Rinza - instructions, application, reviews. "Rinza" (powder): reviews. "Rinza" (tablets): reviews of doctors and buyers, instructions for using Rinza to take before meals or after

19.07.2020 Recipes

For the treatment of colds, acute respiratory viral infections and flu in children, parents strive to use effective and safe drugs. Medicines, which include several components that gently relieve various symptoms of the disease, are very popular. How to treat children with Rinza drugs, read our article.

Release form

Several multicomponent anti-flu and cold remedies are produced under the Rinza trademark. These are Rinza pills, Rinzasip and Rinzasip for children powder sachets.

Rinsasip Kids has a raspberry flavor, while the adult powder has a taste of black currant, lemon and orange.

Compound

Each Rinza tablet contains 30 mg of caffeine, 500 mg of paracetamol, 10 mg of phenylephrine hydrochloride and 2 mg of chlorphenamine maleate.

Caffeine is a natural psychostimulant found in many widespread drinks - coffee, tea, cola. In the body, caffeine stimulates the central nervous system, which is why it is included in medicines for headaches and migraines.

Paracetamol is a well-known substance used in drugs for lowering body temperature, anti-cold combined drugs. Phenylephrine hydrochloride has a vasoconstrictor effect, and chlorphenamine maleate has an antihistamine effect. Together, they quickly relieve the symptoms of flu and colds, relieving the condition of the sick.

As auxiliary components in the tablets, corn starch, magnesium stearate, talc and Ponso 4R crimson dye are used.

One sachet of powder for children contains 100 mg of ascorbic acid, 280 mg of paracetamol, and 10 mg of pheniramine maleate. As you know, ascorbic acid is a source of vitamin C, and pheniramine maleate is an anti-allergic agent.

Additionally, add to the baby powder:

  • natural dye and flavor;
  • sucrose and the sweetener aspartame for flavor, since ascorbic acid is very acidic;
  • magnesium citrate, which promotes cellular energy.

The powder for preparing a hot drink for children over 15 years old has a different composition: it contains caffeine, it is fortified with vitamin C and the corresponding flavors and sweeteners. In addition, an adult drink made from a single packet contains much more paracetamol - 750 mg.

Operating principle

Rinza tablets have antipyretic and analgesic effects due to the content of paracetamol. The anti-allergic effect of chlorphenamine also helps to relieve edema, including those caused by seasonal allergies, for example, to the pollen of some plants. Caffeine stimulates the central nervous system, invigorating and improving overall well-being.

Children's "Renzasip" contains ascorbic acid, which is a source of vitamin C and quickly improves the condition of the child.

Indications

Rinza preparations, regardless of the form - tablets or powder - are used to treat colds, acute respiratory infections, acute respiratory viral infections, influenza, including if these diseases occur with an increase in body temperature, fever, chills, head and joint pain, strong current or nasal congestion ... Helps "Rinza" and "Rinzasipkids" for colds or allergic rhinitis.

At what age is it prescribed?

Rinza tablets and powder for preparation of the Rinzasip drink are used in the treatment of children over 15 years of age. For children from 6 years old, you need to use Rinzasip-kids powder with raspberry flavor.

Doctors do not recommend giving children half or a quarter of the Rinza tablet, as well as some of the powder from the adult packet, since they contain caffeine, which is not recommended for children due to its effects on the central nervous system. Secondly, it is difficult to determine the dosage of the drug, which can lead to symptoms of side effects or overdose.

If the child is already 5 years old, if it is impossible to carry out other treatment, you can give him Rinzasip Kids drink. For a baby 3 years old, the dosage of paracetamol contained in the drink will be very large.

If the child is small, and there are no medicines with special children's dosages at hand, there is no need to give him adult medicines. This can aggravate the baby's condition.

Contraindications

There are absolute and relative contraindications to the drugs Rinza, Rinzasip and Rinzasip-kids.

So, baby powder is not used to treat children under 6 years old, as well as if the child has an individual sensitivity to one or more of the components of the drug. It is forbidden to take "Rinza" by children who have severe liver and kidney dysfunctions. In addition, Rinzasip Kids are not given to children with certain blood disorders.

In no case should Rinza-kids be given to children who are already taking medications containing paracetamol, since one packet contains a dose of this substance, which, if exceeded, could lead to an overdose.

Relative contraindications include:

  • diabetes mellitus - due to the content of sucrose, fructose, sweeteners in the preparation;
  • a stomach or duodenal ulcer;
  • some liver diseases;
  • taking medications that can adversely affect the function of the drug.

