Antiseptic for topical application in gynecology
◊ Vaginal suppositories color, white or white with a yellowish tinge, torpedo-shaped, marbling of the surface is allowed.
Excipients: polyethylene oxide base (polyethylene oxide 1500, polyethylene oxide 400).
5 pieces. - contour cell packaging (1) - cardboard packs.
5 pieces. - contour cell packaging (2) - cardboard packs.
Antiseptic preparation for topical use.
Active in relation to gram-positive and gram-negative bacteria- Treponema pallidum, Chlamydia spp., Ureaplasma spp., Neisseria gonorrhoeae, Gardnerella vaginalis, Bacteroides fragilis; the simplest-Trichomonas vaginalis; viruses- Herpes simplex types 1 and 2.
Does not interfere with the functional activity of lactobacilli.
Remains active (although somewhat reduced) in the presence of blood, pus.
Practically not absorbed from the gastrointestinal tract. After accidental ingestion, 300 mg C max is reached after 30 minutes and is 0.206 μg / L. It is excreted mainly in the feces (90%), less than 1% is excreted in the urine.
- prevention of sexually transmitted diseases (including gonorrhea, trichomoniasis, chlamydia, ureaplasmosis, genital herpes);
- prevention of infectious and inflammatory complications in obstetrics and gynecology (before surgical treatment gynecological diseases, before and after diathermocoagulation of the cervix, before intrauterine studies);
- treatment of chronic exo- and endocervicitis, vaginitis (including nonspecific, mixed, Trichomonas).
- hypersensitivity to the components of the drug;
For prevention sexually transmitted diseases 1 soup is prescribed once. The drug should be used no later than 2 hours after intercourse.
For treatment appoint 1 soup. 2 times / day for 7-10 days. If necessary, it is possible to extend therapy up to 20 days.
Possible: allergic reactions, itching that pass after the drug is discontinued.
Currently, no cases of overdose of the drug Geksikon D have been reported.
Hexicon D is not compatible with detergents containing an anionic group (saponins, sodium lauryl sulfate, sodium carboxymethyl cellulose) and soaps. The presence of soap can inactivate
Geksikon ® D, 10 suppositories
Registration number
International non-proprietary name
Chlorhexidine
Vaginal suppositories
Composition for one suppository
Active substance: chlorhexidine bigluconate solution 20% - 42.6 mg (in terms of chlorhexidine bigluconate - 8 mg);
Excipients: a mixture of macrogols: macrogol 400 - 2%, macrogol 1500 - 98%.
Torpedo-shaped suppositories, white or white with a yellowish tinge. Marbling and the presence of an air rod and a funnel-shaped depression on the cut are allowed.
Antiseptic
Geksikon ® D is an antiseptic preparation for local (intravaginal) use, is active against protozoa, gram-positive and gram-negative bacteria, viruses, including Treponema pallidum, Chlamidia spp., Ureaplasma spp., Neisseria gonorrhoeae, Trichomonas vaginalis, Gonardis vaginalis Bacteroides fragilis, Herpes simplex type II. Some strains of Pseudomonas spp., Proteus spp. Are weakly sensitive to the drug, as well as acid-resistant forms of bacteria, bacterial spores. Geksikon ® D does not interfere with the functional activity of lactobacilli.
Pharmacokinetics
Systemic absorption with intravaginal use is negligible.
The drug Geksikon ® D, vaginal suppositories, is indicated for the local treatment of infections of the genital tract in children, is used in pediatric gynecology in girls from 6 months. and before the onset of menarche.
Treatment of vulvovaginitis (including nonspecific, mixed, gonorrheal, Trichomonas), bacterial vaginosis.
Prevention of sexually transmitted diseases (syphilis, gonorrhea, trichomoniasis, chlamydia, ureaplasmosis), infectious and inflammatory complications in pediatric gynecology (for example, before surgical treatment of gynecological diseases).
Hypersensitivity to drug components
It is possible to use the drug during pregnancy and during breastfeeding if the intended benefit to the mother outweighs the potential risk to the fetus or child.
Having previously released the suppository from the blister strip packaging, it is inserted into the vagina in the supine position.
For treatment: 1 suppository 2 times a day, for 7-10 days. If necessary, it is possible to extend the course of treatment up to 20 days.
