Acylact suppositories - instructions for use in gynecology. "Acylact", candles: customer reviews, instructions for use and analogs Is it possible to drink when you take candles acylact

05.07.2020 Insulin

In case of violations of the microflora of the vaginal tract, special local funds... Good candles, according to reviews - Atzilact, they are more often than others prescribed in gynecology.

Description and action of Atzilact

Vaginal suppositories Acylact is a drug with an immunomodulatory effect. The composition contains acidophilic lactobacilli - an analogue of natural representatives of the vaginal microflora. The candles look like a cone, a cylinder, yellow-gray or beige in color, with a specific aroma.

Each candle contains up to 10 million bacteria, which corresponds to one single dose.

Among the auxiliary substances are paraffin, confectionery fat, emulsifier. Candles cost about 175 rubles per pack (10 pieces). You can also find Acylact tablets on sale, the cost is 360 rubles (30 tablets). The action of the drug is due to its composition. Each candle contains live bacteria in the form of a lyophilisate with the inclusion of a protective environment. The milky environment is necessary for the rapid activation of bacteria after entering the vagina.

The agent is an antagonist of pathogenic microorganisms. With a sufficiently high number of acidophilic bacteria on the vaginal mucosa, they inhibit the reproduction of harmful microbes, opportunistic flora. These include E. coli, coccal flora, enterobacteria, etc. This contributes to the normalization of the microcenosis of the genital area in women.

Indications of the drug

The acidic environment of the vagina, which is provided by the introduction of suppositories, is unsuitable for the pathogenic flora. Therefore, the main indication for the use of Acylact suppositories is the need to increase local immunity.

Suppositories are helpful as monotherapy or in combination treatment for:


Medicine in complex therapy should be placed in case of inflammation of the uterus, cervix, and appendages to prevent the development of dysbiosis (this happens when using local and systemic antibiotics).

The indications for use are infectious complications after operations, childbirth, invasive examinations.

The use of the drug is justified after taking antibiotics for the treatment of any common diseases (in addition, rectal suppositories with a probiotic complex can be used).

Instructions for use

The dosage of the drug is 1-2 suppositories / day, they need to be used for 10 days. V preventive purposes it is allowed to put suppositories for 5-7 days. How much the course of admission will be in each individual case should be decided by the attending physician. The treatment rules are as follows:


Pregnant women with a change in the smear towards 3-4 degrees of purity are treated with Acylactom 1 injection before bedtime for 10 days or more. The duration of the course is determined by the results of the smear analysis, which should be equated to 1-2 degrees of purity. Symptoms (discharge, itching, pain) should also completely stop. After taking antibiotics, the course will be 10 days, 2 suppositories / day. 20 days after the therapy for any indication, it can be repeated.

Other data

There are a number of analogs that, with the consent of the doctor, can replace this pharmacological agent.

It is not recommended to have sex during treatment. It is best to start therapy after the end of menstruation, but, if necessary, the course for menstruation is not interrupted. There are no contraindications for use, since bacteria are related to the human body.

The drug goes well with systemic therapy - with antibiotics, antiviral agents, immunomodulators. In case of candidiasis, it is recommended to first use suppositories with antiseptic and antifungal effects, and then restore the microflora with the help of Acylact suppositories. If the medicine has an unpleasant, rancid odor, it is expired or not stored properly. Such suppositories should not be administered.


Acylact vaginal suppositories is a microbial mass of live, antagonistically active acidophilic lactobacilli strains Lactobacillus acidophilus 100ash, NK1, K3Sh24, freeze-dried in a cultivation medium with the addition of a protective sucrose-gelatin-milk medium and formed into medical suppositories.
One suppository contains at least 107 live acidophilic lactobacilli (1 dose), auxiliary substances - solid oil paraffin, emulsifier T - 2, solid fat. Suppository weight - 1.3 g.
Live acidophilic lactobacilli have high antagonistic activity against pathogenic and opportunistic microbes, including staphylococci, enteropathogenic E. coli, Proteus, which determines the normalizing effect of the drug in violations of the bacteriocenosis of the female genitalia. Lactobacilli metabolize the glycogen of the vaginal epithelium to lactic acid, which maintains the vaginal pH at 3.8-4.02. High concentration lactic acid creates unfavorable conditions for the vital activity of acid-sensitive pathogenic and opportunistic bacteria. By acidifying the mucous membrane of the genitals, lactobacilli participate in the formation of an ecological barrier and ensure the resistance of the mucous membrane of the genitals to extraneous microflora.

