Combined drugIt has an analgesic, antipyretic, controversial action.
Paracetamol - Analgesic Antipyatik. Blocks CHA mainly in the CNS, affecting the centers of pain and thermoregulation; It has analgesic and antipyretic effect.
Sodium metamizol is an antipictic analgesic derivative of pyrazolone. It has a pronounced analgesic effect.
Caffeine - psychostimulator, improves the well-being of patients and reduces headache Vascular genesis (including migraine).
Phenobarbital - Barbiturate, increases the analgesic efficacy of sodium and paracetamol metamizole.
Codeine has an anesthetic effect due to the excitation of opioid receptors in various parts of the central nervous system, leading to the stimulation of the antinocyptive system and the change in the emotional perception of pain.
Tablets from white to white with a yellow or cream tint of color, double-screwed, in the form of a capsule with flat side surfaces, with a risk on one side and engraving "Pentalgin" - to another.
Auxiliary substances: Potato starch, povidone (polyvinylpyrrolidone low molecular weight medical), stearin acid, calcium stearate.
6 pcs. - Packaging cell contour (1) - packs cardboard.
6 pcs. - Packaging cell contour (2) - packs cardboard.
10 pieces. - Packaging cell contour (1) - packs cardboard.
10 pieces. - Packaging cell contour (2) - packs cardboard.
12 pcs. - Packaging cell contour (1) - packs cardboard.
12 pcs. - Packaging cell contour (2) - packs cardboard.
10 pieces. - Packaging cell contour (500) - cardboard boxes.
12 pcs. - Packaging cell contour (500) - cardboard boxes.
6 pcs. - Packaging cell contour (500) - cardboard boxes.
Assign 1 tab. 1-3 times / day. Maximum daily dose - 4 tab.
The drug should not take more than 5 days as an anesthetic agent and more than 3 days as an antipyretic remedy without appointing and observing the doctor.
Symptoms: nausea, vomiting, gastralgy, tachycardia, arrhythmia, oppression of the respiratory center.
Treatment: washing the stomach, the purpose of intestinal adsorbents, if necessary, the conduct of symptomatic therapy.
With the simultaneous use of funds that have an inoperative effect on the central nervous system (including sedatives and tranquilizers) is likely to enhance the sedimentation of the sedative effect and the oppressive effect on the respiratory center. Enhances the effect of ethanol on a psychomotor reaction. Sodium metamizole reduces cyclosporine concentration.
Sodium metamizole, displacing oral hypoglycemic drugs due to protein, indirect anticoagulants, GKS and Indomethacin, increases their activity. Tricyclic antidepressants, contraceptive means for intake, allopurinol disturb the metamizole metamizole metabolism in the liver and increase its toxicity.
The simultaneous use of Pentalgin® -Iticn preparation with other non-constidium analgesics can lead to amplification of toxic effects.
Barbiturates, Phenylbutazone and other inductors of microsomal liver enzymes weaken the action of sodium metamizol.
From the CNS: dizziness, drowsiness.
From side of cardio-vascular system: heartbeat, tachycardia.
From side digestive system: Nausea, vomiting, constipation.
From the side of the blood formation system: leukopenia, granulocyptopenia, agranulocytosis.
Allergic reactions: rash, itching, urticaria.
Others: With a long-term uncontrolled reception in high doses - addictive (weakening an anesthetic effect), drug addiction (codeine), hepatic and / or renal failure.
Caution should be used the drug when peptic disease Stomach I. duodenal gut in the remission phase arterial hypertension, in elderly patients.
Caution should be used the drug in elderly patients.
With long-term (more than 1 week) treatment requires control of the picture of peripheral blood and functional state Liver.
When taking the drug Pentalgin ® -ICN, it is possible to change the results of doping control analyzes in athletes.
Reception of Pentalgin ® -icn makes it difficult to establish a diagnosis with acute abdominal pain syndrome.
In patients suffering from atopic bronchial asthma, Polinoses, there is an increased risk of developing hypersensitivity reactions.
Impact on the ability to driving vehicles and control mechanisms
When applying the drug, patients should refrain from potentially dangerous species Activities requiring increased attention and the speed of psychomotor reactions.
Pentalgin-ICN is a complex drug that has an antipyretic, as well as analgesic and contrasting effect. A preparation is produced in tablet and in capsules.
Tablets have white with cream or yellow color, as well as a bico form. Capsules have a flat side texture, on one side there is risk, to another - engraving Pentalgin.
