Instructions for use

Prospan instructions for use

Dosage form

Composition

dry ivy leaf extract, extractant - ethanol 30% / 5-7.5: 1 / 7mg; Auxiliary substances: water, potassium sorbate, lemon acid b / water, sorbitol liquid crystal, xanthan gum, cherry flavor

Pharmacodynamics

In pharmacological and clinical studies, Prospan syrup exhibits a secretolytic effect.

In vitro studies using immunohistochemical and biophysical techniques have shown that alpha-hederin indirectly affects the stimulation of beta2-adrenergic receptors and inhibits the internalization of these receptors in type II pneumocytes, resulting in relaxation of bronchial smooth muscles and a decrease in mucus viscosity.

Ivy saponins have an effect close to that of a surfactant, thinning thick mucus in the respiratory tract and increasing the activity of the cilia of the ciliated epithelium blocked by it.

Monocentric clinical research tolerance and effectiveness of syrup Prospan in a dosage 4 times a day, 1-2 tablespoons for 4 weeks, with the participation of 26 children aged 4-10 years, showed an improvement in spirometric parameters, a decrease in the severity of shortness of breath, a decrease in the frequency of coughing attacks.

In a comparative study of the clinical efficacy of Prospan syrup at a dosage of 3-5 times a day, 2 tablespoons and acetylcysteine ​​at a dosage of 3 times 100 mg each in 20 children with chronic obstructive diseases respiratory tract the comparable efficacy of both drugs was determined. Prospan syrup relieved cough and shortness of breath. Shown is the stimulating effect of the studied syrup on expectoration, as well as the antispasmodic effect.

Side effects

Perhaps: allergic reactions; when using the drug in the form of a syrup, there may be a loosening of the stool (due to the content of sorbitol)

Selling features

Available without a prescription

Indications

It is used as an adjuvant in acute and chronic inflammatory diseases of the respiratory tract, accompanied by a cough.

Contraindications

Prospan syrup is not allowed to be used in patients with hypersensitivity to any of its components. The drug contains sorbitol. If the indicated dosage regimen is observed, the patient receives up to 2.9 g of sorbitol with each portion of the syrup taken.

Drug interactions

Until now, there have been no cases of interaction of Prospan syrup with other pharmacological agents... The drug can be prescribed, inter alia, in conjunction with antibiotics

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Mode of application

Dosage

Children aged 6-9 years take 5 ml of syrup 3 times a day (corresponds to 630 mg of active ingredient)

Children aged 1-5 years take 2.5 ml of syrup 3 times a day (corresponding to 315 mg of active ingredient).

Children under the age of 1 year take 2.5 ml of syrup 2 times a day (corresponds to 210 mg of active ingredient)

Measure the syrup using the supplied measuring cup.

Shake the syrup bottle before each use!

Treatment with the drug should continue for at least 7 days, even with mild inflammatory processes in the respiratory tract. For long-term therapeutic effect it is recommended to continue treatment for another 2-3 days after the disappearance of the symptoms of the disease.

Colds is Prospan. The ATX code is R05C A. It is classified as an expectorant.

Composition release form packaging

Prospan is a plant-based mucolytic medication. It comes in two pharmaceutical forms:

1. Effervescent tablets (Prospan Forte). The package contains 10 tablets, 65 mg each.
2. Syrup ("Prospan"). The medication is produced in bottles (100 ml). 1 ml of syrup contains dry ivy leaf extract (7 mg). Of the auxiliary substances, we indicate: sorbitol solution, anhydrous citric acid, potassium sorbate, purified water, cherry flavor, xanthan gum.

Manufacturer

Germany produces medication (Engelhard Arzneimittel GmbH & Co. KG).

Indications

The drug is prescribed in the treatment of such diseases:

• Bronchial obstruction syndrome.
• Bronchitis (acute, chronic form).
• Bronchial asthma.
• Diseases of the respiratory system, accompanied by a cough with difficult, very thick sputum.

Contraindications

Contraindications for use should indicate:

1. Fructose intolerance. The medication contains fructose.
2. The presence of one of the components of the drug.

Mechanism of action

The drug is used in the treatment of diseases of the respiratory system with an inflammatory etiology, accompanied by a cough. Ivy leaf extract contains saponins (glycosides). The drug has the following effects:

• antitussive;
• mucolytic;
• mucokinetic;
• secretolytic;
• antispasmodic.

