From the moment of conception to the birth of a child, two cells in the beginning give rise to a huge number of unique processes. Any future mother is interested in knowing what is going on inside her, how the fetus is formed. And the mother who resorted to eco and even more so. Therefore, women always want to carefully study the development of the embryo by day after the transfer in order to visualize the desired result as accurately as possible.

Embryo cultivation

After the union of the gametes of the spouses (egg and sperm) begins to emerge new life. The unique process of creation thanks to scientists is available under a microscope. The development of the embryo on the days before the transfer takes place in a special environment - a Petri dish. The process takes from 3 to 5 days, depending on when the embryo transfer is scheduled. After replanting, the uterine stage of fetal formation already begins.

12-16 hours after the connection of male and female cells, the first assessment of the unborn child is carried out. The initial development of oocytes after IVF is very important. At this stage, the formation of the future karyotype begins - a connection of chromosomes is formed, which are responsible for all processes in the body, gender is established.

In medicine, all stages of fetal formation have names - zygote, morula, blastocyst, gastrula, embryo, fetus. The stages of development of embryos after transfer by day begin with a morula or blastocyst. It depends on which day the transfer was made.

Zygote. Sharing is a key element of any life. On the second day, the fertilized egg begins to divide into 2-4 cells, by the third day they become 6-8. The cells into which the embryo breaks down are called blastomeres.

Development analysis at this stage is determined by the following factors:

• total number of blastomeres;
• number without nuclei (anuclear blastomeres);
• evaluate their shape and size.

The first labeling of the embryos is carried out. The letters (A-B-C-D) indicate the quality, and the numbers indicate the number of blastomeres. For example, 4A is an embryo of excellent quality, with 4 blastomeres, 6D is a six-cell embryo of unsatisfactory quality (more than 50% of anuclear blastomeres).

Development after the transfer

Morula. By the end of the third day, most embryos with genetic damage stop developing. This happens because up to this point the formation took place due to the nutrients of the egg itself, then the genetic apparatus starts up and the embryo behaves according to the program of natural selection. Surviving embryos continue to divide, the number of blastomeres reaches 10-16.

The process of compaction starts - intercellular bonds are strengthened, the surface of the cells is smoothed. The next stage of quality assessment is underway. If there are risks of stopping development at the morula stage, a decision is made about the possibility of transferring it to the uterus. It is generally accepted that in the body of a woman the chances of survival increase.

The development of 3-day-old embryos after replanting normally does not differ from that if they continued to be cultivated in the medium.

On the 4th day from the moment of fertilization, the process of compaction is completed, the blastomeres are divided into two groups - the cell mass and the trophoblast. The first of them will give development to all organs and tissues, the other will form extra-embryonic membranes - chorion, amnion, allantois, yolk sac, trophoblast will also play a decisive role at the time of implantation.

Blastocyst. Inside the morula, with the moment of separation of the blastomeres into groups, a cavity appears. When it reaches half its size, the embryo is already called a blastocyst. The chances of survival are higher for those blastocysts in which the cavity is larger and both groups of blastomeres are better formed.

Then the development of a 5-day-old embryo continues according to the scheme - the cavity increases, the transparent shell stretches and breaks (hatching). The blastocyst is now ready for implantation. A transplant is carried out in the uterus. Next, the development of the embryo begins by day after the transfer of 5 days.

Gastrula. On the 6-7th day after the fertilization of the egg, or on 3-4 DPP of 3 days, or on 1-2 DPP of 5 days, the process of implantation begins. The blastocyst adheres to the mucous membrane, the trophoblast begins to form villi that help to penetrate deeper into the endometrium.

Closer to the 9th day of PO, the process of implantation is completely completed, the embryo is completely immersed in the uterus. Next starts complex mechanism the formation of the placenta, the formation of future organs of the embryo, extraembryonic membranes, production begins hCG hormone. Every day its level grows and on the 14th day after fertilization, pregnancy can sometimes be diagnosed. Now the embryo is fully called an embryo.

