Thareloit chronic autoimmune honey.
Chronic autoimmune thyroiditis - thyroiditis, usually manifested by goiter and symptoms of hypothyroidism. Significantly increased risk of malignization thyroid gland. The predominant age is 40-50 years. Women are watching 8-10 times more often.
Handbook of Diseases. 2012 .
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Thyroid gland can be subjected to various pathological processes. One of them is inflammation (thyroiditis). To one of the common forms inflammatory process It belongs to autoimmune thyroiditis (AIT). Code of the disease according to the ICD 10 - E06.3.
Ait is chronic inflammation of the thyroid gland of autoimmune genesis. The disease is characterized by destructive processes in follicular gland cells. Diagnose pathology on the basis of the characteristic external view Patient, results of laboratory tests, ultrasound. According to statistics, more than 50% of patients with problems endocrine system Have ait. It can proceed both independently and accompany other diseases. Therapy is aimed at restoring the thyroid function by applying hormonal prepartes.
Ait is a group of diseases having the same nature. The following types of autoimmune thyroiditis are distinguished:
All forms of AIT are developing by phases:
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Criteria for diagnostics AIT:
If even one of the items is missing, the diagnosis will be the nature of the assumption. Each of the items separately is not proof of autoimmune thyroiditis.
To get rid of the cause of AIT (improper work of immunity) is impossible today. Suppression immune system Reduces the protective functions of the body and the person becomes very vulnerable to the attack of viruses and bacteria. Therefore, the main tactics of the treatment of autoimmune thyroiditis is to replenish the lack of thyroxine - hormone, which thyroid gland synthesizes from iodine.
To remove the inflammation of the thyroid and raise the level of lack of hormones, the synthetic thyroxine (levothiroxine, L-thyroxine) is prescribed. It allows you to normalize the hormonal background. During treatment, it is necessary to regularly monitor the level of content. thyreotropic hormone in blood.
If the treatment is carried out correctly, thyroxin does not cause any side effects. But it should be noted that the medicine will have throughout life to support the normal functionality of the thyroid gland.
The increase in antibodies in the body requires the use of NSAIDs:
With a launched ait and a significant increase in the thyroid gland, surgical intervention is carried out. Instead of operation, you can use irradiation of the organ radioactive iodom. The removal of the thyroid glands does not reduce the activity of autoimmune processes and can even trigger diseases of the reproductive system (ovary cyst, mioma of the uterus). In addition, the patient develops steady hypothyroidism. Therefore, operations are assigned in case of extreme need.
Aukimmune thyroiditis (AIT) requires constant medical control. Unfortunately, methods that can completely get rid of the disease does not yet exist. Ait is a risk factor of the development of hypothyroidism. Therefore, it is necessary to regularly check the functionality of the thyroid gland and when changing the hormonal background to carry out substitution therapy.
This video presents a brief information on the diagnosis and treatment of chronic autoimmune thyroiditis:
08.12.2017
Autoimmune thyroiditis (AIT) is included in the registry international Classification Diseases (ICD 10) as an endocrine pathology of the thyroid gland and has code E06.3. Thyroiditis hashimoto, as they often call it lymphocytic an autoimmune disease, refers to chronic pathology inflammatory genes. Often, autoimmune inflammation of the thyroid gland moves into hypothyroidism - a state of particular danger to children.
For the first time, the disease described the Japanese surgeon with the surname of Hashimoto in the early 20th century, and Zob Hashimoto from now on began to have an identical name. What does autoimmune mean? Translated from Latin "Auuto" means "himself." An autoimmune response of the body is due to the aggression of immune cells to its own, in this case, the thymocytes - thyroid cells. The main difference between autoimmune thyroiditis is that the inflammatory process can be launched both in an enlarged and even unchanged gland tissue.
