Bromhexine tablets and syrup for children: instructions for use and what it is for, price, reviews. Bromhexin: instructions for use, analogs and reviews, prices in pharmacies in Russia Bromhexin tablets contraindications
Name:
Bromhexin (Bromhexin)
Pharmacological
action:
Mucolytic agent with expectorant action.
Reduces the viscosity of bronchial secretions by depolarizing the acidic polysaccharides contained in it and stimulating the secretory cells of the bronchial mucosa, which produce secretions containing neutral polysaccharides.
It is believed that bromhexine promotes the formation of a surfactant.
Pharmacokinetics
Bromhexine is rapidly absorbed from the gastrointestinal tract and undergoes intensive metabolism during the "first pass" through the liver. Bioavailability is about 20%. In healthy patients, Cmax in plasma is determined after 1 hour.
It is widely distributed in body tissues. About 85-90% is excreted in the urine mainly in the form of metabolites. The metabolite of bromhexine is ambroxol.
Plasma protein binding of bromhexine is high. T1 / 2 in the terminal phase is about 12 hours.
Bromhexine penetrates the BBB. In small quantities, it crosses the placental barrier.
Only small amounts are excreted in the urine with a T1 / 2 6.5 h.
The clearance of bromhexine or its metabolites may decrease in patients with severe hepatic and renal impairment.
Indications for
application:
Bronchopulmonary diseases, accompanied by the formation of high-viscosity sputum:
- bronchial asthma;
- cystic fibrosis;
- pulmonary tuberculosis;
- pneumonia;
- tracheobronchitis;
- obstructive bronchitis;
- bronchiectasis;
- emphysema of the lungs;
- pneumoconiosis.
Mode of application:
Take bromhexine inside(regardless of the reception, write) in the form of tablets.
Doses for adults - 0.016 g (16 mg = 2 tablets of 0.008 mg) 3-4 times a day; for children from 3 to 4 years old - 0.002 g (2 mg), from 5 to 14 years old - 0.004 g (4 mg) 3 times a day; children under 3 years of age are not prescribed the drug.
The effect of the drug begins to manifest itself usually 24-48 hours after the start of treatment. The course of treatment is from 4 days to 4 weeks.
For inhalation use solution should be diluted 1: 1 with distilled water and heated to body temperature to prevent coughing. In sick bronchial asthma or asmatic bronchitis before inhalation, you should take a bronchodilator (an agent that expands the lumen of the bronchi). Inhalation is carried out twice a day for adults, 4 ml, for children over 10 years old - 2 ml each, children aged 6 to 10 years old - 1 ml each, children aged 2 to years old - 10 drops each and children under 2 years old - each 5 drops for inhalation.
Parenteral(bypassing the digestive tract) introduction the drug is recommended for treatment in severe cases, as well as in postoperative period to prevent the accumulation of thick phlegm in the bronchi. 1 ampoule is administered subcutaneously, intramuscularly or intravenously 2-3 times a day slowly for 2-3 minutes.
Intravenously the drug is administered together with glucose or saline.
The drug is incompatible with alkaline solutions.
If necessary, bromtexin is prescribed simultaneously with antibacterial, bronchodilator, cardiac and other agents.
In the course of treatment, it is recommended to consume a sufficient amount of liquid, which supports the secretolytic effect of Bromhexine.
In children, treatment should be combined with postural drainage or vibration massage chest, facilitating the evacuation of secretions from the bronchi.
From the side digestive system
: dyspeptic phenomena, transient increase in the activity of hepatic transaminases in the blood serum.
From the side of the central nervous system: headache, dizziness.
Dermatological reactions: increased sweating, skin rash.
From the respiratory system: cough, bronchospasm.
Contraindications:
Age up to 3 years;
- I trimester of pregnancy;
- hypersensitivity to bromhexine.
At peptic ulcer stomach, as well as when indications of stomach bleeding a history of Bromhexine should be used under medical supervision.
Carefully use in patients with bronchial asthma.
Interaction
other medicinal
by means of:
Bromhexine can be administered in combination with bronchodilators, antibacterial drugs, drugs used in cardiology, and other drugs.
Incompatible with alkaline solutions.
Bromhexine is not used simultaneously with drugs containing codeine, because this makes it difficult to cough up the liquefied sputum.