Important information on the development of embryos

What happens to the embryo after transfer to the uterus by day? In the absence of negative factors, every day the embryo develops safely. If at any stage deviations in the genome occur, the impact of the artificial environment for cultivation affects, or there are processes in the woman’s body that prevent its growth, then the chances of survival are small, “natural selection” occurs in the uterus.

How does the embryo develop after transfer to the uterus by day? If a 3-day-old embryo was implanted, then it is logical that, first of all, it reaches the blastocyst stage. After that, the development of the embryo after transfer to the uterus by day has the same pattern for everyone.

Why don't embryos develop after transfer? Among the reasons that stop the growth of embryos in the uterus may be the unwillingness of the endometrium to accept foreign body, various endocrine, immune and other problems of the patient. Unfavorable factors are also stressful situations that lead to tachycardia.

Such palpitations after embryo transfer may also be due to complications with the ovaries, which will also negatively affect implantation. But, most probable problem as the embryos themselves, on average it is 80% percent of all failures.

To eliminate the risks of obtaining a low-quality embryo, even at the stage of pregnancy planning, modern trends in genetics in in vitro fertilization are used. Genetic testing of parents at different levels (the entire genome or several genes) will determine the risk of getting pathologies in the unborn child, not only after birth, but also those that may appear with age. And the method of PGD - preimplantation genetic diagnosis, will determine deviations in the set of chromosomes before embryo transfer.

No matter how scary it may seem, in vitro fertilization works. After positive analysis HCG many women have become happier. And they are looking forward to the time of the ultrasound to confirm the onset of pregnancy and in order to hear their baby for the first time.

Which one can hear the heartbeat? The first ultrasound after hCG analysis is scheduled for 21-24 DPP. As a rule, it determines only the presence of a fetal egg, the place of its attachment. And only at the next ultrasound examination, after a week and a half, a heartbeat is visible at an average of 35 dpo.

Further development of the fetus can also end in different ways. Basically, after the positive results of the first ultrasound, a woman diagnosed with pregnancy after IVF is observed, like any other. At this stage, the options for the course of pregnancy are the same.

Features of hCG after IVF: how it affects the onset and maintenance of pregnancy. HCG table by day after IVF: norms

Pregnancy is a state, each stage of which is clearly regulated by its own hormones. The process of gestation as a result - IVF - also needs hormonal regulation. Not always the mother's body is able to independently provide the necessary level of hormones.

Analyzes after IVF allow you to determine the growth rate of active substances, if necessary, correct them with drugs. But some hormones are an indicator of a normally developing pregnancy. For example, hCG after IVF in terms of growth rates can tell about the course of gestation, the likely threat of interruption, or, for this, it is enough to compare the results with the table.

• The role of hCG in IVF
• The first signs of pregnancy after IVF before hCG
• Allocations
• What is the dynamics of hCG after embryo transfer
• Interpretation of analysis results
• HCG table by day after IVF: normal
• What does he say low level hCG
• The reasons high level HCG early and late
• Ultrasound control
• Prescribing hCG in injections after embryo transfer in IVF protocols

The role of hCG in IVF

For the first time, a woman who decides on artificial insemination encounters human chorionic gonadotropin when ovulation is stimulated. This procedure is performed for those who have regular unprotected sex, many women over 35 years of age and those who, according to the results of ultrasound, have abnormal development of the follicles or corpus luteum.

When stimulating ovulation, only an injection of hCG can be used. It is administered if, according to the results of ultrasound, the follicle matures, but its shell cannot rupture on its own and passes into or regresses.

