Senade: instructions for use, analogues and reviews, prices in Russian pharmacies. Senade - how to take with constipation, for cleansing and losing weight? Metabolic disorders cause

01.08.2020 Sport

Senade (sennosides A and B) - a contact laxative plant origin produced in the homeland of Mahatma Gandhi and Jawaharlal Nehru. This is another drug from a countless number of Indian generics that have firmly established themselves on Russian shelves and are seriously competing with more expensive original drugs, not to mention domestic ones, for which, to be honest, the heart of the average Russian consumer of medicines does not always lie. Moreover, the Senade does not have a domestic analogue. Contact laxatives are by far the most popular of all groups of drugs that help unload a heap of gastrointestinal problems and bring a revolutionary revival to the period of stagnation established in the gastrointestinal tract. Medicines based on senna have been familiar to Aesculapius for centuries: their popularity is due to their therapeutic efficacy and relative cheapness. As a medicinal plant raw material for the production of senna preparations, senna leaves (cassia) are used, which in the old days, due to logistical features (it got to Russia, bypassing the Egyptian port of Alexandria) was called the “Alexandrian leaf”. Pharmacologically active substances, with which the plant is packed “to the eyeballs”, are represented by sennosides, namely: anthraglycosides, anthraquinones, emodin, aloe-emodin, rhein and other phytocompounds. These substances have a local irritating effect on the chemoreceptors of the large intestine and enhance its peristalsis. The laxative effect begins to manifest itself 8-10 hours after ingestion.

Senade (this drug is available exclusively in tablets) is a standardized dry extract of senna leaves, containing a dose of sennosides verified with jewelry accuracy and devoid of plant "garbage" in the form of resinous and other compounds that can cause unwanted adverse reactions - general weakness, nausea, bloating and spastic colic. Senade sennosides, in addition to stimulating peristaltic contractions and activating the process of emptying the intestines, promote the secretion of water into the intestinal lumen, which increases the volume of its contents and strengthens the reasoned urge to defecate. Sennosides are practically non-toxic and in no way associated with the risk of developing neoplasms in the digestive tract.

The rules for taking senade do not differ in any particular sophistication: 1 tablet 1 time per day (if there is no expected effect, you can add 2-3 more tablets) before going to bed (for adults and children over 12 years old) or half a tablet with the possibility of increasing the dose up to 1-2 tablets (for children 6-12 years old). To select the optimal dosing regimen, it is recommended to take the same dose for at least several days, gradually increasing it (step - ½ tablet). Upon reaching the maximum (3 tablets), you should wait another 3 days and in the absence of defecation, you must consult a doctor without fail. By general recommendations the duration of taking senade should not exceed 2 weeks. In the course of taking the drug, urine may surprise with a bizarre colors from red-lilac to yellow-brown. You should not be afraid: this is the normal state of affairs.

Pharmacology

Laxative of plant origin. It has a laxative effect that occurs after 8-10 hours. The laxative effect is due to the effect on the receptors of the large intestine, which enhances peristalsis.

Pharmacokinetics

In accordance with the International Convention (EMEAHMPWG11/99) when conducting clinical research herbal preparations do not require an isolated study of pharmacokinetic parameters.

Release form

Tablets from brown to dark brown, interspersed, flat, round, with bevelled edges, with the word "CIPLA" embossed on one side and a break line on the other.

Excipients: lactose - 23.07 mg, starch - 43.56 mg, methyl parahydroxybenzoate - 0.04 mg, microcrystalline cellulose - 15 mg, talc - 11.13 mg, magnesium stearate - 0.93 mg, sodium lauryl sulfate - 0.93 mg, carmellose sodium - 2 mg.

20 pcs. - blisters (2) - packs of cardboard.
20 pcs. - blisters (3) - packs of cardboard.
20 pcs. - blisters (25) - cardboard boxes.

Dosage

The drug is administered orally, as a rule, 1 time / day in the evening before bedtime, washed down with water or some drink.