Used as part of combination drugs vegetable origin with essential oils(including with eucalyptus oil, anise oil, peppermint oil, menthol).
Pregnancy:
During pregnancy and lactation, Bromhexine is used in cases where the intended benefit to the mother outweighs the potential risk to the fetus or child.
Overdose:
Symptoms: increased side reactions.
Treatment: artificial vomiting, fluid intake (milk or water) in the first 1-2 hours after administration, symptomatic therapy.
Release form:
1 tablet of Bromhexine contains:
- active substance: bromhexine hydrochloride - 8 mg;
- excipients: sugar, lactose monohydrate, potato starch, stearic acid, microcrystalline cellulose.
V 5 ml Bromhexine syrup contains:
- active substance: bromhexine hydrochloride - 4 mg;
- excipients: propylene glycol - 1250.0 mg, sorbitol (sorbitol) - 2000.0 mg, succinic acid - 12.5 mg, eucalyptus leaf oil (eucalyptus oil) - 0.75 mg, sodium benzoate - 2.5 mg , apricot flavor - 5.0 mg, water (purified water) - up to 5 ml.
Bromhexine tablets are a mucolytic drug that is created to improve the motility of the glands of the bronchial tree and synthesize the lung's own secretions, which reduces the viscosity of thick sputum that clogs the bronchial space. The drug has a pronounced expectorant effect, facilitates the excretion of mucus outside the lungs, softens a strong dry cough and promotes its transition to a productive form. This drug belongs to the category of low-toxic drugs, therefore, it is well absorbed by the body of patients of different age groups. Bromhexine tablets practically do not affect blood circulation in the respiratory system and have a minimum set of side properties.
The cost of this plate of Bromhexin tablets is 45-55 rubles. This package contains 10 tablets coated with a special coating so that the dissolution and absorption of the drug does not take place in the stomach, but in the intestines. This increases therapeutic effect, and the active components of the drug in a larger volume enter the bloodstream, and with it directly into the lung tissue. The medication is dispensed without a special prescription from the attending physician, and you can buy it in almost every pharmacy that sells medicines.
Bromhexine tablets are intended for the treatment of severe dry cough of an infectious and cold origin. The drug is able to translate dry cough into its productive form due to the fact that it can liquefy thick sputum to the limit until it begins to leave the lungs on its own during the next bronchial spasm. Due to the expansion of the bronchial space, the patient feels that his breathing has become much cleaner and easier, gas exchange improves, and the bloodstream is saturated with a large volume of oxygen. The latter physiological factor plays a key role in enhancing the body's immunity and resistance to infectious agents of pulmonary disease.
Contraindications
Bromhexine tablets do not have a large list of contraindications. The drug is well absorbed and practically does not provoke atypical reactions of the body. Still, you should refrain from taking this medication in the following cases, namely:
- In the first trimester of pregnancy. At this stage of fetal development in the body of the unborn child, the foundations for the stable functioning of all vital organs and systems are laid. Taking Bromhexine tablets by a pregnant woman can negatively affect the health of the child's respiratory system.
- Peptic ulcer disease. The drug slightly increases the general acidity of gastric juice, therefore, if the patient initially already has a predisposition to peptic ulcer disease and inflammatory processes in the digestive tract, then you should not carry out therapy with Bromhexine. Exacerbation of gastric ulcer threatens with serious consequences for the patient's health and may result in emergency hospitalization.
- Allergy. Individual predisposition to allergic reactions on the active components of Bromhexine manifests itself in the form of urticaria, skin itching, profuse rashes on the abdomen, chest, neck and upper extremities. Particularly severe forms of allergies can manifest as bronchial spasm and swelling of the nasopharyngeal mucosa.
- Lactation. Breastfeeding a baby is the circumstance that prohibits the simultaneous administration of Bromhexine tablets. The active substances of the medication can enter the mother's milk, and with it into the baby's body. The child's reactions to this drug can be very different, but they all belong to the category of negative and not conducive to strengthening the child's body.
- Gastric bleeding. There is a certain category of people who have congenital weakness of the capillary vessels of the stomach. Such patients suffer from periodic discharge of blood into the digestive organ. Bromhexine tablets are capable of activating this pathological process and provoking a larger-scale release of blood. The latter condition of the body can lead to a sharp decrease in blood pressure and surgery to eliminate blood loss.
