After embryo transfer hcg 8. Norm of hcg hormone by day after eco transfer. The dynamics of changes in hormone levels after IVF by day

13.07.2021 Treatment

The effectiveness of the in vitro fertilization procedure can only be judged 2 weeks after the embryo transfer. To determine this, doctors conduct an analysis for hCG after IVF. Deciphering the results of this study allows you to see if pregnancy has occurred, track the condition of the fetus, the dynamics of its development, and helps prevent pathology.

Importance of hCG control in artificial insemination

secretion of human chorionic gonadotropin female body increases after the embryo is fixed in the uterine wall. The hormone is produced by the fetal membrane, called the chorion. Already by the 12th week, it transforms into the placenta, which maintains the viability of the unborn baby until the end of the gestation period. HCG is also injected into the body of a woman who wants to become pregnant to stimulate ovulation. This method is used for both artificial and natural insemination.

An active growth of hCG after implantation is observed by the second week, so the analysis should be taken no earlier than 14 days after conception. The level of the hormone is controlled throughout all 9 months of bearing a child, with IVF this control is especially important. This study allows you to determine the type of pregnancy: uterine or ectopic, multiple or not. In addition, IVF pregnancy is characterized by a very high probability of miscarriage, and monitoring the level of gonadotropin can prevent it.

Methods for determining the concentration of the hormone

Conducting an analysis for gonadotropin with a successful IVF is no different from a study with an ordinary conception. The difference lies in the fact that with natural fertilization, the analysis will be positive already on the 6-9th day after this, although it is usually carried out only after a delay in menstruation. With artificial insemination, the level of gonadotropin becomes indicative only two weeks after cryotransfer or insemination.

The simplest analysis option is to conduct a pregnancy test, which can be done at home. This method is convenient, but not always reliable and often shows a false negative result. Yes, and such tests check only the presence of the hormone in the urine, and not the amount.

A more accurate method is to find out the level of chorionic hormone in the bloodstream. For the study, venous blood is taken from the patient.

It must be taken in the morning on an empty stomach. The result of such a study will determine not only the presence of gonadotropin, but also its level, which, with artificial conception, is of particular importance for maintaining pregnancy.

HCG growth dynamics during in vitro fertilization

The index of chorionic hormone in non-pregnant women is up to 5-7 IU / l (mIU / ml). It increases approximately 5 days after cryotransfer, however, the dynamics of hormone release is rather slow. Its concentration increases significantly after a week and a half. To get the most reliable result, doctors recommend repeating tests at intervals of 2-3 days.

The concentration of gonadotropin can be determined:

  • did attachment occur? gestational sac;
  • number of embryos (one or more);
  • frozen pregnancy;
  • fetal pathology.

The table of hCG values ​​after the transfer of three-day and five-day embryos by day will help to assess the success of IVF and the course of pregnancy.

HCG table and its level by day after embryo transfer

Embryo age
(number of days after puncture)
DPP of a three-day embryoDPP of a five-day-old fetusLeast
gonadotropin index
MeanThe highest rate
7 4 2 2 4 10
8 5 3 3 8 18
9 6 4 3 9 18
10 7 5 8 18 26
11 8 6 11 28 45
12 9 7 17 45 65
13 10 8 22 73 105
14 11 9 30 105 770
15 12 10 39 160 270
16 13 11 68 260 400
17 14
12 120 410 580
18 15 13 220 650 840

The level of hCG at 10-14 DPP begins to increase rapidly. For example, the minimum value of hCG at 13 DPP is already 22, the maximum is 105. By day 36 highest value already reaches 78,000, by 42 - more than 120 thousand.

Gonadotropin in multiple pregnancy

To increase the chances of a successful IVF, several embryos are planted, so often a woman after artificial insemination has twins. Doctors may also suggest preserving and freezing unused embryos in case the attempt fails. With a cryoprotocol, a second IVF cycle can be completed faster.

Table The level of hCG in multiple IVF pregnancy by week

Embryonic weekGonadotropin level
1-2 50-600
2-3 3000–10000
3-4 20000–60000
4-5 40000–2000000
5-6 100000–400000
6-7 100000–400000
7-8 40000–400000
8-10 40000–200000

Starting from the 10th week, the indicator reaches 400,000 and increases rapidly, then growth slows down. If a sharp jump is detected, both in the direction of decrease and increase, the doctor prescribes additional studies to exclude the risks of fetal developmental pathologies.