Adults and children over 12 years old - 1 tab. 1 time / day In the absence of effect, the dose can be increased to 2-3 tablets.

Children aged 6-12 years are prescribed 1/2 tab. 1 time / day and, if necessary, increase the dose to 1-2 tab.

In the process of selection, the same dose should be taken for several days and gradually increased by 1/2 tab. If, after reaching the maximum dose, bowel movements do not occur within 3 days, you should consult a doctor.

Overdose

Symptoms: diarrhea leading to dehydration.

Treatment: Increasing fluid intake is usually enough to compensate for the loss of fluid and electrolytes. In some cases, replacement of the loss of fluid and electrolytes with the help of intravenous infusions of plasma substitutes is required.

Interaction

With prolonged use of Senade ® in high doses, it is possible to increase the action of cardiac glycosides and influence the action of antiarrhythmic drugs due to the possibility of developing hypokalemia.

With simultaneous use with thiazide diuretics, corticosteroids, licorice root preparations, the risk of developing hypokalemia increases.

Side effects

From the side digestive system: possible colicky abdominal pain, flatulence; with prolonged use, especially at high doses, melanin deposits in the intestinal mucosa, nausea, vomiting, diarrhea are possible.

On the part of metabolism: with prolonged use, especially at high doses, there may be disturbances in water and electrolyte metabolism, deposition of melanin in the intestinal mucosa.

From the urinary system: with prolonged use, especially at high doses, albuminuria, hematuria, urine discoloration are possible.

From the side of the central nervous system: with prolonged use, especially at high doses, convulsions, fatigue, confusion are possible.

Dermatological reactions: with prolonged use, especially at high doses, a skin rash is possible.

From the side of cardio-vascular system: With prolonged use, especially at high doses, vascular collapse is possible.

Indications

constipation caused by hypotension and sluggish peristalsis of the large intestine;
stool regulation for hemorrhoids, proctitis, anal fissures.

Contraindications

spastic constipation;
intestinal obstruction;
abdominal pain of unknown origin;
strangulated hernia;
acute inflammatory diseases abdominal cavity;
peritonitis;
gastrointestinal and uterine bleeding;
cystitis;
violations of water and electrolyte metabolism;
hypersensitivity to the components of the drug.

With caution prescribed for diseases of the liver and / or kidneys, during pregnancy, during breastfeeding, in conditions after abdominal operations.

Application features

Use during pregnancy and lactation

Caution should be given to Senade ® during pregnancy and during breastfeeding.

Application for violations of liver function

Be wary appoint in diseases of the liver.

Application for violations of kidney function

Be wary appoint in diseases of the kidneys.

Use in children

special instructions

After taking the drug, urine may acquire a yellow-brown or red-lilac color.

Pediatric use

The drug is used in children aged 6 years and older.

Constipation for people suffering from them sometimes turn into a real torment. This disease occurs at any age, and the reasons here may be different. Most often it is the wrong diet.

In such cases, the drug Senade tablets are used, application, instructions for use, contraindications, the composition of which is presented further on the site. This tool should be treated with due attention and follow the attached instructions. We will try on www.site to focus your attention on some important points in these recommendations.

Analogues of Senade

Seneid, Glaxena

Release form, composition

The composition of Senade includes an extract of senna holly (in 1 tab. - 93.33 mg) with sennosides A and B (13.5 mg). The drug is produced in the form of round flat brown tablets, interspersed, with a fault line on one side and an embossed inscription CI PL A on the other. Packed in 500pcs. Available in the form of chewable tablets [vanilla or chocolate], chewable lozenges.

pharmachologic effect

Senade is a herbal laxative. The drug acts irritatingly on the receptors of the intestinal mucosa, causing reflex peristalsis, and thus helps to speed up the process of bowel movement and restore its normal functioning. At the same time, it does not affect digestion and does not cause addiction. The action should occur within 8-12 hours from the moment of administration.

