Form release

Structure

Active ingredient: xylometazoline HydroxyloroidsMiructive substances: lemonic acid monohydrate; sodium citrate dihydrate; glycerol 85%; Water for injection. Concentration of the active substance (mg): 1 mg

Pharmacological effect

Alpha adrenomimetics for local applications in LOR-Practice. local application Xylometazoline causes a narrowing of the arteriole, leads to a decrease in hyperemia and edema of the nasopharmaceous mucous membranes and a decrease in the separated secret. Distinct local action The drug is revealed in a few minutes and persists for several hours (up to 6-8 hours), manifested in the restoration of the patency of the nasal strokes, the holes of the sinuses and Eustachius pipes. The restoration of the air passability of the nasopharynx improves the patient's well-being and reduces the danger possible complicationscaused by stagnation of the mucous secret.

Pharmacokinetics

When local use, xylometazoline is practically not absorbed, therefore, the concentration in the blood plasma is very small (are not analytically determined).

Contraindications

Increased sensitivity to xylometazoline or other components of the drug. The skin's skin, the nasal mucosa and the crust formation (dry rhinitis). Replacement after hypophysometer. Application in children up to 2 years. Recruitment of glaucoma. Inhibitors of monoaminoxidase (MAO) and tricyclic antidepressants.

Application in pregnancy and breastfeeding

The effect on the ability to driving vehicles and managing the mechanism on the ability of transport and the management of machines and mechanisms is not marked.

Method of application and dose

Adults and children over 10 years old: Rinonorm, spray nasal dosage, 0.1% - 1 dose in each nasal course no more than 3 times a day. Maximum multiplicity of application should not exceed 7 times a day. The interval between the administration of the drug should not be less than 6 part 1 of the dose (one press on the piston device) \u003d 0.14 ml of solution. In order to avoid complications in the form of resumption of symptoms of the disease, the duration of continuous use of the drug should not exceed 7 days. Perfor the use of the drug Rinonorm It is recommended to free the nasal move from the secret, and during the introduction of the drug it is necessary to make a light breath through the nose.

Side effects

The simultaneous reception of three or tetracyclic antidepressants can increase the systemic effects of xylomezoline. When simultaneously receiving the drug with Mao inhibitors, the risk of increasing blood pressure is possible.

Overdose

Local reactions: a feeling of burning and dryness of the mucous membrane of the nasal cavity; rarely - the irritation of the mucous membrane of the nose, oral cavity and larynx. Side CNS: headache; Insomnia, increased excitability. The side of the cardiovascular system: arrhythmia, an increase in blood pressure: rarely - nausea; Skin reactions.

Interaction with other drugs

Precautions

special instructions

Symptoms: In rare cases of overdose arising mainly in children, arrhythmias can be observed, an increase in blood pressure, in some cases - loss of consciousness. Treatment: Symptomatic therapy under observation is shown. In serious cases, non-selective alpha-adrenoblockers can be applied to reduce blood pressure, as well as intubation and IVL. Vasomotoring drugs are contraindicated. In case of random reception of a moderate or large amount of drug inside, activated carbon and a laxative (for example, sodium sulfate) should be taken, make a stomach wash.

Rinonorms refers to vasoconducting means applied in otolaryngology. A medication is produced in the form of a nasal spray. The drug can be used in children older than 2 years. With caution, rinonorms can be used by mothers supporting breastfeeding.

Dosage form

The medication is produced in the form of a spray of nasal dosed by 0.05% and 0.1%.

Description and composition

Spray nasal dosage is a transparent, colorless solution.

As a valid component, the drug contains. In addition to it, the medication contains the following auxiliary components:

• glycerol;
• water for injections;
• E330;
• sodium citrate dihydrate.

Pharmacological group

Rinonorms refers to α-adrenomimetics for local use in LOR-Practice. The arteriole narrows, hyperemia and edema of the nasopharmaceous mucous membranes decreases and the number of separated secrets. The drug begins to act in a few minutes and the effect of it is saved to 6-8 hours. After its spraying, the passability of nasal moves, Eustachius pipes is restored.

Under the local application, the active substance is practically not absorbed, therefore the concentration in the blood plasma is small and is not analytically determined.