For the prevention of sexually transmitted diseases: 1 suppository no later than 2 hours after intercourse.
Frequency adverse reactions according to the WHO classification: very often (≥10%), often (≥1% and<10%), нечасто (≥0,1% и <1%), редко (≥0,01% и <0,1%), очень редко (<0,01%), частота неизвестна (не может быть определена на основании имеющихся данных).
Rarely: allergic reactions, itching that pass after the drug is discontinued.
Frequency unknown: severe allergic reactions, including anaphylaxis.
If any of the side effects indicated in the instructions are aggravated or you notice any other side effects not listed in the instructions, inform your doctor.
Currently, no cases of drug overdose have been reported.
Not compatible with detergents containing anionic group (saponins, sodium lauryl sulfate, sodium carboxymethylcellulose) and soaps if they are administered intravaginally. The toilet of the external genital organs does not affect the effectiveness and tolerability of vaginal suppositories Geksikon ® D, because the drug is used intravaginally.
Geksikon ® D retains activity (although somewhat reduced) in the presence of blood, pus. The suppositories are reduced in size, designed specifically for the treatment of girls.
Geksikon D is an antiseptic that is effectively used locally in gynecological practice for some pathological processes, which I will discuss later. It is necessary to read the instructions for use of this drug.
What is the composition and form of release of the drug Geksikon D (suppositories)?
The drug is produced by the pharmaceutical industry in the form of vaginal suppositories, they are whitish-yellow in color with slight marbling on the surface, their shape is torpedo-like. The active substance is chlorhexidine bigluconate in an amount of eight milligrams.
Excipients Geksikon D: polyethylene oxide base, which consists of polyethylene oxide 1500, and also contains polyethylene oxide 400. The product is placed in cell packs of five pieces. It is recommended to store vaginal suppositories out of the reach of children, while it should be darkened.
The temperature should not rise more than 25 degrees, you can put the medicine in the refrigerator chamber, you cannot freeze the candles. It is recommended to sell the drug no later than two years from the date of manufacture of the candles, otherwise they will expire.
You can buy suppositories at the over-the-counter pharmacy department. If, after removing the suppositories from the cell packaging, they are of a different color than provided for in the instructions for the medicine, it is not recommended to use such a drug.
What is the Geksikon D (candles) action?
Antiseptic preparation Geksikon D is intended for topical use. It is active against such bacteria, I will list them: Treponema pallidum, Ureaplasma spp., Bacteroides fragilis; Neisseria gonorrhoeae, Chlamydia spp., Gardnerella vaginalis, in addition, Trichomonas vaginalis, as well as Herpes simplex viruses belonging to types 1 and 2.
Hexicon D retains its therapeutic activity in the presence of blood and purulent contents, although the effect of the drug is somewhat reduced. The drug is practically not absorbed from the digestive tract. After accidental ingestion of the medication, Cmax occurs after 30 minutes. It is excreted through the intestines, and less than 1% leaves the body in the urine.
What are the Geksikon D (candles) indications for use?
Hexicon D is used for the prevention of sexually transmitted diseases, for example, with gonorrhea and syphilis, with genital herpes, with ureaplasmosis, with trichomoniasis and chlamydia.
Vaginal suppositories are prescribed for the prevention of complications of an infectious and inflammatory nature in gynecological practice (before surgery, with diathermocoagulation of the cervix and after it, as well as suppositories are effective before intrauterine examination.
In addition, suppositories are used to treat exocervicitis and endocervicitis, a drug is prescribed for vaginitis of various origins: with Trichomonas, nonspecific, and also with mixed forms. The use of the drug involves a preliminary consultation with a gynecologist.
What are the Geksikon D (candles) contraindications for use?
Among the contraindications for vaginal suppositories Geksikon D instructions for use notes the presence of allergic reactions, in addition, the drug is not prescribed for hypersensitivity to the components of the drug.
What are the Geksikon D (suppositories) use and dosage?
In order to prevent sexually transmitted diseases, a woman is prescribed one suppository once a day. The drug must be used no later than two hours after intercourse. Vaginal suppositories should be used as directed by the attending doctor.
For a therapeutic purpose, candles are prescribed one piece twice a day for ten days or one week. If necessary, the doctor can extend the treatment up to twenty days.
