What is the diffuse changes in the pancreas. Diffuse changes in the structure of the liver: diagnosis, shapes and methods of treatment

02.07.2019 Information

A healthy liver has a homogeneous structure without seals and the presence of deformations in the tissues. But often there may be diffuse changes. They lead to a violation of the homogeneous structure of this organ and the formation of pathologies in tissues.

Consider in more detail what diffuse liver changes, which reasons they provoke and how they are diagnosed.

Diffuse liver changes: concept

Diffuse changes The liver is an increase in the parenchyma of this organ, which is the main functional tissue consisting mainly of hepatocytes. It is important to understand that diffuse changes are not a disease, but only a symptom of some kind of hepatitis, lipomatosis and so on. Therefore, after their diagnosis, additional examination is required. Only it will help to reveal what disease has evolved in humans.

Signs and causes of the disease

Diffuse liver changes may occur for a variety of reasons. Here is the list of the most common of them:

Also provoke such changes can frequent consumption of oily food, long-term treatment with antibacterial drugs or transition to a new diet. It is very dangerous if they arose against the background of hepatitis, cirrhosis or sclerosing cholangitis, as the treatment may not give the desired results.

It is important to consider that with diffuse changes, the work of the organ is maintained, but if they have arisen a long time and has not been treated, there may be heavy liver failure. It is often accompanied by bleeding and intoxication, which has an increasing character.

Signs of diffuse liver changes may not be observed for a long time. But later the patient can celebrate:

  • headaches;
  • nausea;
  • general weakness;
  • increased fatigue;
  • irritability;
  • frequent vomiting;
  • constant change of mood;
  • the taste of bitterness in the mouth.

If such symptoms appear it is very important to consult a doctor and pass the survey.

Diagnosis of the disease

To identify diffuse liver changes, first of all it will be necessary to pass an ultrasound. This body due to its high density and large sizes perfectly reflects sound waves, so it is perfectly scanned during such a survey. In the presence of such changes during the ultrasound, the following will be revealed:

  • inhomogeneous fabric structure;
  • high echo orality of parenchyma;
  • change pattern blood vessels;
  • the presence of sections of increased and reduced echogenicity.

When detecting diffuse liver changes, it is very important to identify the true cause of their occurrence. For this, additional research is appointed:

  • angiography;
  • blood test;
  • histological study of liver tissue;
  • magnetic resonance imaging.

Often it may be necessary to examine the digestive organs. Based on the results obtained, the doctor appoints treatment.

Treatment of the disease

The main treatment of diffuse liver changes is reduced to the observance of a strict diet. So, along with them, lipomatosis is diagnosed, bold dishes will be eliminated, sugar diabetes It will take to limit the consumption of carbohydrates, and during cirrhosis and hepatitis cannot be included in the diet smoked and high-calorie food. In any case, the diet for the patient is selected individually to the doctor.

Often when passing ultrasound internal organslocated in abdominal cavityThe doctor makes a diagnosis of diffuse liver changes. The name sounds quite seriously and inspires concerns. Nevertheless, it does not indicate any disease, but indicates that the liver parenchyma is increased, which is the main functional tissue of this organ consisting of hepatocytes.

This violation is often found and is found even to young children. Although it is not a disease, however, indicates violations of the liver function. Such a violation is sclerotic or hypertrophic. It can be dystrophic and swelling. But always means that there are changes in the liver tissue and additional examination should be carried out.

It should be noted that such changes usually do not have any manifestations. Sometimes they can remind themselves to the rustic pain in the right hypochondrium. Might be felt gravity, discomfort in this area. Sometimes the pain can give to the area of \u200b\u200bthe right forearm, there is a yellowing of the scool eyes, the skin around them. Let's get more about the diffuse changes in the liver parenchyma, the treatment of this state will find out.

Why do diffuse changes occur?

Any negative impact on the liver, starting the disease of this organ always changes the diffuse tissue. Such a change can cause bad habits, in particular, alcohol, medications, bad nutrition with the predominance of greasy and non-human products. And, of course, malicious viruses, bacteria and even lead to diffuse changes. hereditary pathology.

Therefore, if you smoke, love to drink beer or something to be stronger if you are a supporter alone or suffer from obesity - an impartial ultrasound will definitely reveal this pathology.

It should be noted that quite often signs of diffuse liver changes are found in conjunction with pancreatic pathology. This is because the pancreas and liver are associated with ducts, as both of these organs are involved in processing, digesting food.

The most dangerous disease that causes diffuse liver change is hemochromatosis. He causes metabolic lesions This organ. Defeats can be autoimmune, medicinal origin. These include such dangerous diseaselike hepatitis, cirrhosis, as well as sclerosing cholangitis.