The drugs "Rinza" and "Rinzasip", approved for use from the age of 15, are not given to children with diabetes mellitus, high blood pressure... With caution, the agent is prescribed for children suffering from bronchial asthma, some blood diseases, renal failure.

Side effects

Among the possible side effects of the drug, the manufacturer lists allergic reactions, such as rashes and hives. The child may complain about headache, nausea, dry mouth.

These symptoms do not appear in all children, but only in rare cases. As a rule, the reason is individual sensitivity to the components or exceeding the dosage.

But whatever the reason, if the parents notice one or more of the listed symptoms, even if they do not associate their appearance with taking medication, then it is better to seek medical help.

With prolonged treatment with the drug, clinical tests can reveal anemia - an insufficient level of hemoglobin in the blood, leukopenia - a decrease in the level of leukocytes in the blood, and other disorders.

Instructions for use

Rinza-kids is very easy to use for children. The powder from one bag must be dissolved in 200 ml, which is equal to one standard glass of water.

The instructions for using the powder for preparing a drink for children contains the following recommendations.

Children from six to ten years old can be given a drink from one package no more than twice a day, children from 10 to 12 years old - one package three times a day. From 12 years old, you can take one packet up to four times a day.

In this case, the interval between doses is at least 4 hours., and the general course of treatment is no more than five days in a row.

From 15 years old, you can give adult dosages of the drug - in tablets or powders. Tablets are taken one to 5 a day, if necessary, for a course of no more than five days, a drink for adults - one packet no more than four times a day. The interval between doses is from 4 to 6 hours.

Overdose

Most often, symptoms of exceeding the maximum allowed dose of paracetamol appear, since other components are contained in the drug in smaller proportions.

Signs such as nausea, vomiting, abdominal pain, increased sweating, and general malaise appear. Such symptoms can appear on the first day after an overdose.

If you suspect an overdose, you must:

  • seek medical attention;
  • rinse the stomach in the first 2 hours;
  • no later than 6 hours - give the child activated charcoal.

Also, within 72 hours, symptoms of liver failure may appear, which requires immediate hospitalization and treatment in a hospital setting.

Interaction with other drugs

The drugs "Rinza" and "Rinzasip" can have an effect on the effectiveness of other drugs when taken simultaneously. So, they enhance the effect of diuretics.

Terms of sale and storage

Rinza and Rinzasip are available over the counter without a prescription. Store packages with medicines in a dry and cool place, the optimum temperature is up to 25 ºС. It is important that the medicine is out of reach of children. The shelf life is 3 years.

On average, people get colds 2-3 times a year. It is especially easy to catch a cold during the fall and winter period. How to deal with the disease? Among the large number medicines takes a worthy place Rinza... How and can it be taken during pregnancy and children, how to drink powder, what are the indications, contraindications for taking the drug, is there inexpensive analogues? Details are in our article.

Indications for Rinza's use

What helps Rinza? It, according to the instructions for use, is prescribed at the first symptoms of ARVI, influenza and other colds and infectious diseases.

Here is a list of indications for which Rinza is prescribed as:

  • antipyretic
  • psychostimulating,
  • antihistamine,
  • analgesic.

Rinza, according to the instructions, helps with:

  • pain (headache, dental, muscle and joint pain),
  • acute rhinitis, sinusitis, rhinopharyngitis,
  • burns and injuries,
  • neuralgia, myalgia, arthralgia.

For those for whom the use of tablets for various reasons is impossible, analogs are prescribed in a different form (say, powder).

Contraindications for use

The instructions for use clearly indicate that Rinza and Rinzasip during pregnancy and the child are contraindicated.

Here is a list of other contraindications in the form:

  • sensitivity to drug components,
  • hypertension,
  • atherosclerosis,
  • severe diabetes mellitus,
  • taking tricyclic antidepressants, MAO inhibitors, drugs, which contain the same components as in Rinze(if these or other drugs are indicated, you should consult a doctor).
  • hepatic and renal failure,
  • glaucoma,
  • hyperplasia of the prostate,
  • diabetes,
  • thyrotoxicosis, etc.

During the course of treatment with the help of Rinz, it is not advisable to drive vehicles, perform work with increased concentration of attention, where a quick psychomotor reaction is required.