Indications

Constipation with hypotension and atony of the gastrointestinal tract, with sluggish peristalsis of the colon. Relief of bowel movements in the presence of hemorrhoids, proctitis, anal fissures or after childbirth, operations.

Application of Senade

How to take Senade tablets is described in the instructions for the drug. Namely: it is administered orally, most often it is an evening reception. Adults and children from 12 years old - once a day (drink after meals before bedtime) one tablet. Washed down with water or other non-carbonated drink. It happens that the effect does not occur for a long time, then the dose is increased to two tablets, in rare cases - up to three per day. If a child has problems from 1 to 6 years old, then you need to take one third of the tablet. After 6 years - half a tablet per day. It is important to remember that the dose of this drug cannot be increased sharply, but increase by half a tablet (for adults).

There have been cases when, despite the instructions for using Senade, the effect of this drug came much faster than expected, so it is important to first consult with your doctor, find out his opinion about the correct use of this laxative for you.

The reason for the necessary consultation with a doctor is the fact that this drug has contraindications.

Contraindications Senade

Instructions for use indicate that the drug should not be taken by patients with intestinal obstruction, abdominal pain of unknown origin; in acute inflammatory diseases of the abdominal cavity, spastic constipation, peritonitis, cystitis; people with disorders of water and electrolyte metabolism, with strangulated hernia, uterine bleeding and in the gastrointestinal tract.

This laxative should be used with caution in pregnant and breastfeeding women who have recently undergone abdominal surgery, children under the age of six, as well as people with liver and kidney failure.

Side effects of Senade

May occur with prolonged use, overdose: hypokalemia, hematuria, proteinuria, spastic abdominal pain, intestinal melanosis, nausea, flatulence, vomiting, urine discoloration; confusion, fatigue, diarrhea, skin rash.

Please note that the instructions for use of "Senade" indicate the risk of hypokalemia, i.e. potassium deficiency, which leads to cramps, muscle weakness, etc. You must also know that if this medicine is used together with thiazide diuretics or preparations with licorice root, the risk of hypokalemia greatly increases.

An increase in the dose of the drug can lead to diarrhea so that the patient will urgently need to take measures to combat dehydration. First of all, this is a plentiful drink and an appeal to a doctor (plasma substitutes may be needed).

The laxative Senade can also interfere with the absorption of tetracyclines.

special instructions

It is best not to use this laxative for more than two weeks. People taking the drug may have yellow-brown or reddish-purple urine. If you do not have a bowel movement after three days of taking Senade, be sure to consult your doctor.

Thanks

The site provides reference information for informational purposes only. Diagnosis and treatment of diseases should be carried out under the supervision of a specialist. All drugs have contraindications. Expert advice is required!

Tablets Senade are a medicinal product made on the basis of vegetable raw materials. Senade has a laxative property, therefore it is used to eliminate constipation in adults and children. Also, a laxative can be used to regulate stool in various pathologies, such as hemorrhoids, proctitis, anal fissures, and obesity. Senade refers to pharmacological group drugs that have a laxative effect by increasing intestinal motility.

Composition, description and release form

The drug Senade today is available only in the form of tablets. There are no other pharmaceutical forms of the drug. Senade tablets are manufactured by the Indian Pharmaceutical Corporation "DR REDDI'S LABORATORIS LTD".

The Senade tablet is colored in various shades of brown, against which small blotches stand out. The tablet is round, flat shape and bevelled edges. On one of the surfaces the word "CIPLA" is squeezed out, and on the other there is a mark - a line along which you can break the tablet. Senade is available in packs of 40, 60 and 500 pieces.

As active ingredient Senade tablets contain an extract obtained from the leaves of the plant senna holly. One tablet contains 93.33 mg of this extract. but active ingredients in the composition of the extract of the leaves of Senna holly are salts of sennosides A and B . In total, each tablet of Senade contains 13.5 mg of sennosides A and B in the form of calcium salts. Usually, the dosage of tablets is indicated precisely by the content of sennosides A and B in it. Therefore, in pharmaceutical guides write that the amount of active substance in Senade tablets is 13.5 mg.

