Composition

The composition includes an active substance drotaverine hydrochloride .

1 tablet contains 40 or 80 mg of this substance. Additional elements: talc, potato starch, povidone, magnesium stearate, lactose monohydrate.

1 ml of solution for injection contains 20 or 40 mg of active substance.

1 ml of solution for i / v and i / m contains 20 or 40 mg of the active substance, as well as additional elements: injection water, sodium disulfite and ethanol.

Release form

It is produced in the form of tablets, solution for injection, as well as in ampoules for intravenous and intramuscular administration.

pharmachologic effect

What is Drotaverin? it myotropic antispasmodic ... Has a vasodilator effect.

Pharmacodynamics and pharmacokinetics

In comparison with papaverine, it has a longer and more pronounced effect, despite the similarity of pharmacological properties and chemical structure. The mechanism of action is aimed at reducing the flow of calcium into smooth muscle tissue. Drotaverine hydrochloride expands blood vessels, reduces intestinal motility , tone of smooth muscle tissue internal organs... The drug does not affect the functioning of the autonomic nervous system, does not pass through blood-brain barrier ... The drug is prescribed if it is impossible to use m-anticholinergics. At intravenous administration the effect develops in 4 minutes, the maximum is recorded in half an hour. It is excreted to a greater extent by the kidneys and to a lesser extent - with bile.

Indications for the use of Drotaverin

Drotaverin solution and tablets - what are they from? The drug is prescribed for the prevention and treatment of biliary dyskinesia, biliary colic , spasm of smooth muscle tissue, dyskinesia of the gallbladder , cholecystitis, pyelitis, postcholecystectomy syndrome, intestinal colic, pilospasm, proctitis, spastic colitis, spastic, gastroduodenitis. Often used for menstruation.

What else does the drug Drotaverin help from? Indications for the use of the drug are also: vascular spasm, endarteritis, postpartum contractions, prolonged opening of the pharynx, throat spasm during delivery, threatening miscarriage, algodismenorrhea conducting cholecystography.

Contraindications

Drotaverin is not prescribed for atrioventricular blockade, cardiogenic shock, renal and hepatic system failure. With, total, breastfeeding, are prescribed after consulting specialists.

Side effects

Drotaverine may cause fever, palpitations, drop in blood pressure, increased sweating. When administered intravenously, collapse, respiratory depression may develop.

Instructions for use of Drotaverin (Way and dosage)

Drotaverin tablets, instructions for use

The drug is prescribed for adults three times a day by mouth, 40-80 mg. No more than 240 mg.

Drotaverin injections, instructions for use

Subcutaneously and intravenously injected 1-3 times a day, 40-80 mg. In order to relieve renal and hepatic colic, 40-80 mg is slowly injected intravenously. Intra-arterial administration is acceptable for peripheral vascular spasm.

For children

Children from 3 to 6 years of age can be administered 10-20 mg at a time, no more than 120 mg per day. 2-3 doses per day are acceptable.

Overdose

Overdose is manifested by a violation atrioventricular conduction , paralysis of the respiratory center, cardiac arrest, decreased excitability of the heart muscle.

Interaction

The drug is capable of weakening the effect antiparkinsonian drugs (for example, ). The drug enhances the effectiveness of antispasmodics. While taking procainamide, tricyclic antidepressants , quinidine drop is recorded. Reduces the spasmodic effect of morphine. Phenobarbital enhances the effect of the medication.

Terms of sale

No recipe needed.

Storage conditions

Store in a dark, dry place, out of the reach of children, at a temperature not exceeding 25 degrees Celsius.

Shelf life

No more than 3 years.

special instructions

Drotaverine is combined with antiulcer drugs in the treatment peptic ulcer digestive tract. Therapy involves refusal to perform complex activities, driving vehicles.

OKPD code 24.42.13.727

Recipe in Latin:

Rp .: Tab. Drotaverini 0.04
D. t. d. No. 20 in tabul.
S.

Drotaverine during pregnancy

The drug is contraindicated during this period of life. However, doctors still prescribe a medication when the potential benefit from using the drug is higher. possible risk for the future baby.

What is Drotaverinum for during pregnancy? The tool is used to get rid of muscle spasms of internal organs, that is, for example, to relieve uterine tone. It should be remembered that these situations are exceptional and you should not take this medication uncontrollably.

Analogs

Medicines are analogous to Dolce , , Spazoverin .

What is better Drotaverin or No-shpa?