Due to the presence of saponin glycosides in ivy extract, the secretions of the bronchi are liquefied. Some glycosides have a parasympatholytic effect on the respiratory system. Due to the stimulation of beta2-adrenergic receptors of the epithelium of the lungs, smooth muscle structures of the bronchi, an adrenergic effect is obtained.

At the same time, calcium ions penetrate less into the cells, exerting an antispasmodic effect. One of the advantages of the medication is the absence of an effect on the central regulation of the respiratory function.

Instructions for use

The duration of the therapeutic course is influenced by such factors as: the nature of the course of the pathology, the brightness of the symptoms. The minimum course prescribed by doctors is usually a week.

To achieve a pronounced lasting therapeutic effect, it is recommended to take the medicine in the dose indicated by the doctor for 2 to 3 days, after the main signs of the disease have been eliminated.

"Prospan" in the form of tablets (effervescent) is dissolved in cool / hot water (200 - 250 ml.). The hot drink enhances the antispasmodic effect.

• Children aged 4 to 12 years are prescribed to take the medicine three times a day, half a tablet.
• Children over 12 years old should take the drug twice a day, 1 tablet.

"Prospan" in the form of a syrup must be shaken before use. Prospan in the form of drops can be used for inhalation.

• Children from 0 to 6 years old take 2.5 ml three times a day.
• Children 6 - 14 years old take the medicine three times a day, 5 ml.
• Adults take the medication three times a day, 5 - 7.5 ml.

Side effects

When using syrup, side effects such as a laxative effect can occur. In some cases, allergies appear:

If the patient has hypersensitivity, the drug can cause disorders in the functioning of the gastrointestinal tract:

• diarrhea;
• abdominal pain;
• nausea.

This medication is usually very well tolerated.

Overdose

If you take the medicine in a dosage that is three times higher than that recommended by the doctor, diarrhea and nausea may occur. To eliminate such signs, symptomatic therapy is needed.

special instructions

The drug can be used in the treatment of pregnant and lactating women. But the treatment should be carried out strictly under the supervision of a specialist. Special studies of the effect of the drug on the course of pregnancy, childbirth, and fetal development have not been carried out.

The syrup does not contain substances such as:

• sugar;
• alcohol;
• dyes.

Sick diabetes mellitus the medicine should be taken with caution. In 2.5 ml. syrup contains sorbitol (0.963 g).

Taking medication does not have any effect on the ability to drive any vehicle, perform actions that require increased concentration of attention, speed of psychomotor reactions.

Drug interactions

The medication is allowed to be used simultaneously with other medicinal products. Precise information on adverse drug interactions has not been reported.

Do not use Prospan with antitussive medicines. In this case, there is difficulty in coughing up liquefied sputum.

Prospan: instructions for use and reviews

Today, the pharmacy chain offers an impressive range of medicines that are used to treat inflammatory processes respiratory system of the human body.

All these medicines have their own special properties and their use should be carried out in accordance with the attached instructions or on the individual recommendation of the attending physician.

For ease of use, the pharmaceutical industry produces such drugs in various forms:

• in the form of tablets;
• in the form of a medicine;
• in the form of a syrup;
• in the form of lozenges;
• in the form of drops.

One of the most effective means among this group of drugs is Prospan. This drug is made from herbal ingredients and has the following properties:

• acts as an antitussive agent;
• acts as an expectorant;
• used as a mucolytic drug;
• has antispasmodic properties.

With such a spectrum of features, the medicine does not inhibit the cough center of the brain... The main component of Prospan is dried ivy leaf extract, which is usually used to treat of various kinds cough.

The drug is very widely used to treat colds in children. Due to the existing pleasant taste, the child uses it without any problems.

Indications for use

Based on the properties of the drug, Prospan syrup and drops are used as expectorant in the following situations:

• in the event of acute and chronic inflammation of the respiratory system;
• the presence of a cough, in which the process of separating sputum is difficult.

Due to the content of the plant element in the preparation, the viscous state of sputum decreases. Is happening speedy airway clearance from her.

In addition, the phytocomponents of Prospan have biologically active elements that have a therapeutic effect on the human body as a whole.

Contraindications for use

Syrup and drops of the drug should not be used:

• in the presence of intolerance to any of the components that make up the drug;
• children under 1 year old;
• people suffering from alcoholism;
• in the presence of other diseases that prohibit the use of ethyl alcohol.

Inhalation with Propane is contraindicated for use if the child has problems such as:

• hypersensitivity to the drug;
• bronchial asthma;
• the child has not reached 2 years of age.

It is necessary to use the drug with extreme caution in the presence of lesions of the brain, liver and craniocerebral trauma.