Another stimulation scheme involves taking Clomiphene preparations, which stimulate the production of FSH and LH. These hormones ensure the maturation of the follicles. When, according to ultrasound, they reach a size of 17-18 mm, they give an injection of hCG. This hormone provokes the maturation of oocytes, the rupture of the membrane and the release of the egg. 24 hours after the injection, the woman is ready to produce and collect eggs. If the moment is missed, the follicle will rupture on its own and the oocytes cannot be collected.

Some protocols provide reintroduction HCG, if the size of the follicles has reached 20-25 mm, and the rupture has not occurred. Sometimes a hormone is needed to support the corpus luteum. But the dosage of such injections is very small - 300-1500 IU. drug overdose, frequent use lead to early menopause.

Signs of pregnancy after embryo transfer before hCG analysis

An analysis for hCG is prescribed after 14 days. But many women, even before a blood test, feel the symptoms and the first signs of pregnancy after IVF:

• irritability, sudden mood swings;
• sleep disorders;
• headache, fatigue;
• that appear earlier than with natural fertilization;
• engorgement of the mammary glands;
• pain in the pelvis, in the ovarian region;
• lowering blood pressure;
• tides.

Allocations before hCG analysis: menstruation or implantation bleeding

Some may experience spotting. This is implantation bleeding, which occurs as a result of the dissolution of the endometrial vessels by the embryo. It should not be plentiful and long. But it is possible to accurately establish the fact only by the results of ultrasound and analysis for hCG.

Embryo implantation does not occur simultaneously with its replanting in the uterus. This usually takes up to 6 days. But sometimes a fetal egg cannot find a suitable place in the wall of the uterus for a long time, then it happens 10 days after planting. It does not affect this in any way, but hCG will also begin to rise later.

So, by the age of 4 months, we had quite a lot of fun.
Firstly, the baby has finally learned to roll over from its back to its tummy on its own. And then kapets - as soon as you arrange him on the rug, you only move away for a second ... Hoba - and the little one is already lying on his stomach, the rug scratches with his little hands, stares around. Yes, only Lyoshka does not know how to roll back yet, so he gets tired and digs the surface with his nose, is naughty.
Secondly, we continue to have diathesis; (((The cheeks have already been cured, but the rash periodically appears here and there ... In the clinic they said - I'm bad, I eat damn it. But in fact I'm just dying of hunger, I want so much sweets - I tear the roof. Constantly hungry, in stores at the checkout, I’m ready to faint at the sight of all kinds of chocolates and others like them; (((And now you also need to give up dried fruits and sweet cheeses. Again cereals and kefir. Let's endure!If only starvation did not affect lactation.
The umbilicus is still weak, but they allowed to take a break in gluing with a plaster, because. already irritated skin around.
The BCG vaccine never showed up. Weird, but okay. This sort of thing happens.
They didn't get a new DPT shot. First, there is no vaccine. Yes, yes, it happens! Well, diathesis needs to be treated, it is impossible to vaccinate with exacerbation.
The little one eats very badly, constantly with scandals - sometimes she cries, sometimes she is indignant, sometimes she turns her head in all directions, then she falls asleep ... I already wait for each feeding with fear - what will he conjure up?
Well, at least he likes to swim.
They thought that whims were connected with the teeth. An no. We don't have teeth yet. Oh!
In case of a tantrum, a rocker with "white noise" and a nipple greatly save.
We weigh 7900 g (gained a little more than a pound). But they came out with a sprout - already 66 cm!
Yes, it's difficult with the little one. But it's so wonderful that my sweet child is next to me, even if I take offense at him for whims. What to do? It is also hard for him - the world is too big and mysterious, but complex. How to deal with everything? Only with my mother's constant help and support.
I'm really trying!