Senade tablets contain the following substances as auxiliary components:

starch;
methyl parahydroxybenzoate;
cellulose microcrystalline;
talc;
magnesium stearate;
sodium lauryl sulfate;
carmellose sodium.

Action and therapeutic effect

Senade tablets have a laxative effect due to active components - sennosides A and B. From a chemical point of view, sennosides A and B are a class of anthraglycoside substances, that is, they contain monosaccharide residues such as glucose, galactose, etc.

Sennosides A and B have a laxative effect due to a direct effect on sensitive receptors located in the mucous membrane of the large intestine. By binding to receptors, sennosides A and B have an exciting effect on the smooth muscle elements of the large intestine, which, in turn, respond to this by increasing the strength, amplitude and duration of peristaltic movements. Thus, Senade tablets increase the peristalsis of the large intestine, due to the active contractions of which its soft emptying occurs.

Against the background of the use of Senade, there is no change in the stool. That is, bowel movements occur in a normal, formed stool, without a tendency to diarrhea. Senade tablets selectively affect the colon, the role of which in the act of defecation is enormous.

In addition, the drug has the ability to normalize the work of the intestine, creating optimal peristaltic contractions. Tablets are not addictive and do not affect the process of digestion of food. This means that Senade can be used to improve intestinal motility for a long time, and then, after the normalization of the function of evacuation of the contents, stop. Withdrawal of the medicine will not cause severe constipation. Also, Senade does not disturb the natural process of digestion, since it only enhances the peristalsis of the colon.

Each Senade tablet contains 13.5 mg of calcium salts of sennosides A and B, which are isolated from senna leaves. This amount of active substances corresponds to 0.6 g of dry powder of senna leaves.

Accurate data on the processes of absorption and excretion of each substance contained in the extract of senna leaves have not been presented to date. There are only data on sennosides A and B. This is due to the fact that, according to the provisions of the International Convention (EMEAHMPWG11/99), it is not necessary to conduct an isolated study of pharmacokinetic parameters for medicines vegetable origin.

How long does it take for the Senade to work?

Typically, Senade tablets cause a bowel movement 8 to 10 hours after ingestion. It is this amount of time that the drug takes to activate the receptors and reflex enhancement of peristalsis, due to which the intestinal contents will move to the rectal ampulla and cause the urge to defecate. After taking Senade, a person's stool is normal.

You can slightly speed up the onset of the medicine by drinking 2 to 3 glasses of warm, lightly salted water. In this case, bowel movements will occur within 6 to 8 hours after taking the tablets.

Indications for use

Since Senade tablets have a laxative effect due to increased peristalsis of the large intestine, their scope is associated precisely with the insufficiency of the contractile activity of the smooth muscle elements of the digestive tract. That is why indications for the use of Senade as a laxative are the following conditions:

Constipation due to hypotension, or sluggish and insufficient peristaltic activity of the colon.
Functional constipation associated with ignoring the urge to defecate, followed by the inability to go to the toilet.
Stool regulation for hemorrhoids, proctitis or anal fissures.

Sluggish intestinal peristalsis often occurs in people who lead a sedentary lifestyle. Unfortunately, in modern conditions, many people are forced to lead a sedentary lifestyle, which is due to sedentary work, and moving around the city by car or public transport. As a result, with normal nutrition and the absence of serious illnesses bodies gastrointestinal tract this category of people develop habitual constipation. In addition, insufficiency of peristalsis is observed in children, pregnant women, the elderly, in bedridden patients or in patients who have undergone surgery. It is with such conditions that Senade copes well, which is recommended as an effective and safe laxative for all people belonging to this category.