Indications for use

for adults

The drug is used for the following diseases:

• acute rhinitis of viral, bacterial, allergic etiology;
• acute sinusitis or chronic in the aggravation stage;
• the acute inflammation of the middle ear (spray is used to reduce the edema of the estarchy tube mucosa).

In addition, rinonorms are prescribed to prepare nasal moves to diagnostic procedures.

for kids

Spray in the dosage of 0.05% can be applied according to children over 2 years old, the drug at a dose of 0.1% is allowed to patients over 10 years.

for pregnant women and during lactation

During the navigation of the fetus rinonorms is contraindicated. With caution spray can use patients nursing breasts.

Contraindications

It is impossible to use rinonorms if the patient has been observed:

• individual intolerance to the composition of the spray;
• atrophic rhinitis;
• condition after surgical destruction or removal of pituitary
• clothing glaucoma.

Rinonorms are contraindicated in patients who are treated by Mao inhibitors and tricyclic.

With caution, the drug must be prescribed if the patient has been observed:

• arterial hypertension;
• heavy heart pathology;
• thyrotoxicosis;

special instructions

Rinonorm does not affect the ability to drive a car.

Overdose

• arrhythmia;
• raising arterial pressure;
• loss of consciousness.

Most often, the symptoms of overdose are observed in children.

Specific antidote does not exist. The victim is prescribed symptomatic therapy. In case of severe intoxication to reduce blood pressure, non-selective α-adrenoblays prescribe, also carry out intubation and IVL. If the drug by mistake is taken inside prescribed laxatives, such as sodium sulfate, give a drink and washing the stomach.

Storage conditions

Rinonorms need to be stored in place inaccessible for children at temperatures up to 25⁰c. The expiration date of the spray is 36 months, after the revealed bottle can be used for 12 months.

Analogs

Buy rinonorms without presenting a recipe. In addition to him, a lot of its analogues are sold at the pharmacy:

1. Ksilo is a complete analogue of the drug rinonorm. Produced in the form of a nasal spray of 0.05% (allowed to children 2-6 years old) and 0.1% (it can be used in patients over 6 years old). Xilo can not be pregnant and nursing patients.
2. - Polish drug, which is a complete analogue of the rinonorm. A drug is produced in the form of a nasal gel and spray. In a suitable dosage form, the drug can be used in patients older than 2 years. Prohibited pregnant and nursing.
3. Refers to replaces of rinonorm on the therapeutic group. A medicine is produced in the form of droplets and spray. The drug happens in several dosages, which allows it to apply in patients of various ages, including children of the first year of life. Can use women in position and nursing breasts.
4. Naphtizin plus is a substitute for the drug rinonorms on the therapeutic group. A medication is produced in the form of nasal droplets, which, with riti, can be used in children over 12 months, women in position and supporting natural feeding during lactation.
5. - The drug is the company of Zentiv, which is a substitute for Rinonorm on the clinical and pharmacological group. The medicine is produced in the form of spray, drops and nasal Mazi.. The drug can be used in patients older than 2 years, including women in position and nursing breasts. The drug is contraindicated in allergic rhine.

To select an analogue of the drug Rinonorms should only attending a doctor, since each of the medicines has its own characteristics.

Price

The cost of Rinonorm is an average of 70 rubles. Prices fluctuate from 56 to 173 rubles.

Do you know what medicines are the most sold? These are xylometazoline-based vessels. Not surprised? Still would! After all, everyone knows how difficult it is to live with a runny nose, and they eliminate him quickly and for a long time. Their number includes rinonorms. What does it help, why is buyers in demand and what can be dangerous?

We are accustomed that imported medicines are expensive. But in this row there are pleasant exceptions. One of the inexpensive and high-quality drugs produces German pharmaceutical company "Merkel GmbH". This is a rinonorm. What does he help?

These are drops for the nose produced in the form of spray. They belong to vesseloring drugs for local applications, which are widely used in the treatment of ENT diseases. "In scientific" is alpha adrenomimetics. And this means that his active Component If the nasal mucosa appears, the narrowing of the vessels is caused, reduces the swelling, reduces the separated secret (simply speaking, snot). It acts very quickly: the nose begins to breathe after 15-20 minutes, and the effect is saved from 6 to 8 hours, which makes it appropriate to use the spray at night.

Restoring the passability of the nasopharynx, the medicine not only improves the health of the patient, but also prevents complications associated with stagnation of mucous drugs. The main component in the composition of drugs - xylometazoline in the amount of 5 mg in the drug for children and 10 mg - for adults.