Yes, exactly one year ago I found out that I was pregnant ;)))
How it was...
3 DPP
Saturday and Sunday flew by unnoticed, now to endure the working week. We didn't go out much on weekends. I fiddled around the house and tried to lie more, but without fanaticism. I read it, good - there are a lot of books, and all of them are interesting. I watched films at the same time as embroidery. Now I am embroidering a beautiful picture - it is called “fairy-mother”. There, like a woman with wings, holding a baby with wings on outstretched arms too! So cute! Last time, I also embroidered all sorts of "children's" embroideries, and then abandoned them - morally I could not. Switched to neutral. And now it's okay. What will happen if the span is scary even to think ... Dimka constantly reminds me that I perceive everything without tantrums. And in general, he refuses to talk about the fact that there was a transfer, that we are waiting for the result. It's probably easier for him.
I noticed that, like last time, I have a slight tingling in the area of ​​\u200b\u200bthe uterus, especially if I walk a lot or lift something heavier than a couple of kg. But this is not an indicator - it was the same in the transit cryo.
I'm not looking for any signs - it's early. And it’s pointless to do the test before the weekend, because I pricked the horagon.
The doctor warned me not to constipate. And since I suffered a lot last time, now I decided to drink dufalac right from the beginning of taking progesterone. Yes, not like before - 30 ml once a day, and 25 ml twice a day - in the morning and in the evening. Helps.
4 DPP
I fall asleep instantly, but I don’t sleep well - I toss and turn from side to side, I constantly run to the toilet - enuresis or what? Feeling normal. It even scares me. The chest does not fill. The stomach occasionally sips, but so quietly that if I had not listened to my body so sensitively, I would not have felt it. Or maybe I'm winding myself up? Yesterday there was a small temperature after dinner - 37. Since yesterday, I started drinking aspirin 75 mg. I'm afraid the blood will thicken. It's so scary that words can't express it. I think - should I buy a test today? There is one at home, in a box with striped ones from the previous protocol. Sort of like "charging". I shot progesterone in the morning - unsuccessfully, it seems, a bit low - almost right in the softest place, but I should have aimed higher. Now it hurts. I can't find my place. I started drinking valerian.
5 DPP
No feelings. The chest didn't even fill up. Last time, I remember, my stomach felt so good. Then it worried me. Now worries that it does not pull. I was looking at pregnancy tests at the pharmacy yesterday. But the courage to buy was not enough. And today I will buy. I will still pee on Saturday and Sunday, regardless of the result, so I will need more than one.
Last time, on the same day, I had a slight bleeding, such as implantation. After that, I was 90% sure that everything worked out. That's what Dima said. And now... There is no bleeding.
I think that my baby has endured so much - cryo, biopsy, and did he really not stay with me ??? I know that I wind myself up ahead of time, but the temperature is raised from progesterone, the head is hot and somehow heavy. I'm afraid of everything.
6 DPP
There was no implantation bleeding. In general, I feel healthy, like a horse. The chest does not fill up, it only itches, it has become sensitive. But the hormones in my body are clearly in excess - it’s already starting to feel sick, especially from different smells. And at work, as luck would have it, one or the other stinks.
I made an injection today in the "far" half. Good luck. The past hurts a lot. If it doesn’t stop hurting before the next cool date, then I’ll do it again today.
I read that in all successful protocols, the stomach must be pulled. And I only have light tingling in the area of ​​​​the uterus, and I also want sex, well, something itches there. Kapets! Sometimes I feel like I'm just imagining this. Horror! How to survive all this???
The belly is not very inflated. But slightly enlarged.
I check my feelings with Iryny in her success. Does not look like it.
I read: "Implantation bleeding is the exception rather than the rule - it is rare." Calmed down a little. And I even found answers from women who had EC during their first pregnancy, and did not have it during subsequent ones.
Bought a test yesterday.
7 DPP
Still, yesterday there were clearer sensations in the lower abdomen. Some sharp pulling, tingling. But it doesn't look like an intestine. It works fine for me this time.
There is already a lot of progica in the blood, so I react to all smells. But this is not a sign - so I have every time on hormones.
I sleep badly. More precisely, I fall asleep well, and then I start running to the toilet (today I ran 2 times - at 1 a.m. and at 3 a.m.), and then I barely lay down until 6, didn’t sleep from 5 - tossed and turned from side to side, thoughts tormented me.
