The positive effects of quercetin on the human body. What products contain the most, the ability to buy supplements on iHerb. Quercetin - description of the drug, instructions for use, reviews What is quercetin and how is it useful
This agent belongs to pro-glassy, \u200b\u200bradio- and cardioprotective, capillary-stabilizing and regenerative medicinesthat have anti-inflammatory, antioxidant, antispasmodic, diuretic, antiulcerogenic, anti-sclerotic properties.
Release form
Granule sachets, weighing two grams.
Indications for use
Quercetin is used according to instructions by adults and children over twelve years of age for the purpose of prevention and treatment in case of radiation injury after gamma and X-ray radiation therapy, treatment of erosive and ulcerative diseases of the mucous membrane oral cavity, periodontal disease, with inflammatory and purulent diseases in soft tissues, if necessary, complex treatment of vertebral pain and climacteric syndrome, chronic glomerulonephritis, neuroreflex signs of osteochondrosis of the spine, as well as to prevent erosive and ulcerative lesions in the upper alimentary canal, which have arisen due to the use of anti-inflammatory drugs. Quercetin is also used in the treatment of exertional angina II - III FC, ischemic disease heart, neurocirculatory dystonia.
Method of administration and dosage
When used topically, two grams of Quercetin must be dissolved in hot water, in 10 ml, or one gram of Quercetin in 5 ml of hot water. Then you need to mix everything thoroughly until a consistency resembling a gel is formed. If a patient has erosive and ulcerative diseases of the oral mucosa and periodontal disease, then he needs to do an application every day using this gel, previously applied to napkins.
Quercetin is also prescribed according to the instructions and to patients living in areas that are contaminated with radionuclides. In this case, the drug for adults and children over twelve years of age must be taken orally one gram at a time, this is half a teaspoon, twice a day. It is recommended to use Quercetin half an hour before a meal, adding half a glass of water to the granules. Only a doctor can determine the duration of the course.
Quercetin is prescribed in case complex therapy purulent-inflammatory diseases of soft tissues internally and locally in the same amount. That is, inside - 1 gram per half a glass of water, topically - 2 grams per 10 ml of hot water, twice a day.
The drug is prescribed locally and internally for the prevention and treatment of local lesions in the case of radiation sickness. Apply the gel to the damaged parts of the body two to three times a day. Reviews of Quercetin are only positive.
Usually, according to the instructions, Quercetin is administered orally to adults and children over twelve years of age, 1 gram three to four times a day. For this purpose, half a teaspoon of Quercetin must be added to half a glass of water and infused. Should be taken half an hour before meals. The duration of treatment must be determined by the doctor. The drug is prescribed in the amount of three grams per day for chronic glomerulonephritis, neuroreflex manifestations of osteochondrosis of the spine, coronary heart disease, vertebral pain syndrome and to prevent the ulcerogenic effect of non-steroidal anti-inflammatory drugs.
When combined with non-steroidal anti-inflammatory drugs, the drug Quercetin is used in an amount of six grams three times a day - two grams each, to prevent stomach ulcers.
Assign Quercetin granules to adolescents suffering from neurocirculatory dystonia, two grams of Quercetin granules twice a day for one month.
Side effects of Quercetin
An increased individual sensitivity may appear, this is most often expressed in the occurrence of a rash, itching. If at least some unusual reactions are detected, you need to stop using the drug Quercetin and immediately consult a doctor to consult him on this matter.
Contraindications
Allergy to the components contained in the preparation.
Application during pregnancy
Quercetin is non-toxic, but should not be used during pregnancy. Especially when it comes to the first trimester of pregnancy. According to reviews of Quercetin, it is also not worth taking the drug during lactation.
Interaction with other drugs
By combining Quercetin with ascorbic acid preparations, an increase in the effects can be observed. This is evidenced by numerous reviews of Quercetin.
the flavonoid quercetin is an aglycone of many plant flavonoid glycosides, including rutin, and belongs to vitamin preparations group R. Due to capillary stabilizing properties associated with antioxidant, membrane stabilizing effects, the drug reduces capillary permeability. Quercetin has an anti-inflammatory effect as a result of blocking the lipoxygenase pathway of arachidonic acid metabolism, reduces the synthesis of leukotrienes, serotonin and other inflammatory mediators.