The attending physician, after examining the patient, can establish the presence of additional limiting factors that exclude the intake of Bromhexine tablets in view of the fact that this drug will not be advisable to use in a specific therapeutic case.
Indications for use
Bromhexin tablets are prescribed by the attending physician by a pulmonologist if the following pulmonary diseases are detected in a patient, namely:
The attending physician may prescribe Bromhexine tablets as an independent drug, or as part of complex therapy to achieve maximum therapeutic effect in a short period of time.
Instructions for the use of Bromhexine tablets
The procedure for taking this medication for patients of the adult age category and children is established individually. Accordingly, the therapeutic dosage is also determined as follows, namely:
For kids
A child whose age is from 1 to 2 years is indicated for taking 2 mg. the drug 3 times a day. Children aged 2 to 6 years receive a dosage of 4 mg. medicines 3 times a day. A child of the age category from 6 to 10 years old should take 6-8 mg. medication 3 times a day. Children over 10 years old already receive adult dosage which is in the range of 8 mg. 3-4 times a day.
For adults
Therapy for adult men and women involves taking Bromhexine in a dose of 8 to 16 mg. 4 times a day. This is the optimal amount of the drug, which allows you to effectively fight inflammation in the organs of the respiratory system, activate the secretory function of the bronchi and accelerate the outflow of sputum until complete recovery. The duration of one therapeutic course is from 10 to 15 days.
In most cases, in adults and children, the first signs of a therapeutic effect appear as early as 4-6 days from the start of taking Bromhexine tablets. At the insistence of the doctor, taking the medication may last longer than the period recommended in the instructions. Also, the drug is allowed to be used for prevention stagnation in the postoperative period, when the respiratory organs, and especially the lungs, were subjected to surgical intervention.
Side effects
Bromhexine tablets do not have a pronounced toxic effect, but despite this, the drug has a number of side effects... They manifest themselves in the form of the following atypical reactions of the body:
- Organ disorder gastrointestinal tract... Irritation of the gastric mucosa by the active components of Bromhexine tablets can lead to the patient beginning to experience nausea, abdominal pain, heaviness in the right hypochondrium, lack of appetite. The development of diarrhea and vomiting with dehydration of the body is not excluded.
- Dizziness. Bromhexine practically does not affect blood circulation, but patients with weak cerebral vessels may experience moderate pain in the temples and the back of the head. In such cases, it is recommended that you stop taking the pills and take a pain reliever. You also need to measure blood pressure... If it is increased, then you need to immediately call ambulance to stabilize the state of health.
- Allergy. Patients prone to allergic reactions may experience itchy skin, a red rash on various parts of the body (most often the rash is formed on the abdomen), urticaria, bronchial spasm, or swelling of the nasopharyngeal mucosa.
This is an exhaustive list of possible side effects that have been documented in multiple clinical trials. Also, do not discount the factor of individuality of each patient's organism. Other indirect manifestations of non-perception of the drug are not excluded. Therefore, in the process of treating pulmonological diseases with Bromhexine tablets, accompanied by a strong dry cough, it is necessary to listen to the behavior of your body.
One of the most famous drugs that are used in the fight against a debilitating cough is the proven "Bromhexine". Analogs of this drug will be studied in our article, since this information is important for people who do not have the opportunity to purchase exactly "Bromhexine", or there is such a rare phenomenon as an individual intolerance to the drug.
The correct alternative to the drug can be selected only by carefully studying its composition and principle of action. Bromhexin was no exception. Instructions, price, reviews, analogue (the price will also be indicated) - all this information is presented in our article below.
The main active ingredient and the principle of action of the drug
"Bromhexine" (analogs of which we will discuss in detail below) is positioned as a mucolytic drug that activates sputum discharge and thus has an expectorant and weak antitussive effect. The main active ingredient in the preparation is bromhexine hydrochloride. The prototype for its synthetic creation was a plant called Adhatoda vasica. Scientists have noticed that the extract of this plant promotes easier sputum discharge, and they created its synthetic analogue, which served as the basis for the creation of such a drug as Bromhexin (price, reviews, analogs we will certainly study further).
Its principle of action is that bromhexine hydrochloride is able to depolarize acidic saccharides of bronchial secretions. Due to this, the viscosity of the sputum is reduced. The activity of the ciliated epithelium is significantly increased, which makes it easier to cough up sputum.