The second indication for the use of Senade is the regulation of stool in diseases of the rectum. In these situations, regular bowel movements are necessary. It is unacceptable to postpone or skip a bowel movement, as this can only aggravate the course of the disease. In addition, with such an adjustable stool, it is easier to do small oncoming oil enemas before defecation, which facilitate the passage of feces through the anal sphincter, and eliminate the associated pain syndrome.

Senade - instructions for use (how to take pills for constipation)

Senade tablets are taken orally. As a rule, it is necessary to take the drug once a day, preferably in the evening, before going to bed or half an hour before meals. The tablet should be washed down with a sufficient amount (at least half a glass) of water or any other non-alcoholic drink.

If the drug is taken on its own, without a doctor's prescription, then it is recommended to limit yourself to a short course - to drink pills no longer than 3 to 5 days in a row. Usually it is within 3-5 days that the stool is completely normalized, which no longer requires the use of a laxative. By prescription of a doctor and with regular medical examinations, long-term use of Senade tablets is possible.

Adults and children over 12 years old

The dosage depends on the age of the person and the initial level of activity of intestinal motility. So, children over 12 years old and adults take one tablet once a day. One tablet of Senade is the minimum initial dosage with which the use of the drug should be started. Senade should be taken one tablet at a time for three days. If after this there was no bowel movement, you should increase the dosage by half a tablet, and take one and a half tablets for another three days. Following this algorithm, you can increase the dosage to 3 tablets per day. Do not take more than 3 tablets per day, as this can lead to the development of an overdose. If within three days a person took the maximum dosage of three tablets, but defecation did not occur, then you should consult a doctor.

Children 6-12 years old

Children aged 6 to 12 take half a tablet once a day. For children of this age, the initial dosage is exactly half a tablet, so the child should start giving the drug in such an amount. If Senade is ineffective within two days, you can increase the dosage by another half tablet. The maximum dosage for children 6-12 years old is two tablets.

Interaction with other drugs

The use for a long period of time in combination with cardiac glycosides (for example, Strofantin, etc.) and antiarrhythmic drugs enhances the effects of the latter. Joint application antiarrhythmic drugs and Senade can provoke the excretion of potassium from the body with the development of its deficiency.

In such a situation, intense bowel movements and severe pain in the abdomen of a pregnant woman can provoke strong muscle contractions of the abdominal wall, reminiscent of those during attempts. It is quite clear that tension in the abdominal wall and abdominal pain can result in premature birth or threatened miscarriage. The threat of miscarriage during short periods of pregnancy while taking Senade is also explained by the fact that the tablets increase the tone of the smooth muscles of the uterus.

That is why manufacturers do not recommend that pregnant women take Senade without examination and a doctor's recommendation. Pregnant women can take the drug if constipation does not last long - a maximum of 2 days. However, in this case, it is better to drink more water with the Senade tablet so that it softens a little. stool, facilitating their passage through the anal sphincter. If a pregnant woman has constipation for more than three days, then Senade should be abandoned, since the drug will cause strong contractions of the intestinal muscles, severe spastic pains and a significant increase in uterine tone. Senade can be used prophylactically during pregnancy, for example, in the evening before going to bed, after a long and difficult day, so that a bowel movement is guaranteed the next morning. The dosage of Senade for pregnant women is 1 - 2 tablets per day, which are best taken at night, before bedtime.

Senade for children - how to use

Senade tablets can be used to relieve constipation in children from 6 years of age. It is necessary to give the child a pill along with a glass of water and ask him to drink the medicine well. If necessary, Senade is allowed to be taken by children from the age of 3 years.

The dosage for a child is half a tablet per day, which is best taken in the evening, before going to bed. If within a day after taking half the pill the child did not go to the toilet, then you can give him another half and wait another day. Then you should give the child a whole tablet and wait for a bowel movement for a day. If after that the child does not poop, you should consult a doctor.