Quercetin exhibits anti-ulcer action associated with the use of anti-inflammatory drugs, and also has a radioprotective activity (after X-ray and gamma irradiation).
The cardioprotective properties of Quercetin are due to an increase in the energy supply of cardiomyocytes due to its antioxidant effect and an improvement in blood circulation.
The regenerative properties of Quercetin are manifested in accelerated wound healing. The drug can affect the processes of bone tissue remodeling; it exhibits persistent immunomodulatory activity.
Diuretic, antispasmodic, antisclerotic properties were also experimentally determined. Quercetin is able to normalize blood pressure and stimulate the release of insulin, accelerate platelet aggregation, and inhibit thromboxane synthesis.
Quercetin also binds to estrogen receptors. Due to estrogen-like properties (influence on proline hydroxylase, inhibition of tumor necrosis factor and synthesis of interleukins), the drug has a proosteoclastic effect.
After oral administration, the drug is well absorbed. Further pharmacokinetics of the drug have not been studied.
Indications for use of the drug Quercetin
Prevention of erosive and ulcerative lesions of the upper digestive tract caused by taking NSAIDs.
In complex treatment:
- local radiation injuries after X-ray and gamma-irradiation therapy, as well as for their prevention;
- periodontal disease, erosive and ulcerative diseases of the oral mucosa; - purulent-inflammatory diseases of soft tissues;
- climacteric, vertebral pain syndrome, neuroreflex manifestations of osteochondrosis of the spine;
- chronic glomerulonephritis;
- neurocirculatory dystonia, ischemic heart disease, exertional angina II - III FC.
Application of the drug Quercetin
Quercetin granules are prescribed for both local and oral administration in adults and children over 12 years of age.
For local application:
2 g of Quercetin granules are dissolved in 10 ml of water at a temperature of 45-50 ° C until a homogeneous viscous mass (gel) is formed.
For oral administration: 1 g (1/2 teaspoon) of Quetsetin granules is dissolved in 100 ml of warm water.
With periodontal disease and erosive and ulcerative diseases of the oral mucosa make one application daily with a gel, which is previously applied to a sterile napkin.
In the complex therapy of purulent-inflammatory diseases of soft tissues Quercetin is prescribed locally and internally in the same doses: locally - application of a gel of 2 g of Quercetin granules 2 times a day, inside - 1 g (1/2 teaspoon) of granules 2 times a day.
For the prevention and treatment of local lesions in radiation sickness the drug is prescribed topically and internally. Gel applications are applied to damaged areas of the body 2-3 times a day. Inside appoint 1 g 3-4 times a day 30 minutes before meals. For patients living in areas contaminated with radionuclides, Quercetin is prescribed orally 1 g (1/2 teaspoon) of granules 2 times a day 30 minutes before meals.
In complex treatment neuroreflex manifestations of spinal osteochondrosis, chronic glomerulonephritis, ischemic heart disease, as well as to prevent the ulcerogenic action of NSAIDs the drug is administered orally at a dose of 1 g per dose 3 times a day. With simultaneous use with NSAIDs, adults can use Quercetin orally in a dose of 2 g per dose 3 times a day.
When neurocirculatory dystonia the drug is administered orally 2 g of Quercetin granules 2 times a day for a month.
IN complex treatment climacteric, vertebral pain syndrome include taking granules of Quercetin 1 g 3 times a day. The treatment period is 6 months.
Contraindications to the use of the drug Quercetin
Hypersensitivity to quercetin and drugs with P-vitamin activity; childhood up to 12 years old.
Side effects of the drug Quercetin
Possible manifestations of increased individual sensitivity - rash, itching.
Special instructions for the use of the drug Quercetin
Use during pregnancy and lactation.
It is not recommended to use the drug during pregnancy or lactation. In the case of prescribing the drug to women during lactation, feeding should be stopped for the period of treatment.