Reasons for a decrease in the hormone during IVF

First of all, a decrease in hCG indicates that fertilization has not occurred. It also occurs with an ectopic pregnancy or implantation bleeding. A low level of the hormone can serve as a sign that the development of the child has stopped, or that intrauterine death has occurred. A similar situation is also observed with a possible threat of miscarriage. Its first signs are a decrease in chorionic hormone by 50% of the norm and an increase in body temperature. Symptoms include pain in lumbar, the presence of bloody discharge as during menstruation.

In addition, a small indicator of gonadotropin can be observed during normal, but late pregnancy. This is not a cause for concern, since in this case the development of the embryo is normal. In any case, with an underestimated indicator, the patient is sent for re-analysis to check whether the result is erroneous. Sometimes the doctor will additional diagnostics- Ultrasound.

Reasons for the increase in hCG after implantation

It is worth noting that excess secretion of gonadotropin is not uncommon. This is usually explained by the fact that during IVF, several embryos are planted, and two take root. If multiple pregnancy is not confirmed, then the reason increase hCG looking for already in women's health. A high level of the hormone can be observed with gestosis. It will also grow while taking synthetic gestagens. If gonadotropin is exceeded many times in the second trimester of pregnancy, this indicates possible pathologies in the development of the fetus. Sometimes the reason for the growth is the intake of drugs containing gonadotropin in their composition in the early stages.

Checking the level of the hormone "chorionic gonadotropin" is one of the most reliable ways to determine pregnancy. Since hCG is produced in the female body only after a fetal egg has been implanted or an embryo is planted in the uterine wall, as in IVF, it is usually called the pregnancy hormone.

It is this effect that allows you to create rapid tests for home use, which can be bought at any pharmacy. The hCG analysis also shows two strips, like the standard test, but thanks to a special table of hormone levels in urine or blood by day, it is much more convenient to use it.

That's how much surrogate mothers earn -

What is HCG?

Chorionic gonadotropin is produced especially actively in the first days after conception, when its amount doubles every second day. Changes in hCG levels are directly related to the timing of pregnancy. If it came after in vitro fertilization and the age of the fetus is precisely known, then you can check the amount of the hormone in the blood yourself. To do this, you need to do an appropriate analysis in the laboratory.

Best time to check

According to the protocol, hCG during IVF is checked on the 13-15th day after the implantation of the embryo, however, in fact, it is possible to take tests earlier.

Important! According to recent studies, a small amount of this hormone is often found in the blood of non-pregnant women over 40 years of age. That is why the results of hypersensitive tests are not always objective.

It is best to check hCG one week after IVF. It is from the seventh day that tables begin that compare the period after the transfer of the embryo with the level of the hormone. Accordingly, the test on the seventh day will give the most objective picture.

A negative result is not a cause for despair. Firstly, only a doctor can correctly analyze the data obtained, and secondly, the change in hCG must be monitored in dynamics, that is, conclusions can only be drawn after several tests.

And all because sometimes the level of the hormone remains below the average value of the norm even during pregnancy, and it increases only after the embryo begins to develop.

That is why, with a negative test result made on the seventh day, it is recommended to repeat the procedure after 1-2 days.

If hCG rises, we can talk about the onset of pregnancy.

The dynamics of changes in hormone levels and the age of embryos

The IVF procedure consists in transferring an embryo fertilized in vitro, that is, in a test tube, into the uterine cavity. The age of the fetus is counted from the moment of conception. It is determined depending on the technology used.

The results of recent studies have shown that there is a higher chance of getting pregnant with the transfer of five-day-old embryos. That is why most clinics prefer to use whiter developed embryos, and not three-day-old ones, since in such early age it is difficult to assess the viability of the fetus. The age of the embryo is taken into account when assessing the level of hCG.

Sometimes hCG after IVF will first melt and then fall. There are no signs of pregnancy, and after a short delay, most often a week, the patient begins menstruation - more abundant and painful than usual. This indicates the onset of the so-called biochemical pregnancy.

The production of human chorionic gonadotropin begins at the moment when the fetal egg is attached to the wall of the uterus. Its level is growing daily, so the test can be done already a few days after IVF. But on the second day after the procedure, it should not be carried out, since the amount of hCG is still not enough to draw any conclusions.