The drugs are generally similar, since they have a similar effect and the same active substance. So Drotaverin is No-shpa in essence the same. However, No-shpa is a more expensive product, since it is of imported origin.

When choosing No-shpu or Drotaverin, you should also remember that the latter is not a patented medicine.

Reviews about Drotaverin

An excellent and effective substitute for No-shpa, an inexpensive drug with a good analgesic effect.

Of the minuses, they note: the remedy does not always help, it tastes bitter, sometimes the tongue can go numb from it, there are also contraindications.

Drotaverin price where to buy

The price of Drotaverin in tablets of 40 mg is 20 rubles per pack of 20 pieces.

Drotaverin Forte 80 mg costs 50 rubles per pack of 20 pieces.

10 ampoules of 2 ml cost 60 rubles.

• Online pharmacies in Russia Russia
• Online pharmacies of Ukraine Ukraine
• Internet pharmacies in Kazakhstan Kazakhstan

ZdravCity

Drotaverin tablets 40mg No. 20 Organic JSC Organic

Drotaverin tab. 40mg No. 50 Ozone OOO

Drotaverin-ellara solution in / in and in / m 2% 2ml n10 ELLARA LLC

Drotaverin velpharm tab. 40mg No. 50 Velpharm OOO

Drotaverin ms tab. 40mg No. 20 JSC Medisorb

Pharmacy Dialog

Drotaverina hydrochloric acid (tab. 40mg No. 28)

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Drotaverine hydrochloric acid (tab. 40mg No. 50)

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Drotaverin 40 mg No. 50 tab Uralbiopharm OJSC

Drotaverin 40 mg n20 tab OZON, OOO

Drotaverin injection 20 mg / ml 2 ml n10 ampDeco Company Ltd.

The drug Drotaverin belongs to the group of myotropic antispasmodics. In its structure and effect on smooth muscles, the drug is similar to papaverine, but it has a more pronounced therapeutic effect... Reduces the tone of smooth muscles of internal organs and intestinal motility, dilates blood vessels.

Drotaverin is most often used for various pains of a spasmodic nature, although it is not an anesthetic.

Removing the spasm of the muscles or blood vessels, drotaverine thereby eliminates the cause that caused the pain.

The main active ingredient of the drug is drotaverine hydrochloride. Injection. Ampoules of 2 ml contain 40 mg of the active ingredient drotaverine hydrochloride. Tablets with a dosage of 40 mg of active ingredient.

Forte tablets with an increased dosage of 80 mg of the substance.

Indications for the use of Drotaverin

As a preparatory tool for patients referred to various procedures, for example, ureteral catheterization.

Before carrying out diagnostic studies (cholecystography, urography, cystoscopy and others).

As symptomatic therapy, in the case when pain is the main characteristic accompanying manifestation of the disease, but does not play a leading role in its pathogenesis: renal and hepatic colic, intestinal colic caused by smooth muscle spasm, pyelitis, cholecystitis, pyloric stenosis, cerebrovascular spasm and coronary arteries, tenesmus - false urge to defecate, spastic constipation.

• Threatening spontaneous abortion against the background of hypertonicity of the uterus.
• Spasm of the pharynx of the uterus during labor.
• To facilitate postpartum uterine contractions.
• In the treatment of spasms of the gastrointestinal tract, Drotaverin is used as part of a combination therapy.
• Drotaverine can be used in complex therapy hypertensive crisis.

Instructions for the use of Drotaverin, dosages

Drotaverin injections

Drotaverine hydrochloride solution for injection is administered intramuscularly. The duration and dose are also calculated individually. The usual adult dose is 2-4 ml 1 to 3 times a day.

In rare cases, with violations of peripheral circulation, the drug is slowly administered intra-arterially.

It must be remembered that Drotaverine solution should be used only in acute conditions or when it is impossible to take tablets. As soon as the acute condition is removed, or the person can swallow the pills, the injection should be stopped and the drug should be taken internally by Drotaverin.

Drotaverin tablets

The tablets are drunk at any time of the day, without chewing.

Adults: The usual average dose is 120-240 mg per day in 2-3 divided doses.

You can take the drug up to 80 mg (2 tablets) per dose, up to three times a day. The effect begins to be observed approximately 15 minutes after ingestion, but the maximum effectiveness is achieved after 40-45 minutes.

The time of oral administration of the drug does not depend on the time of the meal. The duration of the course is determined individually in each case by the doctor.

Children (Drotaverin is used internally):

- children from 1 to 6 years old are prescribed 1/4 - 1/2 tablets 1 - 2 times a day;
- children 6 - 12 years old - 1/2 tablet 1 - 2 times a day,
- over 12 years old - 1 tablet 2 times a day.