Treatment

You do not need to change the changes. An additional examination should be conducted to identify the reason that caused this pathology and take measures to restore the health of the liver. Depending on the reason for the detected reason, the methods of therapy are selected.

In the event that the changes were caused by alcohol, incorrect power, should take measures to eliminate these negative factors. Exclude alcohol from the diet, observe a diet with a minimum content of fats. It is recommended to take antiprotectors that contribute to the restoration of the liver due to the activation of healthy hypotocytes.

If the cause of changes is viral infection, it is necessary to take measures to appropriate treatment using antiviral medicines. It is also necessary to start adherence to the diet. But, of course, the treatment must appoint a doctor.

In any case, if diffuse liver changes were detected on the ultrasound, you will be sent to an additional examination. It will be necessary to pass the blood test, including perhaps on the monarchors. It will be necessary to pass KTM, magnetic resonance imaging or angiography. In addition, histological research is possible.

Only after receiving a full picture of your condition, the doctor will be able to identify the disease and make a diagnosis. After that will be appointed necessary treatment.

Popular treatment

Folk Medicine When detecting diffuse changes in the liver parenchyma, it recommends that this organ is cleared with natural, plant products. Of course, this procedure can be carried out only with the permission of the attending physician to prevent possible complications.

So, for the procedure, it should be mixed in a suitable glassware of 3 cups of washed whole oats, 2 tbsp. l. Dry mint leaves, 3 tbsp. l. Dried or fresh birch kidneys. Now mix everything thoroughly, grind. Follow 3 liters of pure water. Leave this way to stand. Then everyone boost, reduce the boiling point to a minimum. Tomite so 15-20 minutes.

Now, without removing from the stove, add to the brave of 3 tbsp. l. Crushed grass Audit, still pour 2 tbsp. l. corn stilts. Continue to cook for another 15 minutes. Then remove the dishes from the stove, warming up, leave the decoction for another 1 hour.

Prepare a richness of the infusion in advance. To do this, grind 1 cup of rosehip, negotiate in 1 liter of boiling water 10 minutes. After that, all break into the thermos, leave for a day.

Both ready-made bravery rescue, mix, break into the clean bank, which stored in the cold. Drink on an incomplete glass (150 ml.) Up to 4-5 times per day. Be sure to take a mixture of rags before eating for 10 days.

In conclusion, it should be noted that diffuse changes in the liver can be detected from most adults. It is necessary to collect the results of the survey, after which turn to the hepatologist. The specialist will appoint a detailed survey of the liver, will detect the problem and prescribe the necessary treatment. Be healthy!

Liver B. human organism Plays the role of a kind of filter through which blood passes and cleaned from toxins. In nature, this iron is designed so that hepatic cells are deprived of nerve endings. That is why the liver fabric itself cannot hurt.

Most diseases in the liver flows asymptomatic. This happens while the size of the liver does not become highly enlarged. The enlarged body stretches the capsule that covers the liver, affecting the numerous nerve endings located in it.

Then a person begins to experience pain in the liver area (), but years can take it. For a long time, you can not know that the liver suffers and requires help. The compensatory abilities of the organ are huge. Often, pathological changes are detected by chance during the ultrasound study of other organs.

Diffuse liver changes, what is it?

The concept of "diffuse changes" is not a diagnosis and does not disclose the essence of the process developing in the authority. This term is used by diagnostic devices during ultrasound diagnostics.

What it is? Diffuse liver changes are the change in the structure of the tissue, which is common to the entire organ relatively uniformly. So many diseases can appear. A doctor who conducts an ultrasound - study sees these changes in the form of an increase or decrease in the echogenicity of hepatic tissue.

The conclusion made after the ultrasound is the starting point for additional methods Studies of the liver and identifying a particular disease.

The reason for the appearance of diffuse changes in the liver may be diseases that affect the hepatic parenchyma. These may be inflammatory diseases of the liver of viral nature (hepatitis), fat rebirth of hepatocytes due to alcohol intoxication, with poisoning, with long-term reception of potent drugs.

The structure of the liver can be violated due to autoimmune diseases, with cirrhosis of the liver of any origin, infiltrating tumors.

Also, changes in the liver tissue can occur when the diet is non-compliance and with excessive consumption of oily, fried food. Less often changes are congenital.

Signs of diffuse liver changes

As mentioned above, liver disease can be asymptomatic. The liver can serve signs, but rarely are regarded properly.

Signs of diffuse changes in the liver clinically can manifest as heaviness in the right hypochondrium, headache, Fast fatigue, stool disorders, loss of appetite, bitter taste in the mouth, the smell of mouth.