Side effects can be observed from the side:

  • central nervous system (dizziness, falling asleep or hyperexcitability),
  • cardiovascular system (increased pressure, tachycardia),
  • digestive system (vomiting, nausea, dry mouth, epigastric pain, impaired liver function),
  • vision (increase intraocular pressure, mydriasis, paresis of accommodation),
  • hematopoietic system (anemia, agranulocytosis, aplastic anemia, thrombocytopenia, methemoglobinemia, hemolytic anemia, pancytopenia),
  • urinary system (urinary retention, papillary necrosis of the kidneys),
  • respiratory system (bronchial obstruction).

Overdose: in acute, nausea, vomiting, diarrhea, increased sweating may appear; with chronic, severe liver dysfunctions are observed,

Rinza tablets and powder composition

1 tablet Rinses contains basic and additional substances.

Here is a list of the main ones:

  • 10mg phenylephrine hydrochloride
  • 30mg caffeine
  • 2mg chlorphenamine maleate.

List of additional substances:

  • magnesium stearate,
  • sodium methyl parahydroxybenzoate,
  • corn starch,
  • sodium carboxymethyl starch,
  • colloidal silicon dioxide,
  • povidone (K-30),
  • talc,
  • the dye is crimson.

Release form - tablets and powder.

Instructions for use of the Rinza tablet

Tablets Rinza taken orally. The instructions say that single dose for adults and children from 15 years old - 1 tab. (maximum - 2, but not more than 4 pieces per day). The frequency of admission is 3-4 times a day. Take within 5 days.
Drink 1.5 hours after meals with the correct amount of water.

Rinzasip

  • It is taken internally. Adults drink sachets 3-4 times a day. The intervals between doses are 4-6 hours.
  • Take no more than 4 sachets per day for 5 days.
  • A sachet of powder dissolves in a glass of hot water; after stirring, drink (adding honey, sugar if desired).

Instruction for children

  • According to the instructions, children under 15 years old this drug not discharged. A child who has reached this age is prescribed 1 sachet 3-4 times a day (no more than 4 pcs.). The interval between doses is 4-6 hours.
  • The course of treatment is no more than 5 days.
  • The powder is poured over with warm water, dissolved and given to the child.

Rinza Lorsept

Rinza Lorsept: antiseptic, lozenges (with lemon, orange, blackcurrant flavor).

  • Shown: locally in ENT practice for infectious and inflammatory diseases of the oral cavity and pharynx (pharyngitis, tonsillitis, laryngitis, hoarseness, etc.) and in dentistry (for thrush, gingivitis, stomatitis).
  • Action: anesthetic, anti-inflammatory, analgesic, antifungal, bactericidal;
  • Side effects: expressed allergic reactions.
  • In case of overdose: there may be vomiting, diarrhea, nausea.
  • Application: dissolve for adults on a tablet every 2-3 hours (no more than 8 tablets per day).
  • A course of treatment- 5 days.

The effect is noticeable in initial stages diseases. If symptoms persist after 3 days, you should contact the clinic.

There are no indications for use by children and during pregnancy. Cannot be consumed Rinzu with special sensitivity to the components of the drug, exceed the dose indicated in the instructions. Drink with caution in case of epilepsy, impaired cardiac conduction, shock, impaired liver function, patients with diabetes mellitus, with a hypocaloric diet.

Rinza Vitamin C hotsip

  • Shown: for symptomatic treatment of colds, flu, ARVI, colds accompanied by fever, impaired nasal breathing, headache, runny nose, sneezing and lacrimation, with inflammation paranasal sinuses nose.
  • Action: analgesic, antipyretic, analgesic, vasoconstrictor, anti-inflammatory.
  • Not shown: with hypersensitivity to the components of the drug, high blood pressure, tachycardia, thyrotoxicosis, severe liver or kidney dysfunction, hyperthyroidism, diabetes, heart disease.
  • In case of overdose: vomiting, nausea, anorexia, abdominal pain, sweating, hepatonecrosis may develop.
  • Side effects: Rinza well tolerated, but in some cases side effects are expressed by dry mouth, impaired accommodation of vision, urinary retention, increased excitability(more often in older people); rarely, side effects are expressed by nausea, vomiting, abdominal pain, tremors, insomnia, headache, convulsions, allergic reactions, leukopenia, renal colic, heart rhythm disturbances.
  • Application: Diluting the powder Rinses in a glass of hot water, the solution is drunk 3 times a day with an interval of at least 4 hours. The course is 5 days. In case of impaired renal function, the interval between doses is increased to 8 hours.

