BelMEDPreparations (Belarus), Biosynthesis OJSC (Russia), Vertex CJSC (Russia)

pharmachologic effect

Antifungal.

It has an action on dermatophytes, yeast-like and mold mushrooms.

Active with respect to almost all mushrooms, pathogenic for a person, but most of all - red tricophytone and pathogenic yeast-mold, pitiriasis and mycelical forms of the genus Candida.

Quickly absorbed into the gastrointestinal tract.

The maximum concentration is achieved after 2 hours, after receiving at a dose of 250mg.

Almost fully binds to plasma proteins.

It takes histohematic barriers and is distributed over the tissues, high concentrations accumulate in the skin and subcutaneous tissue.

It is distinguished by pronounced epidermo and onychotroposis.

About 70% of the adopted dose is displayed with urine.

Effective with molding methods, tricudes, rubred, epidermofitilation.

The cream is used in an interpultitinine copy of the stop and brushes, ferrocying of smooth skin and multicolored lisp.

Side effect terbinafin

Sensation of gravity and pain in the epigastric area, disorder, decline in appetite, nausea, diarrhea, cholestasis, neutropenia, skin allergic reactions, sensation of burning, redness of the skin, and itching in the field of applying cream.

Indications for use

Fungal lesions of the skin, nails and hair, candidiasis of the skin and mucous membranes.

Contraindications terbinafin

Hypersensitivity, pronounced hepatic cell and renal failure, blood diseases, metabolic diseases, tumors, pathology of limb vessels, pregnancy, breastfeeding, childhood up to 2 years.

Method of application and dosage

Adults and children from 12 years old.

Before applying the cream, it is necessary to clean and dry the affected areas.

The cream is applied once or twice a day with a thin layer on the affected skin and adjacent areas and slightly rub.

In case of infections, accompanied by anelity (under the milk glands, in the interdigable intervals, between the buttocks, in the groin area), the places of application of the cream can be covered with gauze, especially for the night.

Dermatomikosis of the body, the legs:

• 1 week 1 time per day Dermatomikosis Stop: 1 week 1 time Candidiasis Skin: 1-2 weeks 1 or 2 times a day Multicolored Lishe: 2 weeks 1 or 2 times a day Reducing severity clinical manifestations It is usually noted in the first days of treatment.

In case of irregular treatment or premature termination, there is a risk of resumption of infection.

In the event that after one or two weeks of treatment, there are no signs of improvement, diagnosis should be verified.

The dosing mode of the drug in elderly people does not differ from the above.

Overdose

It is possible only when taking inside.

Symptoms:

• head bol
• dizziness
• epigastric pain.

Treatment:

• symptomatic therapy.

Interaction

Increase the plasma concentration of histamine H-2-blockers.

Terfenadine reduces, and rifampicin increases the clearance to 2 times.

special instructions

In the process of treatment, it is necessary to produce antifungal processing of shoes, socks, stockings.

Avoid cream in the eyes, nose, mouth.

Storage conditions

List B.

Store in a dry, protected from light place at room temperature.

Fungal diseases of the skin often appear suddenly. At the same time, the cause of their occurrence is not always associated with violation of the rules of hygiene. Terbanfin cream helps to cope with mikozami, to use which you need competently.

What is the difference in the ointment from the cream of terbinafin?

The preparation of terbinafin is produced in several pharmacological forms. The most common are spray, cream and ointment. At the same time, they are all similar in composition and have one current component. However, its concentration is higher in ointment. Given this feature, it is safe to say that, the cream is almost the same thing. However, due to the fact that the drug has different shape release, there are features of use.

If we consider each form of terbinafin separately, the following features can be called:

Ointment:

• fat and thick;
• practically not absorbed and remains on the surface of the skin;
• requires overlay over marlevary bandage.

Cream:

• soft texture;
• penetrates through the nail plate;
• it is allowed to apply to mucous and wet surfaces;
• can be used with high sweating.

Terbinefin - composition

Terbinefin is a synthetic antifungal drug. Possessed wide spectrum actions. Finding on the mushroom cell membrane, it suppresses the synthesis of sterols in its cells. As a result, the mushroom displaces the substances they need and quickly dies. There is a recovery, the patient feels relief. The result is noticeable after a few days later.