The appearance also may indicate problems in the liver: the skin becomes an unhealthy color with a yellow or brown tint, in some cases there is a loss of body weight.

Diffuse liver changes in ultrasound diagnostics


One of the most accessible and non-invasive methods of liver survey is considered ultrasound. The ultrasound apparatus is available in each treatment and diagnostic institution.

It is good method and the fact that it does not require long-term preparation. The patient just sufficiently stick to the diet a couple of days before the study aimed at reducing gas formation in the intestine. Gas bubbles distort the real picture and interfere with the ferris of organs.

The study should be conducted by a doctor who has an education and certificate for a given narrow specialty.

Consider what diffuse changes can detect a doctor when conducting a liver ultrasound.

Healthy liver

If the liver of a person is absolutely healthy, then with ultrasound diagnostics it has normal sizes, smooth edges. The echogenicity of the liver is normal to be weak intensity. In the location of the vessels, echogenicity is reduced.

The structure should be homogeneous throughout the organ with a challenge characteristic of the liver.

Changes in fat health hepatosis

Fat hepatosis is called a condition in which fat is postponed in the cytoplasm of hepatocytes. This is a very frequent phenomenon with alcohol intoxication, obesity, diabetes mellitus.

Diffuse fat changes in hepatic cells on ultrasound are recorded in the form of amplification of the echo signal throughout the area of \u200b\u200bthe organ. The liver is enlarged and has rounded edges. Sometimes diffuse liver changes are combined with changes in the pancreas and spleen.

If the fat hepatosis is left without treatment, then in the future it can grow into cirrhosis of the liver.


With cirrhosis, the liver cloth germs connective tissuewhich forms false liver lobby. The liver becomes dense, with an uneven surface, hepatocytes different sizes - Part compensatory increased, part in the state of atrophy. On the site of the dead hepatocytes grows a rough connective tissue.

The ultrasound is revealed as follows:

  1. There is an increase in echoes. The liver fabric has a mosaic look.
  2. The sizes of the body are increased (in the last stage of the disease, on the contrary, are reduced).
  3. The surface of the liver is buggy due to the formation of nodes.
  4. Vascular drawing changes: a gorgeous vein with a thickened wall, numerous collaterals are found.

Uz-signs of hepatitis

Hepatitis is inflammatory changes in the liver caused by viruses, alcohol, toxins, etc. Hepatitis can be acute and chronic. Uz-signs in hepatitis are nonspecific. Diagnosis The doctor has the right only after the relevant tests.

With sharp i. chronic hepatitis There is a strengthening of echoes. The liver is enlarged. Parenchima can be homogeneous or with heterogeneity foci.

Due to the fact that it is difficult to put an accurate diagnosis on the results of a ultrasound study, the doctor who has conducted a study indicates only the nature of the changes seen: diffuse or focical changes Hepatic fabric.

In the future, the patient must pass more detailed diagnosis to clarify the diagnosis.


Before thinking about how to treat changes in the liver tissue, the doctor should deal with which the disease led to these changes. For this, it must conduct additional analyzes and research. Only after setting clinical diagnosis, Treatment is assigned.

Will it successful treatmentdepends on the nature of the disease and the degree of change in the liver tissue. Moderate diffuse changes in the hepatic fabric are detected in a large number of people. More often their appearance is associated with incorrect power, reception alcoholic beverages, smoking, bad ecology.

In most cases, diffuse changes are good to treat. For example, diffuse changes in liver parenchyma flowing by type fat hepatoma can be eliminated.

It is enough just to completely exclude the reason leading to the obesity of hepatocytes. Studies have shown that hepatocyte fatty dystrophy caused by alcohol intoxication In the exclusion of provoking factor is capable of reverse development. After 6 months, hepatocytes containing fat drops in their cytoplasm become absolutely healthy.

This applies not only to alcohol, but obesity of the liver due to improper nutrition. It is necessary to stick to the diet so that the fat ceases to be deposited into hepatic cells.

There are situations where the patient has for a long time to take complex drugs that have toxic effects on hepatocytes. Often, this is observed in the treatment of severe diseases requiring long-term therapy, for example, with tuberculosis or tumor processes.

In this case, the appearance of changes in the hepatic tissue is inevitable. To prevent the lesion of the liver, the doctor prescribes the preparations of hepatoprotective action. The drugs of this group are capable of forming a protective shell on the surface of the hepatic cell, protecting it from toxic lesion.

Also effective treatment with viral diseases, It suffices to undergo an antiviral therapy. It is important to consult a doctor when the changes in the tissue have not yet managed to go far, and the structure of the liver has not been deformed.