Children. There is no experience of using Quercetin in children under the age of 12, therefore it is not recommended to use the drug in this age group.
The ability to influence the reaction rate when driving or operating other mechanisms. Does not affect.
Drug interactions Quercetin
When using Quercetin with ascorbic acid preparations, the effects are summed up. When the drug is combined with NSAIDs, the anti-inflammatory effect of the latter is enhanced.
Overdose of the drug Quercetin, symptoms and treatment
When long-term use possible manifestations of hypersensitivity to the drug in the form allergic reactions... Treatment is symptomatic.
Storage conditions of the drug Quercetin
In a dry, dark place at a temperature not exceeding 25 ° C.
List of pharmacies where you can buy Quercetin:
- St. Petersburg
Attention! The information is provided for informational purposes only. This instruction should not be used as a guide to self-medication. The need for prescription, methods and doses of the drug are determined exclusively by the attending physician.
general characteristics
chemical name: 2- (3,4-dihydroxyphenyl) -3,5,7-trihydroxy-4H-1-benzopyran-4-one dihydrate;
basic physical and chemical properties: granules of yellow color with a greenish tinge;
composition: 100 g of granules contains 4 g of quercetin;
excipients: apple pectin, glucose (Glucose - grape sugar, a carbohydrate from the group of monosaccharides. One of the key metabolic products that provides living cells with energy), sugar.
Release form. Granules.
Pharmacotherapeutic group
Capillary stabilizing agents. ATC code С05С Х02 **.
Pharmacological properties
Pharmacodynamics... The flavonoid quercetin is aglycone (Aglycon - a non-carbohydrate fragment of glycosides. Aglycone in most cases determines the biological activity of glycosides (pharmacodynamic properties)) many plant flavonoid glycosides (Glycosides - organic substances, the molecules of which consist of a carbohydrate and a non-carbohydrate component (aglycone). Widespread in plants, where they can be a form of transport and storage of various substances), including rutin, and belongs to group P vitamin preparations. Due to the capillary-stabilizing properties associated with antioxidant, membrane-stabilizing effects, the drug reduces permeability capillaries (Capillaries - the smallest vessels that penetrate organs and tissues. Connect arterioles with venules (the smallest veins) and close the circle of blood circulation)... Quercetin has anti-inflammatory effects as a result blockades (Blockade - slowing down or interruption of electrical impulses in any part of the conducting system of the heart or myocardium) lipoxygenase pathway metabolism (Metabolism - the totality of all types of transformations of substances and energy in the body, ensuring its development, vital activity and self-reproduction, as well as its connection with the environment and adaptation to changes in external conditions) arachidonic acid, reduces the synthesis of leukotrienes, serotonin (Serotonin - a derivative of the amino acid tryptophan. Synthesized primarily in the central nervous system and chromaffin cells gastrointestinal tract... Conduction mediator nerve impulse through the synapse. Vertebrate brain neurons that use serotonin as a mediator are involved in the regulation of many forms of behavior, sleep processes, thermoregulation, etc. As a hormone, serotonin also regulates gastrointestinal tract motility, mucus secretion, causes spasm of damaged vessels, etc. ) and others mediators (Mediator - a substance that transfers excitation from a nerve ending to a working organ and from one nerve cell to another) inflammation.
Quercetin exhibits antiulcerogenic action associated with the use of anti-inflammatory drugs, and also has a radioprotective activity (after X-ray and gamma irradiation).
The cardioprotective properties of Quercetin are due to an increase in the energy supply of cardiomyocytes due to its antioxidant effect and an improvement in blood circulation.
The regenerative properties of Quercetin are manifested in accelerated wound healing. The drug can affect the processes of bone tissue remodeling; it exhibits persistent immunomodulatory activity.
Diuretic, antispasmodic, antisclerotic properties were also experimentally determined. Quercetin is able to normalize blood pressure and stimulate the release of insulin, accelerate aggregation (Aggregation (attachment) - the process of combining elements into one system) platelets (Platelets - blood cells involved in the process of blood clotting. With a decrease in their number - thrombocytopenia - there is a tendency to bleeding), inhibit the synthesis of thromboxane.