It has been established that in the development of the disease plays an important role of heredity. But so that the disease manifested itself to fully, should be accompanied by adverse predisposing factors:
How autoimmune thyroiditis develops
Ait - the disease is slowly progressive and mostly occurring in people a weak half of humanity. His prevalence in children is equal to a little more than 1% per capita. The fact is that on early stages The clinical picture of the disease may not be exercised in any way, but the symptoms are completely absent. Sometimes there are pain when tamping the thyroid gland. Some patients noted the appearance of articular pains, weakness. Often the first sign of the thyroiditis of autoimmune nature is imperceptible to the external increase in the tissue of the thyroid gland.
Depending on the changes occurring in the organs, the thyroiditis may be euthyroid, hyperthyroid or hypothyroid is the most cunning form of the disease. Each state is characterized by appropriate features. In young people with a healthy strong organism and strong immunity, eutheosis can be diagnosed for a long time - the state when the necessary hormones in the blood is necessary and the optimal amount.
The subclinical picture of the AIT can report changes in the function of the gland not only symptoms, but also laboratory results. There is an increase in the level of thyroxine, and the figures of the thyrotropic hormone are reduced. The hormone-dependent form of Aita - pronounced hypothyroidism and this is the worst, since long-term consequences are possible. Why? The fact is that the hypothyroidism at Aite is the inevitable outcome of the disease in most cases. And many patients are afraid of lifelong reception of hormones, as it is single way out The treatment of AIT with hypothyroidism.
An autoimmune thyroiditis in adults may be the beginning of the eye pathology. Almost all patients appear problems with eyes, the so-called endocrine ophthalmopathy, which can be expressed in bright symptoms:
The diagnosis is established in the presence of an elected history and all necessary research activities:
When Aite is important to protect the body from outbreaks of inflammatory reactions and sluggish chronic processes. If the function of the gland is increased, then soothing drugs are shown, reduced stress levels. In most persons suffering from this pathology, the products of thyroid hormones decrease, therefore, with a tendency to hypothyroidism, replacement hormone therapy and drug reception of L-Troyroxine in doses recommended by the doctor are prescribed as the main treatment.
It is resorted to a surgical method with a fairly extensive growing of gland fabric and in cases where it can put pressure on the respiratory center. Reception of iodine-containing products for the prevention and treatment of hypothyroid form Aita is quite acquitted. The disease occurs with an increase in the function of the thyroid gland requires the exclusion of products rich in iodine, since they will contribute to an even greater increase in the number of thyroid hormones.
When maligning (reincarnation of gland fabric), surgical intervention is prescribed. A favorable effect of both the organism in general and the inflamed thyroid houses are grass, the reception of some vitamins and bodies.
Selenium as an important trace element is needed hardware for its proper functioning. The component can reduce autoimmune attacks on this delicate and susceptible organ. With a lack of selenium in the body, thyroid hormones are not able to fully work, although their development continues. However, the reception of selenium is better to combine with iodine preparations in the absence of disorders of the thyroid function.
Based on use useful products. Leading power principles are based on the restriction of products and dishes that provoke or enhance autoimmune reactions. Aite diet is not a significant factor in curing the ailment, but with the corresponding coordinated diet, it may remove the development of hypothyroidism and improve general state. First of all, it is necessary to achieve the harmonization of the hormonal background.
Each form of AIT requires an individual diet for a patient built, taking into account the recommendations of the nutritionist. The state of the eutheroid does not require any dietary instructions, as they are not justified. So, due to the fact that the main metabolic metabolism in hyperthyroidism is increased, high-calorie food is recommended, providing greater energy consumption. The menu should present a sufficient amount of proteins, fats and vitamins. For patients with elevated gland function, dishes and products that are exciting affecting cardiovascular and nervous Systems. This is coffee, energy, strong tea.
For persons with hypothyroidism, on the contrary, it is important to increase the metabolic level. Fat and carbohydrates are limited, and the amount of protein increases slightly. You need to use easily friendly and useful food.