Indications for use

SuppositoriesAcylact are used to treat diseases of the female genitals, accompanied by a violation normal microflora:
- nonspecific colpitis (as an independent remedy or after the end of the course antibacterial therapy);
- vaginal dysbiosis, incl. bacterial vaginosis (as an independent remedy or in combination therapy);
- subacute and chronic stages inflammatory processes of the female genital area (after the end of the course of antibiotic therapy for the purpose of rehabilitation);
- hormone dependent colpitis, incl. senile (as an independent remedy or against the background of specific hormonal therapy);
- preparation for planned gynecological operations in order to prevent postoperative infectious complications;
- prenatal preparation of pregnant risk groups for the development of inflammatory diseases in order to prevent and treat vaginal dysbiosis;
- as an adjuvant in combination and after specific antimicrobial, antiviral and immunomodulatory therapy in the treatment of urogenital infections and sexually transmitted diseases (gonorrhea, urogenital chlamydia, urogenital herpes, etc.).

Mode of application

SuppositoriesAcylact applied intravaginally.
In the treatment of senile vaginitis of a hormonal nature and vaginal dysbiosis - 1 supp. 2 times a day for 5-10 days.
In case of violation of the purity of the vaginal secretion in pregnant women up to III-IV degree, the drug is used in 1 supp. 1-2 times a day for 5-10 or more days until the purity of the vaginal secretion is restored to the I-II degree and the disappearance of clinical symptoms.
In order to prevent purulent-septic complications, 1 supp is used. 1-2 times a day for 5-10 days before the proposed operation or delivery.
For the purpose of rehabilitation therapy after the use of antibiotics, 1 supp is used. 1-2 times a day for 10 days. The course is repeated according to the doctor's prescription in 10-20 days.

Side effects

Not installed.

Contraindications

:
Suppositories are contraindicated. Acylact with vulvovaginal candidiasis.

Pregnancy

:
Decision on prescribing a drug Acylact women during lactation and pregnancy are treated by a doctor.

Interaction with other medicinal products

Combined use of suppositories is allowed Acylact with antimicrobial, antiviral and immunomodulatory drugs.
The simultaneous use of the drug Acylact with intravaginal forms of antibiotics is not desirable.

Overdose

:
Overdose reports Acylacta have not been reported.

Storage conditions

At a temperature of 2-10 ° C.
Keep out of the reach of children.

Release form

Acylact - vaginal suppositories.
In a contour acheikova packing 5 pcs .; in a pack of cardboard 2 packs or in a contour acheikova package 10 pcs.; in a pack of cardboard 1 packing.

Compound

:
1 suppository Acilact contains: live individuals of acidophilic lactobacilli at least 107.
Suppository base: solid fat; paraffin; emulsifier.

Additionally

:
Before intravaginal administration of the suppository, the packaging material is removed.
Combined use of suppositories is recommended Acylact and one of the oral forms of acylact.
The use of suppositories can be combined with the simultaneous administration of antimicrobial, antiviral and immunomodulatory therapy. However, it is not recommended to combine with the simultaneous local administration of antibacterial drugs.

Main settings

Name: ACILACT CANDLE

Acylact is a domestic probiotic bacterial preparation based on live acidophilic lactobacilli. He is in the highest degree antagonistic to pathogenic and facultative pathogenic bacteria, including staphylococci, enteropathogenic Escherichia coli, Shigella, Proteus. Such in good sense The "hardiness" of acylact predetermines its corrective effect in cases of violations of the bacteriocenosis of the intestine and oral cavity. Thus, the scope of application of the drug is wide enough and covers diseases of the mucous membrane. oral cavity inflammatory genesis and dysbiotic diseases gastrointestinal tract... One of the therapeutic "specializations" of acylact is generalized periodontitis... The drugs of choice in this case are antibacterial agents, but often antibiotic therapy does not justify itself and only aggravates clinical picture... A massive antimicrobial attack seriously and permanently disrupts the biocenosis of the oral cavity, suppressing the local immunity of the mucous membranes. Such population deviations of the bacterial microflora are difficult to correct and entail the emergence of resistant strains of microorganisms, followed by dysbacteriosis and the development of hypersensitivity to various allergens, including those of microbial origin. In recent years, in order to balance the autoflora, increase immunity, and minimize allergic phenomena, periodontists increasingly often resort to probiotics - preparations containing live bacteria, one of which is acylact. This medicine performed well in clinical research in patients with periodontitis. So, already after 2-3 therapeutic sessions, they showed a distinct decrease in the intensity of the inflammatory process, that is, acylact had a pronounced anti-inflammatory effect on the periodontal tissues. As the inflammation in the gums was eliminated, the permeability of the capillary walls decreased. Against the background of acylactom therapy, the content of lysozyme, an enzyme endowed with the ability to cause hydrolysis of bacterial cells, significantly increased in the saliva of patients.