In total, the package is one or two contour cells, in one of them there are six, ten, twelve pieces. The active ingredients in the composition of one tablet are:
Additional substances are considered:
Sample Pentalgin-ICN recipe on Latin:
Rp: Tab. Pentalginum.
D.T.D: N 10 in TAB.
S: 1 tablet 2-3 times a day.
The Pentalgin drug refers to the number of complex medicines that have an antipyretic, as well as an anesthetic and controversial impact, due to the properties of active substances:
Pentalgin is prescribed with the following states:
According to the instructions for use to Pentalgin-ICN, it is known that the drug has certain prohibitions, for example:
According to the instructions, Pentalgin-ICN is used orally on one tablet from one to three times a day, the maximum - to four pieces of tablets per day.
Without observing the Doctor, the drug as an antipyretic and analgesic means should not be used for longer than five days.
According to the instructions for applying to Pentalgin, it is known that negative phenomena may occur when incorrectly or uncontrolled dosage:
Treatment is aimed at reducing the absorption of active ingredients, an integrated therapy is carried out if necessary.
When treating this drug, athletes may vary the results of doping research. When performing long therapy (from 7 days) it is important to control the functioning of the liver and the picture of peripheral blood. With sharp pain sensations The use of Pentalgin-ICN may impede diagnosis.
The probability of occurrence of increased sensitivity is higher in people with pollinozles and atopic bronchial asthma. During the use of a drug patient from driving and work, which requires speed of reactions and increased attention, it is necessary to refrain.
According to the instructions, Pentalgin during the "interesting situation" and breastfeeding is not appointed. Use medicine at the age of twelve years is prohibited.
Pentalgin preparation has an overwhelming effect on the central nervous system An increase in the severity of the oppressive effect on the respiratory center and the soothing effect may occur.
Neopoidal painkillers increase toxic action. Ethanol Impact on the psychomotor reaction increases.
Generic "Pentalgin-ICN" is considered:
It is necessary to keep the drug in a place that is protected from light and moisture, at a temperature of up to twenty-five degrees. Place the medicine imposed away from children. Shelf life - thirty-six months. Recommended by the doctor's prescription.
/ Pentalgin-ICN
Manufacturer
Farmstandart-Lexed, Russia
Pharmacological group
Analgesic
metamizole sodium, codeine, phenobarbital, caffeine, paracetamol
"Pentalgin-ICN" is effective drug, which has a strong analgesic and antipyretic effect, relieves painful syndrome of various etiology. Pentalgin-ICN is particularly effective in severe pains, including migraine. Can be applied walled diseases. The pharmacies are discharged from pharmacies, it is accepted only according to the testimony, it is necessary to refer to your doctor.
White or white pentalgin-ICN tablets with a yellowish or creamy color shade, double-screwed capsule with flat side surfaces, with risks on one side and engraving Pentalgin to another. The composition of one tablet includes:
Pentalgin-ICN is a combined drug, has an analgesic, contamination and antipyretic effect.
Pentalgin-ICN is shown to use with a weak and moderately pronounced pain syndrome of various genesis, including with pains in joints, muscles, radiculitis, menstrual pains, neuralgias, dental and headaches (including migraine). It can be used in coldic diseases accompanied by feverish syndrome.
Pentalgin-ICN has the following contraindications:
With caution take with arterial hypertension easy and middle severity, in old age. Consultation is needed.
Application in pregnancy and breastfeeding: drug is contraindicated during pregnancy and during lactation. Penetrates breast milk.
Pentalgin-ICN is taken inside 1 tablet 1-3 times a day. Maximum daily dose - 4 tablets. Pentalgin-ICN is not recommended to apply more than five days as an anesthetic and more than three days as antipyretic without appointing and observing the doctor.
When using Pentalgin-ICN possible side effects:
Symptoms of overdose:
Treatment in overdose: induction of vomiting, washing the stomach through the probe, the appointment of adsorbents (activated carbon), symptomatic therapy aimed at maintaining vital functions.
The simultaneous use of Pentalgin-ICN with other non-constidium analgesics can lead to amplification of toxic effects. Sedatives and tranquilizers enhance the analgesic effect of the drug. The simultaneous use of metamizole with cyclosporin reduces the level of the latter in the blood. Barbiturates, phenylbutazone and other inductors of microsomal liver enzymes weaken the action of sodium metamizol. Tricyclic antidepressants, contraceptive agents for intake, allopurinol increase the toxicity of sodium metamizol included in the preparation.
