In pursuit of a slim figure, some women are ready to do anything, even take drugs that are not intended for this. The main factor in the use of Glucophage Long 500 is type 2 diabetes, but girls use it for weight loss. This choice is due to the fact that the drug stimulates the excretion of sugar, is indicated for morbid obesity. The use of medication for weight loss by healthy people is not recommended by doctors.

Composition and dosage form Glucophage Long 500

The drug is produced by the French pharmaceutical company MERCK SANTE. The drug is presented in the form of oval white tablets. The active substance of the composition is metformin hydrochloride, which is 500 mg per tablet. Additional components:

• microcrystalline cellulose;
• hypromellose;
• povidone;
• carmellose sodium;
• magnesium stearate.

Functions of Glucophage Long 500

Metformin, the active ingredient in the formulation, lowers blood sugar levels, which rise with food intake. This is a natural process with the inclusion of the pancreas. It secretes insulin, which neutralizes glucose to fat cells. The active substance metformin produces an increase in the level of glycogen production, acts on the enzyme glycogen synthetase, increasing the transport capacity of membrane-type glucose transporters.

The drug is involved in the breakdown of sugars, correction and normalization of lipid metabolism. Functions of tablets:

• accelerates the elimination of simple sugars from food,
• normalizes the processes of metabolism and digestion;
• protects the organs of the gastrointestinal tract from toxins and toxins;
• creates ideal conditions for burning fat, removing cholesterol.

The hypoglycemic drug is taken orally, belongs to the group of biguanides, reduces the content of glucose in the blood plasma. Since the drug is not an insulin secretagogue, hypoglycemia does not occur. Glucophage Long increases the sensitivity of receptors located on the periphery to insulin, the utilization of sugar by cells. By inhibiting the processes of gluconeogenesis and glycogenolysis, glucose production by the liver decreases, and its absorption in the intestine slows down.

Results from taking Glucophage Long 500 for weight loss

Patients who took Glucophage Long 500 mg slimming tablets noted that the drug helps to cope with extra pounds. Such effects are explained by the actions of the drug:

1. Normalizes blood sugar levels. The drug reduces the increased concentration of glucose and leaves the normal level at the same level.
2. Accelerates the process of fatty acid oxidation. Due to this, the digestion process improves, minerals and vitamins are more fully absorbed.
3. Glucophage Long prevents the absorption of natural carbohydrates and sweets, so the body does not accumulate extra empty calories and the amount of insulin does not increase. Due to this scheme, calories are not processed into fat, and the insulin produced reduces appetite and prevents hunger from manifesting for a long time.
4. Normalizes fat (lipid) metabolism - takes control of the breakdown of carbohydrates to fats.
5. It does not help to burn the already accumulated fat layer - for this you need to play sports and limit food.
6. Normalizes the work of the pancreas.
7. To obtain the desired result, it is necessary to balance the acidity of gastric juice, avoid overloading, because the accumulation of lactic acid adversely affects the effect of the drug.

Indications for use Glucophage Long

In medical practice, Glucophage is intended for the treatment of diabetes. Indications for its use:

• Diabetes mellitus type 2 (non-insulin dependent), accompanied by obesity. It should be combined with physical activity and diet, other hypoglycemic drugs.
• Elevated sugar levels (maintenance monotherapy) without signs of obesity and with undiagnosed diabetes mellitus.
• Overweight without diabetes - is prescribed only by an endocrinologist or therapist in combination with diet and the required level of physical activity.

Contraindications

The drug is prescribed with caution when performing heavy physical exertion, because this can lead to ketoacidosis. The use of Glucophage Long 500 for weight loss has a number of contraindications. These include:

• renal failure - due to a possible exacerbation of the disease and general intoxication;
• impaired renal function - fever, dehydration, prolonged diarrhea, poisoning, acute infections, persistent vomiting;
• cardiac, pulmonary insufficiency, performed operations on the heart or lungs;
• liver injury;
• low-calorie diet containing less than 1000 kcal per day;
• pregnancy, breastfeeding (lactation);
• ketoacidosis;
• acute myocardial infarction;
• age up to 18 and over 65;
• alcoholism, acute alcohol intoxication;
• individual intolerance to the components of the composition.

