According to statistics, about 20% of Russians are faced with the problem of osteoporosis and other diseases associated with calcium deficiency in the bones. On the market you can find a lot of drugs and dietary supplements aimed at restoring calcium and phosphorus deficiency in bones. The task of pharmacists is to make sure that calcium is not only supplied to the body, but also remains there, re-forming a strong skeleton.
The drug "Osteogenon" is aimed at regulation within the bone tissue metabolic processes, the violation of which is the main cause of the development of osteoporosis. The manufacturer of the drug is French pharmaceutical company Pierre Fabre, which has proven itself in the Russian pharmaceutical market.
The medicine helps to increase bone density, which prevents the risk of fractures. The release form of the drug is tablets. Coated, they are manufactured in such a way as to ensure the passage of the tablet through the negative factors of the acidic environment of the stomach and to ensure maximum absorption. active ingredients intestines.
There is no clear indication in the instructions regarding the drug - to take before or after meals. However, the presence of substances in the composition that can irritate the walls of the stomach makes it reasonable to take the drug after meals at regular intervals.
In addition, it is indicated that the drug reduces the effectiveness of iron preparations and antibiotics of the tetracycline group, therefore, if there are any for admission, the difference between the use should be on average 4 hours. This approach will avoid conflict between drugs and ensure full interaction.
The preparation contains calcium hydroxyopatite. This shape allows for better absorption by the walls of the gastrointestinal tract. Calcium is released gradually, which in combination with phosphorus avoids the peak of hypercalcemia.
The presence of phosphorus contributes to the fixation of calcium in the bone tissue and prevents the kidneys from excreting it. Ossein is a regulator of bone remodeling processes, which promote the formation of new structures and prevent destructive processes inside tissues. The drug suppresses the action of hormones, due to which calcium is washed out faster, thus allowing the accumulation of a margin of safety.
The drug Osteogenon for fractures promotes early healing and bone healing, even in such difficult cases as comminuted fractures of the ankle, femoral neck and other injuries that normally require large gap time to heal. When taking the drug, even patients with the Elizarov apparatus note an increase in the dynamics of regenerative processes.
The drug is prescribed for osteoporosis for older people and even for pregnant women, if there is a need for this, confirmed by test results. When prescribing the drug, the patient undertakes to undergo regular blood and urine sampling to detect excess calcium.
For treatment or prevention, patients often ask for a cheaper prescription. In pharmacy chains, the cost can vary significantly, depending on the policy of the owner and the region.
I must say that there is no preparation completely corresponding to the action and effectiveness of Osteogenon. There are analogues that come close enough to this. Compared to Osteogen, the results are as follows:
Russian drugs that are used in similar cases, but are not drugs:
The drugs have different dosages of active substances and are aimed at solving similar problems. However, if necessary, only a doctor, but not a pharmacist, can select an analogue for a specific case. Of course, if there is a problem, the patient cannot determine the drug himself; it is required to consult with the attending physician.
The instructions indicate that the use of the drug is possible from the age of 18. In this case, the doctor must take into account the existing level of calcium in the body, since an overestimated indicator in this case is less desirable than a deficiency.
You can find information that in Europe Osteogenon is prescribed to babies in small doses, but in Russia this practice is only under the responsibility of a specialist. It is used most often for joint dysplasia.
Calcium supplements require very careful use when it comes to children. An excess of calcium in the child's body can provoke early ossification of the bone areas responsible for growth, stopping them in development, which in the future can cause the development of pathologies. So the early ossification of the seams of the child's skull leads to compression of the brain, which provokes headaches and problems in various sensory systems.