Indications for appointment
"Bromhexin" (instructions for use, the price, analogues of which are discussed in this article) is considered a simple, but quite effective drug. The indications for its appointment are a variety of respiratory diseases, accompanied by the formation of thick, viscous, difficult to separate sputum:
- bronchial asthma;
- tracheobronchitis;
- acute bronchitis;
- alveolitis;
- chronic bronchitis (obstructive);
- chronic pneumonia;
- cystic fibrosis.
Types of "Bromhexine" and the main manufacturer of the drug
Most of the Bromhexine that is available to our customers is manufactured by a German pharmaceutical company called Berlin-Chemie. This manufacturer produces the drug in tablet form.
For use by adult patients, there are yellow or pink tablets containing 8 mg of bromhexine hydrochloride. They are available in packs of 20. For children, the manufacturer produces tablets with a lower dosage of the active active ingredient - 4 ml. They are available in packs of 10, as well as in dark glass bottles containing 50 tablets.
"Bromhexin" Berlin-Chemie (analogues to which it is quite easy to pick up, having studied the basic principle of the drug's action) is also available in the form of a green dragee containing 4 mg of active substance (in a package of 50 pcs.). In addition, the drug is produced in the form of an elixir, 5 ml of which contains 4 mg of bromhexine hydrochloride.
Bromhexin Berlin-Chemie, whose analogues can be easily found among the products of other manufacturers, is also produced by such domestic pharmacological manufacturers as Akrikhin, Biosintez, Pharmstandard.
It is also produced by such pharmacological plants as JSC Greenvex (Latvia), Darnitsa (Ukraine), and FK Zdorovye (Ukraine). In addition to the same tablets of 8 mg and 4 mg, these manufacturers also offer "Bromhexin" in the form of a syrup, which can be produced in various packages: 60 ml, 80 ml, 100 ml and 120 ml.
"Bromhexine": price
Analogs of this drug will be presented further, as for the cost of "Bromhexine" itself, it differs depending on its form of release and dosage. Also, the price may vary insignificantly depending on the manufacturer and the markup that pharmacies make. On average, the cost of the drug is as follows:
- 8 mg tablets (20 per pack) - from 20 rubles. up to 60 rubles;
- 4 mg tablets (50 pcs.) - about 60 rubles;
- dragee 8 mg (25 pcs.) - from 90 rubles. up to 135 rubles;
- syrup (100 ml) - from 75 rubles. up to 150 rubles.
Customer Reviews
"Bromhexine" (analogues of which are more expensive than the drug itself) is relatively affordable for most of the population. In comparison with other similar drugs, its cost and availability allows you to purchase the drug immediately after a doctor's appointment. In many ways, it is the price of the described medication that determines the large number of positive reviews that buyers leave about it.
People write that the first effect of taking the drug is noticeable as early as 2-3 days. It actually relieves dry, debilitating and unproductive coughs, thinning phlegm and making it easier to pass.
"Bromhexin" is a syrup, analogs to which pharmaceutical companies also produced in sufficient quantities, has another advantage. It comes with a pleasant apricot flavor, which makes it easier for children to take. Little patients take such a sweet and tasty medicine more readily than conventional pills.
"Bromhexine": analogues (synonyms) of the drug containing bromhexine hydrochloride
Seeing in the pharmacy such drugs as, for example, "Bromhexin-Akrikhin", "Bromhexin 8", "Bromhexin 8 Berlin-Chemie", etc., do not be mistaken and think that these are all analogues. You need to understand that this is all - this is the same drug, which, depending on the dosage, contains 8 mg or 4 mg of the same active ingredient in one tablet - bromhexine hydrochloride. The only difference between these drugs is manufacturer and cost.
This list of synonyms-analogs, which contain the same active substance as "Bromhexin", can be continued with the following drugs:
- "Mugotsil".
- Bromobene.
- Bisolvon.
- Mukovin.
- Fulpen A.
- Brokokin.
- Solvin.
- "Lysomucin".
- "Bromhexine chloride".
These drugs may differ in various excipients that make up their compositions, but they have one main active ingredient. Accordingly, they have the same principle of action, indications and contraindications for use, as well as "Bromhexin".