It is necessary to be treated immediately, as soon as the first signs of the disease appear. It is better to give up alcohol, which enhances the sedative effect. Rinza, which is dangerous when driving and working with mechanisms.

In this article, you can read the instructions for use medicinal product Rinza... Reviews of website visitors - consumers of this medicine, as well as opinions of doctors of specialists on the use of Rinza in their practice are presented. A big request is to actively add your reviews about the drug: did the medicine help or did not help get rid of the disease, what complications were observed and side effects, possibly not declared by the manufacturer in the annotation. Rinza's analogs in the presence of available structural analogs. Use for the treatment of symptoms of colds, flu and SARS (runny nose, fever and sore throat) in adults, children, as well as during pregnancy and breastfeeding. Composition of the preparation.

Rinza - combination drug.

Paracetamol has analgesic and antipyretic effects. Reduces pain associated with colds - sore throat, headache, muscle and joint pain, reduces fever.

Phenylephrine is an alpha1-adrenergic agonist. Has a vasoconstrictor effect, reduces edema and hyperemia of the mucous membranes of the upper sections respiratory tract and paranasal sinuses.

Chlorphenamine - a blocker of histamine H1-receptors, has an antiallergic effect, reduces swelling and hyperemia of the mucous membranes of the nasal cavity, nasopharynx and paranasal sinuses, eliminates itching in the eyes and nose, reduces exudative manifestations.

Caffeine has a stimulating effect on the central nervous system, which leads to a decrease in fatigue and drowsiness, and to an increase in mental and physical performance.

Compound

Paracetamol + Caffeine + Phenylephrine hydrochloride + Chlorphenamine maleate + excipients.

2,4-dichlorobenzyl alcohol + Amylmetacresol + excipients (Rinza Lorsept).

2,4-dichlorobenzyl alcohol + Amylmetacresol + Lidocaine hydrochloride monohydrate + excipients (Rinza Lorsept Anesthetics).

Indications

  • symptomatic treatment of "colds", acute respiratory viral infections (including influenza), accompanied by fever, pain syndrome, rhinorrhea;
  • treatment of infectious and inflammatory diseases of the oral cavity and pharynx (tonsillitis, pharyngitis, laryngitis).

Forms of issue

Tablets.

Lozenges (Rinza Lorsept and Lorsept Anesthetics).

Others dosage forms, be it powder or capsule, does not exist.

Instructions for use and reception scheme

Rinza

Adults and children over 15 years of age are prescribed 1 tablet 3-4 times a day. Maximum daily dose- 4 tablets. The course of treatment is no more than 5 days.

Rinza Lorsept

Adults and children over 6 years of age: dissolve 1 tablet every 2-3 hours. The maximum daily dose is 8 tablets.

Rinza Lorsept Anesthetics

Locally. Adults and children over 12 years of age: Dissolve 1 tablet every 2-3 hours. The maximum daily dose is 8 tablets. The duration of the course of treatment is 5-7 days.

Side effect

  • skin rash;
  • hives;
  • angioedema;
  • dizziness;
  • violation of falling asleep;
  • increased excitability;
  • increased blood pressure;
  • tachycardia;
  • dry mouth;
  • nausea, vomiting;
  • epigastric pain;
  • increased intraocular pressure;
  • anemia, thrombocytopenia, agranulocytosis, hemolytic anemia, aplastic anemia, methemoglobinemia, pancytopenia;
  • renal colic;
  • glucosuria;
  • interstitial nephritis;
  • papillary necrosis;
  • bronchial obstruction.

Contraindications

  • severe atherosclerosis of the coronary arteries;
  • arterial hypertension(severe course);
  • diabetes mellitus (severe course);
  • concomitant use of tricyclic antidepressants, MAO inhibitors, beta-blockers;
  • simultaneous administration of drugs containing components of the Rinza drug;
  • pregnancy;
  • lactation period;
  • children up to 15 years old (Rinza Lorsept - up to 6 years old, Lorsept Anesthetics - up to 12 years old);
  • hypersensitivity to the components of the drug.

Application during pregnancy and lactation

The appointment of Rinza's drug during pregnancy and lactation is contraindicated.

Application in children

The drug is contraindicated in children and adolescents under 15 years old (Rinza Lorsept - up to 6 years old, Lorsept Anesthetics - up to 12 years old).

special instructions

During the period of using Rinza's drug, you should refrain from drinking alcohol, sleeping pills and anxiolytic drugs (tranquilizers).