Result: positive feedback
13 +
Benefits: Very effective, stops bone breakdown and repairs, quickly relieves osteoporosis
Disadvantages: Extremely expensive, uneconomical
At first, the price of Osteogenon scared me away - is it a joke, a package for 800 rubles is enough for only 10 days! But having tried other calcium preparations, I had to return to the idea of using this remedy - they turned out to be ineffective. Osteogenon turned out to be amazingly good - in two weeks, my DPID (bone destruction indicator) dropped from 7.2 nmol to 6.8 nmol. It inspired me a lot - finally, there was a real chance to escape from osteoporosis. I will not hide that I had to spend a lot of money on Osteognenon, but the result of the treatment cannot fail to impress them. In two months, my tests almost returned to normal - this is for me, a person with a progressive form of the disease! Judging by the urine tests, calcium has ceased to be flushed out of the body - a sure sign that the mineral is not only well absorbed by the body, but also “embedded” into the bone, turning it from a kind of porous sponge into a normal one. After 4 months I underwent DEXA (X-ray type examination, but more effective), and I was glad to know that the process of destruction of my beloved bones has been stopped! Now from time to time, in courses I take the drug - depending on the tests, and so far everything is fine - no "news" has been received from osteoporosis.
Result: positive feedback
Pregnant and effective
Benefits: Safe for pregnant women, fast and strong action
Disadvantages: Very expensive, uncontrolled use can lead to kidney stones
Osteogenon justifies its price by the fact that it can be used by pregnant women. By the second trimester, I was exhausted due to periodontitis and bleeding gums, and the reason for these troubles was not reduced immunity, as I thought, but a very serious mineral deficiency. I passed the tests - my heart fell, the doctor generally said that soon my teeth would begin to crumble. I prescribed Osteogenon, saying that if I do not want to lose my teeth, I will have to spend money. I spent it - which I do not regret. I had been drinking for a month, I completely forgot about problems with the gums - even there was no trace of swelling, not to mention bleeding and pain. At the same time, the drug does not cause harm at all - I felt great, even better than before. But there is one caveat - nothing can be taken uncontrollably, especially calcium preparations. Be sure to periodically get tested for total calcium in order to understand when it is worth stopping taking Osteogenon - otherwise, excess calcium will cause kidney stones.
Result: positive feedback
Helped me and my son
Benefits: Replenishes the supply of minerals, helps very quickly, heals fractures, strengthens bones, nails, hair
Disadvantages: Price bites
I used Osteogenon myself and gave it to my son. In the first case, the problem was in a nightmare that began during lactation - my hair was falling out, my nails were breaking, and, I'm not afraid of this word, my bones creaked. A typical picture for mothers - all minerals-vitamins from the body go into milk, and you suffer from their deficiency. The drug solved this situation very quickly and easily - a month and a half and zero problems. Hair stopped falling out altogether, the nails became noticeably thicker, and most importantly, the creak in the joints and some kind of stiffness disappeared, because of which I used to feel not a young woman, but a grandmother. The second case is connected with the fact that at the age of 12 my son began to grow sharply upward. Poor bones did not agree with such a pace - they became thin, fragile. Five fractures in six months - this is the result. And Osteogenon helped from two sides at once - it strengthened the bones as a whole, thanks to which the fractures were forgotten, and allowed the existing ones to heal quickly. I am delighted with the funds, albeit expensive, but the effect is gorgeous.
Result: positive feedback
Complex and powerful remedy
Benefits: Contains substances that contribute to the complete absorption of calcium, effective, quickly helps, does no harm
Disadvantages: Expensive, seldom sold where
Osteogenon contains not only calcium - it also contains collagen, phosphorus, and magnesium. Thanks to this, calcium itself is completely absorbed from the drug (and not by 30-40 percent, as from drugs like Calcium d3 Nycomed), and the effect of the drug is simply phenomenal. I broke my leg in two places and the fractures were very serious. Healing proceeded terribly slowly - it was predicted that I would have to lie in bed for six months without movement. It's good that there is an Internet in the world - there I learned about this drug. Doctors do not prescribe it - it seems to me, because of the high price. But Osteogenon is definitely worth paying for, and I would give even more money for such an effect. You should have seen the doctor's face when he was examining another picture - quite recently, instead of a bone, I had only "fragments" there, but here - a completely opposite picture, healing is in full swing. In the end, the drug put me on my feet in 3 months - not weak, right? And after this time I could already get up and did not feel much discomfort, except perhaps the stiffness, which I managed to eliminate with the help of physiotherapy and exercises.
Osteogenon is a drug designed to improve metabolic processes in bone and cartilage tissues. It can be assigned only after advanced diagnostics. It is very important to adhere to the instructions for use in order to avoid side effects.