Application features

Taking the drug is not compatible with the use of alcoholic beverages.

The use of the drug for more than 3 days and / or the use of high doses requires monitoring the picture of peripheral blood and functional state liver.

Injection can worsen the speed of psychomotor reactions, therefore, for an hour after each injection, you should refrain from practicing potentially dangerous species activities requiring high concentration attention

If patients after oral administration dizziness is observed, they should avoid potentially hazardous activities, such as driving and performing work that requires increased attention.

Side effects and contraindications Drotaverin

• With intravenous administration, depression of the respiratory center was noted.
• When administered intravenously, blood pressure may decrease.
• Increased heartbeat (arrhythmia, tachycardia).
• Feeling hot.
• Development of AV blockade.
• Increased sweating (hyperhidrosis).
• Dizziness.
• Vomiting or nausea.
• Fainting, disturbance of sleep and wakefulness.
• Bronchospasm and slight swelling of the nasal mucosa.
• Itching, Quincke's edema, skin rash, allergic dermatitis.

Overdose

In case of an accidental overdose of medication, an increase in side effects and the occurrence of the following phenomena:

• pallor of the skin;
• sweating;
• nausea;
• vomit;
• respiratory depression;
• vascular insufficiency;
• AV block;
• paralysis of the respiratory center;
• heart failure.

There is no specific antidote.

Treatment is symptomatic: gastric lavage, intake of saline laxatives. In case of overdose, the patient should be under medical supervision.

With atrioventricular block, atropine and isoprenaline are used intravenously, in case of cardiac arrest, the use of atropine or adrenaline intravenously and temporary cardiac stimulation are indicated, in case of respiratory arrest due to paralysis of the respiratory center, it is shown artificial ventilation lungs.

Contraindications (common for both dosage forms):

• hypersensitivity
• cardiogenic shock,
• arterial hypotension,
• angle-closure glaucoma,
• adenoma prostate,
• severe hepatic and renal failure,
• deficiency of lactose,
• severe heart failure
• lactation period,
• angle-closure glaucoma,
• children up to age 3 years.

Carefully. Severe atherosclerosis of the coronary arteries.

Drotaverin analogs, list

1. Bioshpa;
2. Spasmol;
3. Spazmonet;
4. Nikoverin;
5. Papazol;
6. Platyphyllin;
7. Spakovin.

The drug is synonymous with the popular drug No-shpa. Important - the instructions for the use of Drotaverin, the price and reviews do not apply to analogues and cannot be used as a guide for the use of drugs of similar composition or action. All therapeutic appointments must be made by a doctor. When replacing Drotaverin with an analogue, it is important to consult a specialist, you may need to change the course of therapy, dosages, etc.

Do not self-medicate!

Gross formula

Pharmacological group of the substance Drotaverin

Nosological classification (ICD-10)

CAS code

Characteristics of the substance Drotaverin

Crystalline powder of light yellow color, odorless. Let's dissolve in water and alcohol.

Pharmacology

Reduces the flow of ionized active calcium into smooth muscle cells by inhibiting phosphodiesterase and intracellular accumulation of cAMP. It is quickly and completely absorbed in the gastrointestinal tract. When taken orally, bioavailability is close to 100%, and the half-absorption period is 12 minutes. It is evenly distributed over the tissues, penetrates into smooth muscle cells. Excreted by the kidneys.

Explicitly and for a long time expands the smooth muscles of the internal organs and blood vessels, lowers blood pressure, increases the cardiac output. Virtually no effect on vegetative nervous system and does not penetrate the central nervous system.

Application of the substance Drotaverin

Spasm of smooth muscles of internal organs (cardio and pylorospasm), chronic gastroduodenitis, gastric ulcer and duodenum, gallstone disease (hepatic colic), chronic cholecystitis, postcholecystectomy syndrome, hypermotor dyskinesia of the biliary tract, spastic intestinal dyskinesia, intestinal colic due to gas retention after surgery, colitis, proctitis, tenesmus, flatulence, urolithiasis (renal colic), pyelitis, spasm of cerebral vessels, coronary and peripheral arteries, the need to weaken uterine contractions and removal of cervical spasm during childbirth, smooth muscle spasm during instrumental interventions.

Contraindications

Hypersensitivity, glaucoma.

Restrictions on use

Adenoma of the prostate gland, pronounced atherosclerosis of the coronary arteries.