Side effects

Sometimes, when using Prospan, the following side effects on the body are possible:

• hives;
• rash;
• dyspnea;
• swelling of the mucous membranes.

In such situations, you should stop taking the drug and urgently consult your doctor.

Forms of issue

The drug Prospan is available in the following forms:

1. Syrup... The liquid is rather cloudy, has a light brown color and has a cherry smell. Available in dark-colored bottles of 100 ml or 200 ml.
2. As a packaged syrup (sachet)... The syrup of the drug is packaged in 5 ml sachets.
3. In the form of drops... It is produced in dark bottles with a special stopper with a dispenser. Vials are available in 20 ml, 50 ml and 100 ml volumes.

Prospan for children - instructions for use

Depending on the form of release, the presence of the main component in the preparation, the dry extract of ivy leaves, also differs. For example, 1 ml of cough syrup contains 7 mg of ivy extract, and 1 ml of the drop form of the drug contains 20 mg. This is what distinguishes the age limits for taking the medicine, as well as the possibility of using the drug during pregnancy and breastfeeding.

The main indicators can be clearly demonstrated in the following table:

Prospan syrup

In accordance with the rules of admission, the drug in the form of a syrup must be shaken before use. Prospan for children, according to the instructions for use, must be used in the following dosage:

• child aged from birth to 1 year take 2.5 ml twice a day;
• child aged 1 to 6 years take three times a day, 2.5 ml;
• for a schoolchild and a teenager take 5 ml three times a day.

For adults, unless otherwise prescribed by the attending physician, Prospan should be consumed three times a day at a dosage of 5 ml to 7.5 ml.

A special cup for measuring the syrup dose is supplied with the Prospan bottle. The duration of taking the medication depends on the patient's condition and the characteristics of the course of the disease. In accordance with the instructions, the minimum duration of the drug should be at least one week. In order to consolidate the achieved result, Prospan should be taken within two or three days after the cough and other symptoms associated with the disease have passed.

Prospan syrup packaged

Prospan syrup packaged is produced already dosed for one dose. One dose is 5 ml of the drug.

According to the instructions, adults can take Prospan packaged syrup 1 sachet three times a day (unless otherwise prescribed by a doctor), after slightly kneading its contents. In the same dosage, the medicine should be used by children from 6 years of age and older.

Prospan in such a package is convenient to use at work or to bring your child to school with you. The bags are small, do not dissolve in water and do not wash down with water. In addition, the contents cannot be woken up, which certainly makes it easier for a child to use.

In accordance with the instructions, the minimum duration of the drug should be at least one week. In order to consolidate the achieved result, Prospan should be taken within two or three days after the cough and other symptoms associated with the disease have passed.

During the period of treatment, you must carefully monitor the reaction of your body and / or the body of the child. When there is side effects(see details in the Side Effects section), you urgently need to contact your doctor.

If the child's age is in the range of 1 to 3 years, then Prospan should be taken 3 to 5 times during the day at a dosage of 10 drops.

If the child's age is from 4 to 7 years old, then the medicine should also be taken from 3 to 5 times during the day, but in a dosage of 15 drops.

For schoolchildren and adults, take the drug also during the day from 3 to 5 times in a dosage of 20 drops.

Drops of Prospan should be drunk before meals, children should dissolve the dosage of the product in a small volume of water.

How to make propane inhalation?

In some cases for treatment viral diseases inhalation is required. To do this, use Prospan, produced in the form of drops, and any special devices for inhalation (spraying the drug) without heating. Previously, the medicine must be diluted with water in a ratio of 1 ÷ 2. Saline can be used instead of water.

Pour Prospan into a specialized inhalation device in a dosage of 20 to 25 drops, add water (saline) in the above ratio. The treatment should be carried out 3 to 5 times a day. Inhalation with Prospan helps very well.

Overdose

When using the drug in a dosage much higher than the daily norm, a state of nausea may occur, vomiting may appear and diarrhea may occur.

The tool should not be used in conjunction with drugs that have an antitussive effect, because this complicates the process of sputum outflow.

Prospan syrup and drops are dispensed in the pharmacy network without presenting a medical prescription.

Prospan, produced in the form of a syrup, can be used for three years, and in the form of drops for five years.

Separate conditions

The medicine should be kept away from children.

Store at temperature conditions not exceeding + 25 ° С.

During storage, the color of the preparation may change to a more turbid one, a small precipitate may fall out or the taste may change slightly. These changes will not affect the healing qualities of Prospan.

During the use of the product, care should be taken when driving a vehicle.