He is released without a recipe. Registration This remedy passed back in 2004. For 13 years, it has managed to earn a good reputation in practitioners and patients.

When to apply it?

This is a symptomatic medicine, that is, it is suitable for the treatment of acute states, but is not suitable for getting rid of chronic LOR pathologies. Here are the main indications for the use of Rinonorm:

• rhinitis of allergic, viral or bacterial nature;
• sinusitis;
• middle Otitis (in order to reduce eternal edema);
• polleoz.

The drug is also used at the preparation stage for diagnostic procedures in the nasal cavity.

Who can he harm?

Contraindications for the use of rinonormors are related to the fact that it has a strong vesseloring effect and overcourses the mucous membrane, and with long use it can even cause its burn. Taking into account these features, the tool is prohibited in such pathologies and states:

• childhood up to 2 years;
• pregnancy, breastfeeding;
• treatment with antidepressants or Mao inhibitors;
• rinitis with mucous atrophy;
• clotted glaucoma;
• diabetes;
• rehabilitation after a pituitary operation.

Important! With great care (only with the permission of the doctor), the spray can be used in hypertension, diseases of the kidneys and SCCs, inflammation of the prostate gland.

How safe is it?

Rinonorm produces a quick effect, but it, like other means based on adrenomimetics, is able to provoke adverse reactions. Most often it is:

• signs of irritation of the mucous - tingling, burning, dryness, strengthening of the secretion of mucus, sneezing;
• rashes on skin cover;
• headache, pulse, increase blood pressure, sleep problems, excessive excitability.

How to use spray?

Rinonorm spray is very convenient to use. According to the instructions for use, it should be done like this:

• patients with 10 years and adults are suitable for 0.01% solution. It should be injected at 1 dose in each nasal pass no more than 3 p. per day with a 6-hour interval between procedures. The maximum number of applications is 7 times. At one press on the piston in the nose, 0.14 ml of the composition falls;
• children from 2 to 10 years old should be used 0.05% nasal spray in this way: 1 injection up to 3 p. A day with a gap at 6 o'clock.

Important! To avoid complications, addiction and addiction, the therapy cannot be carried out longer than 7 days.

Xilomeazoline "Relatives" of the drug

Spray has affordable price - from 50 to 60 rubles, and the children's form of the drug costs somewhat more expensive adult - about 80 rubles. A variety of rinonormal analogues with exactly the same composition are much more expensive. If they are released in drops, they are contraindicated to kids up to 6 years, and the described means can be used from 2 years. Therefore, it is hardly advisable to look for analogs. The only remark that is presenting some patients to this medicine is a short shelf life. But this is explained by the fact that it does not contain preservatives. Taking into account the low cost, it can be purchased with each new disease.

Here are the most famous analogues of this nasal spray:

• cheaper - Galazolin (Poland, about 33-3-38 rubles);
• in the same price category - xylene (domestic medicine, 66-68 rubles), xylometazoline (60-62 rubles), Rinorus (Russia, 71-80 rubles);
• somewhat more expensive - rhinostop (Russian, 90 rubles), Infpostad Reno (German spray, from 85 rubles), fornasses (India, 95-104 rubles), Tizin Ksilo (98-103 rubles);
• dear - Snup (Germany, 119-139 rubles); Orivin (Switzerland, 153-167 rubles); Ximeline (produced by the Danish and Norwegian branches of the company "NIKOMED", 190-230 rubles.)

AND active substance, and its concentration in these medicines is the same. Minus, regardless of the manufacturer, too, in all the same: all vasoconductants long use cause the opposite effect - hypertrophy of the mucous membrane and chronic nasal congestion. Popular deryvin complex acts faster, as it also contains the bromide, but it is allowed only from 18 years.

Rinonorm is a remedy for the Western European manufacturer, so you can count on its high quality. In addition, it is not distinguished by the transcendental price and guaranteed to save the nose to silence. But it must be remembered that the elimination of mucus with ritin is not an end in itself. The main thing is to cure the disease, and not to remove an unpleasant symptom. In addition, it is possible to apply rinonorms only a limited period.

Vasomotoring drug for local application in LOR Practice

Active substance

Release form, composition and packaging

◊ Spray nasal dosage (for children) 0.05%

◊ Spray nasal dosage 0.1% in the form of a transparent, colorless solution.