If on the 14th day after the implantation of the embryo the hormone level does not exceed 5 mU / ml, the procedure was unsuccessful. At 25 mU/ml, an additional check is made, since this result is doubtful.

These preparation methods will increase the effectiveness of IVF -

HCG norms

Chorionic gonadotropin is found in the blood and urine. The sensitivity of modern test strips is so high that it can capture even a small amount of the hormone. With the help of digital tests, you can determine not only pregnancy, but also its term: 1-2, 2-3 or 3+.

The level of hCG in the blood should correspond to the indicators given in the table. He can be:

  • minimal;
  • average;
  • maximum.

The values ​​of hCG during pregnancy after IVF in the table are given by the days that have passed since the implantation of the embryo (DPP). There are no indicators for 3, 4 and 6 days.

Important! Any indicators, whether it be 55, 230, 600, 806, 1890 or 3400, need to be evaluated only in relation to the number of days after planting. By themselves, these figures only indicate elevated level hormone in the blood and the presence of pregnancy.

On day 11, the indicator is 45 mU / ml maximum, and after 24 hours it is only average. At the same time, even 35-36 mU / ml is not a reason for despair. The main thing is that the level exceeds the norm and continues to grow.

This IVF method is effective even with deviations in the spermogram -

On day 16, the minimum hCG indicator in the table is 68 mU / mol, the average is 260, and the maximum is 400. On day 18, the values ​​​​increase to 220, 650 and 840, and on day 19 - up to 370, 980 and 1300 mU / mol.

The hCG table by day after IVF will help determine the gestational age based on the results of the analysis. For example, the average for 21 days is 1960 mU / ml, but a spread within 960 and 3100 mU / ml is quite acceptable. For 22 days, the average value is 2680, but fluctuations in the range of 1050-4900 mU / ml are possible. After another day, the minimum value is 1440 mU / ml, and by day 26 the hormone level can reach 4200-15600 mU / ml.

There is another hCG table for IVF - by week. It is much more convenient for checking hormone levels in the later stages. However, not everything is so clear with her. There may be cases of a slow increase in the content of hCG in the blood, so the test results are not always reliable. Most often this happens due to late implantation.

Since embryos do not have a clear schedule, modern science can only determine the approximate time of fertilization, the achievement of the ovum by the ovum and the introduction into its wall of the embryo.

Time from conception (in weeks) HCG level (in mU / ml), minimum-maximum
1_2 25-156
2_3 101-4870
3_4 1110-31500
4_5 2560-82300
5_6 23100-141000
6_7 27300-233000
7_11 20900-291000
11_16 6140-103000
16-21 4720-80100
21-39 2700-78100

It has been proven that hCG levels increase more slowly after IVF than after natural conception. This is due to the fact that with in vitro fertilization, implantation occurs later - approximately 10 days after the transfer. Accordingly, with IVF, a pregnancy test should be done a few days later. And it is important to take this feature into account when deciphering the results of the analysis yourself.

In the case of twins, the hCG content is twice the average values ​​\u200b\u200bgiven in the table, since two embryos develop in the uterus. This allows doctors to determine multiple pregnancy. The analysis results can be distorted by:

  • diabetes;
  • severe toxicosis;
  • gestosis.

That's why the IVF procedure with a donor egg is popular -

Why is hCG rising slowly?

An increase in the amount of chorionic gonadotropin is the main indicator of pregnancy.

And don't get hung up on his level. Even if it is below the data given in the table, do not panic.

Even a slow increase in the level of the hormone indicates the growth of the embryo.

There are several reasons for the slow growth of hCG. The most common ones are:

  • problems with the thyroid gland;
  • chronic or recent diseases;
  • individual characteristics of the woman's body.

Important! Only a doctor can determine the exact cause of the slow rise in the level of the hCG hormone. Do not take any action without consulting him.

A drop in hCG is an alarm signal that may indicate:

  • frozen pregnancy;
  • spontaneous abortion;
  • miscarriage;
  • ectopic pregnancy.

You should not panic ahead of time, because a decrease in hCG does not mean that IVF was unsuccessful. Placental insufficiency and the threat of abortion can also lead to a decrease in the level of the hormone in the blood.