Fast effect is achieved due to the unique composition of the terbinafin. The acting substance is terbinafinhydrochloride. This component has a high activity in relation to various types Mushrooms provoking the development of mycoses. However, not only this substance contains terbinafin cream, the composition of which is as follows:

• benzyl alcohol;
• cetyl alcohol;
• sorbitanastearate;
• cetilpalmitat;
• stearligh alcohol;
• isopropylmiristat;
• purified water;
• sodium hydroxide.

Terbinefin ointment or cream - what is better?

Following the fungal lesions of the skin and nails, patients often can't decide on the choice: terbinafin cream or ointment is better to use. Above noted that this is the same drug in different dosage forms. The type is determined by the sole form of the disease, localization of fungal lesions. At the same time, the rules for the use of medication similar.

Ointment is recommended for use in case of lesion of open skin. At the same time, a small amount of drug is used, thoroughly distributing it throughout the area of \u200b\u200blesion. In order not to be stained with clothing, it is superimposed with a gauze bandage and fix it with a leukoplasty. Cream doctors recommend during fungal lesions of nail plates. It is better absorbed and penetrates deep into, affecting the cause of the disease.

Terbinefin Cream - Indications for use

Having learned from familiar and girlfriends on efficiency drugThe patients are trying to figure out where the cream of terbinafin helps. In order to learn all the testimony for the use of the medication, you need to refer to the instructions attached to the medium. Among the main:

• micoses of skin covers provoked by dermatophytes;
• candidal skin lesions (caused by fungus from the genus Candida);
• multicolored deprived.

Terbinafin - Side effects

The cream for outdoor use terbinefin is well tolerated by patients, even given its synthetic components. Side effects From the use of medication while compliance with all medical appointments relating to the multiplicity of use and the duration of therapy, minimized. However, it is not always possible to completely exclude them. Among the mains side phenomenaarising when using a cream terbinafin:

• allergic reactions;
• burning;
• redness of the skin at the place of application of the drug.

Terbinefin - contraindications

Finding out why the Cream of Terbinafin is used, it is necessary to name the states when it is prohibited. When prescribing medicines, doctors carefully study the history of the patient, learn about the presence of chronic diseases, predisposition to the development of allergies. The absolute contraindication to the use of terbinfin from fungus is an increased sensitivity to its active component or other substances present in the composition. With caution, the medicine is used at:

• renal and liver failure;
• oppression of the work of the red bone marrow;
• tumors;
• metabolic diseases;
• limb vessel diseases;
• childhood up to 12 years old.

Apply terbinefin cream during pregnancy is permissible only by appointing a doctor watching pregnant women. In the event of any reactions from the skin, the worsening of well-being, the future mother should report this to the doctor and stop using cream. It is also necessary to behave using terbinafin during breastfeeding.

Terbinefin - Application

How to apply a cream terbinafin, how many times a day to apply and how long to use - determines the attending physician. Features of therapy are fully dependent on the type of pathology, the stages of violation, the severity of clinical manifestations. The cream should be applied to clean skin in places of lesion and to the surrounding sections with a thin layer. Lightly rubbing the drug, it is evenly distributed over the surface of the entire focus. This procedure is carried out 1-2 times a day.

The duration of terbinafin therapy, cream can vary and depends on the origin of the type of pathology (terbinefin and cream). On average, the cream is used:

• with drumatosis of the body, the legs - 7 days;
• defeats stop - 14 days;
• under the skin - 7-14 days;
• multicolored deprived - 14-21 days.

Terbinefin from nail fungus

Doctors argue that correctly using terbinafin cream, you can get rid of 2-4 weeks. It is important to comply with all the rules for applying funds and follow them:

1. The nail plates on their hands and legs wash and wipe dry.
2. The cream is evenly applied to damaged nails and slightly rub it. Also capture and small sections healthy skin Around the nail.
3. After the use of terbinefin (cream from the nail fungus), they carry out wet cleaning of the premises, handle the shoes with deeschor, change linens. Such events will help prevent re-infection and recurrence.