An autoimmune thyroiditis is a pathology, which is mainly susceptible to the elderly women (45-60 years). The pathology is characterized by the development of a strong inflammatory process in the field of thyroid gland. It arises due to serious failures in the functioning of the immune system, as a result of which it begins to destroy the cells of the pin.
The susceptibility of pathology is precisely the elderly women due to X-chromosomal impaired and the negative effect of estrogen hormones on cells forming a lymphoid system. Sometimes the disease can develop, both in young people and young children. In some cases, pathology is also found in pregnant women.
What could cause AIT, and is it possible to recognize it yourself? Let's try to figure it out.
An autoimmune thyroiditis is inflammation flowing in the tissues of the thyroid gland, the main cause of which is a serious failure in the immune system. On his background, the body begins to produce anomalous large amount of antibodies that gradually destroy healthy thyroid cells. Pathology develops in women almost 8 times more often than men.
Thyroidita Hashimoto (pathology received its name in honor of the doctor who was the first to describe its symptoms) develops for a number of reasons. A primary role in this matter is given:
However, it is not necessary to panic - autoimmune thyroiditis is a reversible pathological process, and the patient has every chance to establish the work of the thyroid gland. To do this, it is necessary to ensure the reduction of loads on its cells, which will help reduce the level of antibodies in the patient's blood. For this reason, very important is timely diagnosis Diseases.
An autoimmune thyroiditis has its own classification according to which it happens:
All types of AIT, besides the first, manifest themselves among the same symptoms. The initial stage of the development of the disease is characterized by the occurrence of thyrotoxicosis, which, in untimely diagnosis and treatment, can go into hypothyroidism.
If the disease was not detected in a timely manner, or for any reason, it was not treated, it could cause progression for its progression. Stage AIT depends on how long it developed. Hashimoto disease is divided into 4 stages.
The disease may be both in the same phase and pass all the above stages. It is extremely difficult to predict exactly how the pathology proceeds.
Each forms of the disease has its own features of manifestation. Since the ait does not represent a serious danger to the body, and its final phase is characterized by the development of hypothyroidism, nor the first, but the second stage is no clinical signs Dont Have. That is, the symptoms of pathology is essentially combined from those anomalies that are characteristic of hypothyroidism.
Let us list the symptoms characteristic of the autoimmune thyroidity of the thyroid gland:
At postpartum, silent (asymptomatic) and cytokine-induced AIT characterized alternation of the phases of the inflammatory process. With the thyrotoxic stage of the disease manifestation clinical picture Occurs due to:
The hypothyroid stage is accompanied by the same symptoms as chronic. For postpartum Aita, the manifestation of thyrotoxicosis symptoms in the middle of 4 months is characterized in the middle of 4 months, and the detection of symptoms of hypothyroidism at the end of 5 - at the beginning of 6 months of the postpartum period.
In case of nonsense and cytokine-induced AIT, special clinical signs are not observed. If there is an ailment, still, they are manifested, they have an extremely low degree of severity. With asymptomatic flow, they are detected only during a preventive examination in a medical institution.
The photo below shows how the disease occurs in women:
Before the emergence of the first alarming signs of pathology, it is almost impossible to identify its availability. In the absence of unreasoning the patient, it does not consider it appropriate to contact the hospital, but even if it does it, it will be almost impossible to identify pathology using tests. However, when the first adverse changes in the work of the thyroid gland will begin to occur, clinical study The biological sample will immediately reveal them.
If other family members suffer or have previously suffered from such disorders, it means that you are in the risk group. In this case, attend a doctor and undergo preventive studies need as often as possible.
Laboratory studies in suspected AIT include:
If results ultrasonic research Indicate the AIT, but the clinical tests refute its development, the diagnosis is considered doubtful, and the patient does not fit into the history of the patient.
Thyroiditis can have unpleasant consequences that differ for each stage of the disease. For example, with a hyperthyroid stage, the patient can break heartbeat (arrhythmia), or heart failure arise, and this is already fraught with the development of such dangerous pathology as myocardial infarction.