It is clear that with cirrhosis or diffuse tumor process, it is quite difficult and almost impossible to return the liver for the same structure. But with a timely visit to the doctor, you can suspend the pathological process, and save the life to the patient.

Do not be afraid, seeing the phrase "diffuse changes" in conclusion. Sometimes it is even for the benefit of the patient. So, when detecting weakly or moderately pronounced changes, a chance appears on full cure and preventing the development of severe liver diseases with a pronounced violation of the structure and function of the organ.

Seeing the recording "diffuse liver changes" in its history, the sick person is immediately frightened, because it does not imagine what it is and what can be threatened.

In fact, if we are talking about the diffuse changes in the liver parenchyma, this does not indicate the presence of some particular disease.

What are diffuse changes?

First you need to find out what diffuse liver changes in the patient of a person, what are their signs than they are caused and how to conduct treatment.

Parenchima is what the liver consists of, its main fabric. Parenchima is permeated with a variety of blood capillaries.

It goes the bile vessels that deliver bile from the liver into the gallbladder.

It is possible to determine what happened to something bad can be fixed by the echo drive of diffuse liver changes.

Diffusion is the interpenetration of various particles in the event of their interaction among themselves. Diffusion occurs constantly, including in the human body.

However, on the influence of various negative factors, diffuse changes of the liver parenchyma occur when hepatocytes begin to work incorrectly, and the body begins to build connective and adipose tissue.

Healthy cells are gradually dying, and the structure of the hepatic tissue takes the heterogeneous composition. In this case, they talk about diffuse changes in the liver tissue.

You can fix this process on ultrasound. In the normal state, the parenchyma has a weakly-how.

In the event that the echographic signs of diffuse liver changes were established, the doctor will not immediately appoint medication.

It is necessary to conduct a further examination of the bubble echostructure, biliary ducts and other digestive organsTo understand how touched by inflammatory processes.

Diffuse changes in liver and pancreas can be minor and expressed.

In the latter case, there is a strong lesion of the liver and replacing healthy hepatocytes for fatty or connective tissue.

If ultrasound exam There is an inhomogeneity of the composition of the parenchyma, then they are talking about diffuse focal changes in the liver.

Moderate diffuse liver changes are often after transferred acute respiratory viral or bacterial disease.

Therefore, the attending physician always asks the patient about the diseases transferred to them.

Signs and root causes of diffuse changes

Quite often the situation occurs when a person does not feel any signs of diffuse changes - the manifestation of the disease completely "lubricated".

However, the improper work of the body during liver failure may be accompanied by such signs as:

  • feeling of gravity and nausea after making food;
  • visible to the naked eye growth of liver in size;
  • the constant unpleasant "metallic" taste in the mouth, especially strong in the morning;
  • urine becomes dark color, feces, on the contrary, discolored;
  • unworked skin rashes, itching;
  • weakness, irritability, dizziness, general state ailment;
  • taking the skin of the yellow color, can even get tongue.

The main symptom that the person's diffuse changes in the liver parenchyma occur are sharply pronounced pain in the right offense.

These formidable signs are a reason for immediate visit to the doctor who will appoint the necessary research and surrender.

Diffuse changes in the structure of the liver may indicate:

Thus, hesitate with treatment and think that "everything in itself will disperse", in no case cannot be. The reasons that lead to diffuse changes are generally known to everyone.

  • incorrect diet (oily, salt, sharp food);
  • abuse of alcoholic beverages;
  • existence of excess weight;
  • sugar diabetes 2 type;
  • glice invasions;
  • disorders of the hormonal background of the body, leading to the wrong exchange of substances in it;
  • thyroid dysfunction;
  • permanent reception drugs (antibiotics).

The most common cause of diffuse changes in the liver and pancreatic parenchyma is drunkenness.

With normal operation, a person liver, this unique biochemical laboratory, can neutralize almost all toxins entering the body in poisoning, drug use and smoking.

However, in cases where the "shock" dose of poisoning substances falls into the body, it does not cope with their work, especially if the toxins come regularly, for several months and even years.

In addition to alcoholic beverages, the cause of diffuse changes in the liver and pancreas can be the so-called energy.

They are even faster than vodka lead to dysfunction of internal organs due to the huge number of poisoning substances.

Even the use of energy 1 time a week can lead to failures in this body.

The unlimited desire to lose weight, the sample of a variety of different, often mutually exclusive diets is the second in frequency of the cause of hepatic diseases.

Long periods of starvation, formulation of enema, the reception of diuretic teas lead to the rebirth of hepacitis.