This morning, the stomach is clearly inflated, sometimes it sips a little. Earlier in the morning it was smaller. The chest is also slightly puffed up, especially the nipples are sensitive.
8 DPP
Although I tried to go to bed later yesterday, so as not to cuckoo from 5 in the morning, but still at 22.30. sleep overcame me. Therefore, at 5 I was no longer sleeping, I was lying and was afraid. I thought - to get up or not to get up, it's scary! I remembered my mother telling her that everything would be fine with me, and asked her to help me get through all these worries. I talked with the baby about how much I love him, and how much we need him. Got up at 6 o'clock bladder already burst. And I didn’t seem to drink at night, and at 1 am I was already running, but I wrote out a liter in a jar !!! And I even finished pissing down the toilet. Kapets. I took an evitest, soaked it. He was white. I waited a little from past experience, and the ghost of the ghost of the second strip appeared. At first it seemed that it was streaked in my eyes. Every 5 minutes I ran up and checked - did my ghost run away ??? As soon as it cleared up on the street, I tried to look in this light. Something is clearly there - but very pale. If these are not the remains of Horagon (8 days have passed, in theory, the level in the blood from 5000 should already be 5-7 units, in the urine - even less). But with hCG = 7.3 I didn’t even have a ghost, and Ira had a white test even at 20 in cryo. Therefore, I try to believe that this is IT. Maybe the concentration is so low because I pee in liters?
Tomorrow morning I will definitely soak again. I hope my ghost becomes clearer...
I felt as healthy as a horse. Although Dimka upset me - he did not want to go for a walk to the center (to the exhibition of violets and in Maccafe - for the coveted macchiato), I even cried a little. I decided to go shopping in the area myself - I bought myself an eyeliner, a sea-green blouse and plums. I came home happy, and suddenly ... I found a red spot on the panties the size of the head of a tablespoon. It darkened in the eyes, even threw it into a fever. The stomach instantly began to whine, the chest ached. Well-being - exactly the same as during menstruation. I injected dicynone, put a papaverine candle, drank dufaston and proginova extraordinary and curled up on the bed. Dimka noticed and asked. I told. I honestly thought it was a breakdown. The blood was red. Thoughts are bad - is it really from the fact that I partially replaced injections with pills? Or was it just that the morning ghost was still from Horagon, and the embryo did not initially take root ??? She cried out rivers of tears, Dimka consoled, said that we would still achieve our goal.
By the evening, I began to remember that the last time I had implantation bleeding, it seemed not at 5 DPP, but on Friday, i.e. at 7 dpo… maybe it was again?????????? I read that this thing is hereditary. I was crying, my mother was gone, I didn’t even have anyone to talk to ... Mom would have known. It seems to me that she said something like that, they say, she bled on the expected day of the cycle during pregnancy. But I myself don’t understand where the truth is, and where I myself came up with as a consolation.
Probably, Fate cannot forgive me for something ...
9 DPP (October 23, 2011)
I put a large pad on at night, but it didn't shed anymore. I decided in the morning against all odds to do a test. At 5 in the morning I wrote a half-liter jar and put it in the toilet, and at 7 I got up and wanted again. Wrote another half a liter now in a mug. I was tormented whether to check in the first one (and suddenly it had already deteriorated) or in the fresh one. In short, I dipped both there and there. Luckily there were tests. Very these Evie "think long". First, clean, clean. But after all it is written - to check in 3-5 minutes. So I waited in tears. My ghost is in place. Even in the urine that was collected at 5 in the morning, he became less ghostly than yesterday, you can even show Dimka. Yesterday I did not dare - there was too pale a stripe, barely visible. She was afraid that he would only chuckle, saying that there was nothing there.
There are no more tests. Today we are going to the pharmacy with Dimka, we will buy it with a margin. I got hope. There can't be a ghost from Horagon today!!! I smeared divigel in the morning, so I found that on the strip in the lower abdomen (even in the very first cryo I had a barely visible strip from the navel down, it darkened during pregnancy, the hairs on it grew, but a little, after cleaning after 3 months it again became barely noticeable) - a dark hair grew right in the middle. The chest is sensitive, the lower abdomen no longer hurts so much, I drank no-shpu at night.