Quercetin also binds to receptors (Receptor (Latin receptio - perception, English receptor): 1) specific sensitive formations in living organisms that perceive external and internal stimuli (extero- and interoreceptors, respectively) and transform activity nervous system... Depending on the type of perceived irritation, mechanoreceptors, chemoreceptors, photoreceptors, electroreceptors, thermoreceptors are distinguished; 2) active groups of protein macromolecules with which mediators or hormones specifically interact, as well as many drugs. A receptor is a conformationally flexible macromolecule or a set of macromolecules, binding to which (s) a ligand (agonist or antagonist) causes a biological or pharmacological effects... A number of receptors exist in several subtypes. There are four main types of receptors: 1) membrane receptors associated with ion channels and consisting of several protein subunits, which are located in biological membranes of cells in a radial order, forming ion channels (for example, H-cholinergic receptors, GABA A-receptors, glutamate receptors ) \\; 2) membrane receptors conjugated with G-proteins, consisting of protein molecules, sevenfold "stitching" biological membranes; biological effect when these receptors are activated, it develops with the participation of a system of secondary transmitters (Ca2 + ions, cAMP, inositol-1,4,5-triphosphate, diacylglycerol). Receptors of this type are available for a number of hormones and mediators (for example, M-cholinergic receptors, adrenergic receptors, etc.) \\; 3) intracellular, or nuclear receptors that regulate the processes of DNA transcription and, accordingly, the synthesis of proteins by cells. They are cytosolic and nuclear proteins (for example, receptors for steroid and thyroid hormones) \\; 4) membrane receptors that directly control the functions of the effector enzyme associated with tyrosine kinase and regulate the phosphorylation of proteins (for example, insulin receptors, a number of growth factors, etc.)) estrogen (Estrogen - the pituitary hormone responsible for the maturation of eggs)... Due to estrogen-like properties, (effect on proline hydroxylase, inhibition of tumor necrosis factor and synthesis interleukins (Interleukins - one of the groups of cytokines, are polypeptide mediators involved in the formation and regulation of local defense reactions organism)) the drug has proosteoclastic effects.
Pharmacokinetics... Not studied. The drug is well absorbed.
Indications for use
Prevention and treatment of local radiation injuries after X-ray and gamma-irradiation therapy (Therapy - 1. The field of medicine studying internal illnesses, one of the oldest and most basic medical specialties. 2. Part of a word or phrase used to designate the type of treatment (oxygen therapy \\; hemotherapy - treatment with blood preparations)); treatment of periodontal disease, erosive and ulcerative diseases of the oral mucosa; purulent-inflammatory diseases of soft tissues; in the complex treatment of menopause, vertebrally (Vertebral - vertebral, related to the vertebrae)-pain syndrome (Pain syndrome - a painful subjective sensation that appears due to the effect on the body of superstrong or destructive stimuli. Distinguish pain syndromes of the head, face, mouth, back, etc.), neuroreflex manifestations of spinal osteochondrosis; chronic (Chronic - a long, incessant, protracted process, proceeding either constantly or with periodic improvements in the condition) glomerulonephritis (Glomerulonephritis - kidney disease, characterized by bilateral autoimmune inflammatory changes in the glomeruli); to prevent erosive and ulcerative lesions of the upper alimentary canal, caused by the intake of non-steroidal anti-inflammatory drugs. The drug is used for neurocirculatory dystonia (Cardiopsychoneurosis - syndrome functional disorders activity of the cardiovascular system, manifested by cardiovascular, respiratory and vegetative disorders, asthenia, poor tolerance to stress and physical exertion. The disease flows in waves, with periods of exacerbations and remissions, has a favorable prognosis), ischemic heart disease (Coronary artery disease - a chronic pathological process, which is caused by insufficient blood supply to the myocardium. Most cases (97–98%) are the result of atherosclerosis coronary arteries hearts. The main clinical forms are angina pectoris, myocardial infarction and coronary (atherosclerotic) cardiosclerosis), angina pectoris (Angina pectoris - a syndrome caused by myocardial ischemia and characterized by the episodic appearance of a feeling of discomfort or pressure in the precordial region, which in typical cases occurs with physical activity and disappear after stopping it or taking nitroglycerin under the tongue (exertional angina)) voltage ІІ - ІІІ FC.