These conditions are dangerous, but they are corrected with medication if timely measures are taken. That is why it is best to do tests in the same center where IVF was performed, so that the attending physician can promptly prescribe therapy - a complex of drugs to maintain the embryo.

Can analysis be false?

If the analysis data differ significantly from the values ​​\u200b\u200bgiven in the hCG table by day after IVF, this is not yet evidence of an error. The reason, most likely, is the use of other technologies and reagents by a particular laboratory, and therefore the result turned out to be different from the average values.

Naturally, no one is immune from the mistakes of laboratory assistants, but in modern clinics where latest equipment, human factor practically excluded. In any case, it is best to show a doubtful result to the attending physician so that he can explain it or send it back for analysis.

Quite often, a non-standard indicator of the hormone level indicates a woman’s poor health, in particular, the presence various diseases. For example, low levels of hCG occur with ovarian dysfunction, which does not interfere with the normal development of pregnancy.

As practice shows, in many women, the level of the hormone chorionic gonadotropin did not correspond to the norms prescribed in the table, and most of them successfully did IVF and knew the joy of motherhood.

Only in these cases is the PICSI procedure indicated for IVF -

If there is any doubt, it is better to do the analysis again. Firstly, the second result will be more accurate, since the content of hCG in the blood is constantly growing. Secondly, such a solution will eliminate the possibility of error.

Although both home use test strips and laboratory blood tests are based on the determination of the hormone chorionic gonadotropin, their readings may not match. Most often there are cases when the test gives a negative result, and the analysis is positive. It happens when a woman does a rapid test too early or uses the strip incorrectly.

Video

HCG is a unique hormone that is secreted by the chorion of the embryo and enters the body of the expectant mother. Pregnancy and its exact term are determined by its level in the blood. With the help of those tests that are sold in a pharmacy, the presence of this hormone is also determined, but already in the urine. There, the concentration of the hormone is half that in the blood, so pharmacy tests are considered less informative than a laboratory blood test.

After IVF, such a procedure is carried out after 2 weeks to determine whether the fertilized egg is fixed on the inner surface of the uterus.

HCG rates during IVF pregnancy by week: table

Chorionic gonadotropin is secreted by the chorion, so a non-pregnant woman should not have it in the blood. If the analysis is positive, but there is no pregnancy, it is assumed that shortly before this, the woman experienced an abortion or fetal fading at an early stage.

If this was not the case, we can assume the formation in the body malignant tumor, which releases cells into the body that are similar in structure to the hCG hormone. In world medical practice, there have been cases when, for fun, men took a pregnancy test, and it turned out to be positive. So patients accidentally learn about serious health problems.

After IVF, it is necessary to control hCG, which changes with the course of pregnancy. Starting from the first day of fertilization and up to 11-13 weeks, there is a constant increase, then there is a gradual drop in the level of hCG.

There are hCG norms in diagnostic centers, but they are approximate. The norm of the hormone in a particular woman may differ from the general indicators. This is due to the fact that each pregnant woman has her own body constitution, her own body characteristics and can endure pregnancy in different ways. That is why the doctor often compares the results of hCG not with “general standards”, but with earlier hormone levels in the patient. In other words, the dynamics of hCG is monitored relative to individual results, and the presence or absence of an increase is determined based on the past results of the analyzes of this woman.

Please note: HCG testing labs use different reagents, instruments, and equipment, so test results may vary slightly. Sometimes it is advisable to repeat the analysis in several diagnostic centers at once in order to get an accurate picture of the course of pregnancy.

In gynecology and obstetrics, it is customary to count in weeks, and the countdown is not from the day of conception or the IVF procedure, but from the day the last menstruation began. This is the so-called obstetric period of pregnancy. However, the level of hCG begins to increase only after conception, therefore, to determine it, it is often taken not obstetric, but the embryonic period, which is considered from the day of fertilization.

Future mothers who do not know such features are confused about the timing and may misinterpret the results of hCG. That is why it is important to consult a doctor in time. If you urgently need to decipher the hCG result and there is no way to immediately visit the clinic, check with the laboratory where the analysis was performed, the hCG norms for your gestational age with the obligatory indication of whether the laboratory takes into account the obstetric or fetal period.

To illustrate how the level of hCG may differ depending on the same obstetric and fetal period, we provide a table of hCG norms during pregnancy by week.