Prospan's analogs

The drug has a fairly large number of drugs with a similar spectrum of action. Here is some of them:

Prospan is a herbal medicine with bronchospasmolytic and expectorant effects.

Release form and composition

Prospan is available in two dosage forms: syrup and oral drops.

Syrup (light brown, slightly cloudy liquid with a cherry smell) in 1 ml contains 7 mg of dry extract of ivy leaves (extractant: 30% ethanol) and excipients: anhydrous citric acid, potassium sorbate, liquid crystallizing sorbitol, xanthan gum, purified water and cherry flavor. 100 ml and 200 ml each in dark glass vials with a dosing stopper.

Drops for oral administration and inhalation contain in 100 ml 2 g of ivy leaf extract (estragent: 30% ethanol). The preparation also contains: anise oil, fennel and peppermint oils, sodium saccharin. 20 ml, 50 ml and 100 ml in dark glass bottles.

Indications for use

Prospan, according to the instructions, is prescribed as an expectorant in the treatment of acute and chronic inflammatory diseases of the respiratory tract, the development of which is accompanied by a cough with sputum difficult to separate.

Contraindications

The use of Prospan is contraindicated in the presence of hypersensitivity to the components included in the product.

The syrup is not prescribed for patients with:

• Fructose intolerance;
• Deficiency of sucrase / isomaltase;
• Glucose-galactose malabsorption.

Prospan in the form of drops should not be used:

• Ingestion: children under 1 year of age, as well as patients with alcoholism and other conditions in which the intake of ethyl alcohol is contraindicated;
• Inhalation method of administration: for children under 2 years of age, as well as for patients, if any bronchial asthma and a predisposition to laryngospasm.

Oral drops are usually prescribed with caution when:

• Traumatic brain injury;
• Liver disease;
• Diseases of the brain.

Method of administration and dosage

Drops of Prospan, according to the instructions, are administered orally or by inhalation.

Inside drops are usually prescribed 3-5 times a day:

• Adults and children school age- 20 drops each;
• Children 4-7 years old - 15 drops each;
• Children 1-3 years old - 10 drops each.

Babies can take drops with fruit juice or honey.

Drops can be used by inhalation, for which 20-25 drops are dripped into a special inhalation device, diluted with drinking water at room temperature (the solution cannot be overheated) in a 1: 2 ratio. Inhaled 3-5 times a day.

Prospan syrup is usually prescribed three times a day:

• Children 1-6 years old - 2.5 ml (1 teaspoon);
• Children of school and adolescent age - 5 ml (2 teaspoons);
• Adults - 5-7.5 ml (2-3 teaspoons).

In mild cases, the duration of the treatment course is 7 days. It is recommended to continue using Prospan for several more days after the symptoms of the disease have disappeared.

Before taking a bottle of Prospan in any dosage form you need to shake up.

Side effects

When using Prospan, allergic reactions may develop.

In some cases, when using the drug in the form of a syrup, the development of a laxative effect was observed, which is associated with the sorbitol included in its composition.

special instructions

Prospan should not be used with antitussive drugs at the same time, as this can make it difficult to cough up liquefied sputum.

The preparation does not contain preservatives or dyes.

Prospan contains alcohol in the form of drops for oral administration (1 drop of the medicine contains 0.013 g of absolute ethyl alcohol, in the maximum one-time adult dosage(20 drops) - 0.25 g of absolute ethyl alcohol). Therefore, during therapy, care must be taken when driving.

When storing syrup and drops, slight changes in taste and slight turbidity are possible, which does not affect the therapeutic effect of Prospan.

Patients with diabetes mellitus should take into account that 2.5 ml of syrup contains 0.963 g of sorbitol (0.08 XE).

Analogs

Prospan's analogs are:

• According to the active substance - Herbion ivy syrup, Gedelix;
• By the mechanism of action - Althea roots, Breast collection No. 1-4, Breast elixir, Doctor Mom, Codelak Broncho, Linkas Lor, Coldrex broncho, Mother and stepmother leaves, Plantain tincture, Licorice syrup, Pine buds, Cough tablets, Amtersol , Sinetos, Cook, Travisil, Bronchipret, Tussamag, Thermopsol, Pectusin, Tussin, Bronchikum, Mukaltin, Pertussin and other expectorant drugs.

Terms and conditions of storage

Prospan is dispensed without a doctor's prescription. Its shelf life, if stored in a dry place at temperatures up to 25 ° C, is:

• Oral drops - 4 years;
• Syrup - 3 years.