Much of a woman's knowledge of how pregnancy begins ends at the stage of ovulation and fertilization. Actually, the success or failure of the planning cycle is attributed to the fateful "meeting" of male and female germ cells. However, in the development of a new life in the body of a woman, there is another complex and important point - embryo implantation. In order to increase the personal literacy of planning ladies, this issue should be given special attention.

A bit of theory

Implementation fertilized egg into the uterus called implantation. The villi of the embryo penetrate the lining of the uterus, which can cause minor bleeding.

In order for implantation to be successful, several conditions must be met at once:

• lush three-layered endometrium with great content substances that feed the embryo;
• high amount of progesterone in the body (so that the embryo can develop and menstruation does not begin);
• normal microflora in the body.

The process of fertilization and development of the fetal egg- not one-time. And each of its stages is important for the onset of a normal pregnancy and the formation of a healthy fetus.

Timing of implantation

After ovulation and the meeting of the egg with the sperm, the fertilized zygote begins to move through the fallopian tubes. Her task is to get into the uterus as quickly as possible in order to gain a foothold in the endometrium specially prepared for this. On the way, the zygote continuously divides and grows. In stage blastocyte implantation and happens.

It is conditionally possible to distinguish middle, late and early implantation.

• Early. It occurs quite rarely. Usually, implantation is considered early if it occurs 6-7 days after ovulation (or 3dpo - 4dpo when it comes to IVF
• Average. 7-10 days pass between fertilization and implantation ( embryo implantation after transfer comes around 4-5 days). Doctors say that the introduction of morula takes about 40 hours, after which the body begins to produce the hormone hCG in the blood, it rises basal body temperature. Based on this, the so-called. the embryonic period of development, which lasts until about 8 weeks of gestation.
• Late. It occurs approximately 10 days after fertilization. This is what always gives women even a weak, but hope for possible pregnancy- even when you can't wait.

If pregnancy does not occur for a long time, then you need to be examined to identify the cause of infertility.

Subjective and objective signs

Both in the natural and in the artificial cycle, women are very excited and want to quickly open the veil of secrecy - is there a pregnancy or not? They start collecting symptoms and sensations, trying to find in their well-being some kind of relationship with reality. Experts took as a basis a simple classification, according to which all signs can be divided into subjective and objective.

Subjective:

• pulls the stomach;
• discharge;
• mood changes, emotional lability;
• tingling in the uterus after ovulation;
• feeling tired, etc.

Girls may even point out that after IVF, the stomach hurts like before menstruation. In this case, while there is no clear certainty, such pain may indicate both the onset of pregnancy due to successful implantation, and the approaching end of the cycle - and the beginning of a new one.

Objective:

• the basal temperature rises after the transfer (after a slight retraction in the natural cycle);
• body temperature after transfer can also increase from 37 to 37.9 degrees;
• detection of hCG hormone in urine and blood.

In this case, it is necessary to distinguish between the levels of pain, the abundance and saturation of secretions, an increase in body temperature. Sometimes what passes for implantation of the ovum signs are symptoms of some other disease. If you are in doubt whether your feeling 5 dpo signs fetal implantation or not, it is better to consult a doctor.