Hypothyroidism can lead to the following complications:
With a myxedema, a person becomes hypersensitive to any temperature changes in a smaller side. Even banal flu, or other infectiontransferred under a given pathological condition may cause a hypothyroid coma.
However, it is not necessary to worry much - such a deviation is a reversible process, and is easily treatable. If you correctly choose the dosage of the drug (it is prescribed depending on the level of hormones and at-TPOs), then the disease during a long period of time may not remind themselves.
Ait treatment is carried out only at the last stage of its development - at. However, in this case, certain nuances are taken into account.
Thus, therapy is carried out exclusively with manifestic hypothyroidism, when the TSTG level is less than 10 honey / l, and CV. T4 reduced. If the patient suffers from the subclinical form of pathology with TSH in 4-10 honey / 1 l and with normal indicators sv. T4, then, in this case, treatment is carried out only with the symptoms of hypothyroidism, as well as during pregnancy.
Today, the most effective in the treatment of hypothyroidism are drug-based drugs based on levothyroxine. A feature of such drugs is that their active substance is as close as possible to human hormone T4. Such means are absolutely harmless, so they are allowed to be taken even during pregnancy and GW. Preparations practically do not cause side Effects, and, despite the fact that they are based on a hormonal element, they do not lead to an increase in body weight.
Levothyroxin-based drugs should be accepted "Insulated" from others drugsSince they are extremely sensitive to any "outsiders" substances. The reception is carried out on an empty stomach (half an hour before the meal or the use of other drugs) with the use of an abundant amount of fluid.
Calcium, multivitamins, iron-containing drugs, sucralfat, etc., should be taken no earlier than 4 hours after receiving Levothyroxine. SAME effective means On its basis are L-thyroxine and euticox.
Today there are a lot of analogues of these drugs, but it is better to give preference to the originals. The fact is that it is they who have the most positive effect on the patient's body, while analogs can only bring the temporary improvement in the patient's health.
If from time to time you go from the originals for generics, then you must remember that in this case the dosage correction will need active substance - Levothyroxine. For this reason, every 2-3 months it is necessary to take blood test to determine the level of TSH.
Treatment of the disease (or a significant slowdown in its progression) will give higher results if the patient avoid food causing thyroid gland. In this case, it is necessary to minimize the frequency of consumption of products containing gluten. Under the ban hit:
At the same time, you need to try to eat products enriched with iodine. They are especially useful when dealing with the hypothyoid form of autoimmune thyroiditis.
When AIT, it is necessary to take a serious seriousness to the issue of protecting the body from the penetration of pathogenic microflora. You should also try to clean it from pathogenic bacteria that are already in it. First of all, you need to take care of the cleansing of the intestine, because it is actively reproduction that harmful microorganisms. To do this, in the diet of the patient should include:
All products from the above list contribute to the strengthening of the immune system, enrich the body with vitamins and minerals, which, in turn, improves the functioning of the thyroid gland and intestines.
Important! If a hyperthyroid form of ait occurs, it is necessary to completely eliminate all products from the diet, which contains iodine, since this element stimulates the production of T3 and T4 hormones.
When ait is important to give preference to the following substances:
What is the worst way to expect? The prognosis of the AIT treatment, as a whole, is quite favorable. If there is a persistent hypothyroidism, the patient will have to take drugs based on levothyroxine until the end of the life.
It is very important to monitor the level of hormones in the patient's body, so once every six months it is necessary to pass a clinical analysis of blood and ultrasound. If during an ultrasound study, a noded seal in the scope of the scope will be seal, this should be a good reason for passing consultation from the endocrinologist.
If an increase in the nodules was observed during the ultrasound, or their intensive growth was observed, the patient appoints a puncture biopsy. The resulting tissue pattern is examined in the laboratory in order to confirm either refute the presence of a carcinogenic process. In this case, ultrasound is recommended once every six months. If the node does not have tendency to zoom, the ultrasound diagnostics can be performed once a year.