Terbinefin cream from losing

Antifungal cream terbinafin is effective and against. In this case, after working out the focus, the place of application is covered with a sterile marlevary napkin and fixed with the plaster. Already in the first days, patients note a decrease in the diameter of the hearth, relief of well-being. Therapy should be carried out regularly, in strict accordance with medical appointments. Otherwise, there is a risk of re-infection. If 1-2 weeks of improvement does not occur, the additional examination is carried out. On average, the course of therapy lasts 2 weeks.

Terbanfin cream during thrush

Talking about how the Terbinefin cream is properly used, doctors initially pay attention to the type of pathology. When candidial damage to the skin cream is applied directly to the foci. Previously, they are thoroughly washed under water and dried with a towel with clogs. After applying, terbinafin cream slightly rubbing, which improves its absorption. Processing is carried out 1-2 times a day for 7-14 days (according to the prescription of the doctor, and to the complete disappearance of the skin lesions).

Terbinefin. - this is antifungal drugwhich is used for the treatment of skin, nails, hair and mucous membranes from various infectious fungal diseases. The ointment of terbinefin is made on the basis of hydrochloride and is a chemical derivative, which has a pronounced antifungal effect.

A wide range of applications can be attributed to the advantage of the drug. It successfully struggles with mold, yeast and some kinds of dimorphous fungal infections.

The composition of the drug

The composition of the darkens includes:

• hydrochloride;
• cetostearyl alcohol;
• zetomacrologol;
• glycerol;
• dimethicone;
• poloxamer;
• paraffin;
• benzyl alcohol;
• propylene glycol;
• purified water.

As can be seen, there is not a single natural useful substance in the drug, so ointment, with improper use, is able to cause quite a few side effects.

Indications for the application of ointment terbinafin

Terbanfin ointment is used to treat a large number of diseases, including:

• candidiasis;
• candidiasis of mucous membranes;
• multicolored deprived;
• microsporia;
• Skin and nails.

The Terbinefin also effectively resists with heavy smooth leather dermatomycoses on all parts of the body. Most often, such diseases require system treatmentTherefore, the drug is one of the most suitable for combating such fungal infections.

Contraindications for the use of terbinafin

Among the contraindications to the use of terbinefin ointment, hypersensitivity to the drug and diseases of the kidney of a different nature are found. Lactose deficiency, as well as its intolerance, is also an obstacle to the use of the drug.

Instructions for using ointments

The exact following instruction of ointment and terbinefin cream from fungus will guarantee the correct impact on the course of treatment. Ointment is used externally. Before applying terbinafin on the skin, it is necessary to clean it thoroughly and dry. The procedure should be carried out once or twice a day, while throwing ointment need not only in the affected areas, but also around them.

If the fungus struck the plots that dangle the diameters (in the interfallated intervals between the buttocks, and so on), then after applying the ointment, it is recommended to cover the affected skin area of \u200b\u200bthe gauze. It is extremely necessary to do this if the procedure was produced at night.

Regarding the length of the treatment period, then on average, the course lasts about two weeks. In some cases, improvements do not occur after a week of using ointments, then it is necessary to verify the diagnosis and, possibly, replace the drug to others.

Analogs of ointment terbinafin

Today there are quite a lot of antifungal drugs, so terbinefin ointment has analogs. The most popular of them is thebikur, which is known as enough effective drug To combat fungi. The medicine has an important advantage - when applied, removal of nail plates is not required. The disadvantage is that the course of treatment by tebikur lasts about six weeks. In addition, the ointment cannot be used to get rid of the fungus on the mucous membranes.

Onykhon is considered no less well known, which includes terbinafin. The duration of the course of treatment depends on the skin lesion section:

1. With a dermatomycosis of the stop - from two to six weeks.
2. With the dermatomycosis of the legs and the body - from two to four weeks.
3. When candidiasis of the skin - from two to four weeks.
4. With mycosis of the scalp - four weeks.

Full deliverance from the fungus can come only two weeks after recovery, so in some cases additional drugs are prescribed to secure a positive effect.