Gestational age

(weeks from conception,embryonic period)

Gestational age

(weeks from the first day of the last menstruation,obstetric term)

The norm of hCG, mIU / ml
3-4 5-6 1 500-5 000
4-5 6-7 10 000-30 000
5-6 7-8 20 000-100 000
6-7 8-9 50 000-200 000
7-8 9-10 40 000-200 000
8-9 10-11 35 000-145 000
9-10 11-12 32 500-130 000
10-11 12-13 30 000-120 000
11-12 13-14 27 500-110 000
13-14 15-16 25 000-100 000
15-16 17-18 20 000-80 000
17-21 19-23 15 000-60 000

Below is a table that reflects the dynamics of hCG by week during IVF pregnancy.

Gestational age

(weeks from conception, embryonic period)

The norm of hCG, mIU / l
1-2 25-156
2-3 101-4 870
3-4 1 110-31 500
4-5 2 560-82 300
5-6 23 100-141 000
6-7 27 300-233 000
7-11 20 900-291 000
11-16 6 140-103 000
16-21 4 720-80 100
21-39 2 700-78 100

Please note that the norms given in the table are the norms of a single laboratory. HCG levels in other diagnostic centers may vary. The interpretation of the results of the analysis is carried out by the doctor.

HCG in multiple pregnancy after IVF

Often, during IVF, the expectant mother is implanted with several prepared embryos in order to increase the chances of success of the procedure. There are cases when all fertilized eggs take root. In this case, a multiple pregnancy occurs. It is determined by ultrasound at 11-12 weeks, but a high probability of carrying twins can be detected when donating blood for hCG. In women carrying twins, this figure is significantly higher than the norm.

Low hCG during IVF pregnancy

Low levels of hCG after IVF may indicate a lack of pregnancy, a threat of miscarriage, or, therefore, values ​​​​below the norm should alert the patient. The analysis is repeated several times, tracking the dynamics of changes in indicators.

A sharp decrease in hCG during pregnancy after IVF

After IVF, you need to monitor the level of hCG during the first trimester, when the likelihood of a missed pregnancy is high. If there is a sharp decrease in the level of this hormone after IVF, this is a reason to immediately contact your doctor. Sharp jumps in hCG indicate a high threat of interruption. The patient is sent to the hospital for preservation, having previously done an ultrasound to check the heartbeat of the fetus.

Constant monitoring of hCG levels helps to identify certain problems and risks before they make themselves felt in the form various symptoms. The earlier a problem is identified, the easier it is to fix it.

  • Why do you need HCG during pregnancy?
  • Why HCG levels are too high or too low

The first days after the in vitro fertilization procedure are the most exciting for both doctors and expectant mothers. I want to know the result as quickly as possible, and this can be done by monitoring the level of the hCG hormone - human chorionic gonadotropin.

What indicators of hCG analyzes indicate the onset of pregnancy and why they cannot be completely trusted - the answers are in our material.

Human chorionic gonadotropin begins to be produced by the shell of the embryo after implantation in the uterine wall. It is the moment of implantation (and not the fertilization of the egg) that should be considered the beginning of a successful pregnancy. Obviously, in a non-pregnant woman, the levels of the hCG hormone will be minimal - no more than 5 mU / ml. But as soon as pregnancy occurs (the embryo is implanted in the wall of the uterus), hCG levels practically double every 48 hours up to 11-13 weeks.

How is HCG measured?

Results are measured in "international units" (IU) or simply units (U). This is the same! The amount of hormone can be normalized per liter or milliliter.

Why do the results of analyzes made in different places differ?

The data obtained in different laboratories may differ significantly - they depend on the equipment, methods and reagents used in a particular institution. There are no single "correct" numbers - you and your doctor should be guided by the scale normal indicators the laboratory that performed the analysis.

Why do you need HCG during pregnancy?

Human chorionic gonadotropin is vital for the normal development of pregnancy.

    HCG maintains the functioning of the temporary endocrine gland - the corpus luteum, which stimulates the growth of the endometrium (the inner layer of the uterus) and prevents the release of new eggs and menstruation.

    HCG stimulates the production of hormones (progesterones and estrogens) that act on the inner layer of the uterus to ensure the successful implantation of the fetal egg.

    HCG reduces the immunity of the mother, which can provoke rejection of the fetal egg.

    Finally, hCG is directly involved in the development of the gonads and adrenal glands of the fetus.