Application during pregnancy and lactation

Side effects of the substance Drotaverin

Feeling of heat, dizziness, arrhythmias, hypotension, palpitations, sweating (more often with parenteral administration), allergic dermatitis.

Interaction

It enhances (especially with intravenous administration) the effect of other antispasmodics (including m-anticholinergics), hypotension caused by tricyclic antidepressants, quinidine, novocainamide. The reliability of elimination of spasm increases phenobarbital. Reduces the spasmodic activity of morphine, antiparkinsonian properties of levodopa.

Overdose

AV block, cardiac arrest, paralysis of the respiratory center.

Route of administration

Inside, i / m, s / c.

Interaction with other active ingredients

Trade names

Tradename: Drotaverin

International (non-proprietary) name: drotaverine

Chemical rational name: 1- (3,4-diethoxyphenyl) methylene-6,7-diethoxy-1,2,3,4-tetrahydroisoquinoline (as hydrochloride).

Dosage form: pills

Composition

One tablet contains:

active substance: drotaverine hydrochloride 40 mg;

Excipients: potato starch, lactose monohydrate (milk sugar), povidone (polyvinylpyrrolidone), talc, magnesium stearate.

Description

Round tablets of yellow color with a greenish tinge, flat-cylindrical shape with beveled and scored.

Pharmacotherapeutic group: antispasmodic.

ATX code: A03AD02

Pharmacological properties

Myotropic antispasmodic, isoquinoline derivative. Inhibits phosphodiesterase (PDE) IV, which leads to the accumulation of intracellular cyclic adenosine monophosphate (cAMP) and, as a consequence, to inactivation of the light chain of myosin kinase, resulting in relaxation of smooth muscles. Regardless of the type of autonomic innervation, drotaverine acts on smooth muscles in gastrointestinal tract, biliary, genitourinary and vascular systems. In the myocardium and blood vessels, the enzyme that hydrolyzes cAMP is PDE III, which explains the absence of serious side effects from of cardio-vascular system(CVS) and unexpressed therapeutic effect on CVS.

The presence of a direct effect on smooth muscles makes it possible to use it as an antispasmodic in cases when drugs from the group of m-anticholinergics are contraindicated (angle-closure glaucoma, prostatic hyperplasia).

Pharmacokinetics. When taken orally, absorption is high, the half-absorption period is 12 minutes. Bioavailability is 100%. It is evenly distributed in tissues, penetrates into smooth muscle cells. The time to reach the maximum concentration in the blood is 2 hours. The connection with plasma proteins is 95-98%. It is mainly excreted by the kidneys, to a lesser extent - with bile. Does not penetrate the blood-brain barrier.

Indications for use

Spasm of smooth muscles of the urinary and biliary organs (renal colic, pyelitis, tenesmus, biliary colic, intestinal colic, hyperkinetic dyskinesia of the biliary tract and gallbladder, cholecystitis, postcholecystectomy syndrome).

Spasm of smooth muscles of the gastrointestinal tract (usually as part of combination therapy): pylorospasm, gastroduodenitis, gastric ulcer and duodenal ulcer, spastic constipation, spastic colitis, proctitis.

Tensor headache.

Dysmenorrhea, threatening miscarriage, threatening premature birth, postpartum contractions.

When carrying out some instrumental studies, cholecystography.

Contraindications

Hypersensitivity to the components of the drug, severe hepatic and renal failure, severe heart failure (low cardiac output), lactation period.

This dosage form not applicable to children under 3 years of age. Due to the presence of lactose monohydrate (milk sugar) in the preparation, its use is contraindicated in congenital lactose intolerance, lactase deficiency, glucose-galactose malabsorption.

Carefully

Drotaverin should be used with caution in arterial hypotension, severe atherosclerosis of the coronary arteries, prostatic hyperplasia, angle-closure glaucoma, during pregnancy.

Method of administration and dosage

Adults are prescribed orally 40-80 mg (1-2 tablets) 2-3 times a day. Maximum daily dose- 240 mg.

Children aged 3 to 6 years - in a single dose of 20 mg, the maximum daily dose is 120 mg (in 2-3 doses); at the age of 6 to 12 years, one-time - 40 mg, the maximum daily dose - 200 mg; frequency of application - 2-5 times a day.

Side effect

Dizziness, headache, insomnia, palpitations, decreased blood pressure, allergic reactions, nausea, constipation, fever, sweating.

Overdose

There are no data on overdose in relation to the drug.