Terbafin cream- antifungal drug for outdoor use with a wide range of antifungal activity. At low concentrations of terbinafine has fungicidal activity against dermatophytes (Trychophyton rubrum, Trychophyton mentagrophytes, Trychophyton verrucosum, Trychophyton violaceum, Trychophyton tonsurans, Microsporum canis, Epidermophyton floccosum), yeasts (mainly Candida albicans) and certain dimorphic fungi (Pityrosporum orbiculare).
Activity with respect to yeast-like mushrooms, depending on their species, may be a fungicidal or fungistatic one.
Terbinefin does not affect the metabolism of hormones or other medicines.
The minimum overwhelming concentration for Trychophyton Rubrum is 0.001-0.06 μg / ml. With onchomicosis of the brushes, the effectiveness of treatment is 95%, during onchomicosis of the stop - more than 90%. With chronic smooth skin dermatophys, remission is achieved in 75-95% of patients. The subjective improvement in the treatment of the progressive candidosis of smooth skin and the lesion of large and interdigital folds, paronymics caused by Candida albicans and resistant to therapy nistatin, leviversity, in combination with clotrimazole and miconazole, comes 3-4 days, and the complete resolution of the process - after 3-5 weeks

Pharmacokinetics

For local application Absorption - less than 5%, has a minor system action.

Indications for use

Cream Terbinefin.it is used for fungal skin diseases caused by sensitive pathogens (trico, microsporement, epidermofiytium, rubreditilation, candidiasis of the skin), multicolored deprived.

Mode of application

Terbinefin creamapply externally. Adults and children over 12 years old: the cream is applied to the affected areas of the skin and adjacent areas with a thin layer, slightly rubbing, 1 or 2 times a day. The duration of the treatment has depends on the testimony and severity of the course of the disease. The course of treatment is an average of 2-4 weeks. Duration and multiplicity of application: Dermatomicosis of the body, legs, stop - 1 time per day for 1 week; Candidiasis of the skin - 1-2 times a day for 1-2 weeks; Multicolored deprived - 1-2 times a day for 2 weeks.

Side effects

When using cream Terbinefin.such may arise side effects, as itching and burning skin, hyperemia in the place of application, allergic reactions are possible.

Contraindications

:
Contraindicated apply cream Terbinefin.with increased sensitivity to terbinefin or any of the inactive ingredients included in the preparation.
With caution: renal / liver failure, alcoholism, inhibition of bone marrowing, tumors, metabolic diseases, occlusive limb vessel diseases, pregnancy, period breastfeeding, children's age up to 12 years old (lack of sufficient clinical experience).

Pregnancy

:
In experimental studies of teratogenic properties Terbinafina It was not revealed. To date, it has not been reported on any defects in the use of terbinafin cream. However, since clinical experience The use of terbinefin cream in pregnant women is very limited, it should be applied only by strict indications.
Terbinefin stands out by S. breast milk. However, in the case of applied by a nursing material, a small amount of active substance is absorbed through the skin, therefore the adverse effect on the baby is unlikely.
Cream cannot be applied to the mammary glands during breastfeeding period.
When pregnancy and in the period of breastfeeding, it is used only if the estimated benefit for the mother exceeds the potential risk to the fetus or child.

Interaction with other medicines

Terbinefin.it can influence the clearance of drugs, in the metabolism of which the system of the P450 cytochter takes part ( oral contraceptives, Cyclosporine, Tolbulamd). It provides biotransformation of H2-histamine blockers, increasing their concentration in blood plasma. Rifampicin increases the clearance by 2 times, and terpheneadine slows down its excretion from the body. In patients taking terbinafin and in parallel using oral contraceptives, a violation of the regularity of the menstrual cycle may be observed.

Overdose

:
With external use of cream Terbinefin.overdose is unlikely.
Symptoms at a random reception inside: headache, nausea, gastralgy, dizziness, stripped urination, rash.
Treatment: Activated coal, if necessary, symptomatic supporting therapy.

Storage conditions

In the place protected from light, at a temperature not lower than 0 ° C and not higher than 25 ° C. Do not allow freezing.

Form release

Terbafin creamfor external use of 1% 15 g in aluminum tubes.

Structure

:
100 g terbafin creamcontains: Active substance: Terbinefin hydrochloride - 1.0 g. Adewants: Water purified, benzyl alcohol, distilled Griercerol, Vaseline, Stearinic acid, Emulsifier No. 1, Triethanolamine.