For children, the recommended dosage is 0.5 - 1 tablet, and the maximum is 2 tablets per day. It is necessary to start giving the drug to the baby with the recommended dosage, and if it is ineffective, you can resort to the maximum allowable amount. Depending on the duration of the constipation and the age of the child, half or a whole tablet of Senada should be given for the first time. For example, with prolonged constipation, it is better to give the child a whole pill at once, and if this condition occurs for a relatively short period of time, then half is enough. If necessary, you can immediately give the child maximum dose- 2 tablets of Senade. If after taking the maximum dosage during the day there is no bowel movement, then you should consult a doctor.

Senade for weight loss - how to take

Today among pharmaceuticals There are various specialized products designed specifically for weight loss. However, often people try to lose weight with the help of various laxatives. Of course, by clearing the intestines of feces and removing a large amount of fluid and electrolytes from the human body, Senade will reduce weight by several kilograms. Only these lost kilograms consist of fluid, which is vital for the body and various microelements, which are also urgently needed for normal flow. biological processes. Of course, part of the lost kilograms will fall on the stool, which justifiably left the body.

However, if a person wants to really cleanse the intestines and lose weight by removing accumulated feces, then Senade should be taken for 1 to 2 days in a row, and then put it aside. In two days, the drug will remove the accumulated feces, remove the toxins in them and make a person slimmer by a couple of kilograms. Further application Senade for weight loss will only cause dehydration and loss of electrolytes, which is fraught with the development of severe metabolic disorders. But fat deposits will remain in the same place where they were before, since the drug does not contribute to their splitting and excretion.

Nutritionists consider it appropriate to take Senade for the purpose of emptying the intestines only when a person follows a rigid diet with a minimum amount of food, which itself provokes constipation. In such cases, nutritionists recommend taking Senade 1 to 2 tablets twice a week.

Contraindications

Despite the plant origin of Senade, as well as its almost complete safety, the tablets have contraindications for use. Contraindications associated with various states body and gastrointestinal tract, in which it is impossible to increase intestinal motility.

There are absolute and relative contraindications to the use of Senade tablets. In the presence of absolute contraindications, tablets should not be used under any circumstances. And in the presence of relative contraindications, Senade tablets can be used with caution, and under medical supervision over the human condition. Relative and absolute contraindications to the use of Senade tablets are shown in the table:

Absolute contraindications to Senada

Relative contraindications to Senada

Severe sensitivity, intolerance or allergy to tablet components

The period after abdominal surgery

Spasmodic constipation

kidney disease

, should stop using Senade tablets, as they contain milk sugar in their composition.

Side effects

Senade tablets can cause side effects from various systems, since the active active ingredients act on receptors located in the mucous membranes of almost all organs. Most often, side effects are relatively mild, and disappear on their own after discontinuation of the drug, without requiring any additional treatment. Side effects usually appear after long-term use Senade in high doses. The whole range of side effects of tablets from various organs and systems is reflected in the table:

Organ system from which side effects develop	Specific symptoms of side effects
Gastrointestinal tract	colic pain in the abdomen (cramps)
	Flatulence
	Nausea
	Vomit
	Diarrhea

Metabolism	Deposition of melanin in the mucous membrane of the colon (with prolonged use in high doses)
Metabolism	Fluid and electrolyte disturbances, manifested by symptoms such as dehydration, decreased sodium and potassium levels, secondary hyperaldosteronism, ECG changes, muscle weakness
urinary system	Albuminuria (the appearance of protein in the urine)
	Hematuria (blood in the urine)
	Urine discoloration
central nervous system	convulsions
	Fatigue
	Confusion
Leather	Rash
The cardiovascular system	Vascular collapse

Analogues

To date, Senade tablets in the domestic pharmaceutical market have analogues and synonyms. Synonyms are drugs that, like Senade, contain sennosides A and B as an active ingredient. Senade's analogues include drugs that have a laxative effect by increasing peristalsis, but containing other chemical compounds as active ingredients.