Interaction with other medicinal products

With simultaneous use, it can weaken the antiparkinsonian effect of levodopa.
Enhances the action of papaverine, bendazole and other antispasmodics (including M-anticholinergics), lowering blood pressure caused by tricyclic antidepressants, quinidine and procainamide.
Reduces the spasmodic activity of morphine.
Phenobarbital increases the severity of the antispasmodic effect of drotaverine hydrochloride.

special instructions

In the treatment of gastric ulcer and duodenal ulcer used in combination with other medicines, usually prescribed for the treatment of this group of diseases of the esophagus, stomach and duodenum.

When taken orally in therapeutic doses, drotaverine does not affect the ability to drive and perform work that requires increased attention. If any side effects appear, the question of driving vehicles and working on machines requires individual consideration.

Release form

Tablets 40 mg. 10 tablets in a blister strip packaging.
1, 2, 3, 4 or 5 blisters together with instructions for use in a cardboard box.
There are 100 tablets in a polymer jar. Each can, along with instructions for use, is placed in a cardboard box.

Storage conditions

Store in a dry, dark place and out of reach of children, at a temperature not exceeding 25 ° C.

Shelf life

3 years. Do not use after the expiration date printed on the package.

Conditions of dispensing from pharmacies

"Drotaverin" is a well-known antispasmodic, which is often used by adults for cholecystitis, intestinal colic, urolithiasis and other problems, to get rid of which you need to eliminate the spasm of smooth muscles. Not everyone knows if such a medicine is used in childhood, when the medication is prescribed to children and how it affects the child's body.

Release form

Drotaverin is produced by:

• In pills which are taken internally. They are characterized by a yellow-greenish color and flat round shape... One pack contains from 10 to 100 tablets.
• In solution for injections. It is represented by a clear yellow or greenish-yellow liquid, poured into dark glass ampoules of 2 or 4 ml. One box sells 5, 10 or 20 ampoules.

In addition, the drug can be produced with a slightly changed name - for example, "Drotaverin-UBF", "Drotaverin-Ellara" or "Drotaverin-Teva". Moreover, such drugs include the same active compound, are also produced in tablets and solution, and the dosage of the active ingredient, as well as the indications, other features of use, they have the same. Additional letters or words in the title only indicate pharmaceutical company, which makes such a version of "Drotaverin".

Composition

Active ingredient any form of the drug is drotaverine hydrochloride. One tablet usually contains 40 mg of such a compound, but Drotaverin Forte is also available at a dosage of 80 mg per 1 tablet. One milliliter injection form may contain either 10 or 20 mg of the active ingredient.

Among the excipients in tablet form, you can see talc, potato starch, povidone, lactose monohydrate and other components (depending on the manufacturer). In addition to drotaverine and sterile water, sodium disulfite may be present in the injection solution, as well as ethanol, acetic acid, sodium metabisulfite or sodium acetate trihydrate.

Operating principle

Drotaverin has the ability to relax smooth muscles, which is located in the walls of blood vessels and in internal organs, so the medication eliminates spasms (which also helps to get rid of pain caused by spasms) and dilates blood vessels, while lowering blood pressure.

The drug is most effective on smooth muscles in the gastrointestinal tract, genitourinary organs, and biliary tract. This leads to a decrease painful sensations and discomfort caused by increased tone or spasm in such organs. "Drotaverin" is considered an effective pain reliever for different functional disorders and diseases of the gastrointestinal tract, gallbladder, Bladder and kidneys.

Due to the vasodilating effect of the drug, microcirculation improves, that is, more nutrients and oxygen are supplied to the tissue. Since "Drotaverin" does not have a sedative effect, it can be used in situations where M-anticholinergic antagonists cannot be given (for example, in case of glaucoma in a closed-angle form).

Indications

"Drotaverin" is prescribed both in the presence of pain and functional disorders in the work of internal organs due to spasm of smooth muscles, and in order to prevent such problems.

The medicine is used:

• For abdominal pain caused by spastic constipation, gastritis, pylorospasm, intestinal colic, enteritis, flatulence and other lesions of the gastrointestinal tract.
• With hepatic colic, biliary dyskinesia, cholangitis and other diseases of the biliary tract.
• With cystitis, bladder spasms, pyelitis, renal colic and other pathologies of the urinary system.
• For headaches.
• With vasospasm (at high temperature).
• During examinations, during which a medical instrument is inserted into the body (for example, during gastroscopy).
• With a strong dry cough caused by bronchospasm or laryngotracheitis. Although this indication is not noted in the official instructions, many doctors note the effect of "Drotaverin" on the bronchi, therefore they recommend drinking the drug at night so that the child does not suffer from coughing and sleeps peacefully.