After the end of the drug course, a significant decrease in microbial contamination of periodontal tissues was observed.Bacteria that most often cause periodontitis - Staphylococcus aureus and auricularis, Streptococcus mutans, Candida tropicalis, Enterobacter cloacae - were practically not isolated during sowing. When monitoring the long-term results of pharmacotherapy, it was found that the use of acylact ensures the preservation and maintenance of the normal composition of the microflora of the oral cavity for up to six months, while in the control group of patients receiving other treatment, the quantitative and qualitative composition of unwanted microorganisms returned to their previous levels in 1-3 post-therapeutic months. In addition to the listed positive changes, more than a third of patients taking acylact noted the normalization of the functions of the gastrointestinal tract, namely: the disappearance of abdominal pain, discomfort, "revitalization" of peristalsis. Thus, the results of clinical, microbiological and immunological studies indicate that acylact has antibacterial, anti-inflammatory and immunomodulatory effects and can be effectively used in generalized periodontitis.

Among other diseases that acylact successfully cope with is vaginal candidiasis, which often occurs against the background of antibiotic treatment for bacterial vaginosis. The essence of antibacterial drugs, which does not know sentimentality, is such that, having destroyed all conditionally and unconditionally pathogenic microorganisms, they completely withdraw themselves from the establishment of "constitutional order" in the vagina (read: from the restoration of normal microflora). In such cases, it is recommended to take probiotic drugs, incl. acylacta, which helps to reduce the risk of recurrence of the disease by increasing the protective properties of the vagina.

Pharmacology

The drug has a high antagonistic activity against pathogenic and opportunistic microorganisms, including staphylococci, shigella, enteropathogenic Escherichia coli, Proteus, which determines the corrective effect of the drug in violations of the bacteriocenosis of the oral cavity and intestines.

Release form

20 pcs. - bottles (1) - cardboard packs.
30 pcs. - bottles (1) - cardboard packs.
60 pcs. - polymer cans (1) - cardboard packs.

Dosage

Depending on the disease, the drug is used by mouth, without preliminary dissolution, with a drink boiled water room temperature or dissolving.

The daily dose and duration of the course of treatment is determined by the doctor, depending on clinical form diseases and severity of dysbiosis.

For diseases of the oral cavity:

For diseases of the mucous membrane, the drug is used after meals, dissolving the tablet.

With glossitis, 5 doses are prescribed per day in 2-3 doses, the course of treatment is 14-15 days. With recurrent aphthous stomatitis and ulcerative necrotizing gingivitis, treatment is carried out according to the same scheme in two courses with a break of 7 days.

In case of pathological processes in the oral cavity caused by systemic diseases, 10 doses per day are prescribed in 4 doses in two courses of 14-15 days each with a break of 7 days.

With diseases of the gastrointestinal tract:

The tablet preparation is taken orally no later than 20-30 minutes before meals with water.

Patients with intestinal disorders are prescribed 5 doses 2-3 times a day.

In acute inflammatory bowel processes, the course of treatment is 7-8 days, with protracted and recurrent forms of the disease - 14-21 days.

If necessary, the doctor prescribes repeated courses under laboratory control.

In case of violations of the normal intestinal microflora in children with atopic dermatitis 5 doses per day in courses of 20 - 25 days, with breaks of 1.5 - 2 months. The number of courses is determined by the condition of the skin and the normalization of the intestinal microflora.

Interaction

The use of tablets can be combined with simultaneous antibacterial, antiviral and immunomodulatory therapy.

Side effects

Not identified.