Additionally

:
Irregular use or early termination of treatment increases the risk of recurrence. If after 2 weeks of treatment, there is no improvement in the condition, it is necessary to re-identify the causative agent of the disease and its sensitivity to the drug. In the process of treatment, it is necessary to comply with general hygiene rules for the prevention of reinfection (through underwear, shoes). Avoid hitting the mucous membrane of the eyes, nose, mouth.
Impact on the ability to driving vehicles and control mechanisms
During the treatment period, it is possible to control vehicles and engage in other potentially hazardous species Activities requiring increased concentration of attention and speed of psychomotor reactions.

Main settings

Name:

Terbinefin cream

Consider the features of Mazi terbinafin from fungus, instructions for use to it. Let us dwell on the key characteristics, advantages, rules of application. We also specify the main analogues. Be sure to remember not only about the testimony for use, but also contraindications. Everyone willing will be able to compile an objective idea of \u200b\u200bthe modern tool from the nail fungus - Mazi Terbinafin.

Treatment

Fungal lesions are now widespread. Nobody is insured against these diseases. Unfortunately, the fungus is often transmitted from carriers. Sufficient touch to infect because of the microparticles on the skin. Despite the rapid development of the market of various pharmaceutical preparations, the emergence of numerous new products for maintaining hygiene, the number of ill fungus is growing steadily.

The use of ointment terbinafin will make rid of fungal lesions. It is ointment that specialists are recommended as the most efficient, safe remedy for mikosa with a minimum set of contraindications.

Also in pharmacies are widely represented analogues of ointment terbinafin. We give several drugs to the list, we will stop at some some more details. Here are the most famous and quite affordable funds:

• spray lamp;
• gel, cream lamizil;
• Thermal;
• Terbix;
• Expin;
• Atiphin;
• Terbinox;
• Fungoterbin.

Two main competitor terbinafin

Dermatologists note that honored trust and high demand uses the famous drug - Tebikur. He is recognized effective, quite safe tool. Thebikur copes well with the nail fungus, even when the disease is very launched. The huge advantage of the drug is that it does not have to remove the nail records. However, to achieve an optimal result will have to undergo a full course of treatment, which lasts 5-6 weeks. In addition, this ointment is designed exclusively to combat the fungus nail, and it does not have a proper influence on the mucous membranes.

Another famous analogue of terbinafina - Onykhon. The composition of Mazi is just included in the role of the basic component of terbinafin. The means heals the fungus in two weeks, but the exact duration of the course will depend on the type of disease.

• Candidiasis of the skin will cure in 2-4 weeks.
• On the fight against mycosis, the scalp will leave for 4 weeks.
• Dermatomycosis of the body, the heads will pass only after 3-4 weeks.
• Dermatomikosis Stop requires therapy for 2 - 6 weeks.

The price of all drugs is quite democratic. A tube of the very terbinefin can be purchased for only 80-90 rubles.

Terbanfin ointment: what is the drug

Terbinefin is effective tool aimed action against fungus. It destroys the pathogenic environment, actively struggles with fungus and eliminates the effects of the disease. The drug acts on mold and yeast, dimorphous fungi, as well as dermatophytes. It can be argued that the tool is effectively fighting with all the famous science pathogenic types of fungal infections for a person.

Base active Component As part of ointments - terbinafin hydrochloride. It successfully affects all cytoplasmic membranes of fungal cell cells, while the synthesis of Ergosterina disrupts. As a result, inside the cells, the accumulation of the squalene is stimulated, ensuring the complete destruction of the fungus. It is extremely important that with the help of terbinefin in the human body, the natural processes of hormone metabolism are not violated. In this regard, we can talk about the safety of the drug, the absence of side effects.

The tool is practically not absorbed, not absorbed into lymph, blood and tissue. It is justicely affecting the fungus, without concentrating in the tissues or body fluids and is never delayed anywhere. Some are interested, what are the differences in cream and ointment terbinafin. Experts note that drugs in different formats have approximately the same composition, but the concentration, auxiliary components differ. Dermatologists recommend using terbinefin ointment as the most effective means.

What treats ointment: Successful struggle against fungus of all types

We learn from which the ointment of terbabin from the nail fungus helps.