Do not take at the same time with other preparations containing paracetamol.

Influence on the ability to drive vehicles and use mechanisms

During the period of treatment, one should refrain from driving vehicles and engaging in other potentially hazardous activities that require increased concentration of attention and speed of psychomotor reactions.

Drug interactions

Rinza enhances the effects of MAO inhibitors, sedatives, ethanol (alcohol).

With the simultaneous use of Rinza's drug with antidepressants, antiparkinsonian drugs, antipsychotics, phenothiazine derivatives, the risk of urinary retention, dry mouth, and constipation increases.

Glucocorticosteroids (GCS), when used simultaneously with Rinza, increase the risk of developing glaucoma.

Paracetamol reduces the effectiveness of diuretic drugs.

Ethanol (alcohol) enhances the sedative effect of antihistamines.

The use of chlorphenamine simultaneously with MAO inhibitors, furazolidone can lead to hypertensive crisis, agitation, hyperpyrexia.

Tricyclic antidepressants enhance the adrenomimetic effect of phenylephrine, the simultaneous administration of halothane increases the risk of ventricular arrhythmia.

Phenylephrine reduces the hypotensive effect of guanethidine, which, in turn, enhances the alpha-adrenergic activity of phenylephrine.

With the simultaneous use of Rinza with barbiturates, diphenin, carbamazepine, rifampicin and other inducers of liver microsomal enzymes, the risk of developing the hepatotoxic effect of paracetamol increases.

Analogs of the drug Rinza

Structural analogs for active substance and pharmacological effect(anilides in combinations):

  • Adjikold Hotmix;
  • Adjikold;
  • AnGriCaps maxim;
  • Antigrippin;
  • AntiFlu;
  • AntiFlu Kids;
  • Apap S Plus;
  • Brustan;
  • Vicks Active Symptomax;
  • Gevadal;
  • Gripex;
  • Grippostad;
  • Grippostad Good Knight;
  • Grippostad C;
  • GrippoFlu for colds and flu;
  • Grippoflu extra for colds and flu;
  • Gripand;
  • Gripand HotActive;
  • Daleron C;
  • Daleron C junior;
  • Children's Tylenol for colds;
  • Dolaren;
  • Dolospa tabs;
  • Ibuklin;
  • Infloblock;
  • Influnet;
  • Caffetin;
  • Kaffetin Cold;
  • Codeine + Paracetamol;
  • Codelmixst;
  • Coldact Flu Plus;
  • Coldrex;
  • Coldrex MaxFlu;
  • Coldrex Knight;
  • Coldrex Hotrem;
  • Coldrex Junior Hot Drink;
  • Coldfree;
  • Coffeedon;
  • Lemsip;
  • Maxicold;
  • Maxicold Reno;
  • Mexavit;
  • Migraine;
  • Migrenol;
  • Mulsinex;
  • Next;
  • Neoflu 750;
  • Novalgin;
  • Padewix;
  • Panadein;
  • Panadol Extra;
  • Panoxen;
  • Paracodamol;
  • Paracetamol Extra;
  • Paracetamol Extra for children;
  • Pentalgin;
  • Pentaflucin;
  • Pentaflucin daily;
  • Plivalgin;
  • Colds;
  • Passage forte;
  • Rinzasip;
  • Rinzasip with vitamin C;
  • Rinikold;
  • Rinikold HotMix;
  • Saridon;
  • Solpadein;
  • Stopgripan;
  • Stopgripan Forte;
  • Strimol plus;
  • Tylenol for colds;
  • TeraFlu;
  • TeraFlu for flu and colds;
  • TeraFlu for flu and colds Extra;
  • TeraFlu Extra;
  • TeraFlu Extratab;
  • Toff plus;
  • Trigan D;
  • Fastorik;
  • Fastorik plus;
  • Febriset;
  • Femizol;
  • Fervex;
  • Fervex for children;
  • Fervex rhinitis;
  • Flukoldin;
  • Flucoldex;
  • Flucomp;
  • Flustop;
  • Khairumat;
  • Andrews Unswehr;
  • Efferalgan with Vitamin C.

In the absence of analogues of the drug for the active substance, you can follow the links below to the diseases for which the corresponding drug helps, and see the available analogues for the therapeutic effect.

Rinza is a combined drug that has an analgesic, antipyretic, vasoconstrictor, anti-edema, antiallergic and psychostimulating effect. It is used for the symptomatic treatment of acute respiratory diseases.