During treatment with the drug should be abandoned by alcohol consumption. With long-term reception (more than 5 days), it is necessary to control the pattern of peripheral blood and liver function indicators. Against the background of the use of the drug, it is possible to change the results of doping control of athletes.
In some cases, it is possible to reduce the concentration of attention and the velocity of psychomotor reactions, so during the period of treatment it is necessary to abide by the driving of vehicles and the occupation of other potentially hazardous activities that require increased concentration and speed of psychomotor reactions. Reception of the drug may make it difficult to establish a diagnosis in acute abdominal pain syndrome.
Pentalgin-ICN is released from pharmacies strictly by recipe. Blank 148-1 / y-88. There is a vacation rate by 1 recipe, taking into account the indivisible packaging of 20 tablets.
The drug must be stored in a dry and inaccessible place for children, at a temperature not higher than 25 C. Do not use the drug after the expiration date indicated on the package.
Caffeine.
Additional components: Povidone, starch potato, calcium stearate and stearic acid.
The Pentalgin ICN is produced in the form of tablets packed in packs of 12 pieces.
The medicine is manifested Analgesic, antipyretic and anti-inflammatory act.
For this combination drug is typical anesthetic, antipyretic and anti-inflammatory action that is caused Metamizol and Naproxen .
Thanks to caffeine, the overall health of patients is improved, reduced. able to increase the effect of treatment Sodium metamizol and Paracetamol . Codeine show anti-tech action, by suppressing excitability in a cough center. Anesthetics the effect of this drug is determined by a significant excitation of opiate receptors in the peripheral tissues and the nervous system, which stimulates the antinoceceptive system and the change in emotional pain perception.
As a rule, Pentalgin ICN is prescribed at:
Tablets are not prescribed at:
Reception of tablets can lead to development, swelling of heartbeat, nausea and vomiting, bleeding disorders in the form leukopenia, granulocyptopenia or .
According to the ICN Pentalgin instructions, you can take 1 tablet no more than 3 times a day. At the same time, the daily dosage should not be more than 4 tablets.
It should be noted that this drug can be taken for anesthesia no more than 5 days, and to reduce the heat - up to 3 days. Continuing treatment more than this term is possible only after the prescription of the doctor.
Long-term reception of tablets in elevated doses can lead to a violation of the liver and kidney work, , Reducing the velocity of psychomotor reactions. In addition, the continuous uncontrolled reception of medication in high dosages is addictive, and the presence in its composition Codeine is a drug dependence.
Usually an overdose manifests nausea, vomiting, gastralgia, arrhythmia, inhibition of the respiratory center.
Therapy includes washing the stomach, reception of intestinal adsorbents and other symptomatic treatment.
The combination of Pentalgin-ICN with preparations that affect the nervous system can increase the oppression of the work and sedimentation of the sedative effect on the respiratory center and other systems and organs. Sodium metamizole reduces concentration , displaces oral hypoglycemic drugs from the protein , indirect anticoagulants, significantly increasing their activity. , tricyclic antidepressants, some contraceptive capable of disrupting sodium metamizole in the liver and increase its toxicity.
Simultaneous reception with other nonopioids often enhances toxic effects.
Weaken the action of metamizol sodium can barbiturates, phenylbutazon and various inductors of microsomal liver.
If tablets are accepted for a long time, that is, more than 7 days, patients require control of the state of peripheral and liver activity.
Pentalgin-ICN reception may affect the results various analyzes Doping control in people engaged in sports.
It has been established that this medicine can make it difficult to accurately make a diagnosis in acute abdominal pain syndromes.
Treatment by this drug with atopic different forms Polinosis can lead to the development of hypersensitivity reactions.
Without recipe.
Tablets are stored in a dry, cool and dark place, protected from children.
Such an action is characteristic of: , and Analgin.
The combination with alcohol often enhances the severity of side effects, as well as the effect on psychomotor reactions.
Instructions for medical application drug
Inhibits cyclooxygenase and inhibits the biosynthesis of PG (analgin and paracetamol), stimulates opiate receptors, activates the antinocyptive system (codeine). Inhibits (sedative effect) CNS (phenobarbital). Caffeine increases the permeability of histohematic membranes and increases the concentration of other components in the CNS.