Embryo development by days after IVF

If everything is more or less clear with the natural cycle, then the question on what day does the implantation of the embryo occur in a successful protocol remains open. We bring to your attention a table by day:

0 DPP - transfer ( cryotransfer)

1DPP- the blastocyte comes out of the shell

2DPP- attachment of blastocytes to the wall of the uterus

3DPP- implantation begins

4DPP- Implantation of the morula into the uterus continues

5DPP- end of implantation

6DPP- the placenta begins to produce hCG

7DPP- an active increase in the level of hCG

8DPP- HCG continues to rise

9DPP-10 DPP- HCG levels reach the minimum of pregnancy tests

About Day 11 ( 11-12 DPP) after the transfer, it is possible to draw conclusions about whether it was successful IVF.

We trust nature

Women re-read tons of literature, trying to find the very ones 5 dpo feeling or 6 dpo sensations, which would indicate implantation and, accordingly, the onset of pregnancy. Actually, to worry about whether it worked out or not, expectant mothers begin to 3 DPO.

This question equally excites girls who have undergone IVF. supposed embryo implantation after IVF They try to catch by minimal changes in the body and well-being. The Internet is full of requests, like " 5 dpo three days», « 4 dpp five days ", « 7 dpo five days with which women look for positive stories.

A bitter disappointment is the absence of even a hint of a second strip on Day 8 or period after embryo transfer. But in fact, the answer to the question of whether why the embryo does not take root, may be an objective situation of natural selection. The unviable fetus was rejected, giving way to healthy offspring.

In fairness, it should be noted that if such rejection is repeated constantly, then this is an occasion for a full medical examination. The reason for the failure of a long-awaited pregnancy may be male infertility.

Implantation is a critical point, because a blastocyte is perceived by a woman's body as a foreign object, due to the presence of male genes in the cell. The speedy and successful introduction into the endometrium and the onset of a normal healthy pregnancy depend on how well the defense mechanisms of this cell work.

It is quite natural that every girl with the onset of a certain age wants to experience the happiness of motherhood. Unfortunately, it is not always possible to get pregnant naturally, which is facilitated by various negative factors.

Fortunately, now you can make your dream come true by using in vitro fertilization. In this case, an egg is placed in the woman's uterus, the fertilization of which was carried out under artificially created conditions.

It is no wonder that such a pregnancy requires supervision by the medical staff. And special attention in this case is paid to control the level of hCG. How does hCG increase after embryo transfer, and what can its indicators indicate?

Chorionic gonadotropin is the most important hormone, the production of which is carried out immediately after the embryo is placed in the uterine cavity. At the same time, at first, it is synthesized by the chorion - a protective shell in which the embryo is located.

At the beginning of the next trimester of pregnancy, the membrane is converted into the placenta, which continues to produce hCG, supporting the life support of the unborn baby. A significant increase in the hormone is observed a couple of weeks after the fertilization of the egg. It was at this time that they began to track the dynamics of hCG after IVF.

HCG levels are monitored throughout pregnancy. This hormone is a marker for early stage identify deviations in the development of the fetus and possible deviations during pregnancy. It is especially important in in vitro fertilization, since in this case the risk of rejection of the fetus by the mother's cells increases significantly.

After embryo transfer, hCG values ​​that exceeded 1000 mU / ml already allow us to examine the fetus in more detail using ultrasound.

Each person is inseparable from chorionic gonadotropin, because in any organism, both in women and in men, it is produced by the pituitary gland. However, its level in the normal state ranges from 5 to 15 mU / ml.

On what day after embryo replanting does the active growth of hCG begin? This process begins on average in 5-6 days. A rapid increase in the level of hCG after IVF occurs from the second week, provided that the artificial insemination procedure was successful. Up to 15 weeks after IVF, hCG during pregnancy continues to grow, and then the increase slows down, resuming only by 22 weeks.

The success of the embryo transfer is judged by the results of a blood test taken from future mother. And compare the results with normal indicators the hCG table helps after the transfer of fertilized eggs by week.

It should be borne in mind that the data of the hCG table after IVF are only an approximate guideline, and small deviations cannot indicate the presence of a pathology.