Full analogs of "Bromhexine"
Thanks to the developed pharmaceutical production and the huge number of medicines it produces, almost any drug today can be replaced with another, let's go with it in action. Bromhexin was no exception. Analogues, instructions for use and the composition of which we will further consider, are provided in large quantities, but the most popular and demanded among them are:
- "ACC".
- "Doctor Mom".
- "Lazolvan".
The active substance in the composition of these drugs, indications for use and the average cost will be discussed in detail by us below.
"ACC" is one of the most famous antitussive drugs
This drug is really familiar to those who have chronic diseases respiratory tract... It has 3 forms of release, among which - effervescent tablets, powder (for self-preparation of a hot drink) and syrup.
The main active ingredient is the substance acetylcysteine. Once in the body, this synthetic component breaks the bisulfide bonds of mucopolysaccharides in the sputum.
Thanks to this, "ACC", like all other analogue preparations of "Bromhexin", liquefies thick phlegm and promotes its easier and more active discharge. This drug is successfully prescribed for problems and diseases such as:
- sinusitis;
- bronchiectasis;
- tracheitis;
- obstructive, chronic, acute bronchitis;
- cystic fibrosis;
- laryngitis;
- otitis media with effusion;
- bronchiolitis.
The cost of the drug depends on the content of acetylcysteine in 1 tablet or 1 packet:
- tablets "ACTS 100" (1 tablet contains 100 mg of acetylcysteine) cost about 250-300 rubles. (20 pcs in a pack);
- tablets "ACTS 200" - 250 rubles;
- tablets "ACTS 600" - 280 rubles;
- packaging of bags with ACTS100 powder (1 packet contains 100 mg of acetylcysteine) costs about 130-150 rubles. (20 packages);
- powder "ACTS 200" (20 packages) - about 140-170 rubles;
- powder "ACTS 600" (6 packages) - 140 rubles;
- syrup 100 ml - 220 rubles and 200 ml - about 300 rubles;
It is difficult to come across negative reviews about "ACC", since it is really effective in fighting coughs. Some people call its only disadvantage high, in comparison with other analog drugs, the price.
Doctor Mom is one of the best alternatives to Bromhexine syrup
This remedy is a herbal preparation, because it contains an extract of more than 10 medicinal herbs, which include turmeric, licorice root, cubeb pepper and aloe. The drug is available in the form of lozenges, warming ointments, but the most popular is the Doctor Mom syrup.
The principle of action of this herbal preparation lies in the fact that due to its mucolytic, bronchodilatory and expectorant action, it, like Bromhexin, dilutes phlegm, facilitates its discharge when coughing, thereby cleansing the bronchi and relieves inflammation.
Thanks to its medicinal action this drug is effective in the treatment of various acute and chronic diseases respiratory tract:
- bronchitis;
- tracheitis;
- laryngitis;
- pharyngitis.
The manufacturer's recommended price for 1 bottle of syrup (100 ml) is 165 rubles, but it may vary slightly from the pharmacy markup. Customer reviews of this drug are mostly positive. Patients note that "Doctor Mom" really looses cough and facilitates sputum discharge. The first results are noticeable after just a few tricks. In addition, the syrup has a residually pleasant taste and is suitable for both adults and children (starting from the age of three).
"Lazolvan" - a real salvation from a debilitating cough
This drug is also quite popular and is often prescribed by doctors. It is available in the form of tablets, syrup, solution in ampoules for intravenous administration and in vials for oral administration.
The main component in its composition is ambroxol hydrochloride, which activates the production of mucus in the respiratory tract and promotes its release from the bronchi. Thus, the cough becomes moist and productive.
This drug has enough wide range indications for use, including:
- obstructive pulmonary disease;
- BA accompanied by severe sputum discharge;
- pneumonia;
- chronic and acute bronchitis;
- bronchiectasis.
The average cost of tablets (20 pcs.) Is 165 rubles, lozenges for resorption (20 pcs.) Cost about 200 rubles, syrup (100 ml) - 205 - 290 rubles, and a solution for inhalation and internal use(100 ml) will cost about 350 rubles.
How to make the right choice
We can conclude that "Bromhexin", the instructions for use, the analogs of which are discussed above, is sufficient effective drug... Moreover, its price is available to most of the population. In pharmacies you can find drugs that are almost the same as "Bromhexin" medicinal effect, while their price exceeds the cost of "Bromhexin".