The unique components in the composition of the drug help to increase bone density, which has a beneficial effect on the prevention of fractures. Thanks to a special membrane, the active ingredients are almost completely absorbed by the stomach.
Osteogenon - tablets designed to normalize calcium-phosphorus metabolism. The active ingredient in the capsules is an ossein-hydroxyapatite compound. The main effect of the drug is aimed at accelerating the production of osteoblasts, which reduce the activity of osteoclasts.
By taking this medication regularly, you will be able to speed up bone regeneration by slowing down the destruction process.
Each tablet of this drug contains a certain amount of calcium hydroxyapatite. This component is rapidly absorbed into gastrointestinal tract: Calcium ions, which occur during a chemical reaction, slow down the onset of symptoms of hypercalcemia.
Because of high concentration calcium in the blood slows down the synthesis of parathyroid hormone, thereby stopping the degenerative processes in the bone tissue.
Phosphorus, which is also very much in the composition, has a general strengthening effect for bones. It enters into a chemical reaction with hydroxyapatite, due to which the crystallization process takes place. Calcium ions take part in the same reaction, which prevent the release of necessary components from the body through the kidneys.
Additionally, each capsule contains a certain amount of pure ossein. This substance is a scleroprotein protein that restores the natural structure of bone tissue.
Osteogenon is a medicine designed to normalize the structure of bone tissue. Most often it is prescribed in the following cases:
It is very simple to use Osteogenon, it is suitable for oral administration... The tablet should be swallowed whole without chewing. They need to be written down with a small amount of pure water, food intake does not affect the effectiveness and safety of the drug. The size of the active substance and the duration of such therapy are selected individually, depending on individual indications.
You can take Osteogenon according to the following scheme:
It should be borne in mind that during therapy with Osteogenon it is necessary to be under the comprehensive supervision of a physician.
It is necessary to constantly monitor the level of calcium in the blood and urine in order to prevent the development of hypercalcemia.
Osteogenon is a fairly safe drug that rarely leads to negative consequences. In order to prevent the development of complications, it is strictly forbidden to take the drug if there are contraindications. These include:
At correct application Osteogenon rarely causes side effects. If you do not follow the rules of the instructions for use, you risk facing serious consequences. Most often, the patient complains of the following consequences:
There is no exact data on overdose. If you take too many capsules, you need to induce vomiting. If this fails, drink as much pure water as possible to reduce the concentration of active substances in the blood.
If you feel unwell, symptomatic therapy is performed. See a doctor if necessary.
Osteogenon is a safe drug for pregnant and lactating women. However, before starting such therapy, it is imperative to consult with a qualified attending physician.
It is not recommended to take Osteogenon and antibiotics or iron preparations at the same time - this medicine significantly inhibits the absorption of nutrients. It is necessary to create an interval of at least 4 hours between doses.
It is very important to constantly monitor the level of calcium in the blood if Osteogenon is used together with vitamin D or thiazide diuretics. There is a risk of hypercalcemia due to the increased rate of resorption of this chemical.
The drug is absolutely safe for people with increased blood pressure, it contains only a small amount of sodium chloride. If the patient has a tendency to form stones in bladder, it is necessary to constantly change the dosage regimen of the drug.
Osteogenon Is a new generation drug that serves to regulate homeostasis, enrich the mineral composition of the bone, improve its quality characteristics, stimulate bone formation, and accelerate fracture healing. On the composition, mechanism of action and application rules medicinal product Osteogenon will tell you in detail the instructions for use.
Most fractures are associated with osteoporosis. It is this systemic skeletal disease that is characterized by a decrease in bone mass and density, increased fragility, deformation of bone tissue and an increased tendency to pathological and traumatic fractures. There are many factors influencing the development of osteoporosis, but the main role is played by imbalance in the processes of bone remodeling. Mineral metabolism, the absence in the body of a deficiency of calcium, phosphorus and other components important for the synthesis of bone tissue is of decisive importance for ensuring the preservation and renewal of the skeleton. To combat the problem of insufficient bone mineralization, drugs from the group of correctors of tissue metabolism - cartilaginous and bone are called upon.