Release form and composition

Rinza's dosage form - tablets for oral administration (10 pcs. In blisters, 1 blister in a cardboard box).

The active ingredients of the drug (in 1 tab.):

  • Paracetamol - 500 mg;
  • Caffeine - 30 mg
  • Phenylephrine hydrochloride - 10 mg;
  • Chlorphenamine maleate - 2 mg

Additional components: sodium carboxymethyl starch (type A), magnesium stearate, povidone (K-30), colloidal silicon dioxide, sodium methyl parahydroxybenzoate, talc, corn starch, crimson dye (Ponso 4R).

Indications for use

Rinza is used for the symptomatic treatment of colds and acute respiratory viral infections (including influenza), accompanied by rhinorrhea, fever and pain.

Contraindications

The following conditions and diseases are contraindications to the use of Rinza:

  • Severe arterial hypertension;
  • Severe atherosclerosis of the coronary arteries;
  • Severe diabetes mellitus;
  • Simultaneous administration of drugs that contain substances that make up Rinza;
  • The need to use MAO inhibitors, tricyclic antidepressants, beta-blockers;
  • Age up to 15 years;
  • Pregnancy;
  • Lactation;
  • Hypersensitivity to the components of the drug.

Special observation during the treatment period is necessary for patients who have been diagnosed with:

  • Arterial hypertension;
  • Hyperthyroidism;
  • Diabetes;
  • Pheochromocytoma;
  • Chronic obstructive pulmonary disease;
  • Bronchial asthma;
  • Diseases of the blood;
  • Congenital hyperbilirubinemia (Rotor, Dubin-Johnson or Gilbert syndromes);
  • Hepatic / renal impairment;
  • Hyperplasia of the prostate gland;
  • Closed-angle glaucoma;
  • Deficiency of glucose-6-phosphate dehydrogenase.

Method of administration and dosage

Tablets are taken orally 1 pc. 3-4 times a day. The maximum permissible daily dose is 4 tablets.

You can take Rinza for no more than 5 days.

Side effects

Possible side effects of the drug:

  • Cardiovascular system: increased blood pressure, tachycardia;
  • Digestive system: pain in the epigastric region, nausea, vomiting, dry mouth, hepatotoxic effect;
  • Central nervous system: violation of the process of falling asleep, dizziness, increased irritability;
  • Hematopoietic system: anemia (including aplastic and hemolytic), agranulocytosis, thrombocytopenia, pancytopenia, methemoglobinemia;
  • Urinary system: papillary necrosis, glucosuria, renal colic, interstitial nephritis;
  • Respiratory system: bronchial obstruction;
  • Organ of vision: paresis of accommodation, mydriasis, increased intraocular pressure;
  • Allergic reactions: skin rash, urticaria, itching, angioedema.

An overdose of Rinza is mainly due to the intake of a high dose of paracetamol - more than 10-15 g. Symptoms: nausea, vomiting, anorexia, pallor of the skin, an increase in prothrombin time, an increase in the activity of hepatic transaminases, hepatonecrosis. First aid involves gastric lavage and the intake of activated charcoal. Further treatment is symptomatic. After 8-9 hours after the overdose, methionine is administered, after 12 hours - acetylcysteine.

special instructions

During the period of drug treatment, you should not:

Drug interactions

Paracetamol, which is part of Rinza, reduces the effectiveness of diuretics.

With the combined use of the drug with barbiturates, carbamazepine, rifampicin, diphenin and other inducers of microsomal liver enzymes, the likelihood of developing the hepatotoxic effect of paracetamol increases.

Phenylephrine reduces the hypotensive effect of guanethidine, and it, in turn, increases the alpha-adrenergic activity of phenylephrine. The adrenomimetic effect of phenylephrine is enhanced by tricyclic antidepressants.

Chlorphenamine in combination with furazolidone or MAO inhibitors can lead to hyperpyrexia, agitation and hypertensive crisis. Ethanol enhances the sedative effect of chlorphenamine.

With the simultaneous use of Rinza with antipsychotic and antiparkinsonian drugs, antidepressants and phenothiazine derivatives, dry mouth, constipation, and urinary retention may occur.

When the drug is combined with halothane, the risk of developing ventricular arrhythmias increases, with glucocorticosteroids - glaucoma.

Rinza enhances the effects of ethanol, sedatives and MAO inhibitors.

Terms and conditions of storage

Store in a dry, dark place, out of reach of children, at temperatures up to 25 ºС.

Shelf life is 3 years.