So, the following drugs are synonymous with Senade tablets:

Antrasennin - tablets;
Bekunis - dragee;
Herbion Laksana - tablets;
Glaxenna - tablets;
X-Prep - oral solution;
Pursennid - tablets;
Regulax - cubes for chewing;
Senadeks - tablets;
Senadexin and Senadexin-N.S. - tablets;
Senalex - tablets;
Senna - tablets;
Sennalaks - chewable tablets;
Senna extract - tablets;
Tisasen - tablets;
Ex-Lax - chewable lozenges.

The following medicines belong to analogues of Senade:

Agiolaks - granules;
Bisacodyl - rectal suppositories and tablets;
Guttalax - drops;
Dulcolax - rectal suppositories and tablets;
Isafenin - tablets;
Castor oil - capsules and whole oil for oral administration;
Laxigal - drops;
Mucofalk - granules for suspension preparation;
Naturolax - powder for suspension preparation;
Regulax Picosulfate - drops;
Slabikap - drops;
Slabilen - drops;
Fiberlex - powder for suspension preparation;
Phenolphthalein - tablets;
Guttasil - drops.

One tablet contains 93.33 mg hay leaf extract (in terms of sennoside B content calcium salts of sennosides A And IN is 13.5 mg).

The composition also contains excipients: starch, microcrystalline cellulose, lactose, methyl parahydroxybenzoate, magnesium stearate, sodium carmellose, talc And sodium lauryl sulfate.

Release form

Senade is available in 13.5 mg tablets. One blister contains 20 tablets. There are cardboard packs of 2 and 3 blisters and cardboard boxes of 25 blisters.

pharmachologic effect

What is it: it laxative which is of plant origin. After what time it works: after application, the drug begins to act after 8-10 hours, providing laxative effect . This property is possible due to the effect on the receptors of the large intestine, which increases peristalsis.

Indications for use

It is recommended to use Senade tablets, from which the stool normalizes, with which are caused weak peristalsis And hypotension of the large intestine . In addition, the drug is indicated if you have , or stool adjustment required proctitis .

Pharmacodynamics and pharmacokinetics

An isolated study of the pharmacokinetic parameters of herbal preparations is not required in accordance with the International Convention (EMEAHMPWG11/99).

Contraindications

Before taking Senade tablets, you should familiarize yourself with the contraindications for use. The drug can not be drunk with:

strangulated hernia ;
intestinal obstruction ;
spastic ;
abdominal pain of unknown origin;
peritonitis ;
acute inflammatory diseases of the abdominal cavity;
violations of water and electrolyte metabolism;
with uterine and gastrointestinal bleeding;
in case you have hypersensitivity to the components present in the composition of the tablets.

It is also correct to take tablets with caution in case of kidney and / or liver diseases, after abdominal operations, as well as during or during the lactation period.

Side effects

For the digestive system: colicky abdominal pain is also possible. In case of prolonged use of the drug, it is possible nausea , diarrhea , vomit , as well as the deposition of melanin in the intestinal mucosa. This is especially true when using the drug in high doses.

For the urinary system: possible discoloration of urine, hematuria , as well as albuminuria .

For the cardiovascular system: may be vascular collapse.

For metabolism: water-electrolyte metabolism may be disturbed.

Dermatological reactions: a skin rash may develop.

Instructions for Senada (Method and dosage)

A laxative is taken orally once a day at bedtime with a drink or water.

Instructions for use Senade is divided into two categories:

dosage for children over 12 years old and adults - one tablet once a day. If there is no effect, then you can increase the dose of the drug to 2-3 tablets at a time;
dosage for children from 6 to 12 years - take the drug once a day, half a tablet. If necessary, you can increase the dose to 1-2 tablets at a time.

While the dosage selection process is taking place, you need to use the same dose for several days, gradually increasing it by half a tablet. If the maximum dosage is reached, but defecation does not occur within 3 days, then you need to consult a doctor.