Indications

For diseases of the oral cavity:

  • inflammatory diseases of the oral mucosa (glossitis, aphthous stomatitis, necrotizing ulcerative gingivitis);
  • pathological changes in the oral mucosa accompanying systemic diseases (lichen planus, erythema exudatip multiforme, Sjogren's disease);
  • other diseases of the oral cavity associated with dysbiosis (galvanism, multiple lesions of the teeth with caries, periodontitis), preparation for planned maxillofacial operations in order to prevent pyo-inflammatory complications.

With diseases of the gastrointestinal tract:

  • sharp intestinal infections, foodborne toxicoinfections caused by opportunistic microorganisms or unknown etiology; rotavirus gastroenteritis;
  • long-term intestinal disorders, especially in young children;
  • protracted and chronic colitis and enterocolitis of infectious and non-infectious etiology, accompanied by a violation of microflora;
  • medium and light form ulcerative colitis in adults;
  • weakened, often ill children and adults with symptoms of dysbiosis. including those accompanied by an immunodeficiency state;
  • complex therapy of atonic dermatitis in children with symptoms of intestinal dysbiosis.

Corrective therapy with acylactom can be prescribed after a course of treatment with bacteriophages.

Contraindications

Not installed.

Application features

Application during pregnancy and lactation

Lactobacilli are representatives of the normal human microflora. Therefore, preparations based on them can be used during pregnancy and lactation.

Application in children

The drug is approved for use in children.

special instructions

Influence on the ability to drive vehicles and use mechanisms:

The drug does not affect the performance of activities requiring special attention and quick reactions (management vehicles, machinery, etc.).

Vaginal suppositories Acylact is a multifunctional drug used to treat different forms such a disease as thrush in women. However, when deciding on their use for therapeutic purposes, it should be remembered that the medicine cannot act as the main medicinal anti-candidiasis agent.

Acylact for thrush has a powerful antifungal action... In addition, it has a beneficial effect on the vaginal microflora, restoring it and preventing the re-development of candidiasis. But this medicine is not as harmless as many patients think, therefore, these suppositories should be used with extreme caution for thrush.

Acylact: indications and contraindications

Vaginal suppositories Acylact can be used not only for thrush or after it, but also for the treatment of other gynecological pathologies in women. In particular, it is used when:

  • non-infectious colpitis;
  • gardnerellosis;
  • colpitis of hormonal etiology;
  • preparation for an operation in the area of ​​the pelvic organs;
  • chlamydia;
  • gonorrhea;
  • genital herpes;
  • trichomoniasis;
  • inflammation of the cervix.

The only contraindication to the use of Acilact suppositories in women is vaginal thrush. That is, it is forbidden to use it as a separate tool - it simply will not have any effect.

Suppositories can only be put in parallel with the use antifungal drugs and also after complete cure thrush.

Method of using Acylact suppositories for the treatment of candidiasis

Acylact for thrush in women should be used in the morning and evening. Before the introduction of suppositories by the intravaginal method, it is necessary to put a daily pad on the underwear. The fact is that after dissolving the suppository, a certain amount of the drug may leak out. In order not to stain your laundry, you should resort to the use of personal hygiene products.

Acylact suppositories, used for thrush, should be administered only after preliminary washing. Then you should wait until the skin of the genitals is dry, and only then proceed to the procedure.

In order for Acylact in the form of suppositories for thrush to give the maximum result, it must be used in parallel with tablets or lyophilisate. With the help of complex therapy with this drug, you can quickly restore the vaginal microflora without risking the patient's health.

Vaginal suppositories Acylact in the treatment of thrush cannot be used together with antibacterial drugs since these medicinal substances do not interact with each other. Due to their incompatibility, allergic reactions and vaginal dysbiosis, so do not risk your own health!

The use of Acylacta after suffering thrush in women

Acylact after thrush is used as prophylactic... This drug is a powerful probiotic that can be safely used not only for women, but also for preventive therapy in young girls.

In parallel with the introduction of Acylact suppositories, the patient is prescribed a light diet that excludes all junk food - fatty, fried, spicy, smoked foods and sweets. This will help to finally get rid of the symptoms of thrush, as well as significantly strengthen the local immunity.

Acylact for the treatment of candidiasis during pregnancy

Acylact during or after thrush is allowed to be used to treat expectant mothers. This drug contains exclusively lactobacilli, so it can be considered absolutely harmless to the fetus. The Acilact medicine can be compared with the daily consumption of fermented milk products.