Pain syndrome of various genesis of weak and medium intensity (including arthralgia, myalgia, radiculitis, algodismenae, neuralgia, headache, toothache);
Walled diseases and conditions accompanied by feverish syndrome.
pills; Packaging Contour cell 10 pack cardboard 1;
Pills; Packaging Contour cell 10 pack cardboard 2;
Pills; Packaging Contour cell 12 pack cardboard 1;
Pills; Packaging Contour cell 12 pack cardboard 2;
Pills; Packaging Contour cell 6 pack cardboard 1;
Pills; Packaging Contour cells 6 pack cardboard 2;
Pills; Packaging Contour cell 10 Cardboard box 500;
Pills; Packaging Contour Cellular 12 Cardboard Box 500;
Pills; Packaging Contour cells 6 Cardboard box 500;
The combined drug, has an analgesic, antipyretic, controversial action.
Paracetamol - Analgesic Antipyatik. Blocks CHA mainly in the CNS, affecting the centers of pain and thermoregulation; It has analgesic and antipyretic effect.
Sodium metamizol is an antipictic analgesic derivative of pyrazolone. It has a pronounced analgesic effect.
Caffeine is a psychostimulator, improves the well-being of patients and reduces the headache of vascular genesis (including migraine).
Phenobarbital - Barbiturate, increases the analgesic efficacy of sodium and paracetamol metamizole.
Codeine has an anesthetic effect due to the excitation of opioid receptors in various parts of the central nervous system, leading to the stimulation of the antinocyptive system and the change in the emotional perception of pain.
The pharmacokinetics data of Pentalgin-ICN preparation is not provided.
Application is contraindicated during pregnancy and during lactation (breastfeeding).
Severe liver failure;
- renal failure of severe;
- bronchial asthma;
- anemia, leukopenia;
- states accompanied by oppression of breathing;
- Card-brain hypertension;
- acute myocardial infarction;
- arrhythmias;
- glaucoma;
- alcoholic intoxication;
- deficiency of glucose-6-phosphate dehydrogenase;
- Pregnancy;
- lactation period (breastfeeding);
- children's age up to 12 years;
- Increased sensitivity to the components of the drug.
With caution, the drug should be used for ulcer and duodenal ulcer in the remission phase, with arterial hypertension, in elderly patients.
From the CNS: dizziness, drowsiness.
From the side of the cardiovascular system: heartbeat, tachycardia.
From the digestive system: nausea, vomiting, constipation.
From the side of the blood formation system: leukopenia, granulocyptopenia, agranulocytosis.
Allergic reactions: rash, itching, urticaria.
Others: With a long-term uncontrolled reception in high doses - addictive (weakening of an anesthetic effect), drug dependence (codeine), hepatic and / or renal failure.
Symptoms: nausea, vomiting, gastralgy, tachycardia, arrhythmia, oppression of the respiratory center.
Treatment: washing the stomach, the purpose of intestinal adsorbents, if necessary, the conduct of symptomatic therapy.
Enhances the oppressive effect of ethanol on the CNS.
For long use It is necessary to control the composition of peripheral blood. Avoid simultaneous alcohol intake.
With long-term (more than 1 week) treatment, the picture of the peripheral blood and the functional state of the liver is needed.
When taking the preparation of Pentalgin-ICN, it is possible to change the results of doping control analyzes in athletes.
Treatment of Pentalgin®-ICN makes it difficult to establish a diagnosis with acute abdominal pain syndrome.
In patients suffering from atopic bronchial asthma, half ancient, there is an increased risk of developing hypersensitivity reactions.
Impact on the ability to driving vehicles and control mechanisms
When using the drug, patients should refrain from potentially hazardous activities that require increased attention, and the speed of psychomotor reactions.
List B.: In the dry, protected from light place.
** Drug reference is intended exclusively for informational purposes. For more more full information We ask you to refer to the annotation of the manufacturer. Do not self-medicate; Before starting the use of Pentalgin-ICN drug, you should consult a doctor. EUROLAB is not responsible for the consequences caused by the use of information posted on the portal. Any information on the site does not replace the doctor's advice and cannot serve as a guarantee of the positive effect of the drug.
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** Attention! The information presented in this reference book is intended for medical professionals and should not be the basis for self-treatment. The description of the Pentalgin-ICN preparation is given to be familiarized and is not intended to appoint treatment without the participation of the doctor. Patients need a specialist consultation!
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