We can say that human chorionic gonadotropin is a kind of "trigger" that starts the mechanism of carrying a pregnancy.

Do I need to additionally administer drugs containing hCG during IVF?

If this hormone is so important in IVF, then perhaps it is worth introducing it into the body artificially? This is a fairly common practice, although it raises serious doubts among fertility doctors today. Many of them believe that exogenous (that is, introduced from the outside) hormone does not improve the situation with embryo implantation, although it does not significantly affect a successful pregnancy. In this matter, you should trust your doctor.

HCG and pregnancy test strips

Since hCG is a specific substance that is produced mainly in women during pregnancy, the effect of home pregnancy tests is based on its detection. However, they are not very well suited for such a difficult situation as pregnancy as a result of IVF. Firstly, the content of the hormone in the urine is approximately half that in the blood, therefore, in the very early stages, the tests simply “do not see” the pregnancy - they react to the hCG level of about 25 mU / ml. And secondly, it is a qualitative test that gives only a yes-no answer. Meanwhile, monitoring the concentration of hCG during the first weeks of pregnancy can tell a lot to a specialist.

What does the doctor see when he looks at tests for hCG after IVF

All people are different, so the results of tests for women at the same stage of pregnancy will vary, sometimes at times. Indicators depend on individual characteristics.

The first test, done within a week of embryo transfer, will show a sharp rise in hCG concentration, indicating that pregnancy has occurred. Subsequent tests will show the development or spontaneous termination of pregnancy. The readings can vary, so don't worry if another woman at the same gestational age is higher or lower than yours. The fact that IVF is successful will only be indicated by a relative comparison of the hCG level in a series of tests.

So, the first reliable results can be assessed after 7 days from the moment of conception. Further, the level of chorionic gonadotropin should rise sharply up to 10 obstetric weeks. After the concentration of hCG begins to gradually decrease and stabilizes at 20-21 weeks.

"Obstetrical" and real gestational age

In obstetrics, the gestational age is counted from the day the last menstruation begins. This is the so-called "obstetric" period of pregnancy. But the level of hCG begins to increase, of course, not from the moment of the onset of menstruation. Check with the laboratory where the analysis was performed, the laboratory indicates the obstetric or embryonic period in the list of normal indicators.

Why HCG levels are too high or too low

Above the norm of hCG, as a rule, it happens in one case - a multiple pregnancy. With IVF, this happens infrequently, yet today, reproductologists try not to take risks and plant only one embryo.

Very rarely very high level HCG indicates the development of a rare complication that accompanies a non-viable pregnancy - .

It often happens that the level of hCG is below normal. If it has not increased, then, unfortunately, this attempt of in vitro fertilization is unsuccessful, the embryo was not implanted. Do not immediately despair - sometimes an impatient expectant mother does the test too early, before the implantation of the fetal egg, and the next analysis will show the growth of the hormone. Too slowly rising levels of hCG may indicate an ectopic pregnancy, and sharp jumps in the concentration of the hormone - about or the threat of interruption. However, only a doctor can evaluate the results of tests and the dynamics of changes in indicators.

Let's repeat again important points that the expectant mother should take into account.

    HCG level after IVF control during the first trimester pregnancy.

    D the dynamics of changes in the level of hCG is more important than "exact hit" in the normative values. If the level of hCG doubles every 48 hours - most likely, the pregnancy has come and is developing normally.

    Choose one lab for testing and do tests in it. In different institutions, the results will differ depending on the equipment used and research methods.

We wish you a happy pregnancy and excellent tests!

Prepared by Anastasia Sergeeva

The main indicator of the onset of pregnancy is the level of hCG in the blood of a woman. Methods for determining the presence of a hormone are a pregnancy test, as well as a blood test. It is necessary to consider in more detail the norms and rates of increase in hCG during IVF.

HCG (human chorionic gonadotropin) is a hormone that increases significantly during pregnancy. After fertilization of the egg and the formation of the placenta, the number of hCG begins to double rapidly. This factor is a positive sign of a successful pregnancy.

During the IVF procedure, the development and growth of hCG are the main components of the onset of an artificially obtained pregnancy. The norm is a constant increase in the hormone until the 12th week of pregnancy. Having reached the maximum value of hCG, it begins to decline to a certain point.