The drug Geksikon D is not compatible with the so-called detergents, which contain an anionic group, these include sodium lauryl sulfate, saponins and sodium carboxymethyl cellulose. In addition, the medicine is not used with soaps, since they can inactivate chlorhexidine, respectively, before using the suppositories, the soap residues should be thoroughly washed off.
Overdose of Geksikon D (suppositories)
At present, there is no information on an overdose of the Hexicon D. vaginal suppositories. In that situation, if the suppositories are swallowed for some reason, it is necessary to immediately rinse the stomach, after which you need to consult a doctor, especially if the person's well-being worsens.
What are the side effects of Geksikon D (candles)?
In some cases, an allergic reaction occurs to the use of suppositories, while a woman may complain of itching in the perineal region, which disappears after the immediate withdrawal of the drug.
If the itching is unbearable, in this situation the patient should consult a gynecologist, most likely, she will have to cancel the medication, and prescribe an analogue of the drug Geksikon D.
What are the analogues of Geksikon D (candles)?
Amident, Geksikon, Hibiskrab, Tsiteal, Chlorhexidine, Katejel C, Plivasept P, Chlorhexidine bigluconate, these medicines can be counted among analog drugs.
Conclusion
Vaginal suppositories can be used only as directed by a gynecologist, in accordance with the available indications for the use of the drug. If severe itching occurs, the patient should consult a specialist.
Instructions for the use of Geksikon suppositories describe in detail their use for the treatment of various diseases of the urinary system; they can also be prescribed in the course of therapy for infections of the reproductive system in women of any age, including children.
The product is an antiseptic and disinfectant for external use. Its bactericidal properties provide a quick effect in the treatment of bacterial disorders.
Geksikon suppositories are available in the form of suppositories, that is, they are solid at room temperature and melt at body temperature. They are in the form of a cylinder with a slightly pointed end. White color. The surface is smooth.
Suppositories are sold in a cardboard box containing two contoured cellular plates of 5 suppositories each. Instructions are also attached to the drug.
The medicinal substance of the Geksikon suppositories is chlorohexidine bi-gluconate in the amount of 16 mg in each individual dose (suppository). Additional working components: polyethylene oxide (1500) and (400). These substances form the mass of the suppository (3.1 g) and ensure its uniform melting inside the body.
Chlorine-hexidine bi-gluconate is an antispeptic agent that has a bactericidal effect, destroying bacteria. The mechanism of its action is that it destroys cell membranes by osmotic dissociation, that is, it promotes their disintegration into ions.
The drug is effective against many infectious bacteria, while it is useless for the treatment of viruses, acid-resistant microorganisms, fungi. In the vagina, the Hexicon suppository melts, enveloping the mucous membrane, while not being absorbed into the bloodstream.
The drug Geksikon is used against such bacterial infections:
Suppositories work well even in the presence of pus and blood. Suppositories can also be used during menstruation.
The drug Geksikon, in addition to the antibacterial, has a spermicidal effect. Therefore, it can be used before intercourse - not only for the prevention of genital infection, but also as a contraceptive. However, it should be borne in mind that the constant use of suppositories as a countermeasure to conception is not provided for in the instructions for use.
Geksikon suppositories (instructions for the use of suppositories describe their use in therapy and prophylactic treatment against diseases arising from infection through sexual contact) can be used in different circumstances.
For example:
In case of fungal diseases (candidiasis), Geksikon suppositories are not used, due to their ineffectiveness.
The effectiveness of the use of Geksikon suppositories for the prevention and in the complex therapy of many well-known bacterial infections, such as gonorrhea, gardanerella, chlamydia, syphilis, trichomoniasis, genital herpes, mycoplasmosis, ureaplasmosis, has been repeatedly proven in practice.
But suppositories are also used as a disinfectant to prevent possible inflammatory complications before research, childbirth, cleaning, and surgery.
Candles should not be used in cases:
Suppositories are used only for the treatment of female diseases. Before you start taking suppositories, you should test the drug for individual intolerance.
Suppositories are used by inserting them into the vagina.
They are used:
The introduction of the suppository requires taking a horizontal position, preferably with a raised pelvis (you can put a pillow under it), followed by rest for one to two hours.