Method of administration and dosage
For topical application, 2 g of Quercetin granules are dissolved in 10 ml of hot water (or 1 g in 5 ml) and infused until a gel is obtained. In case of periodontal disease and erosive and ulcerative diseases of the oral mucosa, one application is made daily with a gel, which is previously applied to sterile napkins.
For patients living in areas contaminated with radionuclides, Quercetin is prescribed internally for adults and children over 12 years of age, 1 g (1/2 teaspoon) 2 times a day. It is recommended to take quercetin 30 minutes before meals, after adding ½ glass of water to the granules.
In the complex therapy of purulent-inflammatory diseases of soft tissues, Quercetin is prescribed for adults and children over 12 years old locally and internally in the same doses: locally - 2 g of Quercetin granules in 10 ml of hot water (or 1 g in 5 ml), internally - 1 g each (1/2 teaspoon) adding 1/2 cup of water to the granules, 2 times a day.
For the prevention and treatment of local lesions with radiation sickness, the drug is prescribed locally and internally. Gel applications are applied to damaged parts of the body 2-3 times a day. Inside appoint adults and children over 12 years of age 1 g 3-4 times a day. To do this, 1/2 teaspoon of Quercetin granules (1 g) is added to 1/2 glass of water, insisted and taken 30 minutes before meals.
For adults with neuroreflex manifestations of osteochondrosis of the spine, chronic glomerulonephritis, ischemic heart disease, as well as to prevent ulcerogenic (Ulcerogenic - causing an ulcer) the action of non-steroidal anti-inflammatory drugs, the drug is prescribed at a dose of 3 g per day, divided into three doses.
When used simultaneously with non-steroidal anti-inflammatory drugs, adults can be used in a dose of 6 g (3 times a day, 2 g) to prevent manifestations peptic ulcer stomach.
Adolescents with neurocirculatory dystonia (Dystonia - widespread in medical practice, the designation of disorders of various origins and manifestations caused by a violation neurohumoral regulation vegetative functions), appoint 2.0 g of Quercetin granules twice a day for a month.
For the treatment of women in the pre- and postmenopausal period with vertebral pain syndrome in the complex treatment include granules of Quercetin 1.0 g three times a day. The treatment period is 6 months.
Overdose
With prolonged use, manifestations of hypersensitivity to the drug are possible in the form of allergic reactions that require symptomatic therapy.
Side effect
Possible manifestations of increased individual sensitivity, rash, itching.
Contraindications
Hypersensitivity to quercetin and drugs with P-vitamin activity.
Application features
Although Quercetin is a practically non-toxic drug, it is undesirable to use it during pregnancy, especially in the first trimester; during lactation (Lactation - milk secretion by the mammary gland) taking the drug is also not recommended. Data clinical trials (Clinical trial - study of the safety and / or efficacy of the investigational drug in humans to identify or confirm its clinical, pharmacological, pharmacodynamic properties, side effects and / or to study its absorption, distribution, biotransformation and excretion) children under 12 years old do not.
Interaction with other medicinal products
When using Quercetin with ascorbic acid preparations, the effects are summed up.
When the drug is combined with non-steroidal anti-inflammatory drugs, the anti-inflammatory effect is enhanced.
General product information
Conditions and shelf life. Keep out of reach of children, dry, protected from light at a temperature not exceeding 25 ° C.
Shelf life is 2 years.
Vacation conditions. Without recipe.
Packaging. Granules in bags of 2 g.
Manufacturer.CJSC SPC "Borshagovskiy Chemical-Pharmaceutical Plant".
Location.03680, Ukraine, Kiev, st. Mira, 17.
Site.www.bhfz.com.ua
This material is presented in free form based on the official instructions for medical use drug.