The therapeutic effect of Osteogenon is due to the unique complex composition containing organic components of the bone matrix and inorganic substances present in physiologically balanced, optimal proportions. Together, they increase mineral density and improve bone structure. Bone is a natural reservoir of various trace elements and constantly needs to be replenished, primarily calcium and phosphates.
Without a sufficient amount of these active substances involved in many chemical processes in the body, it is impossible to maintain a normal skeletal balance. The restructuring and renewal of bones occurs constantly, in accordance with a given cycle and with the participation of special cells - osteoblasts and osteoclasts. But, under the influence of various negative factors - age-related changes, alimentary calcium deficiency, insufficient or excessive physical activity, diseases endocrine system, rheumatic or other concomitant pathologies, resorption processes begin to prevail over the formation of a new bone matrix and its replacement of the old one.
Osteogenon helps the body restore a disturbed balance.
The effect is achieved by the combined action of the compound active components of the drug, as follows:
Holder registration certificate Osteogenon is a private French pharmaceutical company Pierre Fabre Medicament. Manufacturer - Pierre Fabre group (In Russia, the company operates through its permanent representative office - Pierre Fabre LLC). Ossein-hydroxyapatite complex is available in dosage dosage form targeting internal use through the mouth. These are pale yellow tablets with a protective enteric film coating, an oblong, convex shape on both sides. They are packaged in a 10-cell plastic blister. 4 such blister packs and instructions are included in individual cardboard boxes.
The total dosage of active compounds Osteogenon is 830 mg (in terms of dry substance), of which:
The composition of the Osteogenon tablets also includes a number of additional ingredients, these are:
After oral administration, Osteogenon enters the intestines. The complex is characterized by slow dissolution, long-term absorption, occurs throughout the digestive tract, incl. in the distal part of the intestine.
Due to the slow release of active components, the development of hypercalcemia syndrome is blocked, which increases the safety of the drug with its repeated use and is a significant advantage over conventional calcium supplements. For the manufacture of the ossein-hydroxyapatite complex, a natural highly purified raw material is used - an extract from animal tissues.
Therapy with Osteogenon allows you to achieve the following positive effects:
The studies carried out and the meta-analysis of the results obtained allow us to declare a greater clinical efficacy of the ossein-hydroxyapatite complex Osteogenon in comparison with the therapeutic effect of calcium carbonate preparations etc.
These data correspond to the real reviews left by patients on specialized forums for fractures and answer the question of whether Osteogenon is effective or not.
In addition to a significant (5.5% percentage) increase in mineral density and an improvement in the qualitative composition of bone tissue, a decrease in the risk of fractures, the frequency of adverse reactions and symptomatic improvement in the condition of patients in the form of a decrease in back pain were recorded.
When assessing the effect of the complex on the timing of callus formation and the rate of restoration of bone integrity, it was found that Osteogenon reduces the period of complete fusion by several weeks. The drug is effective for a single isolated fracture and large, multiple injuries. The improvement seen in the X-ray examination, which visualizes the structure of the bone, occurs within 2 months after the start of the course.
Osteogenon is used to prevent diseases caused by calcium deficiency, and as a means of additional therapy in combination with other medications.
According to the instructions, Osteogenon is indicated for admission if:
The doctor decides on the advisability of using the Osteogenon complex. The dosage and duration of the course depend on the nature of the damage and the body's need for trace elements and protein organic compounds. With osteoporosis, the course usually lasts at least six months, with a fracture of small severity - 2-3 months. Osteogenon tablets are taken with food, without crushing or chewing, washed down with half a glass of water.
Only very high doses of Osteogenon lead to an overdose - 11 tablets or more, taken within 1 day. Such drug abuse threatens the development of hypercalcemia with all its characteristic features, including the formation of kidney stones and neurological symptoms.
Osteogenon is contraindicated for use in patients with:
Osteogenon is well tolerated. There are only isolated cases of undesirable phenomena, the instructions indicate that with a frequency of less than 1/1000000, the following may develop:
It is not forbidden to combine Osteogenon and alcohol in an adequate amount, because under this condition, it does not affect the action of the drug.