Geksikon suppositories are extremely convenient to use, as they do not require douching before use. However, increased vaginal discharge during the treatment period necessitates more intensive use of daily hygiene products (pads, tampons).
To increase the therapeutic effect of a course intake of Geksikon suppositories, it is recommended to avoid sexual intercourse, since their continuation during treatment can contribute to re-infection and reduce the effectiveness of the process.
Hexicon candles (instructions for use allow the use of the product during pregnancy) are absolutely safe and do not affect either the mother's body or the fetus. The need for use can be caused by a weakening of immunity, changes in the vaginal microflora, due to the restructuring of the female body.
Such processes violate the immune system and allow infectious agents to infect the organs of the intimate sphere. If this is not stopped in time, then the accumulation of harmful biological forms exceeding the norm can negatively affect the fetus, infecting it.
The suppository dissolves inside the vagina, without getting into either the gastrointestinal tract, or the blood, or the placenta. To be sure that the drug Geksikon is completely safe, a woman can consult a specialist to identify allergic effects to the main active ingredients.
The general effect of exposure to suppositories is the formation of normal microflora in the vagina, which is important for the course of pregnancy without complications. Hesikon is also used after childbirth - it counteracts purulent pathologies that can occur on fresh sutures and in the unrecovered birth canal.
During the period of breastfeeding, the possible risks of genital infections increase, since the immune system does not immediately recover after childbirth. After all, the body's main resources are directed to lactation.
Since suppositories are not absorbed into the bloodstream, their use is permitted during breastfeeding. An exception may be allergic manifestations (itching, burning, rashes).
Dosages:
Method of administration during pregnancy: insert the suppository into the vagina to the depth of one finger, preferably lying down. For convenience, you can bend your knees. During the period of use of the suppository, hygiene is carried out without using soap (instead of it, you can use potassium permanganate in a weak solution).
For the treatment of girls from 6 months to the beginning of menstruation, Geksikon D suppositories are used. This drug has a twice-reduced dosage of the active substance. For children, candles are produced in the form of single doses weighing 8 mg of white color, with a consistency resembling paraffin. Candles are odorless. The box contains two plates with cells, 5 suppositories each.
As a positive factor in the use of the drug, one can name the absence of violations of the vaginal microflora. Remains of suppositories are excreted through the intestines.
For use, the Hexicon candle is removed from the cell and inserted into the vagina, after which it is recommended to lie down with a slightly raised pelvis. Usually two suppositories are prescribed per day. For the general course of admission, you will need 20 suppositories or two packages of the drug.
Geksikon candles (instructions for use allow the use of the drug during the period of menstruation, if their beginning occurred during the course of treatment) create an acidic environment. Since blood is alkaline, it can reduce the effectiveness of the suppository by neutralizing the environment it has created.
Symptoms indicating a tendency to side effects from taking Geksikon suppositories are individual in nature.
They are usually expressed like this:
Allergy can be expressed in the urge to urinate, itching, burning, swelling of the mucous membrane, bleeding of the labia and vagina.
Suppositories are used exclusively by inserting a suppository into the vagina, that is, they are not intended to treat infections on other mucous membranes. However, the components that make up Hexicon (chlorohexidine bi-gluconate) can be used to treat gingivitis.
In this case, the side effects can be unexpected, such as staining the teeth. These symptoms do not apply to Geksikon suppositories, since suppositories are not intended for the treatment of dental diseases.
Directions:
There were no established cases of overdose with Geksikon suppositories (the medicine does not harm health and does not disrupt the functioning of the body, being well tolerated). It is worth taking special care to treat the individual manifestations of the effect of intolerance to some of the constituent components of the candles.
This applies to reactive reactions (itching, burning, rashes at the site of the action of suppositories). After all, if such reactions exist, then they will disrupt the productive course of treatment. As a rule, the manifestation of undesirable reactions to the drug, including allergic ones, with rashes and itching, stops simultaneously with the end of the intake.
Therefore, unexpected side effects can make you want to stop treatment, which should not be done right away. As a rule, sometimes you need to be patient. Usually, the first reaction to the drug in the form of a burning sensation is temporary and does not manifest itself in the future.
If the painful effects are unbearable and cause a persistent urge to urinate, then the remains of the suppositories should be washed off with soap and water and after a while try to repeat the introduction of the drug into the vagina again. As a rule, repeated use does not cause irritation.