Suppositories should be placed during pregnancy not only in case of development of thrush, but also in case of vaginal dysbiosis. After the end of the course of therapy, the patient will need to be re-examined by a doctor, as well as a vaginal smear to confirm that the pathology has been completely cured.

Side effects and drug analogues

The only one side effect after using the drug, there is an allergy to the components that make up it. It is expressed with itching, burning, hyperemia of the mucous membranes and skin of the genitals. The patient may experience discomfort when walking, and the secretion of vaginal mucus may increase slightly.

As a rule, to relieve these symptoms, it is enough to take an antihistamine pill, as well as wash with a decoction. medicinal plants that have a calming and anti-allergic effect (chamomile, calendula, eucalyptus).

If this drug for any reason is not suitable for the patient, it is replaced by another drug with a similar principle of action. These include:

  1. Suppositories Lactobacterin.
  2. Lactonorm - vaginal capsules.
  3. Ecofemin in the form of vaginal capsules.
  4. Betadine vaginal suppositories.
  5. Hexicon candles.

Only the gynecologist can make the decision to replace the drug. Especially when it comes to a pregnant woman, since during this period of time, any experiments with health can have unpredictable consequences.

A complex drug, the purpose of which is to restore the natural microflora in the intestinal loops - injections, tablets and suppositories "Atsilakt". The instructions for use indicate that a quick positive result is achieved due to the optimal content of acidophilic lactic acid bacteria. The tool has proven itself in gynecology, gastroenterology and other areas of medicine, as an effective component of pharmacotherapy for various pathologies, as well as an effective prophylactic drug.

What is the form of release

In the pharmacy network, the drug "Atsilakt" is presented as a lyophilisate, packaged in vials of 3 doses or 5 doses. Immediately before the introduction into the human body, the agent is diluted with pharmacy water. Pharmacy packaging contains 5 pcs. Or 10 pcs.

There is also the form of tablets, which contain at least 10 * 7 live acidophilic bacteria. However, the best of all is the form rectal suppositories- due to the ease of use. Packing in specially designed protective blisters, 10 pcs.

Compound

Based on the attached instructions, it follows that the active substance of the drug "Acylact" are live acidophilic lactobacilli - three subspecies. To ensure survival, they are dried in combination with the medium on which they were grown.

There are no additional components in the form of a lyophilisate and tablets. Whereas in suppositories for the base, solid fat, paraffin, and also an emulsifier are added. Their task is to shape suppositories, distribute lactobacilli evenly, and maintain their medicinal properties.

Pharmacological effects

It is the presence in the composition of the medication "Atsilakt", the instructions for use give such information, several strains of live acidophilic lactobacilli causes a lot pharmacological effects medication:

  • antimicrobial - suppression of the growth of pathogenic microorganisms, including staphylococci, Escherichia coli;
  • antagonistic - lactobacilli resist pathogenic flora for nutrients;
  • preventive - due to an increase in local immunity in the intestine, the formation of various diseases arising against the background of immunodeficiency;
  • due to suppositories with lactobacilli, physiologically "acidic" pH is maintained - in the range of 3.8-4.2;
  • improvement of general well-being.

Everything pharmacological properties cause a variety of indications for the use of the medication.

Tablets, injections, suppositories "Atzilakt": what helps the medicine

Specialist preparation for restoration of natural microflora of cavities human body"Acylact" is used in the following cases:

  • preoperative preparation - on the structures of the oral cavity, head;
  • dysbiosis in the area of ​​the digestive structures;
  • non-infectious etiology of colpitis;
  • a disorder in the composition of natural microorganisms, formed as a result of severe systemic pathologies;
  • preparation for gynecological surgery;
  • exacerbation chronic pathologies obstetric organs in gynecology;
  • prevention of purulent complications after maxillofacial surgery;
  • preparatory stage for delivery of women;
  • diagnosed bacterial vaginosis;
  • prolonged course of colpitis, as well as enterocolitis;
  • dysbiosis of the structures of the urogenital tract;
  • colpitis of hormonal etiology;
  • recovery stage after a course of antibiotic therapy;
  • long-term intestinal disorders in babies;
  • atopic form of dermatitis;
  • complex therapy of sexually transmitted pathologies;
  • dysbiosis against the background of immunodeficiency;
  • aphthous stomatitis;
  • periodontitis;
  • rotavirus gastroenteritis.