How to take Glucophage Long 500 for weight loss

Tablets for weight loss are taken once a day, since metformin is a substance with a long absorption and long-lasting effect. The first 3-5 days are taken 1 tablet per day. With excess weight over 20 kg and a favorable response to the drug, you can increase the dosage to 2 capsules (1000 mg / day). Glucophage is taken in the morning or afternoon with a meal, washed down with a glass of water. The course of treatment is 3 weeks, then a break is made for 2 months.

If you take diet pills without interruption, their effect is significantly reduced. After a well-tolerated initial course, it is allowed to repeat the dose at an increased dose. The maximum daily dosage will be 2000 mg of metformin in two doses with intervals of at least 8 hours between them. During treatment, it is necessary to drink more water in order to excrete the breakdown products of the drug by the kidneys without toxic effects.

A month before the planned conception, it is required to stop taking pills. If pregnancy occurs during treatment with metformin, you should immediately consult a doctor. It is also necessary to stop taking the tablets two days before the X-ray with the use of contrast agents based on iodine compounds. Treatment is resumed two days after the procedure. A number of special instructions for the use of medication for weight loss:

1. Due to the accumulation of metformin in patients, lactic acidosis (accumulation of toxic substances) can occur, which leads to death in the absence of urgent treatment. Cases of complications are more pronounced in patients with diabetes mellitus on the background of renal failure. Prolonged fasting and drinking alcohol can aggravate the condition.
2. Symptoms of lactic acidosis: shortness of breath, abdominal pain, hypothermia, coma.
3. Metformin should be discontinued 2 days before surgery, and resumed 2 days after.
4. Serum creatinine or its clearance should be determined before starting administration in order to avoid complications of kidney function.
5. Caution in taking Glucophage for weight loss should be observed when combined with antihypertensive drugs, diuretics, non-steroidal anti-inflammatory drugs. It is not recommended to take pills for bronchopulmonary infections, infectious diseases of the genitourinary tract.
6. Taking the drug does not affect the ability to concentrate, think clearly, so driving and dangerous mechanisms is not forbidden.

Compatibility with other medicines

To reduce the possible toxic manifestations of Glucophage and avoid side effects, it is recommended not to combine the intake of diet pills with certain medications. These include:

• drugs that reduce sugar levels, if their combined use is not prescribed by a doctor;
• antipsychotics, antidepressants, stimulants;
• alcohol and medicines containing it;
• loop diuretics;
• antihypertensive (lowering blood pressure) drugs;
• cationic drugs secreted in the renal tubules (Digoxin, Quinine, Quinidine, Morphine);
• sulfonylurea derivatives, acarbose, salicylates (hypoglycemia may develop).

Side effects

The risk of side effects after taking Glucophage Long 500 for weight loss remains at a high level. Possible negative effects include:

• digestive and taste disorders, metallic taste in the mouth, vomiting, nausea;
• skin rashes, ulcers, itching, erythema, allergic reactions (to exclude them, you need to start taking the lowest possible test dose of 500 mg and then gradually increase it);
• lactic acidosis;
• nervous tension;
• diarrhea, constipation, cramps in the stomach, intestines, colic, abdominal pain, digestive tract disorders;
• increased heart rate, heart pain, shortness of breath;
• dizziness, blind spots or circles before the eyes, confusion, loss of concentration, headache.

An overdose of metformin during weight loss leads to the development of lactic acidosis, which can be fatal. If the dose is exceeded several times, it is urgent to seek medical help. Doctors determine the level of lactate, clarify the diagnosis and conduct symptomatic therapy. Hemodialysis is used to remove toxins.

Price for Glucophage Long 500

You can buy Glucophage tablets not only at a concentration of 500 mg. There are other options. Their cost depends on the concentration of metformin, the number of tablets in the package, the level of the trade margin. Approximate prices for a medicine for weight loss in Moscow and St. Petersburg will be:

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