Despite the fact that all analog drugs have a good reputation, and customer reviews about them are mostly positive, we recommend that you buy any drug only on the basis of a medical prescription. Indeed, despite the same principle of action, one should not forget that the active substances of all these drugs are different.
For pathologies of the respiratory tract, a symptom of which is a cough, doctors often prescribe Bromhexine. Although it is more convenient for children to use such a drug in syrup or in the form of a solution, Bromhexine is also produced in tablets. From what age is it permissible to use them, in what dosage do they give Bromhexine tablets to children and what other medications can replace it?
Manufacturers and release form
The tablet form of Bromhexine is available:
- Latvian manufacturer Grindeks. Such Bromhexine is intended for children, therefore it is presented in a dosage of 4 mg in one tablet. One pack of this medicine contains 50 tablets.
- Russian manufacturers Dalkhimpharm, Biosynthesis, Pharmstandard-lexredstva, Obnovlenie, Atoll, Yodillia-farm, Medisorb, Uralbiopharm. All of these companies produce Bromhexine tablets, each containing 8 mg of the active compound. One pack can contain from 10 to 50 tablets.
- Domestic manufacturer Akrikhin. The range of drugs of such a company includes both tablets with 8 mg of bromhexine and a drug for children (tablets containing 4 mg of the active ingredient). One pack of such Bromhexine can contain from 10 to 100 tablets.
- Berlin Chemie from Germany. This manufacturer offers Bromhexine in the form of yellow-greenish dragees containing 8 mg of active compound.
Composition
Bromhexine hydrochloride acts as a compound providing a therapeutic effect to Bromhexine tablets. Additional components of the drug are lactose, starch, wax, sucrose, silicon dioxide and other compounds, which should be specified in the annotation to the selected medication.
Operating principle
Bromhexine is classified as a drug with a mucolytic effect, since its main component liquefies mucoprotein and mucopolysaccharide fibers in sputum.
As a result of this action of bromhexine, the viscosity of the sputum decreases, and its volume increases. This causes the expectorant effect of the drug, thanks to which the medication helps to get rid of cough.
Also, bromhexine is noted for the ability to improve the formation of a surfactant.
Indications
Instructions for the use of Bromhexine tablets recommend giving such a medicine for diseases of the respiratory tract, if the patient's bronchial secretions are excessively viscous and clears his throat with great difficulty. The medicine is used for bronchitis, inflammation of the lung, the appearance of bronchiectasis, asthma, tuberculosis. Also Bromhexine is prescribed for cystic fibrosis.
At what age is it allowed to take
Brogmexin tablets intended for children are not recommended for use earlier than 3 years of age.
If it is required to give the drug to a child under 3 years old, a liquid form of Bromhexine (solution / syrup) is used in the treatment, which is approved for use under the supervision of a pediatrician from birth. Tablets, in which the content of the active ingredient is 8 mg, is not prescribed for children under 6 years of age.
Contraindications
Tableted Bromhexine should not be used in children with hypersensitivity to any of the components of the drug. Also, such a medicine is contraindicated in ulcerative lesions of the gastrointestinal tract in the acute stage. Special care from the pediatrician is also required by the appointment of Bromhexine to children with kidney disease or hepatic disease, as well as bronchial asthma.
Side effects
For the use of Bromhexine children's organism can "answer":
- Dyspepsia.
- Dizziness.
- Skin rash.
- An increase in the activity of liver enzymes.
- Headache.
- Increased sweating.
- Bronchospasm.
If such symptoms occur during the treatment period, the drug is recommended to be canceled.
Instructions for use
Bromhexine tablets should be taken three times a day. You can drink the medicine both before and after meals. The duration of treatment is determined for each child individually, but the time limit is 4-28 days.
A single dose of the drug depends on the age of the little patient:
- Children 3-5 years old are given 1 children's tablet containing 4 mg of bromhexine.
- Over the age of 6 years, a single dose of the drug will be either 2 children's tablets or 1 tablet with 8 mg of the active compound.
If necessary, the dosage can be increased by a doctor to 16 mg per dose.