This substance is a flavonoid that prevents aging of cells of the epidermis, so anyone who wants to keep the skin youthful will not be superfluous to find out where the most quercetin is contained and what foods need to be included in their diet to saturate the body with it.
What foods contain quercetin?
The leading positions in the list of products containing quercetin are held by buckwheat, black and lovage, apples and capers. It is in them that you will find a large amount of this substance, so experts recommend using them regularly, for example, replacing coffee with a cup of tea, or eating at least one apple a day.
It will be equally useful to add to daily menu grapes, red onions, broccoli, different varieties of tomatoes and leafy vegetables are also among the foods that contain this flavonoid. Do not forget that the older a person gets, the more he needs qurecetin to maintain normal skin turgor, focusing on this rule, and the daily intake of this substance should be calculated. That is, at 20-25 years old, it is enough to eat 1 apple or a portion of lettuce with tomatoes per day, and at 35-40 years old it will not be superfluous to add the same grapes to this, using it at least 1-2 times in 10-12 days.
Cranberries, blueberries, and rowan berries - this is what else quercetin contains in a fairly large amount. Therefore, in the fall and summer, do not be too lazy to buy or pick these berries on your own, eating only 100-150 g of them, you will get almost the daily rate of this flavonoid.
The benefits of quercetinIn addition to slowing down the aging process of skin cells, this substance helps to reduce the level, so it will be useful to eat foods with it for men and women over 35-40 years old who are at risk. It is equally important to get the right amount of this flavonoid for those who are actively involved in sports, since the substance helps to restore joint tissues, saving a person from developing a disease such as arthritis.
Quercetin will bring undoubted benefits to those who are trying to take care of the condition of their blood vessels, as it strengthens their walls, makes them more elastic.
Summing up, it can be noted that those who want to maintain youth, well-being and vigor for many years should review their diet, and add the above-mentioned foods that contain a large amount of quercetin to it, this will be a really smart decision.
Instructions
for medical use
Quercetin
Tradename
Quercetin
International non-proprietary name
Dosage form
Granules 2 g
Composition
1 g of granules contains
active substance -quercetin (in terms of 100% dry matter) 0.04 g,
excipients:apple pectin, glucose monohydrate, sugar.
Description
Granules of yellow color with a greenish tinge.
Pharmacotherapeuticeskaya Group
Angioprotectors. Drugs that reduce capillary permeability. Other drugs that reduce capillary permeability.
ATX code С05С X
Pharmacological properties
Pharmacokinetics
The drug is well absorbed. Other pharmacokinetic parameters have not been studied.
Pharmacodynamics
The flavonoid quercetin is a non-carbohydrate biodegradable active ingredient of many plant flavonoid glycosides, including rutin, and belongs to the vitamin P group. Due to the capillary stabilizing properties associated with the antioxidant, membrane stabilizing effect, the drug reduces capillary permeability. Quercetin has an anti-inflammatory effect as a result of blocking the lipoxygenase pathway of arachidonic acid metabolism, reduces the synthesis of leukotrienes, serotonin and other inflammatory mediators.
Quercetin exhibits anti-ulcer action associated with the use of anti-inflammatory drugs, and also has a radioprotective activity (after X-ray and gamma irradiation).
The cardioprotective properties of Quercetin are due to an increase in the energy supply of cardiomyocytes due to its antioxidant effect and an improvement in blood circulation.
The reparative properties of Quercetin are manifested in accelerated wound healing. The drug can affect the processes of bone tissue remodeling; it exhibits persistent immunomodulatory activity.
Diuretic, antispasmodic, antisclerotic properties were also experimentally determined. Quercetin is able to normalize blood pressure and stimulate the release of insulin, accelerate platelet aggregation, and inhibit thromboxane synthesis.
Quercetin also binds to estrogen receptors. Due to estrogen-like properties (effect on proline hydroxylase, suppression of tumor necrosis factor and synthesis of interleukins), the drug has proosteoclastic effects.