The injectable form of the drug is prescribed in exceptional cases and only in an acute condition, in order to help the child as soon as possible. As soon as the spasm is removed, they switch to the use of pills. In addition, Drotaverin injections are prescribed when it is impossible to give pills to a small patient.

From what age is it allowed to take?

Drotaverin tablets are prescribed from the age of 3, and injections are prescribed to children over 1 year of age. Age restrictions in the use of the tablet form are associated only with the difficulties of children under 3 years of age with swallowing solid medicine. If the baby knows how to swallow a pill, this form can be used at the age of over a year.

Contraindications

The medicine is not prescribed:

• With individual sensitivity to any component of the solution or tablets.
• With severe renal failure.
• With heart failure.
• With serious liver pathologies.
• With hypotension.
• With atrioventricular block.

If the child has angle-closure glaucoma, the use should be monitored by a doctor. For adults, the drug is not prescribed for breastfeeding and in the first trimester of pregnancy.

Side effects

When treating with "Drotaverin", the appearance of insomnia, dizziness, nausea, arrhythmias, increased sweating, decreased blood pressure, vomiting, allergic reaction, feelings of fever, constipation and other negative symptoms. When they appear, you should immediately tell your doctor about such reactions.

Instructions for use and dosage

Pills

The drug in this form is taken after meals. The medication should be swallowed whole, without chewing or crushing into powder. To wash down the medicine, use a small amount of clean water.

The dose of such a remedy depends on the age of the little patient:

• A child 3-6 years old (for example, at 4 years old) is given 1 / 4-1 / 2 tablets (10-20 mg "Drotaverin"). Taking the drug in this dosage is prescribed twice or three times a day, and maximum dose for a child 5 years old and other babies of this age is 3 tablets (120 mg of active compound).
• A child of 6-12 years old is prescribed from 20 to 40 mg of "Drotaverin" at one time, which corresponds to half or a whole tablet. The drug is given from two to five times a day, and the acceptable maximum is called 5 tablets (200 mg "Drotaverin").
• A teenager over the age of 12 is given 40-80 mg of "Drotaverin" (1-2 tablets) for 1 dose. The drug is taken 2-3 times a day, and the maximum dose at this age is 6 tablets (240 mg of the active ingredient).

The duration of treatment with pills usually does not exceed 1-2 weeks and is determined by the doctor individually.

Injections

Drotaverine injections can be injected into a muscle, into a vein, or under the skin. For colic, the solution is most often administered intravenously. If the patient has a peripheral vasospasm, the drug can be injected into the artery as well. In other cases, subcutaneous and intramuscular injections are used.

The drug is administered 1-3 times a day. The dose of the medication, as for tablets, is determined by age:

• A child 1 year old, 2 years old and older (up to 6 years old) take 0.5-1 ml of medicine for one injection, because single dose for this age is 10-20 mg of "Drotaverin".
• Children 6-12 years old are prescribed 20 mg of active compound per dose, which corresponds to 1 ml of solution.
• For a child over 12 years old, 1-2 ampoules of the drug are taken for one injection.

The maximum daily dosage of the drug is the same as for the tablet form. With an intravenous injection, the child must be lying down so that the injection does not cause a collapse. The ampoule for such injections is diluted with glucose or saline solution (10-20 ml), and the injection itself is performed very slowly. For injections under the skin or into muscle tissue, it is not necessary to dilute Drotaverin.

Overdose

If the dose of the medication is exceeded, it will negatively affect the work of the heart and may interfere with breathing. In such a situation, you should immediately consult a doctor.

Interaction with other drugs

Drotaverin has the ability to enhance therapeutic effect others antispasmodics and weaken the effect of levodopa. When used together with Phenobarbital, the antispasmodic effect of Drotaverin is enhanced.

At elevated temperature"Drotaverin" is often included in the composition of the lytic mixture, which includes "Analgin" (it can be replaced by "Paracetamol") and "Diphenhydramine" (or "Suprastin"). In this combination, the drugs effectively fight white fever.

Terms of sale

Drotaverin tablets are non-prescription drugs, and you need a doctor's prescription to buy ampoules.

Storage conditions and shelf life

To store the medicine, a dry place hidden from sunlight is required, where the temperature will not exceed +25 degrees. You need to keep the drug at home where a small child cannot get it. The shelf life of both tablets and solution is 3 years.