Carrying out a blood test for the content of hCG

The onset of pregnancy after embryo transfer can be ascertained after two weeks. But at the same time, it is possible to conduct a special blood test for the level of hCG, controlling its dynamics and growth.

The norms of hCG in the blood

In order to determine successful fertilization during IVF, you should know the minimum, maximum hCG values ​​in units of measurement (mIU / ml).


A positive hCG number is not a 100% guarantee of pregnancy, so ultrasound control will give an accurate answer. The specialist will control the development of the process, exclude an ectopic pregnancy, and also check the number of attached embryos.

Normative table of hCG after IVF

A special blood test for hCG levels after embryo transfer must comply with established standards to determine the success of the process. Below is a table of hCG values ​​at different times and the dynamics of its growth.

Number of days after transfer Embryo age before transfer The norm of hCG in units of measurement
3 days Day 5
7 4 2 3–12
8 5 3 4–22
9 6 4 6–26
10 7 5 10–28
11 8 6 12–50
12 9 7 21–70
13 10 8 24–110
14 11 9 32–180
15 12 10 42–300
16 13 11 75–420
17 14 12 130–510
18 15 13 225–900
19 16 14 420–1500
20 17 15 630–2100
21 18 16 830–3300
22 19 17 1200–5100
23 20 18 1500–6500
24 21 19 2150–8000
25 22 20 2600–10200
26 23 21 4700–16000
27 24 22 6000-20000
28 25 23 8700–28500
29 26 24 9400–35000
30 27 25 12200–42000
31 28 26 13000–62000
32 29 27 13900–70000
33 30 28 15200–72000
34 31 29 16000–78000
35 32 30 18600–84000
36 33 31 20050–90000
37 34 32 21300–96000
38 35 33 22900–101000
39 36 34 24900–110000
40 37 35 27000–120000
41 38 36 29000-124000
42 39 37 30000–129500

Rules for using the table

Determining the noma of the level of hCG in the blood is done quite easily using some calculations.

  • The exact date of the study. It is necessary to determine by the age of the embryo (3 days or 5 days), then calculate the number of days after the embryo transfer. Next, check the value against the table;
  • To calculate the exact number of days after transfer, use the column with the desired embryonic age. If this factor is not taken into account, then the hCG value will be incorrect;
  • The last column of the table shows the approximate average value of the normative content of hCG in a woman's blood. Therefore, in case of any deviations, you should consult a doctor, and not draw independent conclusions!

Therapy with hormones

Pregnancy after IVF is often accompanied by threatening symptoms. These include: low level HCG, bloody discharge, pulling pains in the uterus. If these signs are present, the leading gynecologist should prescribe complex therapy aimed at maintaining pregnancy.

The main methods of prolonging pregnancy after IVF:

  1. Administration of the hormone progesterone. Progesterone is the pregnancy hormone responsible for its successful course. With IVF, the level of hCG may not be high enough, so it is recommended to take drugs containing the hormone progesterone. The most popular drugs are duphaston and utrozhestan. But exact dosage, the period of taking the medicine should be prescribed only by the attending physician!
  2. Complex vitamin maintenance therapy. To maintain pregnancy, doctors also prescribe vitamin E, folic acid, hemostatic drugs as needed, magnesia droppers, food rich in valuable trace elements and substances.
  3. Compliance with a moderate rhythm of life. After the transfer of embryos and the onset of pregnancy, a woman is recommended a quiet life schedule. Avoid extreme sports, strong physical exercise, nervous disorders. You need to limit your stay in public places to avoid infectious diseases like a cold or flu. Immunity is very weakened, as the body begins to work for two.

Signs after IVF with an increase in hCG

It should be noted that there are no special signs of an increase in hCG. If a woman feels any changes in the body, then they are not always an accurate confirmation of the onset of pregnancy.
You can test for hCG levels during IVF no earlier than two weeks after the procedure. The gradual growth of the hormone is controlled by a constant study of the content of hCG in the blood, but this should be done almost every day. If there is a threat of non-pregnancy during IVF, doctors prescribe this test in order to conduct maintenance therapy for successful implantation of the embryo.

Methods for determining the growth of hCG

For control general condition after IVF, several indirect methods can be used to determine the level of the hCG hormone.


When summing up, I would like to say that thanks to modern medicine, the desire to become parents in the absence of a physiological possibility is quite feasible. You just need to try hard, have a great desire and always move forward!