Indications for use
Prevention of erosive and ulcerative lesions of the upper alimentary canal caused by the intake of non-steroidal anti-inflammatory drugs
as part of combination therapy
Local radiation injuries after X-ray and gamma-irradiation therapy, as well as for their prevention
Erosive and ulcerative diseases of the oral mucosa, periodontal disease
Purulent-inflammatory diseases of soft tissues
Climacteric syndrome
Vertebral pain syndrome
Neuroreflex manifestations of osteochondrosis
Chronic glomerulonephritis
Neurocirculatory dystonia
Ischemic heart disease and exertional angina II-III functional class
Method of administration and dosage
Quercetin is used for topical and internal use... Assign to adults.
For topical application: 2 g of Quercetin granules are dissolved in 10 ml of water at a temperature of 45-50 ºС until a homogeneous viscous mass (gel) is formed.
For internal use:1 g (1/2 teaspoon) of Quetsetin granules is dissolved in 100 ml of warm water.
When periodontal disease and erosive and ulcerative diseases of the oral mucosa make one application daily with a gel, which is previously applied to a sterile napkin.
In the complex therapy of purulent-inflammatory diseases of soft tissues Quercetin is prescribed locally and internally in the same doses: locally - application of a gel of 2 g of Quercetin granules 2 times a day, inside - 1 g (1/2 teaspoon) of granules 2 times a day.
For prevention and treatment of local lesions in radiation sickness the drug is prescribed topically and internally. Gel applications are applied to damaged areas of the body 2 to 3 times a day. Inside appoint 1 g 3-4 times a day 30 minutes before meals. For patients living in areas contaminated with radionuclides, Quercetin is prescribed orally 1 g (1/2 teaspoon) of granules 2 times a day 30 minutes before meals.
In complex treatment neuroreflex manifestations of spinal osteochondrosis, chronic glomerulonephritis, ischemic heart disease, and to prevent ulcerogenic action of non-steroidal anti-inflammatory drugs the drug is administered orally at a dose of 1 g per reception 3 times a day. With simultaneous use with non-steroidal anti-inflammatory drugs for adults, it is possible to use Quercetin orally at a dose of 2 g per dose 3 times a day.
When neurocirculatory dystonia the drug is administered orally 2 g of Quercetin granules twice a day for a month.
Complex treatment climacteric, vertebral pain syndrome include the intake of granules of Quercetin 1 g 3 times a day. The treatment period is 6 months.
Side effects
Allergic reactions (rash, itchy skin, Quincke's edema)
Dry mouth, nausea
Headache, tingling sensation in the fingers
Moderate hypotension.
Contraindications
Hypersensitivity to quercetin, drugs with P-vitamin activity and / or other components of the drug
Severe arterial hypotension
Pregnancy and lactation
Children and adolescents up to 18 years old.
Drug interactions
When joint application Quercetin:
Summation of effects is observed with preparations of ascorbic acid;
With non-steroidal anti-inflammatory drugs, the anti-inflammatory effect of the latter is enhanced;
With organic nitrates, quercetin can cause arterial hypotension;
With fibrinolytics, quercetin leads to an increase in the effectiveness of thrombolytic therapy;
With digoxin, the maximum serum concentration and the total area under the concentration-time curve of digoxin increase;
Cyclosporine increases the bioavailability and blood concentration of cyclosporine;
With paclitaxel, there is an effect on the metabolism of the latter;
With verapamil, the bioavailability of the latter increases;
With tamoxifen, bioavailability increases, metabolism and excretion of the latter decreases.
special instructions
With prolonged use, manifestations of hypersensitivity to the drug in the form of allergic reactions are possible.
Since the drug contains sucrose and glucose, patients with hereditary fructose intolerance, glucose-galactose malabsorption syndrome, sucrose-isomaltose should not be used.
Application in pediatrics
No experience clinical use the drug in children and adolescents under 18 years of age.
Features of the effect of the drug on the ability to manage vehicle or potentially dangerous mechanisms
There is no data on the effect of the drug on the patient's ability to drive a vehicle or potentially dangerous machinery.
Overdose
Symptoms:rash, itchy skin.
Treatment:drug withdrawal; carrying out desensitizing therapy.
Release form and packaging