Instructions for Bromgensin from Berlin-Chemie:
Overdose
If you exceed the dose of Bromhexine, it will lead to nausea and other negative symptoms from the digestive tract. If an overdose is found within one to two hours after taking an excess of pills, it is recommended to provoke vomiting, and then give the child a lot of liquid.
Interaction with other drugs
Bromhexine is successfully combined with antibiotics, bronchodilators and many other medicines used in diseases of the respiratory system. It is not recommended only to combine this drug with antitussives, because inhibition of the cough reflex with simultaneous dilution of sputum can provoke secretion stagnation and deterioration of the patient's condition.
Terms of sale
Storage conditions and shelf life
Keep Bromhexine tablets at home in a dry place out of sunlight. It is important that the tablets cannot be obtained by a small child. The storage temperature should not be higher than +25 degrees. The shelf life differs from company to company and can be either 2 or 3 years, or 5 years or more.
Name: Bromhexin (Bromhexin)
Pharmacological effects:
It increases the secretion of secretions by the bronchial glands and lowers the viscosity of sputum, which gives a pronounced expectorant result and facilitates the secretion of sputum. The drug is low-toxic. It has no significant effect on blood circulation.
Bromhexine - indications for use:
Acute and chronic inflammatory diseases of the trachea, bronchi, lungs; bronchiectasis (lung disease with the formation of cavities filled with sputum in the lung tissue), pneumoconiosis (common name occupational disease respiratory organs); in the pre- and postoperative period, the drug is used for bronchography.Bromhexine - method of application:
Bromhexine is taken orally (regardless of the intake) in the form of tablets. Dosages for adults - 0.016 g (16 mg = 2 tablets of 0.008 mg) 3-4 times a day; for children from 3 to 4 years old - 0.002 g (2 mg), from 5 to 14 years old - 0.004 g (4 mg) 3 times a day; children under 3 years of age are not prescribed the drug.The effect of the drug begins to manifest itself often within 24-48 hours after the start of treatment. The course of treatment is from 4 days to 4 weeks.
For inhalation use, the solution should be diluted 1: 1 with distilled water and heated to body temperature to prevent coughing. In patients with bronchial asthma or asmatic bronchitis, a bronchodilator (a means that expands the lumen of the bronchi) should be taken before inhalation. Inhalation is carried out twice a day for adults, 4 ml, for children over 10 years old - 2 ml each, children aged 6 to 10 years old - 1 ml each, children aged 2 to years old - 10 drops each and children under 2 years old - each 5 drops for inhalation. Parenteral (bypassing the digestive tract) administration of the drug is offered for treatment in severe cases, as well as in the postoperative period to prevent the accumulation of thick phlegm in the bronchi. 1 ampoule is administered subcutaneously, intramuscularly or intravenously 2-3 times a day slowly for 2-3 minutes. The drug is administered intravenously together with glucose or saline solution. The drug is incompatible with alkaline solutions.
If necessary, bromtexin is prescribed simultaneously with antibacterial, bronchodilator, cardiac and other agents.
Bromhexine - side effects:
Rarely, with prolonged use - nausea, vomiting, dyspeptic symptoms (digestive disorders), exacerbation of peptic ulcer disease. It is extremely rare - angioedema (allergic) Quincke's edema, an increase in the level of transaminases (enzymes) in the blood serum.Bromhexine - contraindications:
There are no absolute contraindications. Relative: hypersensitivity to drugs, peptic gastric ulcer, recent gastric bleeding, first trimester of pregnancy.Bromhexine - release form:
Tablets 0.008 g, 0.016 g. Dragee 0.004 g, 0.008 g, 0.012 g. Syrup (1 ml - 0.0008 g). Potion (1 ml -0.0008 g). Solution for oral administration (by mouth) (1 ml - 0.002 g). Elixir (1 ml - 0.0008 g, or 0.00016 g) Solution for inhalation use (1 ml - 0.0002 g). Solution for parenteral administration (1 ml - 0.002 g).Bromhexine - storage conditions:
Regular.Bromhexine - synonyms:
Bromhexine chloride, Bisolvon, Mukovin, Solvin, Brexol, Brodizol, Bromobene, Bromxin, Bizolvon, Bromobenzonium, Brokokin, Lizomucin, Mugotsil, Fulpen A.Important!
Before using the medicine, you should consult your doctor. This manual is for informational purposes only.