The instruction imposes a prohibition on joint application with thiazide diuretics. Caution should be exercised when taking Osteogenon in combination with cardiac glycosides, bisphosphonates, hormonal agents, iron preparations, strontium or zinc-containing supplements.
Osteogenon is dispensed by prescription. In the absence of exposure to high temperatures (above 30 degrees), tablets are suitable for 4 years. The average cost of a package of 40 tablets is 650 rubles. There are no absolute analogues of Osteogenon (with the same composition and ability to influence the course of tissue mineralization to the same extent). The complex can be replaced with medicines similar in content of active substances. The analogue of Osteogenon in tablets and capsules is:
All drugs belong to the same pharmacological group, but they act by different mechanisms and achieve unequal results. The choice of a suitable analogue should be entrusted to the attending physician.
In this article, you can read the instructions for use medicinal product Osteogenon... The reviews of site visitors - consumers of this medicine, as well as opinions of doctors of specialists on the use of Osteogenon in their practice are presented. A big request is to actively add your reviews about the drug: whether the medicine helped or did not help get rid of the disease, what complications and side effects were observed, which may not have been declared by the manufacturer in the annotation. Analogs of Osteogenon in the presence of available structural analogs. Use for the treatment of osteoporosis and accelerate the healing of bone fractures in adults, children, as well as during pregnancy and lactation. Composition of the preparation.
Osteogenon- a drug that affects bone mineralization (regulator of calcium-phosphorus metabolism).
Osteogenon contains the components necessary for the synthesis of bone tissue and has a double effect on the metabolism of bone tissue: it stimulates osteoblasts and inhibits osteoclasts.
Calcium is contained in the preparation in the form of hydroxyapatite (in a 2: 1 ratio with phosphorus), which contributes to its more complete absorption from the gastrointestinal tract. Inhibits the production of parathyroid hormone and prevents hormone-mediated bone resorption. The delayed release of calcium from hydroxyapatite results in the absence of a peak in hypercalcemia.
Phosphorus, participating in the crystallization of hydroxyapatite, promotes the fixation of calcium in the bone and inhibits its excretion by the kidneys.
Ossein is an organic component of the preparation containing local regulators of bone tissue remodeling (beta-transforming growth factor, insulin-like growth factors 1 and 2, osteocalcin, collagen type 1), which activate the process of bone formation and inhibit bone resorption.
Beta-transforming growth factor stimulates the activity of osteoblasts, increases their number, promotes collagen production, and also inhibits the formation of osteoclast precursors.
Insulin-like growth factors 1 and 2 stimulate collagen and osteocalcin synthesis.
Osteocalcin promotes bone crystallization by binding calcium.
Collagen type 1 is responsible for the formation of the bone matrix.
Composition
Ossein-hydroxyapatite compound + excipients.
Indications
Forms of issue
Film-coated tablets 830 mg.
Instructions for use and dosage regimen
The duration of treatment is determined by the patient's condition.
Side effect
Contraindications
Application during pregnancy and lactation
Osteogenon can be used during pregnancy and during breastfeeding if indicated after consulting a doctor.
Application in children
Osteogenon is contraindicated in childhood.
special instructions
In patients predisposed to urolithiasis, it may be necessary to adjust the dosage regimen of the drug, depending on laboratory parameters.
In patients with impaired renal function, prolonged use of high doses of the drug should be avoided.
The preparation contains only trace amounts of sodium chloride, therefore it is permissible to use Osteogenon in patients with arterial hypertension.
Drug interactions
Osteogenon slows down the absorption of iron preparations, bisphosphonates and antibiotics of the tetracycline group, therefore, when used simultaneously with these drugs, the time interval between taking them should be at least 4 hours.
With the simultaneous use of Osteogenon with vitamin D or thiazide diuretics, the doctor should assess the risk of developing hypercalcemia due to increased calcium resorption.
Analogues of the drug Osteogenon
Structural analogues in active substance the drug Osteogenon does not have. The drug contains a unique active ingredient in its composition.
Analogs on therapeutic effect(drugs for the treatment of osteoporosis):
In the absence of analogues of the drug for the active substance, you can follow the links below to the diseases for which the corresponding drug helps, and see the available analogues for the therapeutic effect.