But maximum control over the development of the fetus allows you to carry out the level of hCG growth by day. For this purpose, women are advised to donate blood every 2-3 days.

The results of the analyzes can be compared with the hCG table after IVF by day.

In the process of in vitro fertilization, four or five embryos are usually placed in the uterine cavity. One or two of them may take root. It is possible that all of them will fully develop. In this case, the extra embryos are removed from the woman's body and frozen. In the future, with an unfavorable course of pregnancy, cryotransfer of already grown embryos can be carried out.

But some women agree to bear several babies at once. And this factor must be taken into account, referring to the hCG indicators on the days after IVF. In multiple pregnancies, normal hCG increases by day after embryo transfer in proportion to the number of fetuses.

Stories with happy endings

Despite the assurances of doctors about the indicativeness of tests for the value of hCG, there are real examples confirming that low hCG after IVF is not always a pathology. This result, rather, is a feature of the body of every woman, so the hCG growth table is not indicative.

The first case occurred with a woman who was planted with two five-day pills. On day 8, the hormone level is 1.32, on 9 DPP it is slightly higher than 5.6, as a result of which the doctor recommended the abolition of hormonal support for pregnancy, considering it failed. Despite this, the woman believed in a miracle and did not refuse to take the drugs prescribed to her.

On day 10, practically nothing has changed, and after evaluating the result of the analysis the next morning, the doctor suspected an ectopic pregnancy, and that further admission medicines will lead to the support of pathological pregnancy.

At 14 and 16 DPP, the hCG results were 74.3 and 132.7, respectively. And on the 18th day, an ultrasound examination was performed, according to the results of which a fetal egg was not found in the uterine cavity.

The next ultrasound was performed on the 22nd day after transplantation. Preliminary hCG indicators gave a result equal to 1152.82. And this norm was finally confirmed by ultrasound, which showed that one fetal egg is in the uterus.

Subsequently, the level of the hormone was within the normal range, and the heartbeat of the embryo was detected at 32 DPP. At the same time, throughout the pregnancy, it was repeatedly observed uterine bleeding, which was caused by taking hormonal drugs.

In another case, a woman was also planted with two five-day babies. She then tracked IVF results by day.

On the 7th day after infusion, the result seemed to be hopeless, since hCG was at the level of 88.6. Two days later, it increased to 412, and the rapid test was reassuring with only a slightly visible second line. HCG on day 14 is 840.5, and on day 17 there is one fetal egg in the uterus, which was confirmed by ultrasound. At 25 DPP, there are already two five-day weeks, and two heartbeats are heard on ultrasound.

You need to use the hCG table after IVF by day, but you should not take these figures as a dogma. It should be borne in mind that norms are calculated differently in each laboratory. In addition, the rate of the hormone in the blood of a woman depends on many factors, including the date elapsed from conception, age, body weight and genetic predisposition. Therefore, it is important to endure all adversity without falling into a panic that can harm the unborn baby.

Bibliography

1. Women's consultation. Management, Editor: Radzinsky V.E. 2009 Publisher: Geotar-Media.
2. Medicines used in obstetrics and gynecology / edited by V.N. Serov, G.T. Dry / 2010, ed. 3, corrected and supplemented - M.: GEOTAR-Media.
3. Emergency care in obstetrics and gynecology: a brief guide. Serov V.N. 2008 Publisher: Geotar-Media.
4. Emergency conditions in obstetrics. Sukhikh V.N., G.T. Sukhikh, I.I. Baranov et al., Publisher: Geotar-Media, 2011.
5. Clinical guidelines. Obstetrics and gynecology. Savelyeva G.M., Serov V.N., Sukhikh G.T. 2009 Publisher: Geotar-Media.
6. Anomalies of labor activity: a guide for physicians. UMO vulture medical education. Podtetenev A.D., Strizhova N.V. 2006 Publisher: MIA.