Overdose

In case of overdose occurs, which leads to dehydration .

Increased fluid intake may be sufficient as a treatment to help compensate for the loss of electrolytes and fluids in the body. It may be necessary to replenish fluids in the body with an intravenous infusion plasma substitutes .

Interaction

In the case of long-term use of the drug at a high dosage, there may be an increase in the effect cardiac glycosides , as well as influencing the actions of antiarrhythmic drugs, which may lead to the development hypokalemia .

In the case of simultaneous use of the drug Senade with corticosteroids, thiazide diuretics and licorice root preparations, the risk of developing hypoepliemia increases.

Senade is an effective laxative that contains only herbal ingredients. It well eliminates constipation in children and adults. It is also used in the regulation of stool and various pathologies. Instructions for use of the drug Senade are listed below.

Senade tablets are manufactured by the Indian Pharmaceutical Corporation Dr. Reddy's Laboratories Ltd. ("CIPLA LTD").

Release form and composition

To speed up the process, you can drink 2-3 glasses of salted warm water. With this action, emptying will begin around 6-8 hours.

Side effects

The drug Senade can cause side effects from different systems. All active ingredients act on receptors that are located in the mucous membranes of all organs.

Video:

Less often, any side effects are expressed by symptoms. Symptoms side effects appear after taking the pills for a long time and in large doses.

Contraindications

Senade, like most laxatives, has both positive and non-negative aspects. Contraindications are associated with different conditions of the gastrointestinal tract. There are relative and absolute contraindications for the use of tablets. With absolute contraindications, tablets should not be taken in any case. With relative contraindications, tablets should be taken with some caution.

Dosage and overdose

The drug is intended for oral use.

Adults take one tablet daily at bedtime with a glass of water.
Dosage for children over 12 years old - 1 tablet per day. If there are no contraindications, the dose can be increased to two or three tablets.
Children from 6 to 12 years old - half a tablet per day. With the severity of symptoms, the dose is increased to two tablets.

When treating, you need to take one dose for several days and increase the dose gradually. If with such changes there is no reaction and there is no result, it is necessary to consult a doctor.

The main indicator of an overdose of the drug Senade is intractable diarrhea.

After it, the body is severely dehydrated. To replenish the lack of fluid in the body, you should drink plenty of water, at least three liters.

Interaction with other drugs

When using Senade with other medicines enhances the effect of the latter.

Especially if taken together with cardiac glycosides and antiarrhythmic drugs.

If you mix Senade and the last type of drugs, it is possible to remove potassium from the body, with the development of its deficiency.

The development of potassium is facilitated by taking the same drugs as Senade and diuretics, glucocorticosteroid and licorice root.

The drug in combination with other medicines will reduce their effect, especially if they have a prolonged effect and are slowly absorbed.

The drug Senade only provokes and accelerates the movement of feces, but does not affect the state of bowel movements, so the sensations with it can be the most unpleasant. This is due to the fact that the feces are in the intestinal lumen for a long time and water is sucked out of them, and the feces become dry and hard.

Such dry and hard feces begin to move towards the anal exit under the influence of the drug. Since such an advancement and exit itself is very difficult and painful, it greatly reduces the intestines, which can cause spasmodic pain in a woman during pregnancy.

It is these pains that are very dangerous and unpleasant. They can provoke strong muscle contractions of the abdominal wall, which can be compared with attempts.

It is clear that such contractions can lead to premature birth or miscarriage. The drug is also not recommended during the entire pregnancy, and in the early stages. Senada is allowed to take if constipation lasts no more than 2 days. But in this case, in addition to tablets, you need to drink a large amount of water, so that softening of the feces follows and facilitates their exit.

If the constipation is prolonged, then this drug better not to use.

For prevention, Senade can be taken, preferably in the evening, so that the stool returns to normal in the morning.

For pregnant women, the dose of the drug is one or two tablets per day, depending on the severity.