Auxiliary substances: lemon acid monohydrate, sodium citrate dihydrate, glycerol 85%, water d / and.

15 ml - dark glass vials (1) with a dosing device and a nose nozzle - packs cardboard.

pharmachologic effect

Alpha adrenomimetics for local use in LOR-Practice.

Under the local application of xylomezoline causes the narrowing of the arteriole, leads to a decrease in hyperemia and edema of the nasopharmaceous mucous membranes and a decrease in the separated secret. The distinct local action of the drug is revealed in a few minutes and is preserved for several hours (up to 6-8 hours), manifested in the restoration of the patency of the nasal strokes, holes of the sinuses and Eustachius pipes. The restoration of the nasopharynk air maintenance improves the patient's well-being and reduces the risk of possible complications caused by the stagnation of the secrecy.

Pharmacokinetics

Under the local application, xylometazoline is practically not absorbed, therefore, blood concentrations are very small (they are not analytically determined).

Indications

Rinonorms are used as symptomatic therapy in the following diseases and states:

- acute viral or bacterial rhinitis;

- sharp allergic rhinitis;

- acute sinusitis or aggravation of chronic sinusitis;

- acute average otitis (to reduce the edema of the mucous membrane of the Eustachius pipe);

- Preparation of the patient for diagnostic procedures in nasal strokes.

Contraindications

- atrophic (dry) rhinitis;

- Clothing glaucoma;

- condition after hypophysometer;

- simultaneous reception of Mao inhibitors and tricyclic antidepressants;

- children's age up to 2 years (for spray for children);

- children under the age of 10 years (for spray for adults);

- increased sensitivity to xylometazoline or other components of the drug.

FROM caution It should be applied to the drug when arterial hypertension, severe heart disease, hyperthyroidism, sugar diabetes and patients hosting.

Dosage

Adults and children over 10 years old Prescribed by rinonorms spray nasal 0.1% 1 dose (1 pressing on the piston device) in each nasal course not more than 3 times / day.

Children aged 2 to 10 years Prescribed rinonorms spray nasal for children 0.05% 1 dose (1 pressing on the piston device) in each nasal course not more than 3 times / day.

Maximum can be used the drug not more than 7 times / day. The interval between the introduction of the drug should not be less than 6 hours.

The amount of fluid entering the nasal course of the patient (1 dose) is 0.14 ml of solution.

In order to avoid complications in the form of resumption of symptoms of the disease, the duration of continuous use of the drug should not exceed 7 days.

Before applying the drug, the nasal moves from the secret should be released. During the introduction of the drug, you should make a light breath through the nose.

Side effects

Local reactions: feeling of burning and dryness mucous membrane of the nasal cavity; Rarely - irritation of the mucous membrane of the nose, oral cavity and larynx.

Treatment: Symptomatic therapy under observation is shown. In serious cases, non-selective alpha-adrenoblockers can be applied to reduce blood pressure, as well as intubation and IVL. Vasomotoring drugs are contraindicated. In case of random reception of a moderate or large amount of drug inside, a laxative means should be taken (for example, sodium sulfate), make the stomach washing.

Medicinal interaction

The simultaneous reception of three or tetracyclic antidepressants may increase the systemic effects of xylometazoline.

With simultaneous treatment of the drug with Inhibitors of MAO, the risk of increased blood pressure is possible.

Rinonorm, from which this helps vasoconstrictor drug. The medicine reduces hyperemia and edema of the nasopharmaceous mucous membranes. It is actively used in Otoloringology. The drug rinonormal instructions recommends using sinusitis, rhinitis, otitis.

Composition and form of release

Rinonorms, from which it helps with a cold, produced in the form of droplets in the nose (transparent liquid, odorless). They are packaged into bottles from dark glass with a volume of 15 or 10 ml., Placed in cardboard packaging (one bottle in one pack). For more convenient use is equipped with a specialized dosing nozzle.

Depending on the variety of nasal spray rinonorms, the composition of this drug may contain either 5 mg. (for children) or 10 mg. (for adults) active substance xylomezoline hydrochloride. In addition, there are such auxiliary compounds in the preparation as: 85% glycerol, citric acid monohydrate, sodium citrate dihydrate, as well as water intended for injection.

