg	30 tablets	850 p.
Memoplant 40 mg	60 tablets	970 p.
Memoplant 40 mg	30 tablets	510 p.
Tanakan 40 mg	90 tablets	1370 p.
Tanakan 40 mg	30 tablets	540 p.
Tanakan solution	30 ml	530 p.

The medicine Tanakan contains as an active substance Ginkgo biloba leaf extract ... The core of the tablets includes such auxiliary components as lactose monohydrate, corn starch, talc, MCC, colloidal silicon dioxide, magnesium stearate. The shell contains hypromellose, macrogol 6000, red iron oxide, macrogol 400, titanium dioxide.

Additional ingredients of the solution: sodium saccharinate, lemon flavor, water, orange flavor, ethanol 96%.

Release form

Pharmacies sell Tanakan biconvex film-coated tablets. In addition, a brown-orange solution is commercially available.

pharmachologic effect

Angioprotective a herbal preparation that improves cerebral circulation.

Pharmacodynamics and pharmacokinetics

This medicine is standardized and titrated a product with a herbal composition. Its action is based on the influence on metabolic processes in cages, vasomotor reactions and rheological properties .

Tanakan contributes to the enrichment of the brain with oxygen and glucose, normalizes microcirculation, tone of arteries and veins. In addition, it improves blood flow, has an inhibitory effect on activation factor , prevents aggregations .

The drug also normalizes, prevents the formation of free radicals and fat peroxidation of cell membranes, has antihypoxic action on tissue. Drug affects release, catabolism, and reuptake neurotransmitters , as well as the ability to contact membrane receptors .

Bioavailability ginkgolides and bilobalides is 80-90%. The maximum concentration is reached after about 1-2 hours. The half-life is 4-10 hours. The active substance does not disintegrate and is almost completely excreted in the urine. A small amount - with feces.

Indications for Tanakan's use

Indications for Tanakan's use are as follows:

• treatment cognitive impairment in the elderly (except, vascular disorders , violations metabolism );
• symptomatic treatment of tinnitus;
• therapy vertigo ;
• intermittent claudication in case of chronic obliterating arteriopathies lower limbs;
• and coordination disorders vascular origin ;
• disease and .

Contraindications

The use of the drug is contraindicated in the following cases:

• exacerbation erosive gastritis ;
• acute disorders of cerebral circulation;
• reduced clotting ;
• children's age (up to 18 years old);
• aggravation;
• spicy ;
• hypersensitivity to the components of the drug.

The description of the pills also indicates that they should not be taken with congenital galactosemia , lactose intolerance , disadvantage lactase , glucose malabsorption syndrome or galactose .

With caution, if there are indications for the use of Tanakan, the solution is used in the event that TBI , liver and brain diseases.

Side effects

In rare cases, when taking the medication, the following side effects are observed:

• Gastrointestinal tract: digestive disorders, nausea, painful sensations in the abdomen, vomiting;
• skin: skin inflammation, redness, rash,;
• the immune system: hypersensitivity reactions, including;
• CNS: , syncope , .

If there are side effects, you must stop taking the product and consult a specialist.

Instructions for use of Tanakan (Way and dosage)

The drug is intended for internal use adult patients. This should be done 3 times a day with meals.

For patients who take Tanakan tablets, the instructions for use advise them to drink ½ glass of water.

The solution is diluted in half a glass of water. When using it, you must use the attached to the drug pipette-dispenser .

Therapy lasts at least 3 months. Extend the course and conduct re-treatment should be done only after consulting a doctor, only he knows what the medicine can help in each case.

Instructions for the use of Tanakan for children informs that this remedy should not be given to patients under 18 years of age.

Overdose

Overdose Information drug not provided.

Interaction

Interaction with funds metabolizable with isoenzyme CYP3A4 and with low therapeutic index should be handled with caution.

Tanakan should not be used in combination with drugs that include acetylsalicylic acid , drugs that lower blood clotting , and anticoagulants .

Combination with group cephalosporins , , thiazide diuretics , oral hypoglycemic agents , 5-nitroimidazole derivatives , cytostatics , tranquilizers , anticonvulsants LS, antifungal drugs, tricyclic antidepressants may cause hyperthermia , vomiting, heart palpitations.

Terms of sale

The medicine is sold by prescription.

Storage conditions

The product must be kept in a container at temperatures up to 25 ° C. It must be kept out of the reach of children. Ginkofar , Memoplant , Memorin , Ginkgo Biloba-Astrafarm .

Memoplant or Tanakan - which is better?

Many patients are interested in the question: Memoplant or Tanakan - which is better? Experts say that it is impossible to unequivocally answer this question, since both drugs are almost identical. Basically, they differ by manufacturers. Memoplant is produced by a German company, and Tanakan is produced by a French company.

Tanakan for children

Children under 18 years of age should not be given the drug. Tanakan is contraindicated for children, although some doctors still prescribe it.

With alcohol

There is no exact data on compatibility with alcohol. However, it should be borne in mind that the medicine contains alcohol.

Reviews about Tanakana

Patients leave a variety of comments about Tanakana on the forums. Basically, they write that the tablets or solution helped. However, there are reviews of Tanakana that report side effects... Mostly people write about the appearance and .