At the same time, people seem to be trying to eat right, with surprise there are signs of diffuse changes.

Hepatosis and their diagnosis

All these negative factors are the cause of failures in the work of hepatocytes. They are fixed so-called dystrophic changes that lead to the replacement of healthy tissues.

For fatty infiltration, first sections, and then, with neglected diseases, almost the entire parenchyma is replaced by a tide with a fatty type.

At the same time, doctors say that the patient has diffuse liver changes by type of hepatosis.

Hepatosis is the general name of liver diseases, which are characterized by the fact that its healthy tissue is replaced with fatty and connective.


At first, it can still replenish the death of healthy cells, but then, due to excess toxins entering the body, the fat cells are beginning to penetrate into the liver, which it could not destroy.

And now they are becoming more than healthy, hepatocytes are dying, the liver becomes more due to the growth of fat cells and begins to work with failures. Increased cells can be reborn into malignant.

If the hepatosis is not treated, then in the launched state, the disease can go to the next stage - fibrosis, and behind it in cirrhosis.

The most common are diffuse liver changes by the type of steatosis. Steatosis is a subspecies of hepatosis, characteristic of the fact that the parenchyma is replaced precisely fat, and not a connecting tissue.

Steatosis is diagnosed if more than 10% of the healthy liver tissue turned into a fat.

Diffuse steatosis is considered a cunning disease - for a very long time he does not show itself, a person does not feel any signs of illness.

In this case, the liver gradually changes its structure, fat deposits in it becomes more and more.

Diffuse liver changes in body hepatosis can be combined with other diseases of the digestive system.

Therefore, a hepatologist or a gastroenterologist when applying to a patient with signs indicating hepatic failure, appoints the following diagnostic measures:

  • general, biochemical and serological analysis of blood, urine and feces, as well as analysis on monackers (if necessary);
  • Ultrasound diagnosis of liver and other internal organs;
  • puncture biopsy of the liver to find out the degree of destruction of this organ with fat cells;
  • x-ray studies of the liver and, if necessary, gallbladder;
  • computer and magnetic resonance tomography;
  • angiography.

If necessary, the doctor may ask to make any other analyzes or surveys.

It is necessary to be ready for this, because diseases of this kind are very cunning, and to diagnose them is not so easy.


Treatment of the problem

Given the above, the answer to the question - how to treat diffuse liver changes will be necessary to formulate the right diagnosis, because diffuse changes are not an independent illness, it is only a sign of numerous diseases that can be diagnosed subsequently in the patient.

If a small section of the liver is struck by fatty deposits, then the forecast is usually favorable.

Treatment of diffuse changes, in case they are caused by a glitstic invasion, is to appoint appropriate anthelmintics.

If the cause of liver failure was viral or bacterial infectionThe doctor will appoint antiviral medicines or antibiotics as treatment as treatment.

In addition, it is possible to take hepaprotectors - drugs that contain the necessary liver minerals to help it with normal operation.

Treatment of steatosis most often consists in taking substances that prevent the deposition of fatty compounds in the parenchyma.

In addition to them, the doctor usually prescribes the following drugs for reception:

  • b vitamins B;
  • lipo and folic acid;
  • lipamide and methionine;
  • various hepaprotectors ("Esssential Forte", "Carsil", "Hepatral");
  • glybutid, which stimulates the process of synthesis of glycogen.

Sometimes treatment includes steroid preparations, helping to normalize the general hormonal background of the body.

Since usually the cause of hepatosis is the unlimited use of alcohol, adherence to the diet with diffuse liver change, proper nutrition And compliance with the normal lifestyle is considered the main key to the recovery of a sick person.

If a diffuse change in the liver structure is diagnosed, it is strictly prohibited:

  • smoking, drink alcohol-containing, carbonated and energy drinks;
  • there is fried, oily, sharp and salty food;
  • consume seasonings, marinades, spices;
  • there are fresh pastries, confectionery with cream, any chocolate;
  • there are vegetables S. large content Fiber - radishes, sorrel, rhubarb.

From how much patients stick proper treatment, which necessarily includes, with all diseases of the gastrointestinal tract, diet, depends, whether the forecast of the disease will be favorable.

Since the liver has huge reserves of self-healing, moderate changes in parenchyma are adjusted by a special diet and in the right way Life.

With hepatic insufficiency, as dietary treatment, the so-called table No. 5P is prescribed - in the acute course of the disease, and table number 5 at the stage of recovery.

When diagnosing minor deviations in the liver, treatment may consist, including in the reception of the funds of traditional medicine.

Ginger root helps well. It needs to be crushed and take on ½ tsp. 3 times a day for 2 weeks.