Pharmacological properties

The drug rinonorms in its clinical and pharmacological group is an alpha adrenomimetic, which is used to treat ENT diseases. Xylometazoline under local use contributes to the narrowing of the arteriole, decrease in the swelling and hyperemia of the nasopharmal mucosa and reduce the separated secret. Already 5-10 minutes after the local use of the drug, a distinct effect is manifested, which is preserved within a few hours.

Rinonorme Reviews confirm that the use of the drug allows you to quickly restore the permeability of the nasal moves, Eustachius pipes and holes of the sinuses. Due to the restoration of the air passability of the nasopharynx, an improvement in the health of the patient occurs. Also, the instructions for Rinonormum reported that the use of the drug for ENT diseases, reduces the risk of possible complications that occur with a long-term stagnation of the secrecy.

Medicine Rinonorm: from what helps

Indications for use are as follows:

• Acute sinusitis and aggravation of chronic sinusitis.
• Acute rhinitis Bacterial and viral origin.
• Acute allergic rhinitis.
• Acute Middle Otitis (to reduce the edema of the mucous membrane of the Eustachius pipe).

Rinonorms are also prescribed during the preparation of the patient to conduct diagnostic procedures in the nasal strokes.

Contraindications

Rinonorm Instructions for use prohibits using:

• dry or atrophic rhine;
• clothing type glaucoma;
• age of patients up to 2 years;
• increased sensitivity to the main and auxiliary components of the drug connection.

Preparation Rinonorm: Instructions for use

The dosage is selected individually for each patient, depending on the degree of obstruction of the nasal moves during the cold. The following recommended drug dosages are prescribed in the rinonorm instruction: children who have reached the age of 6, and adults prescribe the drug in the form of a spray (for adults) 1 dose (corresponds to one pressing of the piston device) into each nostril 1-3 times a day. With a single press of the piston device in the nasal pass, the amount of liquid is equal to 0.09 ml of solution (0.09 ml of xylometazoline, respectively).

For the treatment of children aged 2-6 years, a rinonorm spray for kids is used for 1 pressing in each nasal passage, 1-3 times a day. With a single press of the piston device, the amount of liquid is 0.045 ml of the solution (respectively, 0.045 ml xylometazoline, respectively). Before spraying the drug in the nasal stroke, they need to be cleaned of the secrecy of the secret. When the solution is introduced, it should be a little inhale through the nose.

Do not use rinonorms more often than recommended in the instructions for the drug (3 times a day). Rinonorm treatment should be discontinued immediately after the disappearance of the symptoms of the disease. The maximum duration of the course of treatment with this drug is 7 days.

If you need a re-course of treatment with rinonorm, it is started only after 3-4 day break. If the patient wants to use rinonorms for a long period, for example, for treatment chronic rhinitisthen you need to seek advice to your doctor who will control further application drug (as there is a threat to the development of atrophy of the mucous membrane of the nose).

Side effects

Pretty rarely, however, the following side effects may appear:

• increased excitability;
• headaches;
• an increase in blood pressure;
• arrhythmia;
• insomnia;
• nausea;
• irritation of mucous membranes;
• burning or itching;
• rash on the skin.

Rinonorm for pregnancy

In agreement with the instructions for the drug, it is not recommended to use rinonorms during pregnancy. This is due to the fact that there is no data on the use of rinonorm in pregnancy and lactation, also not conducted clinical researches on this issue. It is not recommended to use rinonorms during pregnancy and for the reason that the main active substance of the drug is xylometazoline, which has a detrimental effect on the development of the fetus.

Analogs

Among the main analogues of the rinonorm can be allocated:

• Galazoline;
• Spray for cleaning;
• Brizolin;
• Taiss Nazolin;
• Nose asterisk;
• Xylene;
• Xilomeazoline;
• Influine;
• Ximeline;
• Nostin;
• Olint;
• Rinomaris;
• Orinary;
• Rinorus;
• Snup;
• Rosotop;
• Eucazolin Aqua;
• Sanarin-xylo;
• Tizin Ksilo;
• Espazolin;
• Super Nose;
• Pharmazoline.

Price Rinonorm, where to buy

As a rule, the average price of Rinonorm in Russia (vial of 15 ml.), And both an adult and children varies from 65 to 75 rubles. The cost of spray in Kiev reaches 100 hryvnia.