• It is used to combat yeast skin infections. They provoke a candida fungus that causes toughness, Candidia Rade, Nasal cavity, as well as outdoor genital organs. This is due to the destructive effect on the mucous tissue.
• Heals ointment fungus on nails, on fingers.
• Terbanfin ointment copes with deprive branvoid type. It is extremely important that the ointment possesses a universal action: it copes not only with the fungus of nail plates, but also eliminates dermis dermis, in particular, on the elbows, in the footsteps.
• Effectively treatment of multicolored lingahitting the horn layers of the epidermis.
• The terbinafin is widely used for therapy onichomicosis - Defeat of nail plates.

But it is not enough to determine the testimony for use.

Council. To achieve maximum results, go through the course of therapy, it is necessary to contact a dermatologist for advice. It will hold an appropriate examination, the inspection will determine the optimal methods of treatment, it may be prescribed additional drugs to combat fungus, leaving terbinafin as a fixed assessment.

Operating principle

Ointment successfully copes with an overwhelming majority caused by fungal hair and nail infections, skin. At the same time, the risk of recurrences decreases to a minimum. Here is the algorithm of the drug:

1. Membrane fungus is destroyed in a short time.
2. Ergosterine ceases to be produced.
3. The amount of squalene increases sharply.

Important. In accordance with the data obtained with thorough laboratory research and clinical trials, more than ninety percent of the patients managed to cure fungal infections, it is using terbinefin.

Key indication for the use of ointments - identifying fungal infection in the body. Dermatologists note that the appearance of redness, a small itching on the skin does not become a valid reason for the termination of ointment. It is almost harmless, so there is no need to cancel the drug.

Apply the ointment correctly: instruction

In special attention, instructions for use for ointment terbinafin needed. Consider key points. Then, if necessary, the patient will be able to even independently use the drug to combat fungus.

Apply an ointment on the skin by the rigorous massaging movements. The layer should be thin, uniform over the entire area of \u200b\u200bthe problem zone. There is such a procedure during the day twice. It is advisable to do it in the evening, morning time. Before it, the skin should be carefully cleaned, and then dry well.

When carried out treatment of nail fungusMazi draws literally seconds. It is enough to squeeze a little means on the pillow of your finger, and then launched into the nail plate. Be sure to remember that the tool must absorb well in the nail. At least 20 minutes you need not to wet the nails, do not touch them. For example, it is impossible to wash the dishes, take a shower or put on gloves. The optimal solution is to just keep your hands half an hour in full.

Council. When there is a need to eliminate diameters, folds are first thoroughly washed with warm water. Then they must be dried. You can use a soft towel. Most often, diaperships begin to appear in the area of \u200b\u200binterpallated folds, the groove zone, on areas under the milk glands of the owners of a big breast.

After a few days later, in the overwhelming majority of cases, there is a positive result of the use of the drug. However, the processing of affected areas must be continued because need effect only coucia therapy brings. Otherwise, if the treatment is interrupted with the disappearance of external symptoms, the fungus will begin to multiply again. Procedures must be carried out regularly, according to its clear schedule without disturbing it.

Experts claim that it is possible to use terbinafin ointment and children. However, for them accurate dosageThe schedule of procedures can determine the dermatologist exclusively. In addition, it will be necessary to carry out a small testing to make sure that the child has individual intolerance to the drug, allergic reactions.

Sometimes it happens: the coursework is completely passed, but the symptoms of the disease remain. The fungus again continues to hit mucous, skin or nail plates. In this case, you should again contact the dermatologist, pass the appropriate examination, pass the tests. Probably needed additional treatment.

Contraindications

There are ointment from fungal infections and some contraindications. They should be paid attention to them:

• It is undesirable to use ointment in the period of tooling the baby, lactation.
• Allergies or individual intolerance of the components of the drug immediately imposes a ban on application.
• Violation exchange processes in organism.
• Drinking alcoholic beverages.
• Heavy liver diseases, kidneys, urinary system organs.
• It is impossible to use the ointment for children under three years and patients with a body weight of less than 20 kilograms.
• Also, ointment is prohibited in strokes and embolism, thrombosis.

Some experts note that during pregnancy, breastfeeding, the use of ointments is not as dangerous, but it is still preferably to avoid it.

Be careful, watch your health. Terbinefin will help defeat the fungus.