How to deal with unpleasant side effects:
The action of Geksikon is neutralized with an ordinary soap solution. This should be taken into account and not used for douching soap and formulations based on it. Hexicon is also not used concurrently with iodine-based drugs. It is permissible to use candles together with benzalkonium (chloride), cetrimonium (bromide).
There are also some substances that increase the effectiveness of the effect of chlorohexidine on the mucous membrane, for example, ethanol. Therefore, taking ethanol-based drugs during the suppository treatment period will be beneficial.
After purchasing, suppositories must be kept at a temperature that prevents them from melting, which begins at 23 degrees Celsius - that is, the ideal conditions for the drug are a refrigerator. Shelf life of Geksikon candles from the date of issue is no more than three years.
Geksikon suppositories (instructions for use of this medication describe the dosage and release forms of suppositories) are non-prescription drugs, therefore they are available for purchase at any pharmacy without a special form from a doctor.
Usually Geksikon candles are packed in a cardboard box containing two plastic honeycomb shells of 5 pcs. suppositories in each (16 mg - the weight of each individual dose). Such packaging is sold at a price of 200 rubles. Geksikon D candles for children are also sold in over-the-counter pharmacies. One box contains 10 doses of 8 mg each.
Doses are packed in a mesh casing - 5 pcs. in each. Geksikon D can be bought at a price of 250 rubles. per box.
The main substitutes for Geksikon are drugs that are used to treat a similar spectrum of diseases and have a comparable effect on the body. As a rule, in the case of Hexicon, only drugs containing a chlorohexidine solution can act as complete analogs.
There are few of them:
Geksikon D (form - suppositories) belongs to the category of antiseptics and antimicrobial drugs for the treatment of gynecological diseases. The instructions for use are characterized by the following features:
Geksikon D is an antiseptic agent for local use in gynecology.
Dosage form- vaginal suppositories: torpedo-shaped, white or white with a yellowish tinge, marble coloring of the surface is possible (5 pcs. In blisters, 1 or 2 packs in a cardboard box and instructions for use of Hexicon D).
Composition of 1 suppository:
The active substance of the drug, chlorhexidine, is an antiseptic that is active against the following microorganisms:
Some Proteus spp. Strains are weakly sensitive to chlorhexidine. and Pseudomonas spp. The drug is not effective in diseases caused by acid-fast bacteria and bacterial spores.
The drug does not interfere with the functional activity of lactobacilli. Remains active (albeit somewhat reduced) in the presence of pus and blood.
With intravaginal use, the systemic absorption of chlorhexidine is negligible.
Suppositories Geksikon D are used for the local treatment of genital infections in pediatric gynecology in girls from 6 months of age to the onset of menarche:
The use of Geksikon D suppositories is contraindicated in the presence of hypersensitivity to any of the components in the composition of the drug.
Suppositories are not used to treat girls under 6 months of age.
The suppository is inserted into the vagina in the supine position, having previously been freed from the blister strip packaging.
For medicinal purposes, 1 suppository is prescribed 2 times a day for a course of 7-10 days, in some cases the doctor may extend the treatment up to 20 days.
For the prevention of sexually transmitted diseases, a single use of 1 suppository is recommended no later than 2 hours after intercourse.
Geksikon D is generally well tolerated. In very rare cases (< 0,1%) возникают зуд и аллергические реакции, которые проходят после отмены препарата.
Overdose cases have not been reported to date.
Geksikon D suppositories have a reduced size compared to Geksikon suppositories (especially for the treatment of girls).
The drug is not contraindicated for use during pregnancy and lactation.
Suppositories are allowed to be prescribed to girls from 6 months of age.
Hexicon D is incompatible with detergents containing an anionic group (sodium lauryl sulfate, sodium carboxymethylcellulose, saponins) and soaps used intravaginally. The toilet of the external genital organs with soap does not affect the effectiveness of the suppositories, however, the remains of the detergent must be thoroughly washed off before the administration of the drug.
Analogs of Geksikon D are: Betadine, Geksikon, Iodovidon, Iodosept, Fluomizin, Chlorhexidine.
Store at a temperature not exceeding 25 ° C out of the reach of children, protected from light and moisture.
Shelf life is 2 years.