Only a specialist should make an informed decision about the need to take lactobacilli.

The drug "Atsilakt": instructions for use

Each of the forms of the drug has its own nuances for the correct introduction into the human body, therefore, preliminary acquaintance with the attached instructions from the manufacturer is a prerequisite for the success of pharmacotherapy.

So, the lyophilisate "Atsilakt" must be dissolved immediately before use - either in bottled water, or in plain boiled drinking water. The proportions of dissolution will be calculated based on the number of doses of the active substance prescribed on the vial with the medication. For each dose of dry matter, ml of purified water is required to dissolve.

After determining the required volume of water, it is poured into a mug. A small amount of water is added to a bottle with a dry concentrate, everything is thoroughly shaken up. As a result, a homogeneous suspension should be formed - beige or gray. The suspension then needs to be added to the water prepared in a mug. The ready-made solution is used at the rate of 1 tsp. suspension is 1 dose of the drug.

The frequency of taking the drug, as well as the total duration of the treatment course, will be determined by a specialist based on the diagnosed pathology:

  • with stomatitis or gingivitis - rinsing the mouth every morning, evening;
  • with holossitis - 5 doses of 2-3 r / s, at least 10-14 days;
  • with aphthous stomatitis - 5 doses of 2-3 r / s;
  • with exudative erythema - 10 doses per day, divided into 4 doses;
  • for intestinal disorders in babies - 5 doses in 2 doses, while adults need 5 doses of 2 - 3 r / s;
  • in babies with atopic dermatitis and dysbiosis, treatment consists of taking 5 doses of the drug per day, at least 20 - 25 days;
  • on defeat inflammatory processes the female reproductive system, a lyophilisate to be taken in 5 doses is prescribed every morning, evening by irrigating the vagina.

The form of tablets "Acylact" involves the use of 1 dose twice, or even three times a day. In infants with acute disorders - 2-3 doses per dose. Whereas for adults the number of doses is recommended for 5 pcs. With an acute process, the total duration is 7-8 days, with chronic course pathology - 2.5-4 weeks.

Suppositories "Atzilakt" are used in gynecology. They can be administered both rectally and intravaginally - in direct proportion to the age and gender of the patient. Optimal doses:

  • for pathologies of urogenital structures - 1 pc. 2 r / s;
  • in case of violations of the composition of the vaginal discharge - 1 pc. 1-2 r / s;
  • prevention of purulent complications after surgery or childbirth - 1 pc. 2 r / s;
  • restoration of the concentration of its own beneficial microflora, for example, after the forced intake of antibacterial agents - 1 pc. rectally 2 r / s.

The optimal timing of suppository therapy is determined by a specialist on an individual basis. If necessary, courses can be repeated 2-3 times.

Unwanted effects

Since each of the above forms of the drug contains exclusively dried acidophilic lactobacilli, the appearance of undesirable reactions against the background of a therapeutic or prophylactic course of therapy with a drug is an extremely rare occurrence.

In a number of cases, individual intolerance to the components of the drug was recorded in the form of mild allergic disorders - urticaria, moderate itching or burning.

No dyspeptic disorders, no difficulties with emptying the intestines while taking dox of lactobacilli were not observed. The specialist should be notified of each case of deterioration of health due to the drug - in order to correct the treatment.

Analogues of the drug "Atsilakt"

Complete analogs in composition:

  1. Ecofemin.
  2. Vagilak.
  3. Lactobacterin.
  4. Lactonorm.

Vacation price and conditions

Average price "Atsilakt", candles 10 pcs. (Moscow) is 110 rubles. You can buy a medicine in Minsk for 4 - 5 bel. rubles. Price in Kiev - 200 hryvnia, in Kazakhstan - 656 tenge. Available without a prescription.

General reviews

In general, the impression of acidophilic lactobacilli, presented in concentrated form in the drug "Acylact", is positive. The doctors' comments say that thanks to the timely started therapy, it is possible to adjust the required pH of the vagina in women or in the intestinal lumen in children and adults in a short time.

At the same time, the list of restrictions on taking the medication is much shorter than a similar list of contraindications for other drugs. In addition, there are practically no undesirable effects when taking the drug. Therefore, it is widely used by specialists in pediatric practice.